CN107693616A - A kind of composition of preventing diaper dermatitis and its preparation method and application - Google Patents
A kind of composition of preventing diaper dermatitis and its preparation method and application Download PDFInfo
- Publication number
- CN107693616A CN107693616A CN201710973189.6A CN201710973189A CN107693616A CN 107693616 A CN107693616 A CN 107693616A CN 201710973189 A CN201710973189 A CN 201710973189A CN 107693616 A CN107693616 A CN 107693616A
- Authority
- CN
- China
- Prior art keywords
- parts
- composition
- diaper dermatitis
- preventing diaper
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/12—Magnesium silicate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of composition of preventing diaper dermatitis, it is made from the following raw materials in parts by weight：10 28 parts of sucrose octasulfate sodium, 5 10 parts of bisabolol, 20 40 parts of solvent, 15 parts of solubilizer, 50 100 parts of deionized water, 10 20 parts of Chinese medical extract, the Chinese medical extract is made from the following raw materials in parts by weight：39 parts of the root of kudzu vine, 39 parts of the coptis, 39 parts of golden cypress, 4 10 parts of radix glycyrrhizae, 6 10 parts of indigo naturalis, 10 20 parts of honeysuckle, 48 parts of myrrh, 4 10 parts of the root of Dahurain angelica, 59 parts of adenosma indianum, 15 parts of Radix Angelicae Sinensis, 6 10 parts of talcum.The composition of described preventing diaper dermatitis is preparing the application of paper diaper surface layer non-woven cloth.The composition of the preventing diaper dermatitis is added in conventional fibre spinning oil, or for non-woven cloth non-woven cloth final finishing.The present invention suppresses the stimulation of enzymes activity, control fecal enzymes allergen to skin, block allergy, addition Chinese medicine preparation has clearing heat and promoting diuresis, antimicrobial antiphlogistic, the effectiveness of wind-dispelling removing toxic substances, at the same can long skin, moist color, can also avoid the formation of scar.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, specifically a kind of composition of preventing diaper dermatitis and preparation method thereof and should
With.
Background technology
Diaper rash is to occur wrapping up in a kind of dermal inflammatory lesion at diaper position, the also referred to as red stern of baby, shows as buttocks
Rubefaction with diaper contact area, swell, or even occur festering, ulcer and infection, slightly slight external force or friction are just
Damage can be caused.Diaper rash is embodied in erythema, papule.Diaper rash is also known as " diaper dermatitis ", " ammonia dermatitis ", is one
The non-infectious scytitis of kind, is classified as " contact dermatitis ", " physical dermatitis ", " allergy dermatitis " in clinical medicine
(W allergic reaction types) category.On the etiology and pathology of diaper rash, medical field there is no clearly come to a conclusion so far, it is considered that be with
The result that lower combined factors play a role:(1) local humidity is too big:Especially, in the lasting permeability of paper diaper surface material
In the case that the poor and amount of bleeding back is larger, urine is easily stayed in surface layer storage, causes skin overly hydrated, stratum corneum barrier function drop
It is low, show as the sensitiveness enhancing to pessimal stimulation.(2) it is local ventilative bad:Further limit the volatilization of moisture, and can between
Connect the generation for promoting allergy.(3) allergic effect primary stimuli.The allergen includes:1. free ammonia:Urea in urine is in bacterium
In the presence of urine solution enzyme, ammonium hydroxide is decomposed into, raises the pH value of urine, when pH is more than 7.0, easily discharge free property
Ammonia；2. fecal enzymes:Medical field current research result shows in recent years, and (especially dyspeptic infant faeces) contain in excrement
All kinds of protein lyases and fat splitting enzyme, be the important allergen for causing diaper dermatitis；It is worth noting that, in local envelope
Close, in the environment of high humility, especially high ph-values, the activity of fecal enzymes is remarkably reinforced；3. microorganism:Bacterium or fungi and its generation
Thank to product.
The present invention is according to diaper rash pathogenesis, especially for various allergen stimulus, there is provided one kind is applied non-
The composition with preventing diaper dermatitis function in woven cloths, the non-woven cloth are mainly used in the face of disposable paper diaper
Layer.
The content of the invention
It is an object of the invention to provide a kind of composition of preventing diaper dermatitis and its preparation method and application, with solution
State the problem of being proposed in background technology.
To achieve the above object, the present invention provides following technical scheme：
A kind of composition of preventing diaper dermatitis, is made from the following raw materials in parts by weight：Sucrose octasulfate sodium 10-28 parts,
Bisabolol 5-10 parts, solvent 20-40 parts, solubilizer 1-5 parts, deionized water 50-100 parts, Chinese medical extract 10-20 parts, institute
Chinese medical extract is stated to be made from the following raw materials in parts by weight：Root of kudzu vine 3-9 parts, coptis 3-9 parts, golden cypress 3-9 parts, radix glycyrrhizae 4-10 parts,
Indigo naturalis 6-10 parts, honeysuckle 10-20 parts, myrrh 4-8 parts, root of Dahurain angelica 4-10 parts, adenosma indianum 5-9 parts, Radix Angelicae Sinensis 1-5 parts, talcum 6-10
Part.
As the further scheme of the present invention：It is made from the following raw materials in parts by weight：19 parts of sucrose octasulfate sodium, red do not have
7.5 parts of medicine alcohol, 30 parts of solvent, 3 parts of solubilizer, 75 parts of deionized water, 15 parts of Chinese medical extract.
As further scheme of the invention：The Chinese medical extract is made from the following raw materials in parts by weight：The root of kudzu vine 6
Part, 6 parts of the coptis, 6 parts of golden cypress, 7 parts of radix glycyrrhizae, 8 parts of indigo naturalis, 15 parts of honeysuckle, 6 parts of myrrh, 7 parts of the root of Dahurain angelica, 7 parts of adenosma indianum, Radix Angelicae Sinensis 3
Part, 8 parts of talcum.
As further scheme of the invention：The solubilizer is ethoxylated dodecyl alcohol -9.
As further scheme of the invention：The solvent is pentanediol.
As further scheme of the invention：The preparation method of the composition of described preventing diaper dermatitis, including it is following
Step：
(1) Chinese medical extract is prepared：Chinese medicine material is weighed by the important number, is broken to 30-50 mesh, adds Chinese medicine 5-
The water of 10 times of part by weight, boils 20-30min by intense fire, uses slow fire instead and decocts, and the dregs of a decoction are filtered off after infusion 30-40min, and decoction is cold
But it is standby to room temperature；
(2) sucrose octasulfate sodium, bisabolol, solvent, solubilizer, deionized water are weighed by the important number, first
Deionized water is heated to 60-80 DEG C, then adds sucrose octasulfate sodium, bisabolol, solvent and solubilizer, stirring makes to fill
After dividing dissolving, traditional Chinese medicine liquid is added, stirs, is cooled to normal temperature,.
As further scheme of the invention：Paper diaper surface layer is non-to be knitted the composition of described preventing diaper dermatitis preparing
Make the application of cloth.
As further scheme of the invention：The composition of the preventing diaper dermatitis adds to conventional fibre spinning oil
In.
As further scheme of the invention：The composition of the preventing diaper dermatitis is used for non-woven cloth final finishing, first
The composition of the preventing diaper dermatitis is diluted to 2wt% concentration with deionized water, then urinated with the prevention after the dilution
The composition of cloth rash arranges to non-woven cloth.
Ethoxylated dodecyl alcohol -9：As the nonionic surface active agent of middle low-carbon chain structure, non-woven cloth is assigned
Rapid osmotic performance, there is solubilization.
Sucrose octasulfate sodium:It has the special role of protease inhibition, lipase active, has been successfully applied to face
Bed, clinically it is the oral drug for preparing treatment gastric ulcer.The present invention uses it for the group of the preventing diaper dermatitis
Compound, it is taken to suppress the effect of enzymes activity, so as to control stimulation of the fecal enzymes allergen to skin.
Bisabolol:Acted on corticoid sample, antihistamine, suppress the generation of T lymphocytes, block allergy hair
It is raw.
Pentanediol:There is solubilization to other components in the composition of the preventing diaper dermatitis, contribute to described pre-
The quick preparation of the composition of anti-diaper rash and conveniently apply.Meanwhile pentanediol has gentle antibacterial functions concurrently, pentanediol passes through
Promote the protein coagulation of mushroom microorganism and antibacterial.
The root of kudzu vine:Expelling pathogenic factors from muscles and skin is brought down a fever, and promoting eruption, is promoted the production of body fluid to quench thirst, Shengyang Zhixie.Generated heat for exterior syndrome, stiff nape and back, measles without adequate eruption,
Pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.
The coptis:Heat-clearing, cool blood, eliminating dampness.Infantile malnutrition due to digestive disturbances or intestinalparasites is controlled, disease is shied, rush down dysentery, the hot hectic fever due to yin of labor, spontaneous perspiration, night sweat, spits blood, pinkeye, hemorrhoid
Repeatly, sore.
Golden cypress:There is a heat-clearing and damp-drying drug, purging intense heat, except steaming, the effect of detoxification sore treatment.For damp-heat dysentery, yellow subcutaneous ulcer urine is red, with lower the moon
Itch, puckery pain of heat gonorrhea, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema wet sore.
Radix glycyrrhizae:With invigorating the spleen and benefiting qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, the effect of coordinating the drug actions of a prescription.It is usually used in spleen
Stomach is weak, lassitude hypodynamia, palpitation, coughing with a lot of sputum, institute's abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviates drug toxicity, strong
Property.
Indigo naturalis：Nature and flavor are salty-cold, Return liver, lung, stomach.There is clearing heat and detoxicating, cool blood to dissipate the effect such as swollen, clearing liver-fire, arresting convulsion.It is main
Control warm disease excess heat, macula, spit blood, spitting of blood, pharyngalgia, aphtha, pediatric epilepsy scared, sore swells, erysipelas, eczema, Cuo carbuncles, mumps, snakeworm stings
Wound etc..Modern pharmacological research shows that indigo naturalis has antitumor, antibacterium and dermatophyte, enhancing is immune, treats ulcer, liver protection etc.
Effect.
Talcum:Inducing diuresis for treating strangurtia, clearing away summerheat, clearing damp sore.It is damp and hot for heat gonorrhea, urolithiasis, the puckery pain of urine heat, summer-heat and damp polydipsia
Watery diarrhea；Control eczema, wet sore, son of itching outside.
Honeysuckle:Can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile diseases, such as body heat, dermexanthesis, send out spot, heat toxin
The diseases such as sore carbuncle, abscess of throat.
Adenosma indianum：It is pungent, bitter, temperature.Major function wind-expelling pain-stopping, eliminating stasis to subdue swelling, detoxifying and relieving itching.For polio initial stage,
Suffer from cold stomachache, treating rheumatic ostealgia.Traumatic injury is controlled in external application, swelling and pain, carbuncle furuncle poison, wasp sting, eczema, nettle rash.
Myrrh：Enter liver, spleen, the heart, kidney channel.Hair growing, nti-freckle disappear trace, and softening hard masses remove knurl, and except tinea is more created, permanent tooth be good for gum, solution
Poison etc..Alopecia capillary is controlled, black spot bruise, flat wart, various eczemas, gum is rotten to the corn, and poisonous insect stings wound etc..
The root of Dahurain angelica：Expel pathogenic wind from the body surface, eliminating cold to stop pain, the sensible, detumescence and apocenosis of dehumidifying.Microcirculation in human body can be improved, promote skin new
Old metabolism, pigment excess accumulation in the tissue is eliminated, remove facial colour spot scar, treatment skin blister wound mange etc..《Legendary god of farming's book on Chinese herbal medicine
Through》Point out the root of Dahurain angelica：" long skin.Moist color, can make face fat.”
Radix Angelicae Sinensis：Nature and flavor are sweet, pungent, warm, cure mainly all cards of the deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, and abdominal mass knot gathers, uterine bleeding, the cold of insufficiency type
Stomachache, Impotence numbness, numbness, intestines are dry and shit is difficult, weight, ulcer sores, injury from falling down after dysentery characterized by blood in the stool.External application can accelerate wound healing, make
Contrafluxion, leucocyte and fiber infiltration, newborn epithelium regeneration, there is hemostasis to local organization and strengthen peripheral circulation effect.
Compared with prior art, the beneficial effects of the invention are as follows：The sucrose octasulfate sodium of the composition addition of the present invention
And bisabolol, suppress the stimulation of enzymes activity, control fecal enzymes allergen to skin, block allergy, in addition, logical
Preventing diaper dermatitis composition prepared by addition Chinese medicine preparation is crossed, there is clearing heat and promoting diuresis, antimicrobial antiphlogistic, the effectiveness of wind-dispelling removing toxic substances, together
When can long skin, moist color, selected medicine is gentle, and skin that will not be tender and lovely to infant produces stimulation, can also avoid
The formation of scar.
Embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.Based in the present invention
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all
Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of composition of preventing diaper dermatitis, it is made from the following raw materials in parts by weight：The sulphur of sucrose eight
10 parts of acid esters sodium, 5 parts of bisabolol, 20 parts of solvent, 1 part of solubilizer, 50 parts of deionized water, 10 parts of Chinese medical extract, in described
Medicament extract is made from the following raw materials in parts by weight：3 parts of the root of kudzu vine, 3 parts of the coptis, 3 parts of golden cypress, 4 parts of radix glycyrrhizae, 6 parts of indigo naturalis, honeysuckle
10 parts, 4 parts of myrrh, 4 parts of the root of Dahurain angelica, 5 parts of adenosma indianum, 1 part of Radix Angelicae Sinensis, 6 parts of talcum.
The solubilizer is ethoxylated dodecyl alcohol -9.
The solvent is pentanediol.
The preparation method of the composition of described preventing diaper dermatitis, comprises the following steps：
(1) Chinese medical extract is prepared：Chinese medicine material is weighed by the important number, is broken to 30 mesh, adds 5 times of weights of Chinese medicine
The water of amount ratio, boils 20min by intense fire, uses slow fire instead and decocts, and the dregs of a decoction is filtered off after infusion 30min, it is standby that decoction is cooled to room temperature；
(2) sucrose octasulfate sodium, bisabolol, solvent, solubilizer, deionized water are weighed by the important number, first
Deionized water is heated to 60 DEG C, then adds sucrose octasulfate sodium, bisabolol, solvent and solubilizer, stirring makes fully
After dissolving, traditional Chinese medicine liquid is added, stirs, is cooled to normal temperature,.
The composition of described preventing diaper dermatitis is preparing the application of paper diaper surface layer non-woven cloth.
The composition of the preventing diaper dermatitis is added in conventional fibre spinning oil.
The composition of the preventing diaper dermatitis is used for non-woven cloth final finishing, first uses the composition of the preventing diaper dermatitis
Deionized water is diluted to 2wt% concentration, and then non-woven cloth is carried out with the composition of the preventing diaper dermatitis after the dilution
Arrange.
Embodiment 2
In the embodiment of the present invention, a kind of composition of preventing diaper dermatitis, it is made from the following raw materials in parts by weight：The sulphur of sucrose eight
19 parts of acid esters sodium, 7.5 parts of bisabolol, 30 parts of solvent, 3 parts of solubilizer, 75 parts of deionized water, 15 parts of Chinese medical extract, it is described
Chinese medical extract is made from the following raw materials in parts by weight：6 parts of the root of kudzu vine, 6 parts of the coptis, 6 parts of golden cypress, 7 parts of radix glycyrrhizae, 8 parts of indigo naturalis, gold and silver
Spend 15 parts, 6 parts of myrrh, 7 parts of the root of Dahurain angelica, 7 parts of adenosma indianum, 3 parts of Radix Angelicae Sinensis, 8 parts of talcum.
The solubilizer is ethoxylated dodecyl alcohol -9.
The solvent is pentanediol.
The preparation method of the composition of described preventing diaper dermatitis, comprises the following steps：
(1) Chinese medical extract is prepared：Chinese medicine material is weighed by the important number, is broken to 40 mesh, adds 7.5 times of Chinese medicine
The water of part by weight, boils 25min by intense fire, uses slow fire instead and decocts, and the dregs of a decoction are filtered off after infusion 30-40min, and decoction is cooled to room temperature
It is standby；
(2) sucrose octasulfate sodium, bisabolol, solvent, solubilizer, deionized water are weighed by the important number, first
Deionized water is heated to 70 DEG C, then adds sucrose octasulfate sodium, bisabolol, solvent and solubilizer, stirring makes fully
After dissolving, traditional Chinese medicine liquid is added, stirs, is cooled to normal temperature,.
The composition of described preventing diaper dermatitis is preparing the application of paper diaper surface layer non-woven cloth.
The composition of the preventing diaper dermatitis is added in conventional fibre spinning oil.
The composition of the preventing diaper dermatitis is used for non-woven cloth final finishing, first uses the composition of the preventing diaper dermatitis
Deionized water is diluted to 2wt% concentration, and then non-woven cloth is carried out with the composition of the preventing diaper dermatitis after the dilution
Arrange.
Embodiment 3
In the embodiment of the present invention, a kind of composition of preventing diaper dermatitis, it is made from the following raw materials in parts by weight：The sulphur of sucrose eight
28 parts of acid esters sodium, 10 parts of bisabolol, 40 parts of solvent, 5 parts of solubilizer, 100 parts of deionized water, 20 parts of Chinese medical extract, it is described
Chinese medical extract is made from the following raw materials in parts by weight：9 parts of the root of kudzu vine, 9 parts of the coptis, 9 parts of golden cypress, 10 parts of radix glycyrrhizae, 10 parts of indigo naturalis, gold
20 parts of honeysuckle flower, 8 parts of myrrh, 10 parts of the root of Dahurain angelica, 9 parts of adenosma indianum, 5 parts of Radix Angelicae Sinensis, 10 parts of talcum.
The solubilizer is ethoxylated dodecyl alcohol -9.
The solvent is pentanediol.
The preparation method of the composition of described preventing diaper dermatitis, comprises the following steps：
(1) Chinese medical extract is prepared：Chinese medicine material is weighed by the important number, is broken to 50 mesh, adds Chinese medicine 5-10
The water of times part by weight, boils 30min by intense fire, uses slow fire instead and decoct, the dregs of a decoction are filtered off after infusion 40min, decoction is cooled to room temperature
It is standby；
(2) sucrose octasulfate sodium, bisabolol, solvent, solubilizer, deionized water are weighed by the important number, first
Deionized water is heated to 80 DEG C, then adds sucrose octasulfate sodium, bisabolol, solvent and solubilizer, stirring makes fully
After dissolving, traditional Chinese medicine liquid is added, stirs, is cooled to normal temperature,.
The composition of described preventing diaper dermatitis is preparing the application of paper diaper surface layer non-woven cloth.
The composition of the preventing diaper dermatitis is added in conventional fibre spinning oil.
The composition of the preventing diaper dermatitis is used for non-woven cloth final finishing, first uses the composition of the preventing diaper dermatitis
Deionized water is diluted to 2wt% concentration, and then non-woven cloth is carried out with the composition of the preventing diaper dermatitis after the dilution
Arrange.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires rather than described above limits, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity
Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
It is appreciated that other embodiment.
Claims (9)
1. a kind of composition of preventing diaper dermatitis, it is characterised in that be made from the following raw materials in parts by weight：Sucrose octasulfate sodium
10-28 parts, bisabolol 5-10 parts, solvent 20-40 parts, solubilizer 1-5 parts, deionized water 50-100 parts, Chinese medical extract 10-
20 parts, the Chinese medical extract is made from the following raw materials in parts by weight：Root of kudzu vine 3-9 parts, coptis 3-9 parts, golden cypress 3-9 parts, radix glycyrrhizae
4-10 parts, indigo naturalis 6-10 parts, honeysuckle 10-20 parts, myrrh 4-8 parts, root of Dahurain angelica 4-10 parts, adenosma indianum 5-9 parts, Radix Angelicae Sinensis 1-5 parts, cunning
Stone 6-10 parts.
2. the composition of preventing diaper dermatitis according to claim 1, it is characterised in that by the raw material system of following parts by weight
Into：19 parts of sucrose octasulfate sodium, 7.5 parts of bisabolol, 30 parts of solvent, 3 parts of solubilizer, 75 parts of deionized water, traditional Chinese medicine extraction
15 parts of thing.
3. the composition of preventing diaper dermatitis according to claim 1 or 2, it is characterised in that the Chinese medical extract is under
The raw material of row parts by weight is made：6 parts of the root of kudzu vine, 6 parts of the coptis, 6 parts of golden cypress, 7 parts of radix glycyrrhizae, 8 parts of indigo naturalis, 15 parts of honeysuckle, myrrh 6
Part, 7 parts of the root of Dahurain angelica, 7 parts of adenosma indianum, 3 parts of Radix Angelicae Sinensis, 8 parts of talcum.
4. the composition of preventing diaper dermatitis according to claim 1 or 2, it is characterised in that the solubilizer is laruyl alcohol
APEO -9.
5. the composition of preventing diaper dermatitis according to claim 1 or 2, it is characterised in that the solvent is pentanediol.
A kind of 6. preparation method of the composition of preventing diaper dermatitis as described in claim 1-5 is any, it is characterised in that including
Following steps：
(1) Chinese medical extract is prepared：Chinese medicine material is weighed by the important number, is broken to 30-50 mesh, adds 5-10 times of Chinese medicine
The water of part by weight, boils 20-30min by intense fire, uses slow fire instead and decocts, and the dregs of a decoction are filtered off after infusion 30-40min, and decoction is cooled to
Room temperature is standby；
(2) sucrose octasulfate sodium, bisabolol, solvent, solubilizer, deionized water are weighed by the important number,
Deionized water is first heated to 60-80 DEG C, sucrose octasulfate sodium, bisabolol, solvent and solubilizer is then added, stirs
Mix after making fully dissolving, add traditional Chinese medicine liquid, stir, be cooled to normal temperature,.
7. the composition of preventing diaper dermatitis as claimed in claim 1 or 2 is preparing the application of paper diaper surface layer non-woven cloth.
8. application according to claim 7, it is characterised in that the composition of the preventing diaper dermatitis adds to conventional fibre spinning
In silk oiling agent.
9. application according to claim 7, it is characterised in that after the composition of the preventing diaper dermatitis is used for non-woven cloth
Arrange, the composition of the preventing diaper dermatitis is first diluted to 2wt% concentration with deionized water, then with after the dilution
The composition of preventing diaper dermatitis arranges to non-woven cloth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710973189.6A CN107693616A (en) | 2017-10-18 | 2017-10-18 | A kind of composition of preventing diaper dermatitis and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710973189.6A CN107693616A (en) | 2017-10-18 | 2017-10-18 | A kind of composition of preventing diaper dermatitis and its preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107693616A true CN107693616A (en) | 2018-02-16 |
Family
ID=61182735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710973189.6A Pending CN107693616A (en) | 2017-10-18 | 2017-10-18 | A kind of composition of preventing diaper dermatitis and its preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107693616A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112239953A (en) * | 2020-09-17 | 2021-01-19 | 江苏盛纳凯尔医用科技有限公司 | Non-woven fabric surface treatment finishing agent composition and preparation method and application thereof |
| CN114225092A (en) * | 2021-12-24 | 2022-03-25 | 浙江鹿达科技有限公司 | Skin moistening auxiliary agent prepared from non-woven fabric sanitary material |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2347571Y (en) * | 1998-03-04 | 1999-11-10 | 张为民 | Ecological health paper napkin trousers |
| CN102014979A (en) * | 2008-02-21 | 2011-04-13 | 赫克撒凯思公司 | Implantable medical device including a protection/retaining layer for an active ingredient or drug, in particular a water-soluble one |
| CN201996745U (en) * | 2010-12-11 | 2011-10-05 | 王丽娜 | Health care paper diaper |
| CN104474348A (en) * | 2014-12-15 | 2015-04-01 | 莫晓媚 | Traditional Chinese medicine for treating diaper rash and preparation method thereof |
-
2017
- 2017-10-18 CN CN201710973189.6A patent/CN107693616A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2347571Y (en) * | 1998-03-04 | 1999-11-10 | 张为民 | Ecological health paper napkin trousers |
| CN102014979A (en) * | 2008-02-21 | 2011-04-13 | 赫克撒凯思公司 | Implantable medical device including a protection/retaining layer for an active ingredient or drug, in particular a water-soluble one |
| CN201996745U (en) * | 2010-12-11 | 2011-10-05 | 王丽娜 | Health care paper diaper |
| CN104474348A (en) * | 2014-12-15 | 2015-04-01 | 莫晓媚 | Traditional Chinese medicine for treating diaper rash and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112239953A (en) * | 2020-09-17 | 2021-01-19 | 江苏盛纳凯尔医用科技有限公司 | Non-woven fabric surface treatment finishing agent composition and preparation method and application thereof |
| CN114225092A (en) * | 2021-12-24 | 2022-03-25 | 浙江鹿达科技有限公司 | Skin moistening auxiliary agent prepared from non-woven fabric sanitary material |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104740427B (en) | It is a kind of for the Chinese medicine composition of paper diaper and the preparation method of paper diaper | |
| CN101804166B (en) | Traditional Chinese medicine composition for treating dermatitis and eczema of infants | |
| CN103784659B (en) | A kind of Traditional Chinese medicine tincture preparation for the treatment of foot clavus | |
| CN102784337A (en) | Traditional Chinese medicine compound lotion for treating exudative infantile eczema and preparation method thereof | |
| CN107693616A (en) | A kind of composition of preventing diaper dermatitis and its preparation method and application | |
| CN102512620B (en) | External application traditional Chinese drug for treating psoriasis vulgaris | |
| CN104474391A (en) | Medicine for treating skin itch | |
| CN102861273B (en) | Preparation method of traditional Chinese medicine wet wipes for treating exudative children eczema | |
| CN106729100A (en) | With anti-inflammatory, the external application Chinese medicine health care preparation of beauty and preparation method thereof | |
| CN104547758A (en) | Medicine for treating qi-deficiency and blood-stasis type keloid and preparation method thereof | |
| CN106729117A (en) | It is a kind of to treat medicine of urinary tract infections and preparation method thereof | |
| CN111840497B (en) | Medicine for treating scars and preparation method thereof | |
| CN107789525A (en) | It is a kind of to treat the medicine of ulcer on the shank ulcer for many years not more and preparation method thereof | |
| CN107583016A (en) | A kind of cream for treating eczema and preparation method thereof | |
| CN106421087A (en) | Pharmaceutical preparation for treating acute eczema, and use of pharmaceutical preparation | |
| CN105194715A (en) | Non-woven fabric dressing for surgery and preparation method | |
| CN105250516A (en) | Combined preparation for oral administration and external use for treating haemorrhoids and preparation method of combined preparation | |
| CN104971203A (en) | Preparation for treating scabies and preparation method | |
| CN106620330B (en) | Chinese medicine hemostatic powder and preparation method thereof | |
| CN107198763A (en) | A kind of external application Chinese medicine for preventing and treating shank vein varicose and preparation method thereof | |
| CN105661054A (en) | Feed additive for sheep of 2-12 months old and preparation method of feed additive | |
| CN105362516A (en) | Tincture for treating plasmacellular mastitis and preparation method thereof | |
| CN104474268B (en) | A kind of external-applied ointment and preparation method for the treatment of diabetic ulcer | |
| CN104940710A (en) | Traditional Chinese medicine Kangning composition comprising soncretio silicea bambusae for treating epilepsy, and preparation method thereof | |
| CN104906416B (en) | A kind of Chinese medicine composition for treating type of hyperactivity of fire caused by deficiency of YIN purpura |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180216 |
|
| WD01 | Invention patent application deemed withdrawn after publication |