CN107638452A - A kind of preparation method with the Chinese medicine composition for improving sleep effect - Google Patents

A kind of preparation method with the Chinese medicine composition for improving sleep effect Download PDF

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Publication number
CN107638452A
CN107638452A CN201710835907.3A CN201710835907A CN107638452A CN 107638452 A CN107638452 A CN 107638452A CN 201710835907 A CN201710835907 A CN 201710835907A CN 107638452 A CN107638452 A CN 107638452A
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China
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preparation
parts
chinese medicine
medicine composition
formula rate
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CN201710835907.3A
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Chinese (zh)
Inventor
李善姬
梁承武
张林豪
郑贤静
罗苗
刘廷廷
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Jilin Medical College
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Jilin Medical College
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Priority to CN201710835907.3A priority Critical patent/CN107638452A/en
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Abstract

The present invention relates to a kind of Chinese medicine composition that can improve sleep effect, said composition is by 50 150 parts of Wild jujube seeds extract;50 150 parts of Baical Skullcap root P.E;Capejasmine extract 50 150 forms, it is prepared according to a certain weight ratio, present invention also offers the preparation method of the Chinese medicine composition, composition is processed into the medicine or health food of the forms such as tablet, capsule, granule, powder, it is easy to use with various informative.Chinese medicine composition of the present invention is pure Chinese medicinal preparation, is had no toxic side effect, and can be effectively improved sleep, have a good application prospect.

Description

A kind of preparation method with the Chinese medicine composition for improving sleep effect
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of to improve Chinese medicine composition of sleep and preparation method thereof.
Background technology
Pressure with the work of present people, study, life constantly increases, and people's night sleep quality will decline, and go out The phenomenon now having a sleepless night, several aspects can be substantially shown as, the obstacle for the process of falling asleep is difficulty falling asleep, sleep quality declines Reduced with the length of one's sleep.
For cognition dysfunction in the daytime show as memory function decline, attention function decline, plan function reduction so as to Cause daytime sleepiness, ability to work declines, and easily occurs daytime sleepiness when being stopped, and body weight attenuating in a short time occurs, exempts from The problems such as attenuating of epidemic disease function and endocrine dysfunction.
The infringement brought to normal body of having a sleepless night is also embodied by the vegetative nerve function to cerebral limbic system and its surrounding Disorder, it is fixed that cardiovascular system shows as uncomfortable in chest, palpitaition, unstable blood pressure, and peripheral vessels shrinks extension obstacle;Digestive system manifestation is Constipation or diarrhoea, stomach are vexed swollen;Kinematic system shows as neck and shoulder part muscular tone, headache and pain in the back.Emotion control decreased capacity, It is easily offended or unhappy;Easily there is impotence in male, and the performances such as sexual function attenuating often occurs in women.
Nowadays insomnia problem is directed to, increasing people give with the symptom such as insomnia, dizziness, headache, forgetful, weak Patient brings the pain on huge body & mind.Western medicine insomnia effect is fast, but toxic side effect is big, is easily formed Rely on, and sleep quality can not be improved.But herbal treatment is used, there is no dependence to body, be preferred therapeutic modality, but That the course for the treatment of conditioning cycle is longer, but for long-term obstinate insomniac, using when treatment by Chinese herbs, it is necessary to spend more Time, easily worry, surface effect is not good situation, and abandons treating or using western medicine, so for losing Dormancy uses treatment by Chinese herbs good effect, takes stopgap measures and effects a permanent cure, but treatment cycle needs to be improved.
The content of the invention
Present invention aims to overcome that in place of the deficiencies in the prior art, shorten and grown with the cycle during treatment by Chinese herbs insomnia The problem of, realize that one kind has no toxic side effect Chinese medicine composition, there is provided Chinese medicine composition of positive effect and preparation method thereof.
In order to realize foregoing invention purpose, the invention provides a kind of Chinese medicine composition, the composition, including it is following heavy Measure the preparing raw material of part meter:Spina date seed 50-150 parts, radix scutellariae 50-150 parts, cape jasmine 50-150 parts, 5~15 parts of amber, pearl Female 5~15 parts, 1~5 part of borneol..
The property of medicine of Chinese medicine composition in the present invention is as follows:
Spina date seed:Nourishing the liver, calming heart, calm the nerves, arrest sweating.For treating restlessness of asrhenia type and insomnia, palpitation of palpitating with fear, polydipsia, abnormal sweating;Soothing the liver qi-regulating.
Radix scutellariae:There is heat-clearing and damp-drying drug, cool blood is antiabortive, detoxicating functions.Cure mainly warm heat disease cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery The diseases such as disease, hemoptysis, fetal irritability, hypertension.
Cape jasmine:Purging intense heat relieving restlessness, reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body, swelling and pain relieving.Cure mainly:Irascibility hot eyes, purging intense heat relieving restlessness, heat-clearing Diuresis, removing pattogenic heat from the blood and toxic material from the body.
Amber:Gas sweet taste, nontoxic, energy five viscera settling, analgesic are calmed the nerves.Treatment have no peace of mind, insomnia and dreamful sleep, palpitation with fear more help Benefit.
Mother-of-pearl:Soothing the liver, checking exuberance of yang, arresting convulsion, dizzy a, tinnitus is controlled, have a sleepless night, arresting convulsion of calming the nerves, clear liver and improve vision.
Borneol:Lead to all keys, dissipate stagnated fire, remove screen improving eyesight, swelling and pain relieving.Control apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm fan.
Preferably, Chinese medicine composition of the present invention can be made to various conventional agent together with pharmaceutically acceptable excipient Type, including tablet, pill or capsule, wherein by taking capsule as an example.
It is mixed present invention also offers a kind of Chinese medicine composition of the present invention with microcrystalline cellulose, starch and magnesium stearate Capsule.
Correspondingly, present invention also offers the preparation method of the Chinese medicine composition of above-mentioned improvement sleep, specifically include with Lower step:
(1) spina date seed, radix scutellariae, cape jasmine of formula rate, extracting in water, filtration are taken respectively;
(2) merging filtrate, it is concentrated into(60℃)Relative density is 1.20~1.25 medicinal extract;
(3) separately take the filtrate obtained by amber, mother-of-pearl and the step (2) of formula rate to dry jointly, and be broken into fine powder;
(4) it is another to take the borneol of formula rate to be mixed with the fine powder obtained by step (3), load capsule, be made.
The preferable spina date seed, radix scutellariae, cape jasmine for taking formula rate, the water of 8 ~ 10 times of amounts are added, extract 2 ~ 3 times, every time 1 ~ 5 Hour, filtration.
Preferable step (2) merging filtrate, using 50~70 DEG C, -0.06~-0.1Mpa's is concentrated under reduced pressure.
The preferable step (3) takes the filtrate obtained by amber, mother-of-pearl and the step (2) of formula rate jointly at 70 DEG C It is dried, and is broken into fine powder, crosses 100 female sieves.
The preferable step (4) takes the borneol of formula rate and the fine powder obtained by step (3) to mix, and loads capsule, often Grain 0.3g.
The Chinese medicine composition of the present invention is formulated according to theory of traditional Chinese medical science, and compatibility is reasonable, and each taste Chinese medicine is according to monarch Combination, fully takes into account the abundant extraction of various drug ingedients in composition, toxic side effect is small, and manufacturing cost is low.
The preparation of Chinese medicine composition of the present invention is used for the aspect for improving insomnia or health products, and process stabilizing can industrial metaplasia Production, is advantageous to popularization and application.
Embodiment
Presently preferred embodiments of the present invention is described in detail below, but the content is only the preferable implementation of the present invention Example, it is impossible to be considered as the practical range for limiting the present invention.All equivalent changes made according to the present patent application scope and improvement Deng, all should still belong to the present invention patent covering scope within.
Embodiment 1
The decocting that spina date seed 230g, radix scutellariae 200g, cape jasmine 200g are added to 8~10 times of amounts is boiled 3 times, every time 1.5 hours.Filtrate is closed And depressurize and use 50~70 DEG C, -0.06~-0.1Mpa concentrations are standby;Add amber 20g, mother-of-pearl 20g with it is above-mentioned Common 60-70 DEG C of medicinal extract dry, pulverize into fine powder(100 is female)Mixed again with borneol 4g, add auxiliary material, pelletized, dress capsule, every 0.3g。
Embodiment 2
The decocting that spina date seed 300g, radix scutellariae 280g, cape jasmine 280g are added to 8~10 times of amounts is boiled 3 times, every time 1.5 hours.Filtrate is closed And depressurize and use 50~70 DEG C, -0.06~-0.1Mpa concentrations are standby;Add amber 25g, mother-of-pearl 20g with it is above-mentioned Common 60~70 DEG C of medicinal extract dry, pulverize into fine powder(100 is female)Mixed again with borneol 5g, add auxiliary material, pelletized, dress capsule, every 0.3g。
Embodiment 3
The decocting that spina date seed 350g, radix scutellariae 300g, cape jasmine 310g are added to 8~10 times of amounts is boiled 3 times, every time 1.5 hours.Filtrate is closed And depressurize and use 50~70 DEG C, -0.06~-0.1Mpa concentrations are standby;Add amber 30g, mother-of-pearl 25g with it is above-mentioned Common 60~70 DEG C of medicinal extract dry, pulverize into fine powder(100 is female)Mixed again with borneol 6g, add auxiliary material, pelletized, dress capsule, every 0.3g。
Embodiment 4
The decocting that spina date seed 400g, radix scutellariae 400g, cape jasmine 400g are added to 8~10 times of amounts is boiled 3 times, every time 1.5 hours.Filtrate is closed And depressurize and use 50~70 DEG C, -0.06~-0.1Mpa concentrations are standby;Add amber 40g, mother-of-pearl 40g with it is above-mentioned Common 60~70 DEG C of medicinal extract dry, pulverize into fine powder(100 is female)Mixed again with borneol 8g, add auxiliary material, pelletized, dress capsule, every 0.3g。
Embodiment 5
The decocting that spina date seed 500g, radix scutellariae 450g, cape jasmine 430g are added to 8~10 times of amounts is boiled 3 times, every time 1.5 hours.Filtrate is closed And depressurize and use 50~70 DEG C, -0.06~-0.1Mpa concentrations are standby;Add amber 45g, mother-of-pearl 45g with it is above-mentioned Common 60~70 DEG C of medicinal extract dry, pulverize into fine powder(100 is female)Mixed again with borneol 9g, add auxiliary material, pelletized, dress capsule, every 0.3g。
Embodiment 6
The decocting that spina date seed 550g, radix scutellariae 500g, cape jasmine 450g are added to 8~10 times of amounts is boiled 3 times, every time 1.5 hours.Filtrate is closed And depressurize and use 50~70 DEG C, -0.06~-0.1Mpa concentrations are standby;Add amber 50g, mother-of-pearl 45g with it is above-mentioned Common 60-70 DEG C of medicinal extract dry, pulverize into fine powder(100 is female)Mixed again with borneol 10g, add auxiliary material, pelletized, dress capsule, every 0.3g。

Claims (7)

1. a kind of Chinese medicine composition for improving sleep effect, it is characterised in that include the preparing raw material of following parts by weight meter:Wild jujube Benevolence 50-150 parts, radix scutellariae 50-150 parts, cape jasmine 50-150 parts, 5~15 parts of amber, 5~15 parts of mother-of-pearl, 1~5 part of borneol.
A kind of 2. capsule, it is characterised in that:Including the composition described in claim 1, in addition to pharmaceutical adjunct is as diluted Agent, lubricant, there are lactose, microcrystalline cellulose, sucrose, starch, silica, talcum powder and magnesium stearate.
3. improving the preparation method of the Chinese medicine composition of sleep effect described in claim 1, comprise the steps of:
(1) spina date seed, radix scutellariae, cape jasmine of formula rate, extracting in water, filtration are taken respectively;
(2) merging filtrate, it is concentrated into(60℃)Relative density is 1.20~1.25 medicinal extract;
(3) separately the amber of formula rate, mother-of-pearl is taken to be dried jointly with the filtrate obtained by (2), and be broken into fine powder;
(4) it is another to take the borneol of formula rate to be mixed with the fine powder of (3), load capsule, be made.
4. the preparation method according to claim 3, it is characterised in that:The step (1) take formula rate spina date seed, Radix scutellariae, cape jasmine, the water of 8 ~ 10 times of amounts is added, extract 2 ~ 3 times, 1 ~ 5 hour every time, filter.
5. preparation method according to claim 3, it is characterised in that:Step (2) merging filtrate, using 50~70 DEG C, -0.06~-0.1Mpa's is concentrated under reduced pressure.
6. preparation method according to claim 3, it is characterised in that:The step (3) takes the amber of formula rate, pearl Mother is dried at 70 DEG C jointly with the filtrate obtained by step (2), and is broken into fine powder, crosses 100 female sieves.
7. preparation method according to claim 3, it is characterised in that:The step (4) takes the borneol and step of formula rate Suddenly the fine powder obtained by (3) mixes, and loads capsule, every 0.3g.
CN201710835907.3A 2017-09-16 2017-09-16 A kind of preparation method with the Chinese medicine composition for improving sleep effect Pending CN107638452A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1293966A (en) * 2000-09-11 2001-05-09 李恩复 Health-care product for improving sleep
CN103816498A (en) * 2014-03-26 2014-05-28 蚌埠火鹤制药有限公司 Traditional Chinese medicine mixture for treating sleep disorders
CN104940844A (en) * 2015-07-17 2015-09-30 青岛恒波仪器有限公司 Traditional Chinese medicine preparation for treating liver-fire flaming type palpitation and insomnia and preparation method thereof
CN105233089A (en) * 2015-11-20 2016-01-13 青岛金智高新技术有限公司 Traditional Chinese medicine preparation treating heart-kidney imbalance type insomnia

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1293966A (en) * 2000-09-11 2001-05-09 李恩复 Health-care product for improving sleep
CN103816498A (en) * 2014-03-26 2014-05-28 蚌埠火鹤制药有限公司 Traditional Chinese medicine mixture for treating sleep disorders
CN104940844A (en) * 2015-07-17 2015-09-30 青岛恒波仪器有限公司 Traditional Chinese medicine preparation for treating liver-fire flaming type palpitation and insomnia and preparation method thereof
CN105233089A (en) * 2015-11-20 2016-01-13 青岛金智高新技术有限公司 Traditional Chinese medicine preparation treating heart-kidney imbalance type insomnia

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
许军等: "疏风镇静养心安神治疗春季失眠36例", 《四川中医》 *
高翔龙: "自拟宁心安神汤治疗失眠85例", 《中国中医药现代远程教育》 *

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Application publication date: 20180130

RJ01 Rejection of invention patent application after publication