CN107614699A - 用于检测凝集的方法以及用于实践该方法的组合物 - Google Patents

用于检测凝集的方法以及用于实践该方法的组合物 Download PDF

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CN107614699A
CN107614699A CN201680031621.3A CN201680031621A CN107614699A CN 107614699 A CN107614699 A CN 107614699A CN 201680031621 A CN201680031621 A CN 201680031621A CN 107614699 A CN107614699 A CN 107614699A
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antigen
polynucleotide
sample
dna
cases
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P·鲁宾逊
C-T·蔡
C·贝尔托齐
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University of California San Diego UCSD
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/6844—Nucleic acid amplification reactions
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
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    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/117—Modifications characterised by incorporating modified base
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

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  • Food Science & Technology (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201680031621.3A 2015-04-17 2016-04-15 用于检测凝集的方法以及用于实践该方法的组合物 Pending CN107614699A (zh)

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US201562149324P 2015-04-17 2015-04-17
US62/149,324 2015-04-17
PCT/US2016/027906 WO2016168711A1 (en) 2015-04-17 2016-04-15 Methods for detecting agglutination and compositions for use in practicing the same

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US (2) US11149296B2 (enExample)
EP (2) EP4123031A1 (enExample)
JP (1) JP6822973B2 (enExample)
CN (1) CN107614699A (enExample)
AU (1) AU2016249392A1 (enExample)
BR (1) BR112017022329A2 (enExample)
CA (1) CA2982998A1 (enExample)
EA (1) EA201792289A1 (enExample)
WO (1) WO2016168711A1 (enExample)
ZA (1) ZA201707114B (enExample)

Cited By (9)

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CN109142730A (zh) * 2018-06-14 2019-01-04 郑州大学第附属医院 一种肺癌标志物抗-psip1自身抗体及其应用
CN111323590A (zh) * 2020-03-19 2020-06-23 福建省立医院 抗TIF1γ-IgA与抗TIF1γ-IgG作为联合诊断标志物在肺癌诊断中的应用
CN111499724A (zh) * 2020-04-15 2020-08-07 上海领潮生物新材料有限公司 一种s-腺苷同型半胱氨酸-鸡卵白蛋白偶联物的制备方法
WO2021185357A1 (zh) * 2020-03-20 2021-09-23 北京良芯生物科技发展有限公司 一种用于检测人类免疫缺陷病毒hiv1/2抗体的蛋白芯片及其制备方法
CN114316016A (zh) * 2021-12-14 2022-04-12 江苏浩欧博生物医药股份有限公司 一种Jo-1抗原生物素化的方法及抗Jo-1抗体检测试剂盒
CN115060912A (zh) * 2022-06-23 2022-09-16 南京浦光生物科技有限公司 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法
CN115397464A (zh) * 2020-04-24 2022-11-25 美国西门子医学诊断股份有限公司 用于使用抗人免疫球蛋白抗体的抗微生物血清学测定的组合物、试剂盒和方法
CN116125076A (zh) * 2022-12-30 2023-05-16 广州医科大学 检测桥粒蛋白的试剂在制备肝纤维化的检测产品中的应用
CN118667920A (zh) * 2024-07-30 2024-09-20 北京华诺奥美基因生物科技有限公司 一种基于微流控的低丰度生物标志物的检测试剂盒、检测方法及其应用

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CN106591436A (zh) * 2016-11-24 2017-04-26 湖南大学 用于检测人体内低丰度抗体的邻位连接核酸探针与试剂盒及其制备方法
CA3058451A1 (en) 2017-03-30 2018-10-04 The Board Of Trustees Of The Leland Stanford Junior University Multiplex isotype-specific antibody detection
JP7675441B2 (ja) * 2019-05-06 2025-05-13 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 移植拒絶反応の非ｈｌａマーカー
US20230142838A1 (en) * 2021-11-08 2023-05-11 Summit Biolabs, Inc. Devices and methods for nucleic acid extraction-free sti pathogen testing
EP4389913A1 (en) * 2022-12-23 2024-06-26 Universität Heidelberg A pcr-elisa analogous antibody-free method for detecting a target nucleic acid in a sample

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CN101410530A (zh) * 2003-04-18 2009-04-15 贝克顿·迪金森公司 免疫-扩增
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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109142730B (zh) * 2018-06-14 2021-04-23 郑州大学第一附属医院 一种肺癌标志物抗-psip1自身抗体及其应用
CN109142730A (zh) * 2018-06-14 2019-01-04 郑州大学第附属医院 一种肺癌标志物抗-psip1自身抗体及其应用
CN111323590B (zh) * 2020-03-19 2022-04-22 福建省立医院 抗TIF1γ-IgA与抗TIF1γ-IgG作为联合诊断标志物在肺癌诊断中的应用
CN111323590A (zh) * 2020-03-19 2020-06-23 福建省立医院 抗TIF1γ-IgA与抗TIF1γ-IgG作为联合诊断标志物在肺癌诊断中的应用
WO2021185357A1 (zh) * 2020-03-20 2021-09-23 北京良芯生物科技发展有限公司 一种用于检测人类免疫缺陷病毒hiv1/2抗体的蛋白芯片及其制备方法
CN111499724A (zh) * 2020-04-15 2020-08-07 上海领潮生物新材料有限公司 一种s-腺苷同型半胱氨酸-鸡卵白蛋白偶联物的制备方法
CN115397464A (zh) * 2020-04-24 2022-11-25 美国西门子医学诊断股份有限公司 用于使用抗人免疫球蛋白抗体的抗微生物血清学测定的组合物、试剂盒和方法
CN114316016A (zh) * 2021-12-14 2022-04-12 江苏浩欧博生物医药股份有限公司 一种Jo-1抗原生物素化的方法及抗Jo-1抗体检测试剂盒
CN114316016B (zh) * 2021-12-14 2023-11-10 江苏浩欧博生物医药股份有限公司 一种Jo-1抗原生物素化的方法及抗Jo-1抗体检测试剂盒
CN115060912A (zh) * 2022-06-23 2022-09-16 南京浦光生物科技有限公司 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法
CN115060912B (zh) * 2022-06-23 2024-02-02 南京浦光生物科技有限公司 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法
CN116125076A (zh) * 2022-12-30 2023-05-16 广州医科大学 检测桥粒蛋白的试剂在制备肝纤维化的检测产品中的应用
CN118667920A (zh) * 2024-07-30 2024-09-20 北京华诺奥美基因生物科技有限公司 一种基于微流控的低丰度生物标志物的检测试剂盒、检测方法及其应用
CN118667920B (zh) * 2024-07-30 2024-11-12 北京华诺奥美基因生物科技有限公司 一种基于微流控的低丰度生物标志物的检测试剂盒、检测方法及其应用

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EP3283638A1 (en) 2018-02-21
EP3283638A4 (en) 2018-09-12
JP6822973B2 (ja) 2021-01-27
WO2016168711A1 (en) 2016-10-20
US11149296B2 (en) 2021-10-19
JP2018512862A (ja) 2018-05-24
US20210403978A1 (en) 2021-12-30
US20180100181A1 (en) 2018-04-12
CA2982998A1 (en) 2016-10-20
ZA201707114B (en) 2019-02-27
EP4123031A1 (en) 2023-01-25
BR112017022329A2 (pt) 2018-07-17
EP3283638B1 (en) 2022-06-08
AU2016249392A1 (en) 2017-11-16
EA201792289A1 (ru) 2018-04-30
US12054768B2 (en) 2024-08-06

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