CN107694650A - Micro-fluidic chip real time humiture controls attachment device - Google Patents
Micro-fluidic chip real time humiture controls attachment device Download PDFInfo
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- CN107694650A CN107694650A CN201711023268.7A CN201711023268A CN107694650A CN 107694650 A CN107694650 A CN 107694650A CN 201711023268 A CN201711023268 A CN 201711023268A CN 107694650 A CN107694650 A CN 107694650A
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- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 21
- 238000000576 coating method Methods 0.000 claims description 12
- 238000001816 cooling Methods 0.000 claims description 10
- 238000007791 dehumidification Methods 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 9
- 230000003287 optical effect Effects 0.000 claims description 5
- 238000002347 injection Methods 0.000 claims description 4
- 239000007924 injection Substances 0.000 claims description 4
- 238000002474 experimental method Methods 0.000 abstract description 10
- 238000001514 detection method Methods 0.000 abstract description 4
- 238000012544 monitoring process Methods 0.000 abstract description 4
- 210000000056 organ Anatomy 0.000 abstract description 3
- 210000004027 cell Anatomy 0.000 description 11
- 238000000034 method Methods 0.000 description 10
- 238000009413 insulation Methods 0.000 description 8
- 239000011248 coating agent Substances 0.000 description 7
- 238000000926 separation method Methods 0.000 description 7
- 239000000523 sample Substances 0.000 description 5
- 239000002775 capsule Substances 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000003851 biochemical process Effects 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 239000013536 elastomeric material Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000006641 stabilisation Effects 0.000 description 3
- 238000011105 stabilization Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 238000011217 control strategy Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000013152 interventional procedure Methods 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 238000009422 external insulation Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000007885 magnetic separation Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D27/00—Simultaneous control of variables covered by two or more of main groups G05D1/00 - G05D25/00
- G05D27/02—Simultaneous control of variables covered by two or more of main groups G05D1/00 - G05D25/00 characterised by the use of electric means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Automation & Control Theory (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention belongs to the analysis technical field such as the bionical reconstruct micro-fluidic chip with microenvironment of organ, Cell Biology Experiment, single cell analysis and detection, further chambers component, Heat insulated conduit and temperature humidity control device on a kind of control of micro-fluidic chip real time humiture attachment device, including piece especially set out；Described upper further chambers component includes further chambers, recyclegas entrance and recyclegas outlet；Recyclegas entrance and the recyclegas outlet is arranged in further chambers, and recyclegas entrance and recyclegas outlet are tightly connected by a Heat insulated conduit with temperature humidity control device respectively.The present invention accurately controls the epidemic disaster parameter of air chamber by temperature humidity control device, you can realizes the dynamic monitoring and control of the temperature, humidity of micro-fluidic chip.
Description
Technical field
The invention belongs to the bionical reconstruct micro-fluidic chip with microenvironment of organ, Cell Biology Experiment, single cell analysis with
The analysis technical fields such as detection, micro-fluidic chip real time humiture especially set out control attachment device.
Background technology
Analytical technology of the microflow control technique as brand-new microcosmic point, obtain the weight of nearly all biochemical worker of medical treatment
Depending on the common concern of industry and wide has been obtained in the field such as medical treatment, health, physical chemistry, bio-pharmaceuticals and genetic engineering at present
General application.Such as in biomedical sector, active somatic cell and tissue cultures, organ it is bionical with microenvironment reconstruct, single cell analysis with
The experiment such as detection, it is desirable to which whole process is strictly simulated true in nature biotechnology body（It is micro-）Physiological environment, show physics bar
On part, it is desirable to which temperature, the humidity even parameter such as gas componant of experimentation must accurately be controlled in desired value, and whole mistake
Journey must not be interrupted artificially.For emerging micro-current control biochemical analytical technology, for reach epidemic disaster control in real time this it is harsh will
Ask, it has to use or microfluidic system complete machine is placed in biochemical cultivation case, or micro-fluidic chip is periodically moved in and out training
Support and compromise is waited in case, both added system cost and volume, and cause result of the test because of coming and go for experimental condition
Inaccuracy, do not know.The epidemic disaster real-time online control of micro-fluidic chip can be realized, and does not influence whole experimental implementation
Fully integrated, compact-sized fexible unit have become and be badly in need of in the industry, but be not reported all the time, also there are no it is related specially
Profit application.
The content of the invention
For above-mentioned present situation, the present invention proposes a kind of brand-new micro-fluidic chip humiture and controls attachment device in real time,
The modular construction using separation is characterized in, compact-sized further chambers are individually airtight to be added on chip, by following
Ring conduit is connected with temperature, humidity main control unit, realizes the temperature of micro-fluidic chip, the stabilization of humidity parameter, accurately and fast controls
Make, epidemic disaster environment simulates the purpose of the biochemical process of setting completely in real-time on guarantee piece.
To reach above-mentioned purpose, the technical scheme is that micro-fluidic chip real time humiture control attachment device includes
Further chambers component, Heat insulated conduit and temperature humidity control device on piece；Described upper further chambers component include further chambers,
Recyclegas entrance and recyclegas outlet；Recyclegas entrance and the recyclegas outlet is arranged in further chambers,
Recyclegas entrance and recyclegas outlet are tightly connected by a Heat insulated conduit with temperature humidity control device respectively.
The further chambers component being placed on micro-fluidic chip separates arrangement with temperature humidity control device, compact-sized；
Pass through Heat insulated conduit and temperature humidity control device（Main control unit）It is tightly connected, under forced gas circulative metabolism, passes through
Forced circulation is implemented to the gas medium for being adapted to cell and tissue culture so that epidemic disaster and temperature humidity control in further chambers
Device processed（Main control unit）Dynamic is consistent in real time；Pass through temperature humidity control device（Main control unit）Accurate control air chamber
Epidemic disaster parameter, you can realize the dynamic monitoring and control of the temperature, humidity of micro-fluidic chip.
Further, further chambers include further chambers pedestal and heat-insulated chamber, further chambers pedestal and chip fixed base
Seat is detachably connected, and sets heat-insulated chamber on further chambers pedestal, recyclegas entrance and recyclegas outlet be arranged at every
On hot chamber.
Further, further chambers pedestal is connected by fixing bolt with chip fixed pedestal.
Further, the bottom of further chambers sets elastic seal ring along micro-fluidic chip microlayer model transport path periphery,
Elastic seal ring is pressed on chip surface, is tightly connected.
The further chambers top being placed on micro-fluidic chip is connected using simple bolt with chip base, by elasticity
Packing ring and micro-fluidic chip air-tight fit, simple, quick, reliable, fast and easy changes new film.It is applied to live for micro-fluidic chip
The medical science biochemistry such as cell, and realize that temperature on piece, the control of humidity dynamic realtime provide really simple efficient solutions.
Scientific research personnel is really taken leave of cumbersome, error and uncertainty, be advantageous to simplify experimentation, improve experiment success rate.
Further, heat-insulated chamber uses Double-layered transparent shell structure.
The further chambers being placed on micro-fluidic chip use Double-layered transparent shell structure, insulation, reduce environment temperature
The disturbing influence that degree change may be brought；Increase chamber room brilliancy, be easy to observe, convenient experiment.
Further, heat-insulated chamber sidewall sets intervention window.
The intervention window on the further chambers top being placed on micro-fluidic chip, it is made up of the elastomeric material of excellent thermal insulation soft
Property chamber capsule, is external mechanical devices, such as magnetic probe sorting mechanism, there is provided a range of three-dimensional manipulating space.
Further, the upper cover design of heat-insulated chamber is observation window, and heat-insulated optical channel, mirror are formed using double layer lens
Piece has anti-fogging coatings or coating structure.
The double layer lens on the further chambers top being placed on micro-fluidic chip（Optical observation window）, with double optics lens
Form, it is airtight heat-insulated；Eyeglass passes through antifogging coating or coating film treatment, it is ensured that fogging, convenience are not grasped under the conditions of complicated epidemic disaster
Make personnel manually to observe, ensure that camera system is reliably clearly absorbed, records experimentation, observed under large scale visual condition
The motion process of drop, data basis is provided for follow-up rear experimental analysis.
Further, temperature humidity control device includes dynamic mixed air vessel, humidification, dehumidification module, heating, cooling mould
Block, temperature and relative humidity and driving fan；It is dynamic mixed air vessel and humidification, dehumidification module, heating, cooling module and temperature, wet
Degree sensor is connected respectively, and driving fan is set in dynamic mixed air vessel；
Temperature and relative humidity is used to measure the epidemic disaster parameter in dynamic mixed air vessel in real time, judges that they are inclined with setting value
Difference；
Wet, dehumidification module and heating, cooling module are used to be controlled in real time according to deviation, it is ensured that warm, wet in dynamic mixed air vessel
Parameter stability is spent in setting value；
The gas injection further chambers that driving fan is used in dynamic mixed air vessel.
Beneficial effects of the present invention：Using the modular structure of separation, it is compact-sized, minimize, be responsible for chip circumference seek
Produce the further chambers with ideal temperature, humidity environment.The warm, wet of trapping room is accurately controlled by temperature humidity control device
Spend parameter, you can realize the dynamic monitoring and control of the temperature, humidity of micro-fluidic chip.
The overall description of the present invention：A kind of micro-fluidic chip epidemic disaster controls attachment device in real time, using the module of separation
Structure, it is compact-sized, be responsible for building the further chambers with ideal temperature, humidity environment in chip circumference, individually it is added to
On chip, it is connected via circulation airway tube with the temperature that separates, humidity main control unit, forms complete epidemic disaster and control in real time
System processed；Further chambers are double-decked insulation, to reduce temperature interference of the environment to chip；Observation is provided with above further chambers
Window, its eyeglass use anti-fogging coatings plated film, high humility, high temperature difference application conditions under can still keep clear, for operation
Member or camera system provide reliable observation window.Further chambers are provided with air hermetic mechanically actuated bar interface, are available for such as magnetic separation
The mechanism interventional procedures such as probe.The temperature of separation, humidity main control unit be integrated with temperature-humidity sensor, intelligent controller and
The module such as heat, freeze, humidifying, drying, by with reference to advanced control algorithm, making its mixed air vessel, and the temperature of further chambers
Degree, humidity are accurately controlled in desired value, and then realize the temperature of micro-fluidic chip, the stabilization of humidity parameter, accurately and fast control
Make, the accurate simulation of epidemic disaster environment approaches the biochemical process of setting on guarantee piece.The present invention relates to a kind of micro-fluidic chip
The attachment device that epidemic disaster controls in real time, the device are tested to chip for living cells and fabric study and detection mesophytization
The specific needs that temperature, humidity and suitable cell are set with gas microenvironment, using superposing type further chambers and epidemic disaster on piece
The method of main control unit separation, the two it will be connected above by the conduit with external insulation；Further chambers are placed directly within micro-fluidic
On chip, the elastic seal ring of its bottom margin and micro-fluidic chip are carried out and are tightly connected, via especially being set on chip pole plate
The micropore put carries out passing wet, heat transfer, ensures that the epidemic disaster environment of microlayer model in chip is consistent with further chambers；Additional chamber
Room is provided with air inlet, exhaust port, and carrying out gas circulation with main control unit by heat-insulating hose exchanges；Further chambers outer wall is using double
The heat-insulated antifog transparent configuration of layer, top are the optical observation window of special plated film double layer lens composition, reduce environment temperature to chamber
Interior influence, avoids fogging, is easy to obtain clear experiment image visually or via light microscope and other video acquisition devices；
Separately positioned epidemic disaster main control unit, the gas-powered fan set in it is by the suitable cell of specific epidemic disaster with organizing
The gas medium injection further chambers of culture, forced circulation, make the further chambers on chip（Namely micro-fluidic chip）With master
Microenvironment epidemic disaster in control unit is consistent；Humidification, dehumidifying and temperature control modules are provided with main control unit, and
Related temperature and relative humidity, control of temperature and humidity loop is formed, the steady of epidemic disaster parameter is realized with reference to Advanced Control Strategies
Determine, accurately and fast control.This method realizes the gas to array experiment environment temperature, humidity and suitable cell and tissue culture
Body component accurately control in real time, incessantly, eliminates and whole micro-fluidic chip experimental provision is placed in incubator, or
Micro-fluidic chip is moved into, removes incubator and it is frequently inconvenient in the operation such as interrupt experiments the drawbacks of, eliminate therefore and make
Into uncertainty and unstability, avoid the overall too fat to move volume of equipment, simplify experimentation, keeping micro-fluidic core
On the premise of piece micromation advantage, the accuracy and the probability of success of experiment are improved.
Brief description of the drawings
Fig. 1 is further chambers modular construction explosive view on the piece of the present invention；
Fig. 2 is the structural representation of the present invention；
In figure：1st, Heat insulated conduit, 2, temperature humidity control device, 3, recyclegas entrance, 4, recyclegas outlet, 5, additional chamber
Room pedestal, 6, heat-insulated chamber, 7, chip fixed pedestal, 8, fixing bolt, 9, micro-fluidic chip, 10, elastic seal ring, 11, be situated between
Enter window, 12, observation window.
Embodiment
Embodiment 1
Micro-fluidic chip real time humiture control attachment device includes further chambers component, Heat insulated conduit 1 and temperature humidity on piece
Control device 2；Described upper further chambers component includes further chambers, recyclegas entrance 3 and recyclegas outlet 4；It is described
Recyclegas entrance 3 and recyclegas outlet 4 are arranged in further chambers, and recyclegas entrance 3 and recyclegas export 4 points
It is not tightly connected by a Heat insulated conduit 1 with temperature humidity control device 2.
The further chambers component being placed on micro-fluidic chip separates arrangement with temperature humidity control device, compact-sized；
Pass through Heat insulated conduit and temperature humidity control device（Main control unit）It is tightly connected, under forced gas circulative metabolism, passes through
Forced circulation is implemented to the gas medium for being adapted to cell and tissue culture so that epidemic disaster and temperature humidity control in further chambers
Device processed（Main control unit）Dynamic is consistent in real time；Pass through temperature humidity control device（Main control unit）Accurate control air chamber
Epidemic disaster parameter, you can realize the dynamic monitoring and control of the temperature, humidity of micro-fluidic chip.
Further, the further chambers include further chambers pedestal 5 and heat-insulated chamber 6, the further chambers pedestal 5 with
Chip fixed pedestal 7 is detachably connected, and heat-insulated chamber 6, the recyclegas entrance 3 and circulation are set on further chambers pedestal 5
Gas vent 4 is arranged on heat-insulated chamber 6.
Further, further chambers pedestal 5 is connected by fixing bolt 8 with chip fixed pedestal 7.
Further, the bottom of the further chambers sets elasticity close along the microlayer model transport path of micro-fluidic chip 9 periphery
Seal 10, elastic seal ring 10 are pressed on chip surface, are tightly connected.
The further chambers top being placed on micro-fluidic chip 9 is connected using simple bolt with chip base, by bullet
Property sealing ring 10 and the air-tight fit of micro-fluidic chip 9, simple, quick, reliable, fast and easy changes new film.For micro-fluidic chip 9
Applied to the medical science biochemistry such as living cells, and it is really simple efficient to realize that temperature on piece, the control of humidity dynamic realtime provide
Solution.Scientific research personnel is really taken leave of cumbersome, error and uncertainty, be advantageous to simplify experimentation, improve real
Test success rate.
Further, the heat-insulated chamber 6 uses Double-layered transparent shell structure.
The further chambers being placed on micro-fluidic chip 9 use Double-layered transparent shell structure, insulation, reduce environment temperature
The disturbing influence that degree change may be brought；Increase chamber room brilliancy, be easy to observe, convenient experiment, isolate extraneous epidemic disaster shadow
Ring, prevent fogging, be easy to observe micro-fluidic chip state.
Further, the heat-insulated side wall of chamber 6 sets intervention window 11.
The intervention window 11 on the further chambers top being placed on micro-fluidic chip 9, by the elastomeric material system of excellent thermal insulation
It is external mechanical devices into soft chamber capsule, sorts probe for magnetic probe or other mechanisms carry out interventional procedure, such as magnetic probe point
Mechanism is selected, is sealed between motion arm and chamber by flexible bellows, there is provided a range of three-dimensional manipulating space.
Further, the upper cover design of heat-insulated chamber 6 is observation window 12, and forming heat-insulated optics using double layer lens leads to
Road, eyeglass have anti-fogging coatings or coating structure, for operating personnel visually or microscopic and video signal collective.
The lens on the further chambers top being placed on micro-fluidic chip 9（Optical observation window）, with double optics lens structure
Into airtight heat-insulated；Eyeglass passes through antifogging coating or coating film treatment, it is ensured that fogging, convenience do not operate under the conditions of complicated epidemic disaster
Personnel manually observe, and ensure that camera system is reliably clearly absorbed, records experimentation, liquid is observed under large scale visual condition
The motion process of drop, data basis is provided for follow-up rear experimental analysis.
Further, temperature humidity control device 2 includes dynamic mixed air vessel, humidification, dehumidification module, heating, cooling mould
Block, temperature and relative humidity and driving fan；The dynamic mixed air vessel and humidification, dehumidification module, heating, cooling module and
Temperature and relative humidity is connected respectively, and driving fan is set in dynamic mixed air vessel；
Temperature and relative humidity is used to measure the epidemic disaster parameter in dynamic mixed air vessel in real time, judges that they are inclined with setting value
Difference；
Wet, dehumidification module and heating, cooling module are used to be controlled in real time according to deviation, it is ensured that warm, wet in dynamic mixed air vessel
Parameter stability is spent in setting value；
The gas injection further chambers that driving fan is used in dynamic mixed air vessel.
Separately positioned epidemic disaster main control unit is provided with dynamic mixed air vessel, and periphery is provided with humidification, dehumidifying and risen
Temperature, cooling module, and related temperature and relative humidity, the epidemic disaster parameter in mixed air vessel are measured in real time, according to them
And the deviation of setting value, the real-time control of epidemic disaster parameter is realized by Advanced Control Strategies, it is ensured that it is stable at setting value；
The gas for meeting epidemic disaster requirement in mixed air vessel is injected further chambers by driving fan, carries out forced circulation, it is ensured that piece epicoele
Room（Namely micro-fluidic chip）It is internal consistent with the epidemic disaster inside main control unit and gas componant.
Embodiment 2
It is an object of the invention to provide a kind of brand-new micro-fluidic chip epidemic disaster to control attachment device in real time, is characterized in adopting
With the modular construction of separation, compact-sized further chambers are individually airtight to be added on chip, passes through Heat insulated conduit 1（Follow
Ring conduit）It is connected with temperature humidity control device 2, realizes the temperature of micro-fluidic chip 9, the stabilization of humidity parameter, accurately and fast
Control, epidemic disaster environment simulates the biochemical process of setting completely in real-time on guarantee piece.
The present invention provides a kind of brand-new micro-fluidic chip epidemic disaster and controls attachment device, compact further chambers in real time
Including double-deck anti-fog lens group, heat-insulated chamber 6 and further chambers pedestal 5, individually it is added on micro-fluidic chip 9, by solid
Determine bolt 8 to be connected with chip fixed pedestal 7, compress elastic seal ring 10, and micro-fluidic chip 9 is airtight is connected.Further chambers are
Double-decked insulation is to improve environment resistant temperature, humidity interference performance.Heat insulated conduit 1（Circulation conduit）Recyclegas is connected to enter
Mouth 3 and recyclegas outlet 4, and the temperature humidity control device 2 with separating is connected.
The present invention provides a kind of brand-new micro-fluidic chip epidemic disaster and controls attachment device in real time, the further chambers
Observation window 12 is double-layer lens structure to increase heat-insulating capability；Eyeglass uses anti-fogging coatings or antifog coating film treatment, prevents
Fogging, ensure the definition and light penetrability of window under the conditions of complicated epidemic disaster.
The present invention provides a kind of brand-new micro-fluidic chip epidemic disaster and controls attachment device in real time, the further chambers
Soft chamber capsule is made by the elastomeric material of excellent thermal insulation in intervention window 11, and airtight is fixed on the transparent heat-insulated chamber 6 of double thermal insulation
Side wall；External mechanical action bars can be intervened via chamber capsule side, and with the airtight locking of bayonet socket.
The present invention provides a kind of brand-new micro-fluidic chip epidemic disaster and controls attachment device in real time, the further chambers
Side wall is double transparent material, improves heat-insulating capability, increases light transmission capacity to facilitate observation and image capture.
The present invention provides a kind of brand-new micro-fluidic chip epidemic disaster and controls attachment device, the further chambers base in real time
Recyclegas entrance 3 and the recyclegas outlet 4 of seat 5 is fast gas joint, convenient to be connected with Heat insulated conduit 1；Recyclegas
Gateway connects with further chambers inner chamber, forms gas circulation channel；The fan for being placed in the temperature humidity control device 2 of separation is strong
System driving, which is controlled in, it is expected that the gas of epidemic disaster state enters further chambers, by diabatic process, makes and further chambers one
Micro-fluidic chip reach identical epidemic disaster, realize it is stable, accurately and fast control.
Applicant states that the present invention describes the feature and method of the present invention, but not office of the invention by examples detailed above
It is limited to above-mentioned detailed features and method detailed, that is, does not mean that the present invention has to rely on above-mentioned detailed features and method detailed
It can implement.Any improvement in the present invention, the equivalence replacement of component and adding, being specific square for auxiliary element are selected to the present invention
Selection of formula etc., within the scope of all falling within protection scope of the present invention and disclosing.
Claims (8)
1. micro-fluidic chip real time humiture controls attachment device, it is characterised in that：Including further chambers component on piece, heat-insulated lead
Pipe and temperature humidity control device；Described upper further chambers component includes further chambers, recyclegas entrance and recyclegas
Outlet；Recyclegas entrance and the recyclegas outlet is arranged in further chambers, recyclegas entrance and recyclegas
Outlet is tightly connected by a Heat insulated conduit with temperature humidity control device respectively.
2. micro-fluidic chip real time humiture according to claim 1 controls attachment device, it is characterised in that：It is described additional
Chamber includes further chambers pedestal and heat-insulated chamber, and the further chambers pedestal is detachably connected with chip fixed pedestal, adds
Heat-insulated chamber is set on chamber pedestal, and recyclegas entrance and the recyclegas outlet is arranged on heat-insulated chamber.
3. micro-fluidic chip real time humiture according to claim 2 controls attachment device, it is characterised in that：Further chambers
Pedestal is connected by fixing bolt with chip fixed pedestal.
4. micro-fluidic chip real time humiture according to claim 2 controls attachment device, it is characterised in that：It is described additional
The bottom of chamber sets elastic seal ring along micro-fluidic chip microlayer model transport path periphery, and elastic seal ring is pressed on chip list
Face, it is tightly connected.
5. micro-fluidic chip real time humiture according to claim 2 controls attachment device, it is characterised in that：It is described heat-insulated
Chamber uses Double-layered transparent shell structure.
6. micro-fluidic chip real time humiture according to claim 1 controls attachment device, it is characterised in that：It is described additional
The upper lid of chamber is observation window, forms heat-insulated optical channel using double layer lens, eyeglass has anti-fogging coatings or plated film knot
Structure.
7. micro-fluidic chip real time humiture according to claim 1 controls attachment device, it is characterised in that：It is described additional
Chamber sidewall sets intervention window.
8. micro-fluidic chip real time humiture according to claim 1 controls attachment device, it is characterised in that：The temperature
Humidity conditioner includes dynamic mixed air vessel, humidification, dehumidification module, heating, cooling module, temperature and relative humidity and driving
Fan；The dynamic mixed air vessel and humidification, dehumidification module, heating, cooling module and temperature and relative humidity connect respectively,
Driving fan is set in dynamic mixed air vessel；
Temperature and relative humidity is used to measure the epidemic disaster parameter in dynamic mixed air vessel in real time, judges that they are inclined with setting value
Difference；
Wet, dehumidification module and heating, cooling module are used to be controlled in real time according to deviation, it is ensured that warm, wet in dynamic mixed air vessel
Parameter stability is spent in setting value；
The gas injection further chambers that driving fan is used in dynamic mixed air vessel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711023268.7A CN107694650A (en) | 2017-10-27 | 2017-10-27 | Micro-fluidic chip real time humiture controls attachment device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711023268.7A CN107694650A (en) | 2017-10-27 | 2017-10-27 | Micro-fluidic chip real time humiture controls attachment device |
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| Publication Number | Publication Date |
|---|---|
| CN107694650A true CN107694650A (en) | 2018-02-16 |
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| CN201711023268.7A Pending CN107694650A (en) | 2017-10-27 | 2017-10-27 | Micro-fluidic chip real time humiture controls attachment device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023159910A1 (en) * | 2022-02-23 | 2023-08-31 | 常州先趋医疗科技有限公司 | Temperature measurement apparatus and method in lamp |
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