CN107629943A - A kind of freeze drying plant for carrying out bio-safety operation - Google Patents

A kind of freeze drying plant for carrying out bio-safety operation Download PDF

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Publication number
CN107629943A
CN107629943A CN201711100506.XA CN201711100506A CN107629943A CN 107629943 A CN107629943 A CN 107629943A CN 201711100506 A CN201711100506 A CN 201711100506A CN 107629943 A CN107629943 A CN 107629943A
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CN
China
Prior art keywords
freeze
area
operating space
carrying
drying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711100506.XA
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Chinese (zh)
Inventor
唐霜
邓菲
吴巧丽
张忠
唐小东
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Wuhan Institute of Virology of CAS
Original Assignee
Wuhan Institute of Virology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan Institute of Virology of CAS filed Critical Wuhan Institute of Virology of CAS
Priority to CN201711100506.XA priority Critical patent/CN107629943A/en
Publication of CN107629943A publication Critical patent/CN107629943A/en
Pending legal-status Critical Current

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Abstract

The present invention relates to a kind of freeze drying plant for carrying out bio-safety operation, including the battery limits below the filtering area and operating space above operating space, operating space, operating space is provided with table top, operation, which is divided into, is arranged side by side experimental implementation area and freeze-drying area, experimental implementation area is connected with freeze-drying area, the container equipped with sample is set to enter freeze-drying area from experimental implementation area, being provided with aperture at operating space front and back on table top makes operating space be connected with battery limits.By the air filter unit for setting experimental implementation area and correlation; make experimenter to have handled in the environment of bio-safety directly to transfer the sample into the area after sample treatment and be freeze-dried; whole process is all completed in the environment of bio-safety; avoid the mutual pollution problem between sample and environment; both the security of sample had been ensured, has also protected the health of experimenter and surrounding people.

Description

A kind of freeze drying plant for carrying out bio-safety operation
Technical field
The present invention relates to field of laboratory instrument equipment, more specifically it relates to a kind of freezing for carrying out bio-safety operation Drying device.
Background technology
Done for some laboratory samples especially thermal sensitivity sample in order to preserve or conveniently be quantified, it is necessary to carry out freezing for a long time Dry processing.
Some biological experiment operatings need gnotobasis, or the object of operation to be harmful to environment or operating personnel, Such experiment needs to carry out on Biohazard Safety Equipment or superclean bench.Biohazard Safety Equipment is pathogenic or non-available for carrying out The experimental works such as pathogenic organism sample treatment, cell and tissue culture, control of microorganisms, medicine preparation, to experimental implementation people Member, surrounding environment and/or sample play a protective role.Main application fields for example, cell/tissue culture, culture medium prepare, PCR, hematology, immunology and other non-harm, (non-) cause of disease sample operations etc..
In this case need to transfer on freeze drier after operating on Biohazard Safety Equipment.However, shifting Cheng Zhong, it is easy to by environmental pollution or pollution environment.Especially when sample has hyperinfection, it is more likely that jeopardize reality Test operating personnel or around other people health.
Therefore, it is necessary to a kind of freeze drying plant for carrying out bio-safety operation.
The content of the invention
To solve problem above, the invention provides a kind of freeze drying plant for carrying out bio-safety operation, including The battery limits below filtering area and the operating space above operating space, the operating space, the operating space are provided with table top, The operation, which is divided into, is arranged side by side experimental implementation area and freeze-drying area, the experimental implementation area and freeze-drying area's phase Connection, the container equipped with sample is set to enter the freeze-drying area from the experimental implementation area, on the table top described in Aperture is provided with operating space front and back makes the operating space be connected with the battery limits;
Position corresponding with the freeze-drying area is provided with freeze dryer in the battery limits, and the sample of the freeze dryer is done Dry room is through the table top in the freeze-drying area;
Powered air-purifying device and exhaust-air filter are provided with the filtering area.
By setting experimental implementation area and related air filter unit so that experimenter can be in the environment of bio-safety It is lower handled sample directly transfer the sample into freeze-drying area be freeze-dried, whole process is all in the environment of bio-safety Lower completion.Experimenter need not handle sample in Biohazard Safety Equipment, then sample is transferred into freezing from Biohazard Safety Equipment and done On dry machine, the mutual pollution problem between sample and environment is avoided, had both ensured the security of sample, also protect experiment people Member and the health of surrounding people.Outside air can be filtered into clean air by powered air-purifying device, and be sent into operating space;Air draft Filter can by freeze drying plant by the air filtration of sample pollution into clean air, be discharged in air, prevent around Environment is polluted by sample.In addition, the air come out from exhaust-air filter can also be disinfected first, then it is discharged into air.
In a preferred embodiment, be additionally provided with blower fan in the battery limits, the battery limits by pipeline with it is described Filter is connected.Blower fan work makes to produce negative pressure in operating space, and the air in operating space will not be excessive, so as to prevent testing people The air in member's suction experimental implementation area.The outside air that negative pressure causes to enter in operating space directly enters equipment by aperture Area, and filtering area is entered by blower fan and pipeline, then discharged from exhaust-air filter.
In one embodiment, the front in the experimental implementation area is provided with openable front window.Before experimenter is sitting in Experimental implementation is carried out before window.
In a preferred embodiment, the front window is opened by upper in-migration, is adjusted front window so as to easily in office Meaning position stops.
In one embodiment, the front in the freeze-drying area is provided with dismountable baffle plate, is set on the baffle plate The sterile gloves connecting hole of being and not being bacterium gloves connection, the sterile gloves is towards the freeze-drying area.Experimenter can lead to The sterile gloves is crossed to be operated in area is freeze-dried.
In a preferred embodiment, the table top at the aperture is provided with to lower recess.Experimenter is testing During, arm or hand, which rest on, will not block aperture on table top.
In a preferred embodiment, dividing plate is provided with by two between the freeze-drying area and the experimental implementation area Separate out, being provided with the dividing plate makes the freeze-drying area lead to what the experimental implementation area connected in the operating space Hole.Two are separated out with dividing plate the cross-infection that can be prevented between Liang Ge areas.The sample handled well can pass into freezing Dry section, the operation that then experimenter can be freeze-dried in freeze-drying area.
In a preferred embodiment, it is provided with closure gate on the through hole.Experimenter handles sample in experimental implementation area During product, closure gate closes through hole;After sample has been handled, closure gate is opened, the sample handled well is put into freeze-drying area, so The operation that experimenter can be freeze-dried in freeze-drying area afterwards.
In a preferred embodiment, it is additionally provided with transmission in the freeze drying plant for carrying out bio-safety operation Device connects the experimental implementation area and the freeze-drying area through the through hole.Experimenter can put the sample handled well On transmission device, and closure gate is opened, sample above is sent to freeze-drying area by transmission device, then shuts closure again Door.
Closure gate and transmission device can be set to link, and be controlled by switch.Sample is placed on transmission device by experimenter After upper, by lower switch, closure gate is opened, and sample is sent to freeze-drying area by transmission device.Then experimenter presses out again Close, closure gate is shut, transmission device stop motion.
Brief description of the drawings
Fig. 1 is the front view of one embodiment of the freeze drying plant for carrying out bio-safety operation of the present invention;
Fig. 2 is the operating space table top of one embodiment of the freeze drying plant for carrying out bio-safety operation of the present invention Schematic diagram;
Fig. 3 is the operating space signal of one embodiment of the freeze drying plant for carrying out bio-safety operation of the present invention Figure.
In accompanying drawing, the list of parts representated by each label is as follows:
1st, operating space, 2, filtering area, 3, battery limits, 4, freeze dryer, 5, blower fan, 6, sterile gloves hole connecting hole, 7, dividing plate, 8th, transmission device, 101, experimental implementation area, 102, freeze-drying area, 103, table top, 104, aperture, 201, powered air-purifying device, 202nd, exhaust-air filter, 401, sample drying room, 701, through hole, 702, closure gate.
Embodiment
The principle and feature of the present invention are described below in conjunction with example, the given examples are served only to explain the present invention, and It is non-to be used to limit the scope of the present invention.
As illustrated in fig. 1 and 2, the freeze drying plant for carrying out bio-safety operation of the invention, including operating space 1, institute The battery limits 3 below the filtering area 2 and the operating space of the top of operating space 1 are stated, the operating space is provided with table top 103, institute State operation and divide into and experimental implementation area 101 and freeze-drying area 102, the experimental implementation area 101 and the freezing is arranged side by side Dry section 102 is connected, and the container equipped with sample is entered the freeze-drying area 102, institute from the experimental implementation area 101 State and be provided with aperture 104 at the operating space front and back on table top 103 and make the operating space and the equipment Area 3 connects;
The freeze-drying 102 corresponding position of area is provided with freeze dryer 4 in the battery limits 3, the freeze dryer 4 Sample drying room 401 is through the table top 103 in the freeze-drying area 102;
Powered air-purifying device 201 and exhaust-air filter 202 are provided with the filtering area 2.
By setting experimental implementation area and related air filter unit so that experimenter can be in the ring of bio-safety Handled under border and freeze-drying area is directly transferred the sample into after sample be freeze-dried, whole process is all in bio-safety Completed under environment.Experimenter need not handle sample in Biohazard Safety Equipment, then sample is transferred to from Biohazard Safety Equipment cold On lyophilizer, the mutual pollution problem between sample and environment is avoided, the security of sample had both been ensured, and had also protected reality Test the health of personnel and surrounding people.Outside air can be filtered into clean air by powered air-purifying device, and be sent into operating space; Exhaust-air filter can by freeze drying plant by sample pollution air filtration into clean air, be discharged in air, prevent Surrounding environment is polluted by sample.In addition, the air come out from exhaust-air filter can also be disinfected first, then it is discharged into air In.
In a preferred embodiment, blower fan 5 is additionally provided with the battery limits 3, the battery limits 3 pass through pipeline and institute Filter 2 is stated to be connected.Blower fan work makes to produce negative pressure in operating space, and air of the operating space especially in experimental implementation area will not It is excessive, so as to prevent experimenter from sucking the air in experimental implementation area.The outside air that negative pressure causes to enter in operating space is straight Connect small holes 104 and enter battery limits, and filtering area is entered by blower fan and pipeline, then discharged from exhaust-air filter.
In one embodiment, the front in the experimental implementation area 101 is provided with openable front window.Experimenter is sitting in Experimental implementation is carried out before front window.
In a preferred embodiment, the front window is opened by upper in-migration, is adjusted front window so as to easily in office Meaning position stops.
In one embodiment, the front in the freeze-drying area 102 is provided with dismountable baffle plate, is set on the baffle plate The sterile gloves connecting hole 6 being connected with sterile gloves is equipped with, the sterile gloves is freeze-dried area 102 towards described.Test people Member can be operated by the sterile gloves in area is freeze-dried.
In a preferred embodiment, the table top 103 at the aperture 104 is provided with to lower recess.Experimenter In experimentation, arm or hand, which rest on, will not block aperture on table top.
In a preferred embodiment, as shown in figure 3, between the freeze-drying area 102 and the experimental implementation area 101 It is provided with dividing plate 7 to separate out two, being provided with the dividing plate makes the freeze-drying area 102 and the experimental implementation area 101 through holes 701 connected in the operating space 1.Two are separated out with dividing plate the cross-infection that can be prevented between Liang Ge areas. The sample handled well can pass into freeze-drying area, the behaviour that then experimenter can be freeze-dried in freeze-drying area Make.
In a preferred embodiment, it is provided with closure gate 702 on the through hole 701.Experimenter is in experimental implementation area When handling sample, closure gate closes through hole;After sample has been handled, closure gate is opened, it is dry that the sample handled well is put into freezing Dry area, the operation that then experimenter can be freeze-dried in freeze-drying area.
In a preferred embodiment, it is additionally provided with transmission in the freeze drying plant for carrying out bio-safety operation Device connects the experimental implementation area 101 and the freeze-drying area 102 through the through hole 701.Experimenter will can be handled Good sample is placed on transmission device, and opens closure gate, and sample above is sent to freeze-drying area by transmission device, then Closure gate is shut again.
Closure gate and transmission device can be set to link, and be controlled by switch.Sample is placed on transmission device by experimenter After upper, by lower switch, closure gate is opened, and sample is sent to freeze-drying area by transmission device.Then experimenter presses out again Close, closure gate is shut, transmission device stop motion.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and Within principle, any modification, equivalent substitution and improvements made etc., it should be included in the scope of the protection.

Claims (9)

1. above a kind of freeze drying plant for carrying out bio-safety operation, including operating space (1), the operating space (1) Battery limits (3) below filtering area (2) and the operating space, the operating space are provided with table top (103), it is characterised in that It is described operation divide into is arranged side by side experimental implementation area (101) and freeze-drying area (102), the experimental implementation area (101) and Freeze-drying area (102) is connected, and the container equipped with sample is entered the freezing from the experimental implementation area (101) Dry section (102), being provided with aperture (104) at the operating space front and back on the table top (103) makes the institute Operating space is stated to connect with the battery limits (3);
Position corresponding with freeze-drying area (102) is provided with freeze dryer (4), the freeze dryer in the battery limits (3) (4) sample drying room (401) is through the table top (103) in freeze-drying area (102);
Powered air-purifying device (201) and exhaust-air filter (202) are provided with the filtering area (2).
2. the freeze drying plant according to claim 1 for carrying out bio-safety operation, it is characterised in that the equipment Blower fan (5) is additionally provided with area (3), the battery limits (3) are connected by pipeline with the filter (2).
3. the freeze drying plant according to claim 1 for carrying out bio-safety operation, it is characterised in that the experiment The front of operating space (101) is provided with openable front window.
4. the freeze drying plant according to claim 3 for carrying out bio-safety operation, it is characterised in that the front window Opened by upper in-migration.
5. the freeze drying plant according to claim 1 for carrying out bio-safety operation, it is characterised in that the freezing The front of dry section (102) is provided with dismountable baffle plate, and the hole being connected with aseptic operation gloves is provided with the baffle plate (6), the sterile gloves is freeze-dried area (102) towards described.
6. the freeze drying plant according to claim 1 for carrying out bio-safety operation, it is characterised in that set The table top (103) at aperture (104) place is stated to lower recess.
7. according to the freeze drying plant for carrying out bio-safety operation described in claim 1-6, it is characterised in that described Dividing plate (7) is provided between freeze-drying area (102) and the experimental implementation area (101) to separate out two, on the dividing plate It is provided with the through hole for making freeze-drying area (102) be connected with the experimental implementation area (101) in the operating space (1) (701)。
8. the freeze drying plant according to claim 7 for carrying out bio-safety operation, it is characterised in that the through hole (701) closure gate (702) is provided with.
9. the freeze drying plant according to claim 7 for carrying out bio-safety operation, it is characterised in that be additionally provided with Transmission device connects the experimental implementation area (101) and freeze-drying area (102) through the through hole (701).
CN201711100506.XA 2017-11-09 2017-11-09 A kind of freeze drying plant for carrying out bio-safety operation Pending CN107629943A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711100506.XA CN107629943A (en) 2017-11-09 2017-11-09 A kind of freeze drying plant for carrying out bio-safety operation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711100506.XA CN107629943A (en) 2017-11-09 2017-11-09 A kind of freeze drying plant for carrying out bio-safety operation

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Publication Number Publication Date
CN107629943A true CN107629943A (en) 2018-01-26

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060254076A1 (en) * 2005-04-13 2006-11-16 Gea Lyophil Gmbh Method for the operation of freeze-drying equipment with a chamber and with loading and unloading devices, including equipment of this kind appropriately designed for such purpose
CN102032770A (en) * 2010-12-28 2011-04-27 上海东富龙科技股份有限公司 Aseptic isolator for fixed automatic feeding and discharging on vacuum freeze drier
CN201959803U (en) * 2010-12-28 2011-09-07 上海东富龙科技股份有限公司 Purifying and isolating device assorted with aseptic freeze-dried preparation production line
CN202915656U (en) * 2012-07-11 2013-05-01 游金铭 Dust-free and sterile freeze dryer
CN203581770U (en) * 2013-06-28 2014-05-07 山东新华医疗器械股份有限公司 Bulk drug charging and discharging dolly
CN205860664U (en) * 2016-07-06 2017-01-04 山东新华医疗器械股份有限公司 The aseptic freeze-dried separator system of use for laboratory medicine
CN207659421U (en) * 2017-11-09 2018-07-27 中国科学院武汉病毒研究所 A kind of freeze drying plant carrying out bio-safety operation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060254076A1 (en) * 2005-04-13 2006-11-16 Gea Lyophil Gmbh Method for the operation of freeze-drying equipment with a chamber and with loading and unloading devices, including equipment of this kind appropriately designed for such purpose
CN102032770A (en) * 2010-12-28 2011-04-27 上海东富龙科技股份有限公司 Aseptic isolator for fixed automatic feeding and discharging on vacuum freeze drier
CN201959803U (en) * 2010-12-28 2011-09-07 上海东富龙科技股份有限公司 Purifying and isolating device assorted with aseptic freeze-dried preparation production line
CN202915656U (en) * 2012-07-11 2013-05-01 游金铭 Dust-free and sterile freeze dryer
CN203581770U (en) * 2013-06-28 2014-05-07 山东新华医疗器械股份有限公司 Bulk drug charging and discharging dolly
CN205860664U (en) * 2016-07-06 2017-01-04 山东新华医疗器械股份有限公司 The aseptic freeze-dried separator system of use for laboratory medicine
CN207659421U (en) * 2017-11-09 2018-07-27 中国科学院武汉病毒研究所 A kind of freeze drying plant carrying out bio-safety operation

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