CN106393181A - Bio-security type glove box type isolator - Google Patents
Bio-security type glove box type isolator Download PDFInfo
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- CN106393181A CN106393181A CN201610819092.5A CN201610819092A CN106393181A CN 106393181 A CN106393181 A CN 106393181A CN 201610819092 A CN201610819092 A CN 201610819092A CN 106393181 A CN106393181 A CN 106393181A
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- exhaust
- air filter
- air
- isolator
- filter
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
- B25J21/00—Chambers provided with manipulation devices
- B25J21/02—Glove-boxes, i.e. chambers in which manipulations are performed by the human hands in gloves built into the chamber walls; Gloves therefor
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- Robotics (AREA)
- Mechanical Engineering (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Filtering Of Dispersed Particles In Gases (AREA)
Abstract
The invention discloses a bio-security type glove box type isolator. The bio-security type glove box type isolator comprises an operation box body, wherein an equipment layer is arranged on the upper side of the operation box body, and a bracket is arranged on the lower side of the operation box body; a first stage air exhaust filtering device and an air blowing filtering device are mounted at the bottom of the equipment layer; the operation box body communicates with the first stage air exhaust filtering device and the air blowing filtering device; a second stage air exhaust filtering device which communicates with the first stage air exhaust filtering device is mounted at the bottom of the bracket; the right end of the second stage air exhaust filtering device communicates with a gas disinfectant discharging opening and a fan; operating gloves are arranged on the front surface of the operation box body; an equipment door is mounted in the left side wall, and a first airtight door is mounted in the right side wall; and the first airtight door communicates with a transmission barrel in which the second airtight door is mounted. The bio-security type glove box type isolator disclosed by the invention has good structural rigidity and good visibility; home position leak detection and disinfection can be performed on a high-efficiency air blowing filter and a high-efficiency air exhaust filter; and articles can be transmitted in an air tightness manner, and the purpose that an experimenter can perform various experimental operations including performing inspection and analysis on strong pathogenic microbes can be met.
Description
Technical field
The present invention relates to the isolation of biological safety protection and equipment technology field, more particularly to biological safe type glove box type
Device.
Background technology
At present, in order to quickly and accurately be diagnosed it is often necessary to complete to the carrying out of pathogenic microorganism to infectious diseases
The inspection in face and analysis.In view of pathogenic microorganism is that have pathogenic microorganism to people and animals and plants, it easily causes infection
Even infectious disease, therefore carrying out to pathogenic microorganism detecting, tests etc. in operating process, easily forms harmful biogas molten
Glue, if harmful bioaerosol diffuses to experiment interior, it will greatly increase the disease infection risk of staff, sternly
Threaten the personal safety of staff again, or even serious pollution is caused to the environment in laboratory itself and periphery, cause
Great public health event.Therefore, in order to ensure the personal safety of staff, when testing to pathogenic microorganism,
Need to set up the checked operation environment of sealed reliable.
In recent years, the threat of strong pathogenic microorganism increasingly sharpens in the world, and what strong pathogenic microorganism was caused
Infection does not generally possess effective treatment and prevention control measure.Therefore, for reducing infection risk, operation can cause the mankind or dynamic
During the strong pathogenic microorganism of thing (very) serious disease, it usually needs possess high biology can carry out completely isolated operation
Carry out in the high-grade biological safe type isolator of security performance.
But, current China mainly adopts the primary protective barrier based on II grade of Biohazard Safety Equipment to carry out pathogenic microorganism
Operation, the operation window of these Biohazard Safety Equipments only prevents harmful substance in cabinet from leaking by air-flow, but the poisonous of its inside has
Evil particulate easily leaks into outside because the improper operation of personnel causes filtered, the environment to experiment place itself and periphery
Pollute, seriously injure the personal safety of experimental work personnel.
Therefore, at present in the urgent need to developing a kind of device, it is strong that it can allow experimental work personnel carry out inside it
The various experimental implementation of pathogenic microorganism, possess good tightness, can be prevented effectively from formed in checked operation process
Harmful substance is diffused into experiment place, prevents the environment to experiment place itself and periphery, and ensures work
The personal safety of personnel.
Content of the invention
In view of this, it is an object of the invention to provide biological safe type glove box type isolator, it can allow experimental work
Personnel carry out the various experimental implementation of strong pathogenic microorganism inside it, possess good tightness, can be prevented effectively from inspection
Test the harmful substance formed in operating process and be diffused into experiment place, prevent the environment in experiment place itself and periphery is made
Become to pollute, and ensure the personal safety of staff, prevent the generation of great public health event, there is great production real
Trample meaning.
For this reason, the invention provides biological safe type glove box type isolator, including the operation casing of airproof, described behaviour
Make the upper and lower both sides of casing and be respectively arranged with the mechanical floor of a hollow and a support；
About the bottom of described mechanical floor two ends be separately installed with a first order exhaust-air filter and one blew
Filter device, the top of described operation casing is connected with described first order exhaust-air filter and powered air-purifying device respectively；
The bottom of described support is provided with a second level exhaust-air filter, described second level exhaust-air filter and institute
State first order exhaust-air filter to be connected, the right-hand member of described second level exhaust-air filter is arranged with a gaseous decontaminant respectively
Outlet is connected with a blower fan；
Before and after described operation casing, both sides operating surface is provided with least two operation gloves；
The left side wall of described operation casing is sealed and installed with appliance doors, and the right side wall of described operation casing is provided with the
One gas-tight door, the airproof transmission bucket that described first gas-tight door is provided with the second gas-tight door with is connected.
Wherein, the right side wall of described mechanical floor is provided with air inlet, and described powered air-purifying device is connected with described air inlet
Logical, when carrying out disinfection to described isolator, described air inlet doubles as disinfectant inlet；
About the top of described operation casing, two ends are respectively arranged with an exhaust outlet and an air outlet, described control box
The top left of body is connected with described first order exhaust-air filter by described exhaust outlet, the top right of described operation casing
End is connected with described powered air-purifying device by described air outlet.
Wherein, the top of described mechanical floor is also equipped with power supply interface and pressure reduction monitoring interface, and described power supply interface runs through
Described mechanical floor, the bottom of described power supply interface with described operation casing top be connected, the bottom of described power supply interface with
One supply socket phase is conductively connected；
The top left inner and outer of described operation casing is respectively provided with an instrument filter, described two instrument mistakes
Filters in series connects, and described pressure reduction monitoring interface is connected with described instrument filter, and described pressure reduction monitoring interface is used for connecting
Differential pressure pickup；
Before and after described operation casing, both sides operating surface is provided with least two gloves holes, and each described gloves hole is pacified
Equipped with a gloves flange, fixed seal connection on each described gloves flange has described operation gloves；
At least two annular grooves are provided with the lateral wall of described gloves flange；
Described operation casing is the casing made using hard transparent material；
The upper rear portion of described support is provided with a protection handle；
The left end outer wall of described transmission bucket is provided with a transmission bucket；
The inner side edge of described appliance doors is inlaid with sealing joint strip, the inner side edge edge of described first gas-tight door
It is embedded with sealing joint strip.
Wherein, described isolator installs two-stage exhaust-air filter, and described two-stage exhaust-air filter includes described first
Level exhaust-air filter and described second level exhaust-air filter, described first order exhaust-air filter includes first order air draft
Filter, the bottom of described first order exhaust-air filter is connected with the exhaust outlet of described operation casing top；
Described second level exhaust-air filter includes second level exhaust-air filter, the left end of described second level exhaust-air filter
Portion has the second upstream aerosol thief hatch；
The downstream air outlet of described first order exhaust-air filter is connected with air pipeline by the second clamping pipe fitting；
The upper and lower ends of described air pipeline are respectively arranged with the first downstream sampling of aerosol mouth and described second upstream gas
Colloidal sol thief hatch；
Second downstream sampling of aerosol mouth, described second downstream are also had on the front of described second level exhaust-air filter
Sampling of aerosol mouth is connected with a filters scan leak detection sampling probe；
The right-hand member of described second level exhaust-air filter is connected with a sterilization checking mouth；
Filter scan leakage detecting device and hermatic door is also included on the exhaust-air filter of the described second level；
Described sterilization checking mouth includes the closure of stop valve and hollow, and described stop valve is connected with closure, described
It is placed with a net cup, described net cup is used for placing the biological indicator of checking Disinfection Effect in closure.
Wherein, described air outlet and air inlet are provided with protection filter screen.
Wherein, the right-hand member of described second level exhaust-air filter passes through pipeline and described gaseous decontaminant outlet and institute respectively
State blower fan to be connected；
Described gaseous decontaminant outlet is located on the right side wall of described support；
It is provided with biological airtight valve between the right-hand member of described second level exhaust-air filter and described blower fan.
Wherein, described isolator also includes a gas depoisoning machine, and described gas depoisoning machine has disinfectant output
Mouth and disinfectant recovery port, described disinfectant delivery outlet is connected with described air inlet by a pipeline, and described disinfectant returns
Close up and be connected with described gaseous decontaminant outlet by a pipeline.
Wherein, described first gas-tight door includes door body and doorframe, and described door body is tightly connected with described doorframe；
One switch handle is provided with the left side wall of described door body, the upper and lower ends of described rotary switch handle set respectively
It is equipped with an eccentric shoe, described eccentric shoe is connected with described door body；
Described door body is articulated by a hinge and described doorframe, and described doorframe is fixed on described operation casing
On right side wall.
Wherein, the edge of described doorframe is arranged at intervals with multiple first draw-in grooves, one end of each described first draw-in groove
It is provided with the first mechanical position limitation；
The edge of described door body is arranged at intervals with multiple second draw-in grooves, and one end of each described second draw-in groove is respectively provided with
There is the second mechanical position limitation；
It is provided with transmission bucket doorframe on the left side wall of described transmission bucket, in described transmission bucket doorframe, be sealedly connected with described the
Two gas-tight doors；
Described first draw-in groove and described transmission bucket doorframe phase clamping, described second draw-in groove and described second gas-tight door phase card
Connect.
The technical scheme being provided from the above present invention, compared with prior art, the invention provides bio-safety
Type glove box type isolator, it can allow experimental work personnel carry out the various experiment behaviour of strong pathogenic microorganism inside it
Make, possess good tightness, the harmful substance formed in checked operation process can be prevented effectively from and be diffused into experiment place,
Prevent to the environment testing place itself and periphery, and ensure the personal safety of staff, prevent great
The generation of public health event, is of great practical significance.
Brief description
The front view of the biological safe type glove box type isolator that Fig. 1 provides for the present invention；
The right view of the biological safe type glove box type isolator that Fig. 2 provides for the present invention；
The top view of the biological safe type glove box type isolator that Fig. 3 provides for the present invention；
In the biological safe type glove box type isolator that Fig. 4 provides for the present invention, the structure of second level exhaust-air filter is shown
It is intended to；
Fig. 5 carries out sterilizing with extraneous gas during gas depoisoning for the biological safe type glove box type isolator that the present invention provides
The connection status schematic diagram of machine；
Fig. 6 is the enlarged diagram of the sterilization checking mouth peripheral structure of I part shown in Fig. 5；
In the biological safe type glove box type isolator that Fig. 7 provides for the present invention, the Facad structure of the first gas-tight door is illustrated
Figure；
In the biological safe type glove box type isolator that Fig. 8 provides for the present invention, the backside structure of the first gas-tight door is illustrated
Figure；
The front view of bucket is transmitted for the present invention in the biological safe type glove box type isolator that Fig. 9 provides；
The left view of bucket is transmitted for the present invention in the biological safe type glove box type isolator that Figure 10 provides；
In figure, 1 is operation casing, and 2 is support, and 3 is powered air-purifying device, and 4 is first order exhaust-air filter, and 5 is the
Two grades of exhaust-air filters, 6 is operation gloves, and 7 is the first gas-tight door, and 8 is transmission bucket, and 9 is appliance doors, and 10 is display screen, 11
For power switch, 12 is biological airtight valve, and 13 is blower fan, and 14 is gaseous decontaminant outlet, and 15 is air pipeline；
16 is air outlet, and 17 is exhaust outlet, and 18 is illuminating lamp, and 19 is power supply interface, and 20 monitor interface for pressure reduction, and 21 is instrument
Table filter, 22 is castor, and 23 is protection handle, and 24 is air inlet, and 25 is the first clamping pipe fitting, and 26 is powered air-purifying device, 27
For first order exhaust-air filter, 28 is the second clamping pipe fitting, and 29 is the first downstream sampling of aerosol mouth, and 30 is second level air draft
Filter, 31 is the second upstream aerosol thief hatch, and 32 is filter scan leakage detecting device, and 33 is hermatic door, and 34 is second time faint breath
Colloidal sol thief hatch, 35 is sterilization checking mouth, and 36 is stop valve, and 37 is closure, and 38 is filters scan leak detection sampling probe, 39
For gloves flange, 40 is annular groove；
41 is switch handle, and 42 is eccentric shoe, and 43 is doorframe, and 44 is hinge, and 45 is interlock, and 46 is the first card
Groove, 47 is the first mechanical position limitation, and 48 is the second draw-in groove, and 49 is the second mechanical position limitation, and 50 is transmission bucket doorframe, and 51 is transmission handle for bucket
Hand, 52 is the second gas-tight door, and 60 is decontamination duct network, and 70 is net cup, and 71 is door body, and 80 is mechanical floor, and 100 is gas depoisoning machine,
101 is disinfectant delivery outlet, and 102 is disinfectant recovery port.
Specific embodiment
In order that those skilled in the art more fully understand the present invention program, below in conjunction with the accompanying drawings with embodiment to this
Invention is described in further detail.
Referring to Fig. 1 to Figure 10, the invention provides biological safe type glove box type isolator, including hollow, airproof
Operation casing 1, described operation casing is respectively arranged with the mechanical floor 80 of a hollow and a support 2 in both sides about 1.
In the present invention, described operation casing 1 is preferably the casing made using hard transparent material, but is not limited to this kind of
Material.
In the present invention, implement, connect for hermetic seal between described operation casing 1 and mechanical floor 80.
In the present invention, implement, the top of multiple bolts and described support 2 is passed through in the bottom of described operation casing 1
Portion is fixedly connected.
In the lump referring to Fig. 2, in the present invention, the bottom circumferentially-spaced of described support 2 is provided with four castors 22, described
The upper rear portion of frame 2 is provided with a protection handle 23, with the isolator facilitating the mobile present invention of experimental work personnel to provide.
In the present invention, about the bottom of described mechanical floor 80, two ends are separately installed with a first order exhaust-air filter
4 and a powered air-purifying device 3, the top of described operation casing 1 respectively with described first order exhaust-air filter 4 and blowing
Filter device 3 is connected.Wherein, described first order exhaust-air filter 4 and powered air-purifying device 3 be respectively used to therein to sucking
Air is filtered.
Implement, there is between described exhaust-air filter 4 and powered air-purifying device 3 display screen 10 and power supply
Switch 11, described display screen 10 and power switch 11 are located at the front of described mechanical floor 80.
Implement, described operation casing 1 top about two ends be respectively arranged with an exhaust outlet 17 and one give
Air port 16, the top left of described operation casing 1 is connected with described first order exhaust-air filter 4 by described exhaust outlet 17
Logical, the top right-hand member of described operation casing 1 is connected with described powered air-purifying device 3 by described air outlet 16.
In the present invention, the bottom of described support 2 is provided with a second level exhaust-air filter 5, described second level row
Wind filter 5 is connected with described first order exhaust-air filter 4.Described second level exhaust-air filter 5 is used for suction
Air therein is filtered, be then discharged out in external environment condition or the external equipment specified in, specifically to through the first order
Air after exhaust-air filter 4 filters is filtered again, and isolator in polluted air exhausting innoxious is effectively ensured.
Referring to Fig. 3, in the present invention, the top of described mechanical floor 80 is provided with illuminating lamp 18, due to described operation casing 1
Made using hard transparent material with mechanical floor 80, therefore, can be to described operation casing 1 and mechanical floor 80 by illuminating lamp 18
Interior space is illuminated, and facilitates experimental work personnel to carry out respective experimental implementation, Enhancement test staff carry to the present invention
For isolator product use feeling.
In the present invention, the top of described mechanical floor 80 is also equipped with power supply interface 19 and pressure reduction monitoring interface 20, described
Power supply interface 19 runs through described mechanical floor 80, and the bottom of described power supply interface 19 is connected with the top of described operation casing 1, institute
State the bottom of power supply interface 19 and a supply socket phase is conductively connected, thus convenient place in the operation casing 1 of isolator
Respective instrument and equipment power supply is provided.
The top left inner and outer of described operation casing 1 is respectively provided with an instrument filter 21, described two instrument
Table filter 21 is connected in series, and described pressure reduction monitoring interface 20 is connected with described instrument filter 21, and described pressure reduction monitoring connects
Mouth 20 is used for connecting differential pressure pickup, such that it is able to effectively prevent differential pressure pickup described in microbiological contamination in isolator.
It should be noted that described differential pressure pickup is a kind of sensor for measuring difference between two pressure, it is generally used for surveying
Measure the pressure reduction between a certain equipment or part rear and front end or two environment adjacent.
In the present invention, referring to Fig. 1 to Fig. 3, described powered air-purifying device 3 includes powered air-purifying device 26, described blows
The bottom of filter 26 is connected with the air outlet 16 at described operation casing 1 top；
The right side wall of described mechanical floor 80 is provided with air inlet 24, and described powered air-purifying device 26 passes through the first clamping pipe fitting 25
It is connected with described air inlet 24, when carrying out disinfection to described isolator, described air inlet 24 doubles as disinfectant inlet；
Implement, described air outlet 16 and air inlet 24 are provided with protection filter screen.Described air inlet 24 also may be used
With when carrying out disinfection to the isolator that the present invention provides, as the inlet of disinfectant.
In the present invention, referring to Fig. 1 to Fig. 3, described isolator installs two-stage exhaust-air filter, described two-stage air draft
Filter device includes described first order exhaust-air filter 4 and described second level exhaust-air filter 5, and described first order air draft is filtered
Device 4 includes first order exhaust-air filter 27, the bottom of described first order exhaust-air filter 27 and described operation casing 1 top
Exhaust outlet 17 is connected；
In the lump referring to Fig. 4, described second level exhaust-air filter 5 includes second level exhaust-air filter 30, the described second level
The left part of exhaust-air filter 30 has the second upstream aerosol thief hatch 31；
The downstream air outlet of described first order exhaust-air filter 27 passes through the second clamping pipe fitting 28 and an air pipeline 15
It is connected, the upper and lower ends of described air pipeline 15 are respectively arranged with the first downstream sampling of aerosol mouth 29 and described second upstream
Sampling of aerosol mouth 31；
Implement, the downstream air outlet of described first order exhaust-air filter 27 by described second clamping pipe fitting 28 with
Described first downstream sampling of aerosol mouth 29 is connected；It should be noted that described first downstream sampling of aerosol mouth 29 also may be used
With the aerosol inlet as second level exhaust-air filter 30.
Implement, in the lump referring to Fig. 4 to Fig. 6, the front of described second level exhaust-air filter 5 also has second
Downstream sampling of aerosol mouth 34, described second downstream sampling of aerosol mouth 34 and filters scan leak detection sampling probe 38 phase
Connect, the windward side of described filters scan leak detection sampling probe 38 is provided with slit-type thief hatch, aerosol sampling apparatus
(such as photometer or corpuscular counter) can be by connecting the second downstream sampling of aerosol mouth 34 and filters scan leak detection sampling
Probe 38 connection, can sample to the air of second level exhaust-air filter 30 outlet air surface, dress is filtered in the air draft of the described second level
The right-hand member putting 5 is also associated with a sterilization checking mouth 35；
Implement, described sterilization checking mouth 35 includes the closure 37 of stop valve 36 and hollow, described stop valve 36
It is connected with closure 37, in described closure 37, is placed with a net cup 70, described net cup 70 is used for placing checking sterilization effect
The biological indicator of fruit.
Implement, described second level exhaust-air filter 5 also includes filter scan leakage detecting device 32 and hermatic door
33.Described scanning leak detection device 32 is used for carrying out sampling of aerosol to second level air draft high efficiency particulate air filter 30 air downstream, thus
Judge that second level exhaust-air filter 30 whether there is leakage, described hermatic door 33 is to change this second level air draft for sealing to filter
The gathering hole of device 30.
In the present invention, implement, the right-hand member of described second level exhaust-air filter 30 passes through pipeline and one respectively
Gaseous decontaminant outlet 14 is connected with a blower fan 13, and described gaseous decontaminant outlet 14 is located at the right side of described support 2
On the wall of side；
It is provided with biological airtight valve 12, for controlling between the right-hand member of described second level exhaust-air filter 30 and described blower fan 13
Make the connection between described second level exhaust-air filter 30 and described blower fan 13 or disconnection.Described blower fan 13 is used for will be through the
This two filters air after filtering of one-level exhaust-air filter 4, second level exhaust-air filter 30 is discharged in external environment.
Implement, referring to Fig. 5, described isolator can also be connected with a gas depoisoning machine 100, described gas
Sterilizing machine 100 is gas fumigation sterilizing machine, described gas depoisoning machine 100 has disinfectant delivery outlet 101 and disinfectant reclaims
Mouth 102, described disinfectant delivery outlet 101 is connected with described air inlet 24 by a decontamination duct 60, and described disinfectant returns
Closing in 102 is connected with described gaseous decontaminant outlet 14 by a decontamination duct 60.
Referring to Fig. 1 to Fig. 3, the front of described operation casing 1 is provided with two gloves holes (figure is slightly), each described gloves hole
On a gloves flange 39 is installed, on each described gloves flange fixed seal connection have one operation gloves 6.Need explanation
, for the present invention, implement, at least two can be respectively provided with by both sides operating surface before and after described operation casing 1
Operation gloves 6, and it is not limited to be shown in two operation gloves of operation casing 1 front setting.
Implement, described gloves flange 39 passes through sealing joint strip, take mechanical compaction mode and described operation casing 1
It is tightly connected.
Implement, referring to Fig. 3, the lateral wall of described gloves flange 39 be provided with least two annular grooves 40,
Described annular groove 40 is used for operation gloves 6 described in fixing seal it is ensured that described gloves flange 39 operates the close of gloves 6 with described
Envelope connection effect, and can be implemented under the air-proof condition not destroying operation casing 1, realize replacement operation gloves.
In the present invention, the left side wall of described operation casing 1 is sealed and installed with appliance doors 9, and described appliance doors 9 adopt
Mechanical compaction mode is sealed connected together with operation casing 1, and takes the mode of outside unlatching.Implement, described
The inner side edge of appliance doors 9 is inlaid with sealing joint strip, thus ensure and operation casing 1 between be tightly connected effect.
In the present invention, in the lump referring to Fig. 7 to Figure 10, the right side wall of described operation casing 1 is provided with the first gas-tight door 7,
Described first gas-tight door 7 is connected with a hollow, airproof transmission bucket 8.
Implement, described first gas-tight door 7 is inwardly opened and is wedge structure, the inner side of described first gas-tight door 7
Edge is inlaid with sealing joint strip.
Implement, described first gas-tight door 7 includes door body 71 and doorframe 43, described door body 71 is close with described doorframe 43
Envelope connects.
Implement, the left side wall of described door body 71 is provided with a switch handle 41, described rotary switch handle
41 upper and lower ends are respectively arranged with an eccentric shoe 42, and described eccentric shoe 42 is connected with described door body 71, thus right
In experimental work personnel, eccentric shoe 42 can be driven to rotate by rotating described switch handle 41, so that described door body
With doorframe 43 lock sealing each other.
Implement, described door body 71 is articulated with described doorframe 43 by a hinge 44, described doorframe 43
It is fixed on the right side wall of described operation casing 1 by flange.
Implement, described doorframe 43 is provided with interlock 45, described interlock is by key switch and latch
Lock composition, when transfer device (as transmission bucket) is installed to gas-tight door 7, key switch is pressed, and now, pin lock is opened, so
Gas-tight door 7 can be opened afterwards；And when not installing external transfer device, key switch is upspring, pin lock is closed, and gas-tight door 7 is no
Method is opened.
Implement, the edge of described doorframe 43 is arranged at intervals with multiple first draw-in grooves 46, and each described first
One end of draw-in groove 46 is provided with the first mechanical position limitation 47；
The edge of described door body 71 is arranged at intervals with multiple second draw-in grooves 48, one end of each described second draw-in groove 48
It is provided with the second mechanical position limitation 49.
In the lump referring to Fig. 9 and Figure 10, the left side wall of described transmission bucket 8 is provided with transmission bucket doorframe 50, described transmission bucket
It is sealedly connected with the second gas-tight door 52 in doorframe 50；
Implement, described first draw-in groove 46 with described transmission bucket doorframe 50 phase clamping and forms integrally, described second
Draw-in groove 48 with the phase clamping of described second gas-tight door 52 and forms one.
Implement, the left end outer wall of described transmission bucket 8 is provided with a transmission bucket 51, facilitates experimental work people
Member carries out rotation process to transmission bucket 8.
For the present invention, specifically install, by described first draw-in groove 46 and the second draw-in groove 48, it is possible to achieve bucket will be transmitted
Doorframe 50 be installed on the doorframe 43 of the first gas-tight door 7, now pass bucket 8 and be installed on described doorframe 43 thus real.At this moment
Wait, by rotating described transmission bucket 51, so that transmission bucket doorframe 50 is close with the doorframe 43 of described first gas-tight door 7
Envelope, and the second gas-tight door 52, the first gas-tight door 7 reach sealing state and formation one.
Additionally, the second gas-tight door 52 is unlocked with transmission bucket 8, by rotating described first gas-tight door 7 (i.e. transfer gate)
Switch handle 41, can open the first gas-tight door 7.Therefore, for the present invention, by the second gas-tight door 52 and the first gas-tight door 7,
Two-door airtight transmission can be realized, facilitate experimental work personnel that the article needing to carry out experimental implementation are passed through transmission bucket 8 and transmit
To the inside of described operation casing 1, can effectively prevent the pollution in the operation casing 1 of isolator in the transmittance process of article
Air leaks to external environment.
In order to be more clearly understood from the use principle of the biological safe type glove box type isolator of present invention offer, below
The original position leak detection flow process and disinfection process being carried out using the present invention is illustrated.
1st, original position (original state when as just installing) the leak detection flow process of exhaust-air filter：When first order air draft is filtered
When device 27 needs to be detected, (at the air inlet 24 of such as powered air-purifying device 3) aerosol generator should be used at its upstream
Send aerosol (finely ground particles), after aerosol is stable, in air intake surface (the i.e. exhaust outlet of first order exhaust-air filter 27
17) using photometer or corpuscular counter, (described photometer and corpuscular counter can be used for gathered in the air aerosol at place
Concentration is calculated), the aerosol concentration from upstream is sampled, then connects photometer or corpuscular counter to
First downstream sampling of aerosol mouth 29 of one-level exhaust-air filter 27 carries out downstream sampling of aerosol, and (upstream and downstream may also be employed one
Corpuscular counter)；
After sampling terminates, according to the aerosol concentration percentage of upstream and downstream, calculate the filtration of first order exhaust-air filter 27
Efficiency, the filtration rank (i.e. the levels of the standard of filter efficiency) nominal with first order exhaust-air filter 27 is contrasted, thus sentencing
Disconnected filter and its installation frame whether there is leakage, the filtration grade nominal without reaching first order exhaust-air filter 27
Not, then there is leakage in explanation filter or installation frame, conversely, explanation does not leak.
For the present invention, when second level exhaust-air filter 30 needs to be detected, aerosol generator is connected to the
First downstream sampling of aerosol mouth 29 (as the aerosol inlet of second level exhaust-air filter) of one-level exhaust-air filter 27,
Then sending aerosol, after aerosol is stable, then connecting corpuscular counter to upstream gas colloidal sol thief hatch 31, thus entering
Row upstream sampling of aerosol, after reaching the concentration that the relevant criterion pre-setting requires, corpuscular counter is connected to lower faint breath
Colloidal sol thief hatch 34, is sampled and is moved described filters scan leak detection sampling probe 38, to second level exhaust-air filter 30
And its frame installed is scanned hunting leak, judge that second level exhaust-air filter 30 and its installation frame whether there is leakage.If
During scanning sample, doubtful leak source is detected, be then attached to be fixed sampling at doubtful leak source position, if collect
Population continues to increase, then explanation filter has leak source.
2nd, the disinfection process of isolator：Before sterilization, biological airtight valve 12 is closed so that the air draft of the described second level is filtered
Device 30 and described blower fan 13 separated, when then adopting gas circulation disinfection way, will be defeated for the disinfectant of gas depoisoning machine 100
Outlet 101 is connected to air inlet 24 (doubling as disinfectant inlet) by pipeline, and the disinfectant of gas depoisoning machine 100 is returned
Closing in 102 connects to gaseous decontaminant outlet 14, thus forming the sterilization loop of closed loop.Meanwhile, checking sterilization will be also used for
The biological indicator (described biological indicator can be for example bacillus subtilis bacterium piece) of effect is placed into sterilization checking mouth 35
In interior net cup 70, close closure 37, open stop valve 36, be then turned on gas depoisoning machine 100, thus sending gas depoisoning
Agent, and powered air-purifying device 26, first order exhaust-air filter 27, second level air draft filtration internal to the operation casing 1 of isolator
Device 30 carries out sterilizing in situ.
When using gas one cross formula disinfection way when, then need by gaseous decontaminant outlet 14 by decontamination duct network connect to
The exhaust system in place laboratory or external environment；After sterilization terminates, take off the decontamination duct network of isolator, open biological airtight valve
12, open the isolator ventilating system pair being made up of first order exhaust-air filter 27, second level exhaust-air filter 30 and blower fan 13
Remaining disinfectant is purged, and after purging terminates, takes out biological indicator and carries out culture checking Disinfection Effect, then entirely sterilize
Flow process completes.
Understood based on above technical scheme, the invention has the advantages that：
1st, the isolator that the present invention provides possesses high biological safety protection performance.The structure of this isolator and accessory equipment are all
Using gas-tight design, integrally there is good mechanical isolation performance；Normal operating condition, is negative pressure in isolator, simultaneously by the
The isolator ventilating system of one-level exhaust-air filter 27, second level exhaust-air filter 30 and blower fan 13 composition can be in isolator gloves
Occur automatically improving exhaust air rate under breakage or dropping situations, make breakage or glove port air keep being inwardly directed flowing, effectively
In reduction isolator, leakage of aerosol is to the risk of isolator external environment condition；Isolator supply air system installs efficient powered air-purifying
Device, exhaust system installs first order exhaust-air filter 27,30 two high efficiency particulate air filters of second level exhaust-air filter altogether, is provided with former
Position leak detection and the measure of sterilization, can effectively improve its biological safety.
2nd, the isolator that the present invention provides is mounted with two-door airtight transfer device, can not destroy in article transmittance process
Box body tightness, can effectively prevent contaminated air from leaking into isolator external environment.
3rd, the isolator that the present invention provides has good visuality.This isolator casing adopts rigid plastics material system
Make, there is good translucency.
4th, the isolator that the present invention provides has good operation ease.This isolating device is provided with many chemically-resistants and disappears
The flexible gauntlet of toxic agent corrosion, is easy to operate；It is provided with the supply socket of 220V in cofferdam, can be placement in isolator
Instrument and equipment provides power supply.
The biological safe type glove box type isolator providing for the present invention, can effectively meet strong pathogenic microorganism behaviour
The bio-safety made requires, and it possesses the high-efficiency air filtering performance of high security, poisonous within isolator effectively to prevent
Particulates emission is filtered and leak into outside, and possess good casing tightness and stable vacuum cavitations, to realize
Mechanical seal and the protection of negative pressure dual resisteance, its all operations is required to realize by gloves, and in the transmittance process of article
It is unable to the tightness of damage containment device casing, meanwhile, possess and the technical measures of overall disinfection are carried out to meet biology to isolator
Safety requirements.
In sum, compared with prior art, the biological safe type glove box type isolator that the present invention provides, it is permissible
Allow experimental work personnel carry out the various experimental implementation of strong pathogenic microorganism inside it, possess good tightness, can
It is prevented effectively from the harmful substance formed in checked operation process and is diffused into experiment place, prevent to experiment place itself and week
The environment on side, and ensure the personal safety of staff, prevent the generation of great public health event, there is weight
Big production practices meaning.
The above is only the preferred embodiment of the present invention it is noted that ordinary skill people for the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (9)
1. biological safe type glove box type isolator is it is characterised in that include the operation casing (1) of airproof, described control box
Up and down both sides are respectively arranged with the mechanical floor (80) of a hollow and a support (2) to body (1)；
About the bottom of described mechanical floor (80), two ends are separately installed with a first order exhaust-air filter (4) and an air-supply
Filter (3), the top of described operation casing (1) is filled with described first order exhaust-air filter (4) and powered air-purifying respectively
Put (3) to be connected；
The bottom of described support (2) is provided with a second level exhaust-air filter (5), described second level exhaust-air filter
(5) it is connected with described first order exhaust-air filter (4), the right-hand member of described second level exhaust-air filter (5) is respectively with one
Individual gaseous decontaminant outlet (14) is connected with a blower fan (13)；
Before and after described operation casing (1), both sides operating surface is provided with least two operation gloves (6)；
The left side wall of described operation casing (1) is sealed and installed with an appliance doors (9), the right side wall peace of described operation casing (1)
The airproof transmission bucket being provided with the second gas-tight door (52) with one equipped with the first gas-tight door (7), described first gas-tight door (7)
(8) it is connected.
2. isolator as claimed in claim 1 is it is characterised in that the right side wall of described mechanical floor (80) is provided with air inlet
(24), described powered air-purifying device (3) is connected with described air inlet (24), when carrying out disinfection to described isolator, described
Air inlet (24) doubles as disinfectant inlet；
About the top of described operation casing (1), two ends are respectively arranged with an exhaust outlet (17) and an air outlet (16), institute
The top left stating operation casing (1) is connected with described first order exhaust-air filter (4) by described exhaust outlet (17), institute
The top right-hand member stating operation casing (1) is connected with described powered air-purifying device (3) by described air outlet (16).
3. isolator as claimed in claim 2 is it is characterised in that the top of described mechanical floor (80) is also equipped with power supply interface
(19) and pressure reduction monitoring interface (20), described power supply interface (19) runs through described mechanical floor (80), described power supply interface (19)
Bottom is connected with the top of described operation casing (1), and the bottom of described power supply interface (19) is mutually conductive with a supply socket
Connect；
The top left inner and outer of described operation casing (1) is respectively provided with an instrument filter (21), described two instrument
Table filter (21) is connected in series, and described pressure reduction monitoring interface (20) is connected with described instrument filter (21), described pressure reduction
Monitoring interface (20) is used for connecting differential pressure pickup；
Before and after described operation casing (1), both sides operating surface is provided with least two gloves holes, and each described gloves hole is pacified
Equipped with a gloves flange (39), fixed seal connection on each described gloves flange has described operation gloves (6)；
At least two annular grooves (40) are provided with the lateral wall of described gloves flange (39)；
Described operation casing (1) is the casing made using hard transparent material；
The upper rear portion of described support (2) is provided with protection handle (23)；
The left end outer wall of described transmission bucket (8) is provided with transmission bucket (51)；
The inner side edge of described appliance doors (9) is inlaid with sealing joint strip, the inner side edge of described first gas-tight door (7)
It is inlaid with sealing joint strip.
4. isolator as claimed in claim 2 or claim 3 is it is characterised in that described isolator installs two-stage exhaust-air filter, institute
State two-stage exhaust-air filter and include described first order exhaust-air filter (4) and described second level exhaust-air filter (5), institute
State first order exhaust-air filter (4) and include first order exhaust-air filter (27), the bottom of described first order exhaust-air filter (27)
Portion is connected with the exhaust outlet (17) at described operation casing (1) top；
Described second level exhaust-air filter (5) includes second level exhaust-air filter (30), described second level exhaust-air filter
(30) left part has the second upstream aerosol thief hatch (31)；
The downstream air outlet of described first order exhaust-air filter (27) passes through the second clamping pipe fitting (28) and air pipeline (15) phase
Connection；
The upper and lower ends of described air pipeline (15) are respectively arranged with the first downstream sampling of aerosol mouth (29) and described second
Faint breath colloidal sol thief hatch (31)；
Second downstream sampling of aerosol mouth (34) also had on the front of described second level exhaust-air filter (5), described second
Downstream sampling of aerosol mouth (34) is connected with filters scan leak detection sampling probe (38)；
The right-hand member of described second level exhaust-air filter (5) is connected with sterilization checking mouth (35)；
Filter scan leakage detecting device (32) and hermatic door (33) are also included on described second level exhaust-air filter (5)；
Described sterilization checking mouth (35) includes closure (37), described stop valve (36) and the closure of stop valve (36) and hollow
(37) it is connected, in described closure (37), is placed with a net cup (70), described net cup (70) is used for placing checking sterilization effect
The biological indicator of fruit.
5. isolator as claimed in claim 4 is it is characterised in that be provided with described air outlet (16) and air inlet (24)
Protection filter screen.
6. isolator as claimed in claim 1 is it is characterised in that the right-hand member of described second level exhaust-air filter (30) leads to respectively
Piping is connected with described gaseous decontaminant outlet (14) and described blower fan (13)；
Described gaseous decontaminant outlet (14) is located on the right side wall of described support (2)；
It is provided with biological airtight valve (12) between the right-hand member of described second level exhaust-air filter (30) and described blower fan (13).
7. the isolator as any one of claim 1 to 6 is it is characterised in that also include a gas depoisoning machine
(100), described gas depoisoning machine (100) have disinfectant delivery outlet (101) and disinfectant recovery port (102), described sterilization
Agent delivery outlet (101) is connected with described air inlet (24) by a pipeline, and described disinfectant recovery port (102) passes through one
Pipeline is connected with described gaseous decontaminant outlet (14).
8. the isolator as any one of claim 1 to 6 is it is characterised in that described first gas-tight door (7) includes door body
(71) and doorframe (43), described door body (71) and described doorframe (43) are tightly connected；
One switch handle (41) is provided with the left side wall of described door body (71), up and down the two of described rotary switch handle (41)
End is respectively arranged with an eccentric shoe (42), and described eccentric shoe (42) is connected with described door body (71)；
Described door body (71) is articulated with described doorframe (43) by a hinge (44), and described doorframe (43) is fixed on institute
State on the right side wall of operation casing (1).
9. isolator as claimed in claim 8 it is characterised in that the edge of described doorframe (43) be arranged at intervals with multiple
First draw-in groove (46), one end of each described first draw-in groove (46) is provided with the first mechanical position limitation (47)；
The edge of described door body (71) is arranged at intervals with multiple second draw-in grooves (48), and the one of each described second draw-in groove (48)
End is provided with the second mechanical position limitation (49)；
Transmission bucket doorframe (50) is provided with the left side wall of described transmission bucket (8), is tightly connected in described transmission bucket doorframe (50)
There is described second gas-tight door (52)；
Described first draw-in groove (46) and described transmission bucket doorframe (50) phase clamping, described second draw-in groove (48) is airtight with described second
Door (52) phase clamping.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610819092.5A CN106393181B (en) | 2016-09-13 | 2016-09-13 | Biological safe type glove box type isolator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610819092.5A CN106393181B (en) | 2016-09-13 | 2016-09-13 | Biological safe type glove box type isolator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106393181A true CN106393181A (en) | 2017-02-15 |
| CN106393181B CN106393181B (en) | 2018-12-25 |
Family
ID=57999206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610819092.5A Active CN106393181B (en) | 2016-09-13 | 2016-09-13 | Biological safe type glove box type isolator |
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| Country | Link |
|---|---|
| CN (1) | CN106393181B (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109512541A (en) * | 2017-09-19 | 2019-03-26 | 中国人民解放军军事科学院军事医学研究院微生物流行病研究所 | Medium and small animal organism aerosol mouth and nose exposure system |
| CN109719759A (en) * | 2017-10-31 | 2019-05-07 | 北京慧荣和科技有限公司 | Glove box |
| CN110227821A (en) * | 2019-07-04 | 2019-09-13 | 成都德力斯实业有限公司 | The flexible connection of particular atmosphere environment is maintained in 3D printing cabin |
| CN112873282A (en) * | 2021-01-13 | 2021-06-01 | 杭州市疾病预防控制中心 | Portable pathogen detection operation protective housing |
| CN112957501A (en) * | 2020-12-25 | 2021-06-15 | 杭州中赢生物医疗科技有限公司 | Safety cabinet sterilization device based on biological experiment equipment and use method thereof |
| CN113008467A (en) * | 2021-02-24 | 2021-06-22 | 军事科学院系统工程研究院卫勤保障技术研究所 | Air cleaner integrality on-line monitoring device |
| CN113350955A (en) * | 2021-06-01 | 2021-09-07 | 昱辰实验室系统科技(苏州)有限公司 | Aerosol processor |
| CN113504339A (en) * | 2021-06-02 | 2021-10-15 | 湖南中净生物科技有限公司 | Method for testing smoke inactivation effect of tertiary virus |
| CN114833873A (en) * | 2022-04-15 | 2022-08-02 | 中国核电工程有限公司 | Sealing door device and glove box |
| CN116872256A (en) * | 2023-06-28 | 2023-10-13 | 湖北中循医疗用品实业有限公司 | Shielding glove box |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005084835A1 (en) * | 2004-03-04 | 2005-09-15 | Skan Ag | Arrangement for conducting air and regulating pressure in an insulator with a work which is protected against the external environment |
| US6974197B1 (en) * | 2001-02-06 | 2005-12-13 | The United States Of America As Represented By The Secretary Of The Army | Portable glovebox and filtration system |
| CN101524051A (en) * | 2009-04-13 | 2009-09-09 | 中国人民解放军第二军医大学 | Multi-functional medium-sized animal breeding isolation system |
| CN102059160A (en) * | 2010-10-20 | 2011-05-18 | 中国人民解放军军事医学科学院微生物流行病研究所 | Biological safety protection cabin |
| CN204502606U (en) * | 2015-03-23 | 2015-07-29 | 中国人民解放军军事医学科学院卫生装备研究所 | Tuyere-type efficiency leakage detecting type air draft air filtering apparatus |
| CN206105903U (en) * | 2016-09-13 | 2017-04-19 | 中国人民解放军军事医学科学院卫生装备研究所 | Box isolator of bio -safety type gloves |
-
2016
- 2016-09-13 CN CN201610819092.5A patent/CN106393181B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6974197B1 (en) * | 2001-02-06 | 2005-12-13 | The United States Of America As Represented By The Secretary Of The Army | Portable glovebox and filtration system |
| WO2005084835A1 (en) * | 2004-03-04 | 2005-09-15 | Skan Ag | Arrangement for conducting air and regulating pressure in an insulator with a work which is protected against the external environment |
| CN101524051A (en) * | 2009-04-13 | 2009-09-09 | 中国人民解放军第二军医大学 | Multi-functional medium-sized animal breeding isolation system |
| CN102059160A (en) * | 2010-10-20 | 2011-05-18 | 中国人民解放军军事医学科学院微生物流行病研究所 | Biological safety protection cabin |
| CN204502606U (en) * | 2015-03-23 | 2015-07-29 | 中国人民解放军军事医学科学院卫生装备研究所 | Tuyere-type efficiency leakage detecting type air draft air filtering apparatus |
| CN206105903U (en) * | 2016-09-13 | 2017-04-19 | 中国人民解放军军事医学科学院卫生装备研究所 | Box isolator of bio -safety type gloves |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109512541A (en) * | 2017-09-19 | 2019-03-26 | 中国人民解放军军事科学院军事医学研究院微生物流行病研究所 | Medium and small animal organism aerosol mouth and nose exposure system |
| CN109719759A (en) * | 2017-10-31 | 2019-05-07 | 北京慧荣和科技有限公司 | Glove box |
| CN110227821A (en) * | 2019-07-04 | 2019-09-13 | 成都德力斯实业有限公司 | The flexible connection of particular atmosphere environment is maintained in 3D printing cabin |
| CN112957501A (en) * | 2020-12-25 | 2021-06-15 | 杭州中赢生物医疗科技有限公司 | Safety cabinet sterilization device based on biological experiment equipment and use method thereof |
| CN112873282A (en) * | 2021-01-13 | 2021-06-01 | 杭州市疾病预防控制中心 | Portable pathogen detection operation protective housing |
| CN112873282B (en) * | 2021-01-13 | 2023-10-03 | 杭州市疾病预防控制中心 | Movable pathogen detection operation protective box |
| CN113008467A (en) * | 2021-02-24 | 2021-06-22 | 军事科学院系统工程研究院卫勤保障技术研究所 | Air cleaner integrality on-line monitoring device |
| CN113350955A (en) * | 2021-06-01 | 2021-09-07 | 昱辰实验室系统科技(苏州)有限公司 | Aerosol processor |
| CN113504339A (en) * | 2021-06-02 | 2021-10-15 | 湖南中净生物科技有限公司 | Method for testing smoke inactivation effect of tertiary virus |
| CN114833873A (en) * | 2022-04-15 | 2022-08-02 | 中国核电工程有限公司 | Sealing door device and glove box |
| CN116872256A (en) * | 2023-06-28 | 2023-10-13 | 湖北中循医疗用品实业有限公司 | Shielding glove box |
| CN116872256B (en) * | 2023-06-28 | 2024-03-19 | 湖北中循医疗用品实业有限公司 | Shielding glove box |
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