CN107441020A - The postoperative Precerving liquid of tooth-implanting and the postoperative maintenance method of tooth-implanting - Google Patents

The postoperative Precerving liquid of tooth-implanting and the postoperative maintenance method of tooth-implanting Download PDF

Info

Publication number
CN107441020A
CN107441020A CN201710692939.2A CN201710692939A CN107441020A CN 107441020 A CN107441020 A CN 107441020A CN 201710692939 A CN201710692939 A CN 201710692939A CN 107441020 A CN107441020 A CN 107441020A
Authority
CN
China
Prior art keywords
parts
chinese medicine
tooth
juice
postoperative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201710692939.2A
Other languages
Chinese (zh)
Other versions
CN107441020B (en
Inventor
覃青
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan United Tong Tang Oral Co Ltd
Original Assignee
Wuhan United Tong Tang Oral Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan United Tong Tang Oral Co Ltd filed Critical Wuhan United Tong Tang Oral Co Ltd
Priority to CN201710692939.2A priority Critical patent/CN107441020B/en
Publication of CN107441020A publication Critical patent/CN107441020A/en
Application granted granted Critical
Publication of CN107441020B publication Critical patent/CN107441020B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/86Violaceae (Violet family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Birds (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Dermatology (AREA)
  • Animal Husbandry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of postoperative Precerving liquid of tooth-implanting and the postoperative maintenance method of tooth-implanting, the postoperative Precerving liquid of tooth-implanting includes Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and honey.The postoperative Precerving liquid of tooth-implanting of the present invention has the function that anti-inflammation; it can eliminate or slow down the symptoms such as patient occurs after tooth-implanting discomfort, bleeding, pain, kill oral cavity bacterium, be advantageous to the reparation and regeneration of tissue; the surface of a wound is protected, strengthens human immunological competence.

Description

The postoperative Precerving liquid of tooth-implanting and the postoperative maintenance method of tooth-implanting
Technical field
The invention belongs to oral health technical field, and in particular to a kind of postoperative Precerving liquid of tooth-implanting and the postoperative guarantor of tooth-implanting The method of supporting.
Background technology
Hemodia, decayed tooth, the old odontoseisis of people, come off, tooth swelling and pain turn into and endanger the formidable enemy of human health, it is directly affected The normal life and work of the mankind, larger pain is brought to patient.Tooth-implanting is because with stability, security, longevity in recent years Order the characteristics of long and enjoy patient to favor.Tooth-implanting may fall off when will not be at table or speak as normal activity artificial tooth and make Into the danger for blocking tracheae or esophagus.In addition, artificial tooth root is rooted in alveolar bone, to the functional sexual stimulus of alveolar bone, can protect Alveolus bone structure is protected, avoids its atrophy.The tooth of health can be fully retained simultaneously, it is not necessary to grind off the tooth of neighbouring health. Top dentures are fixed by the fixing device on foundation pile, have good maintenance and stabilization to increase comfortably by implant denture Sense, there is good masticatory force.Implant tooth can have the very long life-span.It is aesthetic in appearance in addition, it is general as natural teeth, speak When facial expression as original the same naturally, increasing your self-confidence.
But local redness occurs in tooth-implanting postoperative wound, bleeding, even complication occurs when serious.Therefore, plant The postoperative maintenance of tooth and nursing are particularly important.The patent of invention of Application No. 201610637772.5, which discloses, belongs to oral health The preparation method of hypo-allergenic combination medicament during one tooth-implanting of preparation technical field.The combination medicament includes treatment tooth The material of allergy, material, pH value regulator, stabilizer, flavoring agent and the deionized water for reducing dentinal sensitivity pain;By the group Close medicament to be directly applied to dental surface or be applied to dental surface using denture fixing device, you can mitigate hemodia symptom immediately and by allergy Caused by pain.But patent does not disclose the postoperative Precerving liquid of tooth-implanting and the postoperative maintenance method of tooth-implanting at present.
The content of the invention
It is that tooth-implanting is postoperative for one of above shortcomings, the technical problems to be solved by the invention in the prior art Precerving liquid and the postoperative maintenance method of tooth-implanting.
The present invention seeks to what is be achieved through the following technical solutions:
The present invention provides a kind of postoperative Precerving liquid of tooth-implanting, including Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and honeybee Honey.
The present invention provides a kind of postoperative Precerving liquid of tooth-implanting, is prepared by the raw material of following weight parts:Chinese medicine extract 50-60 parts, asparagus juice 15-20 parts, zinc sulfate 1-3 parts, sodium salt 3-5 parts and honey 3-5 parts.
The present invention provides a kind of postoperative Precerving liquid of tooth-implanting, and the preparation method of the postoperative Precerving liquid of tooth-implanting is including following Step:
(1) Chinese medicine material of each parts by weight is weighed by formula:Chinese violet 3-5 parts, lampwick 1-3 parts, lalang grass rhizome 5-10 parts, reed Root 15-20 parts, honeysuckle 6-10 parts, flea stop 1-3 parts, radix glycyrrhizae 3-5 parts;
(2) Chinese medicine material is crushed respectively, crosses 20-30 mesh sieves, with 300-500 revs/min of 10-20 points of rotating speed stirring Clock, obtain Chinese medicine mixed powder;
(3) by Chinese medicine mixed powder and distilled water with solid-to-liquid ratio 1:(50-80) (g/mL) is well mixed, in infrared power 150- 200W, irradiation distance 2-4cm process conditions under infrared processing 5-10 minutes, it is using 300-400 mesh filter-cloth filterings, filtrate is dense Concentration 0.6-0.8g/mL decoction is reduced to, is cooled to room temperature, decoction is centrifuged into 10-20 with 4000-5000 revs/min of rotating speed Minute, supernatant is taken, obtains Chinese medicine extract;
(4) Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and the honey of each parts by weight are weighed, is added into Chinese medicine extract Enter asparagus juice, zinc sulfate, sodium salt and honey, 20-40 minutes are stirred with 300-500 revs/min of rotating speed, obtain mixed liquor;
(5) by mixed liquor sterilization treatment after 4-10 DEG C of preservation.
The present invention provides a kind of postoperative Precerving liquid of tooth-implanting, and the preparation method of the postoperative Precerving liquid of tooth-implanting is including following Step:
(1) raw material of each parts by weight is weighed by formula:Chinese violet 3-5 parts, lampwick 1-3 parts, lalang grass rhizome 5-10 parts, reed rhizome 15-20 parts, honeysuckle 6-10 parts, flea stop 1-3 parts, radix glycyrrhizae 3-5 parts;
(2) Chinese medicine material is crushed respectively, crosses 20-30 mesh sieves, with 300-500 revs/min of 10-20 points of rotating speed stirring Clock, obtain Chinese medicine mixed powder;
(3) the pectin enzyme aqueous solution of 3-5 times of Chinese medicine mixed powder weight is added into Chinese medicine mixed powder, the pectase is water-soluble The concentration of pectase is 0.1-0.2mg/mL in liquid, in pH 6-7,25-35 DEG C of temperature, the condition of 100-200 revs/min of rotating speed Lower reaction 2-3 minutes, reaction solution is used into 200-300 mesh filter-cloth filterings, collects solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and distilled water with solid-to-liquid ratio 1:(50-80) (g/mL) is well mixed, in infrared power 150-200W, irradiation distance 2-4cm process conditions under infrared processing 5-10 minutes, using 300-400 mesh filter-cloth filterings, will filter Liquid is concentrated into concentration 0.6-0.8g/mL decoction, is cooled to room temperature, and decoction is centrifuged with 4000-5000 revs/min of rotating speed 10-20 minutes, supernatant is taken, obtain Chinese medicine extract;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and the honey of each parts by weight are weighed, is added into Chinese medicine extract Enter asparagus juice, zinc sulfate, sodium salt and honey, 20-40 minutes are stirred with 300-500 revs/min of rotating speed, obtain mixed liquor;
(6) by mixed liquor sterilization treatment after 4-10 DEG C of preservation.
The present invention provides a kind of postoperative Precerving liquid of tooth-implanting, and the preparation method of the postoperative Precerving liquid of tooth-implanting is including following Step:
(1) raw material of each parts by weight is weighed by formula:Chinese violet 3-5 parts, lampwick 1-3 parts, lalang grass rhizome 5-10 parts, reed rhizome 15-20 parts, honeysuckle 6-10 parts, flea stop 1-3 parts, radix glycyrrhizae 3-5 parts;
(2) Chinese medicine material is crushed respectively, crosses 20-30 mesh sieves, with 300-500 revs/min of 10-20 points of rotating speed stirring Clock, obtain Chinese medicine mixed powder;
(3) the pectin enzyme aqueous solution of 3-5 times of Chinese medicine mixed powder weight is added into Chinese medicine mixed powder, the pectase is water-soluble The concentration of pectase is 0.1-0.2mg/mL in liquid, in pH 6-7,25-35 DEG C of temperature, the condition of 100-200 revs/min of rotating speed Lower reaction 2-3 minutes, reaction solution is used into 200-300 mesh filter-cloth filterings, collects solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and the polyalkylene glycol monoalkyl ether aqueous solution with solid-to-liquid ratio 1:(50-80) (g/mL) is mixed Close uniformly, the mass fraction of polyalkylene glycol monoalkyl ether is 2.5-5% wherein in the polyalkylene glycol monoalkyl ether aqueous solution, in infrared Power 150-200W, irradiation distance 2-4cm process conditions under infrared processing 5-10 minutes, using 300-400 mesh filter-cloth filterings, Concentrate the filtrate to concentration 0.6-0.8g/mL decoction, be cooled to room temperature, by decoction with 4000-5000 revs/min of rotating speed from Heart 10-20 minutes, supernatant is taken, obtains Chinese medicine extract;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and the honey of each parts by weight are weighed, is added into Chinese medicine extract Enter asparagus juice, zinc sulfate, sodium salt and honey, 20-40 minutes are stirred with 300-500 revs/min of rotating speed, obtain mixed liquor;
(6) by mixed liquor sterilization treatment after 4-10 DEG C of preservation.
Heretofore described sodium salt is sodium chloride and/or sodium taurodeoxycholate.
Preferably, the sodium salt is the mixture of sodium chloride and sodium taurodeoxycholate, wherein the sodium chloride and ox sulphur The weight ratio of NaTDC is (1.5-2.5):1.
As the preferable technical scheme of the present invention, the asparagus juice is aloe juice, the aloe juice Preparation process be:Aloe leaf is cut along aloe blade root from the middle part of aloe with pocket knife, is rinsed with the water of flowing dry Only, surface moisture is dried;In aloe leaf input juice extractor after cleaning up, stirred with 1800-2000 revs/min of rotating speed 2-3 minutes are mixed, using the filter-cloth filtering of 200-300 mesh, obtain juice;By juice be put in centrifuge with 8000-10000 turn/ 10-15 minutes are centrifuged under the rotating speed of minute, supernatant is taken, produces.
As another preferable technical scheme of the present invention, the asparagus juice is Aloe gel juice, the aloe gel The preparation process of juice is:Aloe leaf is cut along aloe blade root from the middle part of aloe with pocket knife, is rinsed with the water of flowing Totally, surface moisture is dried;Aloe leaf after cleaning up is cut off into outer skin with parer, obtains gel meat;Will be solidifying In glue meat input juice extractor, 2-3 minutes are stirred with 1800-2000 revs/min of rotating speed, using the filter-cloth filtering of 200-300 mesh, Obtain juice;Juice is put in centrifuge to centrifuge 10-15 minutes under 8000-10000 revs/min of rotating speed, takes supernatant, Produce.
Preferably, aloe gel meat is impregnated in the mass fraction 0.05-0.1% mannosan aqueous solution before squeezing the juice The 10-20 seconds, take out, drain.
The present invention also provides a kind of tooth-implanting postoperative maintenance method, is gargled using any of the above-described kind of postoperative Precerving liquid of tooth-implanting Mouthful, daily 2-3 times, each dosage 10-15mL, containing being told totally after gargling 2-3 minutes, it is used continuously 2-3 weeks.
The postoperative Precerving liquid of tooth-implanting of the present invention has the function that anti-inflammation, can eliminate or slow down tooth-implanting future trouble Discomfort that person occurs, bleeding, the symptom such as pain, kill oral cavity bacterium, are advantageous to the reparation and regeneration of tissue, protect the surface of a wound, Strengthen human immunological competence.
Embodiment
Each raw material and introduction of apparatus in embodiment:
Chinese violet, Classification system:Viola yedoensis Makino.Taste bitter, acrid, cold.The thoughts of returning home, lung channel.With clear Thermal detoxification, cool blood detumescence, the effect of clearing heat and promoting diuresis.It is specific using the source bioengineering Co., Ltd of Anhui hundred million provide pale reddish brownly Fourth.
Lampwick, it is rush family plant rush Juncus effusus L. stem marrow.Cold nature is sweet, light.The thoughts of returning home, Lung, small intestinl channel.Clearing heart fire, inducing diuresis for treating strangurtia.The specific lampwick provided using the source bioengineering Co., Ltd of Anhui hundred million.
Lalang grass rhizome, it is Imperata cylindrica (Linn.) Beauv. rhizome.Sweet-bitter flavor, it is cold in nature, it is nontoxic.Enter lung Through, stomach, small intestinl channel.Cooling blood and hemostasis, it is clearing heat and detoxicating.The specific thatch provided using Bozhou City medicine company sale Co., Ltd of one mind Root.
Reed rhizome, Classification system:Rhizoma Phragmitis.It is sweet, it is cold in nature.Channel tropism:Return lung warp, stomach.Clearing heat and promoting fluid, Relieving restlessness, preventing or arresting vomiting, diuresis.For pyreticosis polydipsia, gastropyretic vomiting, cough with lung heat, lung carbuncle pyemesis, puckery pain of heat gonorrhea.Specifically use Anguo The reed rhizome that Lin Shi medicinal materials Co., Ltd of city provides.
Honeysuckle, Classification system:Lonicera Japonica.It is sweet, slight bitter, delicate fragrance.Property it is pungent, tremble with fear.Return lung, stomach, the heart, Large intestine channel.Can dispelling wind-heat, also kind removing summer-heat blood poison.The specific gold and silver provided using Anguo City Lin Shi medicinal materials Co., Ltd Flower.
Flea stops, Classification system:Paris polyphylla Smith..Toil, tremble with fear, it is poisonous.Enter the heart, lung channel.Heat-clearing solution Poison, antiasthmatic-antitussive, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.The specific flea provided using the bright sale of the medicinal material in the rain Co., Ltd in Bozhou is stopped.
Radix glycyrrhizae, Classification system:Glycyrrhiza uralensis Fisch..Sweet sweet tea, it is mild-natured and.Enter the heart, spleen, lung, Stomach four passes through.It is raw with cooler, can purging intense heat and detonicating, relieving spasm to stop pain;Process and use partial temperature, exterior cold, tonifying middle-Jiao and Qi can be dissipated.In addition, radix glycyrrhizae is also kind In mediation property of medicine, the poison of hundred medicines of solution.The specific radix glycyrrhizae that bold and unconstrained Chinese medicine sale Co., Ltd offer is provided using Bozhou City.
Aloe, the specific aloe barbadensis Miller provided using Putian City Hanjiang District Lv He agricultural developments Co., Ltd.
Honey, the specific osmanthus honey provided using Shanghai Yi Nuo Food Co., Ltd.
Zinc sulfate, No. CAS:7733-02-0, it is specific using the medicinal of the big magnificent great achievement medication chemistry Co., Ltd offer in Wuhan Level zinc sulfate.
Sodium chloride, No. CAS:7647-14-5, the specific pharmaceutical grade chlorine that the offer of metachemistry Science and Technology Ltd. is provided using Shanghai Change sodium.
Polyalkylene glycol monoalkyl ether, No. CAS:9043-30-5, specifically carried using Nanjing Kang Manlin chemical industry Industrial Co., Ltd. The pharmaceutical grade polyalkylene glycol monoalkyl ether of confession.
Sodium taurodeoxycholate, No. CAS:1180-95-6, specifically carried using Hefei Bo Mei biotechnologies Co., Ltd The pharmaceutical grade sodium taurodeoxycholate of confession.
Mannosan, No. CAS:51395-96-1, the specific food-grade using the offer of Shanghai Meng Jiu Industrial Co., Ltd.s are sweet Reveal glycan.
Pectase, No. CAS:9032-75-1, the specific enzyme activity that the offer of Shanghai Yue Teng Bioisystech Co., Ltd be provided for 30000U/g pectase.
Juice extractor, the specific model YZ28A provided using Guangdong Heng Lian food machinerys factory juice extractor.
Centrifuge, the specific model TGL-16C provided using Anting Scientific Instrument Factory, Shanghai high speed tabletop centrifuge.
Infrared radiation device, the specific model R125's provided using Haining City Yue Hai Lighting Electric Appliance Co., Ltd is infrared Line bulb.
Embodiment 1
The postoperative Precerving liquid of tooth-implanting, is formulated and is:The parts by weight of Chinese medicine extract 60, the parts by weight of asparagus juice 20, the weight of zinc sulfate 1 Part, the parts by weight of sodium chloride 3 and the parts by weight of honey 5.
The preparation method of the postoperative Precerving liquid of tooth-implanting, comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:3 parts of Chinese violet, 2 parts of lampwick, 5 parts of lalang grass rhizome, 15 parts of reed rhizome, 6 parts of honeysuckle, flea stop 2 parts, 3 parts of radix glycyrrhizae;
(2) Chinese medicine material is crushed respectively, crosses 30 mesh sieves, stirred 20 minutes with 500 revs/min of rotating speed, obtain Chinese medicine Mixed powder;
(3) by Chinese medicine mixed powder and distilled water with solid-to-liquid ratio 1:50 (g/mL) are well mixed, in infrared power 200W, irradiation Infrared processing 10 minutes under distance 2cm process conditions, using 300 mesh filter-cloth filterings, concentrate the filtrate to concentration 0.8g/mL's Decoction, room temperature is cooled to, decoction is centrifuged 20 minutes with 5000 revs/min of rotating speed, supernatant is taken, obtains Chinese medicine extract;
(4) Chinese medicine extract, asparagus juice, zinc sulfate, sodium chloride and the honey of each parts by weight are weighed, into Chinese medicine extract Asparagus juice, zinc sulfate, sodium chloride and honey are added, is stirred 30 minutes with 500 revs/min of rotating speed, obtains mixed liquor;
(5) by mixed liquor ultra-high pressure sterilization, sterilization pressure 300MPa, normal temperature dwell time 10min are mixed after sterilization treatment Liquid is closed in 4 DEG C of preservations.
The asparagus juice is aloe juice, and the preparation process of the aloe juice is:Used from the middle part of aloe Pocket knife carefully cuts aloe leaf along aloe blade root, is rinsed well with the water of flowing, dries surface moisture;After cleaning up Aloe leaf input juice extractor in, stirred 2 minutes with 2000 revs/min of rotating speed, using the filter-cloth filtering of 300 mesh, obtained Juice;Juice is put in centrifuge and centrifuged 15 minutes with 8000 revs/min of rotating speed, supernatant is taken, produces.
Embodiment 2
The postoperative Precerving liquid of tooth-implanting, is formulated and is:The parts by weight of Chinese medicine extract 60, the parts by weight of asparagus juice 20, the weight of zinc sulfate 1 Part, the parts by weight of sodium chloride 3 and the parts by weight of honey 5.
The preparation method of the postoperative Precerving liquid of tooth-implanting, comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:3 parts of Chinese violet, 2 parts of lampwick, 5 parts of lalang grass rhizome, 15 parts of reed rhizome, 6 parts of honeysuckle, flea stop 2 parts, 3 parts of radix glycyrrhizae;
(2) Chinese medicine material is crushed respectively, crosses 30 mesh sieves, stirred 20 minutes with 500 revs/min of rotating speed, obtain Chinese medicine Mixed powder;
(3) the pectin enzyme aqueous solution of 3 times of Chinese medicine mixed powder weight, the pectin enzyme aqueous solution are added into Chinese medicine mixed powder The concentration of middle pectase is 0.1mg/mL, is reacted 2 minutes under conditions of pH 6,35 DEG C of temperature, 160 revs/min of rotating speed, will be anti- Answer liquid to use 300 mesh filter-cloth filterings, collect solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and distilled water with solid-to-liquid ratio 1:50 (g/mL) are well mixed, in infrared power 200W, Infrared processing 10 minutes under irradiation distance 2cm process conditions, using 300 mesh filter-cloth filterings, concentrate the filtrate to concentration 0.8g/ ML decoction, is cooled to room temperature, and decoction is centrifuged 20 minutes with 5000 revs/min of rotating speed, supernatant is taken, obtains traditional Chinese medicine extraction Liquid;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium chloride and the honey of each parts by weight are weighed, into Chinese medicine extract Asparagus juice, zinc sulfate, sodium chloride and honey are added, is stirred 30 minutes with 500 revs/min of rotating speed, obtains mixed liquor;
(6) by mixed liquor ultra-high pressure sterilization, sterilization pressure 300MPa, normal temperature dwell time 10min are mixed after sterilization treatment Liquid is closed in 4 DEG C of preservations.
The asparagus juice is aloe juice, and the preparation process of the aloe juice is:Used from the middle part of aloe Pocket knife carefully cuts aloe leaf along aloe blade root, is rinsed well with the water of flowing, dries surface moisture;After cleaning up Aloe leaf input juice extractor in, stirred 2 minutes with 2000 revs/min of rotating speed, using the filter-cloth filtering of 300 mesh, obtained Juice;Juice is put in centrifuge and centrifuged 15 minutes with 8000 revs/min of rotating speed, supernatant is taken, produces.
Embodiment 3
The postoperative Precerving liquid of tooth-implanting, is formulated and is:The parts by weight of Chinese medicine extract 60, the parts by weight of asparagus juice 20, the weight of zinc sulfate 1 Part, the parts by weight of sodium chloride 3 and the parts by weight of honey 5.
The preparation method of the postoperative Precerving liquid of tooth-implanting, comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:3 parts of Chinese violet, 2 parts of lampwick, 5 parts of lalang grass rhizome, 15 parts of reed rhizome, 6 parts of honeysuckle, flea stop 2 parts, 3 parts of radix glycyrrhizae;
(2) Chinese medicine material is crushed respectively, crosses 30 mesh sieves, stirred 20 minutes with 500 revs/min of rotating speed, obtain Chinese medicine Mixed powder;
(3) the pectin enzyme aqueous solution of 3 times of Chinese medicine mixed powder weight, the pectin enzyme aqueous solution are added into Chinese medicine mixed powder The concentration of middle pectase is 0.1mg/mL, is reacted 2 minutes under conditions of pH 6,35 DEG C of temperature, 160 revs/min of rotating speed, will be anti- Answer liquid to use 300 mesh filter-cloth filterings, collect solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and the polyalkylene glycol monoalkyl ether aqueous solution with solid-to-liquid ratio 1:50 (g/mL) mixing is equal Even, the mass fraction of polyalkylene glycol monoalkyl ether is 2.5% wherein in the polyalkylene glycol monoalkyl ether aqueous solution, in infrared power 200W, irradiation distance 2cm process conditions under infrared processing 10 minutes, using 300 mesh filter-cloth filterings, concentrate the filtrate to concentration 0.8g/mL decoction, is cooled to room temperature, and decoction is centrifuged 20 minutes with 5000 revs/min of rotating speed, supernatant is taken, in obtaining Medicament extracting solution;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium chloride and the honey of each parts by weight are weighed, into Chinese medicine extract Asparagus juice, zinc sulfate, sodium chloride and honey are added, is stirred 30 minutes with 500 revs/min of rotating speed, obtains mixed liquor;
(6) by mixed liquor ultra-high pressure sterilization, sterilization pressure 300MPa, normal temperature dwell time 10min are mixed after sterilization treatment Liquid is closed in 4 DEG C of preservations.
The asparagus juice is aloe juice, and the preparation process of the aloe juice is:Used from the middle part of aloe Pocket knife carefully cuts aloe leaf along aloe blade root, is rinsed well with the water of flowing, dries surface moisture;After cleaning up Aloe leaf input juice extractor in, stirred 2 minutes with 2000 revs/min of rotating speed, using the filter-cloth filtering of 300 mesh, obtained Juice;Juice is put in centrifuge and centrifuged 15 minutes with 8000 revs/min of rotating speed, supernatant is taken, produces.
Embodiment 4
The postoperative Precerving liquid of tooth-implanting, is formulated and is:The parts by weight of Chinese medicine extract 60, the parts by weight of asparagus juice 20, the weight of zinc sulfate 1 Part, the parts by weight of sodium chloride 3 and the parts by weight of honey 5.
The preparation method of the postoperative Precerving liquid of tooth-implanting, comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:3 parts of Chinese violet, 2 parts of lampwick, 5 parts of lalang grass rhizome, 15 parts of reed rhizome, 6 parts of honeysuckle, flea stop 2 parts, 3 parts of radix glycyrrhizae;
(2) Chinese medicine material is crushed respectively, crosses 30 mesh sieves, stirred 20 minutes with 500 revs/min of rotating speed, obtain Chinese medicine Mixed powder;
(3) the pectin enzyme aqueous solution of 3 times of Chinese medicine mixed powder weight, the pectin enzyme aqueous solution are added into Chinese medicine mixed powder The concentration of middle pectase is 0.1mg/mL, is reacted 2 minutes under conditions of pH 6,35 DEG C of temperature, 160 revs/min of rotating speed, will be anti- Answer liquid to use 300 mesh filter-cloth filterings, collect solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and the polyalkylene glycol monoalkyl ether aqueous solution with solid-to-liquid ratio 1:50 (g/mL) mixing is equal Even, the mass fraction of polyalkylene glycol monoalkyl ether is 2.5% wherein in the polyalkylene glycol monoalkyl ether aqueous solution, in infrared power 200W, irradiation distance 2cm process conditions under infrared processing 10 minutes, using 300 mesh filter-cloth filterings, concentrate the filtrate to concentration 0.8g/mL decoction, is cooled to room temperature, and decoction is centrifuged 20 minutes with 5000 revs/min of rotating speed, supernatant is taken, in obtaining Medicament extracting solution;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium chloride and the honey of each parts by weight are weighed, into Chinese medicine extract Asparagus juice, zinc sulfate, sodium chloride and honey are added, is stirred 30 minutes with 500 revs/min of rotating speed, obtains mixed liquor;
(6) by mixed liquor ultra-high pressure sterilization, sterilization pressure 300MPa, normal temperature dwell time 10min are mixed after sterilization treatment Liquid is closed in 4 DEG C of preservations.
The asparagus juice is Aloe gel juice, and the preparation process of the Aloe gel juice is:Used from the middle part of aloe Pocket knife carefully cuts aloe leaf along aloe blade root, is rinsed well with the water of flowing, dries surface moisture;After cleaning up Aloe leaf with parer cut off outer skin, obtain gel meat;Gel meat is put into juice extractor, with 2000 revs/min Rotating speed stir 2 minutes, using the filter-cloth filtering of 300 mesh, obtain juice;Juice is put in centrifuge with 8000 revs/min Rotating speed centrifuge 15 minutes, take supernatant, produce.
Embodiment 5
The postoperative Precerving liquid of tooth-implanting, is formulated and is:The parts by weight of Chinese medicine extract 60, the parts by weight of asparagus juice 20, the weight of zinc sulfate 1 Part, the parts by weight of sodium chloride 3 and the parts by weight of honey 5.
The preparation method of the postoperative Precerving liquid of tooth-implanting, comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:3 parts of Chinese violet, 2 parts of lampwick, 5 parts of lalang grass rhizome, 15 parts of reed rhizome, 6 parts of honeysuckle, flea stop 2 parts, 3 parts of radix glycyrrhizae;
(2) Chinese medicine material is crushed respectively, crosses 30 mesh sieves, stirred 20 minutes with 500 revs/min of rotating speed, obtain Chinese medicine Mixed powder;
(3) the pectin enzyme aqueous solution of 3 times of Chinese medicine mixed powder weight, the pectin enzyme aqueous solution are added into Chinese medicine mixed powder The concentration of middle pectase is 0.1mg/mL, is reacted 2 minutes under conditions of pH 6,35 DEG C of temperature, 160 revs/min of rotating speed, will be anti- Answer liquid to use 300 mesh filter-cloth filterings, collect solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and the polyalkylene glycol monoalkyl ether aqueous solution with solid-to-liquid ratio 1:50 (g/mL) mixing is equal Even, the mass fraction of polyalkylene glycol monoalkyl ether is 2.5% wherein in the polyalkylene glycol monoalkyl ether aqueous solution, in infrared power 200W, irradiation distance 2cm process conditions under infrared processing 10 minutes, using 300 mesh filter-cloth filterings, concentrate the filtrate to concentration 0.8g/mL decoction, is cooled to room temperature, and decoction is centrifuged 20 minutes with 5000 revs/min of rotating speed, supernatant is taken, in obtaining Medicament extracting solution;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium chloride and the honey of each parts by weight are weighed, into Chinese medicine extract Asparagus juice, zinc sulfate, sodium chloride and honey are added, is stirred 30 minutes with 500 revs/min of rotating speed, obtains mixed liquor;
(6) by mixed liquor ultra-high pressure sterilization, sterilization pressure 300MPa, normal temperature dwell time 10min are mixed after sterilization treatment Liquid is closed in 4 DEG C of preservations.
The asparagus juice is Aloe gel juice, and the preparation process of the Aloe gel juice is:Used from the middle part of aloe Pocket knife carefully cuts aloe leaf along aloe blade root, is rinsed well with the water of flowing, dries surface moisture;After cleaning up Aloe leaf with parer cut off outer skin, obtain gel meat;By gel meat mass fraction 0.05% mannosan Impregnated 10 seconds in the aqueous solution, take out, drain;
By in the gel meat input juice extractor after impregnation, stirred 2 minutes with 2000 revs/min of rotating speed, using 300 Purpose filter-cloth filtering, obtains juice;Juice is put in centrifuge and centrifuged 15 minutes with 8000 revs/min of rotating speed, takes supernatant Liquid, produce.
Embodiment 6
The postoperative Precerving liquid of tooth-implanting, is formulated and is:The parts by weight of Chinese medicine extract 60, the parts by weight of asparagus juice 20, the weight of zinc sulfate 1 Part, the parts by weight of sodium taurodeoxycholate 3 and the parts by weight of honey 5.
The preparation method of the postoperative Precerving liquid of tooth-implanting, comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:3 parts of Chinese violet, 2 parts of lampwick, 5 parts of lalang grass rhizome, 15 parts of reed rhizome, 6 parts of honeysuckle, flea stop 2 parts, 3 parts of radix glycyrrhizae;
(2) Chinese medicine material is crushed respectively, crosses 30 mesh sieves, stirred 20 minutes with 500 revs/min of rotating speed, obtain Chinese medicine Mixed powder;
(3) the pectin enzyme aqueous solution of 3 times of Chinese medicine mixed powder weight, the pectin enzyme aqueous solution are added into Chinese medicine mixed powder The concentration of middle pectase is 0.1mg/mL, is reacted 2 minutes under conditions of pH 6,35 DEG C of temperature, 160 revs/min of rotating speed, will be anti- Answer liquid to use 300 mesh filter-cloth filterings, collect solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and the polyalkylene glycol monoalkyl ether aqueous solution with solid-to-liquid ratio 1:50 (g/mL) mixing is equal Even, the mass fraction of polyalkylene glycol monoalkyl ether is 2.5% wherein in the polyalkylene glycol monoalkyl ether aqueous solution, in infrared power 200W, irradiation distance 2cm process conditions under infrared processing 10 minutes, using 300 mesh filter-cloth filterings, concentrate the filtrate to concentration 0.8g/mL decoction, is cooled to room temperature, and decoction is centrifuged 20 minutes with 5000 revs/min of rotating speed, supernatant is taken, in obtaining Medicament extracting solution;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium taurodeoxycholate and the honey of each parts by weight are weighed, to Chinese medicine Asparagus juice, zinc sulfate, sodium taurodeoxycholate and honey are added in extract solution, is stirred 30 minutes with 500 revs/min of rotating speed, Obtain mixed liquor;
(6) by mixed liquor ultra-high pressure sterilization, sterilization pressure 300MPa, normal temperature dwell time 10min are mixed after sterilization treatment Liquid is closed in 4 DEG C of preservations.
The asparagus juice is Aloe gel juice, and the preparation process of the Aloe gel juice is:Used from the middle part of aloe Pocket knife carefully cuts aloe leaf along aloe blade root, is rinsed well with the water of flowing, dries surface moisture;After cleaning up Aloe leaf with parer cut off outer skin, obtain gel meat;By gel meat mass fraction 0.05% mannosan Impregnated 10 seconds in the aqueous solution, take out, drain;
By in the gel meat input juice extractor after impregnation, stirred 2 minutes with 2000 revs/min of rotating speed, using 300 Purpose filter-cloth filtering, obtains juice;Juice is put in centrifuge and centrifuged 15 minutes with 8000 revs/min of rotating speed, takes supernatant Liquid, produce.
Embodiment 7
The postoperative Precerving liquid of tooth-implanting, is formulated and is:The parts by weight of Chinese medicine extract 60, the parts by weight of asparagus juice 20, the weight of zinc sulfate 1 Part, the parts by weight of sodium chloride 2, the parts by weight of sodium taurodeoxycholate 1 and the parts by weight of honey 5.
The preparation method of the postoperative Precerving liquid of tooth-implanting, comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:3 parts of Chinese violet, 2 parts of lampwick, 5 parts of lalang grass rhizome, 15 parts of reed rhizome, 6 parts of honeysuckle, flea stop 2 parts, 3 parts of radix glycyrrhizae;
(2) Chinese medicine material is crushed respectively, crosses 30 mesh sieves, stirred 20 minutes with 500 revs/min of rotating speed, obtain Chinese medicine Mixed powder;
(3) the pectin enzyme aqueous solution of 3 times of Chinese medicine mixed powder weight, the pectin enzyme aqueous solution are added into Chinese medicine mixed powder The concentration of middle pectase is 0.1mg/mL, is reacted 2 minutes under conditions of pH 6,35 DEG C of temperature, 160 revs/min of rotating speed, will be anti- Answer liquid to use 300 mesh filter-cloth filterings, collect solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and the polyalkylene glycol monoalkyl ether aqueous solution with solid-to-liquid ratio 1:50 (g/mL) mixing is equal Even, the mass fraction of polyalkylene glycol monoalkyl ether is 2.5% wherein in the polyalkylene glycol monoalkyl ether aqueous solution, in infrared power 200W, irradiation distance 2cm process conditions under infrared processing 10 minutes, using 300 mesh filter-cloth filterings, concentrate the filtrate to concentration 0.8g/mL decoction, is cooled to room temperature, and decoction is centrifuged 20 minutes with 5000 revs/min of rotating speed, supernatant is taken, in obtaining Medicament extracting solution;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium chloride, sodium taurodeoxycholate and the honeybee of each parts by weight are weighed Honey, asparagus juice, zinc sulfate, sodium chloride, sodium taurodeoxycholate and honey are added into Chinese medicine extract, with 500 revs/min Rotating speed stirs 30 minutes, obtains mixed liquor;
(6) by mixed liquor ultra-high pressure sterilization, sterilization pressure 300MPa, normal temperature dwell time 10min are mixed after sterilization treatment Liquid is closed in 4 DEG C of preservations.
The asparagus juice is Aloe gel juice, and the preparation process of the Aloe gel juice is:Used from the middle part of aloe Pocket knife carefully cuts aloe leaf along aloe blade root, is rinsed well with the water of flowing, dries surface moisture;After cleaning up Aloe leaf with parer cut off outer skin, obtain gel meat;By gel meat mass fraction 0.05% mannosan Impregnated 10 seconds in the aqueous solution, take out, drain;
By in the gel meat input juice extractor after impregnation, stirred 2 minutes with 2000 revs/min of rotating speed, using 300 Purpose filter-cloth filtering, obtains juice;Juice is put in centrifuge and centrifuged 15 minutes with 8000 revs/min of rotating speed, takes supernatant Liquid, produce.
The bacteriostasis property of the postoperative Precerving liquid of tooth-implanting of embodiment 7 is tested, carried out with reference to GB15979-2002, is surveyed Examination strain has Candida albicans, Escherichia coli and Pseudomonas aeruginosa.After tested, the Candida albicans bacteriostasis rate of embodiment 7 is 94.59%, Escherichia coli bacteriostasis rate is 96.24%, and Pseudomonas aeruginosa bacteriostasis rate is 92.47%.
Test case 1
Therapeutic effect test is carried out to the embodiment 1-7 postoperative Precerving liquid of tooth-implanting, selects the tooth-implanting of 35-64 year to suffer from Person, men and women respectively account for half, are randomly divided into 7 groups, every group 60.The state of an illness of patient meets situations below:Tooth-implanting is postoperative There is wound infection, have slight local swelling, oral hemorrhage, there is slight constant pain.Patient is in sex, age, the state of an illness Etc. without significant difference (P>0.05), there is comparativity.7 groups of patients use the embodiment 1-7 postoperative maintenance of tooth-implanting respectively Liquid, 2 times a day, each dosage 15mL are clean containing being told after gargling 3 minutes, are used continuously 2 weeks.
The therapeutic effect of patient is divided into effective, improvement and invalid Three Estate.It is 1. effective:The clinical symptoms of patient are basic Disappear, can be with normal life.2. take a turn for the better:The clinical symptoms of patient are clearly better.It is 3. invalid:The clinical symptoms of patient are not got better Turn, or serious complication occur.Specific test result is shown in Table 1.
Table 1:Therapeutic effect tables of data
It is effective Take a turn for the better It is invalid
Embodiment 1 22 30 8
Embodiment 2 26 28 6
Embodiment 3 29 26 5
Embodiment 4 31 26 3
Embodiment 5 33 24 3
Embodiment 6 31 25 4
Embodiment 7 35 24 1
Test case 2
The bacteriostasis property of the embodiment 1-6 postoperative Precerving liquid of tooth-implanting is tested, carried out with reference to GB15979-2002, Test strain has Candida albicans, Escherichia coli and Pseudomonas aeruginosa.Specific test result is shown in Table 2.
Table 2:Bacteriostasis property test result table
Candida albicans (%) Escherichia coli (%) Pseudomonas aeruginosa (%)
Embodiment 1 81.48 83.75 80.97
Embodiment 2 85.15 85.82 83.14
Embodiment 3 88.93 88.71 86.94
Embodiment 4 89.57 90.58 88.79
Embodiment 5 92.14 93.13 91.26
Embodiment 6 90.48 91.47 89.61
Test case 3
The solid content of embodiment 3-4 asparagus juice is tested, specific method of testing is:Weigh the addition of 6g samples Into measuring cup, after weighing, it is put into drying box, constant weight is dried in 60 DEG C.Solid content dry weight and the hundred of sample starting weight Divide ratio, the as content of solid content.Specific test result is shown in Table 3.
Table 3:Solid content test result table
Solid content (%)
Embodiment 3 3.57
Embodiment 4 1.03
It is seen from the above data that the present invention prepares Chinese medicine extract, extraction time using infra-red radiation as thermal source Short, extraction efficiency is high.It is effective to Chinese herbal medicine because vegetalitas Chinese medicine cell membrane is made up of cellulose, hemicellulose and pectin etc. Discharge composition and cause certain obstacle.Embodiment 2 prepares Chinese medicine extract using infrared assistance enzymolysis method, and pectase acts on Cell membrane, break the integrality of its structure, active components of plants is had higher extraction efficiency.Embodiment 3 uses nonionic table Face aqueous surfactant solutions substitute the extraction that distilled water is used for Chinese medicine, and nonionic surfactant swelling vegetable material can be more thorough Ground is diffused into solid matrix, adds the mass tranfer coefficient that soluble component is desorbed into water from plant substrates.In addition, infrared ray Intramolecular heating effect be Chinese herbal medicine in active ingredient and surfactant solution between interaction provide convenience. The therapeutic effect and fungistatic effect difference of embodiment 3 and embodiment 4 be not notable, because aloe juice and aloe gel Active component content is mainly polyoses content difference and few in juice.But the solid content of the aloe juice of embodiment 3 More than the solid content of the Aloe gel juice of embodiment 4, this may due to containing some labile elements in aloe juice, Cause to precipitate after heating, these compositions are probably not have centrifugation thoroughly cellulose, solubility during raw material makes Hemicellulose and soluble protein.The therapeutic effect and fungistatic effect of embodiment 5 are better than embodiment 4, this be probably due to Aloe gel meat after impregnation, strengthens its fungistatic effect in mannosan, while avoids the activity of aloe in juice-extracting process Composition is destroyed.

Claims (10)

1. a kind of postoperative Precerving liquid of tooth-implanting, it is characterised in that including Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and honeybee Honey.
2. the postoperative Precerving liquid of tooth-implanting according to claim 1, it is characterised in that by the raw material preparation of following weight parts Into:Chinese medicine extract 50-60 parts, asparagus juice 15-20 parts, zinc sulfate 1-3 parts, sodium salt 3-5 parts and honey 3-5 parts.
3. the postoperative Precerving liquid of tooth-implanting according to claim 2, it is characterised in that the system of the postoperative Precerving liquid of tooth-implanting Preparation Method comprises the following steps:
(1) Chinese medicine material of each parts by weight is weighed by formula:Chinese violet 3-5 parts, lampwick 1-3 parts, lalang grass rhizome 5-10 parts, reed rhizome 15-20 parts, honeysuckle 6-10 parts, flea stop 1-3 parts, radix glycyrrhizae 3-5 parts;
(2) Chinese medicine material is crushed respectively, crosses 20-30 mesh sieves, 10-20 minutes are stirred with 300-500 revs/min of rotating speed, obtained To Chinese medicine mixed powder;
(3) by Chinese medicine mixed powder and distilled water with solid-to-liquid ratio 1:(50-80) (g/mL) is well mixed, in infrared power 150- 200W, irradiation distance 2-4cm process conditions under infrared processing 5-10 minutes, it is using 300-400 mesh filter-cloth filterings, filtrate is dense Concentration 0.6-0.8g/mL decoction is reduced to, is cooled to room temperature, decoction is centrifuged into 10-20 with 4000-5000 revs/min of rotating speed Minute, supernatant is taken, obtains Chinese medicine extract;
(4) Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and the honey of each parts by weight are weighed, reed is added into Chinese medicine extract Luxuriant growth juice, zinc sulfate, sodium salt and honey, 20-40 minutes are stirred with 300-500 revs/min of rotating speed, obtain mixed liquor;
(5) by mixed liquor sterilization treatment after 4-10 DEG C of preservation.
4. the postoperative Precerving liquid of tooth-implanting according to claim 2, it is characterised in that the system of the postoperative Precerving liquid of tooth-implanting Preparation Method comprises the following steps:
(1) raw material of each parts by weight is weighed by formula:Chinese violet 3-5 parts, lampwick 1-3 parts, lalang grass rhizome 5-10 parts, reed rhizome 15-20 Part, honeysuckle 6-10 parts, flea stop 1-3 parts, radix glycyrrhizae 3-5 parts;
(2) Chinese medicine material is crushed respectively, crosses 20-30 mesh sieves, 10-20 minutes are stirred with 300-500 revs/min of rotating speed, obtained To Chinese medicine mixed powder;
(3) the pectin enzyme aqueous solution of 3-5 times of Chinese medicine mixed powder weight is added into Chinese medicine mixed powder, in the pectin enzyme aqueous solution The concentration of pectase is 0.1-0.2mg/mL, anti-under conditions of pH 6-7,25-35 DEG C of temperature, 100-200 revs/min of rotating speed 2-3 minutes are answered, reaction solution is used into 200-300 mesh filter-cloth filterings, collects solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and distilled water with solid-to-liquid ratio 1:(50-80) (g/mL) is well mixed, in infrared power 150- 200W, irradiation distance 2-4cm process conditions under infrared processing 5-10 minutes, it is using 300-400 mesh filter-cloth filterings, filtrate is dense Concentration 0.6-0.8g/mL decoction is reduced to, is cooled to room temperature, decoction is centrifuged into 10-20 with 4000-5000 revs/min of rotating speed Minute, supernatant is taken, obtains Chinese medicine extract;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and the honey of each parts by weight are weighed, reed is added into Chinese medicine extract Luxuriant growth juice, zinc sulfate, sodium salt and honey, 20-40 minutes are stirred with 300-500 revs/min of rotating speed, obtain mixed liquor;
(6) by mixed liquor sterilization treatment after 4-10 DEG C of preservation.
5. the postoperative Precerving liquid of tooth-implanting according to claim 2, it is characterised in that the system of the postoperative Precerving liquid of tooth-implanting Preparation Method comprises the following steps:
(1) raw material of each parts by weight is weighed by formula:Chinese violet 3-5 parts, lampwick 1-3 parts, lalang grass rhizome 5-10 parts, reed rhizome 15-20 Part, honeysuckle 6-10 parts, flea stop 1-3 parts, radix glycyrrhizae 3-5 parts;
(2) Chinese medicine material is crushed respectively, crosses 20-30 mesh sieves, 10-20 minutes are stirred with 300-500 revs/min of rotating speed, obtained To Chinese medicine mixed powder;
(3) the pectin enzyme aqueous solution of 3-5 times of Chinese medicine mixed powder weight is added into Chinese medicine mixed powder, in the pectin enzyme aqueous solution The concentration of pectase is 0.1-0.2mg/mL, anti-under conditions of pH 6-7,25-35 DEG C of temperature, 100-200 revs/min of rotating speed 2-3 minutes are answered, reaction solution is used into 200-300 mesh filter-cloth filterings, collects solid, the Chinese medicine after being digested;
(4) by the Chinese medicine after enzymolysis and the polyalkylene glycol monoalkyl ether aqueous solution with solid-to-liquid ratio 1:(50-80) (g/mL) mixing is equal Even, the mass fraction of polyalkylene glycol monoalkyl ether is 2.5-5% wherein in the polyalkylene glycol monoalkyl ether aqueous solution, in infrared power 150-200W, irradiation distance 2-4cm process conditions under infrared processing 5-10 minutes, using 300-400 mesh filter-cloth filterings, will filter Liquid is concentrated into concentration 0.6-0.8g/mL decoction, is cooled to room temperature, and decoction is centrifuged with 4000-5000 revs/min of rotating speed 10-20 minutes, supernatant is taken, obtain Chinese medicine extract;
(5) Chinese medicine extract, asparagus juice, zinc sulfate, sodium salt and the honey of each parts by weight are weighed, reed is added into Chinese medicine extract Luxuriant growth juice, zinc sulfate, sodium salt and honey, 20-40 minutes are stirred with 300-500 revs/min of rotating speed, obtain mixed liquor;
(6) by mixed liquor sterilization treatment after 4-10 DEG C of preservation.
6. the postoperative Precerving liquid of tooth-implanting according to any one of claim 2-5, it is characterised in that the sodium salt is chlorination Sodium and/or sodium taurodeoxycholate.
7. the postoperative Precerving liquid of tooth-implanting according to claim 6, it is characterised in that the asparagus juice is aloe juice, The preparation process of the aloe juice is:Aloe leaf is cut along aloe blade root from the middle part of aloe with pocket knife, is used The water of flowing is rinsed well, dries surface moisture;In aloe leaf input juice extractor after cleaning up, with 1800-2000 Rev/min rotating speed stirring 2-3 minutes, using the filter-cloth filtering of 200-300 mesh, obtain juice;Juice is put in centrifuge To centrifuge 10-15 minutes under 8000-10000 revs/min of rotating speed, supernatant is taken, is produced.
8. the postoperative Precerving liquid of tooth-implanting according to claim 6, it is characterised in that the asparagus juice is Aloe gel juice, The preparation process of the Aloe gel juice is:Aloe leaf is cut along aloe blade root from the middle part of aloe with pocket knife, is used The water of flowing is rinsed well, dries surface moisture;Aloe leaf after cleaning up is cut off into outer skin with parer, obtained Gel meat;Gel meat is put into juice extractor, 2-3 minutes are stirred with 1800-2000 revs/min of rotating speed, using 200-300 mesh Filter-cloth filtering, obtain juice;Juice is put in centrifuge to centrifuge 10-15 points under 8000-10000 revs/min of rotating speed Clock, supernatant is taken, produced.
9. the postoperative Precerving liquid of tooth-implanting according to claim 8, it is characterised in that by aloe gel meat in quality before squeezing the juice The 10-20 seconds are impregnated in the fraction 0.05-0.1% mannosan aqueous solution, takes out, drains.
10. a kind of postoperative maintenance method of tooth-implanting, it is characterised in that using any postoperative guarantor of tooth-implanting in claim 1-9 Nutrient solution is gargled, daily 2-3 times, each dosage 10-15mL, containing being told totally after gargling 2-3 minutes, is used continuously 2-3 weeks.
CN201710692939.2A 2017-08-14 2017-08-14 Postoperative maintenance liquid for dental implant and postoperative maintenance method for dental implant Expired - Fee Related CN107441020B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710692939.2A CN107441020B (en) 2017-08-14 2017-08-14 Postoperative maintenance liquid for dental implant and postoperative maintenance method for dental implant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710692939.2A CN107441020B (en) 2017-08-14 2017-08-14 Postoperative maintenance liquid for dental implant and postoperative maintenance method for dental implant

Publications (2)

Publication Number Publication Date
CN107441020A true CN107441020A (en) 2017-12-08
CN107441020B CN107441020B (en) 2020-09-29

Family

ID=60491959

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710692939.2A Expired - Fee Related CN107441020B (en) 2017-08-14 2017-08-14 Postoperative maintenance liquid for dental implant and postoperative maintenance method for dental implant

Country Status (1)

Country Link
CN (1) CN107441020B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112931858A (en) * 2021-03-05 2021-06-11 佳木斯大学 Preparation method of nutritional meal suitable for postoperative recovery of maxillofacial trauma
CN114404332A (en) * 2022-01-24 2022-04-29 河南豫兰贵人实业有限公司 Oral cavity bacteriostatic gel and oral cavity beautifying health care method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008122286A1 (en) * 2007-04-04 2008-10-16 Gumlink A/S Center-filled chewing gum product for dental care
CN102639100A (en) * 2009-08-20 2012-08-15 托马斯·贝尔纳多·加尔万冈萨雷斯 Antiseptic pharmaceutical composition for oral hygiene and the treatment of oral diseases of microbial origin
CN106726913A (en) * 2016-12-12 2017-05-31 上海芽庄奇楠酒业有限公司 A kind of Agilawood toothpaste and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008122286A1 (en) * 2007-04-04 2008-10-16 Gumlink A/S Center-filled chewing gum product for dental care
CN102639100A (en) * 2009-08-20 2012-08-15 托马斯·贝尔纳多·加尔万冈萨雷斯 Antiseptic pharmaceutical composition for oral hygiene and the treatment of oral diseases of microbial origin
CN106726913A (en) * 2016-12-12 2017-05-31 上海芽庄奇楠酒业有限公司 A kind of Agilawood toothpaste and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
董银卯等: "《芦荟加工技术及其管理规范》", 30 November 2001, 上海科学普及出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112931858A (en) * 2021-03-05 2021-06-11 佳木斯大学 Preparation method of nutritional meal suitable for postoperative recovery of maxillofacial trauma
CN114404332A (en) * 2022-01-24 2022-04-29 河南豫兰贵人实业有限公司 Oral cavity bacteriostatic gel and oral cavity beautifying health care method

Also Published As

Publication number Publication date
CN107441020B (en) 2020-09-29

Similar Documents

Publication Publication Date Title
Hajdu et al. An ethnopharmacological survey of the traditional medicine utilized in the community of Porvenir, Bajo Paraguá Indian Reservation, Bolivia
Somboro et al. An ethnobotanical and phytochemical study of the African medicinal plant Guiera senegalensis JF Gmel
KR101176590B1 (en) Herbal Composition for Removing Hangover and Beverage Containing the Same
CN102178844B (en) Oral Chinese medicine preparation for treating gum swelling and pain and preparation method thereof
Hirschhorn Botanical remedies of the former Dutch East Indies (Indonesia). Part I: Eumycetes, pteridophyta, gymnospermae, angiospermae (monocotyledones only)
CN105770191B (en) With the composition and its preparation method and application for reducing Periodontal Pathogens active function
KR20020041639A (en) Compositions effective for removing hangover which contains natural herb tea extracts and health supplementing foods containing the same as an effective ingredient
Singh et al. Folk medicinal plants in the Sikkim Himalayas of India
Singh et al. Ethnomedicinal value of traditional food plants used by the Zeliang tribe of Nagaland
Mawla et al. Ethnomedicinal plants of folk medicinal practitioners in four villages of Natore and Rajshahi districts, Bangladesh
CN111973515A (en) Bacteriostatic restoration plant extraction composition, preparation method and application thereof
Dharani et al. An Illustrated Guide to Medicinal Plants of East Africa
Sukumaran et al. Usage of medicinal plants by two cultural communities of Kanyakumari district, Tamil Nadu, South India
Akwaji et al. Ethnobotanical survey of commonly used medicinal plants in Northern Cross River State, Nigeria
WO2017219846A1 (en) Externally-used traditional chinese medicine preparation for treating rhinitis, and preparation method therefor
CN107441020A (en) The postoperative Precerving liquid of tooth-implanting and the postoperative maintenance method of tooth-implanting
JPH0616530A (en) Cosmetic
CN107007688A (en) Treat medicinal herb spray of oral inflammation and preparation method thereof
KR20080035848A (en) Beauty soap composition for improving skin
US5980903A (en) Composition for the treatment of viral infections including HIV
KR100609643B1 (en) Herbal medicine composition for the treatment of dermatitis and a method of manufacturing the same
Hirschhorn Botanical remedies of the former Dutch East Indies (Indonesia). Part II: Dicotyledones up to and including leguminosae
JP4673220B2 (en) Herbal composition for digestive disorders
CN110772598A (en) Composition for treating aphtha, application and taking method thereof
JPH0773478B2 (en) Method for producing health food composition

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20200929

Termination date: 20210814