CN107614004B - 抗微生物肽及其使用方法 - Google Patents

抗微生物肽及其使用方法 Download PDF

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Publication number
CN107614004B
CN107614004B CN201680025771.3A CN201680025771A CN107614004B CN 107614004 B CN107614004 B CN 107614004B CN 201680025771 A CN201680025771 A CN 201680025771A CN 107614004 B CN107614004 B CN 107614004B
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antimicrobial
composition
amino acid
pharmaceutical composition
peptide
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Chinese (zh)
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CN107614004A (zh
Inventor
杰西·杰尼斯
L·爱德华·克莱门斯
亨利·W·洛佩兹
乔治·R·马丁
凯瑟琳·伍德伯恩
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Riptide Bioscience Inc
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Riptide Bioscience Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
CN201680025771.3A 2015-03-23 2016-03-23 抗微生物肽及其使用方法 Active CN107614004B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211040273.XA CN115475232A (zh) 2015-03-23 2016-03-23 抗微生物肽及其使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562137206P 2015-03-23 2015-03-23
US62/137,206 2015-03-23
PCT/US2016/023801 WO2016154328A2 (en) 2015-03-23 2016-03-23 Antimicrobial peptides and methods of use thereof

Related Child Applications (1)

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CN202211040273.XA Division CN115475232A (zh) 2015-03-23 2016-03-23 抗微生物肽及其使用方法

Publications (2)

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CN107614004A CN107614004A (zh) 2018-01-19
CN107614004B true CN107614004B (zh) 2022-12-06

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CN202211040273.XA Pending CN115475232A (zh) 2015-03-23 2016-03-23 抗微生物肽及其使用方法

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US (2) US10017542B2 (enExample)
EP (2) EP3903823A3 (enExample)
JP (2) JP6964577B2 (enExample)
KR (1) KR20180002618A (enExample)
CN (2) CN107614004B (enExample)
AU (2) AU2016235147B2 (enExample)
CA (1) CA2981705A1 (enExample)
WO (1) WO2016154328A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3903823A3 (en) * 2015-03-23 2022-02-23 Riptide Bioscience, Inc. Antimicrobial peptides and methods of use thereof
GB201812972D0 (en) 2018-08-09 2018-09-26 Univ Oxford Innovation Ltd Cell-penetrating peptides
GB201812980D0 (en) 2018-08-09 2018-09-26 Univ Oxford Innovation Ltd Cell-penetrating peptides
US10413584B1 (en) * 2018-08-29 2019-09-17 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
EP3844297A4 (en) * 2018-08-29 2022-08-31 Riptide Bioscience, Inc. PEPTIDES WITH IMMUNOMODULATORY PROPERTIES
US20200102356A1 (en) * 2018-10-01 2020-04-02 NMC Inc. Compositions and Methods for the Treatment of Huanglongbing (HLB) aka Citrus Greening in Citrus Plants
EP3866826B1 (en) * 2018-10-19 2025-12-10 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same
US10548944B1 (en) * 2018-10-19 2020-02-04 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same
WO2020115494A1 (en) 2018-12-07 2020-06-11 Oxford University Innovation Limited Linkers
WO2020199202A1 (zh) * 2019-04-04 2020-10-08 林翰佳 碳量子点及其用途
CN110305193B (zh) * 2019-07-18 2021-10-08 河南科技大学 一种抗牙龈卟啉单胞菌多肽及应用
JP7717797B2 (ja) * 2021-09-03 2025-08-04 深▲セン▼千越生物科技有限公司 抗菌ペプチド又はペプチド誘導体、置換体及びその組成物、製造方法及び応用
CN114989254B (zh) * 2022-06-17 2023-11-03 中山大学 一种多肽及其设计方法和在制备抑制具核梭杆菌产品或预防结直肠癌药物中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012866A1 (en) * 1989-04-10 1990-11-01 Louisiana State University And Agricultural And Mechanical College Lytic peptides, use for growth, infection and cancer
EP0781347A1 (en) * 1994-07-22 1997-07-02 Demeter Biotechnologies, Ltd. Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same
CN101448851A (zh) * 2006-05-16 2009-06-03 德玛根股份公司 改进的抗微生物肽

Family Cites Families (16)

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JPH03504501A (ja) * 1988-05-27 1991-10-03 マゲイニン　サイエンセス　インコーポレーテッド 両親媒性ペプチドとその用途
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
JPH08134075A (ja) * 1994-11-02 1996-05-28 Yamanouchi Pharmaceut Co Ltd 新規なカルバペネム誘導体
AU720405B2 (en) * 1996-02-16 2000-06-01 Regents Of The University Of California, The Antimicrobial peptides and methods of use
EP0932413A1 (en) * 1996-10-04 1999-08-04 Demegen, Inc. Method for treatment of immunodeficiency virus infection
US6680058B1 (en) * 1997-09-03 2004-01-20 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions and methods for contraception in or sterilization of mammals
JP2003509010A (ja) * 1999-05-31 2003-03-11 ノボザイムス アクティーゼルスカブ ペプチドのスクリーニング方法
US6432415B1 (en) * 1999-12-17 2002-08-13 Axrix Laboratories, Inc. Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces
WO2004033715A1 (en) * 2002-10-09 2004-04-22 Novozymes A/S A method for screening for an antimicrobial polypeptide
CA2655448C (en) * 2005-12-22 2016-09-06 Novabiotics Limited Cyclic antimicrobial peptides
AU2007229275B2 (en) * 2006-03-23 2013-02-07 Agriculture Victoria Services Pty Ltd Antimicrobial protein
US7288622B1 (en) * 2006-09-19 2007-10-30 Issar Pharmaceuticals Pvt Ltd Composition for treatment of burns and wounds
US7803755B2 (en) * 2006-12-21 2010-09-28 Jesse Jaynes Molecules for the treatment and prevention of fungal diseases
US9163066B2 (en) * 2010-06-29 2015-10-20 Agromed Llc Antimicrobial lytic peptides
EP2468856A1 (en) * 2010-12-23 2012-06-27 Lysando Aktiengesellschaft Antimicrobial Agents
EP3903823A3 (en) * 2015-03-23 2022-02-23 Riptide Bioscience, Inc. Antimicrobial peptides and methods of use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012866A1 (en) * 1989-04-10 1990-11-01 Louisiana State University And Agricultural And Mechanical College Lytic peptides, use for growth, infection and cancer
EP0781347A1 (en) * 1994-07-22 1997-07-02 Demeter Biotechnologies, Ltd. Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same
CN101448851A (zh) * 2006-05-16 2009-06-03 德玛根股份公司 改进的抗微生物肽

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Improving on nature"s defenses: optimization & high throughput screening of antimicrobial peptides;D Raventós等;《Comb Chem High Throughput Screen》;20050508;第219-233页 *

Also Published As

Publication number Publication date
AU2016235147B2 (en) 2019-09-19
US10017542B2 (en) 2018-07-10
CA2981705A1 (en) 2016-09-29
US20160296594A1 (en) 2016-10-13
EP3274472A4 (en) 2018-12-05
WO2016154328A2 (en) 2016-09-29
EP3274472A2 (en) 2018-01-31
AU2019222918A1 (en) 2019-09-19
EP3903823A3 (en) 2022-02-23
US20190071470A1 (en) 2019-03-07
AU2016235147A1 (en) 2017-10-26
JP2018512454A (ja) 2018-05-17
CN115475232A (zh) 2022-12-16
AU2019222918B2 (en) 2021-10-21
CN107614004A (zh) 2018-01-19
JP2021054842A (ja) 2021-04-08
JP6964577B2 (ja) 2021-11-10
KR20180002618A (ko) 2018-01-08
JP7267251B2 (ja) 2023-05-01
EP3274472B1 (en) 2020-09-23
EP3903823A2 (en) 2021-11-03

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