CN107468871A - 一种治疗肿瘤的中药组合物及其制备方法 - Google Patents
一种治疗肿瘤的中药组合物及其制备方法 Download PDFInfo
- Publication number
- CN107468871A CN107468871A CN201710887657.8A CN201710887657A CN107468871A CN 107468871 A CN107468871 A CN 107468871A CN 201710887657 A CN201710887657 A CN 201710887657A CN 107468871 A CN107468871 A CN 107468871A
- Authority
- CN
- China
- Prior art keywords
- parts
- root
- tumour
- chinese
- huang
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 77
- 239000003814 drug Substances 0.000 title claims abstract description 64
- 239000000203 mixture Substances 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims description 10
- 229940079593 drug Drugs 0.000 claims abstract description 24
- 239000009636 Huang Qi Substances 0.000 claims abstract description 23
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims abstract description 23
- 241000219784 Sophora Species 0.000 claims abstract description 23
- 241000219068 Actinidia Species 0.000 claims abstract description 22
- 241000282806 Rhinoceros Species 0.000 claims abstract description 22
- 240000008397 Ganoderma lucidum Species 0.000 claims abstract description 21
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims abstract description 21
- 241001248610 Ophiocordyceps sinensis Species 0.000 claims abstract description 21
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 21
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 21
- 244000233952 Polygonum bistorta Species 0.000 claims abstract description 21
- 235000014258 Polygonum bistorta Nutrition 0.000 claims abstract description 21
- 235000008434 ginseng Nutrition 0.000 claims abstract description 21
- 241000208365 Celastraceae Species 0.000 claims abstract description 20
- 241000601164 Clematis orientalis Species 0.000 claims abstract description 20
- 244000048199 Hibiscus mutabilis Species 0.000 claims abstract description 20
- 235000000336 Solanum dulcamara Nutrition 0.000 claims abstract description 20
- MBLBDJOUHNCFQT-LXGUWJNJSA-N aldehydo-N-acetyl-D-glucosamine Chemical compound CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 19
- 241000332747 Dysosma versipellis Species 0.000 claims abstract description 14
- 241000208340 Araliaceae Species 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 238000011282 treatment Methods 0.000 claims description 19
- 238000001914 filtration Methods 0.000 claims description 7
- 241000238557 Decapoda Species 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 abstract description 42
- 230000000694 effects Effects 0.000 abstract description 25
- 235000005206 Hibiscus Nutrition 0.000 abstract description 17
- 235000007185 Hibiscus lunariifolius Nutrition 0.000 abstract description 17
- 235000003973 Hibiscus mutabilis Nutrition 0.000 abstract description 17
- 244000284380 Hibiscus rosa sinensis Species 0.000 abstract description 17
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 16
- 230000001093 anti-cancer Effects 0.000 abstract description 16
- 208000026435 phlegm Diseases 0.000 abstract description 16
- 244000018716 Impatiens biflora Species 0.000 abstract description 9
- 235000015912 Impatiens biflora Nutrition 0.000 abstract description 9
- 235000005155 Tanacetum balsamita Nutrition 0.000 abstract description 9
- 239000008280 blood Substances 0.000 abstract description 8
- 210000004369 blood Anatomy 0.000 abstract description 7
- 210000004881 tumor cell Anatomy 0.000 abstract description 6
- 230000008093 supporting effect Effects 0.000 abstract description 5
- 206010003694 Atrophy Diseases 0.000 abstract description 3
- 230000037444 atrophy Effects 0.000 abstract description 3
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 20
- 230000002401 inhibitory effect Effects 0.000 description 17
- 210000004185 liver Anatomy 0.000 description 17
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 13
- 201000005202 lung cancer Diseases 0.000 description 13
- 208000020816 lung neoplasm Diseases 0.000 description 13
- 231100000614 poison Toxicity 0.000 description 13
- 201000007270 liver cancer Diseases 0.000 description 12
- 208000014018 liver neoplasm Diseases 0.000 description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 230000008961 swelling Effects 0.000 description 10
- 240000002853 Nelumbo nucifera Species 0.000 description 9
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 9
- 201000010099 disease Diseases 0.000 description 9
- 239000002574 poison Substances 0.000 description 9
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 8
- 239000000706 filtrate Substances 0.000 description 8
- 201000009030 Carcinoma Diseases 0.000 description 7
- 206010030113 Oedema Diseases 0.000 description 7
- 208000004880 Polyuria Diseases 0.000 description 7
- 230000000259 anti-tumor effect Effects 0.000 description 7
- 230000035619 diuresis Effects 0.000 description 7
- 230000036039 immunity Effects 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 7
- 208000000461 Esophageal Neoplasms Diseases 0.000 description 6
- 208000005718 Stomach Neoplasms Diseases 0.000 description 6
- 238000002512 chemotherapy Methods 0.000 description 6
- 235000009508 confectionery Nutrition 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 210000001835 viscera Anatomy 0.000 description 6
- 206010061902 Pancreatic neoplasm Diseases 0.000 description 5
- 230000034994 death Effects 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 206010017758 gastric cancer Diseases 0.000 description 5
- 230000001939 inductive effect Effects 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 201000011549 stomach cancer Diseases 0.000 description 5
- 230000001629 suppression Effects 0.000 description 5
- 206010006187 Breast cancer Diseases 0.000 description 4
- 208000026310 Breast neoplasm Diseases 0.000 description 4
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 4
- 206010010904 Convulsion Diseases 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 230000036461 convulsion Effects 0.000 description 4
- 230000002708 enhancing effect Effects 0.000 description 4
- 208000032839 leukemia Diseases 0.000 description 4
- 210000000496 pancreas Anatomy 0.000 description 4
- 238000001959 radiotherapy Methods 0.000 description 4
- 238000005728 strengthening Methods 0.000 description 4
- 206010000060 Abdominal distension Diseases 0.000 description 3
- 206010003445 Ascites Diseases 0.000 description 3
- 208000003174 Brain Neoplasms Diseases 0.000 description 3
- 208000000616 Hemoptysis Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 229930013930 alkaloid Natural products 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 208000006673 asthma Diseases 0.000 description 3
- 201000001531 bladder carcinoma Diseases 0.000 description 3
- 201000010881 cervical cancer Diseases 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 230000037213 diet Effects 0.000 description 3
- 210000003128 head Anatomy 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000023597 hemostasis Effects 0.000 description 3
- 235000008216 herbs Nutrition 0.000 description 3
- 230000001976 improved effect Effects 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 210000002429 large intestine Anatomy 0.000 description 3
- 210000005229 liver cell Anatomy 0.000 description 3
- 208000008443 pancreatic carcinoma Diseases 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- 230000007096 poisonous effect Effects 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 208000010570 urinary bladder carcinoma Diseases 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 208000005016 Intestinal Neoplasms Diseases 0.000 description 2
- ZSBXGIUJOOQZMP-UHFFFAOYSA-N Isomatrine Natural products C1CCC2CN3C(=O)CCCC3C3C2N1CCC3 ZSBXGIUJOOQZMP-UHFFFAOYSA-N 0.000 description 2
- ZSBXGIUJOOQZMP-JLNYLFASSA-N Matrine Chemical compound C1CC[C@H]2CN3C(=O)CCC[C@@H]3[C@@H]3[C@H]2N1CCC3 ZSBXGIUJOOQZMP-JLNYLFASSA-N 0.000 description 2
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 description 2
- 206010061306 Nasopharyngeal cancer Diseases 0.000 description 2
- 206010028813 Nausea Diseases 0.000 description 2
- 241001494479 Pecora Species 0.000 description 2
- 206010039491 Sarcoma Diseases 0.000 description 2
- VQQVWGVXDIPORV-UHFFFAOYSA-N Tryptanthrine Chemical compound C1=CC=C2C(=O)N3C4=CC=CC=C4C(=O)C3=NC2=C1 VQQVWGVXDIPORV-UHFFFAOYSA-N 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000003797 alkaloid derivatives Chemical class 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000002612 cardiopulmonary effect Effects 0.000 description 2
- 208000019065 cervical carcinoma Diseases 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 201000004101 esophageal cancer Diseases 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 201000002313 intestinal cancer Diseases 0.000 description 2
- 229930014456 matrine Natural products 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 201000011216 nasopharynx carcinoma Diseases 0.000 description 2
- 201000002528 pancreatic cancer Diseases 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- XVPBINOPNYFXID-JARXUMMXSA-N 85u4c366qs Chemical compound C([C@@H]1CCC[N@+]2(CCC[C@H]3[C@@H]21)[O-])N1[C@@H]3CCCC1=O XVPBINOPNYFXID-JARXUMMXSA-N 0.000 description 1
- 102100036475 Alanine aminotransferase 1 Human genes 0.000 description 1
- 108010082126 Alanine transaminase Proteins 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 241001566735 Archon Species 0.000 description 1
- 206010005949 Bone cancer Diseases 0.000 description 1
- 208000009458 Carcinoma in Situ Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 1
- GQEVCHQXWPWARL-UHFFFAOYSA-N Couroupitine A Natural products N1=CC=CC2=CC(=O)N3C4=CC=CC=C4C(=O)C3=C21 GQEVCHQXWPWARL-UHFFFAOYSA-N 0.000 description 1
- CRDNMYFJWFXOCH-BUHFOSPRSA-N Couroupitine B Natural products N\1C2=CC=CC=C2C(=O)C/1=C1/C2=CC=CC=C2NC1=O CRDNMYFJWFXOCH-BUHFOSPRSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 208000002699 Digestive System Neoplasms Diseases 0.000 description 1
- 206010061818 Disease progression Diseases 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 208000003468 Ehrlich Tumor Carcinoma Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 108020004206 Gamma-glutamyltransferase Proteins 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010019799 Hepatitis viral Diseases 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 241000521257 Hydrops Species 0.000 description 1
- 235000000177 Indigofera tinctoria Nutrition 0.000 description 1
- 102100034343 Integrase Human genes 0.000 description 1
- 206010023129 Jaundice cholestatic Diseases 0.000 description 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- 206010023825 Laryngeal cancer Diseases 0.000 description 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 1
- 206010025323 Lymphomas Diseases 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 241001529936 Murinae Species 0.000 description 1
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 description 1
- 201000005267 Obstructive Jaundice Diseases 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 229930187719 Soyasaponin Natural products 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 206010065954 Stubbornness Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 206010044684 Trismus Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 208000037842 advanced-stage tumor Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000003288 anthiarrhythmic effect Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000118 anti-neoplastic effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 238000011394 anticancer treatment Methods 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 235000013793 astaxanthin Nutrition 0.000 description 1
- 150000001514 astaxanthins Chemical class 0.000 description 1
- 150000004054 benzoquinones Chemical class 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 210000001772 blood platelet Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000005907 cancer growth Effects 0.000 description 1
- 208000025085 carcinoma of parotid gland Diseases 0.000 description 1
- 201000011603 cardia cancer Diseases 0.000 description 1
- 239000000496 cardiotonic agent Substances 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 230000001989 choleretic effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000003748 differential diagnosis Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000005750 disease progression Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 102000006640 gamma-Glutamyltransferase Human genes 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 235000020710 ginseng extract Nutrition 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 208000002672 hepatitis B Diseases 0.000 description 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 201000004933 in situ carcinoma Diseases 0.000 description 1
- 229940097275 indigo Drugs 0.000 description 1
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 1
- CRDNMYFJWFXOCH-UHFFFAOYSA-N indirubin Chemical compound N1C2=CC=CC=C2C(=O)C1=C1C2=CC=CC=C2NC1=O CRDNMYFJWFXOCH-UHFFFAOYSA-N 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 206010023841 laryngeal neoplasm Diseases 0.000 description 1
- 201000004962 larynx cancer Diseases 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 201000002364 leukopenia Diseases 0.000 description 1
- 235000021056 liquid food Nutrition 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 210000001165 lymph node Anatomy 0.000 description 1
- 208000025036 lymphosarcoma Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- -1 matrine Natural products 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 210000000865 mononuclear phagocyte system Anatomy 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 239000003176 neuroleptic agent Substances 0.000 description 1
- 230000000701 neuroleptic effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000021590 normal diet Nutrition 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 229930015582 oxymatrine Natural products 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000001830 phrenic effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001235 sensitizing effect Effects 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 150000005856 steroid saponins Chemical class 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 210000004895 subcellular structure Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 208000025093 tonsil carcinoma Diseases 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 150000008130 triterpenoid saponins Chemical class 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/612—Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8884—Arisaema, e.g. Jack in the pulpit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Nutrition Science (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Neurosurgery (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗肿瘤的中药组合物,由以下原料组成:藤梨根、半枝莲、蛇舌癀、蜀羊泉、蚤休、山豆根、青黛、犀黄、苦参、败酱根、八角莲、人参、黄芪、虫草、灵芝、虾壳、急性子、天南星、防己、威灵仙、芙蓉叶、拳参。诸药相合,既有清热解毒攻邪散结抗癌,又注重扶正抗癌,方中用药还有祛痰、软坚、散瘀,散结抗癌等作用。此方赫赫是一个在保护机体自身功能的情况下,最大限度地杀伤恶性肿瘤,萎缩肿瘤,抑制肿瘤细胞生长,减轻患者痛苦,提高生存质量,延长生存期。
Description
技术领域
本发明属于中药技术领域,具体涉及一种治疗肿瘤的中药组合物及其制备方法。
背景技术
肿瘤是一种常见病、多发病,其中恶性肿瘤是目前危害人类健康最严重的一类疾病。在欧美一些国家,恶性肿瘤的死亡率仅次于心血管系统疾病而居第二位。根据我国1992年卫生事业发展情况统计公报,城市地区居民恶性肿瘤死亡率居死因第一位,为123.92/10万,基中男性为151.08/10 万,女性为95.12/10万。农村地区居民恶性肿瘤死亡率居第死因第二位,为 101.39/10万。其中男性为125.79/10万,女性为78.85/10万。随着我国人口老龄化的进程,加之城市人口比例逐年增高,城镇工业生产迅速发展,环境污染日益严重,吸烟等不良生活习惯相当普遍,如果不采取积极的宣传教育措施,恶性肿瘤的危害性还将日益增加。
目前医学界治疗各种肿瘤、癌症包块以切除、化疗为主,配合服药,治愈率极少,同时还产生极大的副作用。中医治疗肿瘤是我国的特色,也是我国的优势。长期以来,中医药治疗肿瘤虽已取得了一些方法与经验,但目前还存在疗程不佳,治疗周期长,无法从根本上肿瘤,因此无法完全值得普遍推广。
发明内容
本发明的目的在于针对现有技术的不足,提供一种治疗肿瘤的中药组合物及其制备方法,遵循中医辩证,依据现代医学肿瘤发病机理,具有安全高效扶正抗癌,补气养血、增加食欲,增强免疫、除痰清毒化结、利尿通便,安全无毒可萎缩肿瘤,抑制肿瘤细胞生长的功效。
本发明的目的是以下述方式实现的:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根20-50份,半枝莲15-20份,蛇舌癀15-20份,蜀羊泉15-30份,蚤休3-10份,山豆根15-25份,青黛5-10份,犀黄0.5-3份,苦参20-30份,败酱根10-15份,八角莲10-20份,人参10-15份,黄芪10-20份,虫草0.5-2份,灵芝5-15份,虾壳10-15份,急性子6-10份,天南星8-12份,防己10-15份,威灵仙10-15份,芙蓉叶8-15份,拳参10-15份。
由以下重量份的原料组成:藤梨根30-40份,半枝莲17-20份,蛇舌癀17-20份,蜀羊泉20-25份,蚤休6-10份,山豆根18-22份,青黛7-10份,犀黄1.5-3份,苦参22-28份,败酱根12-15份,八角莲12-18份,人参12-15份,黄芪12-18份,虫草1-2份,灵芝8-12份,虾壳12-15份,急性子7-9份,天南星9-11份,防己12-15份,威灵仙12-15份,芙蓉叶10-15份,拳参12-15份。
由以下重量份的原料组成:藤梨根35份,半枝莲18份,蛇舌癀18份,蜀羊泉22份,蚤休6份,山豆根20份,青黛8份,犀黄2份,苦参25份,败酱根12份,八角莲15份,人参13份,黄芪15份,虫草1.5份,灵芝10份,虾壳12份,急性子8份,天南星10份,防己13份,威灵仙12份,芙蓉叶12份,拳参14份。
如上述的治疗肿瘤的中药组合物的制备方法,原料药混合均匀,加水300-500mL煎煮,过滤,滤渣再加入300-500mL水进行煎煮,过滤,合并两次滤液即可。
如上述的治疗肿瘤的中药组合物的制备方法,原料药粉碎,粒度小于80目,混合均匀后,制成散丸即可。
方中每味药的作用原理如下:
藤梨根:酸涩,凉入胃膀胱二经,清热解毒、消毒消肿、消化不良、呕吐、防肿瘤,对风湿骨痛、消化道肿瘤等有着很好的功效。藤梨根对肝脏也有不错的功效,还能提高免疫力,增强细胞免疫的功效,还能更有效的控制癌细胞的发展,对S180、U14有抑制作用,适应症食管癌,胃癌及肠癌等。
半枝莲:辛凉入心肺二经,清热解毒、利水消肿,对S180有抑制作用,适应症各类常见肿瘤。
蛇舌癀:甘淡凉,入胃大肠小肠三经。清热解毒、软坚散结,利水消肿,对U14有抑制作用,能刺激网状内皮系统增强白血球的吞嚼作用。适应症各种常见癌瘤及消化道癌瘤。
蜀羊泉:苦微寒,入肝胃二经,清热解毒、利水消肿,对S180、WK256有抑制作用,对人体肺癌有抑制作用。适应症肝癌,胃癌,肺癌,膀胱癌及子宫颈癌等。
蚤休:苦微寒小毒,入肝经,清热解毒、消肿止痛,熄风定痉,对S180、S37实体型肝癌有抑制作用。适应症消化道癌瘤,肺癌、脑肿瘤及恶性淋巴瘤。主要含甾体皂甙(蚤休甙)、酚性成分、氨基酸等,研究发现:以本品3.1mg/ml浓度对小鼠艾氏腹水瘤及鼠肝癌细胞具有抑制作用,水煎剂腹腔注射对小鼠肉瘤的抑制率为40-50%,重楼属(Paris)的8个种和变种及10 种市售商品药材对RNA癌病毒逆转录酶均有一定抑制作用。临床多用于热毒雍滞的恶性淋巴瘤、肺癌、鼻咽癌、脑肿瘤及消化系统肿瘤如胃癌、食管癌、肝癌等,常配入复方内使用。
山豆根:苦寒,入心肺大肠三经,清热解毒、消肿止痛,利咽。山豆根生物碱有实验抗癌作用,广山豆根S180、S37、S14腹水型,肉瘤以及腹水型肝癌均有抑瘤作用。适应症喉癌,食管癌、扁桃体癌,胃癌及肝癌等、主要含苦参碱、氧化苦参碱、黄酮类衍生物及酚类化合物等。
青黛:咸寒入肝肺心胃经,清热解毒,凉血泻肝散郁火。对体外白血病细胞有抑制作用,并有抗病毒作用。适应症白血病及癌性发热。由菘蓝叶制成的青黛含靛蓝,靛玉红,青黛酮,青黛素,吲哚醌,色胺酮等成分,具有抗肿瘤,保肝,破坏白血病细胞,提高机体免疫功能,抗菌等作用。
犀黄:入心经和肝经,苦甘寒,清热解毒、镇惊、祛痰开窍,对中枢神经系统有抑制作用,有抗癌解毒利胆作用,适应症常见各种癌瘤,脑瘤、肝癌、肺癌、白血病。
苦参:苦寒,入心肝胃大肠五经,清热解毒,燥湿,祛风杀虫,对S180、U14及EC有抑制作用,适应症子宫颈癌,肝癌,大肠癌及皮肤癌等。本品含苦参碱等多种生物碱,苦参新醇等,苦参苯醌,大豆皂甙等成分,具有拟菌,抗炎,抗过敏,免疫拟制,安定,祛痰,平喘,升白细胞,抗肿瘤等作用,其生物碱有扩张血管,保护急性心肌缺血,抗心律失常等作用。
败酱根:有抗肝炎病毒作用,能促进肝细胞再生,防止肝细胞变性,改善肝功能,尚有抗肿瘤作用,抗肿瘤有显著的抗肿瘤功效。对人宫颈癌细胞的抑制率为100%。电镜观察其抑瘤作用系直接的杀伤作用。对艾氏腹水癌有明显的抑制作用,促进溃疡修复的作用。
八角莲:苦,寒,有毒。清热解毒、活血散瘀消肿,抗癌,例如乳腺癌、腮腺癌、肺癌、卵巢癌、皮肤癌等。
人参:甘,微温,归肺、脾、心、肾经。大补元气,补肺脾心肾气,生津,安神益智。对小鼠艾氏腹水癌有轻度抑制作用,人参提取物治疗肿瘤抑制率为15%-48%。适应症各种常见肿瘤证见气虚或虚脱者。
黄芪:性味属甘、微温,作用于肺、脾,具有补气升阳、预防感冒、止汗、杀菌、促进伤口愈合、消除水肿等功效。有提高免疫力的功能,还有强心利尿及保护肝细胞等药理作用。近年来,国内对黄芪抗肿瘤作用的研究认为黄芪抗肿瘤作用机制有多个方面,包括增强机体免疫功能、直接抑瘤作用、促进肿瘤细胞的凋亡、抗肿瘤血管生成、对肝癌、 胃肠道肿瘤、肺癌、 鼻咽癌、 乳腺 癌等恶性肿瘤中 都有明显的抗癌作用。
冬虫夏草:肾、肺经、调节免疫系统功能免疫抵御肿瘤,清除老化、坏死的细胞组织,对外抗击病毒、细菌等微生物感染。抗肿瘤抑制、杀伤肿瘤细胞的作用。提高细胞能量、调节肝肾脏功能,增强骨髓生成血小板、红细胞和白细胞的能力。
灵芝:甘、平。益精气,养心安神,止咳平喘,滋养强壮,补虚抗癌。
虾壳:味甘;咸;性凉,不但含有大量蛋白质,还含有一些虾青素和矿物质,这些物质被人体吸收以后能提高身体免疫细胞活性,也能促时免疫细胞再生,能让身体的免疫能力明显提高,经常食用能提高身体的抗病含有大量蛋白质能力,也能延缓多种衰老症状的发生,抗氧化,抗衰老,抗炎症抗皮劳,抑制肿瘤细胞,提高免疫力。
急性子:微苦,温。有小毒。入肝,脾二经。软坚散结,活血通络,开关利窍。药敏试验对胃淋巴肉瘤细胞敏感。适应症食道癌,贲门癌及胃癌等。能破血攻坚;全草能祛风活血,消肿止痛。
天南星:辛,苦,温。有毒。归肺,肝,脾经。燥湿化痰,袪风止痉,消肿散结,止痛。鲜南星提取物对S180有抑制作用。适应症肺癌,食管癌,及子宫颈癌等。主要含三萜皂甙、安息香酸、淀粉、D-甘露醇和谷氨酸、亮氨酸等多种氨基酸。实验表明:鲜天南星(未鉴定品种)水提取液在1:8-1:32浓度时对Hela细胞有抑制作用:使细胞浓成团块,破坏正常细胞结构,其生用抗癌力强。
防己:苦、辛,寒。归肝、肾、膀胱经,祛风湿,止痛,利水消肿,适应症肾癌、膀胱癌、骨肿瘤、肺癌等。
威灵仙:祛风湿,通经络,消痰涎,散癖积,治痛风、顽痹、腰膝冷痛,脚气,疟疾,症瘕积聚,破伤风,扁桃体炎,诸骨鲠咽。
芙蓉叶:微辛凉清热解毒,凉血止血,散瘀消肿,排脓。
拳参:甘酸寒入肝胃二经,清热解毒、散瘀消肿 对S180及艾氏腹水癌有抑制作用。适应症肝癌,肠癌,膀胱癌及乳腺癌等。
癌毒是一种内生的邪毒,根于脏腑组织之中,根深蒂固,胶着难清,除早期原位癌外,单一的手术、化疗、放疗均不足以根治癌细胞,加之其正气不足,广泛侵袭,流窜的特点,越发显得其顽固难治,这是癌毒的又一个重要致病特点。
正气不足是癌症的内在依据《内经》云:“邪之所凑,其气必虚。” 恶性肿瘤是本虚标实疾患,所以用中医肿瘤配方,中药用以攻邪败毒抗癌,注重扶正抗癌中药治疗在保护机体自身功能的情况下,最大限度地杀伤肿瘤,减轻患者痛苦,提高生存质量,延长生存期。
恶性肿瘤尽管内容繁多,不同脏器的癌肿各具特征,但本质上却是有其共同的发生发展规律,探索这一规律,对提高中药防治恶性肿瘤的疗效有着深远的意义。现代许多中医临床工作者在前人认识的基础上,对恶性肿瘤的发生机制进行了研究,“癌毒-正虚”致病说已成为大家的共识。
中医药治疗癌症肿瘤的原理:
本方证是由邪热蕴郁,郁结不化,日久生毒而成肿块。恶性肿瘤与毒邪有关,古今医家有类似的认识认为引起癌肿的“毒”是一种特殊的毒邪《中藏经》说:“疽痈疮毒之所,皆五脏六腑蓄毒不流。非营卫壅塞而发也。”近人郁仁存认为:“热毒内蕴”是癌肿的一大病因。封菊秋曰:癌症常由“邪热蕴郁,郁结不化,灼烁脏腑,日久五脏瘀血浊气痰滞生毒本虚表实而成积聚癥瘕,治宜清热解毒、消肿止痛,软坚散结,利水消肿,扶正补虚。方中用藤梨根、半枝莲、蛇舌癀、蜀羊泉、蚤休、山豆根、青黛、犀黄、苦参、败酱根为君,攻邪败毒、散结抗癌,八角莲、芙蓉根、拳参为臣,清热解毒、活血散瘀、消肿抗癌、促使聚积的癌细胞消散,或促使异常的细胞转为正常细胞。化痰导浊法中医所说的痰,是指人体脏腑气血失和、津液运化失常而产生的有形之病理产物。痰在癌症形成过程中能起到促进作用,尤其是痰浊与瘀血为伍,交结为痰。肿瘤以痰论治,用天南星、犀黄、威灵仙为臣,消痰涎,散癥瘕积聚、消肿散结,防己利湿散留痰、痈肿恶结、扶正固本法恶性肿瘤患者往往都是体质虚弱,免疫功能低下,特别是经过手术、放射治疗、化学治疗后极易出现贫血、白细胞减少、食欲缺乏、恶心、呕吐等毒副作用,配方中人参、虫草、灵芝、黄芪为佐,益精气、扶正固本增免疫、补虚强体、改善贫血、促使白细胞上升。虾壳为使,含大量蛋白矿物质、抗氧化,抗衰老,抗炎症,抗皮劳,抑制肿瘤细胞,提高免疫力为。诸药相合,既有清热解毒攻邪散结抗癌,又注重扶正抗癌,方中用药还有祛痰、软坚、散瘀,散结抗癌等作用。此方赫赫是一个在保护机体自身功能的情况下,最大限度地杀伤恶性肿瘤,萎缩肿瘤,抑制肿瘤细胞生长,减轻患者痛苦,提高生存质量,延长生存期。
功效:祛痰软坚散结,攻邪败毒扶正抗癌。
主治:各种中晚期恶性肿瘤。
具体实施方式
实施例1:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根20-50份,半枝莲15-20份,蛇舌癀15-20份,蜀羊泉15-30份,蚤休3-10份,山豆根15-25份,青黛5-10份,犀黄0.5-3份,苦参20-30份,败酱根10-15份,八角莲10-20份,人参10-15份,黄芪10-20份,虫草0.5-2份,灵芝5-15份,虾壳10-15份,急性子6-10份,天南星8-12份,防己10-15份,威灵仙10-15份,芙蓉叶8-15份,拳参10-15份。
由以下重量份的原料组成:藤梨根30-40份,半枝莲17-20份,蛇舌癀17-20份,蜀羊泉20-25份,蚤休6-10份,山豆根18-22份,青黛7-10份,犀黄1.5-3份,苦参22-28份,败酱根12-15份,八角莲12-18份,人参12-15份,黄芪12-18份,虫草1-2份,灵芝8-12份,虾壳12-15份,急性子7-9份,天南星9-11份,防己12-15份,威灵仙12-15份,芙蓉叶10-15份,拳参12-15份。
由以下重量份的原料组成:藤梨根35份,半枝莲18份,蛇舌癀18份,蜀羊泉22份,蚤休6份,山豆根20份,青黛8份,犀黄2份,苦参25份,败酱根12份,八角莲15份,人参13份,黄芪15份,虫草1.5份,灵芝10份,虾壳12份,急性子8份,天南星10份,防己13份,威灵仙12份,芙蓉叶12份,拳参14份。
如上述的治疗肿瘤的中药组合物的制备方法,原料药混合均匀,加水300-500mL煎煮,过滤,滤渣再加入300-500mL水进行煎煮,过滤,合并两次滤液即可,早晚分两次服用。
如上述的治疗肿瘤的中药组合物的制备方法,原料药粉碎,粒度小于80目,混合均匀后,制成散丸即可,散丸一次6g,一日3次。
实施例2:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根20g,半枝莲15 g,蛇舌癀15 g,蜀羊泉15 g,蚤休3 g,山豆根15 g,青黛5 g,犀黄0.5 g,苦参20 g,败酱根10 g,八角莲10 g,人参10 g,黄芪10 g,虫草0.5 g,灵芝5 g,虾壳10 g,急性子6 g,天南星8 g,防己10 g,威灵仙10 g,芙蓉叶8 g,拳参10 g。
原料药混合均匀,加水300mL煎煮,过滤,滤渣再加入300mL水进行煎煮,过滤,合并两次滤液即可,早晚分两次服用。
实施例3:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根25g,半枝莲16 g,蛇舌癀16 g,蜀羊泉18 g,蚤休5 g,山豆根17 g,青黛6 g,犀黄1 g,苦参22 g,败酱根11 g,八角莲12 g,人参11 g,黄芪12g,虫草0.8 g,灵芝7 g,虾壳11 g,急性子7 g,天南星9 g,防己11g,威灵仙11 g,芙蓉叶9 g,拳参11 g。
原料药混合均匀,加水300mL煎煮,过滤,滤渣再加入400mL水进行煎煮,过滤,合并两次滤液即可,早晚分两次服用。
实施例4:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根30g,半枝莲17 g,蛇舌癀17 g,蜀羊泉20 g,蚤休6 g,山豆根19 g,青黛7 g,犀黄1.5 g,苦参24 g,败酱根12 g,八角莲14 g,人参12 g,黄芪14g,虫草1 g,灵芝9 g,虾壳12 g,急性子8 g,天南星10 g,防己12 g,威灵仙12 g,芙蓉叶10 g,拳参12 g。
原料药混合均匀,加水300mL煎煮,过滤,滤渣再加入500mL水进行煎煮,过滤,合并两次滤液即可,早晚分两次服用。
实施例5:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根35g,半枝莲18 g,蛇舌癀18 g,蜀羊泉24 g,蚤休8 g,山豆根21 g,青黛8 g,犀黄2 g,苦参26 g,败酱根13 g,八角莲16 g,人参13 g,黄芪16g,虫草1.2 g,灵芝11 g,虾壳13 g,急性子9 g,天南星10.5 g,防己13 g,威灵仙13 g,芙蓉叶12 g,拳参13 g。
原料药混合均匀,加水400mL煎煮,过滤,滤渣再加入500mL水进行煎煮,过滤,合并两次滤液即可,早晚分两次服用。
实施例6:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根40g,半枝莲19 g,蛇舌癀19 g,蜀羊泉28 g,蚤休9 g,山豆根23 g,青黛9 g,犀黄2.5 g,苦参28 g,败酱根14 g,八角莲18 g,人参14 g,黄芪18g,虫草1.6 g,灵芝13 g,虾壳14 g,急性子10 g,天南星11 g,防己14 g,威灵仙14 g,芙蓉叶13 g,拳参14 g。
原料药混合均匀,加水500mL煎煮,过滤,滤渣再加入500mL水进行煎煮,过滤,合并两次滤液即可,早晚分两次服用。
实施例7:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根50g,半枝莲20 g,蛇舌癀20 g,蜀羊泉30 g,蚤休10 g,山豆根25 g,青黛10 g,犀黄3 g,苦参30 g,败酱根15 g,八角莲20 g,人参15 g,黄芪20g,虫草2 g,灵芝15 g,虾壳15 g,急性子6 g,天南星12 g,防己15 g,威灵仙15 g,芙蓉叶15 g,拳参15 g。
原料药混合均匀,加水500mL煎煮,过滤,滤渣再加入400mL水进行煎煮,过滤,合并两次滤液即可,早晚分两次服用。
实施例8:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根30g,半枝莲17g,蛇舌癀17g,蜀羊泉20g,蚤休6g,山豆根18g,青黛7g,犀黄1.5g,苦参22g,败酱根12g,八角莲12g,人参12g,黄芪12g,虫草1g,灵芝8g,虾壳12g,急性子7g,天南星9g,防己12g,威灵仙12g,芙蓉叶10g,拳参12g。
原料药粉碎,粒度小于80目,混合均匀后,制成散丸即可,散丸每服6g,一日两次。
实施例9:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根40 g,半枝莲20 g,蛇舌癀20 g,蜀羊泉25 g,蚤休10 g,山豆根22 g,青黛10 g,犀黄3 g,苦参28 g,败酱根15 g,八角莲18 g,人参15 g,黄芪18g,虫草2 g,灵芝12 g,虾壳15 g,急性子9 g,天南星11 g,防己15 g,威灵仙15 g,芙蓉叶15 g,拳参15 g。
原料药粉碎,粒度小于80目,混合均匀后,制成散丸即可,散丸每服6g,一日两次。
实施例10:
一种治疗肿瘤的中药组合物,由以下重量份的原料组成:藤梨根35g,半枝莲18g,蛇舌癀18g,蜀羊泉22g,蚤休6g,山豆根20g,青黛8g,犀黄2g,苦参25 g,败酱根12g,八角莲15 g,人参13 g,黄芪15g,虫草1.5 g,灵芝10 g,虾壳12 g,急性子8 g,天南星10 g,防己13 g,威灵仙12 g,芙蓉叶12 g,拳参14 g。
原料药粉碎,粒度小于80目,混合均匀后,制成散丸即可,散丸每服6g,一日两次。
一般资料:选择2010年6月至2012年5月门诊收治的60例癌症患者作为本次研究对象,其中男32例,女28例,患者年龄在46至85之间,平均年龄在61.3岁,其中6例肺癌,10例食道癌,6例乳腺癌,11例宫颈癌,12例胃癌,15例肝癌,患者用药时间在15至165天,平均用药时间在72天,60例癌患者病情得到很大的改善,显效42例,有效17例,无效1例总有效率98.3%,结论:中药治疗癌症可代替手术,不用放疗,化疗,防治了过度化疗导致正气虚级死亡,减轻了患者痛苦,改善病情,提高患者生命质量,帮助患者尽快恢复健康,预防癌症有效率100%,对早期癌症的根治率100%,中、晚期癌下的治愈率分别为98%、70%以上,治愈率高,无毒副作用。
典型病例:
病例一:肝癌患者
李某,男,52岁农民,常年在外打工,3年前有过病毒性肝炎,平素体质一般,2010年8月出现纳差,腹胀,自12月开始出现晨起咳血,不定时隐痛,检查所示:谷丙转氨酶57,谷草转氨酶32,碱性磷酸酶165,谷氨酰转肽酶95,白球蛋白比15,直接胆红素10·3。乙肝5项1、5阳性。其他基本正常,医院初诊肝癌。
患者于12月份前来就诊,遂服上述中药肿瘤汤剂,15天之后,患者饮食好转,腹胀减轻,大便次数较前减少,一天2-3次。嘱患者按时服药,家属密切观察患者饮食、大小便及腹胀情况。一月后检查肝脏无轻度缩小,右肝斜径为118mm,肝形态失常,表面凹凸不平,呈锯齿状,内光点分布不均匀,呈短线状光带,肝未见明显占位病变,肝内血管显示欠清晰,肝静脉变细,走行迂曲,2011年2月16日患者的检查资料显示已经基本正常,身体状况良好,有效率达95%。嘱患者继续治疗定期检查。
病例二:食道癌患者
徐某,男,70岁,河南省安阳市人,
病情诊断:晚期食道食管癌,食管双源癌纵膈淋巴结转移后放疗30次,2015年12月6日到肿瘤医院初诊时患者精神一般,面色萎黄,消瘦,体重94斤,吞咽不畅,声音嘶哑严重,以流食为主,几乎不能说话,用中医肿瘤配方服药30天后,2016年1月8日患者复诊,患者不适症状明显改善,精神、体力明显好转,声音洪亮,吞咽通畅,体重增加10斤,跟以前判若两人。
病例三:晚期肺癌患者
牛某,男,58岁,林州市姚村定交厂工人;
病情诊断:晚期肺癌;
临床症状:咳嗽,胸痛,咳血,气急,消瘦,乏力;
治疗情况:经过市医院治疗32天,疗效欠佳,经化疗后病人消瘦明显,恶心,不能进食病情恶化,前来我门诊用中药肿瘤方治疗,每日一付,日服二次。
临床效果:服用15天后明显见效,咳嗽,咳血,胸痛,气喘症状消失,能正常饮食,精神大振,脸色开始红润,服用二个月后到市医院检查肿块明显缩小60%左右,服用半年时间,再次检查,肺癌肿块全部消失,恢复正常。
病例四:胰腺癌患者
王某,男,70岁,河南省新乡市退休工人;
病情诊断:晚期胰腺癌,2012年6月22日在新乡市医院诊断为:1、胰头癌并阻塞性黄胆。2、胆囊积液。2012年8月开始根据我门诊中医肿瘤配方对症设计治疗方案服药,半个疗程后,饮食、体力、精神见好。继续用药,原来皮肤黄、尿黄、纳差、恶心、乏力等症状消失。除轻度咳嗽外,余无不适。三个月后复查B超显示块状逐渐缩小;9月7日服药前B超显示胰头占位63×35毫米,10月14日复查缩小为25毫米,12月10日为20毫米(为胰头正常大小)。
从以上可以看出,中医虽然不是唯一治疗胰腺癌的方法,但是中药治疗恶性肿瘤,癌症方面有着独特的优势。中医中药能抑制胰腺癌细胞增殖,延长患者生存期。胰腺癌之所以病情进展如此之快,主要是由于癌细胞增殖速度远远高于正常细胞。中药能抑制胰腺癌细胞增殖,使癌细胞的生长受抑制,并能使部分癌细胞形态及亚细胞结构向正常方向逆转,从而延缓病情的进展,减少胰腺癌转移,延长患者生存期。
以上所述的仅是本发明的优选实施方式,应当指出,对于本领域的技术人员来说,在不脱离本发明整体构思前提下,还可以作出若干改变和改进,这些也应该视为本发明的保护范围。
Claims (5)
1.一种治疗肿瘤的中药组合物,其特征在于:由以下重量份的原料组成:藤梨根20-50份,半枝莲15-20份,蛇舌癀15-20份,蜀羊泉15-30份,蚤休3-10份,山豆根15-25份,青黛5-10份,犀黄0.5-3份,苦参20-30份,败酱根10-15份,八角莲10-20份,人参10-15份,黄芪10-20份,虫草0.5-2份,灵芝5-15份,虾壳10-15份,急性子6-10份,天南星8-12份,防己10-15份,威灵仙10-15份,芙蓉叶8-15份,拳参10-15份。
2.根据权利要求1所述的治疗肿瘤的中药组合物,其特征在于:由以下重量份的原料组成:藤梨根30-40份,半枝莲17-20份,蛇舌癀17-20份,蜀羊泉20-25份,蚤休6-10份,山豆根18-22份,青黛7-10份,犀黄1.5-3份,苦参22-28份,败酱根12-15份,八角莲12-18份,人参12-15份,黄芪12-28份,虫草1-2份,灵芝8-12份,虾壳12-15份,急性子7-9份,天南星9-11份,防己12-15份,威灵仙12-15份,芙蓉叶10-15份,拳参12-15份。
3.根据权利要求1所述的治疗肿瘤的中药组合物,其特征在于:由以下重量份的原料组成:藤梨根35份,半枝莲18份,蛇舌癀18份,蜀羊泉22份,蚤休6份,山豆根20份,青黛8份,犀黄2份,苦参25份,败酱根12份,八角莲15份,人参13份,黄芪15份,虫草1.5份,灵芝10份,虾壳12份,急性子8份,天南星10份,防己13份,威灵仙12份,芙蓉叶12份,拳参14份。
4.如权利要求1-3任一所述的治疗肿瘤的中药组合物的制备方法,其特征在于:原料药混合均匀,加水300-500mL煎煮,过滤,滤渣再加入300-500mL水进行煎煮,过滤,合并两次滤液即可。
5.如权利要求1-3任一所述的治疗肿瘤的中药组合物的制备方法,其特征在于:原料药粉碎,粒度小于80目,混合均匀后,制成散丸即可。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710887657.8A CN107468871A (zh) | 2017-09-27 | 2017-09-27 | 一种治疗肿瘤的中药组合物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710887657.8A CN107468871A (zh) | 2017-09-27 | 2017-09-27 | 一种治疗肿瘤的中药组合物及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107468871A true CN107468871A (zh) | 2017-12-15 |
Family
ID=60587022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710887657.8A Pending CN107468871A (zh) | 2017-09-27 | 2017-09-27 | 一种治疗肿瘤的中药组合物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107468871A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108042738A (zh) * | 2018-01-18 | 2018-05-18 | 孙桂霞 | 一种治疗妇科肿瘤的中药及其制备工艺 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101953975A (zh) * | 2010-09-30 | 2011-01-26 | 倪海清 | 肿瘤内服中草药片剂及制备方法 |
CN104666889A (zh) * | 2013-12-02 | 2015-06-03 | 陕西康乐中医药养生研究院 | 一种抗肿瘤的中药 |
US20160000856A1 (en) * | 2014-07-02 | 2016-01-07 | Hsiu-Hsien Tsai | Composition for preventing cancer and treating cancer and intensifying the effects of other anticancer drugs |
-
2017
- 2017-09-27 CN CN201710887657.8A patent/CN107468871A/zh active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101953975A (zh) * | 2010-09-30 | 2011-01-26 | 倪海清 | 肿瘤内服中草药片剂及制备方法 |
CN104666889A (zh) * | 2013-12-02 | 2015-06-03 | 陕西康乐中医药养生研究院 | 一种抗肿瘤的中药 |
US20160000856A1 (en) * | 2014-07-02 | 2016-01-07 | Hsiu-Hsien Tsai | Composition for preventing cancer and treating cancer and intensifying the effects of other anticancer drugs |
Non-Patent Citations (4)
Title |
---|
杨德兴: "恶性肿瘤治验三则", 《现代中西医结合杂志》 * |
梅全喜: "《广东地产药材研究》", 31 May 2011, 广东科技出版社 * |
汪振诚,陈永刚,刘子贻,沈奇桂,朱寿民: "虾壳红色素的抗氧化和抗肿瘤作用", 《东海海洋》 * |
赵建成等: "《肿瘤方剂大辞典》", 30 April 2009, 中医古籍出版社 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108042738A (zh) * | 2018-01-18 | 2018-05-18 | 孙桂霞 | 一种治疗妇科肿瘤的中药及其制备工艺 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2022143466A1 (zh) | 一种预防癌症药食同源植物中药组合物 | |
CN108186899A (zh) | 一种治疗肿瘤的中药组合物及其制备方法与应用 | |
CN107468871A (zh) | 一种治疗肿瘤的中药组合物及其制备方法 | |
CN111012892A (zh) | 一种治疗寒痰咳嗽的中药制剂 | |
CN106038965A (zh) | 一种治疗喉咙病症的中药组合物 | |
CN104161926A (zh) | 一种治疗食管癌的内服药物及其制备方法 | |
CN102886016B (zh) | 治疗胆囊息肉的中药制剂 | |
CN104998137A (zh) | 一种治疗肺病的中药组合物 | |
CN109481609A (zh) | 一种用于治疗痰瘀互结证肺癌的中药组合物及制备方法 | |
CN104740535A (zh) | 一种治疗直肠癌的药物栓剂 | |
CN104367702A (zh) | 治疗肿瘤的中药组合物 | |
CN105535716A (zh) | 一种治疗直、结肠癌的内服中药 | |
CN103520341A (zh) | 一种治疗食道癌的中药组方 | |
CN106110285B (zh) | 一种用于治疗上呼吸道及食管道疾病的中药组合物及其制剂和应用 | |
CN104474161A (zh) | 治疗食管癌的破瘀散及制备方法 | |
CN1457805A (zh) | 一种治疗食道癌的中药制剂 | |
CN1061876C (zh) | 鼻咽癌散 | |
CN104398627A (zh) | 食管癌以毒攻毒药剂及制备方法 | |
CN104688952A (zh) | 一种治疗膀胱湿热型膀胱癌的中药组合物及其制备方法 | |
CN104491264A (zh) | 治疗食道癌的清热解毒剂及制备方法 | |
CN115607646A (zh) | 一种治疗复发性口腔溃疡和慢性咽喉炎的组合物及制备法 | |
CN105521174A (zh) | 一种治疗结肠黑变病的中药 | |
CN104491263A (zh) | 食道癌活血化瘀药剂及制备方法 | |
CN107982381A (zh) | 一种治疗食道癌的中药制剂及制备方法 | |
CN108283666A (zh) | 一种抗癌中药组合物、制剂及其应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171215 |
|
RJ01 | Rejection of invention patent application after publication |