CN107485732A - The preparation method of antimicrobial silicon sebific duct, composite antibacterial material and the material in silicone tube surface coating - Google Patents
The preparation method of antimicrobial silicon sebific duct, composite antibacterial material and the material in silicone tube surface coating Download PDFInfo
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- CN107485732A CN107485732A CN201610401689.8A CN201610401689A CN107485732A CN 107485732 A CN107485732 A CN 107485732A CN 201610401689 A CN201610401689 A CN 201610401689A CN 107485732 A CN107485732 A CN 107485732A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
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- A—HUMAN NECESSITIES
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/04—Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases
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Abstract
The invention discloses a kind of antimicrobial silicon sebific duct, composite antibacterial material and the material in the preparation method of silicone tube surface coating, and the antimicrobial silicon sebific duct includes silica gel tube body and be covered in the nano silver-carrying titanium dioxide chitosan composite antibacterial material layer of the silicone tube body surface.The composite antibacterial material, it is characterised in that the composite antibacterial material is nano silver-carrying titanium dioxide chitosan composite antibacterial material, including is made up of the raw material of following weight：Nano silver-carrying titanium dioxide 0.1 0.2, the silane couplers 0.05 0.1 of KH 550, chitosan 0.2 0.3.This antimicrobial silicon sebific duct is safe, and cost is cheap；This composite antibacterial material is easily prepared, not easy oxidation discoloration；This preparation method can make the firm coating of anti-biotic material in silica gel pipe surface without easy to fall off, and anti-biotic material consumes small, low manufacture cost.
Description
Technical field
The present invention relates to antibacterial silica gel, anti-biotic material field, and in particular to a kind of preparation method of antimicrobial silicon sebific duct, composite antibacterial material and the material in silicone tube surface coating.
Background technology
Silica gel material is good with tissue compatibility due to not having toxic side effect to human body, often by as the various medicine equipment raw material of manufacture.Common silica gel material does not have antibacterial functions, therefore these silica gel medicine equipments, under the special environment that carries disease germs, without antibacterial action, and there is Nano Silver stronger antibacterial action to be finalized.
Conventional antimicrobial silicon sebific duct is used as anti-biotic material using addition or coating antibiotic, sodium rice silver.The silicone tube that addition or coating antibiotic make, long-term use easily causes human flora to lack of proper care, and causes pathogenic bacteria to produce drug resistance, and for this kind of medicine equipment using antibiotic, country strictly controls its production；Surface coated with nano ag material silicone tube, because the middle silver ion of Nano Silver is tiny, very easy oxidation is changed into black, influences silica gel tube exterior and performance so as to cause silica gel pipe surface modified；And sodium rice silver anti-biotic material is directly added into mixed-forming silicone tube in silica gel material, anti-biotic material consumption is big, and cost of manufacture is high.
The content of the invention
The present invention seeks in view of the shortcomings of the prior art, and provide a kind of preparation method of antimicrobial silicon sebific duct, composite antibacterial material and the material in silicone tube surface coating.This antimicrobial silicon sebific duct is safe, and cost is cheap；This composite antibacterial material is easily prepared, not easy oxidation discoloration；This preparation method can make the firm coating of anti-biotic material in silica gel pipe surface without easy to fall off, and anti-biotic material consumes small, low manufacture cost.
Realizing the technical scheme of the object of the invention is：
A kind of antimicrobial silicon sebific duct, including silica gel tube body and the nano silver-carrying titanium dioxide-chitosan composite antibacterial material layer for being covered in the silicone tube body surface.
The antimicrobial silicon sebific duct is antibacterial silica gel catheter, antibacterial silica gel drainage tube or antibacterial silica gel connecting tube.
A kind of composite antibacterial material, the composite antibacterial material is nano silver-carrying titanium dioxide-chitosan composite antibacterial material, including is made up of the raw material of following weight：Nano silver-carrying titanium dioxide 0.1-0.2 parts, KH-550 silane coupler 0.05-0.1 parts, chitosan 0.2-0.3 parts.
Nano silver-carrying titanium dioxide-chitosan the composite antibacterial material silicone tube surface coating preparation method, including：
1st, Silica Surface modification
（1）Silica Surface activity treatment fluid is prepared：
By weight ratio, in every 10 parts of Silica Surfaces activity treatment fluid, containing 1 part of 95% aqueous isopropanol, double two or four vulcanizing agent 0.1-0.2 parts, crosslinking agent UN-125F 0.08-0.15 parts, remaining is deionized water；
（2）Carry out surface modification treatment：
The silica gel being newly molded is put into after soaking the 20-30 seconds in the Silica Surface activity treatment fluid for be heated to 45-55 DEG C and taken out, airing is standby；
2nd, nano silver-carrying titanium dioxide-chitosan composite antibacterial material mixed solution is prepared
（1）By weight ratio, in every 10 parts of nano silver-carryings titanium dioxide dispersion mixed solution, nano silver-carrying titanium dioxide 0.1-0.2 parts, KH-550 silane coupler 0.05-0.1 parts, chitosan 0.2-0.3 parts, remaining is deionized water；
（2）The preparation of composite dispersion mixed solution
First nano silver-carrying titanium dioxide is added in appropriate amount of deionized water, heating water bath is to 75-85 DEG C, stirring 5 minutes, KH-550 silane couplers are added, 2% ammoniacal liquor, which is added dropwise, makes pH value be 8-9, stirs 10 minutes, add chitosan, 2% watery hydrochloric acid, which is added dropwise, makes pH value stir 5-10 minutes up to being 6-7.5, nano silver-carrying titanium dioxide-chitosan composite dispersion mixed solution is made；
3rd, silica gel of the step 1 Jing Guo surface modification treatment is put into the nano silver-carrying titanium dioxide-chitosan composite dispersion mixed solution for being heated to 65-75 DEG C, carries out coating and soak 3 minutes, take out airing；
4th, the silica gel after step 3 being handled is put into curing cage, and 170-180 DEG C of temperature vulcanizes 5 hours, completes preparation of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone tube surface coating.Obtain antibacterial silica gel catheter of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone catheter surface coating.
The preparation method of this antimicrobial silicon sebific duct is applied to antibacterial silica gel catheter, antibacterial silica gel drainage tube, antibacterial silica gel connecting tube etc..
This antimicrobial silicon sebific duct is safe, and cost is cheap；This composite antibacterial material is easily prepared, not easy oxidation discoloration；This preparation method can make the firm coating of anti-biotic material in silica gel pipe surface without easy to fall off, and anti-biotic material consumes small, low manufacture cost.
Brief description of the drawings
Fig. 1 is the cross-sectional view of antibacterial silicone tube in embodiment.
In figure, the anti-biotic material layer of 1. silica gel tube body 2..
Embodiment
Below by being further elaborated in conjunction with the accompanying drawings and embodiments to present invention, but it is not limitation of the invention.
Embodiment 1：
As shown in figure 1, a kind of antimicrobial silicon sebific duct, including silica gel tube body 1 and the nano silver-carrying titanium dioxide-chitosan composite antibacterial material layer 2 for being covered in the surface of silica gel tube body 1.
The antimicrobial silicon sebific duct is antibacterial silica gel catheter.
Nano silver-carrying titanium dioxide-chitosan the composite antibacterial material, including be made up of the raw material of following weight：Nano silver-carrying titanium dioxide 0.2, KH-550 silane couplers 0.1, chitosan 0.3.
Nano silver-carrying titanium dioxide-chitosan the composite antibacterial material silicone catheter surface coating preparation method, including：
1st, according to a conventional method silicone catheter extrusion molding；
2nd, silicone catheter surface modification treatment
（1）Silica Surface activity treatment fluid is prepared：
95% aqueous isopropanol 1000ml, 200 grams of double two or four vulcanizing agents, 150 grams of crosslinking agent UN-125F are separately added into 10kg deionized waters, is stirred and evenly mixed, it is standby；
（2）The silicone catheter newly extruded is put into after being soaked 30 seconds in the Silica Surface activity treatment fluid for be heated to 55 DEG C and taken out, airing；
3rd, nano silver-carrying titanium dioxide-chitosan composite antibacterial material mixed solution is prepared
（1）Nano silver-carrying titanium dioxide 200g is weighed, adds deionized water 1000ml, heating water bath is to 85 DEG C, stirring 5 minutes, it is 9 to add KH-550 silane couplers 100ml, 2% ammoniacal liquor regulation pH value is added dropwise, and is stirred 10 minutes, place 20 minutes, nano silver-carrying titanium dioxide dispersion mixed solution is made；
（2）Chitosan 300g is weighed, is added in above-mentioned nano silver-carrying titanium dioxide dispersion mixed solution, it is 6 that 2% watery hydrochloric acid regulation pH value, which is added dropwise, heating water bath is to 75 DEG C, stirring 5 minutes, add deionized water that nano silver-carrying titanium dioxide-chitosan composite antibacterial solution is made to 10000ml；
4th, the silicone catheter Jing Guo surface-active-treatment is put into the nano silver-carrying titanium dioxide with heating water bath to 75 DEG C-chitosan composite antibacterial solution, soaked 3 minutes, take out airing；
5th, the silicone catheter after step 4 being handled is put into curing cage, and 170 DEG C vulcanize 5 hours, completes preparation of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone catheter surface coating.Obtain antibacterial silica gel catheter of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone catheter surface coating.
Silicone catheter through above-mentioned nano silver-carrying titanium dioxide-chitosan composite antibacterial material coating, is antibacterial silica gel catheter, and its antibacterial bacteriostatic rate is up to 95.6%.
Silicone catheter silica gel drainage tube, connecting silicone pipe are replaced, antibacterial silica gel drainage tube, antibacterial silica gel connecting tube is made.
Embodiment 2：
As shown in figure 1, a kind of antimicrobial silicon sebific duct, including silica gel tube body 1 and the nano silver-carrying titanium dioxide-chitosan composite antibacterial material layer 2 for being covered in the surface of silica gel tube body 1.
The antimicrobial silicon sebific duct is antibacterial silica gel catheter.
Nano silver-carrying titanium dioxide-chitosan the composite antibacterial material, including be made up of the raw material of following weight：Nano silver-carrying titanium dioxide 0.1, KH-550 silane couplers 0.05, chitosan 0.2.
Nano silver-carrying titanium dioxide-chitosan the composite antibacterial material silicone catheter surface coating preparation method, including：
1st, according to a conventional method silicone catheter extrusion molding；
2nd, silicone catheter surface modification treatment
（1）Silica Surface activity treatment fluid is prepared：
95% aqueous isopropanol 1000ml, 100 grams of double two or four vulcanizing agents, 80 grams of crosslinking agent UN-125F are separately added into 10kg deionized waters, is stirred and evenly mixed, it is standby；
（2）The silicone catheter newly extruded is put into after being soaked 20 seconds in the Silica Surface activity treatment fluid for be heated to 45 DEG C and taken out, airing；
3rd, nano silver-carrying titanium dioxide-chitosan composite antibacterial material mixed solution is prepared
（1）Nano silver-carrying titanium dioxide 100g is weighed, adds deionized water 1000ml, heating water bath is to 75 DEG C, stirring 5 minutes, it is 8 to add KH-550 silane couplers 50ml, 2% ammoniacal liquor regulation pH value is added dropwise, and is stirred 10 minutes, place 20 minutes, nano silver-carrying titanium dioxide dispersion mixed solution is made；
（2）Chitosan 200g is weighed, is added in above-mentioned nano silver-carrying titanium dioxide mixed solution, it is 7.5 that 2% watery hydrochloric acid regulation pH value, which is added dropwise, heating water bath is to 65 DEG C, stirring 5 minutes, add deionized water that nano silver-carrying titanium dioxide-chitosan composite antibacterial solution is made to 10000ml；
4th, the silicone catheter Jing Guo surface-active-treatment is put into the nano silver-carrying titanium dioxide with heating water bath to 65 DEG C-chitosan composite antibacterial solution, soaked 3 minutes, take out airing；
5th, the silicone catheter after step 4 being handled is put into curing cage, and 170 DEG C vulcanize 5 hours, completes preparation of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone catheter surface coating.Obtain antibacterial silica gel catheter of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone catheter surface coating.
Silicone catheter through above-mentioned nano silver-carrying titanium dioxide-chitosan composite antibacterial material coating, is antibacterial silica gel catheter, and its antibacterial bacteriostatic rate is up to 92.3%.
Silicone catheter silica gel drainage tube, connecting silicone pipe are replaced, antibacterial silica gel drainage tube, antibacterial silica gel connecting tube is made.
Embodiment 3：
As shown in figure 1, a kind of antimicrobial silicon sebific duct, including silica gel tube body 1 and the nano silver-carrying titanium dioxide-chitosan composite antibacterial material layer 2 for being covered in the surface of silica gel tube body 1.
The antimicrobial silicon sebific duct is antibacterial silica gel catheter.
Nano silver-carrying titanium dioxide-chitosan the composite antibacterial material, including be made up of the raw material of following weight：Nano silver-carrying titanium dioxide 0.15, KH-550 silane couplers 0.07, chitosan 0.25.
Nano silver-carrying titanium dioxide-chitosan the composite antibacterial material silicone catheter surface coating preparation method, including：
1st, according to a conventional method silicone catheter extrusion molding；
2nd, silicone catheter surface modification treatment
（1）Silica Surface activity treatment fluid is prepared：
95% aqueous isopropanol 1000ml, 150 grams of double two or four vulcanizing agents, 100 grams of crosslinking agent UN-125F are separately added into 10kg deionized waters, is stirred and evenly mixed, it is standby；
（2）The silicone catheter newly extruded is put into after being soaked 25 seconds in the Silica Surface activity treatment fluid for be heated to 50 DEG C and taken out, airing；
3rd, nano silver-carrying titanium dioxide-chitosan composite antibacterial material mixed solution is prepared
（1）Nano silver-carrying titanium dioxide 150g is weighed, adds deionized water 1000ml, heating water bath is to 80 DEG C, stirring 5 minutes, it is 8 to add KH-550 silane couplers 50ml, 2% ammoniacal liquor regulation pH value is added dropwise, and is stirred 10 minutes, place 20 minutes, nano silver-carrying titanium dioxide dispersion mixed solution is made；
（2）Chitosan 250g is weighed, is added in above-mentioned nano silver-carrying titanium dioxide mixed solution, it is 7 that 2% watery hydrochloric acid regulation pH value, which is added dropwise, and heating water bath stirs 8 minutes to 65 DEG C, adds deionized water that nano silver-carrying titanium dioxide-chitosan composite antibacterial solution is made to 10000ml；
4th, the silicone catheter Jing Guo surface-active-treatment is put into the nano silver-carrying titanium dioxide with heating water bath to 70 DEG C-chitosan composite antibacterial solution, soaked 3 minutes, take out airing；
5th, the silicone catheter after step 4 being handled is put into curing cage, and 175 DEG C vulcanize 5 hours, completes preparation of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone catheter surface coating.Obtain antibacterial silica gel catheter of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone catheter surface coating.
Silicone catheter through above-mentioned nano silver-carrying titanium dioxide-chitosan composite antibacterial material coating, is antibacterial silica gel catheter, and its antibacterial bacteriostatic rate is up to 93.5%.
Silicone catheter silica gel drainage tube, connecting silicone pipe are replaced, antibacterial silica gel drainage tube, antibacterial silica gel connecting tube is made.
Claims (10)
1. a kind of antimicrobial silicon sebific duct, it is characterised in that including silica gel tube body and be covered in nano silver-carrying titanium dioxide-chitosan composite antibacterial material layer of the silicone tube body surface.
2. antimicrobial silicon sebific duct according to claim 1, it is characterised in that the antimicrobial silicon sebific duct is antibacterial silica gel catheter, antibacterial silica gel drainage tube or antibacterial silica gel connecting tube.
3. a kind of composite antibacterial material, it is characterised in that the composite antibacterial material is nano silver-carrying titanium dioxide-chitosan composite antibacterial material, including is made up of the raw material of following weight：Nano silver-carrying titanium dioxide 0.1-0.2, KH-550 silane coupler 0.05-0.1, chitosan 0.2-0.3.
4. composite antibacterial material according to claim 3, it is characterised in that the nano silver-carrying titanium dioxide-chitosan composite antibacterial material includes being made up of the raw material of following weight：Nano silver-carrying titanium dioxide 0.15, KH-550 silane couplers 0.07, chitosan 0.25.
5. composite antibacterial material according to claim 3, it is characterised in that the preparation method of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material mixed solution, including
（1）By weight ratio, in every 10 parts of nano silver-carryings titanium dioxide dispersion mixed solution, the 0.1-0.2 parts of titanium dioxide containing nano silver-carrying, KH-550 silane coupler 0.05-0.1 parts, chitosan 0.2-0.3 parts, remaining is deionized water；
（2）The preparation of composite dispersion mixed solution
Sodium rice is first carried silver-colored titanium dioxide to be added in appropriate amount of deionized water, heating water bath is to 75-85 DEG C, stirring 5 minutes, KH-550 silane couplers are added, 2% ammoniacal liquor, which is added dropwise, makes pH value be 8-9, stirs 10 minutes, add chitosan, 2% watery hydrochloric acid, which is added dropwise, makes pH value stir 10 minutes up to being 6-7.5, nano silver-carrying titanium dioxide-chitosan composite dispersion mixed solution is made.
6. a kind of composite antibacterial material is in the preparation method of silicone tube surface coating, it is characterised in that the composite antibacterial material is nano silver-carrying titanium dioxide-chitosan composite antibacterial material, and methods described includes：
1）, Silica Surface modification
（1）Silica Surface activity treatment fluid is prepared：
By weight ratio, in every 10 parts of Silica Surfaces activity treatment fluid, containing 1 part of 95% aqueous isopropanol, double two or four vulcanizing agent 0.1-0.2 parts, crosslinking agent UN-125F 0.08-0.15 parts, remaining is deionized water；
（2）Carry out surface modification treatment：
The silica gel being newly molded is put into after soaking the 20-30 seconds in the Silica Surface activity treatment fluid for be heated to 45-55 DEG C and taken out, airing is standby；
2）, prepare nano silver-carrying titanium dioxide-chitosan composite antibacterial material mixed solution
（1）By weight ratio, in every 10 parts of nano silver-carryings titanium dioxide dispersion mixed solution, the 0.1-0.2 parts of titanium dioxide containing nano silver-carrying, KH-550 silane coupler 0.05-0.1 parts, chitosan 0.2-0.3 parts, remaining is deionized water；
（2）The preparation of composite dispersion mixed solution
Sodium rice is first carried silver-colored titanium dioxide to be added in appropriate amount of deionized water, heating water bath is to 75-85 DEG C, stirring 5 minutes, KH-550 silane couplers are added, 2% ammoniacal liquor, which is added dropwise, makes pH value be 8-9, stirs 10 minutes, add chitosan, 2% watery hydrochloric acid, which is added dropwise, makes pH value stir 10 minutes up to being 6-7.5, nano silver-carrying titanium dioxide-chitosan composite dispersion mixed solution is made；
3）, step 1）Silica gel by surface modification treatment is put into the nano silver-carrying titanium dioxide-chitosan composite dispersion mixed solution for being heated to 65-75 DEG C, is carried out coating and is soaked 3 minutes, takes out airing；
4）, step 3）Silica gel after processing is put into curing cage, and 170-180 DEG C of temperature vulcanizes 5 hours, completes preparation of the nano silver-carrying titanium dioxide-chitosan composite antibacterial material in silicone tube surface coating.
7. composite antibacterial material according to claim 6 is in the preparation method of silicone tube surface coating, it is characterised in that step 1）Middle Silica Surface activity treatment fluid is prepared：By weight ratio, in every 10 parts of Silica Surfaces activity treatment fluid, containing 1 part of 95% aqueous isopropanol, double 0.15 part of two or four vulcanizing agents, crosslinking agent UN-125F
0.1 part, remaining is deionized water.
8. composite antibacterial material according to claim 6 is in the preparation method of silicone tube surface coating, it is characterised in that step 2）In, prepare in nano silver-carrying titanium dioxide-chitosan composite antibacterial material mixed solution,（1）By weight ratio, in every 10 parts of nano silver-carryings titanium dioxide dispersion mixed solution, 0.15 part of titanium dioxide containing nano silver-carrying, 0.07 part of KH-550 silane couplers, 0.25 part of chitosan, remaining is deionized water.
9. a kind of antimicrobial silicon sebific duct, it is characterised in that the antimicrobial silicon sebific duct is made up of the preparation method described in claim any one of 6-8.
10. application of the preparation method in antimicrobial silicon sebific duct is prepared described in claim any one of 6-8.
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| CN112021970A (en) * | 2020-06-30 | 2020-12-04 | 浙江科迅工贸有限公司 | Novel antibacterial adjustable bathroom stool |
| CN113549329A (en) * | 2021-06-30 | 2021-10-26 | 杭州三创有机硅有限公司 | Production process of color line pipe |
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| CN113549329A (en) * | 2021-06-30 | 2021-10-26 | 杭州三创有机硅有限公司 | Production process of color line pipe |
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| CN107485732B (en) | 2023-03-10 |
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