CN107582720A - A kind of Chinese medicine composition for treating arthralgia pain due to rheumatism and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating arthralgia pain due to rheumatism and preparation method thereof Download PDFInfo
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Abstract
The present invention provides a kind of Chinese medicine composition for treating arthralgia pain due to rheumatism and preparation method thereof.The Chinese medicine composition for the treatment of arthralgia pain due to rheumatism provided by the invention, altogether for monarch drug in a prescription, common compatibility, is played wind-damp dispelling, filling liver kidney, the effect of strengthening the bones and muscles, removes wind clearing damp, enjoy excellent health, then numbness pain must be removed altogether with Ramulus Taxilli, the root of bidentate achyranthes, the rhizome of davallia, ramulus mori and pawpaw；Using Radix Angelicae Sinensis, reticulate millettia, the red sage root, ground bettle, teasel root, frankincense and myrrh as ministerial drug, ministerial drug compatibility, take into account blood-nourishing, promoting blood circulation, adjust blood, dredging collateral, joint is supplemented nutrition sliding sharp；Using cassia twig, Chinese cassia tree, saline cistanche, the fleece-flower root and the Radix Astragali as adjutant, common compatibility, QI invigorating Wen Yang is played altogether, warm cold dispelling is wet, the effect of adjusting and reinforcing liver and kidney；Residual drug makes for assistant；The effect of monarch, all medicine compatibilities, plays dispelling wind and eliminating dampness altogether, clearing and activating the channels and collaterals, promoting blood circulation and removing blood stasis, and warm cold dispelling is coagulated, reach the purpose for the treatment of arthralgia pain due to rheumatism disease.
Description
Technical field
The invention belongs to tcm field, and in particular to a kind of Chinese medicine composition for treating arthralgia pain due to rheumatism and its preparation side
Method.
Background technology
Arthralgia pain due to rheumatism be caused by the damp evil that is affected by the cold with limbs joint pain, it is miserable, numb, weigh, and activity
Disease based on obstacle.The wet heresy invasion and attack limbs channels and collaterals of chill, cause QI-blood circulation not smooth, blockage of channel, not general rule pain.In addition
After channels and collaterals stasis blocking, joint, which is lost, supports, not Rong Ze pains.The main symptom of arthralgia pain due to rheumatism is arthralgia, morning stiffness, arthroncus and pressure
Bitterly, painful swelling of joints and joint deformity and dysfunction.Human synovial crymodynia often betides catch a cold and catch cold after, as the age increases
It is big to occur more, to be health problem common in life.Chemical antalgica has Diclofenac, celecoxib, brufen, salicylic acid
Methyl esters etc., Chinese medicine have various brands Chinese medicine patch such as Yunnan Baiyao etc..It is oral medicine that chemicals is most of, a small amount of local topical production
Product have dosage limitation, and can not be long-term use of, there is certain liver renal toxicity.Existing Chinese patent drug patch liquid medicine taste is dense, makes
After unsightly, activity is inconvenient after joint part use, feels inconvenient after use.
The content of the invention
In order to solve the above technical problems, the present invention provides one kind using Chinese patent drug material as raw material, given birth to by specific technique
Produce obtain have no toxic side effect, can pain caused by rapid recovery arthralgia pain due to rheumatism, smell it is pure and fresh treatment arthralgia pain due to rheumatism in
Drug composition and preparation method thereof.
It is an object of the invention to provide a kind of Chinese medicine composition for treating arthralgia pain due to rheumatism.
It is a further object of the present invention to provide a kind of preparation method for the Chinese medicine composition for treating arthralgia pain due to rheumatism.
Arthralgia pain due to rheumatism be caused by the damp evil that is affected by the cold with limbs joint pain, it is miserable, numb, weigh, and activity
Disease based on obstacle.The wet heresy invasion and attack limbs channels and collaterals of chill, cause QI-blood circulation not smooth, blockage of channel, not general rule pain.In addition
After channels and collaterals stasis blocking, joint, which is lost, supports, not Rong Ze pains.According to this nosogenesis.R. concomitans wind-dispelling of the present invention, dehumidifying, dredging collateral,
The methods such as cold dispelling, Wen Yang, QI invigorating, blood-nourishing, heat-clearing are taken into account, therefore arthralgia pain due to rheumatism can be treated.The through disease of the efficacy of a drug is made using external therapy
Stove, local action.Specifically：
The Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, the Chinese medicine composition bag
Include the raw material of following parts by weight：Pseudo-ginseng 5-8 parts, tortoise plastron 5-7 parts, root of bidentate achyranthes 5-7 parts, safflower 3-7 parts, seed of cowherb 1-3 parts, cultivated land
Yellow 1-4 parts, reticulate millettia 4-7 parts, rhizome of davallia 2-5 parts, red sage root 5-7 parts, scythian lamb rhizome 1-4 parts, lopseed 1-3 parts, ramulus mori 1-2
Part, shametace 1-4 parts, wintergreen 1-3 parts, cassia twig 1-3 parts, leech 3-5 parts, lycopodium calvatum 1-4 parts, Semen Cuscutae 1-3 parts, meat
Desert cistanche 1-5 parts, myrrh 1-3 parts, Chinese cassia tree 1-4 parts, fleece-flower root 2-5 parts, radix paeoniae rubrathe 3-5 parts, teasel root 2-4 parts, radix glycyrrhizae 3-7 parts, the root of three-nerved spicebush
2-4 parts, ground bettle 3-5 parts, frankincense 2-4 parts, Ramulus Taxilli 3-5 parts, Radix Astragali 1-4 parts, pawpaw 2-4 parts and Radix Angelicae Sinensis 2-3 parts.
The Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, it is preferable that the Chinese medicine
Composition includes the raw material of following parts by weight：Pseudo-ginseng 5-8 parts, tortoise plastron 5-7 parts, root of bidentate achyranthes 5-7 parts, safflower 3-7 parts, seed of cowherb 1-
3 parts, prepared rhizome of rehmannia 1-4 parts, reticulate millettia 4-7 parts, rhizome of davallia 2-5 parts, red sage root 5-7 parts, scythian lamb rhizome 1-4 parts, lopseed 1-3 parts,
Ramulus mori 1-2 parts, shametace 1-4 parts, wintergreen 1-3 parts, cassia twig 1-3 parts, leech 3-5 parts, lycopodium calvatum 1-4 parts, Semen Cuscutae
1-3 parts, saline cistanche 1-5 parts, myrrh 1-3 parts, Chinese cassia tree 1-4 parts, fleece-flower root 2-5 parts, radix paeoniae rubrathe 3-5 parts, teasel root 2-4 parts, radix glycyrrhizae 3-7
Part, root of three-nerved spicebush 2-4 parts, ground bettle 3-5 parts, frankincense 2-4 parts, Ramulus Taxilli 3-5 parts, Radix Astragali 1-4 parts, pawpaw 2-4 parts, Radix Angelicae Sinensis 2-3 parts,
Pig label grass 2-5 parts, rheum officinale 1-2 parts, iron wire lotus leaf 2-4 parts, bark of eucommia 3-5 parts, anise seed 1-3 parts, fruit of summer cypress 1-3 parts, barrenwort
1-3 parts, root bark of shaggy-fruited dittany 1-3 parts, cortex acanthopanacis 2-3 parts, corydalis tuber 1-3 parts, oldenlandia diffusa 1-2 parts, banksia rose 2-4 parts and ginseng 2-4
Part.
The Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, it is preferable that the Chinese medicine
Composition includes the raw material of following parts by weight：6 parts of pseudo-ginseng, 6 parts of tortoise plastron, 6 parts of the root of bidentate achyranthes, 5 parts of safflower, 2 parts of the seed of cowherb, prepared rhizome of rehmannia
3 parts, 5 parts of reticulate millettia, 4 parts of the rhizome of davallia, 6 parts of the red sage root, 3 parts of scythian lamb rhizome, 2 parts of lopseed, 1.5 parts of ramulus mori, shametace 3
Part, 2 parts of wintergreen, 2 parts of cassia twig, 4 parts of leech, 3 parts of lycopodium calvatum, 2 parts of Semen Cuscutae, 3 parts of saline cistanche, 2 parts of myrrh, 2.5 parts of Chinese cassia tree,
4 parts of the fleece-flower root, 4 parts of the radix paeoniae rubrathe, 3 parts of teasel root, 5 parts of radix glycyrrhizae, 3 parts of the root of three-nerved spicebush, 4 parts of ground bettle, 3 parts of frankincense, 4 parts of Ramulus Taxilli, the Radix Astragali 3
Part, 3 parts of pawpaw, 2.5 parts of Radix Angelicae Sinensis, 4 parts of pig label grass, 1.5 parts of rheum officinale, 3 parts of iron wire lotus leaf, 4 parts of the bark of eucommia, 2 parts of anise seed, the fruit of summer cypress
2 parts, 2 parts of barrenwort, 2 parts of the root bark of shaggy-fruited dittany, 2.5 parts of cortex acanthopanacis, 2 parts of corydalis tuber, 1.5 parts of oldenlandia diffusa, 3 parts of the banksia rose and ginseng 3
Part.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, the side
Method comprises the following steps：
(1) pseudo-ginseng is taken, dry, pulverize, sieves, obtains Radix Notoginseng powder；Ginseng dry, pulverize, sieve, obtain ginseng pulverate；
Radix rehmanniae recen is taken, yellow rice wine wine system, dry, pulverize, obtains wine cultivated land bloom；
(2) remaining raw material is crushed, sieves, mixed powder is obtained, then by the Radix Notoginseng powder obtained in step (1), ginseng
Powder and wine cultivated land bloom are well mixed with the mixed powder, add the alcohol of 4.5-6 times of weight, are soaked 21-30 days, are obtained wine
Soak Chinese medicine composition；
(3) the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 40-60min, is heated to 60-80
DEG C, cool down, filtering, take filtrate, obtain the Chinese medicine composition of the treatment arthralgia pain due to rheumatism.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, preferably
Ground, in step (1), pseudo-ginseng is taken, it is less than 10% to be dried at 45-50 DEG C to the moisture in pseudo-ginseng.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, preferably
Ground, in step (1), the particle diameter of the Radix Notoginseng powder is 900-1300 mesh, and the particle diameter of the ginseng pulverate is 800-1200 mesh.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, preferably
Ground, in step (1), the preparation method of the wine cultivated land bloom is：Radix rehmanniae recen is taken, is cut into slices, adds yellow rice wine, the yellow rice wine and institute
The weight ratio for stating radix rehmanniae recen is 0.8-1:1,20-30h is stood, treats that yellow rice wine is absorbed by glutinous rehmannia completely, is put into sealing device,
80-100 DEG C of boiling 45-60h, it is dry 3-5 days at 40-45 DEG C, 100-200 mesh is crushed to, obtains wine cultivated land bloom.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, preferably
Ground, in step (2), the particle diameter of the mixed powder is 60-200 mesh.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, preferably
Ground, in step (2), the volume fraction of the alcohol is 75-95%.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, preferably
Ground, in step (3), the heating rate of the heating is 2-3 DEG C/min.
The preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to the specific embodiment of the invention, preferably
Ground, in step (3), the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 40-60min, is heated to 60-
80 DEG C, it is incubated 2-3h.
The Chinese medicine composition for the treatment of arthralgia pain due to rheumatism provided by the invention can add excipient and be prepared into suitable Clinical practice
Formulation, such as emulsion, aqua, patch agent, tincture, spraying.
Beneficial effects of the present invention are：
The present invention provides a kind of Chinese medicine composition for treating arthralgia pain due to rheumatism and preparation method thereof.Treatment wind provided by the invention
The Chinese medicine composition of arthritis with fixed pain caused by dampness pain, altogether for monarch drug in a prescription, common compatibility, plays wind-dispelling altogether with Ramulus Taxilli, the root of bidentate achyranthes, the rhizome of davallia, ramulus mori and pawpaw
Wet, filling liver kidney, the effect of strengthening the bones and muscles, remove wind clearing damp, enjoy excellent health, then numbness pain must be removed；With Radix Angelicae Sinensis, reticulate millettia, the red sage root, ground beetle
Worm, teasel root, frankincense and myrrh are ministerial drug, ministerial drug compatibility, take into account blood-nourishing, promoting blood circulation, adjust blood, dredging collateral, joint is supplemented nutrition sliding sharp；
Using cassia twig, Chinese cassia tree, saline cistanche, the fleece-flower root and the Radix Astragali as adjutant, common compatibility, QI invigorating Wen Yang is played altogether, warm cold dispelling is wet, adjusting and reinforcing liver and kidney
The effect of；Residual drug makes for assistant；Person who has rendered outstanding service's assistant makes, all medicine compatibilities, plays clearing and activating the channels and collaterals, promoting blood circulation and removing blood stasis, dehumidifying, the work(of cold dispelling altogether
Effect, reach the purpose for the treatment of arthralgia pain due to rheumatism disease.
Ramulus Taxilli, wind-damp dispelling, liver and kidney benefiting, strengthening the bones and muscles, control rheumatism disadvantage pain, soreness of waist and knee joint；The root of bidentate achyranthes, invigorate blood circulation, liver and kidney benefiting,
Strengthening the bones and muscles, stagnation resolvation Li Shui, traumatic injury, soreness of waist and knee joint are controlled, bitter is good at drop-down, and can ensuring proper downward flow of the blood, and guides drugs to illness station the efficacy of a drug；
The rhizome of davallia, promoting circulation of blood arteries and veins, continuous muscles and bones, analgesic of curing the wound, control damage muscles and bones, pain caused by ecchymoma；Ramulus mori, wind-damp dispelling, degrading the channel, sharp joint,
Control rheumatism disadvantage pain, spasm of limbs；Pawpaw, relaxing tendons and activating collaterals, control rheumatism spasm of muscles and vessels；Five medicine phases close, play altogether wind-damp dispelling, filling liver kidney,
The effect of strengthening the bones and muscles is monarch drug in a prescription, removes wind clearing damp, enjoys excellent health, then numbness pain must be removed.
Radix Angelicae Sinensis, blood circulation promoting and enriching, eliminating cold to stop pain, control stasis and tremble with fear and coagulate, wind-damp numbness pain；Pseudo-ginseng, hemostasis promoting blood circulation, eliminating stasis to subdue swelling
Analgesic, control the damage stagnant pain of the stasis of blood；Reticulate millettia, promoting circulation of blood dissipates the stasis of blood, relaxing tendons and activating collaterals, and can relieve pain；The red sage root, activating blood removing stasis, promoting blood circulation for regulating menstruation,
Cool blood to disappear carbuncle, control blood stasis rheumatism disadvantage pain；Ground bettle, taste it is salty enter blood, property is apt to walk to alter, activating blood circulation and reducing swelling, relieves pain by silt；Teasel root, synthetism,
Control traumatic injury, injury of tendon and muscle fracture, pain caused by ecchymoma；Frankincense, detumescence and promoting granulation, control traumatic injury；Myrrh, promoting blood circulation to remove blood stasis analgesic, blood
Gas profit, detumescence and promoting granulation；Above seven flavor medicine thing, take into account blood-nourishing, promoting blood circulation, adjust blood, dredging collateral, joint is supplemented nutrition sliding sharp, be altogether minister
Medicine.
Cassia twig, sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi, activate yang cold dispelling；Chinese cassia tree, pungent sweet big heat, cold dispelling power is male, Wen Li
It is supporing yang, warming and activating meridian, treat arthritis pain in the back；Saline cistanche, it is sexy sweet, it is salty and gentle not dry, kidney deficiency and liver is controlled, waist kidney is aching and limp,
Muscles and bones is powerless；The fleece-flower root, it is warm but not dry, control deficiency of kidney-essence, soreness and weakness of waist and knees；The Radix Astragali, tonifying Qi and lifting yang, inducing diuresis for removing edema, myogenic, Li Shui
Wet edema；Five tastes medicine QI invigorating Wen Yang, warm cold dispelling is wet, adjusting and reinforcing liver and kidney, is adjutant.
Tortoise plastron, replenishing kidney and strengthening bone；Rheum officinale, invigorate blood circulation；Leech, dissipating blood stasis with potent drugs Xiao Disorder, controls blood stagnancy due to deficiency of QI, hemiplegia, limb
Body activity is unfavorable；Corydalis tuber, promoting blood circulation, promoting qi circulation and relieving pain, controls stagnation of QI-blood pain；Lopseed, wind-damp dispelling, Soothe tendons and activating-blood anodyne, muscle
Bone contracture；Residual drug makes for assistant, with monarch drug in a prescription, ministerial drug, the common compatibility of adjutant, reaches clearing and activating the channels and collaterals jointly, promotes QI-blood circulation,
The effect of eliminating arthralgia pain due to rheumatism.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below
Detailed description.Obviously, described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are resulting on the premise of creative work is not made to be owned
Other embodiment, belong to the scope that the present invention is protected.
Embodiment 1
The Chinese medicine composition of arthralgia pain due to rheumatism is treated, the Chinese medicine composition includes the raw material of following weight：Pseudo-ginseng 50g, tortoise
First 50g, root of bidentate achyranthes 50g, safflower 30g, seed of cowherb 10g, prepared rhizome of rehmannia 10g, reticulate millettia 40g, rhizome of davallia 20g, red sage root 50g, golden hair
Rhizoma cibotii 10g, lopseed 10g, ramulus mori 10g, shametace 10g, wintergreen 10g, cassia twig 10g, leech 30g, lycopodium calvatum 10g,
Semen Cuscutae 10g, saline cistanche 10g, myrrh 10g, Chinese cassia tree 10g, fleece-flower root 20g, radix paeoniae rubrathe 30g, teasel root 20g, radix glycyrrhizae 30g, the root of three-nerved spicebush
20g, ground bettle 30g, frankincense 20g, Ramulus Taxilli 30g, Radix Astragali 10g, pawpaw 20g and Radix Angelicae Sinensis 20g.
The preparation method of the Chinese medicine composition of above-mentioned treatment arthralgia pain due to rheumatism, the described method comprises the following steps：
(1) pseudo-ginseng is taken, it is 8% to be dried at 50 DEG C to the moisture in pseudo-ginseng, crushes, crosses 1300 mesh sieves, obtain pseudo-ginseng
Powder；Radix rehmanniae recen is taken, is cut into slices, adds yellow rice wine, the weight ratio of the yellow rice wine and the radix rehmanniae recen is 1:1,30h is stood, treats that yellow rice wine is complete
Absorbed, be put into sealing device by glutinous rehmannia entirely, in 100 DEG C of boiling 60h, dried 5 days at 45 DEG C, be crushed to 200 mesh, obtain wine system
Cultivated land bloom；
(2) remaining raw material is crushed, sieves, obtain mixed powder, the particle diameter of the mixed powder is 200 mesh, then will step
Suddenly the Radix Notoginseng powder and wine cultivated land bloom obtained in (1) is well mixed with the mixed powder, is added 6 times of bulking value fractions and is
95% alcohol, soak 30 days, obtain immersed-in-wine Chinese medicine composition；
(3) the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 60min, with 3 DEG C/min heating
Speed is heated to 80 DEG C, is incubated 3h, cools down, and filtering, takes filtrate, obtains the Chinese medicine composition of the treatment arthralgia pain due to rheumatism.
Embodiment 2
The Chinese medicine composition of arthralgia pain due to rheumatism is treated, the Chinese medicine composition includes the raw material of following weight：Pseudo-ginseng 80g, tortoise
First 70g, root of bidentate achyranthes 70g, safflower 70g, seed of cowherb 30g, prepared rhizome of rehmannia 40g, reticulate millettia 70g, rhizome of davallia 50g, red sage root 70g, golden hair
Rhizoma cibotii 40g, lopseed 30g, ramulus mori 20g, shametace 40g, wintergreen 30g, cassia twig 30g, leech 50g, lycopodium calvatum 40g,
Semen Cuscutae 30g, saline cistanche 50g, myrrh 30g, Chinese cassia tree 40g, fleece-flower root 50g, radix paeoniae rubrathe 50g, teasel root 40g, radix glycyrrhizae 70g, the root of three-nerved spicebush
40g, ground bettle 50g, frankincense 40g, Ramulus Taxilli 50g, Radix Astragali 40g, pawpaw 40g and Radix Angelicae Sinensis 30g.
The preparation method of the Chinese medicine composition of above-mentioned treatment arthralgia pain due to rheumatism, the described method comprises the following steps：
(1) pseudo-ginseng is taken, it is 8% to be dried at 50 DEG C to the moisture in pseudo-ginseng, crushes, crosses 1300 mesh sieves, obtain pseudo-ginseng
Powder；Radix rehmanniae recen is taken, is cut into slices, adds yellow rice wine, the weight ratio of the yellow rice wine and the radix rehmanniae recen is 1:1,30h is stood, treats that yellow rice wine is complete
Absorbed, be put into sealing device by glutinous rehmannia entirely, in 100 DEG C of boiling 60h, dried 5 days at 45 DEG C, be crushed to 200 mesh, obtain wine system
Cultivated land bloom；
(2) remaining raw material is crushed, sieves, obtain mixed powder, the particle diameter of the mixed powder is 200 mesh, then will step
Suddenly Radix Notoginseng powder, ginseng pulverate and the wine cultivated land bloom obtained in (1) is well mixed with the mixed powder, adds 6 times of bulking values
Fraction is 95% alcohol, soaks 30 days, obtains immersed-in-wine Chinese medicine composition；
(3) the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 60min, with 3 DEG C/min heating
Speed is heated to 80 DEG C, is incubated 3h, cools down, and filtering, takes filtrate, obtains the Chinese medicine composition of the treatment arthralgia pain due to rheumatism.
Embodiment 3
The Chinese medicine composition of arthralgia pain due to rheumatism is treated, the Chinese medicine composition includes the raw material of following weight：Pseudo-ginseng 50g, tortoise
First 50g, root of bidentate achyranthes 50g, safflower 30g, seed of cowherb 10g, prepared rhizome of rehmannia 10g, reticulate millettia 40g, rhizome of davallia 20g, red sage root 50g, golden hair
Rhizoma cibotii 10g, lopseed 10g, ramulus mori 10g, shametace 10g, wintergreen 10g, cassia twig 10g, leech 30g, lycopodium calvatum 10g,
Semen Cuscutae 10g, saline cistanche 10g, myrrh 10g, Chinese cassia tree 10g, fleece-flower root 20g, radix paeoniae rubrathe 30g, teasel root 20g, radix glycyrrhizae 30g, the root of three-nerved spicebush
20g, ground bettle 30g, frankincense 20g, Ramulus Taxilli 30g, Radix Astragali 10g, pawpaw 20g, Radix Angelicae Sinensis 20g , pig label grass 20g, rheum officinale 10g, iron
Line lotus leaf 20g, bark of eucommia 30g, anise seed 10g, fruit of summer cypress 10g, barrenwort 10g, root bark of shaggy-fruited dittany 10g, cortex acanthopanacis 20g, corydalis tuber
10g, oldenlandia diffusa 10g, banksia rose 20g and ginseng 20g.
The preparation method of the Chinese medicine composition of above-mentioned treatment arthralgia pain due to rheumatism, the described method comprises the following steps：
(1) pseudo-ginseng is taken, it is 10% to be dried at 45 DEG C to the moisture in pseudo-ginseng, crushes, crosses 900 mesh sieves, obtain pseudo-ginseng
Powder；Ginseng dry, pulverize, cross 800 mesh sieves, obtain ginseng pulverate；Take radix rehmanniae recen, cut into slices, add yellow rice wine, the yellow rice wine with it is described
The weight ratio of radix rehmanniae recen is 0.8:1,20h is stood, treats that yellow rice wine is absorbed by glutinous rehmannia completely, is put into sealing device, in 80 DEG C of boilings
45h, dried 3 days at 40 DEG C, be crushed to 100 mesh, obtain wine cultivated land bloom；
(2) remaining raw material is crushed, sieves, obtain mixed powder, the particle diameter of the mixed powder is 60 mesh, then by step
(1) Radix Notoginseng powder, ginseng pulverate and the wine cultivated land bloom obtained in is well mixed with the mixed powder, adds 4.5 times of bulking values
Fraction is 75% alcohol, soaks 21 days, obtains immersed-in-wine Chinese medicine composition；
(3) the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 40min, with 2 DEG C/min heating
Speed is heated to 60 DEG C, is incubated 2h, cools down, and filtering, takes filtrate, obtains the Chinese medicine composition of the treatment arthralgia pain due to rheumatism.
Embodiment 4
The Chinese medicine composition of arthralgia pain due to rheumatism is treated, the Chinese medicine composition includes the raw material of following weight：Pseudo-ginseng 80g, tortoise
First 70g, root of bidentate achyranthes 70g, safflower 70g, seed of cowherb 30g, prepared rhizome of rehmannia 40g, reticulate millettia 70g, rhizome of davallia 50g, red sage root 70g, golden hair
Rhizoma cibotii 40g, lopseed 30g, ramulus mori 20g, shametace 40g, wintergreen 30g, cassia twig 30g, leech 50g, lycopodium calvatum 40g,
Semen Cuscutae 30g, saline cistanche 50g, myrrh 30g, Chinese cassia tree 40g, fleece-flower root 50g, radix paeoniae rubrathe 50g, teasel root 40g, radix glycyrrhizae 70g, the root of three-nerved spicebush
40g, ground bettle 50g, frankincense 40g, Ramulus Taxilli 50g, Radix Astragali 40g, pawpaw 40g, Radix Angelicae Sinensis 30g , pig label grass 50g, rheum officinale 20g, iron
Line lotus leaf 40g, bark of eucommia 50g, anise seed 30g, fruit of summer cypress 30g, barrenwort 30g, root bark of shaggy-fruited dittany 30g, cortex acanthopanacis 30g, corydalis tuber
30g, oldenlandia diffusa 20g, banksia rose 40g and ginseng 40g.
The preparation method of the Chinese medicine composition of above-mentioned treatment arthralgia pain due to rheumatism, the described method comprises the following steps：
(1) pseudo-ginseng is taken, it is 8% to be dried at 50 DEG C to the moisture in pseudo-ginseng, crushes, crosses 1300 mesh sieves, obtain pseudo-ginseng
Powder；Ginseng dry, pulverize, cross 1200 mesh sieves, obtain ginseng pulverate；Radix rehmanniae recen is taken, is cut into slices, adds yellow rice wine, the yellow rice wine and institute
The weight ratio for stating radix rehmanniae recen is 1:1,30h is stood, treats that yellow rice wine is absorbed by glutinous rehmannia completely, is put into sealing device, in 100 DEG C of boilings
60h, dried 5 days at 45 DEG C, be crushed to 200 mesh, obtain wine cultivated land bloom；
(2) remaining raw material is crushed, sieves, obtain mixed powder, the particle diameter of the mixed powder is 200 mesh, then will step
Suddenly Radix Notoginseng powder, ginseng pulverate and the wine cultivated land bloom obtained in (1) is well mixed with the mixed powder, adds 6 times of bulking values
Fraction is 95% alcohol, soaks 30 days, obtains immersed-in-wine Chinese medicine composition；
(3) the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 60min, with 3 DEG C/min heating
Speed is heated to 80 DEG C, is incubated 3h, cools down, and filtering, takes filtrate, obtains the Chinese medicine composition of the treatment arthralgia pain due to rheumatism.
Embodiment 5
The Chinese medicine composition of arthralgia pain due to rheumatism is treated, the Chinese medicine composition includes the raw material of following weight：Pseudo-ginseng 60g, tortoise
First 60g, root of bidentate achyranthes 60g, safflower 50g, seed of cowherb 20g, prepared rhizome of rehmannia 30g, reticulate millettia 50g, rhizome of davallia 40g, red sage root 60g, golden hair
Rhizoma cibotii 30g, lopseed 20g, ramulus mori 15g, shametace 30g, wintergreen 20g, cassia twig 20g, leech 40g, lycopodium calvatum 30g,
Semen Cuscutae 20g, saline cistanche 30g, myrrh 20g, Chinese cassia tree 25g, fleece-flower root 40g, radix paeoniae rubrathe 40g, teasel root 30g, radix glycyrrhizae 50g, the root of three-nerved spicebush
30g, ground bettle 40g, frankincense 30g, Ramulus Taxilli 40g, Radix Astragali 30g, pawpaw 30g, Radix Angelicae Sinensis 25g , pig label grass 40g, rheum officinale 15g, iron
Line lotus leaf 30g, bark of eucommia 40g, anise seed 20g, fruit of summer cypress 20g, barrenwort 20g, root bark of shaggy-fruited dittany 20g, cortex acanthopanacis 25g, corydalis tuber
20g, oldenlandia diffusa 15g, banksia rose 30g and ginseng 30g.
The preparation method of the Chinese medicine composition of above-mentioned treatment arthralgia pain due to rheumatism, the described method comprises the following steps：
(1) pseudo-ginseng is taken, it is 8% to be dried at 46 DEG C to the moisture in pseudo-ginseng, crushes, crosses 1200 mesh sieves, obtain pseudo-ginseng
Powder；Ginseng dry, pulverize, cross 1200 mesh sieves, obtain ginseng pulverate；Radix rehmanniae recen is taken, is cut into slices, adds yellow rice wine, the yellow rice wine and institute
The weight ratio for stating radix rehmanniae recen is 1:1,30h is stood, treats that yellow rice wine is absorbed by glutinous rehmannia completely, is put into sealing device, in 100 DEG C of boilings
60h, dried 5 days at 45 DEG C, be crushed to 200 mesh, obtain wine cultivated land bloom；
(2) remaining raw material is crushed, sieves, obtain mixed powder, the particle diameter of the mixed powder is 200 mesh, then will step
Suddenly Radix Notoginseng powder, ginseng pulverate and the wine cultivated land bloom obtained in (1) is well mixed with the mixed powder, adds 6 times of bulking values
Fraction is 75% alcohol, soaks 30 days, obtains immersed-in-wine Chinese medicine composition；
(3) the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 50min, with 2.5 DEG C/min liter
Warm speed is heated to 80 DEG C, is incubated 3h, cools down, and filtering, takes filtrate, obtains the Chinese medicine composition of the treatment arthralgia pain due to rheumatism.
Test example
The arthralgia pain due to rheumatism patient of 49 this products on probation included, the wherein people of male 25, the people of women 24, age minimum 28
It is year, maximum 75 years old；Wherein arthritis and rheumatic arthritis 10；Cervical vertebra ache, dizzy 17, knee joint and leg arthritis
10 bitterly, pain in the back 12.Wherein treated using the present invention.The Chinese medicine group of the treatment arthralgia pain due to rheumatism obtained according to embodiment 5
Compound, affected part is sprayed at, daily 1-2 times, each quantity for spray is 1-2ml, is used continuously 4-6 weeks, observes trier's arthralgia pain due to rheumatism
The improvement situation of related symptoms and sign, is evaluated trial effect by following standard, the results are shown in Table 1.
Morbidity control：After the treatment of 4-6 weeks, the symptom such as pain disappears, and joint motion is normal, and other objective determinations refer to
Mark normal；
It is effective：After the treatment of 4-6 weeks, the symptom such as pain disappears, and joint motion is unrestricted, other objective determination indexs
It is obviously improved；
Effectively：After the treatment of 4-6 weeks, the symptom such as pain is disappeared substantially, and joint motion is slightly limited, other objective inspections
Looking into index has improvement；
It is invalid：After the treatment of 4-6 weeks, the symptom such as pain and joint motion are not improved, and other objective determinations refer to
Mark is without improvement.
The treatment results of table 1
From the results shown in Table 1, it is provided by the invention treatment arthralgia pain due to rheumatism Chinese medicine composition to rheumatism and its
Pain caused by complication has good alleviation and therapeutic effect.Wherein it is to the effective percentage of arthritis and rheumatic arthritis
70%, it is 76.47% to cervical vertebra ache, dizzy effective percentage, the effective percentage to knee joint and leg arthralgia is
80.00%, the effective percentage to pain in the back is 75.00%, and the total effective rate to arthralgia pain due to rheumatism disease is 75.51%.
The foregoing is only a specific embodiment of the invention, but protection scope of the present invention is not limited thereto, any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all be contained
Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of Chinese medicine composition for treating arthralgia pain due to rheumatism, it is characterised in that the Chinese medicine composition includes following parts by weight
Raw material：Pseudo-ginseng 5-8 parts, tortoise plastron 5-7 parts, root of bidentate achyranthes 5-7 parts, safflower 3-7 parts, seed of cowherb 1-3 parts, prepared rhizome of rehmannia 1-4 parts, reticulate millettia
4-7 parts, rhizome of davallia 2-5 parts, red sage root 5-7 parts, scythian lamb rhizome 1-4 parts, lopseed 1-3 parts, ramulus mori 1-2 parts, shametace 1-4
Part, wintergreen 1-3 parts, cassia twig 1-3 parts, leech 3-5 parts, lycopodium calvatum 1-4 parts, Semen Cuscutae 1-3 parts, saline cistanche 1-5 parts, myrrh 1-
3 parts, Chinese cassia tree 1-4 parts, fleece-flower root 2-5 parts, radix paeoniae rubrathe 3-5 parts, teasel root 2-4 parts, radix glycyrrhizae 3-7 parts, root of three-nerved spicebush 2-4 parts, ground bettle 3-5
Part, frankincense 2-4 parts, Ramulus Taxilli 3-5 parts, Radix Astragali 1-4 parts, pawpaw 2-4 parts and Radix Angelicae Sinensis 2-3 parts.
2. Chinese medicine composition according to claim 1, it is characterised in that the Chinese medicine composition also includes：Pig label grass 2-5
Part, rheum officinale 1-2 parts, iron wire lotus leaf 2-4 parts, bark of eucommia 3-5 parts, anise seed 1-3 parts, fruit of summer cypress 1-3 parts, barrenwort 1-3 parts, shaggy-fruited dittany
Skin 1-3 parts, cortex acanthopanacis 2-3 parts, corydalis tuber 1-3 parts, oldenlandia diffusa 1-2 parts, banksia rose 2-4 parts and ginseng 2-4 parts.
3. Chinese medicine composition according to claim 2, it is characterised in that the Chinese medicine composition includes following parts by weight
Raw material：6 parts of pseudo-ginseng, 6 parts of tortoise plastron, 6 parts of the root of bidentate achyranthes, 5 parts of safflower, 2 parts of the seed of cowherb, 3 parts of prepared rhizome of rehmannia, 5 parts of reticulate millettia, the rhizome of davallia 4
Part, 6 parts of the red sage root, 3 parts of scythian lamb rhizome, 2 parts of lopseed, 1.5 parts of ramulus mori, 3 parts of shametace, 2 parts of wintergreen, 2 parts of cassia twig, water
4 parts of leech, 3 parts of lycopodium calvatum, 2 parts of Semen Cuscutae, 3 parts of saline cistanche, 2 parts of myrrh, 2.5 parts of Chinese cassia tree, 4 parts of the fleece-flower root, 4 parts of the radix paeoniae rubrathe, teasel root 3
Part, 5 parts of radix glycyrrhizae, 3 parts of the root of three-nerved spicebush, 4 parts of ground bettle, 3 parts of frankincense, 4 parts of Ramulus Taxilli, 3 parts of the Radix Astragali, 3 parts of pawpaw, the Fen , pig label of Radix Angelicae Sinensis 2.5
4 parts of grass, 1.5 parts of rheum officinale, 3 parts of iron wire lotus leaf, 4 parts of the bark of eucommia, 2 parts of anise seed, 2 parts of the fruit of summer cypress, 2 parts of barrenwort, 2 parts of the root bark of shaggy-fruited dittany,
3 parts of 2.5 parts of cortex acanthopanacis, 2 parts of corydalis tuber, 1.5 parts of oldenlandia diffusa, 3 parts of the banksia rose and ginseng.
4. the preparation method of the Chinese medicine composition of the treatment arthralgia pain due to rheumatism described in Claims 2 or 3, it is characterised in that the side
Method comprises the following steps：
(1) pseudo-ginseng is taken, dry, pulverize, sieves, obtains Radix Notoginseng powder；Ginseng dry, pulverize, sieve, obtain ginseng pulverate；Take life
Glutinous rehmannia, yellow rice wine wine system, dry, pulverize, and obtain wine cultivated land bloom；
(2) remaining raw material is crushed, sieve, obtain mixed powder, then by the Radix Notoginseng powder obtained in step (1), ginseng pulverate and
Wine cultivated land bloom is well mixed with the mixed powder, adds the alcohol of 4.5-6 times of weight, is soaked 21-30 days, is obtained in steeping in wine
Drug composition；
(3) the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 40-60min, is heated to 60-80 DEG C, it is cold
But, filter, take filtrate, obtain the Chinese medicine composition of the treatment arthralgia pain due to rheumatism.
5. the preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to claim 4, it is characterised in that step
(1) in, pseudo-ginseng is taken, it is less than 10% to be dried at 45-50 DEG C to the moisture in pseudo-ginseng.
6. the preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to claim 4, it is characterised in that step
(1) in, the preparation method of the wine cultivated land bloom is：Radix rehmanniae recen is taken, is cut into slices, adds yellow rice wine, the yellow rice wine and the dried rhizome of rehmannia
Yellow weight ratio is 0.8-1:1,20-30h is stood, treats that yellow rice wine is absorbed by glutinous rehmannia completely, is put into sealing device, at 80-100 DEG C
Boiling 45-60h, it is dry 3-5 days at 40-45 DEG C, 100-200 mesh is crushed to, obtains wine cultivated land bloom.
7. the preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to claim 4, it is characterised in that step
(2) in, the particle diameter of the mixed powder is 60-200 mesh.
8. the preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to claim 4, it is characterised in that step
(2) in, the volume fraction of the alcohol is 75-95%.
9. the preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to claim 4, it is characterised in that step
(3) in, the heating rate of heating is 2-3 DEG C/min.
10. the preparation method of the Chinese medicine composition for the treatment of arthralgia pain due to rheumatism according to claim 4, it is characterised in that step
(3) in, the immersed-in-wine Chinese medicine composition obtained in step (2) is subjected to ultrasonic extraction 40-60min, is heated to 60-80 DEG C, is protected
Warm 2-3h.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108420884A (en) * | 2018-03-28 | 2018-08-21 | 殷学伍 | A kind of Chinese medicine composition for treating rheumatism bone disease |
| CN113786454A (en) * | 2021-09-29 | 2021-12-14 | 北京孔氏中医院 | Composition for eliminating body toxicity of bone meridian diseases and preparation method and application thereof |
| CN118490765A (en) * | 2024-07-15 | 2024-08-16 | 华龙圣爱中医集团有限公司 | Kidney-tonifying wind-dispelling prescription, preparation and application thereof |
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| CN103656238A (en) * | 2013-12-11 | 2014-03-26 | 张娟 | Traditional Chinese medicine composition for treating rheumatic bone diseases |
| CN105616824A (en) * | 2016-03-28 | 2016-06-01 | 常西海 | Bone reunion plaster and preparation method therefor |
| CN107638465A (en) * | 2017-09-28 | 2018-01-30 | 成都市飞龙水处理技术研究所 | A kind of Chinese medicine composition for treating arthralgia and preparation method thereof |
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| CN102648953A (en) * | 2012-03-14 | 2012-08-29 | 孙殿站 | External-use medicinal liquor used for treating rheumatoid bone disease |
| CN103656238A (en) * | 2013-12-11 | 2014-03-26 | 张娟 | Traditional Chinese medicine composition for treating rheumatic bone diseases |
| CN105616824A (en) * | 2016-03-28 | 2016-06-01 | 常西海 | Bone reunion plaster and preparation method therefor |
| CN107638465A (en) * | 2017-09-28 | 2018-01-30 | 成都市飞龙水处理技术研究所 | A kind of Chinese medicine composition for treating arthralgia and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108420884A (en) * | 2018-03-28 | 2018-08-21 | 殷学伍 | A kind of Chinese medicine composition for treating rheumatism bone disease |
| CN113786454A (en) * | 2021-09-29 | 2021-12-14 | 北京孔氏中医院 | Composition for eliminating body toxicity of bone meridian diseases and preparation method and application thereof |
| CN118490765A (en) * | 2024-07-15 | 2024-08-16 | 华龙圣爱中医集团有限公司 | Kidney-tonifying wind-dispelling prescription, preparation and application thereof |
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Application publication date: 20180116 |