CN107536874A - Far infrared bones and tendons injury pain patch and preparation method thereof - Google Patents

Far infrared bones and tendons injury pain patch and preparation method thereof Download PDF

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Publication number
CN107536874A
CN107536874A CN201710630193.2A CN201710630193A CN107536874A CN 107536874 A CN107536874 A CN 107536874A CN 201710630193 A CN201710630193 A CN 201710630193A CN 107536874 A CN107536874 A CN 107536874A
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parts
far infrared
bones
injury pain
patch
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马军超
赵振海
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Anhui Zhongkang Pharmaceutical Co Ltd
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Anhui Zhongkang Pharmaceutical Co Ltd
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Abstract

The invention discloses a kind of far infrared bones and tendons injury pain patch and preparation method thereof, it is related to medical patch field, includes the raw material of following parts by weight:30 40 parts of styrene-isoprene-styrene block copolymer, 20 30 parts of silicon rubber, 5 10 parts of natural rubber, 25 35 parts of light dydrocarbon resin, 27 parts of lanolin, 20 30 parts of cashew nut shell oil, 13 parts of antioxidant, 10 20 parts of polyvinylpyrrolidone, 10 20 parts of lithopone, 5 10 parts of Chinese medicinal powder, 37 parts of far-infared ceramic powder;The Chinese medicinal powder includes the raw material of following parts by weight:10 15 parts of Chinese holly, 5 10 parts of cassia twig, 10 15 parts of the root of Dahurain angelica, 8 12 parts of pseudo-ginseng, 5 10 parts of folium cortex eucommiae, 5 10 parts of decumbent corydalis tuber.Patch agent prepared by the present invention reduces excitant and the allergic reaction of traditional rubber patch well, initial bonding strength and holding power are good, it is not easily stripped, and do not stay cull, viscosity strong after peeling off, available for muscle and bone ache, pain in waist and lower extremities, muscle arthrosis ache, sprain, the auxiliary treatment of bones and tendons injury pain caused by cervical spondylopathy, osteoproliferation, extremity numbness etc..

Description

Far infrared bones and tendons injury pain patch and preparation method thereof
Technical field
The present invention relates to medical patch technical field, more particularly to a kind of far infrared bones and tendons injury pain patch and preparation method thereof.
Background technology
Far-infared ceramic powder is a kind of white powder, is mixed by many kinds of substance, and it has good Far infrared heat Effect, the far infrared that wavelength is 4-14 microns can be discharged, is easily absorbed by the body, enlivens matrix, and imitate by far infrared It should distend the blood vessels, accelerate blood circulation, strengthen body local metabolism, improve microcirculation, play the ailing effect of link. The patch agent produced using far-infared ceramic powder can be found everywhere.At present, the patch of domestic production is mostly rubber ointment, and it is used Traditional matrices composition of raw materials in, widely used natural rubber is as framework material.Rubber ointment adhesion is strong, easy to use, The effect of local treatment and whole body therapeutic is played by Transdermal absorption, drug effect is notable.But rubber ointment clinically uses process In there is also certain limitation, the mainly excitant to skin and allergic reaction, symptom mainly has skin to itch, inflammation, rise Pimple, long bubble, can cause anaphylactic shock when serious, so as to reduce the comfortableness of rubber ointment, security and validity. In addition, iliacus Shang Tong Tie is often affixed on joint, for ensure daily bending motion be will not alice, come off, adhesion strength is larger, this Cutaneous pain when sample can cause to peel off, and in order to avoid skin is stimulated by colloid, polar substances are typically free of in matrix components, no It is ventilative, it can be influenceed when largely perspiring conformable.As important exterior-applied formulation, emplastrum is more and more paid attention to, and improves base Matter, strengthen its comfort, it is vital to improve curative effect.
The content of the invention
Based on technical problem existing for background technology, the present invention proposes a kind of far infrared bones and tendons injury pain patch and its preparation side Method, the patch agent of preparation uses comfortably, small to skin irritation.
A kind of far infrared bones and tendons injury pain patch proposed by the present invention, include the raw material of following parts by weight:Styrene-isoamyl two Alkene-styrene block copolymer 30-40 parts, silicon rubber 20-30 parts, light dydrocarbon resin 25-35 parts, lanolin 2-7 parts, cashew nut shell oil It is 20-30 parts, antioxidant 1-3 parts, polyvinylpyrrolidone 10-20 parts, lithopone 10-20 parts, Chinese medicinal powder 5-10 parts, remote red Outer ceramic powder 3-7 parts;
The Chinese medicinal powder includes the raw material of following parts by weight:Chinese holly 10-15 parts, cassia twig 5-10 parts, root of Dahurain angelica 10-15 Part, pseudo-ginseng 8-12 parts, folium cortex eucommiae 5-10 parts, decumbent corydalis tuber 5-10 parts.
Preferably, far infrared bones and tendons injury pain pastes, and includes the raw material of following parts by weight:Styrene-isoprene-phenylethene is embedding It is section copolymer 32-37 parts, silicon rubber 25-30 parts, light dydrocarbon resin 27-32 parts, lanolin 4-6 parts, cashew nut shell oil 24-28 parts, anti- Oxidant 1-3 parts, polyvinylpyrrolidone 14-18 parts, lithopone 10-15 parts, Chinese medicinal powder 5-8 parts, far-infared ceramic powder 4-7 Part.
Preferably, the preparation method of the Chinese medicinal powder is as follows:Take Chinese holly, cassia twig, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, summer Nothing, the water boiling and extraction 1-3h of 6-10 times of medicinal material initial mass is added, filtering, Aqueous extracts filter residue with together with is obtained, to one of filter residue Middle 70% ethanol solution for adding 4-8 times of medicinal material initial mass, refluxing extraction 1-3h, filtering, obtains alcohol extract, merge Aqueous extracts and Alcohol extract, it is concentrated under reduced pressure, is dried in vacuo, obtains Chinese medicinal powder.
The preparation method of far infrared far infrared bones and tendons injury pain patch, comprises the following steps:
S1, SIS, silicon rubber, light dydrocarbon resin, cashew nut shell oil be added to In high mixer, melt blending, mixture A is obtained;
S2, lithopone, lanolin, antioxidant, polyvinylpyrrolidone are added into mixture A, be stirred, obtain mixed Compound B;
S3, Chinese medicinal powder, far-infared ceramic powder are added into mixture B, be stirred, obtain mixture C;
S4, mixture C cooled, constant temperature coating, lid lining, section, produced.
Preferably, melt blending temperature is 120-130 DEG C in the step S1.
Preferably, it is stirred 1-2h in the step S1.
Preferably, it is stirred 0.5-1.5h in the step S2.
Preferably, it is stirred 20-40min in the step S3.
Preferably, it is cooled to 95-100 DEG C in the step S4.
Using technical scheme, it has advantage and effect following prominent:The present invention selects styrene-isoamyl The framework material of styrene block copolymer and silicon rubber as patch agent, there is good initial bonding strength and peel strength; Light dydrocarbon resin has good tackifying, compatibility and heat resistance, can improve the heat resistance and flexibility of matrix;Cashew nut shell oil Composition in both contain polar group phenolic hydroxyl group, also containing non-polar group carbon-carbon double bond, there is good compatibility, and long-chain Structure can improve the flexibility of matrix, improve dispersiveness of the lithopone in matrix, improve caking property and resistance to flaking, and cashew nut Shell oil cost is relatively low, renewable;Polyvinyl pyridine alkanone has good biocompatibility, can to skin without any stimulation The hydrophily of matrix is improved, matrix is moistened in skin surface, strengthens comfort;Make in the far infrared of far-infared ceramic powder Under, Chinese medicinal powder is more easy to be absorbed by Cutaneous permeation, and Chinese holly is clearing heat and detoxicating, subsiding swelling and resolving stagnation, cassia twig relieving muscles diaphoresis, Warming meridians and promoting circulation of qi, helps yang transforming qi, the dehumidifying of angelica dahurica powder wind, sensible analgesic, detumescence and apocenosis, pseudo-ginseng dissipate stasis of blood hemostasis, detumescence ding-tong, folium cortex eucommiae Filling liver kidney, strengthening the bones and muscles, decumbent corydalis tuber promoting blood circulation, dredging collateral, promoting qi circulation and relieving pain, each drug ingedient synergy, promoting blood circulation and removing obstruction in channels, scattered stasis detumescence, Patch agent prepared by the present invention reduces the excitant and allergic reaction, initial bonding strength and holding power of traditional rubber patch well Good, plasticity is preferable, and viscosity is good, strong with skin affinity, more easily peelable compared with traditional natural rubber patch agent, and after stripping Cull is not stayed, drugloading rate is big, and available for muscle and bone ache, pain in waist and lower extremities, muscle arthrosis ache, sprain, cervical spondylopathy, osteoproliferation, limbs The auxiliary treatment of bones and tendons injury pain caused by numbness etc..
Embodiment
Below, technical scheme is described in detail by specific embodiment.
Embodiment 1
A kind of far infrared bones and tendons injury pain patch, include the raw material of following parts by weight:Styrene-isoprene-phenylethene block 40 parts of copolymer, 20 parts of silicon rubber, 35 parts of light dydrocarbon resin, 2 parts of lanolin, 30 parts of cashew nut shell oil, 1 part of antioxidant, polyethylene 20 parts of pyrrolidones, 10 parts of lithopone, 10 parts of Chinese medicinal powder, 3 parts of far-infared ceramic powder.Wherein, Chinese medicinal powder is by Chinese holly, osmanthus Branch, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber are according to 15:7:15:8:10:5 mass ratio composition.
Embodiment 2
A kind of far infrared bones and tendons injury pain patch, include the raw material of following parts by weight:Styrene-isoprene-phenylethene block 30 parts of copolymer, 30 parts of silicon rubber, 25 parts of light dydrocarbon resin, 7 parts of lanolin, 20 parts of cashew nut shell oil, 3 parts of antioxidant, polyethylene 10 parts of pyrrolidones, 20 parts of lithopone, 5 parts of Chinese medicinal powder, 7 parts of far-infared ceramic powder.
Wherein, Chinese medicinal powder by Chinese holly, cassia twig, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber according to 10:10:10:12:5: 10 mass ratio composition, its preparation method are as follows:Chinese holly, cassia twig, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber are taken, adds medicinal material The water boiling and extraction 3h of 8 times of initial mass, filtering, obtains Aqueous extracts filter residue with together with, and it is initial that 6 times of medicinal materials are added into one of filter residue 70% ethanol solution of quality, refluxing extraction 2h, filtering, alcohol extract is obtained, merge Aqueous extracts and alcohol extract, be concentrated under reduced pressure, vacuum Dry, obtain Chinese medicinal powder.
Embodiment 3
A kind of far infrared bones and tendons injury pain patch, include the raw material of following parts by weight:Styrene-isoprene-phenylethene block 35 parts of copolymer, 25 parts of silicon rubber, 30 parts of light dydrocarbon resin, 5 parts of lanolin, 30 parts of cashew nut shell oil, 2 parts of antioxidant, polyethylene 18 parts of pyrrolidones, 14 parts of lithopone, 7 parts of Chinese medicinal powder, 4 parts of far-infared ceramic powder;Wherein, Chinese medicinal powder is by Chinese holly, osmanthus Branch, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber are according to 12:10:12:9:7:7 mass ratio composition.
The preparation method of far infrared far infrared bones and tendons injury pain patch, comprises the following steps:
S1, SIS, silicon rubber, light dydrocarbon resin, cashew nut shell oil be added to In high mixer, melt blending, mixture A is obtained;
S2, lithopone, lanolin, antioxidant, polyvinylpyrrolidone are added into mixture A, be stirred, obtain mixed Compound B;
S3, Chinese medicinal powder, far-infared ceramic powder are added into mixture B, be stirred, obtain mixture C;
S4, by mixture C cool 100 DEG C, constant temperature coating, lid lining, section, produce.
Embodiment 4
A kind of far infrared bones and tendons injury pain patch, include the raw material of following parts by weight:Styrene-isoprene-phenylethene block 32 parts of copolymer, 28 parts of silicon rubber, 25 parts of light dydrocarbon resin, 5 parts of lanolin, 22 parts of cashew nut shell oil, 1 part of antioxidant, polyethylene 14 parts of pyrrolidones, 12 parts of lithopone, 6 parts of Chinese medicinal powder, 6 parts of far-infared ceramic powder;
The preparation method of far infrared far infrared bones and tendons injury pain patch, comprises the following steps:
S1, according to 11:8:12:9:10:6 mass ratio, Chinese holly, cassia twig, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber are taken, The water boiling and extraction 1.5h of 10 times of medicinal material initial mass is added, filtering, Aqueous extracts filter residue with together with is obtained, is added into one of filter residue 70% ethanol solution of 8 times of medicinal material initial masses, refluxing extraction 1.5h, filtering, alcohol extract is obtained, merges Aqueous extracts and alcohol extract, It is concentrated under reduced pressure, is dried in vacuo, obtains Chinese medicinal powder.
S2, SIS, silicon rubber, light dydrocarbon resin, cashew nut shell oil be added to In high mixer, the melt blending at 120 DEG C, stirring reaction 1h, mixture A is obtained;
S3, lithopone, lanolin, antioxidant, polyvinylpyrrolidone are added into mixture A, are stirred 1.5h, Obtain mixture B;
S4, Chinese medicinal powder, far-infared ceramic powder are added into mixture B, be stirred 20min, obtain mixture C;
S5, by mixture C cool 95 DEG C, constant temperature coating, lid lining, section, produce.
Embodiment 5
A kind of far infrared bones and tendons injury pain patch, include the raw material of following parts by weight:Styrene-isoprene-phenylethene block 34 parts of copolymer, 27 parts of silicon rubber, 30 parts of light dydrocarbon resin, 5 parts of lanolin, 26 parts of cashew nut shell oil, 2 parts of antioxidant, polyethylene 16 parts of pyrrolidones, 14 parts of lithopone, 7 parts of Chinese medicinal powder, 5 parts of far-infared ceramic powder.
The preparation method of far infrared far infrared bones and tendons injury pain patch, comprises the following steps:
S1, according to 12:8:12:10:7:7 mass ratio, Chinese holly, cassia twig, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber are taken, The water boiling and extraction 2h of 8 times of medicinal material initial mass is added, filtering, obtains Aqueous extracts filter residue with together with, 6 times are added into one of filter residue 70% ethanol solution of medicinal material initial mass, refluxing extraction 2h, filtering, alcohol extract is obtained, merge Aqueous extracts and alcohol extract, decompression is dense Contracting, vacuum drying, obtains Chinese medicinal powder.
S2, SIS, silicon rubber, light dydrocarbon resin, cashew nut shell oil be added to In high mixer, the melt blending at 125 DEG C, stirring reaction 1.5h, mixture A is obtained;
S3, lithopone, lanolin, antioxidant, polyvinylpyrrolidone are added into mixture A, be stirred 1h, obtain Mixture B;
S4, Chinese medicinal powder, far-infared ceramic powder are added into mixture B, be stirred 30min, obtain mixture C;
S5, by mixture C cool 100 DEG C, constant temperature coating, lid lining, section, produce.
Embodiment 6
A kind of far infrared bones and tendons injury pain patch, include the raw material of following parts by weight:Styrene-isoprene-phenylethene block 36 parts of copolymer, 25 parts of silicon rubber, 32 parts of light dydrocarbon resin, 6 parts of lanolin, 24 parts of cashew nut shell oil, 2 parts of antioxidant, polyethylene 18 parts of pyrrolidones, 15 parts of lithopone, 8 parts of Chinese medicinal powder, 6 parts of far-infared ceramic powder;
The preparation method of far infrared far infrared bones and tendons injury pain patch, comprises the following steps:
S1, according to 14:7:11:11:8:8 mass ratio, Chinese holly, cassia twig, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber are taken, The water boiling and extraction 2.5h of 8 times of medicinal material initial mass is added, filtering, Aqueous extracts filter residue with together with is obtained, 6 is added into one of filter residue 70% ethanol solution of times medicinal material initial mass, refluxing extraction 2h, filtering, alcohol extract is obtained, merge Aqueous extracts and alcohol extract, decompression Concentration, vacuum drying, obtains Chinese medicinal powder.
S2, SIS, silicon rubber, light dydrocarbon resin, cashew nut shell oil be added to In high mixer, the melt blending at 120 DEG C, stirring reaction 1.5h, mixture A is obtained;
S3, lithopone, lanolin, antioxidant, polyvinylpyrrolidone are added into mixture A, be stirred 50min, obtain mixture B;
S4, Chinese medicinal powder, far-infared ceramic powder are added into mixture B, be stirred 30min, obtain mixture C;
S5, by mixture C cool 95 DEG C, constant temperature coating, lid lining, section, produce.
Contrast test:
The raw material of following parts by weight is taken respectively, the preparation for traditional far infrared bones and tendons injury pain patch:78 parts of natural rubber, stand 50 parts of moral powder, 50 parts of zinc oxide, 27 parts of rosin, 5 parts of vaseline, 3 parts of lanolin, 1.2 parts of rubber antioxidant, far-infared ceramic powder 9 parts, 12 parts of Chinese medicinal powder.Wherein, the preparation method of Chinese medicinal powder is prepared according to the formula in embodiment 5.
Preparation method:Natural rubber is taken, is dried, is cut into bulk, is plasticated in rubber mixing machine and reticulate thin slice, eliminates electrostatic, It is dipped in appropriate gasoline, is moved to after being swelled in adhesive supplier, stirred evenly, adds vaseline, lanolin, zinc oxide, rosin, vertical by several times Matrix is made in moral powder, rubber antioxidant, adds the Chinese medicinal powder made, far-infared ceramic powder, stirs evenly, and applies cream, reclaims gasoline, Lid lining, section, is produced.
Patch agent prepared by embodiment and patch agent made from contrast test are subjected to following performance detection:
1st, initial bonding strength detects:According to GB4852-84 standard testings, tested using 6# steel balls;
2nd, holding power detects:According to GB4851-84 standard testings;
3rd, peel strength detects:According to GB2792-81 standard testings.
4th, sensitization detects:Healthy white rat 90 is chosen, is divided into three groups, every group awards patch embodiment 5,6 and right respectively The patch agent prepared than experiment, using androgynous left and right sides self-contrast method, back spinal both sides hair is shaved off, area is 2cmx2cm, patch agent is attached to left side and goes to hair-fields, changes patch agent every 24h, and observe surface skin whether there is erythema, oedema Deng allergic phenomena.
Testing result is shown in Table 1.
It is observed that patch agent rat experiment group prepared by the embodiment of the present invention 5 and embodiment 6, the skin thing of recipient site Without allergic phenomenas such as any erythema and oedema, and contrast test group has the slightly aobvious edema of 1 skin, has small red dot on 1, this says Patch agent sensitization prepared by the bright embodiment of the present invention is weak, small to skin irritation.In addition, as can be seen from Table 1, the present invention The initial bonding strength and holding power of patch agent prepared by embodiment 5 and embodiment 6 will be substantially better than the cream that in contrast test prepared by tradition Patch, peel strength is slightly smaller, and moulding preferably modest viscosity, affinity is strong, without dermal sensation is pullled when movable, uses Feel without discomfort, it is more easily peelable;And plasticity is general in contrast test, the sensation of skin is slightly pullled when movable, patch is over time Have a uncomfortable sensation, docile position have it is even have itch sensation, and slightly pain when peeling off is relatively difficult during stripping.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto, Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.

Claims (9)

1. a kind of far infrared bones and tendons injury pain patch, it is characterised in that include the raw material of following parts by weight:Styrene-isoprene-benzene Ethylene block copolymer 30-40 parts, silicon rubber 20-30 parts, light dydrocarbon resin 25-35 parts, lanolin 2-7 parts, cashew nut shell oil 20-30 Part, antioxidant 1-3 parts, polyvinylpyrrolidone 10-20 parts, lithopone 10-20 parts, Chinese medicinal powder 5-10 parts, far infrared pottery Porcelain powder 3-7 parts;
The Chinese medicinal powder includes the raw material of following parts by weight:Chinese holly 10-15 parts, cassia twig 5-10 parts, root of Dahurain angelica 10-15 parts, three Seven 8-12 parts, folium cortex eucommiae 5-10 parts, decumbent corydalis tuber 5-10 parts.
2. a kind of far infrared bones and tendons injury pain patch as claimed in claim 1, it is characterised in that include the raw material of following parts by weight: SIS 32-37 parts, silicon rubber 25-30 parts, light dydrocarbon resin 27-32 parts, lanolin 4-6 parts, cashew nut shell oil 24-28 parts, antioxidant 1-3 parts, polyvinylpyrrolidone 14-18 parts, lithopone 10-15 parts, Chinese medicine Medicinal powder 5-8 parts, far-infared ceramic powder 4-7 parts.
A kind of 3. far infrared bones and tendons injury pain patch as claimed in claim 1, it is characterised in that the preparation method of the Chinese medicinal powder It is as follows:Chinese holly, cassia twig, the root of Dahurain angelica, pseudo-ginseng, folium cortex eucommiae, decumbent corydalis tuber are taken, adds the water boiling and extraction of 6-10 times of medicinal material initial mass 1-3h, filtering, obtains Aqueous extracts filter residue with together with, and 70% ethanol solution of 4-8 times of medicinal material initial mass is added into one of filter residue, Refluxing extraction 1-3h, filtering, alcohol extract is obtained, merge Aqueous extracts and alcohol extract, be concentrated under reduced pressure, be dried in vacuo, obtain Chinese medicinal powder.
4. the preparation method of the far infrared far infrared bones and tendons injury pain patch as described in claim 1-3 is any, it is characterised in that including Following steps:
S1, SIS, silicon rubber, light dydrocarbon resin, cashew nut shell oil be added to it is high mixed In machine, melt blending, mixture A is obtained;
S2, lithopone, lanolin, antioxidant, polyvinylpyrrolidone are added into mixture A, be stirred, obtain mixture B;
S3, Chinese medicinal powder, far-infared ceramic powder are added into mixture B, be stirred, obtain mixture C;
S4, mixture C cooled, constant temperature coating, lid lining, section, produced.
5. the preparation method of far infrared far infrared bones and tendons injury pain patch as claimed in claim 4, it is characterised in that the step S1 Middle melt blending temperature is 120-130 DEG C.
6. the preparation method of far infrared far infrared bones and tendons injury pain patch as claimed in claim 4, it is characterised in that the step S1 In be stirred 1-2h.
7. the preparation method of far infrared far infrared bones and tendons injury pain patch as claimed in claim 4, it is characterised in that the step S2 In be stirred 0.5-1.5h.
8. the preparation method of far infrared far infrared bones and tendons injury pain patch as claimed in claim 4, it is characterised in that the step S3 In be stirred 20-40min.
9. the preparation method of far infrared far infrared bones and tendons injury pain patch as claimed in claim 4, it is characterised in that the step S4 In be cooled to 95-100 DEG C.
CN201710630193.2A 2017-07-28 2017-07-28 Far infrared bones and tendons injury pain patch and preparation method thereof Pending CN107536874A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114569697A (en) * 2022-03-28 2022-06-03 河南省洛阳正骨医院(河南省骨科医院) Traditional Chinese medicine extract for treating arthralgia syndrome type cervical spondylosis and gel patch thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105726513A (en) * 2014-12-10 2016-07-06 安徽省德济堂药业有限公司 Far-infrared inflammation diminishing and pain alleviating patch

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105726513A (en) * 2014-12-10 2016-07-06 安徽省德济堂药业有限公司 Far-infrared inflammation diminishing and pain alleviating patch

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114569697A (en) * 2022-03-28 2022-06-03 河南省洛阳正骨医院(河南省骨科医院) Traditional Chinese medicine extract for treating arthralgia syndrome type cervical spondylosis and gel patch thereof

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Application publication date: 20180105