CN107594227A - Fish feed, feed addictive and preparation method thereof - Google Patents

Fish feed, feed addictive and preparation method thereof Download PDF

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Publication number
CN107594227A
CN107594227A CN201711037392.9A CN201711037392A CN107594227A CN 107594227 A CN107594227 A CN 107594227A CN 201711037392 A CN201711037392 A CN 201711037392A CN 107594227 A CN107594227 A CN 107594227A
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CN
China
Prior art keywords
parts
fish feed
aminobutyric acid
rich
feed additive
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Pending
Application number
CN201711037392.9A
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Chinese (zh)
Inventor
林金新
董旺
董少英
陶勇
黄建忠
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Dr Nong (fujian) Biotechnology Co Ltd
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Dr Nong (fujian) Biotechnology Co Ltd
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Priority to CN201711037392.9A priority Critical patent/CN107594227A/en
Publication of CN107594227A publication Critical patent/CN107594227A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • Y02A40/818Alternative feeds for fish, e.g. in aquacultures

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)

Abstract

The present invention relates to a kind of fish feed additive rich in gamma aminobutyric acid, including following raw material:6 10 parts of 20 30 parts of gamma aminobutyric acid, 58 parts of superoxide dismutase, 15 parts of Lavender, 15 parts of grape-kernel oil, 24 parts of chamomile essential oil, 5 10 parts of vitamin C, 5 10 parts of radix pseudostellariae, 35 parts of vitamin E, 25 parts of folic acid, 8 12 parts of antibacterial peptide, 18 22 parts of starch and hydroxypropyl methyl cellulose.The invention further relates to a kind of fish feed rich in gamma aminobutyric acid and a kind of preparation method of the fish feed additive rich in gamma aminobutyric acid.The fish feed additive rich in gamma aminobutyric acid of the present invention, which has, effectively alleviates high density shoal of fish stress reaction, improves fish feed intake, improves daily gain, reduces antibiotic usage amount, reduction disease incident and the advantages of the death rate.

Description

Fish feed, feed addictive and preparation method thereof
Technical field
The present invention relates to feed additive technology, more particularly to a kind of fish feed rich in γ-aminobutyric acid, feed add Add agent and preparation method thereof.
Background technology
The stress reaction of fish is fish body to a kind of non-specific caused by the supernormal stimulus of the various envirment factors in inside and outside Property physiological reaction so that organism adaptation beyond normal physiological adjustable range environmental change requirement.Should but too strong or long Sharp reaction can produce injury to body, cause the decline of fish feed intake, metabolic disorder, body growth to develop slow, fertility Decline, immunity function is low, morbidity and mortality improve.How to alleviate and stress reduce fish to the damage that fish body is brought and support The economic loss grown, healthy fish is cultivated significant.
It is more at present to be alleviated using Vc, resisting stress medicine etc. in order to overcome the stress reaction that fish high-density breeding is brought Harm, but these medicine anti-stress effect unobvious or have remain surely, therefore develop new, efficient, safe resisting stress Additive is imperative.
The content of the invention
The technical problems to be solved by the invention are:There is provided it is a kind of can effectively alleviate that fish high-density breeding brings stress The fish feed rich in γ-aminobutyric acid, the feed addictive and preparation method thereof of reaction.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is:
A kind of fish feed additive rich in γ-aminobutyric acid, including following raw material:γ-aminobutyric acid 20- 30 parts, superoxide dismutase 5-8 parts, Lavender 1-5 parts, grape-kernel oil 1-5 parts, chamomile essential oil 2-4 parts, vitamin C5-10 parts, radix pseudostellariae 5-10 parts, vitamin E 3-5 parts, folic acid 2-5 parts, antibacterial peptide 8-12 parts, starch 18-22 parts and hydroxypropyl Methylcellulose 6-10 parts.
A kind of fish feed rich in γ-aminobutyric acid, including above-mentioned fish feed additive.
A kind of preparation method of the fish feed additive rich in γ-aminobutyric acid, by above-mentioned fish feed additive Each raw material ratio by weight mixed, then in mixed mixed material add water until submergence mixed material, It is granulated and is air-dried successively again, obtains the fish feed additive.
The beneficial effects of the present invention are:
In the fish feed and fish feed additive of the present invention, its raw material is rich in γ-aminobutyric acid, and by above-mentioned Component proportion designs, and can reduce serum cortisol and serum glucose level, effectively alleviates high density shoal of fish stress reaction, improves Fish feed intake, improve daily gain, reduce antibiotic usage amount, reduce disease incident and the death rate, can be used as fish efficiently, The resisting stress additive of safety;Meanwhile each raw material is green raw material, there is the advantages of environment-friendly.
Embodiment
To describe the technology contents of the present invention, the objects and the effects in detail, it is explained below in conjunction with embodiment.
The design of most critical of the present invention is:The fish feed rich in γ-aminobutyric acid of design above-mentioned raw materials proportioning adds Add agent.
The present invention provides a kind of fish feed additive rich in γ-aminobutyric acid, including following raw material:γ- Aminobutyric acid 20-30 parts, superoxide dismutase 5-8 parts, Lavender 1-5 parts, grape-kernel oil 1-5 parts, chamomile essential oil 2-4 parts, vitamin C 5-10 parts, radix pseudostellariae 5-10 parts, vitamin E 3-5 parts, folic acid 2-5 parts, antibacterial peptide 8-12 parts, starch 18- 22 parts and hydroxypropyl methyl cellulose 6-10 parts.
A kind of fish feed rich in γ-aminobutyric acid, including above-mentioned fish feed additive.
A kind of preparation method of the fish feed additive rich in γ-aminobutyric acid, by above-mentioned fish feed additive Each raw material ratio by weight mixed, then in mixed mixed material add water until submergence mixed material, It is granulated and is air-dried successively again, obtains the fish feed additive.
It was found from foregoing description, the beneficial effects of the present invention are:
In the fish feed and fish feed additive of the present invention, its raw material is rich in γ-aminobutyric acid, and by above-mentioned Component proportion designs, and can reduce serum cortisol and serum glucose level, effectively alleviates high density shoal of fish stress reaction, improves Fish feed intake, improve daily gain, reduce antibiotic usage amount, reduce disease incident and the death rate, can be used as fish efficiently, The resisting stress additive of safety;Meanwhile each raw material is green raw material, there is the advantages of environment-friendly.
In the present invention, γ-aminobutyric acid is a kind of nonprotein amino acid for playing nerve in animal body and calming, and is Most important inhibitory aminoacid mediator in central nervous system.As a kind of functional amino class feed addictive, raising Application in material production also has been to be concerned by more and more people, and it, which has, significantly improves the feed intake of animal, reduces answering for animal Swash (caused by heat stress and cold stress and nutrient imbalance etc. various stress), hence it is evident that promote the growth of animal, repair damaged intestine Deng effect.
The mechanism of action of γ-aminobutyric acid in the present invention is:
(1) Gabanergic reduces body CCK secretions, improves NPY secretions, suppresses α-MSH secretions, so as to improve CAMP concentration, stimulating growth hormone secretion, improve the speed of growth.
(2) Gabanergic promotes the secretion of epiphysin and serotonine in animal body, hence it is evident that improves animal body Interior thyrotropic hormone is horizontal, so as to effectively solve it is various stress problem.
(3) Gabanergic improves the activity of the esterified enzyme of glucose phosphate, makes the movable vigorous of brain cell, can increase The concentration of acetylcholine, so as to effectively improve feed intake and growth promotion.
(4) γ-aminobutyric acid can suppress the integration of brain stem respiratory center, slow down respiratory rate, slow down animal and exist Hot during heat stress pants, so as to effectively solve the heat stress of animal.
In the fish feed additive rich in γ-aminobutyric acid of the present invention:
Further, the starch is 20 parts.
Further, the hydroxypropyl methyl cellulose is 8 parts.
In the fish feed rich in γ-aminobutyric acid of the present invention:
Further, the addition of the fish feed additive is the 0.5-2 ‰ of the gross weight of fish feed.
In the preparation method of the fish feed additive rich in γ-aminobutyric acid of the present invention:
Further, first radix pseudostellariae is crushed, then carries out above-mentioned married operation.
Embodiments of the invention one are:
The fish feed rich in γ-aminobutyric acid of the present embodiment, fish feed addition per ton are rich in γ-aminobutyric acid 0.5 kilogram of fish feed additive.
The preparation method of fish feed additive rich in γ-aminobutyric acid is:
20 parts of γ-aminobutyric acid, 5 parts of superoxide dismutase, 1 part of Lavender, grape pip are weighed in parts by weight 1 part of oil, 2 parts of chamomile essential oil, 5 parts of vitamin C, 5 parts of radix pseudostellariae fine powder (60 mesh sieves are crossed after grinding), 3 parts of vitamin E, folic acid 2 Part, 8 parts of antibacterial peptide, 20 parts of starch and 8 parts of hydroxypropyl methyl cellulose.After well mixed, add appropriate amount of deionized water, then carry out Extruder grain waves granulation, after air-drying, obtains the fish feed additive for being rich in γ-aminobutyric acid.
Embodiments of the invention two are:
The fish feed rich in γ-aminobutyric acid of the present embodiment, fish feed addition per ton are rich in γ-aminobutyric acid 2 kilograms of fish feed additive.
The preparation method of fish feed additive rich in γ-aminobutyric acid is:
30 parts of γ-aminobutyric acid, 8 parts of superoxide dismutase, 5 parts of Lavender, grape pip are weighed in parts by weight 5 parts of oil, 4 parts of chamomile essential oil, 10 parts of vitamin C, 10 parts of radix pseudostellariae fine powder (60 mesh sieves are crossed after grinding), 5 parts of vitamin E, leaf 8 parts of 5 parts of acid, 12 parts of antibacterial peptide, 20 parts of starch and hydroxypropyl methyl cellulose.After well mixed, add appropriate amount of deionized water, then Carry out extruder grain or wave granulation, after air-drying, obtain the fish feed additive for being rich in γ-aminobutyric acid.
Embodiments of the invention three are:
The fish feed rich in γ-aminobutyric acid of the present embodiment, fish feed addition per ton are rich in γ-aminobutyric acid 1.5 kilograms of fish feed additive.
The preparation method of fish feed additive rich in γ-aminobutyric acid is:
25 parts of γ-aminobutyric acid, 7 parts of superoxide dismutase, 3 parts of Lavender, grape pip are weighed in parts by weight 3 parts of oil, 3 parts of chamomile essential oil, 9 parts of vitamin C, 9 parts of radix pseudostellariae fine powder (60 mesh sieves are crossed after grinding), 4 parts of vitamin E, folic acid 3 Part, 9 parts of antibacterial peptide, 20 parts of starch and 8 parts of hydroxypropyl methyl cellulose.After well mixed, add appropriate amount of deionized water, then carry out Extruder grain waves granulation, after air-drying, obtains the fish feed additive for being rich in γ-aminobutyric acid.
Embodiments of the invention 4-6 is:
The component of the only fish feed additive rich in γ-aminobutyric acid is different from above-described embodiment one.Embodiment 4-6's Concrete component proportioning is shown in Table 1.
Table 1
Add the embodiment 1-6 addition of the fish feed rich in γ-aminobutyric acid respectively in crucian cultivation feed per ton 1 kilogram of agent, it is continuous respectively to feed crucian (500) 5 weeks, and gather and obtain cortisol, serum glucose, daily ingestion amount (500 Take the average value of the daily ingestion amount of every fish), average daily gain, morbidity and mortality;Embodiment 1-6 feed addictives are fed Cortisol, serum glucose, daily ingestion amount, average daily gain, the morbidity and mortality obtained after foster crucian round respectively Body average value, as addition group 1;
The above-mentioned crucian cultivation for the fish feed additive rich in γ-aminobutyric acid for being not added with embodiment 1-6 is taken simultaneously Feed, continuously feed crucian (500) 5 weeks, and gather acquisition cortisol, serum glucose, (500 take every to daily ingestion amount The average value of the daily ingestion amount of fish), average daily gain, morbidity and mortality;As a control group 1.
The cortisol of above-mentioned addition group 1 and control group 1, serum glucose, daily ingestion amount, average daily gain, the incidence of disease and The result of the death rate see the table below 2.
Table 2
The fish feed rich in γ-aminobutyric acid for adding embodiment 1-6 respectively in large yellow croaker breeding feed per ton adds Add 1 kilogram of agent, it is continuous respectively to feed large yellow croaker (500) 8 weeks, and gather and obtain cortisol, serum glucose, rate of body weight gain, feeding Expect efficiency, morbidity and mortality;By the cortisol obtained after the large yellow croaker of embodiment 1-6 feed addictives nursing, serum Portugal Grape sugar, rate of body weight gain, feed efficiency, morbidity and mortality, as addition group 2;
The above-mentioned large yellow croaker for the fish feed additive rich in γ-aminobutyric acid for being not added with embodiment 1-6 is taken to support simultaneously Grow feed, continuously feed large yellow croaker (500) 8 weeks, and gather acquisition cortisol, serum glucose, rate of body weight gain, feed efficiency, Morbidity and mortality;As a control group 2.
Cortisol, serum glucose, rate of body weight gain, feed efficiency, the incidence of disease and the death of above-mentioned addition group 2 and control group 2 The result of rate see the table below 3.
Table 3
It can be seen from table 2 and table 3, with the feeding of the fish feed additive rich in γ-aminobutyric acid added with the present invention Material feeds crucian and large yellow croaker, cortisol, serum glucose, the morbidity and mortality of crucian are below being not added with above-mentioned feed The fish of the control group of additive, the daily ingestion amount of crucian and average daily gain are above being not added with pair of above-mentioned feed addictive According to the fish of group;Cortisol, serum glucose, the morbidity and mortality of large yellow croaker are below being not added with above-mentioned feed addictive Control group fish, the rate of body weight gain and feed efficiency of large yellow croaker are above being not added with the fish of the control group of above-mentioned feed addictive Class.
In summary, the fish feed additive provided by the invention rich in γ-aminobutyric acid is highly dense with effectively alleviating Shoal of fish stress reaction is spent, improves fish feed intake, improves daily gain, reduces antibiotic usage amount, reduces disease incident and dead The advantages of dying rate.
Embodiments of the invention are the foregoing is only, are not intended to limit the scope of the invention, it is every to utilize this hair The equivalents that bright description is made, or the technical field of correlation is directly or indirectly used in, similarly it is included in this hair In bright scope of patent protection.

Claims (7)

1. a kind of fish feed additive rich in γ-aminobutyric acid, it is characterised in that including following raw material:γ-ammonia Base butyric acid 20-30 parts, superoxide dismutase 5-8 parts, Lavender 1-5 parts, grape-kernel oil 1-5 parts, chamomile essential oil 2-4 Part, vitamin C 5-10 parts, radix pseudostellariae 5-10 parts, vitamin E 3-5 parts, folic acid 2-5 parts, antibacterial peptide 8-12 parts, starch 18-22 parts With hydroxypropyl methyl cellulose 6-10 parts.
2. the fish feed additive according to claim 1 rich in γ-aminobutyric acid, it is characterised in that the starch For 20 parts.
3. the fish feed additive according to claim 1 rich in γ-aminobutyric acid, it is characterised in that the hydroxypropyl Ylmethyl cellulose is 8 parts.
4. a kind of fish feed rich in γ-aminobutyric acid, it is characterised in that including described in claim 1-3 any one Fish feed additive.
5. the fish feed according to claim 4 rich in γ-aminobutyric acid, it is characterised in that the fish feed adds Add the addition of agent for the 0.5-2 ‰ of the gross weight of fish feed.
6. a kind of preparation method of the fish feed additive rich in γ-aminobutyric acid, it is characterised in that by claim 1-3 Each raw material ratio by weight of fish feed additive described in any one is mixed, then former in mixed mixing Water is added in material until submerging mixed material, then be granulated and air-dried successively, obtains the fish feed additive.
7. the preparation method of the fish feed additive according to claim 6 rich in γ-aminobutyric acid, its feature exist In first radix pseudostellariae being crushed, then carry out above-mentioned married operation.
CN201711037392.9A 2017-10-30 2017-10-30 Fish feed, feed addictive and preparation method thereof Pending CN107594227A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108402304A (en) * 2018-04-13 2018-08-17 宁德师范学院 A kind of Larimichthys crocea feed addictive and the preparation method and application thereof
CN111443744A (en) * 2020-04-17 2020-07-24 浙江大学 Recirculating aquaculture variable-speed flow intelligent control system based on fish shoal behavior and ammonia discharge law feedback

Citations (2)

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Publication number Priority date Publication date Assignee Title
CN102125168A (en) * 2010-01-12 2011-07-20 杭州康德权饲料有限公司 Preparation method of gamma-aminobutyric acid coated when passing rumen
CN103125777A (en) * 2013-03-21 2013-06-05 曾龙 Pomfret anti-stress health care agent

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125168A (en) * 2010-01-12 2011-07-20 杭州康德权饲料有限公司 Preparation method of gamma-aminobutyric acid coated when passing rumen
CN103125777A (en) * 2013-03-21 2013-06-05 曾龙 Pomfret anti-stress health care agent

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* Cited by examiner, † Cited by third party
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108402304A (en) * 2018-04-13 2018-08-17 宁德师范学院 A kind of Larimichthys crocea feed addictive and the preparation method and application thereof
CN108402304B (en) * 2018-04-13 2021-06-29 宁德师范学院 Feed additive for large yellow croaker and preparation method and application thereof
CN111443744A (en) * 2020-04-17 2020-07-24 浙江大学 Recirculating aquaculture variable-speed flow intelligent control system based on fish shoal behavior and ammonia discharge law feedback
CN111443744B (en) * 2020-04-17 2021-03-09 浙江大学 Recirculating aquaculture variable-speed flow intelligent control system based on fish shoal behavior and ammonia discharge law feedback

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