CN107440912A - The preparation method of dental prosthetic material - Google Patents
The preparation method of dental prosthetic material Download PDFInfo
- Publication number
- CN107440912A CN107440912A CN201710657626.3A CN201710657626A CN107440912A CN 107440912 A CN107440912 A CN 107440912A CN 201710657626 A CN201710657626 A CN 201710657626A CN 107440912 A CN107440912 A CN 107440912A
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- Prior art keywords
- nano diamond
- rosemary
- ethanol
- preparation
- prosthetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
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- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Dental Preparations (AREA)
Abstract
The invention discloses a kind of preparation method of dental prosthetic material, comprise the following steps：（1）Prefabricated Nano diamond aggregate；（2）Preparation containing functionalized surface group Nano diamond；（3）Modified grafting：By the step（2）In obtain put into containing functionalized surface group Nano diamond into modified grafting agent, the modified grafting agent is epoxy acrylate, obtains modified Nano diamond；（4）Product is made：Using supersonic oscillations, by the step（3）Obtained modified Nano diamond is added into ethanol solution, vacuumizes sinter molding after drying, that is, product is made.After modified grafting, it is favorably improved obtained dental prosthetic material in machinability and anti-microbial property；Dental prosthetic material machinability of the invention is excellent, stability is good.
Description
Technical field
The invention belongs to field of biomedicine technology, more particularly, to a kind of preparation method of dental prosthetic material.
Background technology
Tooth is that one kind is moved in structure present on many animals, the mankind, amphibian animal, reptiles, birds and high lactation
The organ of thing laboratory rodent chow.Tooth is the most hard organ of human body.In general, tooth is white（Normal person is slightly micro-
Yellow）, quality is hard.The variously-shaped of tooth is applied to multiple use, including tear, grate foods.Tooth is that animal is born
Self-protection arms.Human language pronounces and the tooth above and below front row in mouth（Front tooth）Closely related, ancient Han nationality's standard speech is referred to as " refined
Speech ".Tooth it is clean and tidy, or even be related to doings and status.
Tooth can not only laboratory rodent chow, help, and have a significant impact to U.S.A of face.Due to tooth and alveolar bone
Support, Arch width and occluding relation it is normal, the face and lip and cheek that can just make people seem plentiful.And when people speech and
During smile, neat and pure white tooth, it can more show the healthy and beautiful of people.On the contrary, if Dental arch growth were abnormal, row of teeth
Row are disorderly, and uneven, face will seem uncoordinated.If absence of tooth is too many, lip and cheek loses support and is recessed, will
The face of people is set to present a weathered appearance, become thin.So people are often using tooth as one of important symbol for weighing fitness.
Dental Erosion be on the basis of the tissue of tooth having destroyed or seriously undermined is removed, according to maintenance, drag and
The principle of protection dental pulp-dentine organ prepares tooth；Finally, its intrinsic shape of certain program recovery is passed through with certain material
State and function.During Dental Erosion, prepared from being designed into, each specific steps, operation, it is necessary to take dental tissue into account
Retain.The medical practice for enabling defect of teeth part to recover.The reason for causing defect of teeth is mainly carious tooth, is secondly outer
Wound, abrasion, acid etching etc..Restorative procedure can be repaiied according to defect of teeth situation and using material context from resin reparation, full porcelain
Multiple, Ceramic prosthesis etc..
In Chinese patent literature CN105886868A, disclose a kind of Nano diamond enhancing titanium matrix composite and its
Preparation method and application.The composite is mainly as made by Nano diamond and matrix titanium, wherein the nanogold is firm
Masonry is enhancing phase, is dispersed in the matrix of Titanium and plays dispersion-strengthened action.
But the repair materials that above-mentioned technical proposal obtains still have on machinability and antibacterial ability and stability
Undesirable part, is further improved.
The content of the invention
The problem to be solved in the present invention is to propose a kind of machinability is excellent, stability is good dental prosthetic material
Preparation method.
In order to solve the above technical problems, the technical solution adopted by the present invention is：The preparation method of the dental prosthetic material, bag
Include following steps：
（1）Prefabricated Nano diamond aggregate：Nano diamond original powder is ground in the case where drying vacuum environment, obtains granularity
Homogeneous Nano diamond aggregate, and be dispersed in ethanol solution, obtain Nano diamond ethanol solution mixture；
（2）Preparation containing functionalized surface group Nano diamond：To the step（1）Nano diamond ethanol solution mix
Rosemary ethanol extract is added in compound, in 25 DEG C of stirring reaction 20min, is centrifuged, obtains the ethanol extraction of rosemary
The Nano diamond of thing functionalization, i.e., containing functionalized surface group Nano diamond；
（3）Modified grafting：By the step（2）In obtain containing functionalized surface group Nano diamond put into modification connect
In branch agent, the modified grafting agent is epoxy acrylate, obtains modified Nano diamond；
（4）Product is made：Using supersonic oscillations, by the step（3）Obtained modified Nano diamond adds molten to ethanol
In liquid, sinter molding after drying is vacuumized, that is, product is made；
In the step（2）In the preparation method of rosemary ethanol extract be：The rosemary for being dried to constant weight is crushed
After machine crushes, weigh after appropriate powder from rosemary mix with 50% ethanol, using ultrasonic extraction mode, obtain containing rosemary work
The extraction solution of property composition, after the extract solution is concentrated with Rotary Evaporators, obtains rosemary ethanol extract.
Nano diamond original powder is ground in the case where drying vacuum environment, the Nano diamond for obtaining homogeneous grain diameter is reunited
Body, and be dispersed in ethanol solution, moisture aerobic environment is avoided contact with process of lapping, obtained aggregate specification performance
More preferably, it is dispersed in ethanol solution, prevents aggregate is sent with other extraneous materials from reacting, and be advantageous to functionalized surface group
The preparation of Nano diamond；The modified specific reaction mechanism of grafting is also unknown at present, shows that it contributes to according to the research of inventor
Dental prosthetic material is in machinability and anti-microbial property made from raising；In step（4）In, supersonic oscillations cause modified gold
Hard rock is fully merged in ethanol solution with matrix titanium and is integrally formed.
Preferably, in the step（4）In, modified Nano diamond is added into ethanol solution while adds edible
Pigment；Various colors can be made, realize personalized designs.
Preferably, in the step（2）In the preparation method of rosemary ethanol extract be：The fan of constant weight will be dried to
Repeatedly it is fragrant crushed with pulverizer after, weigh after 10g powder from rosemary mixes with 200 milliliter 50% of ethanol, using ultrasonic extraction side
Formula, in 40 DEG C, extract 2 hours, obtain the extraction solution of the active component containing rosemary, the extract solution is carried out with Rotary Evaporators
After concentration, rosemary ethanol extract is obtained.
Preferably, in the step（3）In, obtained modified Nano diamond simultaneously adds poly- tetravinyl pyridine and bromo
Alkane is reacted, by reaction product using ether precipitation, washing, dry quaternized Nano diamond after centrifugation, then
Carry out the step（4）, quaternized Nano diamond is added into ethanol solution.
Handled by above-mentioned steps, quaternized Nano diamond is added into ethanol solution, is disperseed more stable.
Preferably, reaction temperature is 50 DEG C~70 DEG C, reaction time 16h~24h.
Embodiment
Embodiment 1：The preparation method of dental prosthetic material comprises the following steps：
（1）Prefabricated Nano diamond aggregate：Nano diamond original powder is ground in the case where drying vacuum environment, obtains granularity
Homogeneous Nano diamond aggregate, and be dispersed in ethanol solution, obtain Nano diamond ethanol solution mixture；
（2）Preparation containing functionalized surface group Nano diamond：To the step（1）Nano diamond ethanol solution mix
Rosemary ethanol extract is added in compound, in 25 DEG C of stirring reaction 20min, is centrifuged, obtains the ethanol extraction of rosemary
The Nano diamond of thing functionalization, i.e., containing functionalized surface group Nano diamond；
（3）Modified grafting：By the step（2）In obtain containing functionalized surface group Nano diamond put into modification connect
In branch agent, the modified grafting agent is epoxy acrylate, obtains modified Nano diamond；
（4）Product is made：Using supersonic oscillations, by the step（3）Obtained modified Nano diamond adds molten to ethanol
In liquid, sinter molding after drying is vacuumized, that is, product is made；
In the step（2）In the preparation method of rosemary ethanol extract be：The rosemary for being dried to constant weight is crushed
After machine crushes, weigh after appropriate powder from rosemary mix with 50% ethanol, using ultrasonic extraction mode, obtain containing rosemary work
The extraction solution of property composition, after the extract solution is concentrated with Rotary Evaporators, obtains rosemary ethanol extract.
Wherein, step in the present embodiment（2）In, weigh after 10g powder from rosemary mixes with 200 milliliter 50% of ethanol,
Using ultrasonic extraction mode, in 40 DEG C, extract 2 hours.
Product is made to soak 60 days in the solution that pH value is 5, surface nondestructive wound, through pressure test, compression resistance is without obvious
Change, stable performance.
Embodiment 2：As different from Example 1, in the step（4）In, modified Nano diamond is added to ethanol
Edible pigment is added in solution simultaneously.
It is same as Example 1 to test effect.
Embodiment 3：As different from Example 1, in the step（3）In, obtained modified Nano diamond simultaneously adds
Poly- tetravinyl pyridine and brominated alkanes are reacted, dry after centrifugation by reaction product using ether precipitation, washing
Quaternized Nano diamond, then carry out the step（4）, quaternized Nano diamond is added into ethanol solution.
After tested, quaternized Nano diamond is added into ethanol solution, and scattered more stable, after 90 days, solution is without bright
Aobvious change, other performance tests are same as Example 1.
In addition, in the present embodiment, obtained modified Nano diamond simultaneously adds poly- tetravinyl pyridine and brominated alkanes
The temperature reacted is 50 DEG C~70 DEG C, reaction time 16h~24h.
Claims (5)
1. a kind of preparation method of dental prosthetic material, it is characterised in that comprise the following steps：
（1）Prefabricated Nano diamond aggregate：Nano diamond original powder is ground in the case where drying vacuum environment, obtains granularity
Homogeneous Nano diamond aggregate, and be dispersed in ethanol solution, obtain Nano diamond ethanol solution mixture；
（2）Preparation containing functionalized surface group Nano diamond：To the step（1）Nano diamond ethanol solution mix
Rosemary ethanol extract is added in compound, in 25 DEG C of stirring reaction 20min, is centrifuged, obtains the ethanol extraction of rosemary
The Nano diamond of thing functionalization, i.e., containing functionalized surface group Nano diamond；
（3）Modified grafting：By the step（2）In obtain containing functionalized surface group Nano diamond put into modification connect
In branch agent, the modified grafting agent is epoxy acrylate, obtains modified Nano diamond；
（4）Product is made：Using supersonic oscillations, by the step（3）Obtained modified Nano diamond adds molten to ethanol
In liquid, sinter molding after drying is vacuumized, that is, product is made；
In the step（2）In the preparation method of rosemary ethanol extract be：The rosemary for being dried to constant weight is crushed
After machine crushes, weigh after appropriate powder from rosemary mix with 50% ethanol, using ultrasonic extraction mode, obtain containing rosemary work
The extraction solution of property composition, after the extract solution is concentrated with Rotary Evaporators, obtains rosemary ethanol extract.
2. the preparation method of dental prosthetic material according to claim 1, it is characterised in that in the step（4）In, it will change
Property Nano diamond adds into ethanol solution while adds edible pigment.
3. the preparation method of dental prosthetic material according to claim 1, it is characterised in that in the step（2）In fan
Repeatedly the preparation method of fragrant ethanol extract is：After the rosemary for being dried to constant weight is crushed with pulverizer, 10g rosemary powder is weighed
After end mixes with 200 milliliter 50% of ethanol, using ultrasonic extraction mode, in 40 DEG C, extract 2 hours, obtain containing rosemary activity
The extraction solution of composition, after the extract solution is concentrated with Rotary Evaporators, obtain rosemary ethanol extract.
4. the preparation method of dental prosthetic material according to claim 1, it is characterised in that in the step（3）In, obtain
Modified Nano diamond and add poly- tetravinyl pyridine and brominated alkanes and reacted, reaction product is sunk using ether
Form sediment, washing, dry quaternized Nano diamond after centrifugation, then carry out the step（4）, by quaternized Nano diamond
Add into ethanol solution.
5. the preparation method of dental prosthetic material according to claim 4, it is characterised in that reaction temperature is 50 DEG C~70
DEG C, reaction time 16h~24h.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710657626.3A CN107440912A (en) | 2017-08-03 | 2017-08-03 | The preparation method of dental prosthetic material |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710657626.3A CN107440912A (en) | 2017-08-03 | 2017-08-03 | The preparation method of dental prosthetic material |
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| CN107440912A true CN107440912A (en) | 2017-12-08 |
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| CN201710657626.3A Pending CN107440912A (en) | 2017-08-03 | 2017-08-03 | The preparation method of dental prosthetic material |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11517408B2 (en) | 2019-10-23 | 2022-12-06 | Imam Abdulrahman Bin Faisal University | Method for treating denture stomatitis using denture base material containing nanodiamonds |
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| KR20100125746A (en) * | 2009-05-21 | 2010-12-01 | (주)티피에스 | Method manufacturing diamond wire for processing semiconductor materials and diamond wire manufactured by the method |
| CN103627234A (en) * | 2013-06-21 | 2014-03-12 | 宁波墨西科技有限公司 | Novel nanometer diamond heat-conducting coating and preparation method thereof |
| CN105253882A (en) * | 2015-10-09 | 2016-01-20 | 南京理工大学 | Ultra-dispersed anti-bacterial nanometer diamond material and preparation method thereof |
| CN105542561A (en) * | 2016-03-01 | 2016-05-04 | 蒋彩云 | Antibacterial water-based ink and preparation method thereof |
| CN105886868A (en) * | 2016-05-09 | 2016-08-24 | 东南大学 | Nano-diamond reinforced titanium-based composite material as well as preparation method and application thereof |
-
2017
- 2017-08-03 CN CN201710657626.3A patent/CN107440912A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100125746A (en) * | 2009-05-21 | 2010-12-01 | (주)티피에스 | Method manufacturing diamond wire for processing semiconductor materials and diamond wire manufactured by the method |
| CN103627234A (en) * | 2013-06-21 | 2014-03-12 | 宁波墨西科技有限公司 | Novel nanometer diamond heat-conducting coating and preparation method thereof |
| CN105253882A (en) * | 2015-10-09 | 2016-01-20 | 南京理工大学 | Ultra-dispersed anti-bacterial nanometer diamond material and preparation method thereof |
| CN105542561A (en) * | 2016-03-01 | 2016-05-04 | 蒋彩云 | Antibacterial water-based ink and preparation method thereof |
| CN105886868A (en) * | 2016-05-09 | 2016-08-24 | 东南大学 | Nano-diamond reinforced titanium-based composite material as well as preparation method and application thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11517408B2 (en) | 2019-10-23 | 2022-12-06 | Imam Abdulrahman Bin Faisal University | Method for treating denture stomatitis using denture base material containing nanodiamonds |
| US11751982B2 (en) | 2019-10-23 | 2023-09-12 | Imam Abdulrahman Bin Faisal University | Nanodiamond-containing composite material for denture construction |
| US11844659B2 (en) | 2019-10-23 | 2023-12-19 | Imam Abdulrahman Bin Faisal University | Denture or removable dental prosthetic made from composite material |
| US11850108B2 (en) | 2019-10-23 | 2023-12-26 | Imam Abdulrahman Bin Faisal University | Method for making composite denture material |
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Application publication date: 20171208 |
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