CN107625892A - A kind of Chinese medicine preparation based on dendrobium candidum - Google Patents
A kind of Chinese medicine preparation based on dendrobium candidum Download PDFInfo
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- CN107625892A CN107625892A CN201710909651.6A CN201710909651A CN107625892A CN 107625892 A CN107625892 A CN 107625892A CN 201710909651 A CN201710909651 A CN 201710909651A CN 107625892 A CN107625892 A CN 107625892A
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Abstract
A kind of Chinese medicine preparation based on dendrobium candidum, composition of raw materials include:25~45 parts of dendrobium candidum extract solution, 12~30 parts of cordyceps sinensis, 10~26 parts of wild jujube, 8~19 parts of American Ginseng, 5~19 parts of pilose antler, 7~22 parts of mulberries, 3~18 parts of Radix Codonopsis, 12~20 parts of Radix Angelicae Sinensis, 5~18 parts of black soya bean, 3~11 parts of almond, 2~11 parts of dried orange peel, 3~19 parts of lotus leaf, 12~19 parts of dried scallop, 11~19 parts of the fleece-flower root, 3~17 parts of sealwort.The Chinese medicine preparation of the present invention can strengthen activities of antioxidant enzymes in blood, promote spleen lymphocyte proliferation, and suppresses the release of proinflammatory inflammation factor, suppresses the activation of NK Κ b Inflammatory Pathways, so as to have the function that ovarian senescence resistance lesion.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, more particularly to a kind of Chinese medicine preparation based on dendrobium candidum, belong to medicine
Field.
Background technology
Aging is a kind of complicated natural phenomena in life, and it is the internal types of functionality activity after matrix is reached maturity
The process that progressive declines occurs.
On aging theory and up to more than 300 kinds of hypothesis, mainly have free-radical oxidation theory, immunologic derangement theory,
Big cerebral senility damage theory, hypoendocrinism theory etc..Free-radical oxidation theory thinks living caused by metabolism in life cycle
Damage caused by property oxygen composition can cause aging phenomenon.With age, the system of defense function of free radical is begun to decline,
Internal superoxide dismutase is gradually reduced, and MDA gradually rises, and causes a large amount of unsaturated fat acid oxidases, causes cell wide
General property damage, so as to promote body aging.Immunologic derangement theory thinks immune response increase of the elderly to autoantigen, and right
The immune response of exogenous antigen reduces.The aging of immune system is mainly point of immune organ thymus gland and marrow hemopoietic stem cells
The degeneration of vigor, cell differentiation is secreted, cellular immune function is shown as and humoral immune function declines.So regulation immunologic function can
Contribute to anti-aging.Cell death thinks that cell death is the importance of aging with aging theory, including necrosis and apoptosis.
Just there is apoptosis amount adult rats early stage, increases with the age, and Apoptosis speed is accelerated, and the removing to apoptotic cell slows down,
This phenomenon is particularly evident in aged rats.Apoptosis is probably the important original for causing nerve cell death during brain aging
Cause.Hypoendocrinism theory thinks that body growth, development, maturation and aging and multicellular organism neuroendocrine function have
Very close relationship.Increasing with the age, Endocrine Levels gradually reduce, wherein it is the most obvious with female hormone decline, swash
Plain horizontal reduction influences normal cell activity, so as to cause aging.Women post menopausal complementing estrogen is horizontal, can effectively prolong
Slow osteoporosis, atherosclerosis, in addition, the growth hormone in body fluid, testosterone and sulfuric acid dehydroisoandrosterone are also with the age
Increase and rapid decrease, by supplementing certain hormone in short term, muscle strength, skin elasticity and bone density etc. can be improved.
Dendrobium candidum is orchid family perennial herb aerial plant, is the distinctive precious Chinese medicine in China, as one of yin tonics,
Its nourishing effects is very notable, is known as the title of " a thousand pieces of gold grass ", is more referred to as " giant panda of plant kingdom " by International Plant circle.In recent years
It is increasing as the health product of development of raw materials using dendrobium candidum, and dendrobium candidum strictly makes wild resource to growing environment requirement
Increasingly it is rare.At present, dendrobium candidum is induced by ball stem, propagation, differentiation seedling are formed and the culture skill such as growth, test tube transplantation of seedlings
Art realizes artificial cultivation.Dendrobium candidum contains a variety of chemical compositions, mainly including polysaccharide, amino acid, alkaloid etc..
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation based on dendrobium candidum.
In order to achieve the above objects and other related objects, technical scheme provided by the invention is:One kind is based on dendrobium candidum
Chinese medicine preparation, the composition of raw materials of the Chinese medicine preparation based on dendrobium candidum includes the component of following parts by weight:
Preferably technical scheme is:The composition of raw materials of the Chinese medicine preparation based on dendrobium candidum includes following parts by weight
Component:
Because above-mentioned technical proposal is used, the present invention this have the advantage that compared with prior art:
(1) Chinese medicine preparation of the present invention based on dendrobium candidum can strengthen activities of antioxidant enzymes in blood, promote spleen
Lymphopoiesis, and suppress the release of proinflammatory inflammation factor, suppress the activation of NK-Kb Inflammatory Pathways, declined so as to reach anti-ovary
The effect of old lesion.
(2) the method for the invention can fully extract the active polysaccharide in dendrobium candidum, retain it to greatest extent
The activity of antioxidant groups.
Embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this implementation
Content disclosed by example understands other advantages and effect of the present invention easily.
Embodiment 1:A kind of Chinese medicine preparation based on dendrobium candidum
A kind of Chinese medicine preparation based on dendrobium candidum, by weight, the composition of raw materials of the Chinese medicine preparation includes:Iron sheet
25 parts of dendrobium extract, 12 parts of cordyceps sinensis, 10 parts of wild jujube, 8 parts of American Ginseng, 5 parts of pilose antler, 7 parts of mulberries, 3 parts of Radix Codonopsis, Radix Angelicae Sinensis 12
Part, 5 parts of black soya bean, 3 parts of almond, 2 parts of dried orange peel, 3 parts of lotus leaf, 12 parts of dried scallop, 11 parts of the fleece-flower root, 3 parts of sealwort.
The formulation of the Chinese medicine preparation based on dendrobium candidum is oral liquid.
Preparation method comprises the following steps:
(1) fresh dendrobium candidum is weighed, cleans, cut section, into juice extractor, by several times plus appropriate amount of water is distilled, squeezes the juice, with 200
Mesh filter-cloth filtering, after filtrate is heated to boiling, 4 DEG C of preservations are placed in after being maintained at slight boiling condition lower 3 minutes, obtain squeezeding juice.
(2) squeezeding juice for taking step (1) to obtain, it is 50mg/mL to be diluted with water to solid content, heating and refluxing extraction 2 times,
During heating and refluxing extraction, each micro-boiling 0.5 hour (i.e. squeezeding juice carries out refluxing extraction under slight boiling condition), merge extract solution,
Concentrate is obtained with Rotary Evaporators concentrated extracting solution, the water of 1.5 times of weight is added in the most backward concentrate, was placed
At night, the filtrate obtained after next day filtering is dendrobium candidum extract solution.
(3) cordyceps sinensis, wild jujube, American Ginseng and pilose antler are taken, the ethanol that the volume fraction for adding 3 times of volumes is 50%, backflow
Extraction 1 time, 0.5 hour every time, merge ethanol extract, the filtrate being filtrated to get is condensed into the leaching that relative density is 1.25 again
Cream, relative density are measured when 60 DEG C, and ethanol is reclaimed in concentration process.
(4) almond and dried orange peel are taken, adds the water of 5 times of volumes to soak 0.5 hour, steam distillation 0.5 hour, obtains condensate liquid
And the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating.
(5) dregs of a decoction obtained by step (4) are mixed with mulberries, Radix Codonopsis, Radix Angelicae Sinensis, black soya bean, lotus leaf, dried scallop, the fleece-flower root, sealwort
Close, and the decocting for adding 5 times of volumes thereto is boiled 1 time, 1 hour every time, collecting decoction, filtrate is obtained after filtering.
(6) aqueous solution that step (4) is collected is merged with the filtrate obtained by step (5), is condensed into relative density as 1.25
Clear cream, what relative density was surveyed when 60 DEG C.
(7) medicinal extract that clear cream, the step (3) obtained dendrobium candidum extract solution, step (6) obtains merges, and adds quality point
Number is 0.05% sorb aqueous acid, then is adjusted to decoction with water, filling through stirring evenly, and is gone out using boiling method or flowing steam method
Bacterium, you can the Chinese medicine preparation based on dendrobium candidum is made, the formulation of this Chinese medicine preparation is oral liquid.The addition of sorb aqueous acid
Measure as the 2% of Chinese medicine preparation gross mass.
Embodiment 2:A kind of Chinese medicine preparation based on dendrobium candidum
A kind of Chinese medicine preparation based on dendrobium candidum, by weight, the composition of raw materials of the Chinese medicine preparation includes:Iron sheet
35 parts of dendrobium extract, 25 parts of cordyceps sinensis, 22 parts of wild jujube, 16 parts of American Ginseng, 14 parts of pilose antler, 18 parts of mulberries, 14 parts of Radix Codonopsis, when
Return 16 parts, 13 parts of black soya bean, 8 parts of almond, 7 parts of dried orange peel, 13 parts of lotus leaf, 15 parts of dried scallop, 17 parts of the fleece-flower root, 14 parts of sealwort.
The formulation of the Chinese medicine preparation based on dendrobium candidum is oral liquid.
Preparation method comprises the following steps:
(1) fresh dendrobium candidum is weighed, cleans, cut section, into juice extractor, by several times plus appropriate amount of water is distilled, squeezes the juice, with 200
Mesh filter-cloth filtering, after filtrate is heated to boiling, 4 DEG C of preservations are placed in after being maintained at slight boiling condition lower 4 minutes, obtain squeezeding juice.
(2) squeezeding juice for taking step (1) to obtain, it is 120mg/mL to be diluted with water to solid content, heating and refluxing extraction 4 times,
In heating and refluxing extraction, each micro-boiling 1.2 hours (i.e. squeezeding juice carries out refluxing extraction under slight boiling condition), merge extraction
Liquid, concentrate is obtained with Rotary Evaporators concentrated extracting solution, the water of 2 times of weight is added in the most backward concentrate, was placed
At night, the filtrate obtained after next day filtering is dendrobium candidum extract solution.
(3) cordyceps sinensis, wild jujube, American Ginseng and pilose antler are taken, the ethanol that the volume fraction for adding 12 times of volumes is 70%, backflow
Extraction 4 times, 2 hours every time, merge ethanol extract, the filtrate being filtrated to get is condensed into the medicinal extract that relative density is 1.3, phase again
Density is measured in 60 DEG C when, ethanol is reclaimed in concentration process.
(4) almond and dried orange peel are taken, adds the water of 16 times of volumes to soak 20 hours, steam distillation 8 hours, obtain condensate liquid and
The dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating.
(5) dregs of a decoction obtained by step (4) are mixed with mulberries, Radix Codonopsis, Radix Angelicae Sinensis, black soya bean, lotus leaf, dried scallop, the fleece-flower root, sealwort
Close, and the decocting for adding 15 times of volumes thereto is boiled 3 times, 2.5 hours every time, collecting decoction, filtrate is obtained after filtering.
(6) aqueous solution that step (4) is collected is merged with the filtrate obtained by step (5), it is 1.3 to be condensed into relative density
Clear cream, what relative density was surveyed when 60 DEG C.
(7) medicinal extract that clear cream, the step (3) obtained dendrobium candidum extract solution, step (6) obtains merges, and adds quality point
Number is 0.12% sorb aqueous acid, then is adjusted to decoction with water, filling through stirring evenly, and is gone out using boiling method or flowing steam method
Bacterium, you can the Chinese medicine preparation based on dendrobium candidum is made, the formulation of this Chinese medicine preparation is oral liquid.The addition of sorb aqueous acid
Measure as the 3% of Chinese medicine preparation gross mass.
Embodiment 3:A kind of Chinese medicine preparation based on dendrobium candidum
A kind of Chinese medicine preparation based on dendrobium candidum, by weight, the composition of raw materials of the Chinese medicine preparation includes:Iron sheet
45 parts of dendrobium extract, 30 parts of cordyceps sinensis, 26 parts of wild jujube, 19 parts of American Ginseng, 19 parts of pilose antler, 22 parts of mulberries, 18 parts of Radix Codonopsis, when
Return 20 parts, 18 parts of black soya bean, 11 parts of almond, 11 parts of dried orange peel, 19 parts of lotus leaf, 19 parts of dried scallop, 19 parts of the fleece-flower root, 17 parts of sealwort.
The formulation of the Chinese medicine preparation based on dendrobium candidum is oral liquid.
Preparation method comprises the following steps:
(1) fresh dendrobium candidum is weighed, cleans, cut section, into juice extractor, by several times plus appropriate amount of water is distilled, squeezes the juice, with 200
Mesh filter-cloth filtering, after filtrate is heated to boiling, 4 DEG C of preservations are placed in after being maintained at slight boiling condition lower 5 minutes, obtain squeezeding juice.
(2) squeezeding juice for taking step (1) to obtain, it is 200mg/mL to be diluted with water to solid content, heating and refluxing extraction 5 times,
In heating and refluxing extraction, each micro-boiling 1.5 hours (i.e. squeezeding juice carries out refluxing extraction under slight boiling condition), merge extraction
Liquid, concentrate is obtained with Rotary Evaporators concentrated extracting solution, the water of 3 times of weight is added in the most backward concentrate, was placed
At night, the filtrate obtained after next day filtering is dendrobium candidum extract solution.
(3) cordyceps sinensis, wild jujube, American Ginseng and pilose antler are taken, the ethanol that the volume fraction for adding 15 times of volumes is 95%, backflow
Extraction 6 times, 3 hours every time, merging ethanol extract, the filtrate being filtrated to get is condensed into the medicinal extract that relative density is 1.35 again,
Relative density is measured when 60 DEG C, and ethanol is reclaimed in concentration process.
(4) almond and dried orange peel are taken, adds the water of 10 times of volumes to soak 24 hours, steam distillation 12 hours, obtains condensate liquid
And the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating.
(5) dregs of a decoction obtained by step (4) are mixed with mulberries, Radix Codonopsis, Radix Angelicae Sinensis, black soya bean, lotus leaf, dried scallop, the fleece-flower root, sealwort
Close, and the decocting for adding 20 times of volumes thereto is boiled 6 times, 3 hours every time, collecting decoction, filtrate is obtained after filtering.
(6) aqueous solution that step (4) is collected is merged with the filtrate obtained by step (5), is condensed into relative density as 1.35
Clear cream, what relative density was surveyed when 60 DEG C.
(7) medicinal extract that clear cream, the step (3) obtained dendrobium candidum extract solution, step (6) obtains merges, and adds quality point
Number is 0.15% sorb aqueous acid, then is adjusted to decoction with water, filling through stirring evenly, and is gone out using boiling method or flowing steam method
Bacterium, you can the Chinese medicine preparation based on dendrobium candidum is made, the formulation of this Chinese medicine preparation is oral liquid.The addition of sorb aqueous acid
Measure as the 2.5% of Chinese medicine preparation gross mass.
The test of pesticide effectiveness is carried out to the Chinese medicine preparation of the present invention based on dendrobium candidum, it is specific as follows:
1st, animal
Kunming mice, SPF levels, 18-22g, female.
2nd, medicine
The Chinese medicine preparation based on dendrobium candidum that embodiment 1~3 prepares.
3rd, positive drug
Estradiol valerate tablet, lot number:27A2, Bayer HealthCare Co.
4th, test method:
Mouse peritoneal injection chloraldurate (dosage 200mg/kg) is anaesthetized, and abdomen position is fixed, and cuts off dorsal midline diamond wool,
It is local that iodine is gone with iodine tincture disinfection and 75% alcohol 1/3rd under trunk, 1cm stringer otch is about near backbone, point
After skin, make two otch at each 1~2cm in both sides, after separating muscle layer, pull out faint yellow cellulite, one can be found
The thin-line-shaped irregular tissue in yellowish pink is ovary;Under to connect thick tubular tissue be cornua uteri, cut off ovary, tissue pushed back
Abdominal cavity, sterilized after suturing muscle layer and skin layer otch, postoperative muscle injection novocillin 120,000 unit/only, conventinal breeding,
For experiment.
Art the latter moon (allows animal to recover state, and eliminates hormone retaining in vivo), be randomly divided into castration model group,
1~3 group of estradiol group, embodiment, totally 5 groups, every group 12, separately take and be only used as sham-operation group with batch mouse 12.Estradiol is administered
Dosage:0.17mg/kg;Chinese medicine preparation dosage based on dendrobium candidum is 0.2mg/kg.Each group gives relative medicine by body weight, false
Operation group and castration model group give isometric distilled water, 1 time a day, continuous 1 month.
Biochemical indicator detects:After last dose terminates, animal fasting can't help water 12 hours, and orbital venous plexus takes blood,
3500rpm centrifuges 15 minutes isolated serum, using kit measurement serum calcium, phosphorus, alkaline phosphatase, superoxide dismutase
Enzyme and mda content.
Internal organs processing and histopathological examination:After experiment terminates, cervical dislocation puts to death mouse.Uterus is taken, is being divided
Analyse and calculate organ coefficient (organ weights/body weight × ‰), more each group difference on balance after precise weighing.Uterus after weighing
Fixed immediately with 10% formalin, check pathological section is done after HE dyeing.Lesion is divided into level Four by light and heavy degree:Nothing (-),
Gently (+), in (++), again (+++), be calculated as 0,1,2,3 point respectively, pathological observation project be epithelial lesion, body of gland change, inflammation it is anti-
Should, fibroplasia and blood vessel hyperplasia phenomenon etc. 5.
5th, statistical analysis method:
Measured value mean ± standard deviation, pathological score are represented with median (first quartile, the 3rd quartile)
(M (Q1, Q3)), makees one-way analysis of variance with SPSS20.0 statistical softwares, compares when variance is neat between group using LSD methods, variance
Non-parametric test is used when uneven, the Kruskal-Wsllis H that pathological score is compared using multiple independent samples are examined, P<
0.05 thinks statistically significant.
6th, experimental result
(1) to serum Ca, the influence of P, AKP, SOD and MDA content
Compared with sham-operation group, castration model group serum Ca, P content are decreased obviously, compared with castration model group, this hair
The bright preparation administration group has the adjustment effect without degree to each index, has improve serum Ca, P, AKP content
Effect, show that Chinese medicine preparation of the present invention has certain adjustment effect to calcium phosphorus balance.
Compared with sham-operation group, castration model group SOD vigor is decreased obviously, and MDA contents are significantly raised;With castration model group
Compare, Chinese medicine preparation of the present invention can significantly raised SOD vigor, show that Chinese medicine preparation of the present invention can strengthen body
Oxidation resistance, it is effectively improved radical metabolism exception.
(2) organ coefficient and pathological examination results
As shown in table 1, compared with sham-operation group, castration model group Uterine coefficient significantly reduces;Compared with castration model group,
Estradiol group and Chinese medicine preparation group of the present invention are remarkably improved Uterine coefficient.
Influence (‰, χ ± s, n=12) of the table 1 to castration female Mouse Uterus coefficient
Group | Uterine coefficient |
Sham-operation group | 3.88±1.68 |
Castration model group | 0.55±0.22## |
Estradiol group | 1.78±0.45** |
Embodiment 1 | 1.67±0.12 |
Embodiment 2 | 1.69±0.13 |
Embodiment 3 | 1.72±0.14 |
Note:Compared with sham-operation group,##P<0.01;Compared with castration model group, * * P<0.01.
As shown in table 2, sham-operation group intra-uterine membranous layer is thicker, the bending of interior membrane cavity, and intimal epithelium hyperplasia is in high column, body of gland
It is hyperplasia, intensive.Castration model group uterine wall is substantially thinning, and interior membrane cavity is small and straight, intimal epithelium doll shape, body of gland atrophy.With going
Potential model group is compared, Chinese medicine preparation group uterus wall thickening of the present invention, and interior membrane cavity increase, epithelium part is in the form of a column.
The castration female Mouse Uterus pathology damage degree grade form (M (Q1, Q3), n=6) of table 2
Note:Compared with sham-operation group,##P<0.01;Compared with castration model group, * * P<0.01.
Embodiment 4:A kind of Chinese medicine preparation based on dendrobium candidum
A kind of Chinese medicine preparation based on dendrobium candidum, under the composition of raw materials of the Chinese medicine preparation based on dendrobium candidum includes
The component of row parts by weight:
Preparation method comprises the following steps:
The first step:Squeezed the juice after fresh dendrobium candidum is mixed with water, then with 200 mesh filtered through gauze, obtained filtrate is micro-
Boiling preserves under the conditions of being placed in 4 DEG C after 3.5 minutes, obtains squeezeding juice;
Second step:It is 75mg/mL that the squeezeding juice is diluted with water into solid content, then heating and refluxing extraction 3 times, is being added
During circumfluence distillation, each micro-boiling 1.2 hours, merge extract solution, next concentrating the extract solution with Rotary Evaporators obtains
Concentrate, the water of 2.5 times of weight is most added in the concentrate backward, is stood overnight, the filtrate obtained after next day filtering is iron
Skin dendrobium extract;
3rd step:Cordyceps sinensis, wild jujube, American Ginseng and pilose antler are taken, the second that the volume fraction for adding 11.5 times of volumes is 65%
Alcohol, refluxing extraction 5 times, 3 hours every time, merge ethanol extract, the filtrate obtained after filtering is condensed into relative density and is again
1.31 medicinal extract, relative density measure when 60 DEG C;
4th step:Almond and dried orange peel are taken, adds the water of 13 times of volumes to soak 20 hours, steam distillation 5 hours, is condensed
Liquid and the dregs of a decoction, the condensate liquid obtain volatile oil and the aqueous solution after water-oil separating;
5th step:By the dregs of a decoction obtained by the 4th step and mulberries, Radix Codonopsis, Radix Angelicae Sinensis, black soya bean, lotus leaf, dried scallop, the fleece-flower root, sealwort
Mixing, and the decocting for adding 7 times of volumes thereto is boiled 3 times, and 2 hours every time, filtrate is obtained after collecting decoction filtering;
6th step:The aqueous solution collected by 4th step is merged with the filtrate obtained by the 5th step, being condensed into relative density is
1.25 clear cream, relative density measure when 60 DEG C;
7th step:Dendrobium candidum extract solution, medicinal extract are merged with clear cream, the sorbic acid for adding mass fraction to be 0.08% is water-soluble
Liquid, then decoction is adjusted to water, through stirring evenly, the Chinese medicine preparation based on dendrobium candidum is produced after filling and sterilization steps.Sorbic acid
The addition of the aqueous solution is the 3% of Chinese medicine preparation gross mass.
As described above is only to explain the preferred embodiments of the invention, is not intended to tool to do any shape to the present invention
Limitation in formula, therefore all have any modification or change for making the relevant present invention under identical spirit, it should all wrap
Include the invention is intended to the category protected.
Claims (2)
- A kind of 1. Chinese medicine preparation based on dendrobium candidum, it is characterised in that:The raw material of the Chinese medicine preparation based on dendrobium candidum Formula includes the component of following parts by weight:The parts by weight of dendrobium candidum extract solution 25~45;The parts by weight of cordyceps sinensis 12~30;The parts by weight of wild jujube 10~26;The parts by weight of American Ginseng 8~19;The parts by weight of pilose antler 5~19;The parts by weight of mulberries 7~22;The parts by weight of Radix Codonopsis 3~18;The parts by weight of Radix Angelicae Sinensis 12~20;The parts by weight of black soya bean 5~18;The parts by weight of almond 3~11;The parts by weight of dried orange peel 2~11;The parts by weight of lotus leaf 3~19;The parts by weight of dried scallop 12~19;The parts by weight of the fleece-flower root 11~19;The parts by weight of sealwort 3~17.
- 2. the Chinese medicine preparation according to claim 1 based on dendrobium candidum, it is characterised in that:It is described based on dendrobium candidum The composition of raw materials of Chinese medicine preparation includes the component of following parts by weight:The parts by weight of dendrobium candidum extract solution 35;The parts by weight of cordyceps sinensis 25;The parts by weight of wild jujube 22;The parts by weight of American Ginseng 16;The parts by weight of pilose antler 14;The parts by weight of mulberries 18;The parts by weight of Radix Codonopsis 14;The parts by weight of Radix Angelicae Sinensis 16;The parts by weight of black soya bean 13;The parts by weight of almond 8;The parts by weight of dried orange peel 7;The parts by weight of lotus leaf 13;The parts by weight of dried scallop 15;The parts by weight of the fleece-flower root 17;The parts by weight of sealwort 14.
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CN112021566A (en) * | 2020-08-24 | 2020-12-04 | 浙江红石梁集团天台山乌药有限公司 | Dendrobium officinale, American ginseng and radix ophiopogonis granules |
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CN1436560A (en) * | 2002-02-07 | 2003-08-20 | 阮沸翔 | Kidney and spleen invigorating Chinese medicine beverage for delaying senility |
CN105748947A (en) * | 2016-05-23 | 2016-07-13 | 吴子平 | Dendrobium officinale compound capsule and preparation method thereof |
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CN112021566A (en) * | 2020-08-24 | 2020-12-04 | 浙江红石梁集团天台山乌药有限公司 | Dendrobium officinale, American ginseng and radix ophiopogonis granules |
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