CN1074832A - Quick-acting burn medicine and its preparation - Google Patents
Quick-acting burn medicine and its preparation Download PDFInfo
- Publication number
- CN1074832A CN1074832A CN 93101400 CN93101400A CN1074832A CN 1074832 A CN1074832 A CN 1074832A CN 93101400 CN93101400 CN 93101400 CN 93101400 A CN93101400 A CN 93101400A CN 1074832 A CN1074832 A CN 1074832A
- Authority
- CN
- China
- Prior art keywords
- grams
- radix
- benzyl alcohol
- quick
- borneolum syntheticum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims abstract description 36
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 20
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 14
- 239000009286 sanguis draxonis Substances 0.000 claims abstract description 13
- 235000019445 benzyl alcohol Nutrition 0.000 claims abstract description 12
- 238000005325 percolation Methods 0.000 claims abstract description 9
- 239000000843 powder Substances 0.000 claims abstract description 6
- 238000001914 filtration Methods 0.000 claims abstract description 4
- 238000003756 stirring Methods 0.000 claims abstract description 4
- 229940079593 drug Drugs 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 8
- 235000012054 meals Nutrition 0.000 claims description 6
- 239000009806 pulsatillae Substances 0.000 claims description 5
- 238000005202 decontamination Methods 0.000 claims description 3
- 230000003588 decontaminative effect Effects 0.000 claims description 3
- 238000007598 dipping method Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000012856 packing Methods 0.000 claims description 3
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 3
- 229940098465 tincture Drugs 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 2
- 231100000241 scar Toxicity 0.000 abstract description 2
- 238000002791 soaking Methods 0.000 abstract 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 208000032544 Cicatrix Diseases 0.000 abstract 1
- 244000018716 Impatiens biflora Species 0.000 abstract 1
- 235000015912 Impatiens biflora Nutrition 0.000 abstract 1
- 241001071917 Lithospermum Species 0.000 abstract 1
- 240000004064 Poterium sanguisorba Species 0.000 abstract 1
- 235000008291 Poterium sanguisorba Nutrition 0.000 abstract 1
- 241000206469 Pulsatilla Species 0.000 abstract 1
- 244000294611 Punica granatum Species 0.000 abstract 1
- 235000014360 Punica granatum Nutrition 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 235000008282 Sanguisorba officinalis Nutrition 0.000 abstract 1
- 235000005155 Tanacetum balsamita Nutrition 0.000 abstract 1
- 240000004824 Trimezia steyermarkii Species 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 239000009136 dragon's blood Substances 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 230000037387 scars Effects 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 description 8
- 208000027418 Wounds and injury Diseases 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 230000017423 tissue regeneration Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229960003600 silver sulfadiazine Drugs 0.000 description 1
- UEJSSZHHYBHCEL-UHFFFAOYSA-N silver(1+) sulfadiazinate Chemical compound [Ag+].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 UEJSSZHHYBHCEL-UHFFFAOYSA-N 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention relates to a quick-acting burn medicine and process for preparation, wherein the main constituents are: rhubarb, angelica dahurica, lithospermum, salvia miltiorrhiza, pomegranate bark, Chinese pulsatilla root, radix sophorae flavescentis, garden burnet root, dragon's blood, borneol, garden balsam stem and benzyl alcohol. Pulverizing sanguis Draxonis and Borneolum Syntheticum into fine powder, sieving benzyl alcohol and other fine materials to remove impurities, and making into coarse powder; soaking the coarse powder with ethanol, placing into a percolation tank, soaking with ethanol, percolating, adding sanguis Draxonis and Borneolum Syntheticum and benzyl alcohol into the percolate, stirring, and filtering with multilayer gauze. The tincture is an external tincture, has quick pain relieving effect, does not leave scars or color spots, and can heal in 5-6 days generally.
Description
The present invention is quick-acting burn drug and preparation method thereof.
Now the method for treatment burn is broadly divided into two kinds of dry therapy and moist exposed therapies.
Dry therapy is that medicines such as silver sulfadiazine are directly imposed on the burn position, promotes that burn site forms a scab as early as possible.But this therapy has the advantage of bacteria growing inhibiting, but used drug price costliness, and is unfavorable for the tissue regeneration of burn site, sometimes even can increase the weight of the necrosis of tissue of burn, need stand bigger misery when the patient changes dressings.
The moist exposed therapy directly imposes on the burn position with medicines such as BURN MOISTEN UNGUENTUM.This therapy is difficult to stop antibacterial to invade owing to edema wound, organize transudate to increase, and causes traumatic infection easily, prolongs healing time, and brings inconvenience to daily life.
The objective of the invention is to design used medicine-quick-acting burn drug of a kind of treatment burn between above-mentioned two kinds of therapies and preparation method thereof.
Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Salviae Miltiorrhizae, the Pericarpium Granati of mainly consisting of of the present invention, the Radix Pulsatillae, Radix Sophorae Flavescentis, Radix Sanguisorbae, Sanguis Draxonis, Borneolum Syntheticum, Herba speranskiae tuberculatae, benzyl alcohol is made fine powder with Sanguis Draxonis and Borneolum Syntheticum, will make corase meal behind all the other the various composition sieve decontaminations outside benzyl alcohol and the various fines composition; Begin percolation after the percolation cylinder reuse alcohol dipping of packing into after corase meal soaked into ethanol, add Sanguis Draxonis in the liquid of collecting of filtering and Borneolum Syntheticum adds benzyl alcohol again, the back that stirs is with the multilamellar filtered through gauze.
The present invention is a kind of external-use tincture burns between dry therapy and the used medicine of moisture treatment, can directly impose on burn site, also burn site can be bandaged the back with the spray pattern medication.The alcohol content of finished product of the present invention is 50~70%, and medicine uniform distribution on wound surface after the medication is faster than oily class medicine to the subcutaneous tissue infiltration, can volatilize rapidly and take away the heat in affected part, reduces the heat effect that adds up, and pain relieving is fast; On wound surface, form one deck pseudomembrane after the medication, can prevent bacterial infection.
Pain relieving of the present invention is fast, pain relieving immediately after spraying; Cure back preventing from scar and mottle; Need not change dressings during treatment, patient's misery is few; Can spray across clothes, easy to use; Can be used for the treatment of the residual wound due to burn and the various wound, treat residual wound and can fully recover in general 5~6 days; When being used for the treatment of burn, preceding generally speaking II degree burn can be fully recovered in 5~6 days.
In addition, the present invention also has antibacterial and sterilization, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, promoting tissue regeneration and ulcer healing, microcirculation improvement, promotion and organizes effects such as oxygen supply.
Below the invention will be further described.
Quick-acting burn drug is mainly formed and each predominant quantity is Radix Et Rhizoma Rhei's 300~400 grams, the Radix Angelicae Dahuricae 150~250 grams, Radix Arnebiae (Radix Lithospermi) 250~350 grams, Radix Salviae Miltiorrhizae 200~300 grams, Pericarpium Granati 100~200 grams, the Radix Pulsatillae 100~200 grams, Radix Sophorae Flavescentis 100~200 grams, Radix Sanguisorbae 200~300 grams, Sanguis Draxonis 20~100 grams, Borneolum Syntheticum 20~80 grams, Herba speranskiae tuberculatae 20~80 grams, 10~15 milliliters of benzyl alcohol.
Quick-acting burn drug, each predominant quantity is the following is best Radix Et Rhizoma Rhei 350~370 grams, the Radix Angelicae Dahuricae 190~210 grams, Radix Arnebiae (Radix Lithospermi) 290~310 grams, Radix Salviae Miltiorrhizae 240~260 grams, Pericarpium Granati 140~160 grams, the Radix Pulsatillae 140~160 grams, Radix Sophorae Flavescentis 140~160 grams, Radix Sanguisorbae 250~270 grams, Sanguis Draxonis 30~50 grams, Borneolum Syntheticum 30~50 grams, Herba speranskiae tuberculatae 30~50 grams, 12 milliliters of benzyl alcohol.
The preparation method of quick-acting burn drug,
(1). Sanguis Draxonis and Borneolum Syntheticum are made fine powder, will make corase meal behind all the other the various composition sieve decontaminations outside benzyl alcohol and the various fines composition;
(2). corase meal is soaked into diel with 75% ethanol, 10000 milliliters of dippings 2~3 of percolation cylinder reuse 75% ethanol of packing into begin percolation round the clock, the percolation speed controlling is in 120~160 ml/min, collection about 9500 milliliters of the liquid of filtering, add Sanguis Draxonis and Borneolum Syntheticum after reuse 75% ethanol adjust to 12000 milliliters;
(3). add benzyl alcohol, the back multilamellar filtered through gauze that stirs, bottling.
Claims (3)
1, quick-acting burn drug is characterized in that: mainly composition and each predominant quantity are Radix Et Rhizoma Rhei's 300~400 grams, the Radix Angelicae Dahuricae 150~250 grams, Radix Arnebiae (Radix Lithospermi) 250~350 grams, Radix Salviae Miltiorrhizae 200~300 grams, Pericarpium Granati 100~200 grams, the Radix Pulsatillae 100~200 grams, Radix Sophorae Flavescentis 100~200 grams, Radix Sanguisorbae 200~300 grams, Sanguis Draxonis 20~100 grams, Borneolum Syntheticum 20~80 grams, Herba speranskiae tuberculatae 20~80 grams, 10~15 milliliters of benzyl alcohol.
2, quick-acting burn drug as claimed in claim 1 is characterized in that: mainly composition and each predominant quantity are Radix Et Rhizoma Rhei's 350~370 grams, the Radix Angelicae Dahuricae 190~210 grams, Radix Arnebiae (Radix Lithospermi) 290~310 grams, Radix Salviae Miltiorrhizae 240~260 grams, Pericarpium Granati 140~160 grams, the Radix Pulsatillae 140~160 grams, Radix Sophorae Flavescentis 140~160 grams, Radix Sanguisorbae 250~270 grams, Sanguis Draxonis 30~50 grams, Borneolum Syntheticum 30~50 grams, Herba speranskiae tuberculatae 30~50 grams, 12 milliliters of benzyl alcohol.
3, the preparation method of quick-acting burn drug is characterized in that:
(1). Sanguis Draxonis and Borneolum Syntheticum are made fine powder, will make corase meal behind all the other the various composition sieve decontaminations outside benzyl alcohol and the various fines composition;
(2). corase meal is soaked into diel with 75% ethanol, 10000 milliliters of dippings 2~3 of percolation cylinder reuse 75% ethanol of packing into begin percolation round the clock, the percolation speed controlling is in 120~160 ml/min, collection about 9500 milliliters of the liquid of filtering, add Sanguis Draxonis and Borneolum Syntheticum after reuse 75% ethanol adjust to 12000 milliliters;
(3). add benzyl alcohol, the back multilamellar filtered through gauze that stirs, bottling.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 93101400 CN1074832A (en) | 1993-02-19 | 1993-02-19 | Quick-acting burn medicine and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 93101400 CN1074832A (en) | 1993-02-19 | 1993-02-19 | Quick-acting burn medicine and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1074832A true CN1074832A (en) | 1993-08-04 |
Family
ID=4983562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 93101400 Pending CN1074832A (en) | 1993-02-19 | 1993-02-19 | Quick-acting burn medicine and its preparation |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1074832A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1056515C (en) * | 1994-04-15 | 2000-09-20 | 彭勃 | Zizhi medical cream |
CN1087948C (en) * | 1999-07-26 | 2002-07-24 | 吴永春 | Fast-acting burn and scald treating liquid |
CN1895371B (en) * | 2006-06-30 | 2010-12-29 | 天津市喆龙保健食品有限公司 | Inebriant for treating scald and burn |
CN101336992B (en) * | 2008-08-19 | 2011-12-28 | 宋俊锋 | Traditional Chinese medicine preparation for treating early burn or scald |
US8298592B2 (en) | 2005-12-05 | 2012-10-30 | Jong Hyun Nam | Hair growth stimulants adn the manufacturing method thereof |
-
1993
- 1993-02-19 CN CN 93101400 patent/CN1074832A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1056515C (en) * | 1994-04-15 | 2000-09-20 | 彭勃 | Zizhi medical cream |
CN1087948C (en) * | 1999-07-26 | 2002-07-24 | 吴永春 | Fast-acting burn and scald treating liquid |
US8298592B2 (en) | 2005-12-05 | 2012-10-30 | Jong Hyun Nam | Hair growth stimulants adn the manufacturing method thereof |
CN1895371B (en) * | 2006-06-30 | 2010-12-29 | 天津市喆龙保健食品有限公司 | Inebriant for treating scald and burn |
CN101336992B (en) * | 2008-08-19 | 2011-12-28 | 宋俊锋 | Traditional Chinese medicine preparation for treating early burn or scald |
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Legal Events
Date | Code | Title | Description |
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C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C06 | Publication | ||
PB01 | Publication | ||
C01 | Deemed withdrawal of patent application (patent law 1993) | ||
WD01 | Invention patent application deemed withdrawn after publication |