CN107699488A - Tunable cell culture dish scoring devices - Google Patents
Tunable cell culture dish scoring devices Download PDFInfo
- Publication number
- CN107699488A CN107699488A CN201711180185.9A CN201711180185A CN107699488A CN 107699488 A CN107699488 A CN 107699488A CN 201711180185 A CN201711180185 A CN 201711180185A CN 107699488 A CN107699488 A CN 107699488A
- Authority
- CN
- China
- Prior art keywords
- fixator
- lifting platform
- chute
- cell
- gear
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Clinical Laboratory Science (AREA)
- Mechanical Engineering (AREA)
- Analytical Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a kind of tunable cell culture dish scoring devices, it is made up of table mechanism, operating mechanism and controlling organization, operating mechanism and controlling organization are separately positioned on table mechanism；In use, culture dish is placed on working plate, operating mechanism can move up and down in elevating lever, cell scratch depth can be observed by display screen, mutually it is engaged with gear grooved by gear, can adjust the movable of screeding device, cell cut length can be observed by display screen；The present invention is scientific and reasonable for structure, it is easy to operate, width and the cut of depth can be fixed with point-device, scratch depth can adjust, and not influence the bed board material of cell bottom, cut registration, scratch width can carry out drawing plate according to different cut instruments, can observe the ability level of cell migration, have video camera accessory system, line width, depth intense adjustment can be entered, improve cell cut quality.
Description
Technical field
The present invention relates to a kind of medicine equipment, more particularly to a kind of tunable cell culture dish scoring devices.
Background technology
Regular noun of the cell culture in biology is cell culture technology, no matter for whole biotechnology,
Or for the biological cloning technology of one of them, cell culture is all an essential process, and cell culture is inherently
It is the extensive clone of cell.Cell culture technology can turn into simple unicellular or pole by a cell by mass propgation
The many cells broken up less, this is the essential link of clone technology, and the clone of cell culture inherently cell, is passed through
Cell culture obtains substantial amounts of cell or its metabolite, because biological product is got from cell, it is possible to say cell
Culture technique is most crucial, most basic technology in biotechnology.
Cell scratch experiment, refer to by cell culture on culture dish or flat board, drawn after cell fusion in middle section
One line, the cell in this line are got rid of by mechanical force, then continue to cultivate by cell, and observation cell is drawn to acellular
The situation of trace zone migration, to judge the transfer ability of cell.
Existing cell cut is manual cut mostly, and manual cut, using sample-adding pipette tips cut, exists generally on culture dish
Following shortcoming：
Occurs rigid cut on culture dish：The purpose of cut is usually used in assessing the ability level of cell migration, manual cut
The gimmick of several weeks is often needed to practise cut, manual cut occurring rigid on vessel flat board on the cell plates for needing to detect
It is also common to scratch, and influences the observation of cell migration, and manual scratch width can not be grasped, can not using sample-adding pipette tips scratch width
It is determined that randomness is strong, manual scratch depth can not control, and scoring operation person is often because can not smooth culture dish bottom residual at cut
Cell, manual two pieces of culture dish cut contrasts of cut are inconsistent, often contrast not objective enough, manual cut because scratch width is inconsistent
Width can not be accurate to scale, position inaccurate, multiple observation same position mobilance again after being positioned after cut, after manual cut
The position of positioning can not be accurate to, often cut is straight after manual cut, irregularity, and observing effect is bad, and manual cut can not be again
Fixed thickness is retained on culture dish, born of the same parents' culture is in bottom tiling culture materials or gel, or cell is multilayer, and manual cut can not
Accomplish to retain fixed thickness base material.
The content of the invention
It is manual cut institute produced problem present invention aim to address cell cut in above-mentioned background technology, and provides
A kind of tunable cell culture dish scoring devices.
Tunable cell culture dish scoring devices, are made up of table mechanism, operating mechanism and controlling organization, operate machine
Structure and controlling organization are separately positioned on table mechanism；
Table mechanism includes working plate, the first fixator, the second fixator, the 3rd fixator, elevating lever and culture
Ware, the first fixator, the second fixator, the 3rd fixator, elevating lever and culture dish are separately positioned on working plate, elevating lever
Working plate rear end is fixedly installed on, before the first fixator, the second fixator and the 3rd fixator are separately positioned on working plate
End, culture dish is arranged between the first fixator, the second fixator and the 3rd fixator, the first fixator, the second fixator and
3rd fixer structure is identical；
First fixator includes the first fixed block, fixing bolt and the second fixed block, the first fixed block and the second fixed block
Structure is identical, and is respectively fixedly disposed on working plate, and the first fixed block and the second fixed block upper end have in first respectively
Screwed hole, fixing bolt are each passed through the first internal thread hole of the first fixed block and the second fixed block, in fixing bolt and first
Corresponding threaded holes close；
There is the first graduation mark on elevating lever；
Operating mechanism includes fixed lowering or hoisting gear, screeding device and drive device, and fixed lowering or hoisting gear is arranged on elevating lever
On, screeding device and drive device are separately positioned on fixed lowering or hoisting gear,
Fixed lowering or hoisting gear includes fixes sleeve, the first fixation lifting platform, the second fixation lifting platform and the first leading screw rotating shaft,
First fixation lifting platform and the second fixation lifting platform are separately positioned on fixes sleeve rear end, and first, which fixes lifting platform and second, fixes
There is the second coaxial internal thread hole respectively, the first leading screw rotating shaft upper end has first-hand, and lower end has first on lifting platform
Leading screw, the first leading screw rotating shaft are fixed lifting platform and second through first and fixed in the second internal thread hole of lifting platform, the first leading screw
It is engaged with the second internal thread hole；
There is clamping screw in fixes sleeve；
The structure on two sides of first fixation lifting platform is identical, and front end has the first chute, and upper end has the second chute, and second slides
Groove both sides have the second graduation mark；
The structure on two sides of second fixation lifting platform is identical, and front end has the 3rd chute, has gear grooved on the 3rd chute,
Screeding device includes the first slide bar, the second slide bar, connecting rod and draws head, and the first slide bar and the second slide bar are fixed respectively
Connecting rod upper/lower terminal is arranged on, the first slide bar both ends have pointer head respectively, and connecting rod lower end has jointing, draw head
Jointing lower end is arranged on, the first slide bar is arranged in the first chute, and the second slide bar is arranged in the 3rd chute, and pointer head is set
Put on the second chute；
Drive device includes the second rotating shaft and driver, and the second rotating shaft is arranged in driver, has the in the second rotating shaft
Second chief and axostylus axostyle, driver is interior to have gear, and gear is arranged on axostylus axostyle, and gear is mutually engaged with gear grooved；
Controlling organization includes the first image pick-up device, the second image pick-up device and display screen, and the first image pick-up device, the second image pick-up device are set respectively
Put on working plate, the first image pick-up device and the second image pick-up device are connected with display screen respectively.
The operation principle and process of the present invention：
In use, culture dish is placed between the first fixator, the second fixator and the 3rd fixator, rotary fixing screw
Bolt, fixing bolt are engaged with the first internal thread hole, and the first fixator, the second fixator and the 3rd fixator are engaged fixed training
Ware is supported, the right position of culture dish can be adjusted, first-hand of the first leading screw rotating shaft is rotated, by the first leading screw and second
Corresponding threaded holes close, and operating mechanism can move up and down in elevating lever, and the first image pick-up device and the second image pick-up device can accurate observation stroke heads
With the position relationship of cell, cell scratch depth can be observed by display screen, to according to necessary requirement, pass through the first of elevating lever
Graduation mark is engaged, and is adjusted the height for drawing head, is rotated the second in command of the second rotating shaft, is mutually stung with gear grooved by gear
Close, can adjust the movable of screeding device, by the second graduation mark, observable draw head movement front and rear in culture dish away from
From, can by display screen observe cell cut length, clamping screw can fixed operation mechanism fixation lowering or hoisting gear.
Beneficial effects of the present invention：
The present invention is scientific and reasonable for structure, easy to operate, it is not necessary to further processing, width can be fixed with point-device
The cut of degree and depth, scratch depth can adjust, and not influence the bed board material of cell bottom, cut registration, and cut is wide
Degree can carry out drawing plate according to different cut instruments, can observe the ability level of cell migration, have video camera auxiliary system
System, line width, depth intense adjustment can be entered, improve cell cut quality.
Brief description of the drawings
Fig. 1 is the partial structural diagram of the present invention.
Fig. 2 is the structural representation of the present invention.
Fig. 3 is the structural representation of the present invention.
Fig. 4 is the partial structural diagram of the present invention.
Fig. 5 is the structural representation of cut mechanism of the present invention.
Fig. 6 is the structural representation that the present invention draws head first embodiment.
Fig. 7 is the structural representation that the present invention draws head second embodiment.
Fig. 8 is the structural representation of culture dish of the present invention.
Embodiment
Refer to shown in Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7 and Fig. 8, tunable cell culture dish scoring devices,
It is made up of table mechanism 1, operating mechanism 2 and controlling organization 3, operating mechanism 2 and controlling organization 3 are separately positioned on workbench
In mechanism 1；
Table mechanism 1 includes working plate 11, the first fixator 12, the second fixator 13, the 3rd fixator 14, lifting
Bar 15 and culture dish 17, the first fixator 12, the second fixator 13, the 3rd fixator 14, elevating lever 15 and culture dish 17 are distinguished
It is arranged on working plate 11, elevating lever 15 is fixedly installed on the rear end of working plate 11, the first fixator 12, the second fixator 13
The front end of working plate 11 is separately positioned on the 3rd fixator 14, culture dish 17 is arranged on the first fixator 12, the second fixator
13 and the 3rd between fixator 14, and the first fixator 12, the second fixator 13 are identical with the structure of the 3rd fixator 14；
First fixator 12 includes the first fixed block 121, the fixed block 123 of fixing bolt 122 and second, the first fixed block
121 is identical with the structure of the second fixed block 123, and is respectively fixedly disposed on working plate 11, and the first fixed block 121 and second is solid
Determine the upper end of block 123 has the first internal thread hole respectively, and fixing bolt 122 is each passed through the first fixed block 121 and the second fixed block
123 the first internal thread hole, fixing bolt 122 are engaged with the first internal thread hole；
There is the first graduation mark 151 on elevating lever 15；
Operating mechanism 2 includes fixed lowering or hoisting gear 21, screeding device 22 and drive device 23, and fixed lowering or hoisting gear 21 is set
On elevating lever 15, screeding device 22 and drive device 23 are separately positioned on fixed lowering or hoisting gear 21,
Fixed lowering or hoisting gear 21, which includes fixes sleeve 211, first, to be fixed lifting platform 212, second and fixes lifting platform 213 and the
One leading screw rotating shaft 16, the first fixation lifting platform 212 and second fix lifting platform 213 and are separately positioned on the rear end of fixes sleeve 211, the
One, which fixes lifting platform 212 and second, fixes on lifting platform 213 respectively with the second coaxial internal thread hole, the first leading screw rotating shaft 16
Upper end has first-hand 161, and lower end has the first leading screw 162, and the first leading screw rotating shaft 16 fixes the He of lifting platform 212 through first
Second is fixed in the second internal thread hole of lifting platform 213, and the first leading screw 162 is engaged with the second internal thread hole；
There is clamping screw 2111 in fixes sleeve 211；
The structure on two sides of first fixation lifting platform 212 is identical, and front end has the first chute 2121, and upper end has the second chute
2122, the both sides of the second chute 2122 have the second graduation mark 2123；
The structure on two sides of second fixation lifting platform 213 is identical, and front end has the 3rd chute 2131, has on the 3rd chute 2131
There is gear grooved,
Screeding device 22 includes the first slide bar 221, the second slide bar 222, connecting rod 223 and draws first 225, the first slide bar 221
The upper/lower terminal of connecting rod 223 is respectively fixedly disposed at the second slide bar 222, the both ends of the first slide bar 221 have pointer head respectively
226, the lower end of connecting rod 223 has jointing 224, draws first 225 and is arranged on the lower end of jointing 224, the first slide bar 221 is set
In the first chute 2121, the second slide bar 222 is arranged in the 3rd chute 2131, and pointer first 226 is arranged on the second chute 2122
On；
Drive device 23 includes the second rotating shaft 231 and driver 232, and the second rotating shaft 231 is arranged in driver 232, the
There is the second in command 233 and axostylus axostyle in two rotating shafts 231, there is gear in driver 232, gear is arranged on axostylus axostyle, gear and
Gear grooved is mutually engaged；
Controlling organization 3 includes the first image pick-up device 31, the second image pick-up device 32 and display screen 33, and the first image pick-up device 31, second are taken the photograph
As device 32 is separately positioned on working plate 11, the first image pick-up device 31 and the second image pick-up device 32 are connected with display screen 33 respectively.
The operation principle and process of the present invention：
Refer to shown in Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7 and Fig. 8, in use, culture dish 17 is placed on into first
Between fixator 12, the second fixator 13 and the 3rd fixator 14, rotary fixing screw bolt 122, spiral shell in fixing bolt 122 and first
Pit is engaged, and the first fixator 12, the second fixator 13 and the 3rd fixator 14 are engaged fixed culture dish 17, can adjust
The right position of culture dish 17, the first-hand 161 of the first leading screw rotating shaft 16 is rotated, passes through spiral shell in the first leading screw 162 and second
Pit is engaged, and operating mechanism 2 can move up and down in elevating lever 15, and the first image pick-up device 31 and the second image pick-up device 32 can accurately be seen
Examine and draw first 225 position relationships with cell, cell scratch depth can be observed by display screen, to according to necessary requirement, pass through liter
Drop bar 15 the first graduation mark 151 be engaged, be adjusted draw first 22 height, rotate the second rotating shaft 231 the second in command
233, mutually it is engaged with gear grooved by gear, can adjust the movable of screeding device 22, it is considerable by the second graduation mark 2123
Examine and draw first 225 displacements front and rear in culture dish 17, cell cut length, clamping screw 2111 can be observed by display screen
Can fixed operation mechanism 2 fixation lowering or hoisting gear 21.
Claims (1)
1. a kind of tunable cell culture dish scoring devices, it is by table mechanism (1), operating mechanism (2) and controlling organization (3)
Composition, operating mechanism (2) and controlling organization (3) are separately positioned on table mechanism (1)；
Table mechanism (1) includes working plate (11), the first fixator (12), the second fixator (13), the 3rd fixator
(14), elevating lever (15) and culture dish (17), the first fixator (12), the second fixator (13), the 3rd fixator (14), lifting
Bar (15) and culture dish (17) are separately positioned on working plate (11), after elevating lever (15) is fixedly installed on working plate (11)
End, the first fixator (12), the second fixator (13) and the 3rd fixator (14) are separately positioned on working plate (11) front end, train
Support ware (17) to be arranged between the first fixator (12), the second fixator (13) and the 3rd fixator (14), the first fixator
(12), the second fixator (13) is identical with the 3rd fixator (14) structure；
First fixator (12) includes the first fixed block (121), fixing bolt (122) and the second fixed block (123), and first fixes
Block (121) is identical with the second fixed block (123) structure, and is respectively fixedly disposed on working plate (11), the first fixed block
(121) and the second fixed block (123) upper end has the first internal thread hole respectively, and fixing bolt (122) is each passed through the first fixation
First internal thread hole of block (121) and the second fixed block (123), fixing bolt (122) are engaged with the first internal thread hole；
There is the first graduation mark (151) on elevating lever (15)；
Operating mechanism (2) includes fixed lowering or hoisting gear (21), screeding device (22) and drive device (23), fixed lowering or hoisting gear
(21) it is arranged on elevating lever (15), screeding device (22) and drive device (23) are separately positioned on fixed lowering or hoisting gear (21)
On,
Fixed lowering or hoisting gear (21) includes fixes sleeve (211), the first fixation lifting platform (212), the second fixation lifting platform (213)
With the first leading screw rotating shaft (16), the first fixation lifting platform (212) and the second fixation lifting platform (213) are separately positioned on fixes sleeve
(211) rear end, first, which fixes lifting platform (212) and second, fixes on lifting platform (213) respectively with the second coaxial internal thread
Hole, first leading screw rotating shaft (16) upper end have first-hand handle (161), and lower end has the first leading screw (162), the first leading screw rotating shaft
(16) fix lifting platform (212) and second through first to fix in the second internal thread hole of lifting platform (213), the first leading screw
(162) it is engaged with the second internal thread hole；
There is clamping screw (2111) in fixes sleeve (211)；
The structure on two sides of first fixation lifting platform (212) is identical, and front end has the first chute (2121), and upper end has the second chute
(2122), the second chute (2122) both sides have the second graduation mark (2123)；
Second fix lifting platform (213) structure on two sides it is identical, front end has the 3rd chute (2131), on the 3rd chute (2131)
With gear grooved,
Screeding device (22) includes the first slide bar (221), the second slide bar (222), connecting rod (223) and draws head (225), and first slides
Bar (221) and the second slide bar (222) are respectively fixedly disposed at connecting rod (223) upper/lower terminal, the first slide bar (221) both ends point
Not Ju You pointer head (226), connecting rod (223) lower end has jointing (224), draws a head (225) and is arranged on jointing
(224) lower end, the first slide bar (221) are arranged in the first chute (2121), and the second slide bar (222) is arranged on the 3rd chute
(2131) in, pointer head (226) is arranged on the second chute (2122)；
Drive device (23) includes the second rotating shaft (231) and driver (232), and the second rotating shaft (231) is arranged on driver (232)
It is interior, there is the second in command (233) and axostylus axostyle in the second rotating shaft (231), there is gear in driver (232), gear is arranged on axle
On bar, gear is mutually engaged with gear grooved；
Controlling organization (3) includes the first image pick-up device (31), the second image pick-up device (32) and display screen (33), the first image pick-up device (31),
Second image pick-up device (32) is separately positioned on working plate (11), and the first image pick-up device (31) and the second image pick-up device (32) are respectively with showing
Display screen (33) is connected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711180185.9A CN107699488A (en) | 2017-11-23 | 2017-11-23 | Tunable cell culture dish scoring devices |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711180185.9A CN107699488A (en) | 2017-11-23 | 2017-11-23 | Tunable cell culture dish scoring devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107699488A true CN107699488A (en) | 2018-02-16 |
Family
ID=61180687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711180185.9A Pending CN107699488A (en) | 2017-11-23 | 2017-11-23 | Tunable cell culture dish scoring devices |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107699488A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109055219A (en) * | 2018-09-17 | 2018-12-21 | 重庆医科大学附属儿童医院 | A kind of cell scar Healing Experiments device |
| CN109628281A (en) * | 2019-02-14 | 2019-04-16 | 严清园 | A kind of dedicated scoring devices of microbial culture dish |
| CN110551630A (en) * | 2019-09-24 | 2019-12-10 | 中南大学湘雅医院 | cell scratch cell and cell scratch operation method |
| CN110846400A (en) * | 2019-10-30 | 2020-02-28 | 吉林大学 | Human peripheral blood circulation FST mRNA detection kit and application thereof |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070105214A1 (en) * | 2005-11-09 | 2007-05-10 | Irm, Llc | Automated cellular assaying systems and related components and methods |
| CN101508954A (en) * | 2009-03-18 | 2009-08-19 | 南开大学 | Scuffing experimental device for cell migration research and high throughput medicament sifting motion |
| CN201689021U (en) * | 2010-02-05 | 2010-12-29 | 赵宏伟 | Micro-nanometer level in-situ nanometer indentation scratch test system |
| CN203728831U (en) * | 2014-03-19 | 2014-07-23 | 中南大学湘雅医院 | Cell scratch experimental device |
| CN105203363A (en) * | 2015-10-26 | 2015-12-30 | 安徽神剑新材料股份有限公司 | Automatic scratching device for corrosion resistance testing of coating |
| CN204964362U (en) * | 2015-08-17 | 2016-01-13 | 宁波键一电子信息技术有限公司 | Incasement cell culture network type intelligence formation of image analysis appearance alive |
| CN105296325A (en) * | 2015-09-01 | 2016-02-03 | 西安交通大学 | Cell scratch testing device |
| CN107132139A (en) * | 2017-05-08 | 2017-09-05 | 吉林大学 | Suspension type rotary quickly positions impression in situ/deepen arc cut test device |
| CN207498398U (en) * | 2017-11-23 | 2018-06-15 | 吉林大学 | Tunable cell culture dish scoring devices |
-
2017
- 2017-11-23 CN CN201711180185.9A patent/CN107699488A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070105214A1 (en) * | 2005-11-09 | 2007-05-10 | Irm, Llc | Automated cellular assaying systems and related components and methods |
| CN101508954A (en) * | 2009-03-18 | 2009-08-19 | 南开大学 | Scuffing experimental device for cell migration research and high throughput medicament sifting motion |
| CN201689021U (en) * | 2010-02-05 | 2010-12-29 | 赵宏伟 | Micro-nanometer level in-situ nanometer indentation scratch test system |
| CN203728831U (en) * | 2014-03-19 | 2014-07-23 | 中南大学湘雅医院 | Cell scratch experimental device |
| CN204964362U (en) * | 2015-08-17 | 2016-01-13 | 宁波键一电子信息技术有限公司 | Incasement cell culture network type intelligence formation of image analysis appearance alive |
| CN105296325A (en) * | 2015-09-01 | 2016-02-03 | 西安交通大学 | Cell scratch testing device |
| CN105203363A (en) * | 2015-10-26 | 2015-12-30 | 安徽神剑新材料股份有限公司 | Automatic scratching device for corrosion resistance testing of coating |
| CN107132139A (en) * | 2017-05-08 | 2017-09-05 | 吉林大学 | Suspension type rotary quickly positions impression in situ/deepen arc cut test device |
| CN207498398U (en) * | 2017-11-23 | 2018-06-15 | 吉林大学 | Tunable cell culture dish scoring devices |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109055219A (en) * | 2018-09-17 | 2018-12-21 | 重庆医科大学附属儿童医院 | A kind of cell scar Healing Experiments device |
| CN109628281A (en) * | 2019-02-14 | 2019-04-16 | 严清园 | A kind of dedicated scoring devices of microbial culture dish |
| CN110551630A (en) * | 2019-09-24 | 2019-12-10 | 中南大学湘雅医院 | cell scratch cell and cell scratch operation method |
| CN110846400A (en) * | 2019-10-30 | 2020-02-28 | 吉林大学 | Human peripheral blood circulation FST mRNA detection kit and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107699488A (en) | Tunable cell culture dish scoring devices | |
| US11412776B2 (en) | Smoking path simulation system based on robotic arm | |
| CN203519442U (en) | Vickers indentation hardness measurement system | |
| CN107045822B (en) | It demonstrates the physical teaching aid of natural frequency of object and compares the method for different metal intrinsic frequency | |
| CN207498398U (en) | Tunable cell culture dish scoring devices | |
| CN205910190U (en) | Rating of merit test device is kept apart to pitch isolating agent | |
| CN105338321A (en) | Image acquisition equipment and machine vision experiment platform comprising equipment | |
| DE212019000015U1 (en) | A device for measuring the flexible material type | |
| CN202583020U (en) | Durometer | |
| CN101629880B (en) | Horizontally push-type bidirectional sample preparation instrument | |
| CN109115685B (en) | Auxiliary positioning system for ultrathin section of electron microscope | |
| CN210427218U (en) | Quick marking device of tensile sample | |
| CN111982734A (en) | Rock wear resistance test device and test method | |
| CN104502064A (en) | Endoscope optical parameter detection apparatus | |
| CN209118593U (en) | A kind of convex lens imaging demonstration device | |
| CN213120450U (en) | Image detection equipment for glass mold | |
| CN207908278U (en) | Intercrystalline corrosion samples manual bending device | |
| CN207238042U (en) | A kind of water-bath | |
| CN207478626U (en) | A kind of new teaching use for laboratory demonstration console | |
| US12092614B2 (en) | Ultrasonic-resilience value testing apparatus for inorganic non-metal plate | |
| CN108717019A (en) | A kind of forcing press of test block temperature-controllable | |
| CN205382168U (en) | Medical microorganism is synthesized and inspects appearance | |
| CN211452588U (en) | Calibrating device for electronic balance | |
| CN205140924U (en) | Quick positioner of scanning electron microscope sample microdomain | |
| CN105300291B (en) | Seed morphology size visualizer and observation procedure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |