CN107715097A - A kind of Chinese medicine composition for treating stomach energy sour regurgitation and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating stomach energy sour regurgitation and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/55—Liquid-liquid separation; Phase separation
Abstract
The present invention relates to a kind of Chinese medicine composition for treating stomach energy sour regurgitation and preparation method thereof.The Chinese medicine is prepared by Chinese medicine materials such as radix glehniae, corydalis tuber, Ligusticum wallichii, ginger, Fructus meliae toosendan, dried orange peel, peel of cape jasmine fruit, the tuber of dwarf lilyturf, balloonflower root, the wind-weed, radix glycyrrhizaes.Present invention also offers the preparation method of this Chinese medicine composition.Chinese medicine composition provided by the invention is mainly used in treating stomach energy sour regurgitation.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating stomach energy sour regurgitation and preparation method thereof.
Background technology
Stomach energy is a kind of disease of tcm, i.e. stomach fire, more by heat invading the stomach；Or because being addicted to drink, addiction is pungent, overfeeding fat meat and fine grain is thick
Taste, help fiery heat；The fire of liver and gall, perverse and unreasonable manner violate stomach, can also cause stomach energy（Stomach fire）.The traditional Chinese medical science is divided into the strongly fragrant stomach of heat, it is scorching in fire-evil and
Burning hot tenesmus etc..Flaring up of stomach fire, stomach Qi upward reversal can be caused, it is seen that the disease such as nausea, sour regurgitation water.
The reason for causing stomach energy has a lot, is addicted to drink, addiction is pungent, the excessive improper diet problems such as rich food that eat all may be used
Stomach energy can be caused;And the stagnation of the circulation of vital energy, blood stasis, phlegm, wet, dyspepsia etc. also can pent-upization heat, change fire, cause stomach energy (stomach fire);In addition, liver stomach
Discord, can also cause stomach energy (stomach fire).
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating stomach energy sour regurgitation；
It is a further object of the present invention to provide a kind of preparation method for the Chinese medicine composition for treating stomach energy sour regurgitation.
The purpose of the present invention is realized by following technical scheme：
The Chinese medicine composition for the treatment of stomach energy sour regurgitation of the present invention, is prepared by the Chinese medicine material of following parts by weight：
Radix glehniae 20-40 parts, corydalis tuber 5-20 parts, Ligusticum wallichii 10-30 parts, ginger 5-20 parts, Fructus meliae toosendan 10-30 parts, dried orange peel 5-20
Part, peel of cape jasmine fruit 5-20 parts, tuber of dwarf lilyturf 10-30 part, balloonflower root 10-30 parts, wind-weed 20-40 parts, radix glycyrrhizae 20-40 parts.
Preferably, it is to be prepared by the Chinese medicine material of following parts by weight：
Radix glehniae 25-35 parts, corydalis tuber 10-15 parts, Ligusticum wallichii 15-25 parts, ginger 10-15 parts, Fructus meliae toosendan 15-25 parts, dried orange peel 10-
15 parts, peel of cape jasmine fruit 10-15 parts, tuber of dwarf lilyturf 15-25 part, balloonflower root 15-25 parts, wind-weed 25-35 parts, radix glycyrrhizae 25-35 parts.
It is the crude drug source of Chinese medicine preparation of the present invention below：
Radix glehniae, it is samphire glehnia littoralis Glehnia littoralis Fr. Schmidt ex Miq. dry root.
Sweet, slight bitter, is slightly cold.Attach to the lung and stomach meridians.Nourishiing yin to clear away the lung-heat, reinforcing stomach reg fluid.For lung-heat type cough, overstrain cough phlegm blood, pyreticosis injury thirst.
Corydalis tuber, it is papaveraceae plant corydalis Corydalis yanhusuo W. T. Wang dry tuber.Pungent,
Hardship, temperature.Return liver, the spleen channel.Promoting blood circulation, sharp gas, analgesic.For chest side of body, epigastric pain, closed dysmenorrhea, postpartum stasis, tumbling and swelling.
Ligusticum wallichii, it is samphire Ligusticum wallichii Ligusticum chuanxiong Hort.（Or Ligusticum
wallichii Franch.）Dry rhizome.It is pungent, temperature.Return liver, courage, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menstruation
It is uncomfortable, closed dysmenorrhea, abdominal mass stomachache, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism.
Ginger, it is Zingiber herbaceos perennial ginger（Zingiber officinale Roscoe）New fresh quench stem.Have
Diverging, preventing or arresting vomiting, cough-relieving and other effects.
Fructus meliae toosendan, it is Meliaceae plant melia toosendan Melia toosendan Sieb. et Zucc. dry mature fruit.Hardship,
It is cold；It is slightly poisonous.Return liver, small intestine, bladder warp.Easypro liver promoting qi circulation and relieving pain, expelling parasite.For chest side of body, abdominal distention, colic, abdominal pain due to enterositosis.
Dried orange peel, it is the drying and ripening fruit of rutaceae orange Citrus reticulata Blanco and its variety
Skin.It is bitter, pungent, temperature.Return lung, the spleen channel.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For chest gastral cavity turgor, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
Peel of cape jasmine fruit, it is the root of Flacourtiaceae plant peel of cape jasmine fruit.Hardship, put down.Liver Channel.Clearing damp stagnation resolvation.With controlling rheumatism bi Zheng, joint
Pain, hands and feet caused by paralysis, traumatic injury, blood stasis and swelling pain, rheumatism.
The tuber of dwarf lilyturf, it is the liliaceous plant tuber of dwarf lilyturf（Dwarf lilyturf）Ophiopogon japonicus （Thunb.）Ker-Gawl.
Dried root.It is sweet, slight bitter, it is slightly cold.The thoughts of returning home, lung, stomach.Nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire.For dryness of the lung dry cough.Tuberculosis cough, Tianjin
Wound is thirsty, vexed insomnia, Heat Diabetes, dry constipation of intestines；Pharyngeal diphtheria.
Balloonflower root, it is Campanulaceae balloonflower root Platycodon grandiflorum（Jacq.）A.DC. dry root.Bitter,
It is pungent, put down.Return lung passes through.Facilitaing lung, relieving sore-throat, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia, sound is mute, lung carbuncle pyemesis, sore
Ulcer purulence is not into bursting.
The wind-weed, it is liliaceous plant wind-weed Anemarrhena asphodeloides Bunge. dry rhizome.Bitter,
It is sweet, tremble with fear.Return lung, stomach, kidney channel.Clearing heat-fire, fluid dryness.For fever caused by exogenous pathogenic factors, hyperpyrexia polydipsia, lung-heat type cough, osteopyrexia and fever,
Heat Diabetes, dry constipation of intestines.
Radix glycyrrhizae, it is glycyrrhizic legume Glycyrrhiza uralensis Fisch., swollen fruit Radix Glycyrrhiza
Inflata Bat. or glycyrrhiza glabra Glycyrrhiza glabra L. dry root.It is sweet, put down.The thoughts of returning home, lung, spleen, stomach
.Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation,
Coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Another aspect of the present invention there is provided the preparation method of the active component of Chinese medicine composition of the present invention, and this method is
It is prepared using the extraction of the ethanol of water extraction or 40-80% concentration expressed in percentage by volumes.Specific preparation method is as follows：
Scheme one：Take whole medicinal materials, extracting in water 2-3 times after mixing, each amount of water equivalent to 6-12 times of medicinal material gross weight,
Each extraction time is 1-3 hours, merges extract solution, filtration, relative density is 1.15-1.20 when filtrate is concentrated into 70-80 DEG C
Clear cream, produce active component.
Scheme two：Whole medicinal materials are taken, are extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is medicinal material total amount
4-10 times, extraction time is 1-4 hours, merge extract solution, filtering, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, produces active component.
Scheme three：Whole medicinal materials are taken, extracting in water 2-3 times after mixing, 6- of each amount of water equivalent to medicinal material gross weight
12 times, each extraction time is 1-3 hours, merges extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, ethanol is added, it is 40-70% to make alcohol content, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80
DEG C when relative density be 1.10-1.25 medicinal extract, produce active component.
The Chinese medicine composition for the treatment of stomach energy sour regurgitation of the present invention, can also match somebody with somebody with pharmaceutically acceptable carrier
Close, various oral formulations, such as pill, tablet, capsule, oral liquid, syrup, mixture are made.
The pharmaceutically acceptable carrier of the present invention includes but is not limited to following：
Oral formulations：
Diluent：Starch, Icing Sugar, lactose, dextrin, microcrystalline cellulose, inorganic salts, glycitols etc..
Wetting agent and adhesive：Purified water, ethanol, gelatin, polyethylene glycol, cellulose derivative etc..
Disintegrant：Starch, sodium carboxymethyl starch, cellulose derivative, PVPP etc..
Lubricant：Magnesium stearate, superfine silica gel powder, talcum powder, polyethylene glycol etc..
Cosolvent：Water, ethanol, glycerine, propane diols, liquid paraffin, vegetable oil etc..
Flavouring：Sucrose, monose, aromatic etc..
Preservative：Benzoic acid, sorbic acid, methyl esters, ethyl ester, propyl ester etc..
Method 1：Tablet
Scheme one is taken to add tablet and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention tablet.
Above-mentioned tablet often includes one of diluent, wetting agent, adhesive, disintegrant, lubricant or whole with auxiliary material.
Method 2：Capsule
Scheme one is taken to add capsule and often use auxiliary material, routinely production method is prepared into one of to the gained active component of scheme three
Capsule of the present invention.
Above-mentioned capsule often includes one of diluent, wetting agent, adhesive, disintegrant, lubricant or whole with auxiliary material.
Method 3：Syrup
Scheme one is taken to add syrup and often use auxiliary material, routinely production method is prepared into one of to the gained active component of scheme three
Syrup of the present invention.
Above-mentioned syrup often includes one of flavouring, preservative, cosolvent or whole with auxiliary material.
Method 4：Mixture
Scheme one is taken to add mixture and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention mixture.
Above-mentioned mixture often includes one of flavouring, preservative or whole with auxiliary material.
Method 5：Oral liquid
Scheme one is taken dissolving after-purification, concentration, to add oral liquid and often use auxiliary material, by normal one of to the gained active component of scheme three
Rule production method is prepared into oral liquid of the present invention.
A kind of Chinese medicine composition for treating stomach energy sour regurgitation provided by the invention has advantages below：
1st, composite preparation provided by the invention is safe and effective, has clearing away the stomach-heat, rushes down stomach fire, suppresses sour water, promote WeiDongLi Capsule it
Effect.Treatment for stomach energy sour regurgitation.
2nd, clinical tests prove that, after being treated with the present invention to heating infant, effective percentage shows the present invention up to 95.31%
Stomach energy sour regurgitation can effectively be treated.
3rd, Chinese medicinal composition preparation provided by the invention, scientific formulation is reasonable, and technique is simple, in good taste, and cost is low.
Embodiment
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are to be used to illustrate
The present invention rather than limitation of the present invention.The present invention is belonged to according to the simple modifications that the essence of the present invention is carried out to the present invention
Claimed scope.Unless otherwise indicated, the percentage of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution
Volume ratio.
The granule of embodiment 1
Weigh radix glehniae 20g, corydalis tuber 5g, Ligusticum wallichii 10g, ginger 5g, Fructus meliae toosendan 10g, dried orange peel 5g, peel of cape jasmine fruit 5g, tuber of dwarf lilyturf 10g,
Balloonflower root 10g, wind-weed 20g, radix glycyrrhizae 20g.Extracting in water 3 times, amount of water is respectively 12 times of medicinal material gross weight, 8 times, 6 times three times,
Extraction time is respectively 3 hours, 2 hours, 1 hour three times, merges extract solution, filtration, relative density when filtrate is concentrated into 70 DEG C
For 1.25 clear cream, starch, dextrin are added, granulation, dry, whole grain produce.
The tablet of embodiment 2
Weigh radix glehniae 40g, corydalis tuber 20g, Ligusticum wallichii 30g, ginger 20g, Fructus meliae toosendan 30g, dried orange peel 20g, peel of cape jasmine fruit 20g, the tuber of dwarf lilyturf
30g, balloonflower root 30g, wind-weed 40g, radix glycyrrhizae 40g.Extracted 2 times with alcohol reflux, each concentration of alcohol is respectively 80%, 60%, every time
Ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, and extraction time is respectively 4 hours, 3 hours, merges extract solution, is filtered, filter
Relative density is 1.10 medicinal extract when liquid is concentrated into 80 DEG C, adds supplementary product starch, ethanol, talcum powder, and tablet is made.
The tablet of embodiment 3
Weigh radix glehniae 25g, corydalis tuber 10g, Ligusticum wallichii 15g, ginger 10g, Fructus meliae toosendan 15g, dried orange peel 10g, peel of cape jasmine fruit 10g, the tuber of dwarf lilyturf
15g, balloonflower root 15g, wind-weed 25g, radix glycyrrhizae 25g.Extracting in water 3 times, three times amount of water be respectively equivalent to 12 times of medicinal material gross weight,
8 times, 6 times, each extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, filtration, and filtrate is concentrated into 70 DEG C of phases
To the clear cream that density is 1.20, ethanol is added, it is 40% to make alcohol content, stands 24 hours, filtration, and filtrate is concentrated into filtrate concentration
To the medicinal extract that relative density at 70 DEG C is 1.10, supplementary product starch, ethanol, talcum powder are added, tablet is made.
The capsule of embodiment 4
Weigh radix glehniae 35g, corydalis tuber 15g, Ligusticum wallichii 25g, ginger 15g, Fructus meliae toosendan 25g, dried orange peel 15g, peel of cape jasmine fruit 15g, the tuber of dwarf lilyturf
25g, balloonflower root 25g, wind-weed 35g, radix glycyrrhizae 35g.Extracted 3 times with 40% alcohol reflux, each ethanol consumption is respectively medicinal material total amount
10 times, 8 times, 4 times, extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, filtering, and filtrate concentrates relative at 60 DEG C
Density is 1.25 medicinal extract, and supplementary product starch, ethanol, dextrin, magnesium stearate are added in medicinal extract, capsule is made according to a conventional method
Agent.
The granule of embodiment 5
Weigh radix glehniae 30g, corydalis tuber 12g, Ligusticum wallichii 20g, ginger 12g, Fructus meliae toosendan 20g, dried orange peel 12g, peel of cape jasmine fruit 12g, the tuber of dwarf lilyturf
20g, balloonflower root 20g, wind-weed 30g, radix glycyrrhizae 30g.Extracting in water 2 times, each amount of water be respectively equivalent to 12 times of medicinal material gross weight,
10 times, each extraction time is respectively 3 hours, 2 hours, merges extract solution, filtration, and filtrate is concentrated into relative density at 80 DEG C and is
1.05 clear cream, ethanol is added, it is 70% to make alcohol content, stands 12 hours, and filtration, relative density is when filtrate is concentrated into 70 DEG C
1.25 medicinal extract, adds starch, dextrin, and granulation, dry, whole grain produce.
The syrup of embodiment 6
Weigh radix glehniae 23g, corydalis tuber 8g, Ligusticum wallichii 12g, ginger 8g, Fructus meliae toosendan 12g, dried orange peel 8g, peel of cape jasmine fruit 8g, tuber of dwarf lilyturf 12g,
Balloonflower root 12g, wind-weed 23g, radix glycyrrhizae 23g.Extracting in water 2 times, amount of water is respectively 10 times of medicinal material gross weight, 8 times twice, twice
Extraction time is respectively 2 hours, 1 hour, merges extract solution, filtration, relative density is 1.10 leaching when filtrate is concentrated into 80 DEG C
Cream.Syrup auxiliary material sucrose, sorbic acid, water are added in medicinal extract to stir, and syrup is made.
The oral liquid of embodiment 7
Weigh radix glehniae 28g, corydalis tuber 11g, Ligusticum wallichii 18g, ginger 11g, Fructus meliae toosendan 18g, dried orange peel 11g, peel of cape jasmine fruit 11g, the tuber of dwarf lilyturf
18g, balloonflower root 18g, wind-weed 28g, radix glycyrrhizae 28g.Extracting in water 2 times, amount of water is respectively 10 times of medicinal material gross weight, 8 times twice,
Extraction time is respectively 2 hours, 1 hour twice, merges extract solution, filtration, relative density is 1.10 when filtrate is concentrated into 80 DEG C
Medicinal extract, in medicinal extract adding auxiliary material mannitol, sorbic acid, water stirs, and dispenses, oral liquid is made.
The mixture of embodiment 8
Weigh radix glehniae 32g, corydalis tuber 14g, Ligusticum wallichii 23g, ginger 14g, Fructus meliae toosendan 23g, dried orange peel 14g, peel of cape jasmine fruit 14g, the tuber of dwarf lilyturf
23g, balloonflower root 23g, wind-weed 32g, radix glycyrrhizae 32g.Extracting in water 3 times, three times amount of water be respectively equivalent to 12 times of medicinal material gross weight,
8 times, 6 times, each extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, filtration, and filtrate concentration ad pond om is
3 times of medicinal material gross weight, it is filling, add mixture auxiliary material sucrose, ethyl ester, water, sorbic acid and stir, mixture is made.
The pulvis of embodiment 9
Weigh radix glehniae 38g, corydalis tuber 18g, Ligusticum wallichii 28g, ginger 18g, Fructus meliae toosendan 28g, dried orange peel 18g, peel of cape jasmine fruit 18g, the tuber of dwarf lilyturf
28g, balloonflower root 28g, wind-weed 38g, radix glycyrrhizae 38g.Crush, sieving, produce.
Claims (7)
- A kind of 1. Chinese medicine composition for treating stomach energy sour regurgitation, it is characterised in that it be by following parts by weight Chinese medicine material prepare and Into：Radix glehniae 20-40 parts, corydalis tuber 5-20 parts, Ligusticum wallichii 10-30 parts, ginger 5-20 parts, Fructus meliae toosendan 10-30 parts, dried orange peel 5-20 Part, peel of cape jasmine fruit 5-20 parts, tuber of dwarf lilyturf 10-30 part, balloonflower root 10-30 parts, wind-weed 20-40 parts, radix glycyrrhizae 20-40 parts.
- 2. the Chinese medicine composition for the treatment of stomach energy sour regurgitation as claimed in claim 1, it is characterised in that it is by including following weight What the Chinese medicine material of part was prepared：Radix glehniae 25-35 parts, corydalis tuber 10-15 parts, Ligusticum wallichii 15-25 parts, ginger 10-15 parts, Fructus meliae toosendan 15-25 parts, dried orange peel 10- 15 parts, peel of cape jasmine fruit 10-15 parts, tuber of dwarf lilyturf 15-25 part, balloonflower root 15-25 parts, wind-weed 25-35 parts, radix glycyrrhizae 25-35 parts.
- 3. the Chinese medicine composition for the treatment of stomach energy sour regurgitation as claimed in claim 1 or 2, it is characterised in that its active component is to adopt It is prepared with the extraction of the ethanol of water extraction or 40-80% concentration expressed in percentage by volumes.
- 4. the Chinese medicine composition for the treatment of stomach energy sour regurgitation as claimed in claim 3, it is characterised in that its active component is to pass through What following methods were prepared：Whole medicinal materials are taken, extracting in water 2-3 times after mixing, each amount of water is equivalent to medicinal material gross weight 6-12 times, each extraction time is 1-3 hours, merge extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream, produces active component.
- 5. the Chinese medicine composition for the treatment of stomach energy sour regurgitation as claimed in claim 3, it is characterised in that its active component is to pass through What following methods were prepared：Whole medicinal materials are taken, are extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is 4-10 times of medicinal material total amount, extraction time are 1-4 hours, merge extract solution, filtering, filtrate is concentrated into relatively close at 70-80 DEG C The clear cream for 1.15-1.20 is spent, produces active component.
- 6. the Chinese medicine composition for the treatment of stomach energy sour regurgitation as claimed in claim 3, it is characterised in that its active component is to pass through What following methods were prepared：Whole medicinal materials are taken, extracting in water 2-3 times after mixing, each amount of water is equivalent to medicinal material gross weight 6-12 times, each extraction time is 1-3 hours, merge extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream, ethanol is added, it is 40-70% to make alcohol content, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80 DEG C when relative density be 1.10-1.25 medicinal extract, produce active component.
- 7. a kind of preparation for treating stomach energy sour regurgitation, Chinese medicine composition and doctor as the treatment stomach energy sour regurgitation described in claim 1-6 Pharmaceutically acceptable carrier, which prepares, to be formed.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877476A (en) * | 2014-04-11 | 2014-06-25 | 刘宝昌 | Traditional Chinese medicine composition for treating gastropathy |
| CN105796712A (en) * | 2016-06-03 | 2016-07-27 | 胡晨 | Traditional Chinese medicine composition for treatment of superficial gastritis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877476A (en) * | 2014-04-11 | 2014-06-25 | 刘宝昌 | Traditional Chinese medicine composition for treating gastropathy |
| CN105796712A (en) * | 2016-06-03 | 2016-07-27 | 胡晨 | Traditional Chinese medicine composition for treatment of superficial gastritis |
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Application publication date: 20180223 |