CN107583005A - A kind of formula and its extraction process for invigorating the spleen middle benefit gas - Google Patents

A kind of formula and its extraction process for invigorating the spleen middle benefit gas Download PDF

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Publication number
CN107583005A
CN107583005A CN201710405017.9A CN201710405017A CN107583005A CN 107583005 A CN107583005 A CN 107583005A CN 201710405017 A CN201710405017 A CN 201710405017A CN 107583005 A CN107583005 A CN 107583005A
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CN
China
Prior art keywords
invigorating
benefit gas
middle benefit
spleen
time
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Pending
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CN201710405017.9A
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Chinese (zh)
Inventor
刘海涛
叶立仁
钱怀玉
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HEFEI YUANZHI PHARMACEUTICAL R & D Co Ltd
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HEFEI YUANZHI PHARMACEUTICAL R & D Co Ltd
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Priority to CN201710405017.9A priority Critical patent/CN107583005A/en
Publication of CN107583005A publication Critical patent/CN107583005A/en
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Abstract

A kind of formula and its extraction process for invigorating the spleen middle benefit gas.HERBA EPIMEDII, Chinese cassia tree, cassia twig, dried orange peel, Buddha's hand, Fructus Aurantii, the banksia rose, rhizoma zingiberis, pyrola, Rhizoma Atractylodis Macrocephalae preparata, the taste medicinal material of Radix Codonopsis 11 add water to cook 3 times, each plus 10 times of amount water, 1.5 hours every time, collecting decoction, filtration, filtrate are concentrated into relative density 1.38~1.40, add ethanol precipitation 2 times, first time alcohol content is 70%, and second of alcohol content is 80%, stand 12 hours every time, filtration, filtrate recycling ethanol, obtains concentrate, dry, gained medicinal powder is main ingredient raw material.The present invention is extracted and purifying process to prescription Chinese medicine, after the effective substance mixing of acquisition, as the main ingredient raw material of invigorating the spleen middle benefit gas side, is laid the foundation to prepare the related formulation of invigorating the spleen middle benefit gas curative for effect, safely controllable, that dose is small to biddability is good.

Description

A kind of formula and its extraction process for invigorating the spleen middle benefit gas
Technical field
The present invention relates to the field of Chinese medicines, specifically, is related to a kind of formula and its extraction process for invigorating the spleen middle benefit gas.
Background technology
Invigorating the spleen middle benefit gas side demonstrate,proves as preparation in the institute of institute of traditional Chinese medicine of Tianzhang City, clinically prolonged application in YANG deficiency of the spleen and stomach, obtains Good result.The party why wrout iron director's traditional Chinese physician's clinical experience agreement side, be initially clinical decoction side, HERBA EPIMEDII, Chinese cassia tree are Main ingredient, ERXIAN TANG, xiangsha liujun pill, lizhong decoction conjunction sideization is taken to cut out, curative effect is obvious, for the swollen of main sick main symptom, pain, tells, rushes down, cold Deng, be followed by fixed as pill Clinical practice, curative effect reaches more than 90% (healing improvement rate), in initial stage side using regulating qi-flowing for strengthening spleen as It is main, the medicine of invigorating the spleen middle benefit gas is adjusted in later stage side, its card curative effect to deficiency-cold in spleen and stomach is more prominent, adds clinical efficacy.
YANG deficiency of the spleen and stomach card is one of clinical common frdquently encountered disease card, and clinical manifestation is that gastral cavilty hinders swollen, stomachache belch, chilly limb The main pathogenesis of the disease such as cold, get Wen Zeshu, diarrhea etc., " epigastric pain " " abdominal distension " " vomiting ", " diarrhea " " feeling of fullness disease " is: Ferritic is weakness of the spleen and the stomach, insufficiency of spleen-YNAG, eating cold and uncooked food excessively, touches and emits chill, injure spleen sun, cross and cause hypoactivity of spleen-YANG with cold and cool gram of agent cut down, There is gasteremphraxis and hinder in deficiency-cold in middle-JIAO, the dysfunction of the spleen in transport, disturbance in ascending and descending, have a stomachache indistinctly, the happiness of happiness temperature by, it is tired to the cold aggravate, god it is tired Power, diarrhea, aversion to cold and cold limbs, vomiting receive it is few wait disease.There is warmly invigorating spleen and stomach, eliminating cold to stop pain, regulating functional activities of qi, invigorating the spleen to help for full side Transport, the ruffian that disappears appetizing the effect of.
At present, above-mentioned illness market primary treatment medicine has motivator medicine, antiacid acid-suppressing medicine, mucosa protective agent etc., more For symptomatic treatment, long-term efficacy is not good enough, and long-term use of security is indefinite, expensive, and especially aversion to cold and cold limbs is lacked Special curative effect, in order to adapt to clinical requirement, preferably release sufferer sufferings, the present invention using treat YANG deficiency of the spleen and stomach card patient as pair As developing and developing i.e. safety and for the purpose of effective Chinese medicine preparation.
The content of the invention
Inventive formulation with HERBA EPIMEDII, Chinese cassia tree, cassia twig, dried orange peel, Buddha's hand, Fructus Aurantii, the banksia rose, rhizoma zingiberis, pyrola, Rhizoma Atractylodis Macrocephalae preparata, The taste medicinal material of Radix Codonopsis 11 forms invigorating the spleen middle benefit gas side according to a certain percentage, and prescription Chinese medicine is carried out by using water extract-alcohol precipitation method Extraction and purifying process, after the effective substance mixing of acquisition, as the main ingredient raw material of invigorating the spleen middle benefit gas side, for prepare it is curative for effect, The related formulation of the invigorating the spleen middle benefit gas safely controllable, dose is small to biddability is good lays the foundation.
In order to solve the above-mentioned technical problem, the invention provides following technical scheme:A kind of matching somebody with somebody for invigorating the spleen middle benefit gas Side, including HERBA EPIMEDII 10-20g, Chinese cassia tree 3-6g, cassia twig 8-12g, dried orange peel 8-12g, Buddha's hand 9-13g, Fructus Aurantii 7-15g, banksia rose 2- 5g, rhizoma zingiberis 1-4g, pyrola 9-13g, Rhizoma Atractylodis Macrocephalae preparata 8-12g, Radix Codonopsis 10-20g.
Present invention also offers a kind of formula extraction process for invigorating the spleen middle benefit gas, its step are as follows:
HERBA EPIMEDII, Chinese cassia tree, cassia twig, dried orange peel, Buddha's hand, Fructus Aurantii, the banksia rose, rhizoma zingiberis, pyrola, Rhizoma Atractylodis Macrocephalae preparata, the taste medicinal material of Radix Codonopsis 11 Add water to cook 3 times, every time plus 10 times amount water, 1.5 hours every time, collecting decoction, filtration, filtrate be concentrated into relative density 1.38~ 1.40, add ethanol precipitation 2 times, first time alcohol content is 70%, and second of alcohol content is 80%, stands 12 hours every time, filtration, Filtrate recycling ethanol, concentrate is obtained, dried, gained medicinal powder is main ingredient raw material;
Content after extraction purification, addition dextrin is appropriate, and equivalent is progressively increased after method mixing, with 70% ethanol softwood, system Grain, 60 DEG C of dryings, whole grain, produces invigorating the spleen middle benefit gas granule.
The present invention has invigorating the spleen middle benefit gas effect, to reach treatment deficiency of spleen and stomach Yang type gastritis, peptic ulcer, functional digestive The resistance of gastral cavilty caused by bad, chronic enteritis etc. is swollen, the purpose of have a stomachache belch, aversion to cold and cold limbs, get Wen Zeshu, diarrhea etc., is controlled Disease relates generally to YANG deficiency of the spleen and stomach card.
Embodiment
Embodiment 1
Weigh HERBA EPIMEDII 100g, Chinese cassia tree 40g, cassia twig 100g, pyrola 100g, Rhizoma Atractylodis Macrocephalae preparata 100g, Radix Codonopsis 150g, dried orange peel 100g, Buddha's hand 100g, stir-baked FRUCTUS AURANTII in bran 100g, banksia rose 30g, rhizoma zingiberis 30g,
Dextrin, appropriate amount of ethanol.
Extraction process is shown as to HERBA EPIMEDII, Chinese cassia tree, cassia twig, dried orange peel, Buddha's hand, Fructus Aurantii, the banksia rose, rhizoma zingiberis, pyrola, Jiao Bai Art, Radix Codonopsis are extracted and purified, and particular content is mainly as follows:HERBA EPIMEDII, Chinese cassia tree, cassia twig, dried orange peel, Buddha's hand, Fructus Aurantii, the banksia rose, Rhizoma zingiberis, pyrola, Rhizoma Atractylodis Macrocephalae preparata, the taste medicinal material of Radix Codonopsis 11 are added water to cook 3 times, and every time plus 10 times are measured water, 1.5 hours every time, are merged and are decocted Liquid, filtration, filtrate are concentrated into (70 DEG C) Zuo You of relative density 1.38~1.40, add ethanol precipitation 2 times, and first time alcohol content is 70%, second of alcohol content is 80%, stands 12 hours every time, filtration, filtrate recycling ethanol, obtains concentrate, is dried, gained medicine Powder is main ingredient raw material.
HERBA EPIMEDII, Chinese cassia tree, cassia twig, dried orange peel, Buddha's hand, Fructus Aurantii, the banksia rose, rhizoma zingiberis, pyrola, Rhizoma Atractylodis Macrocephalae preparata, Radix Codonopsis are extracted, is merged Content after extraction purification, addition dextrin is appropriate, and equivalent is progressively increased after method mixing, and with 70% ethanol softwood, granulation, 60 DEG C dry It is dry, whole grain, produce invigorating the spleen middle benefit gas granule.

Claims (2)

  1. A kind of 1. formula for invigorating the spleen middle benefit gas, it is characterised in that including HERBA EPIMEDII 10-20g, Chinese cassia tree 3-6g, cassia twig 8-12g, Dried orange peel 8-12g, Buddha's hand 9-13g, Fructus Aurantii 7-15g, banksia rose 2-5g, rhizoma zingiberis 1-4g, pyrola 9-13g, Rhizoma Atractylodis Macrocephalae preparata 8-12g, Radix Codonopsis 10-20g。
  2. 2. a kind of formula extraction process for invigorating the spleen middle benefit gas, it is characterised in that its step is as follows:
    HERBA EPIMEDII, Chinese cassia tree, cassia twig, dried orange peel, Buddha's hand, Fructus Aurantii, the banksia rose, rhizoma zingiberis, pyrola, Rhizoma Atractylodis Macrocephalae preparata, the taste medicinal material of Radix Codonopsis 11 add water Decoct 3 times, every time plus 10 times amount water, 1.5 hours every time, collecting decoction, filtration, filtrate be concentrated into relative density 1.38~ 1.40, add ethanol precipitation 2 times, first time alcohol content is 70%, and second of alcohol content is 80%, stands 12 hours every time, filtration, Filtrate recycling ethanol, concentrate is obtained, dried, gained medicinal powder is main ingredient raw material;
    Content after extraction purification, addition dextrin is appropriate, and equivalent is progressively increased after method mixing, with 70% ethanol softwood, pelletizes, and 60 DEG C drying, whole grain, produces invigorating the spleen middle benefit gas granule.
CN201710405017.9A 2017-06-01 2017-06-01 A kind of formula and its extraction process for invigorating the spleen middle benefit gas Pending CN107583005A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2097058C1 (en) * 1996-07-17 1997-11-27 Малышев Валерий Павлович Method of treatment of gastroenteric illnesses
CN102512642A (en) * 2011-12-15 2012-06-27 天长市中医院 Medicinal composition for treating spleen and stomach diseases and application thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2097058C1 (en) * 1996-07-17 1997-11-27 Малышев Валерий Павлович Method of treatment of gastroenteric illnesses
CN102512642A (en) * 2011-12-15 2012-06-27 天长市中医院 Medicinal composition for treating spleen and stomach diseases and application thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
孟彪等: "《杏林传薪 赵和平临床经验与学术思想研究》", 31 March 2015, 人民军医出版社 *
朱晓薇等: "《中药药剂学》", 31 May 2015, 中国农业大学出版社 *
鲁耀邦等: "《中药学》", 31 December 2015, 中国农业大学出版社 *

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