CN108245564B - Black plaster and preparation method thereof - Google Patents

Black plaster and preparation method thereof Download PDF

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CN108245564B
CN108245564B CN201810121657.1A CN201810121657A CN108245564B CN 108245564 B CN108245564 B CN 108245564B CN 201810121657 A CN201810121657 A CN 201810121657A CN 108245564 B CN108245564 B CN 108245564B
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root
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CN108245564A (en
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周吉鹏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether

Abstract

The invention discloses a black plaster, which is prepared from the following raw materials: 15-30 parts of nux vomica, 10-20 parts of divaricate saposhnikovia root, 9-20 parts of eucommia bark, 10-20 parts of angelica dahurica, 15-25 parts of achyranthes root, 10-20 parts of unprocessed radix aconiti agrestis, 16-25 parts of pawpaw, 9-20 parts of liquorice, 9-25 parts of fructus psoraleae, 12-25 parts of ligusticum wallichii, 12-25 parts of red paeony root, 10-20 parts of peach kernel and the like. The Chinese herbal medicine preparation of the invention has reasonable formula, and the preparation method comprises the following steps: the black plaster has the characteristics of simple preparation process, convenient carrying and reliable use, and has the effects of quickly relieving pain, dissipating blood stasis and treating nerve pain, wind-cold bone pain and arthralgia and myalgia by absorbing toxic and side effects through transdermal absorption.

Description

Black plaster and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a black plaster and a preparation method thereof.
Background
With the rapid development of social progress, arthralgia, myalgia, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, lumbar muscle strain, bony spur and the like are no longer exclusive to the elderly, and a middle-aged and young-aged population of 20-40 years old also has a considerable part of patients; however, the above diseases belong to aseptic inflammation, the anti-inflammatory drugs do not work, the western medicine treatment depends on methods of pain relief, hormone, sealing, traction, operation and the like, the symptoms are treated, the root causes are not treated, the repetition is easy, the cost is high, the pain of patients is caused, and the physical health of people is seriously influenced.
A plurality of novel and peculiar plasters are available on the market at present, and a legend plaster with national characteristics is also provided. However, the Chinese medicinal materials deviate from the development direction of Chinese medicaments, the traditional Chinese medicaments are not well inherited in the innovation process, hormone medicaments, anesthetics, analgesics and the like are added into the composite medicaments, and the plaster is stuck on a human body and has red swelling, red rash, blister and other pruritus symptoms. Their practice destroys the tradition in traditional Chinese medicine, and makes the traditional Chinese medicine have worse and worse public praise in society.
The Chinese medicine black plaster has the advantages of response; the black plaster has a long history in China, and is proved to be capable of directly influencing a pathological change part through meridians and collaterals through thousands of years of inherited practices, promoting metabolism to adjust yin-yang balance, achieving the effects of easing pain and diminishing inflammation, achieving the effect of externally treating internal diseases, and being more suitable for allergic patients who can not take medicines and take medicines.
Disclosure of Invention
The invention provides a black plaster for safely and effectively treating arthralgia and myalgia and a preparation method thereof. The invention is realized by the following technical scheme:
a black plaster is prepared from the following raw materials: coarse Chinese medicinal materials, fine Chinese medicinal materials, oleum Sesami and Plumbum Preparatium; the traditional Chinese medicine coarse materials comprise the following components in parts by weight: 15-30 parts of nux vomica, 10-20 parts of divaricate saposhnikovia root, 9-20 parts of eucommia bark, 10-20 parts of angelica dahurica, 15-25 parts of achyranthes root, 10-20 parts of unprocessed radix aconiti kusnezoffii, 16-25 parts of pawpaw, 9-20 parts of liquorice, 9-25 parts of fructus psoraleae, 12-25 parts of ligusticum wallichii, 12-25 parts of red paeony root, 10-20 parts of peach kernel, 15-20 parts of lithospermum and 10-20 parts of safflower; the traditional Chinese medicine fine materials are as follows: 16-30 parts of frankincense, 16-30 parts of myrrh, 15-25 parts of asarum and 10-20 parts of native copper; 1000-1500 parts of sesame oil and 400-600 parts of minium.
Preferably, the black plaster is prepared from the following raw materials: coarse Chinese medicinal materials, fine Chinese medicinal materials, oleum Sesami and Plumbum Preparatium; the traditional Chinese medicine coarse materials comprise the following components in parts by weight: 18 parts of nux vomica, 15 parts of divaricate saposhnikovia root, 15 parts of eucommia bark, 15 parts of dahurian angelica root, 20 parts of twotooth achyranthes root, 15 parts of raw common monkshood mother root, 15 parts of raw kusnezoff monkshood root, 22 parts of common floweringquince fruit, 15 parts of liquoric root, 16 parts of malaytea scurfpea fruit, 18 parts of szechuan lovage rhizome, 18 parts of red paeony; the traditional Chinese medicine fine materials are as follows: 22 parts of frankincense, 25 parts of myrrh, 18 parts of asarum and 15 parts of native copper; 1200 parts of sesame oil and 500 parts of minium.
Preferably, the method for preparing the black plaster of the present invention comprises the following steps:
(1) crushing: weighing the traditional Chinese medicine coarse materials according to the weight parts, and cutting or crushing the traditional Chinese medicine coarse materials into small pieces of 1-2 cm; weighing the fine traditional Chinese medicine materials in parts by weight, grinding the fine traditional Chinese medicine materials into powder, and sieving the powder by a 200-mesh sieve;
(2) processing: pouring sesame oil into a pot, placing the crude traditional Chinese medicine materials into the pot, soaking for 7 days, heating with slow fire, gradually heating to 180 ℃, controlling the temperature to be 160-180 ℃ until the traditional Chinese medicine materials in the pot are fried to be black yellow on the surface and brown inside, and filtering out dregs;
(3) boiling: bundling mulberry twigs, willow twigs, sophora japonica twigs, peach twigs and elm twigs into stirring rods, adding the medicinal oil filtered in the step (2) into a pot, continuously and slowly decocting, extracting a little medicinal oil by using the stirring rods made of five twigs when the oil temperature rises to 220 ℃, dripping cold water into the medicinal oil, not dispersing the medicinal oil into beads, finishing decocting the medicinal oil, turning to strong fire to heat the oil to 300-320 ℃, turning to slow fire to remove the minium, adding the minium while stirring, and decocting into viscous black paste;
(4) removing smoke toxicity: after the black paste is prepared by boiling, spraying cold water into the pot for 3 times by turning off the fire, and then continuously stirring after a large amount of black smoke is found;
(5) fire toxin removal: removing smoke toxin, adding the black plaster into cold water basin, stirring, soaking the water-quenched black plaster matrix in cold water, changing water once a day, and taking out after 5 days;
(6) paving: melting the black plaster matrix on a container with slow fire, pouring the fine Chinese medicinal materials into a pot, stirring, spreading the black plaster on plaster cloth with a tool, and press-molding to obtain the final product.
The invention also provides application of the black plaster in preparing a medicine for treating arthralgia and myalgia.
The Chinese herbal medicine prescription of each medicine of the black plaster of the invention:
nux vomica: bitter and warm with strong toxicity, entering liver and spleen meridians, unblocking meridians of the whole body, treating all kinds of arthralgia, dissipating nodulation and relieving swelling.
Wind prevention: dispel wind and relieve exterior syndrome, subdue dampness and relieve pain, relieve spasm and relieve itching.
Eucommia ulmoides: sweet, slightly pungent and warm, entering liver and kidney meridians; tonify liver and kidney, strengthen tendons and bones, prevent abortion. It can be used for treating soreness of waist and knees, sexual impotence, frequent micturition, dribbling urination, rheumatalgia, threatened abortion, and habitual abortion.
Radix angelicae: pungent and warm herbs enter lung, spleen and stomach meridians, dispel wind and remove dampness, relieve pain of orifices, and treat cold headache, brow-edge bone pain, toothache, nasal obstruction, nasosinusitis, chronic diarrhea due to excessive dampness, and leucorrhea with red and white discharge.
Achyranthes root: use raw materials to dissipate blood stasis, eliminate carbuncle and swelling, treat gonorrhea, hematuria, amenorrhea, symptoms, dystocia, coating failure, postpartum blood stasis and abdominal pain, pharyngitis, carbuncle and swelling, traumatic injury. It is used for tonifying liver and kidney, strengthening tendons and bones, treating pain of waist and knees, spasm of limbs, flaccidity and arthralgia.
Radix aconiti: and (3) name registration: aconite, alias: goose, flos Ferulae, WUDU, pungent, bitter and hot with big poison, entering heart, liver, lung and spleen channels, dispelling pathogenic wind and removing dampness, warming channels and relieving pain, and can be used for treating anemofrigid-damp arthralgia, psychroalgia of heart and abdomen, cold hernia pain, anemofrigid-damp arthralgia, etc.
Kusnezoff monkshood root: pungent, bitter and hot taste, heart, liver, kidney and spleen meridians entered, dispelling pathogenic wind and removing dampness, warming meridians and relieving pain, and can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia pain, and anesthesia pain.
Frankincense: promoting blood circulation to alleviate pain, it is used for treating pain of heart and abdomen, spasm of tendons and vessels, traumatic injury, sore and abscess with swelling and pain, and swelling and promoting granulation for external use.
Myrrh: bitter and neutral, with the actions of activating blood, relieving swelling and promoting granulation, it has the actions of activating blood and alleviating pain, so it is indicated for traumatic injuries and is good at activating blood and stretching tendons, dissipating blood and resolving stasis.
Pawpaw: sour, warm enters liver, spleen and stomach meridians; relaxing muscles and tendons, regulating stomach function, and eliminating dampness, and can be used for treating rheumatalgia, soreness of limbs, spasm of tendons and vessels, vomiting, diarrhea, spasm of tendons, loempe, edema, and dysentery.
Licorice root: sweet and neutral. Spleen, stomach, heart and lung meridians regulating the middle warmer and relieving urgency, moistening lung, removing toxicity and harmonizing other drugs, moxibustion is used for treating weakness of spleen and stomach, lassitude, anorexia, abdominal pain, loose stool, extreme pain of limbs contracture, palpitation, dryness of the heart, lung atrophy and cough, and raw for treating sore throat, carbuncle sore and pyogenic infections of children, infantile carbuncle, and drug and food poisoning.
Psoralea fruit: pungent, bitter, warm, entering kidney and spleen meridians; tonifying kidney and yang, consolidating semen and reducing urea, warming spleen and stopping diarrhea, and can be used for treating lumbago due to deficiency-cold, sexual impotence, spermatorrhea, enuresis, frequent micturition, asthma of deficiency type, vitiligo, alopecia areata, and psoriasis.
Ligusticum wallichii: pungent and warm in property, promoting blood circulation and qi, dispelling pathogenic wind and relieving pain, and has effects of promoting blood circulation and removing blood stasis, activating qi-flowing and relieving pain, and dredging blood vessel, and can be used for treating traumatic injury, skin sore, carbuncle, toxic swelling, rheumatalgia, limb pain, and wind cold pain
Red peony root: bitter and slightly cold herbs enter liver and spleen meridians. Clearing heat and cooling blood, promoting blood circulation and removing blood stasis, and can be used for treating pestilence, macula, conjunctival congestion, swelling and pain, carbuncle, sore and carbuncle, amenorrhea, dysmenorrhea, metrorrhagia, leukorrhagia, metrostaxis, costalgia, and traumatic injury.
Peach kernel: break blood and remove stasis, moisten dryness and smooth intestines. It is indicated for amenorrhea, abdominal mass, accumulation of blood in febrile disease, wind arthralgia, traumatic injury, swelling and pain due to blood stasis, blood dryness and constipation.
Lithospermum: sweet in nature and taste, salty and cold in property, entering heart and liver meridians, cooling blood, promoting blood circulation, removing toxic substance and promoting eruption, and can be used for treating blood heat and toxic material, macula purple black, measles without adequate eruption, eczema, and scald caused by water and fire. It can be used for treating warm heat macula, jaundice due to damp-heat pathogen, purpura, emesis, hematuria, stranguria with turbid urine, constipation due to heat accumulation, burn, eczema, and erysipelas.
Safflower: alias: safflower, red thorn safflower, pungent and warm, heart entering, liver meridian activating and meridian dredging, stasis removing and pain relieving, amenorrhea, abdominal mass, dystocia, dead fetus, postpartum lochiorrhea, blood stasis and pain relieving, carbuncle and swelling, traumatic injury.
Asarum: dispel cold, expel wind, alleviate pain, warm lung, resolve retained fluid, dredge orifices.
Native copper: stasis dissipating and pain relieving, reunion of bone and tendon, traumatic injury, broken tendon and fracture, blood stasis and pain.
Sesame oil: the product is sweet and cool in nature and taste, and has the effects of relaxing bowel, detoxifying and promoting tissue regeneration. According to the record of the compendium of materia Medica: has the functions of moistening dryness, detoxifying, relieving pain and reducing swelling.
Minium: can be used for recovering and bonding various comprehensive medicinal efficacy functions, and can penetrate the medicinal efficacy into the deep part of the inner layer of a human body, so that the blood stasis can flow by combining various medicinal efficacies.
Compared with the prior art, the invention has the beneficial effects that: the Chinese herbal medicine preparation of the invention has reasonable formula, and the preparation method comprises the following steps: the black plaster has the characteristics of simple preparation process, convenient carrying and reliable use, and has the effects of quickly relieving pain, dissipating blood stasis and treating nerve pain, wind-cold bone pain and arthralgia and myalgia by absorbing toxic and side effects through transdermal absorption. The traditional Chinese medicine preparation formula is clinically practiced for many years, has obvious drug effect, gives full play to the attributes of all medicinal materials in the process of decocting the plaster, and has the effects of relieving swelling and pain, promoting blood circulation to remove blood stasis, dispelling wind and removing dampness, detoxifying, protecting skin and promoting tissue regeneration on focuses by combining and matching the medicaments in the preparation of the minium ointment. Can achieve the effect of treating both principal and secondary aspect of disease and preventing relapse. The black plaster has good treatment and relief effects on diseases such as arthralgia, neuropathic pain, rheumatic pain of neck, shoulder, waist and leg, has obvious curative effect, has no toxic or side effect in transdermal administration, has safe drug effect, and is worthy of clinical popularization.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1: preparation of black plaster
Weighing the following raw materials in parts by weight: coarse Chinese medicine materials: 150g of nux vomica, 100g of divaricate saposhnikovia root, 90g of eucommia bark, 100g of dahurian angelica root, 150g of twotooth achyranthes root, 100g of unprocessed radix aconiti agrestis, 160g of pawpaw, 90g of liquorice, 90g of fructus psoraleae, 120g of szechuan lovage rhizome, 120g of red paeony root, 100g of peach seed, 150g of sinkiang arn; traditional Chinese medicine fine materials: 160g of frankincense, 160g of myrrh, 150g of asarum and 100g of native copper; sieving with 200 mesh sieve; weighing 10000g of sesame oil and 4000g of minium;
(1) crushing: cutting or crushing the traditional Chinese medicine coarse materials into small pieces of 1-2 cm; pulverizing the above fine materials, and sieving with 200 mesh sieve;
(2) processing: pouring sesame oil into a pot, placing the crude traditional Chinese medicine materials into the pot, soaking for 7 days, heating with slow fire, gradually heating to 180 ℃, controlling the temperature to be 160-180 ℃ until the traditional Chinese medicine materials in the pot are fried to be black yellow on the surface and brown inside, and filtering out dregs;
(3) boiling: bundling mulberry twigs, willow twigs, sophora japonica twigs, peach twigs and elm twigs into stirring rods, adding the medicinal oil filtered in the step (2) into a pot, continuously and slowly decocting, extracting a little medicinal oil by using the stirring rods made of five twigs when the oil temperature rises to 220 ℃, dripping cold water into the medicinal oil, not dispersing the medicinal oil into beads, finishing decocting the medicinal oil, turning to strong fire to heat the oil to 300-320 ℃, turning to slow fire to remove the minium, adding the minium while stirring, and decocting into viscous black paste;
(4) removing smoke toxicity: after the black paste is prepared by boiling, spraying cold water into the pot for 3 times by turning off the fire, and then continuously stirring after a large amount of black smoke is found;
(5) fire toxin removal: removing smoke toxin, adding the black plaster into cold water basin, stirring, soaking the water-quenched black plaster matrix in cold water, changing water once a day, and taking out after 5 days;
(6) paving: melting the black plaster matrix on a container with slow fire, pouring the fine Chinese medicinal materials into a pot, stirring, spreading the black plaster on plaster cloth with a tool, and press-molding to obtain the final product.
Example 2: preparation of Black plaster
Weighing the following raw materials in parts by weight: coarse Chinese medicine materials: 300g of nux vomica, 200g of divaricate saposhnikovia root, 200g of eucommia bark, 200g of angelica dahurica, 250g of twotooth achyranthes root, 200g of unprocessed radix aconiti agrestis, 250g of pawpaw, 200g of liquorice, 250g of fructus psoraleae, 250g of szechuan lovage rhizome, 250g of red paeony root, 200g of peach seed, 200g of lithospermum and 200; the traditional Chinese medicine fine materials are as follows: 300g of frankincense, 300g of myrrh, 250g of asarum and 200g of native copper; 15000g of sesame oil and 6000g of minium.
The black plaster was prepared in the same manner as in example 1.
Example 3: preparation of Black plaster
Weighing the following raw materials in parts by weight: the crude materials of the traditional Chinese medicines are as follows: 180g of nux vomica, 150g of divaricate saposhnikovia root, 150g of eucommia bark, 150g of angelica dahurica, 200g of achyranthes root, 150g of raw radix aconiti agrestis, 220g of pawpaw, 150g of liquorice, 160g of fructus psoraleae, 180g of ligusticum wallichii, 180g of red paeony root, 150g of peach kernel, 180g of lithospermum and 150g of safflower; the traditional Chinese medicine fine materials are as follows: 220g of frankincense, 250g of myrrh, 180g of asarum and 150g of native copper; 12000g of sesame oil and 5000g of minium.
The black plaster was prepared in the same manner as in example 1.
The use method of the black plaster comprises the following steps: after massage or cupping, fresh ginger is used for wiping and pasting the ointment on the surface of skin, the ointment is heated and softened by electric air blowing and then is pasted on an affected part, each plaster is used for 3 days, 10 pastes are taken as a treatment course, and most patients can be cured in 1-3 treatment courses.
Clinical efficacy observation experiment
General data:
220 patients, 94 men and 126 women, the oldest age being 77 years old and the youngest age being 16 years old; among them, 83 persons suffering from rheumatoid arthritis pain, 30 persons suffering from neuropathic pain, 107 persons suffering from neck and shoulder pain, the longest course of disease is 20 years, and the shortest course of disease is 3 days.
The treatment method comprises the following steps:
cleaning the affected part with warm water, massaging or cupping, wiping with fresh rhizoma Zingiberis recens, applying on skin surface, heating and softening with electric blower, and applying on the affected part, wherein each plaster is used for 3 days, and 10 pastes is a treatment course.
The curative effect standard is as follows:
the effect is shown: pain disappeared and joint function improved.
The method has the following advantages: the pain is relieved and the joint function is improved.
And (4) invalidation: the effect is the same as before treatment.
The treatment effect is as follows:
clinical observation shows that the joint nerve pain of a patient pasted with the black plaster is obviously reduced, the function is greatly improved, the treatment effect is approved by the patient, the longest treatment course is 90 days, the shortest treatment course is 2 days, and the specific conditions are shown in a statistical table.
And (3) clinical statistics:
the treatment effect was evaluated according to the treatment effect judgment criteria, and the results are shown in table 1.
Table 1 clinical treatment results table of the invention
Figure DEST_PATH_IMAGE001
The table shows that the total effective rate of the black plaster for treating different diseases is more than 90 percent, which fully indicates that the black plaster has obvious curative effect on arthralgia and neuralgia, has no toxic or side effect in transdermal administration, safe and reliable drug effect.
Typical cases are:
1. when a certain number of women, age 77,
diagnosis: the left knee is slightly red and swollen, the movement is difficult, the pain in the cloudy day is aggravated, and the right knee is still very sore and painful when walking a little though the right knee is improved after the operation;
and (3) diagnosis: synovitis of the left knee
The curative effect is as follows: after the black plaster is pasted for one treatment course, the sick symptoms are obviously improved, the red swelling of the left knee disappears, and the right knee feels powerful when walking but can not walk for a long time; the patient can go to the park to exercise and shop in the market after 3 courses of treatment, and the patient can be used continuously even if the condition of the patient is well improved but the patient is old and sick at a high age.
2. A certain number of years of age 48, male,
diagnosis: cervical vertebra is heavy, the head is dizzy and tired, trigeminal nerve is dull and pain is aggravated in the afternoon and at night; the medicine is normal through X-ray examination and brain CT examination in hospitals and is maintained by the analgesic tablets at ordinary times;
the curative effect is as follows: after the black plaster 1 is pasted, the effect is achieved on the same day, the pain is relieved, the cranial nerve pain obviously improves and disappears after 2 days, the cervical, shoulder, back and cranial nerve pain and the feeling of heaviness of the whole body are completely absent after 3 pastes are continuously used, the night sleep is greatly improved, and the disease does not recur until now after the recovery.
3. Zhangqi, male, age 55,
diagnosis: the neck and shoulder pain is caused by physical work in cement plants throughout the year. The clinical symptoms are stiffness and pain of neck and shoulder, and the hot compress and massage method is commonly used at home, so that a certain relieving effect can be achieved; however, post-throwing does not eradicate the pain and the sensation of soreness and stiffness of the neck and shoulder slowly extends back with age.
The curative effect is as follows: the black plaster is applied to the acupoints of the lumbar vertebra and the shoulder well, each plaster is used for 3 days, and 10 days are a course of treatment; the disease of the patient can be relieved after 1 treatment course of continuous practical use, the curative effect is obvious after 3 treatment courses of continuous use, the work is easy and powerful, and the uncomfortable symptoms disappear completely.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (4)

1. The black plaster is characterized by being prepared from the following raw materials: coarse Chinese medicinal materials, fine Chinese medicinal materials, oleum Sesami and Plumbum Preparatium; the traditional Chinese medicine coarse materials comprise the following components in parts by weight: 15-30 parts of nux vomica, 10-20 parts of divaricate saposhnikovia root, 9-20 parts of eucommia bark, 10-20 parts of angelica dahurica, 15-25 parts of achyranthes root, 10-20 parts of unprocessed radix aconiti kusnezoffii, 16-25 parts of pawpaw, 9-20 parts of liquorice, 9-25 parts of fructus psoraleae, 12-25 parts of ligusticum wallichii, 12-25 parts of red paeony root, 10-20 parts of peach kernel, 15-20 parts of lithospermum and 10-20 parts of safflower; the traditional Chinese medicine fine materials are as follows: 16-30 parts of frankincense, 16-30 parts of myrrh, 15-25 parts of asarum and 10-20 parts of native copper; 1000-1500 parts of sesame oil and 400-600 parts of minium.
2. The black plaster of claim 1, which is prepared from the following raw materials: coarse Chinese medicinal materials, fine Chinese medicinal materials, oleum Sesami and Plumbum Preparatium; the traditional Chinese medicine coarse materials comprise the following components in parts by weight: 18 parts of nux vomica, 15 parts of divaricate saposhnikovia root, 15 parts of eucommia bark, 15 parts of dahurian angelica root, 20 parts of twotooth achyranthes root, 15 parts of raw common monkshood mother root, 15 parts of raw kusnezoff monkshood root, 22 parts of common floweringquince fruit, 15 parts of liquoric root, 16 parts of malaytea scurfpea fruit, 18 parts of szechuan lovage rhizome, 18 parts of red paeony; the traditional Chinese medicine fine materials are as follows: 22 parts of frankincense, 25 parts of myrrh, 18 parts of asarum and 15 parts of native copper; 1200 parts of sesame oil and 500 parts of minium.
3. A method for preparing a black plaster according to claim 1 or 2, comprising the steps of:
(1) crushing: weighing the traditional Chinese medicine coarse materials according to the weight parts, and cutting or crushing the traditional Chinese medicine coarse materials into small pieces of 1-2 cm; weighing the fine traditional Chinese medicine materials in parts by weight, grinding the fine traditional Chinese medicine materials into powder, and sieving the powder by a 200-mesh sieve;
(2) processing: pouring sesame oil into a pot, placing the crude traditional Chinese medicine materials into the pot for soaking, then heating, gradually heating to 180 ℃, controlling the temperature to be 160-180 ℃ until the traditional Chinese medicine materials in the pot are fried to be black yellow on the surface and brown inside, and filtering out dregs;
(3) boiling: bundling mulberry twigs, willow twigs, sophora japonica twigs, peach twigs and elm twigs into stirring rods, adding the medicinal oil filtered in the step (2) into a pot, continuously and slowly decocting, extracting a little medicinal oil when the oil temperature rises to 220 ℃, dripping cold water into the medicinal oil, not dispersing the medicinal oil into beads, finishing decocting the medicinal oil, heating the medicinal oil to 300-320 ℃, turning to mild fire to remove the minium, adding the minium and stirring at the same time, and decocting into a viscous black paste;
(4) removing smoke toxicity: after the mixture is decocted into black paste, cold water is sprayed into the pot for 3 times by turning off the fire, and then the mixture is continuously stirred;
(5) fire toxin removal: removing smoke toxin, adding the black plaster into cold water basin, stirring, soaking the water-quenched black plaster matrix in cold water, changing water once a day, and taking out after 5 days;
(6) paving: melting the black plaster matrix on a container, pouring the fine Chinese medicinal materials into a pot, stirring, spreading the black plaster on a plaster cloth with a tool, and press-molding to obtain the final product.
4. Use of the black plaster of claim 1 or 2 for the preparation of a medicament for the treatment of pain in bones and muscles.
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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101366845A (en) * 2008-09-03 2009-02-18 李富祥 Ointment for treating ache of neck, shoulder, waist and leg
CN101642494A (en) * 2008-11-19 2010-02-10 候贤明 Traditional Chinese medical powder for treating rheumatism and rheumatoid
CN102294008A (en) * 2011-08-30 2011-12-28 杨胜利 Chinese medicine for treating cervical spondylosis, lumbar disc herniation slipped disc, sciatica and femoral head lesion
CN102614265A (en) * 2012-04-26 2012-08-01 河南中医学院 Swelling-diminishing and pain-relieving self-emulsifying ointment
CN103784541A (en) * 2014-02-11 2014-05-14 车金徽 Traditional Chinese medicine for treating pains on neck, shoulders, waist and legs
CN105477089A (en) * 2014-09-29 2016-04-13 熊玮 Bone rheumatism patch for treating osteoporosis

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101366845A (en) * 2008-09-03 2009-02-18 李富祥 Ointment for treating ache of neck, shoulder, waist and leg
CN101642494A (en) * 2008-11-19 2010-02-10 候贤明 Traditional Chinese medical powder for treating rheumatism and rheumatoid
CN102294008A (en) * 2011-08-30 2011-12-28 杨胜利 Chinese medicine for treating cervical spondylosis, lumbar disc herniation slipped disc, sciatica and femoral head lesion
CN102614265A (en) * 2012-04-26 2012-08-01 河南中医学院 Swelling-diminishing and pain-relieving self-emulsifying ointment
CN103784541A (en) * 2014-02-11 2014-05-14 车金徽 Traditional Chinese medicine for treating pains on neck, shoulders, waist and legs
CN105477089A (en) * 2014-09-29 2016-04-13 熊玮 Bone rheumatism patch for treating osteoporosis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
From ethnobotanical uses of Strychnos henningsii to antiinflammatories, analgesics and antispasmodics;Monique Tits et al.;《Journal of Ethnopharmacology》;19911231;第261-267页 *
中药熏蒸治疗痹证152例疗效观察;王宗涛;《国医论坛》;19941231(第4期);第27-28页,尤其是第27页左侧第1-2行、倒数第1-3行,右侧第1-3行 *
中药熏蒸结合鹿瓜多肽注射液治疗骨质增生疗效分析;杨超等;《亚太传统医药》;20130228;第9卷(第2期);第152-153页,尤其是第153页左侧倒数第6-7、18-20行 *

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