CN107648581A - 一种治疗肾虚型经行腹泻的中药及其制备方法 - Google Patents

一种治疗肾虚型经行腹泻的中药及其制备方法 Download PDF

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CN107648581A
CN107648581A CN201711151079.8A CN201711151079A CN107648581A CN 107648581 A CN107648581 A CN 107648581A CN 201711151079 A CN201711151079 A CN 201711151079A CN 107648581 A CN107648581 A CN 107648581A
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王艳
马庆芬
袁红英
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Abstract

本发明公开了一种治疗肾虚型经行腹泻的中药,由以下重量的原料药制成,柴胡15克、夜交藤20克;甘草10克;干姜9克;大枣15克;神曲6克;桔梗7克、丹参5克;地肤子25克;山萸肉10克;枇杷叶10克;炒鸡内金10克;鹿血18克和牛髓20克;黄酒500ml。

Description

一种治疗肾虚型经行腹泻的中药及其制备方法
技术领域
本发明涉及一种治疗妇科病的药物,具体涉及一种治疗脾虚型经行腹泻的中药及其制备方法。
背景技术
经行腹泻对于此病的发病原因,现代西方医学认为与女性月经期间体内激素比例失调有关。而中医则认为经行泄泻多与素体脾虚肾弱有关。脾气虚弱,脾的运化水湿功能失常,所以出现泄泻 ;肾虚,命门清冷,不能温煦脾阳,也将导致泄泻。
中医对此病辨证施治,疗效显著。根据症状,将其分为脾虚和肾虚两类
(1)脾虚型:表现为行经期或行经之前,大便稀薄,或面目及四肢浮肿,腹部胀满,舌质淡红,舌苔白腻,饮食不思,神疲肢乏,经行量多,经色淡浅,经质稀薄,脉象濡缓。
若两胁胀满,兼腹痛即泻的经行腹泻。
(2)肾虚型:表现为头昏耳鸣,肢冷畏寒,经行大便泄泻,或清晨起床泄泻不止,腰骶酸软,月经色淡,经质清稀,舌苔白润,脉象沉迟。
发明内容
本发明要解决的技术问题,是针对上述技术方案的不足,提供一种治疗肾虚型经行腹泻的中药及其制备方法;该中药及其制备方法可有效的治疗肾虚型经行腹泻;有效的减轻头昏耳鸣,肢冷畏寒,经行大便泄泻,腰骶酸软的症状。
为解决上述技术问题本发明的技术方案为:
一种治疗肾虚型经行腹泻的中药,由以下重量的原料药制成,柴胡15克、夜交藤20克;甘草10克;干姜9克;大枣15克;神曲6克;桔梗7克、丹参5克;地肤子25克;山萸肉10克;枇杷叶10克;炒鸡内金10克;鹿血18克和牛髓20克;黄酒500ml。
以下是对上述技术方案的进一步改进:
将鹿血18克和牛髓20克充分混合,得血髓混合物A。
将柴胡15克;夜交藤20克;甘草10克;干姜9克和大枣15克;加入1000ml重量的水进行煎煮;然后保持沸腾状态30分钟;滤出药液得药液B。
将神曲6克;桔梗7克、丹参5克和地肤子25克加入500ml黄酒进行煎煮;煎煮至沸腾;保持沸腾状态;直到煎煮到黄酒剩余原黄酒量的1/3时停止煎煮;滤出药液得药液C;所余物用纱布包覆得固体物D。
将山萸肉10克;枇杷叶10克;炒鸡内金10克磨碎成细粉;过50目筛得外用粉E。
将药液C、药液B和血髓混合物A混合得口服药。
服用时,饮用口服药一日三次,将固体物D加热到40-50度后粘取外用粉置于如关元穴和三阴交穴热敷;也可热敷小腹处;一日三次。
本发明药物对肾虚型经行腹泻有很好的疗效,用药1经期,头昏耳鸣,81%的患者症状消失,92%的患者症状大为改善,其余无改变;2经期86%的患者症状消失,99%的患者症状大为改善,其余无改变;92%的患者症状消失,99%的患者症状大为改善,其余无改变。
肢冷畏寒症状一经期,76%的患者症状消失,89%的患者症状大为改善,其余无改变;二经期92%的患者症状消失,99%的患者症状大为改善,其余无改变;4经期99%的患者症状消失,其余无改变。
对治愈后的病例每间隔半年进行回访,3年内无复发,疗效稳定;本发明对脾虚型经行腹泻效果不佳;作用有限。
具体实施方式
实施例,一种治疗肾虚型经行腹泻的中药及其制备方法,由以下重量的原料药制成,柴胡15克、夜交藤20克;甘草10克;干姜9克;大枣15克;神曲6克;桔梗7克、丹参5克;地肤子25克;山萸肉10克;枇杷叶10克;炒鸡内金10克;鹿血18克和牛髓20克;黄酒500ml。
将鹿血18克和牛髓20克充分混合,得血髓混合物A。
将柴胡15克;夜交藤20克;甘草10克;干姜9克和大枣15克;加入1000ml重量的水进行煎煮;然后保持沸腾状态30分钟;滤出药液得药液B。
将神曲6克;桔梗7克、丹参5克和地肤子25克加入500ml黄酒进行煎煮;煎煮至沸腾;保持沸腾状态;直到煎煮到黄酒剩余原黄酒量的1/3时停止煎煮;滤出药液得药液C;所余物用纱布包覆得固体物D。
将山萸肉10克;枇杷叶10克;炒鸡内金10克磨碎成细粉;过50目筛得外用粉E。
将药液C、药液B和血髓混合物A混合得口服药。
服用时,饮用口服药一日三次,将固体物D加热到40-50度后粘取外用粉置于如关元穴和三阴交穴热敷;也可热敷小腹处;一日三次。
对近年来来我处就诊的肾虚型经行腹泻的患者进行治疗,统计结果如下。
本发明药物对肾虚型经行腹泻有很好的疗效,用药1经期,头昏耳鸣,81%的患者症状消失,92%的患者症状大为改善,其余无改变;2经期86%的患者症状消失,99%的患者症状大为改善,其余无改变;92%的患者症状消失,99%的患者症状大为改善,其余无改变。
肢冷畏寒症状一经期,76%的患者症状消失,89%的患者症状大为改善,其余无改变;二经期92%的患者症状消失,99%的患者症状大为改善,其余无改变;4经期99%的患者症状消失,其余无改变。
对治愈后的病例每间隔半年进行回访,3年内无复发,疗效稳定;本发明对脾虚型经行腹泻效果不佳;作用有限。

Claims (6)

1.一种治疗肾虚型经行腹泻的中药,其特征在于:由以下重量的原料药制成,柴胡15克、夜交藤20克;甘草10克;干姜9克;大枣15克;神曲6克;桔梗7克、丹参5克;地肤子25克;山萸肉10克;枇杷叶10克;炒鸡内金10克;鹿血18克和牛髓20克;黄酒500ml。
2.如权利要求1所述一种治疗肾虚型经行腹泻的中药的制备方法,其特征在于:将鹿血18克和牛髓20克充分混合,得血髓混合物A。
3.如权利要求1所述一种治疗肾虚型经行腹泻的中药的制备方法,其特征在于:将柴胡15克;夜交藤20克;甘草10克;干姜9克和大枣15克;加入1000ml重量的水进行煎煮;然后保持沸腾状态30分钟;滤出药液得药液B。
4.如权利要求1所述一种治疗肾虚型经行腹泻的中药的制备方法,其特征在于:将神曲6克;桔梗7克、丹参5克和地肤子25克加入500ml黄酒进行煎煮;煎煮至沸腾;保持沸腾状态;直到煎煮到黄酒剩余原黄酒量的1/3时停止煎煮;滤出药液得药液C;所余物用纱布包覆得固体物D。
5.如权利要求1所述一种治疗肾虚型经行腹泻的中药的制备方法,其特征在于:将山萸肉10克;枇杷叶10克;炒鸡内金10克磨碎成细粉;过50目筛得外用粉E。
6.如权利要求1所述一种治疗肾虚型经行腹泻的中药的制备方法,其特征在于:将药液C、药液B和血髓混合物A混合得口服药。
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101972432A (zh) * 2010-07-12 2011-02-16 泰一和浦(北京)中医药研究院有限公司 一种治疗经行泄泻的中药组合物及其制备方法
CN106039263A (zh) * 2016-07-13 2016-10-26 翁敏芬 一种治疗脾肾两虚证型经行泄泻病的中药
CN106075341A (zh) * 2016-07-13 2016-11-09 翁敏芬 一种治疗肾阳亏虚证型经行泄泻病的中药

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101972432A (zh) * 2010-07-12 2011-02-16 泰一和浦(北京)中医药研究院有限公司 一种治疗经行泄泻的中药组合物及其制备方法
CN106039263A (zh) * 2016-07-13 2016-10-26 翁敏芬 一种治疗脾肾两虚证型经行泄泻病的中药
CN106075341A (zh) * 2016-07-13 2016-11-09 翁敏芬 一种治疗肾阳亏虚证型经行泄泻病的中药

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