CN107643410A - The cleaning control method of sample analyser and sample analyser - Google Patents
The cleaning control method of sample analyser and sample analyser Download PDFInfo
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Abstract
The present invention relates to a kind of sample analyser, the sample analyser includes sample suction means, reaction tank, detector, cleaning fluid holding tank, liquid delivery device and cleaning controller, the sample suction means, which is drawn and transports sample to be tested to the reaction tank, measures reaction, the detector reacts measurement the detection that generated reactant carries out detection project, the cleaning fluid holding tank internal memory contains cleaning fluid, the cleaning controller is connected with sample suction means and detector to obtain detection parameters respectively, and judge whether remained reactant is exceeded according to detection parameters, when the reactant of residual is exceeded, the liquid delivery device is controlled to draw cleaning fluid out of cleaning fluid holding tank to perform cleaning operation.The invention further relates to a kind of cleaning control method of sample analyser.
Description
Technical field
A kind of cleaning control method the present invention relates to sample analyser and for cleaning the sample analyser.
Background technology
Existing sample analyser is usually required first when being measured using immune emulsion technique by sample to be tested and reaction
Reagent is reacted in reaction tank, and partial reaction thing can be remained in reaction tank after the completion of test.The residual reaction
Thing is accumulated to certain amount in reaction tank can then influence the degree of accuracy of subsequent measurement, so needing to enter the reactant of residual
Row cleaning.Common cleaning method cleans and at interval of periodic cleaning after a period of time after being included in detection every time.It is however, every
Cleaning is carried out after secondary detection and periodic cleaning reduces the effect cleaned on the used time while cleaning performance is ensured, it is difficult to meets mesh
The preceding requirement to test speed.
The content of the invention
In consideration of it, it is necessary to provide a kind of sample analyser of optimization and the cleaning control applied to the sample analyser
Method, the cleaning control method perform cleaning operation according to real-time measurement situation.
A kind of sample analyser, the sample analyser include sample suction means, reaction tank, detector, cleaning fluid and deposited
Storage tank, liquid delivery device and cleaning controller, the sample suction means are drawn and transport sample to be tested to the reaction tank
Reaction is measured, the detector reacts measurement the detection that generated reactant carries out detection project, the cleaning fluid
Holding tank internal memory contains cleaning fluid, and the cleaning controller is connected with sample suction means and detector to obtain detection respectively
Parameter, and judge whether remained reactant is exceeded, when the reactant of residual is exceeded, controls the liquid according to detection parameters
Body transmitting device draws cleaning fluid to perform cleaning operation out of cleaning fluid holding tank.
A kind of cleaning control method of sample analyser, the sample analyser are used for sample to be tested and reaction reagent institute
Caused reactant carries out the detection of detection project, and is set with least one threshold value related to reactant residual quantity, described
Cleaning control method comprises the following steps：
Obtain and store the detection parameters of detection project；
Compare acquired detection parameters and default threshold value；
Judge whether reactant residual quantity is exceeded according to comparative result；
Cleaning operation is carried out to sample analyser if reactant residual quantity is exceeded.
Relative to prior art, sample analyser provided by the present invention and applied to the cleaning on the sample analyser
Control method judges reactant residual quantity according to acquired detection parameters, and reasonably sets the cleaning of sample analyser accordingly
Opportunity so that reduced when the sample analyser is detected on the premise of ensureing that reactant residual quantity does not influence testing result
The number of cleaning, reduce testing cost while improve detection efficiency.
Brief description of the drawings
Fig. 1 is the structural representation for the sample analyser that first embodiment of the invention is provided.
Fig. 2 is the structural representation for the sample analyser that second embodiment of the invention is provided.
Fig. 3 is the step flow chart of cleaning control method provided by the invention.
Main element symbol description
| Sample analyser | 1 |
| Sample suction means | 10 |
| Reagent trough | 11 |
| Reaction tank | 12 |
| Detector | 13 |
| Cleaning fluid holding tank | 14 |
| Liquid delivery device | 15、25 |
| Human-computer interaction device | 16 |
| Memory | 17 |
| Processor | 18 |
| Bus | 100 |
| Cleaning controller | 19 |
| Liquid-transport pipe-line | 150 |
| Valve | 152 |
| Pump | 154 |
| Detection module | 190 |
| Setting module | 192 |
| Comparison module | 194 |
| Execution module | 196 |
| Driver | 250 |
| Liquid flowing tube | 252 |
Following embodiment will combine above-mentioned accompanying drawing and further illustrate the present invention.
Embodiment
First embodiment
As shown in figure 1, the sample analyser 1 that first embodiment of the invention is provided is used to carry out the sample to be tested gathered
Analysis.The analysis includes but is not limited to for Acute phase protein (C-reactive protein, CRP), leucocyte (White
Blood Cell, WBC), hemoglobin (Hemoglobin, HGB), red blood cell (Red Blood Cell, RBC), blood platelet
The detection of projects such as (Platelets, PLT).
The sample analyser 1 includes sample suction means 10, reagent trough 11, reaction tank 12, detector 13, cleaning fluid and deposited
Storage tank 14, liquid delivery device 15, human-computer interaction device 16, memory 17 and processor 18.The sample suction means 10, examination
Either directly or indirectly it is connected to carry out by liquid delivery device 15 between agent groove 11, reaction tank 12, cleaning fluid holding tank 14
The transmission of liquid.Between the sample suction means 10, detector 13, human-computer interaction device 16, memory 17 and processor 18
Either directly or indirectly it is electrically connected with by bus 100 to transmit and exchange data or signal.It is understood that the reagent
Groove 11, reaction tank 12, cleaning fluid holding tank 14 can also pass through bus 100 and above-mentioned sample suction means 10, detector 13, people
Machine interactive device 16, memory 17 and processor 18 are electrically connected with to transmit and exchange data or signal, realize Automated condtrol.
The sample suction means 10 is used to draw sample to be tested and import in reaction tank 12.The reagent trough 11 is used for
Reaction reagent required for storage analysis sample to be tested.It is understood that according to the sample to be tested to be analyzed, it is required
Reaction reagent can be one or more, and every kind of reaction reagent is individually deposited in a reagent trough 11.Therefore, the reagent trough
11 according to the sample to be tested to be analyzed can be one or more.
The reaction tank 12 is used to measure reaction, after sample to be tested is mixed with corresponding reaction reagent by predetermined ratio
Measure and react and reaction of formation thing in reaction tank 12.The detector 13 is used for the inspection that detection project is carried out to reactant
Survey, by measuring, the content of special component can draw the quantitative value that subject matter is tested in sample in reaction of formation thing.
The cleaning fluid holding tank 14 is used for store washing liquid.In the present embodiment, the cleaning fluid is hemolytic agent.Can
With understanding, if hemolytic agent is one of which reaction reagent, it is storable in reagent trough 11, cleaning fluid holding tank herein
14 can be substituted by one of reagent trough 11.
The human-computer interaction device 16 is used to realize the interactive operation between user and sample analyser 1, the interaction
Operation includes but is not limited to input instruction or data and output testing result.The human-computer interaction device 16 includes but is not limited to touch
Control display screen, keyboard, microphone.
The memory storage of memory 17 has the operating system for controlling sample analyser 1 to work.The operating system by
Processor 18 runs and interacted by human-computer interaction device 16 and user.The sample analyser 1 is in operating system
The every detection of lower execution is coordinated in control.
Cleaning controller 19 provided by the present invention is arranged in sample analyser 1, can be the son of the operating system
System, it can also be stored in independently of operating system in the memory 17 or to solidify in tough on the memory 17
Body (Firmware) by the operating system without directly being controlled.The cleaning controller 19 respectively with sample suction means 10 and
Detector 13 is connected, and judges reactant residual quantity to obtain the detection parameters of detection project, and according to the residual of reactant
Amount controls the liquid delivery device 15 to draw cleaning fluid out of cleaning fluid holding tank 14 to clean sample analyser 1.
In the present embodiment, the liquid delivery device 15 includes the defeated of connection cleaning fluid holding tank 14 and reaction tank 12
Liquid pipe road 150, valve 152 and pump 154.The cleaning controller 19 passes through the switch of control valve 152 and/or opening for pump 154
Close to determine that when draw cleaning fluid out of cleaning fluid holding tank 14 cleans to reaction tank 12.
The cleaning controller 19 includes detection module 190, setting module 192, comparison module 194 and execution module 196.
Above-mentioned module 190-196 can be the logical relation set being embedded on hardware or firmware, or be write with programming language
A series of programs being stored in memory 17 or other firmwares.Described program can be performed by least one processor 18 Lai
Realize specific function.
The detection module 190 is connected with the detector 13 and/or sample suction means 10 of sample analyser 1, is used for
Obtain the detection parameters of simultaneously detection project in storage reaction pond 12.Detection parameters acquired in the detection module 190 include inspection
The measured value and/or the sample size of sample to be tested corresponding with the measured value that survey project detects every time, acquired detection parameters
The designated area of the memory 17 is stored according to order.Here sample size can be the real sample body of sample to be tested
Product, such as the reference amount of 3ul, 5ul or sample to be tested, such as represent 1 sample size with 1.
The setting module 192 is connected with the human-computer interaction device 16, is set for the input operation according to user
The fixed threshold value related to reactant residual quantity.User can input threshold value by human-computer interaction device 16, and threshold value can protect in advance
Exist in memory 17 so that user calls.Set threshold value includes related to the detection project measured value in detection project
The first measurement threshold value or the related first sample amount threshold value or the second sample size of the second measurement threshold value, the sample size of sample to be tested
The threeth measurement threshold value related to the measured value cumulative total repeatedly measured in threshold value or detection project.It is understood that
For identical detection project, the second measurement threshold value can be that multiple different numerical value of threshold value are measured less than first, and every
One second measurement threshold value correspond to a first sample amount threshold value and judge the residual quantity of reactant to be collocated with each other.And for difference
Detection project, because the reactant that is generated is different, the first measurement threshold value, the second sample size threshold value, the 3rd measurement threshold value
Also the adjustment of adaptation can be made.
The comparison module 194 is connected with detection module 190 and setting module 192, for comparing by detection module 190
The detection parameters of acquisition and set corresponding threshold value, and judge whether reactant residual quantity is exceeded according to comparative result.
Specifically, the comparison module 194 is entered using detection parameters compared with least one set corresponding threshold value
The exceeded judgement of row residual quantity.Such as：Because being tested reaction of the subject matter content more at most generated in measurement reaction in sample
Thing is also more, so according to rational first measurement of tested subject matter content and the setting of the quantitative relation feature of institute's reaction of formation thing
Threshold value, when acquired measured value is more than or equal to the first set measurement threshold value, the comparison module 194 judges reaction
Thing residual quantity is exceeded, and when acquired measured value is less than the first set measurement threshold value, the comparison module 194 judges
Reactant residual quantity is not exceeded.
If the tested subject matter measured value detected every time is not less than the first measurement threshold value, even but relatively low measurement
Reactant caused by value also likely to be present exceeded risk after repeatedly adding up, so in another embodiment, detecting mould
Block 190 obtains the measured value of detection project and the sample size of sample to be tested corresponding with the measured value, as detection parameters.Setting
Module 192 sets the second measurement threshold value related to measured value, and the first sample amount threshold related to the sample size of sample to be tested
Value, the second measurement threshold value is less than the first measurement threshold value.When the measured value for the detection project that detection module 190 obtains is not above
First measurement threshold value, but more than second measurement threshold value when, detection module 190 can store the sample of sample to be tested corresponding to the measured value
This amount, can be by sample to be tested corresponding to the measured value when detection module 190 gets measured value again exceedes Second Threshold
Sample size and the sample size of last time add up, and obtain the first accumulative sample size, when the first accumulative sample size is more than or equal to the first sample
During this amount threshold value, the comparison module 194 judges that reactant residual quantity is exceeded, otherwise judges that reactant residual quantity is not exceeded.Example
Such as, the first measurement threshold value is 500, and the second measurement threshold value is 300, and first sample amount threshold value is 100ul, and detection module gets certain
The measured value of the detection project of individual sample to be tested is 400, and detection module 190 stores the sample of sample to be tested corresponding to the measured value
3ul is measured, when sample analyser continues to analyze sample to be tested, occurs more than 300 measured value again, detection module 190 can be deposited
The data of sample size corresponding to the measured value, such as 5ul are stored up, and is accumulated by the first accumulative sample size 8ul, is so repeated, such as
Fruit first adds up sample size more than 100ul, and comparison module 194 can be judged as that reactant residual quantity is exceeded.It is appreciated that here
Sample size or reference amount, because each sample size of sample analyser is probably fixed or difference is smaller, or it is right
The required precision of cleaning control is not high, can represent sample size once with 1, first sample amount threshold value could be arranged to 50.
If the measured value of the tested subject matter detected every time measures threshold value not less than first, but repeatedly remained after measurement
Reactant can be gradually accumulative and exceeded, so in a further embodiment, setting module 192 can also be set with having completed to detect
The second related sample size threshold value of the sample size of the sample to be tested of project, detection module 190 obtain and store each detection
The sample size of sample to be tested corresponding to purpose measured value, the aggregate-value of these sample sizes is counted, obtain the second accumulative sample size, when
When second accumulative sample size is more than or equal to the second sample size threshold value, the comparison module 194 judges that reactant residual quantity is exceeded,
And when the second accumulative sample size is less than the second set sample size threshold value, the comparison module 194 judges that reactant remains
Amount is not exceeded.Or in other examples, setting module 192 sets the threeth measurement threshold value related to measured value, detection
Module 190 obtains and stores the measured value of each detection project, counts the aggregate-value of these measured values, when aggregate-value is more than or waits
When the 3rd measurement threshold value, the comparison module 194 judges that reactant residual quantity is exceeded, and works as acquired measured value aggregate-value
During less than the 3rd set measurement threshold value, the comparison module 194 judges that reactant residual quantity is not exceeded.
It will be understood by those skilled in the art that the scheme that above-described embodiment is mentioned can be used alone, can also combine makes
For judging whether reactant residual is exceeded.
The execution module 196 is connected with comparison module 194 and detection module 190, for according to comparison module 194
Judged result control liquid delivery device 15 draws cleaning fluid to perform cleaning operation out of cleaning fluid holding tank 14.When comparing mould
The judged result of block 194 is to send execute instruction, the execution module 196 to execution module 196 when reactant residual quantity is exceeded
Liquid delivery device 15 is controlled to draw cleaning fluid out of cleaning fluid holding tank 14 to clean sample point after execute instruction is received
Analyzer 1.Sent when the judged result of comparison module 194 is not exceeded for reactant to the detection module 190 and continue detection and refer to
Order, so execution module 196 does not perform operation, and the detection module 190 continues to obtain detection parameters, the comparison module
194 pairs of detection parameters newly obtained continue to compare, persistently to be monitored to reactant residual quantity.And after often having performed once cleaning,
The execution module 196 is zeroed out to the detection parameters stored before detection module 190, to prevent false judgment reactant
Residual quantity and repeated washing.
It is understood that the cleaning to sample analyser 1 also includes in addition to being cleaned to the reaction tank 12
To the other parts of sample analyser 1, such as：Detector, Measurement channel and/or sampling channel etc. are cleaned.
Second embodiment
As shown in Fig. 2 the structure and first embodiment of the invention of the sample analyser 2 that second embodiment of the invention is provided
The structure of the sample analyser 1 provided is essentially identical, and its difference is：The liquid delivery device 25 includes driver 250
And liquid flowing tube 252.The driver 250 is connected with liquid flowing tube 252, for the liquid flowing tube 252 to be moved into predeterminated position.
The liquid flowing tube 252 is used to draw or discharge liquid.The execution module 196 of the cleaning controller 19 is connected with driver 250
Connect, for controlling driver 250 to drive liquid flowing tube 252 from cleaning fluid when comparison module 194 judges that reactant residual quantity is exceeded
Cleaning fluid is drawn in holding tank 14 to clean sample analyser 2.
The sample analyser 1 that embodiment of the present invention provides judges reactant residual quantity according to acquired detection parameters,
And the occasion of rinsing of sample analyser 1 is reasonably set accordingly so that ensureing to react when the sample analyser 1 is detected
Thing residual quantity does not influence to reduce the number of cleaning on the premise of testing result, reduces testing cost while improves detection effect
Rate.
A kind of cleaning control method of sample analyser is also disclosed in the application, and the sample analyser is used for sample to be tested
With reaction reagent caused by reactant carry out the detection of detection project, it is including sample suction means, reaction tank, detector, clear
Washing lotion holding tank, liquid delivery device.Cleaning control method is further illustrated with reference to above-mentioned sample analyser 1.
Comprise the following steps as shown in figure 3, Fig. 3 provides cleaning control method by embodiment of the present invention：
Step S101, obtain and store the detection parameters of detection project.The cleaning controller 19 is obtained by detection module 190
Take the detection parameters.Detection parameters acquired in the detection module 190 include the detection obtained by detector 13
The sample size that measured value that mesh detects every time and/or the sample to be tested obtained by sample suction means 10 are drawn.The inspection
The detection parameters acquired in module 190 are surveyed to be stored according to order in the designated area of the memory 17.People in the art
Member is it is appreciated that sample size can also obtain correlation values from the master control system of sample analyser.
Step S102, relatively acquired detection parameters and default threshold value.The sample analyser 1 passes through cleaning control
The setting module 192 of device 19 presets the threshold value related to reactant residual quantity.The threshold value can pass through man-machine friendship by user
Mutual equipment 16 inputs, and can also be pre-stored in memory 17 so that user calls.Set threshold value includes detection
Related to the detection project measured value the first measurement threshold value or the second measurement threshold value, the sample size of sample to be tested are related in mesh
Related to the measured value cumulative total repeatedly measured in first sample amount threshold value or the second sample size threshold value or detection project
Three measurement threshold values.It is understood that being directed to identical detection project, the second measurement threshold value can be less than the first measurement
Multiple different numerical value of threshold value, and every one second measurement threshold value correspond to a first sample amount threshold value and be judged instead with being collocated with each other
Answer the residual quantity of thing.And different detection projects is directed to, and because the reactant generated is different, the first measurement threshold value, second
Sample size threshold value, the 3rd measurement threshold value can also make the adjustment of adaptation.
By acquired detection parameters compared with least one default threshold value.
In one embodiment, can be using the measured value of the detection project of acquisition as detection parameters and the first measurement threshold value
Compare.
In another embodiment, the measured value of detection project and the sample of sample to be tested corresponding with the measured value are obtained
Amount, when measured value is more than the second measurement threshold value, the aggregate-value of the sample size of sample to be tested corresponding with the measured value is counted, is obtained
To the first accumulative sample size, compare the first accumulative sample size and first sample amount threshold value.Preferably, the second measurement threshold value is less than the
One measurement threshold value.
In yet another embodiment, the sample size for the sample to be tested for having completed detection project is obtained, statistics has been completed to detect
The aggregate-value of the sample size of the sample to be tested of project, the second accumulative sample size is obtained, compare the second accumulative sample size and the second sample
This amount threshold value.Preferably, the second sample size threshold value, which can be higher than, can also be less than first sample amount threshold value.
In the aggregate-value of the measured value for the detection project in one embodiment, counting acquisition, compare the aggregate-value and
Three measurement threshold values.
Step S103, judge whether reactant residual quantity is exceeded according to comparative result.The sample analyser 1 passes through cleaning
Whether the comparison module 194 of controller 19 judges reactant residual quantity according to above-mentioned result of the comparison according to default Rule of judgment
It is exceeded.The Rule of judgment includes but is not limited to：When acquired measured value is more than or equal to the first set measurement threshold value
When, the comparison module 194 judges that reactant residual quantity is exceeded, and when acquired measured value is less than the first set measurement
During threshold value, the comparison module 194 judges that reactant residual quantity is not exceeded；Add up when measuring more than the first of the second measurement threshold value
When sample size is more than or equal to first sample amount threshold value, the comparison module 194 judges that reactant residual quantity is exceeded, otherwise judges
Reactant residual quantity is not exceeded；When the completed detection project second accumulative sample size is more than or equal to the second set sample
During this amount threshold value, the comparison module 194 judges that reactant residual quantity is exceeded, otherwise judges that reactant residual quantity is not exceeded；When
When acquired measured value aggregate-value is more than or equal to the 3rd set measurement threshold value, the comparison module 194 judges reaction
Thing residual quantity is exceeded, and when acquired measured value aggregate-value is less than the 3rd set measurement threshold value, the comparison module
194 judge that reactant residual quantity is not exceeded.
User can select one of which Rule of judgment to judge the residual quantity of reactant.User can also
Judged simultaneously using multigroup Rule of judgment, formed immediately when wherein any one, the comparison module 194 can be to current anti-
The residual quantity situation of thing is answered to judge.
Step S104, the liquid delivery device 15 is controlled to be stored from cleaning fluid if judging that reactant residual quantity is exceeded
Cleaning fluid is drawn in groove 14 to clean sample analyser 1.When the judged result of comparison module 194 is exceeded for reactant residual quantity
Execute instruction is sent to execution module 196, the execution module 196 controls liquid delivery device 15 after execute instruction is received
Cleaning fluid is drawn out of cleaning fluid holding tank 14 to clean reaction tank 12.
Return to step S101 continues to obtain new detection parameters if judging that reactant residual quantity is not exceeded, repeat more than
Step S101- steps S104 is until detecting that reactant residual quantity is exceeded, so as to persistently be monitored to reactant residual quantity.
Step S105, after cleaning operation, the detection parameters of storage are zeroed out, i.e., after cleaning operation, statistics is each again
Aggregate-value, the repeated washing to prevent false judgment reactant residual quantity.
The sample analyser 1 and applied to the cleaning control method on the sample analyser 1 according to acquired inspection
Survey parameter and judge reactant residual quantity, and the occasion of rinsing of sample analyser 1 is reasonably set accordingly so that the sample analysis
The number of cleaning is reduced when instrument 1 is detected on the premise of ensureing that reactant residual quantity does not influence testing result, reduces inspection
Survey cost and improve detection efficiency simultaneously.
Although the present invention is disclosed above with embodiment, so it is not limited to the present invention, any art
Middle tool usually intellectual, it is without departing from the spirit and scope of the invention, therefore of the invention when a little change and retouching can be made
Protection domain when depending on after attached claim institute defender be defined.
Claims (15)
1. a kind of sample analyser, including sample suction means, reaction tank, detector, cleaning fluid holding tank, liquid delivery device
And cleaning controller, the sample suction means, which is drawn and transports sample to be tested to the reaction tank, measures reaction, described
Detector reacts measurement the detection that generated reactant carries out detection project, and the cleaning fluid holding tank internal memory contains cleaning
Liquid, the cleaning controller are connected to obtain detection parameters with sample suction means and detector, and joined according to detection respectively
Number judges whether remained reactant is exceeded, and the liquid delivery device is controlled when the reactant of residual is exceeded from cleaning fluid
Cleaning fluid is drawn in holding tank to perform cleaning operation.
2. sample analyser as claimed in claim 1, it is characterised in that：The cleaning controller includes detection module, setting
Module, comparison module and execution module, the detection module obtain and store the detection parameters, and the setting module is used to set
The fixed threshold value related to reactant residual quantity, the comparison module is connected with detection module and setting module, for comparing
The detection parameters of acquisition with set threshold value to judge whether reactant residual quantity exceeded, the execution module and comparison module
It is connected, for performing the cleaning operation according to the result of the comparison module.
3. sample analyser as claimed in claim 2, it is characterised in that：Also include human-computer interaction device, the man-machine interaction
Equipment is connected with the setting module, and the user is preset or adjusted described and reactant by the human-computer interaction device
The related threshold value of residual quantity.
4. sample analyser as claimed in claim 2, it is characterised in that：Acquired detection parameters are the detection project
Measured value, set threshold value includes the first related measurement threshold value of the detection project measured value, when the detection module obtains
Measured value be more than or equal to described first measurement threshold value when, the comparison module judges that reactant residual quantity is exceeded, described to hold
Row module control liquid delivery device draws cleaning fluid out of cleaning fluid holding tank and performs the cleaning operation.
5. sample analyser as claimed in claim 2, it is characterised in that：Acquired detection parameters include the survey of detection project
The sample size of value and sample to be tested corresponding with the measured value, set threshold value include detection project measured value correlation
Second measurement threshold value and the first sample amount threshold value related to the sample size of sample to be tested, when the measured value of the detection project surpasses
When crossing the second measurement threshold value, the detection module adds up the sample size of sample to be tested corresponding with the measured value, obtains first
Accumulative sample size, when the described first accumulative sample size is more than or equal to the first sample amount threshold value, the comparison module is sentenced
Disconnected reactant residual quantity is exceeded, and the execution module control liquid delivery device draws cleaning fluid execution out of cleaning fluid holding tank
The cleaning operation.
6. sample analyser as claimed in claim 2, it is characterised in that：Acquired detection parameters include having completed the inspection
The sample size of the sample to be tested of survey project, set threshold value include the sample size for having completed the sample to be tested of the detection project
The second related sample size threshold value, the sample of the accumulative sample to be tested for having completed the detection project of the detection module
Amount, the second accumulative sample size is obtained, when the described second accumulative sample size is more than or equal to the second sample size threshold value, the comparison
Module judges that reactant residual quantity is exceeded, and the execution module control liquid delivery device draws cleaning out of cleaning fluid holding tank
Liquid performs the cleaning operation.
7. sample analyser as claimed in claim 2, it is characterised in that：Acquired detection parameters include the survey of detection project
Value, set threshold value include the threeth measurement threshold value related to the detection project, and the detection module counts the detection
The aggregate-value of the measured value of project, when the aggregate-value is more than or equal to the described 3rd measurement threshold value, the comparison module is sentenced
Disconnected reactant residual quantity is exceeded, and the execution module control liquid delivery device draws cleaning fluid execution out of cleaning fluid holding tank
The cleaning operation.
8. sample analyser as claimed in claim 2, it is characterised in that：After cleaning operation is performed, the execution module pair
The detection parameters that detection module is stored before cleaning operation are zeroed out.
9. sample analyser as claimed in claim 1, it is characterised in that：The sample analyser includes the second reaction tank, institute
State sample to be tested and the second measurement reaction is carried out in second reaction tank with hemolytic agent, the second detector is reacted the second measurement
The second reactant for being generated carries out the detection of the second detection project, the hemolytic agent be stored in the cleaning fluid holding tank or
Second reaction tank described in person is the cleaning fluid holding tank.
10. a kind of cleaning control method of sample analyser, the sample analyser is used for sample to be tested and reaction reagent institute
Caused reactant carries out the detection of detection project, and is set with least one threshold value related to reactant residual quantity, described
Cleaning control method comprises the following steps：
Obtain and store the detection parameters of detection project；
Compare acquired detection parameters and default threshold value；
Judge whether reactant residual quantity is exceeded according to comparative result；
Cleaning operation is carried out to sample analyser if reactant residual quantity is exceeded.
11. cleaning control method as claimed in claim 10, it is characterised in that：Acquired detection parameters are detection project
Measured value, the threshold value include related to detection project measured value first and measure threshold value, be more than when acquired measured value or
Judge that reactant residual quantity is exceeded during equal to the first set measurement threshold value.
12. cleaning control method as claimed in claim 10, it is characterised in that：Acquired detection parameters include detection project
Measured value and sample to be tested corresponding with the measured value sample size, the threshold value includes measured the in detection project
Two measurement threshold values and the first sample amount threshold value related to the sample size of sample to be tested, when the measured value of the detection project exceedes
During the second measurement threshold value, the aggregate-value of the sample size of sample to be tested corresponding to the measured value is counted, obtains the first accumulative sample
Amount, when the described first accumulative sample size is more than or equal to the first sample amount threshold value, judge that reactant residual quantity is exceeded.
13. cleaning control method as claimed in claim 10, it is characterised in that：Acquired detection parameters include having completed institute
The sample size of the sample to be tested of detection project is stated, the threshold value includes the second sample size threshold value, the inspection has been completed described in statistics
The aggregate-value of the sample size of the sample to be tested of survey project, the second accumulative sample size is obtained, when the described second accumulative sample size is more than
Or judge that reactant residual quantity is exceeded during equal to the second sample size threshold value.
14. cleaning control method as claimed in claim 10, it is characterised in that：Acquired detection parameters include detection project
Measured value, the threshold value includes the related to the detection project the 3rd and measures threshold value, counts the measured value of the detection project
Accumulated value, when the aggregate-value be more than or equal to the described 3rd measurement threshold value when judge that reactant residual quantity is exceeded.
15. cleaning control method as claimed in claim 11, it is characterised in that：After also including cleaning operation, the inspection to storage
Parameter is surveyed to be zeroed out.
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020020169A1 (en) * | 2018-07-23 | 2020-01-30 | 深圳市帝迈生物技术有限公司 | Sample analyzing device and cleaning method thereof |
| CN110865018A (en) * | 2019-08-08 | 2020-03-06 | 上海交通大学医学院附属新华医院 | Sample post-processing system, device and method |
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| CN113811773A (en) * | 2019-05-13 | 2021-12-17 | 株式会社日立高新技术 | Automatic analyzer and cleaning method thereof |
| CN114618853A (en) * | 2022-05-11 | 2022-06-14 | 深圳市帝迈生物技术有限公司 | Cleaning method of sample analyzer and sample analyzer |
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| CN110865018A (en) * | 2019-08-08 | 2020-03-06 | 上海交通大学医学院附属新华医院 | Sample post-processing system, device and method |
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| CN112557447A (en) * | 2020-11-23 | 2021-03-26 | 深圳市科曼医疗设备有限公司 | Specific protein analysis method and control device based on blood cell analyzer |
| CN115524504A (en) * | 2021-06-25 | 2022-12-27 | 深圳市帝迈生物技术有限公司 | Sample analysis device, cleaning method thereof and computer-readable storage medium |
| CN114618853A (en) * | 2022-05-11 | 2022-06-14 | 深圳市帝迈生物技术有限公司 | Cleaning method of sample analyzer and sample analyzer |
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