CN107669270A - A kind of magnetosonic Electrical imaging method and apparatus of electromagnetic focusing ultrasonic action - Google Patents
A kind of magnetosonic Electrical imaging method and apparatus of electromagnetic focusing ultrasonic action Download PDFInfo
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Abstract
A kind of magnetosonic Electrical imaging method and apparatus of electromagnetic focusing ultrasonic action, electromagnetic excitation source is applied on ultrasonic amplified medium by electrode emission pumping signal, produced on ultrasonic amplified medium and focus on ultrasound, ultrasonication is focused on to target imaging body, positive and negative charge separation is being produced in the presence of additional magnetostatic field in the target imaging body zone of action, internal field source is formed in target imaging body.After receiving electric signal by detection coil or detecting electrode, the electrical parameter image of target imaging body is rebuild using algorithm for reconstructing.In magnetosonic Electrical imaging device of the present invention, electromagnetic focusing ultrasonic action module connects coupling module by coupling liquid, coupling module is located in tank, coupling module is connected electromagnetic focusing ultrasonic action module and detection with synchronization module with rebuilding module respectively by detection coil or detecting electrode connecting detection with rebuilding module, control.
Description
Technical field
The present invention relates to a kind of magnetosonic Electrical imaging method and apparatus, more particularly to a kind of magnetosonic of electromagnetic focusing ultrasonic action
Electrical imaging method and apparatus.
Background technology
Using the electrical impedance imaging of tissue electrology characteristic, possess lossless and functional imaging technological merit, be after form, knot
The medical imaging procedure of new generation as after is formed, the early diagnosis for life science and disease has important valency
Value, a kind of brand-new diagnostic message can be provided for life science and clinic.On the one hand, when early lesion occurs for biological tissue
And not yet when producing change on morphosis, the space of all kinds of chemical substances electrically charged amount of institute and electric charge is divided in biological tissue
Cloth will change first, macroscopically show as the electrical characteristics (electrical impedance, electrical conductivity, dielectric constant) of diseased region biological tissue
Change, therefore by the lesion situation of the imaging can Non-Destructive Testing tissue to organizing electrical characteristics, so as to reach to disease
Become the purpose of tissue early diagnosis early treatment.The subcutaneous lymthoma of mouse that Nature reviews are delivered for 2008 is controlled
Treat in front and rear process detection it has also been found that structure does not change, but tumour cell quantity significantly reduces, and electrical property change is bright
It is aobvious, during further confirming tumor development, cell plasma concentration, electric charge distribution, water polarizability change and tissue
Electrical characteristics distribution is directly related.The expert Layton of american cancer research institute writes articles earlier than in December, 2006, it was confirmed that it is in breast
There is unique superiority, prophesy electrical impedance imaging will be with noninvasive, quick, high precision in the early diagnosis of gland cancer and prostate cancer
Rate, the advantage of low cost substitute biopsy, turn into the prefered method of clinical cancer diagnosis.On the other hand, electrical impedance imaging method can
Change during showing that each organ of human body completes physiological activity (such as breathing, heartbeat), not only can be to human body angiocarpy, food
The physiological activity such as road, stomach process carries out continuous dynamic monitoring, and can be found that the pathological change of some tissues of human body, such as
Canceration (Cherepenin 2001), encephaledema etc., therefore tool of the technology in terms of research human body physiological function and Deterioration mechanism
There is important value and be widely applied prospect.
Magnetosonic Electrical imaging method is 2008 to propose new method for conductivity imaging first, quick with imaging technique
Development, the imaging method are got growing concern for.On the Research foundation of methodology, main research at present concentrate on how
Meet in the low cost early diagnosis imaging system of clinical demand, to improve the resolution ratio and contrast of imaging, scholars are respectively
Studied from algorithm for reconstructing, ultrasonic action source, method for detecting weak signals etc., but at present imaging sensitivity and point
All have much room for improvement in terms of resolution.
The content of the invention
The purpose of the present invention is to overcome the shortcomings of existing magnetosonic Electrical imaging method in terms of resolution ratio and sensitivity, is proposed
A kind of magnetosonic Electrical imaging method and apparatus of electromagnetic focusing ultrasonic action.The present invention produces focusing by electromagnetic excitation mode and surpassed
Sound, focus on ultrasonication and produce electric signal in the presence of additional magnetostatic field to target imaging body, target imaging body.
The magnetosonic Electrical imaging method of electromagnetic focusing of the present invention ultrasonic action is：Electromagnetic excitation source is encouraged by electrode emission believes
Number it is applied on ultrasonic amplified medium, is produced on ultrasonic amplified medium and focus on ultrasound, focuses on ultrasonication to target imaging body.
Described focusing ultrasound is a kind of magnetic thermoacoustic signal, focuses on ultrasound in the presence of additional magnetostatic field in target imaging body active region
Positive and negative charge separation is produced in domain, internal field source is formed in target imaging body.Received by detection coil or detecting electrode
The electric signal of target imaging body, target imaging body electrical parameter image is rebuild using algorithm for reconstructing.
Include using the magnetosonic Electrical imaging device of electromagnetic focusing ultrasound excitation method of the present invention：Mould is motivated by ultrasound in electromagnetic focusing
Block, coupling module, detection are with rebuilding module and control and synchronization module.Electromagnetic focusing ultrasonic action module is connected by coupling liquid
Coupling module, coupling module are located in tank, and coupling module is by detection coil or detecting electrode connecting detection with rebuilding mould
Block, control are connected electromagnetic focusing ultrasonic action module and detection with synchronization module with rebuilding module respectively.Electromagnetic focusing ultrasound swashs
The controllable focusing ultrasound of flash, high-frequency, focal spot can be produced by encouraging module, and the caused ultrasound that focuses on is according to ultrasonic amplified medium
The difference of shape, including the ultrasonic and non axial focusing ultrasound of axial focusing；The function of coupling module is to realize to focus on ultrasound, target
The multiple physical field of imaging body and electromagnetic detection couples；Detection is to realize the detection of ultra-weak electronic signal with the major function for rebuilding module
With the reconstruction to target imaging body；The synchronous and control of whole device is realized in control with the function of synchronization module.
Described electromagnetic focusing ultrasonic action module is mainly by electromagnetic excitation source, ultrasonic amplified medium carrier, ultrasound enhancing
Dielectric coated and ultrasonic amplified medium injecting electrode composition.Electromagnetic excitation source is connected with ultrasonic amplified medium injecting electrode, ultrasound
Amplified medium injecting electrode is connected by conducting resinl with ultrasonic amplified medium coating, and ultrasonic amplified medium coating is fixed on ultrasound
On amplified medium carrier.
Electromagnetic excitation signal is launched in electromagnetic excitation source, and the signal of transmitting has pulse excitation signal, continuous wave frequency excitation letter
Number and specific modulated excitation signal.
Ultrasonic amplified medium coating is solid cladding or liquid coating, and ultrasonic amplified medium injecting electrode can be metal electricity
Pole or liquid electrode.When ultrasonic amplified medium coating is solid cladding, then ultrasonic amplified medium injecting electrode is gold
Belong to electrode, the material of electrode is silver electrode, copper electrode, gold-plated electrode or other metals.Ultrasonic amplified medium coating and ultrasound
Pass through conductive gemel connection between amplified medium injecting electrode.Described solid cladding is solidified metal film by CVD method
Formed on the inner surface of ultrasonic amplified medium carrier.The forming method of another solid cladding is by metallic film, including copper
Paper tinsel, tinfoil paper etc., directly it is affixed on the inner surface of ultrasonic amplified medium carrier.When ultrasonic amplified medium coating is liquid coating, surpass
Sound amplified medium injecting electrode is liquid electrode.Liquid electrode is located in flexible pipe, and the liquid in flexible pipe is as ultrasonic amplified medium
Injecting electrode is identical with ultrasonic amplified medium coating material.In flexible pipe insertion liquid coating.To prevent that liquid coating is excessive, profit
Liquid coating is sealed in the inner surface of ultrasonic amplified medium carrier with the dimethyl silicone polymer of solidification.Liquid coating is magnetic
Nanoparticles solution or carbon nano-particle solution.Solution of magnetic nanoparticles or carbon nano-particle solution are imported by flexible pipe.It is described
Flexible pipe be both used for loading liquid electrode, while exported again as liquid coating inlet port and liquid coating, with liquid coating phase
Connection.Liquid coating inlet port and liquid coating outlet are the replacings of liquid coating for convenience.Ultrasonic amplified medium coating is consolidated
It is scheduled on ultrasonic amplified medium carrier.
Described ultrasonic amplified medium carrier plays a part of solid shape and support to ultrasonic amplified medium coating.Ultrasound
Amplified medium inner surface of the carrier is spill, and ultrasonic amplified medium coating is convex, positioned at the interior table of ultrasonic amplified medium carrier
Face.The corresponding focal length for focusing on ultrasound of the radius of curvature on ultrasonic amplified medium coating convex surface, to obtain small focal spot, long-focus focuses on super
Sound.The ultrasonic preferred K9 glass of amplified medium carrier medium, it is also an option that ultraviolet vitreous silica, calcirm-fluoride, barium fluoride, fluorination
Magnesium, silicon, germanium, the dimethyl silicone polymer (PDMS) of plastics or shaping.It is ultrasonic to obtain axial focusing, in ultrasonic amplified medium
The preferred column concave shape in surface, corresponding ultrasonic amplified medium coating are then column convex.The shape of ultrasonic amplified medium carrier
Shape is sphere and cylinder.
Described coupling module includes tank, is placed in coupling liquid, magnet and position for transmitting ultrasonic signal in tank
In the removable support frame of tank inner support target imaging body.Target imaging body is placed on removable support frame.Coupling module is real
Now focus on the multiple physical field coupling of ultrasound, target imaging body and electromagnetic detection.Described magnetostatic field can be produced by permanent magnet,
It can be produced by electromagnet or superconducting magnet, magnet is located at outside tank, the direction of caused magnetostatic field and the direction for focusing on ultrasound
Vertically, magnetostatic field can regard a uniform magnetic field as in target imaging body.Gather as caused by being motivated by ultrasound module in electromagnetic focusing
Burnt ultrasound is applied to target imaging body by coupling liquid, and in the presence of magnetostatic field, target imaging body locally produces negative ions
Separation, therefore by detecting electrode, either detection coil can realize electric current or induction electric on the surface of target imaging body
The detection of gesture.
Described detection includes detecting electrode or detection coil, weak electromagnetic signal detection system and electricity ginseng with rebuilding module
Number rebuilds module, realizes the detection of ultra-weak electronic signal and the reconstruction to target imaging body.Electromagnetic excitation source and ultrasonic amplified medium
Injecting electrode connects, and pumping signal caused by electromagnetic excitation source is sent to ultrasonic amplified medium injecting electrode, ultrasonic amplified medium
Injecting electrode transmitting pumping signal is applied on ultrasonic amplified medium, and the ultrasound of focusing is produced on ultrasonic amplified medium, is focused on
Ultrasonication is to target imaging body, the generation positive and negative charge separation in the presence of additional magnetostatic field, and then in target imaging body
Form internal field source, the signal obtained by detecting electrode or detection coil enter the amplification of weak electromagnetic signal detection system and
After processing, module is rebuild into electrical parameter.Described Weak Signal Detection System is put including preamplifier, wave filter and two level
Big device three parts, the input connecting detection electrode or detection coil of preamplifier, the output end connection of preamplifier
The input of wave filter, the input of the output end connection two-stage amplifier of wave filter, the output end connection electricity of two-stage amplifier
The computer of Reconstruction module, the direct contact target imaging body of detecting electrode, detection coil and target imaging body are non-contact, lead to
The signal for crossing detecting electrode acquisition enters the amplification of weak electromagnetic signal detection system and handled, and mould is rebuild subsequently into electrical parameter
Block, electrical parameter rebuild module and realize that electrical parameter is rebuild.
Described control includes three dimensional scanning platform and signal generation apparatus with synchronization module, realizes the synchronization of whole device
And control.Signal generation apparatus send synchronizing signal be used to triggering the electromagnetic excitation source of electromagnetic focusing ultrasonic action module,
Three dimensional scanning platform, detection rebuild module and weak electromagnetic signal detection system with rebuilding the electrical parameter of module, realize whole dress
The work coordination put is consistent.Described three dimensional scanning platform includes three dimensional scanning platform controller, 3-D scanning support and stepping
Motor, three dimensional scanning platform controller connect stepper motor by serial ports, and stepper motor is installed on each of 3-D scanning support
Dimension, namely three dimensions, three stepper motors, three dimensional scanning platform controller control step under the control of signal generation apparatus
The movement of stepper motor, stepper motor often receive once command, then the mobile corresponding step-length in corresponding dimension, stops movement
The data of a position are then gathered afterwards, finally the data of collection are stored, the data after storage rebuild mould by electrical parameter
Block realizes the reconstruction of electrical parameter.
The frequency range of described electromagnetic excitation signal can be single pulse signal, also may be used in the range of 0.5MHz-5MHz
To be continuous wave frequency signal, specific modulation signal can also be.Such as 1MHz, continuous wave frequency signal can be
Frequency modulation is carried out in the range of 0.5MH to 1.5MHz to electromagnetic excitation signal, specific modulation signal includes triangular wave and sine wave
Coupling modulation.
Electromagnetic excitation source can be produced by signal waveform generator and power amplifier combination, be occurred first with signal
Device produces the signal waveforms such as required narrow pulse signal, linear FM signal, and caused signal is sent to and signal waveform
The power amplifier of generator connection, amplifies to signal, and the signal after amplification is sent to ultrasonic amplified medium injecting electrode, and then
Produce focus ultrasound signals.
It is as follows that electrical parameter rebuilds principle：
Target imaging body produces Lorentz force in the case where focusing on the collective effect of ultrasound and magnetostatic field：
F=qV × B0 (1)
Wherein, V is ionic agitation speed, B0For the magnetic induction intensity of magnetostatic field, F is Lorentz force, and q is electric charge；
In the presence of Lorentz force, local negative ions separation, produces electric current, local current densities in target imaging body
For：
Je=σ V × B0 (2)
Wherein JeFor current density, σ is the local conductivity of target imaging body；
Assuming that the direction of ultrasonic action is x directions, the direction of magnetostatic field is z directions, then the current density in y directions can be with
It is expressed as：
Iy(t)=WB0∫σ(x)v(x,t)dx (3)
Wherein Iy(t) it is the y directcd current densities that change with time t, W is the diameter of supersonic beam, and ∫ is integral sign, σ
(x) it is the electrical conductivity at x position, v (x, t) is the ionic agitation speed at t x position.
Utilize acoustic pressure equation：
Wherein, p (x, t) is acoustic pressure expression formula, and ρ (x) is density, then formula (3) is changed into：
According to formula (5), it is believed that in the density and electrical conductivity of focal spot target imaging body it is fixed, therefore can
To think that current density and local conductivity are proportional, directly can be changed by the electric signal received by amplitude anti-
Answer the change of electrical parameter.
Brief description of the drawings
The magnetosonic Electrical imaging apparatus structure schematic diagram of Fig. 1 electromagnetic focusing ultrasonic actions of the present invention；
Fig. 2 ultrasound amplified medium graphic layer structure schematic diagrames, wherein Fig. 2 a are liquid coating structural representation, and Fig. 2 b shaft types gather
Burnt ultrasonic amplified medium figure layer schematic diagram, Fig. 2 c are solid graphic layer structure schematic diagram；
In figure：A01 electromagnetic excitations source, A02 synchronizations and control module, A03 electrical parameters rebuild module, and A04 ultrasound enhancings are situated between
Matter carrier, A05 ultrasound amplified medium injecting electrodes, A06 weak electromagnetic signal detection systems, A07 three dimensional scanning platforms, A08 surpass
Sound amplified medium coating, the magnetostatic field devices of A09, A10 detecting electrodes, A11 target imaging bodies, A12 may move support frame, B01 liquid
Body coating, B02 liquid coating inlet ports, B03 shaft types focus on ultrasonic amplified medium B04 solid cladding B05 liquid coatings outlet.
Embodiment
The present invention is further illustrated below in conjunction with the drawings and specific embodiments.
The magnetosonic Electrical imaging method of electromagnetic focusing of the present invention ultrasonic action is：Electromagnetic excitation source is encouraged by electrode emission believes
Number it is applied on ultrasonic amplified medium, is produced on ultrasonic amplified medium and focus on ultrasound, focuses on ultrasonication to target imaging body,
Positive and negative charge separation is produced in the presence of additional magnetostatic field, internal field source is formed in target imaging body.Pass through detection line
After circle or detecting electrode receive the electric signal of target imaging body, target imaging body electrical parameter image is rebuild using algorithm for reconstructing.
As shown in figure 1, include using the magnetosonic Electrical imaging device of electromagnetic focusing ultrasound excitation method of the present invention：Electromagnetic focusing
Module, coupling module, detection is motivated by ultrasound with rebuilding module and control and synchronization module.Electromagnetic focusing ultrasonic action module passes through
Coupling liquid connects coupling module, and coupling module is located in tank, and coupling module passes through detection coil or detecting electrode connection inspection
Survey with rebuilding module, control is connected electromagnetic focusing ultrasonic action module and detection with synchronization module with rebuilding module respectively.Electromagnetism
The controllable focusing ultrasound of focusing ultrasonic action module generation flash, high-frequency, focal spot, caused focusing ultrasound can be axial direction
It can also be non-axial focusing ultrasound to focus on ultrasound；The function of coupling module is to realize to focus on ultrasound, target imaging body and electromagnetism
The multiple physical field coupling of detection；Detection is to realize the detection of ultra-weak electronic signal and to target imaging with the major function for rebuilding module
The reconstruction of body；Control is to realize the synchronous and control of whole device with the function of synchronization module.
Described coupling module include tank, be placed in tank be used for the coupling liquid for transmitting ultrasonic signal, magnetostatic field and
Positioned at tank inner support target imaging body A11 removable support frame A12.Target imaging body A11 is placed on removable support frame A12
On.Coupling module realizes the multiple physical field coupling for focusing on ultrasound, target imaging body and electromagnetic detection.Described magnetostatic field can be by
Permanent magnet is produced, and can also be produced by electromagnet and superconducting magnet, and the direction of caused magnetostatic field is hung down with focusing on the direction of ultrasound
Directly, caused magnetostatic field can regard a uniform magnetic field as in target imaging body, and the magnet for producing magnetostatic field is located at tank
Outside.Ultrasound is focused on as caused by being motivated by ultrasound module in electromagnetic focusing target imaging body is applied to by coupling liquid, in magnetostatic field
Under effect, target imaging body A11 locally produces the separation of negative ions, therefore passes through detection on target imaging body A11 surface
Either detection coil can realize the detection of electric current or induced electromotive force to electrode A 10.
Described electromagnetic focusing ultrasonic action module ultrasonic amplified medium carrier A04, surpasses mainly by electromagnetic excitation source A01
Sound amplified medium A08 and ultrasonic amplified medium injecting electrode A05 compositions.Electromagnetic excitation source A01 output ends output electromagnetic excitation letter
Number, electromagnetic excitation source A01 output end connects ultrasonic amplified medium injecting electrode A05 by wire.Ultrasonic amplified medium injection
Electrode A 05 is connected by conducting resinl with ultrasonic amplified medium coating, and ultrasonic amplified medium coating is fixed on ultrasonic amplified medium
On carrier A04.The signal of described electromagnetic excitation source transmitting has pulse excitation signal, continuous wave frequency pumping signal and specific
Modulated excitation signal.
Ultrasonic amplified medium injecting electrode A05 can be metal electrode or liquid electrode.When ultrasonic amplified medium
When A08 coatings are solid cladding, then ultrasonic amplified medium injecting electrode A05 is then metal electrode, and the material of its electrode is silver electricity
Pole, copper electrode, the electrode of gold-plated electrode or other metal materials, ultrasonic amplified medium injecting electrode A05 by conducting resinl with
Ultrasonic amplified medium A08 coatings are connected.When ultrasonic amplified medium coating A08 is liquid coating, liquid electrode is located at flexible pipe
It is interior, be filled with flexible pipe with ultrasonic amplified medium coating material identical liquid, this liquid is as ultrasonic amplified medium injecting electrode
A05, flexible pipe are inserted in liquid coating.To ensure that liquid coating is not excessive, liquid is applied using the dimethyl silicone polymer of solidification
Layer is sealed in the inner surface of ultrasonic amplified medium.Liquid coating is solution of magnetic nanoparticles or carbon nano-particle solution.Magnetic
Nanoparticles solution or carbon nano-particle solution are imported and exported by liquid coating inlet port and liquid coating outlet.Described is soft
Pipe had not only been used for loading liquid electrode simultaneously but also had been connected with liquid coating inlet port and liquid coating outlet, liquid coating inlet port
Positioned opposite with liquid coating outlet, angle between the two is 180 degree.Liquid coating inlet port and liquid coating outlet be for
Facilitate the replacing of liquid coating.Ultrasonic amplified medium coating is fixed on ultrasonic amplified medium carrier A04.
Described ultrasonic amplified medium carrier A04 plays a part of shape to ultrasonic amplified medium coating and fixes and support,
Ultrasonic amplified medium carrier A04 inner surfaces are spill.Ultrasonic amplified medium A08 coatings are convex, positioned at ultrasonic amplified medium
The inner surface of carrier.The corresponding focal length for focusing on ultrasound of the radius of curvature on ultrasonic amplified medium coating A08 convex surfaces, to obtain Xiao Jiao
Spot, long-focus focus on ultrasound.To obtain axial focusing ultrasound, ultrasonic amplified medium inner surface is column concave shape, ultrasound enhancing
Dielectric coated A08 is column convex, and ultrasonic amplified medium coating A08 is attached at ultrasonic amplified medium carrier A04 inner surface.
The ultrasonic amplified medium carrier A04 preferred K9 glass of material, it is also an option that ultraviolet vitreous silica, calcirm-fluoride, barium fluoride, fluorination
Magnesium, silicon, germanium, the dimethyl silicone polymer (PDMS) of plastics or shaping.
The output end in electromagnetic excitation source produces pumping signal, and its output end connects ultrasonic amplified medium by wire and injects electricity
Pole A05.Ultrasonic amplified medium coating A08 has two kinds of structures of solid cladding B04 and liquid coating B01.As shown in Figure 2 a, liquid applies
Layer B01 material is solution of magnetic nanoparticles or carbon nano-particle solution.Liquid coating B01 is by liquid coating inlet port B02
Imported with liquid coating outlet B05, flexible pipe exports B05 as liquid coating inlet port B02 and liquid coating, the liquid in flexible pipe
As ultrasonic amplified medium injecting electrode A05.
Liquid coating inlet port B02 and coating outlet B05 be connected with liquid coating B01, liquid coating inlet port B02 with
Liquid coating outlet B05 is positioned opposite.Ultrasonic amplified medium carrier A04 material can be glass, plastics or a kind of shaping
Dimethyl silicone polymer (PDMS), ultrasonic amplified medium carrier A04's is shaped as sphere and cylinder；Such as Fig. 2 b and Fig. 2 c institutes
Show, ultrasonic amplified medium carrier A04 cylinder focuses on ultrasonic amplified medium B03 for shaft type, focuses on sonification medium and is applied using liquid
Metal film is mainly solidificated in ultrasound by layer B01 or solid cladding B05, described solid cladding B05 by CVD method
On the inner surface of amplified medium carrier, another solid cladding B05 is by metal film, including the metallic film such as copper foil, tinfoil paper, directly
Connect the inner surface for being affixed on ultrasonic amplified medium carrier A04.Electromagnetic excitation source A01 can be put by signal waveform generator and power
Big device combination produces, the signal waveform such as narrow pulse signal, linear FM signal required for being produced first with signal generator,
The input that caused signal connects power amplifier by wire is amplified to signal, and the signal after amplification passes through wire
Ultrasonic amplified medium injecting electrode A05 is connected to, and then produces focus ultrasound signals.
Electromagnetic excitation source of the present invention in ultrasound by electrode emission electromagnetic excitation signal function to ultrasonic amplified medium, increasing
Produced on strong medium and focus on ultrasound, focused on ultrasonication to target imaging body A11, produced in the presence of additional magnetostatic field positive and negative
Separation of charge, and then internal field source is formed in imaging body, after receiving electric signal by detection coil or detecting electrode, utilize
Electrical parameter rebuilds the electrical parameter image that modules A 03 rebuilds target imaging body A11.Described magnetostatic field can be produced by permanent magnet
It can be produced by electromagnet, direction and the focus ultrasound signals caused by electromagnetic focusing ultrasonic action module of caused electromagnetic field hang down
It is straight.
The frequency range of described electromagnetic excitation signal can be single pulse signal, also may be used in the range of 0.5MHz-5MHz
To be continuous wave frequency signal, can also be specific modulation signal.Such as 1MHz, continuous wave frequency signal can be
Frequency modulation is carried out in the range of 0.5MH to 1.5MHz to electromagnetic excitation signal, specific modulation signal includes triangular wave and sine wave
Coupling modulation.
Described coupling module includes tank, is placed in for the coupling liquid for transmitting ultrasonic signal in tank, and positioned at water
Groove inner support target imaging body A11 removable support frame A12.Coupling module, which is realized, focuses on ultrasound, target imaging body A11 and electricity
The multiple physical field coupling of Magnetic testi.Ultrasound is focused on as caused by being motivated by ultrasound module in electromagnetic focusing target is applied to by coupling liquid
Imaging body A11, in the presence of magnetostatic field, target imaging body A11 locally produces the separation of negative ions, in target imaging body
By detecting electrode A10, either detection coil can detect electric current or induced electromotive force on surface.
Described detection includes detecting electrode A10 or detection coil, weak electromagnetic signal detection system A06 with rebuilding module
Modules A 03 is rebuild with electrical parameter, realizes the detection of ultra-weak electronic signal and the reconstruction to target imaging body A11.Described faint letter
Number detecting system A06 includes preamplifier, wave filter and two-stage amplifier three parts, the input connection inspection of preamplifier
Survey electrode or detection coil, the input of the output end connection wave filter of preamplifier, the output end connection two of wave filter
The input of level amplifier, the output end connection electrical parameter of two-stage amplifier rebuild the computer of module, and detecting electrode directly connects
Striking mark imaging body, detection coil and target imaging body are non-contact, and the signal obtained by detecting electrode A10 enters weak electromagnetic
After signal detection system A06 amplifies and handled, modules A 03 is rebuild into electrical parameter.
Described control includes three dimensional scanning platform A07 and signal generation apparatus with synchronization module, realizes whole device
Synchronous and control.Signal generation apparatus sends the electromagnetic excitation that a synchronizing signal is used to trigger electromagnetic focusing ultrasonic action module
Source A01, three dimensional scanning platform A07, detection rebuild modules A 03 and weak electromagnetic signal detection system with rebuilding the electrical parameter of module
A06, realize that the work coordination of whole device is consistent.Described three dimensional scanning platform includes three dimensional scanning platform controller, three-dimensional
Scanning bracket and stepper motor, three dimensional scanning platform controller connect stepper motor by serial ports, and stepper motor is installed on three-dimensional
Each dimension of scanning bracket, namely three dimensions, three stepper motors, three dimensional scanning platform controller fill in signal
The movement of control stepper motor under the control put, stepper motor often receive once command, then the mobile phase in corresponding dimension
The step-length answered, the data of a position are then gathered after stopping is mobile, finally the data of collection are stored, the data after storage
The reconstruction of electrical parameter is realized by electrical parameter reconstruction modules A 03.
The principle that electrical parameter is rebuild is as follows：
Target imaging body A11 produces Lorentz force in the case where focusing on the collective effect of ultrasound and magnetostatic field：
F=qV × B0 (1)
Wherein, V is ionic agitation speed, B0The magnetic induction intensity of magnetostatic field, F are Lorentz force, and q is electric charge；
In the presence of Lorentz force, negative ions separation, caused local current are locally produced in target imaging body A11
Density is：
Je=σ V × B0 (2)
Wherein, JeFor current density, σ is target imaging body A11 local conductivity；
Only consider a direction, it is assumed that the direction of ultrasonic action is x directions, and the direction of magnetostatic field is z directions, then in y side
To current density can be expressed as：
Iy(t)=WB0∫σ(x)v(x,t)dx (3)
Wherein Iy(t) it is the y directcd current densities that change with time t, W is the diameter of supersonic beam, and ∫ is integral sign, σ
(x) it is the electrical conductivity at x position, v (x, t) is the ionic agitation speed at t x position.
In view of acoustic pressure equation：
P (x, t) is acoustic pressure expression formula, and ρ (x) is density, then formula (3) is changed into：
According to formula (5), it is believed that in the density and electrical conductivity of focal spot target imaging body it is fixed, therefore can
To think that current density and local conductivity are proportional, can be changed by the electric signal received by amplitude directly anti-
Answer the change of electrical parameter.
Claims (10)
- A kind of 1. magnetosonic Electrical imaging method of electromagnetic focusing ultrasonic action, it is characterised in that：Described electromagnetic focusing ultrasonic action Magnetosonic Electrical imaging method be：Electromagnetic excitation source is applied on ultrasonic amplified medium by electrode emission pumping signal, in ultrasound Produced on amplified medium and focus on ultrasound, focus on ultrasonication to target imaging body；Ultrasound is focused in the presence of additional magnetostatic field Positive and negative charge separation is produced in the target imaging body zone of action, internal field source is formed in target imaging body, passes through detection Coil or detecting electrode receive the electric signal of target imaging body, and target imaging body electrical parameter image is rebuild using algorithm for reconstructing.
- 2. the magnetosonic Electrical imaging device of the electromagnetic focusing ultrasound excitation method described in application claim 1, it is characterised in that：It is described Device include：Electromagnetic focusing ultrasonic action module, coupling module, detection are with rebuilding module and control and synchronization module；Electromagnetism Focus on ultrasonic action module and coupling module is connected by coupling liquid, coupling module is located in tank, and coupling module passes through detection line Circle or detecting electrode connecting detection with rebuild module, control be connected respectively with synchronization module electromagnetic focusing be motivated by ultrasound module and Detection is with rebuilding module.
- 3. magnetosonic Electrical imaging device as claimed in claim 2, it is characterised in that：Described electromagnetic focusing ultrasonic action module by Electromagnetic excitation source, ultrasonic amplified medium carrier, ultrasonic amplified medium coating and ultrasonic amplified medium injecting electrode composition；Electromagnetism swashs Encourage source to be connected with ultrasonic amplified medium injecting electrode, ultrasonic amplified medium injecting electrode is applied by conducting resinl and ultrasonic amplified medium Layer is connected, and ultrasonic amplified medium coating is fixed on ultrasonic amplified medium carrier.
- 4. magnetosonic Electrical imaging device as claimed in claim 3, it is characterised in that：Described ultrasonic amplified medium inner surface of the carrier For spill；Ultrasonic amplified medium coating is convex, positioned at the inner surface of ultrasonic amplified medium carrier；Ultrasonic amplified medium coating The corresponding focal length for focusing on ultrasound of the radius of curvature on convex surface.
- 5. magnetosonic Electrical imaging device as claimed in claim 3, it is characterised in that：The shape of described ultrasonic amplified medium inner surface The preferred column concave shape of shape, corresponding ultrasonic amplified medium coating are then column convex.
- 6. magnetosonic Electrical imaging device as claimed in claim 3, it is characterised in that：The material of described ultrasonic amplified medium carrier It is preferred that K9 glass, it is also an option that ultraviolet vitreous silica, calcirm-fluoride, barium fluoride, magnesium fluoride, silicon, germanium, plastics or poly dimethyl silicon Oxygen alkane (PDMS).
- 7. magnetosonic Electrical imaging device as claimed in claim 3, it is characterised in that：When described ultrasonic amplified medium coating is solid During body coating, ultrasonic amplified medium injecting electrode is metal electrode；Ultrasonic amplified medium coating and ultrasonic amplified medium injection electricity Pass through conductive gemel connection between pole；Metal film is solidificated in ultrasonic amplified medium by described solid cladding by CVD method Formed on the inner surface of carrier, or metallic film is affixed on to the inner surface of ultrasonic amplified medium carrier and formed；When described ultrasonic amplified medium coating is liquid coating；Liquid electrode is filled with flexible pipe, is to be applied with ultrasonic amplified medium Layer material identical liquid, flexible pipe are inserted in liquid coating；Liquid coating is sealed in using the dimethyl silicone polymer of solidification The inner surface of ultrasonic amplified medium；Liquid coating is solution of magnetic nanoparticles or carbon nano-particle solution；Magnetic nanoparticle Solution or carbon nano-particle solution are imported and exported by liquid coating inlet port and liquid coating outlet；Liquid coating inlet port and Liquid coating outlet is positioned opposite, and angle between the two is 180 degree.
- 8. magnetosonic Electrical imaging device as claimed in claim 2, it is characterised in that：Described coupling module includes tank, is placed in It is used for the coupling liquid for transmitting ultrasonic signal, and the removable support positioned at tank inner support target imaging body (A11) in tank Frame (A12)；Target imaging body is placed on removable support frame (A12)；Magnet is located at outside tank, the direction of caused magnetostatic field with The direction for focusing on ultrasound is vertical.
- 9. magnetosonic Electrical imaging device as claimed in claim 2, it is characterised in that：Described detection includes detection with rebuilding module Electrode (A10) or detection coil, weak electromagnetic signal detection system (A06) and electrical parameter rebuild module (A03)；Described is faint Signal detection system (A06) includes preamplifier, wave filter and two-stage amplifier；The input connecting detection of preamplifier Electrode or detection coil, the input of the output end connection wave filter of preamplifier, the output end connection two level of wave filter The input of amplifier, the output end connection electrical parameter of two-stage amplifier rebuild the computer of module, and detecting electrode directly contacts Target imaging body, detection coil and target imaging body are non-contact, and the signal obtained by detecting electrode (A10) enters weak electromagnetic After signal detection system (A06) amplifies and handled, module (A03) is rebuild into electrical parameter.
- 10. magnetosonic Electrical imaging device as claimed in claim 2, it is characterised in that：Described control includes three with synchronization module Tie up scanning platform (A07 and) signal generation apparatus；Signal generation apparatus sends a synchronizing signal and surpassed for triggering electromagnetic focusing The electromagnetic excitation source (A01) of acoustically-driven module, three dimensional scanning platform (A07), detection rebuild module with rebuilding the electrical parameter of module (A03) and weak electromagnetic signal detection system (A06), control the work coordination of whole device consistent；Described 3-D scanning is put down Platform includes three dimensional scanning platform controller, 3-D scanning support and stepper motor, and three dimensional scanning platform controller is connected by serial ports Stepper motor is connect, stepper motor is installed on each dimension of 3-D scanning support, and three dimensional scanning platform controller is sent out in signal The movement of control stepper motor under the control of generating apparatus, stepper motor often receive once command, then are moved up in corresponding dimension Corresponding step-length is moved, the data of a position are then gathered after stopping is mobile, finally the data of collection are stored, after storage Data realize the reconstruction of electrical parameter by electrical parameter reconstruction module (A03).
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