CN107432960B - Spiral diversion integrated film type oxygenator - Google Patents
Spiral diversion integrated film type oxygenator Download PDFInfo
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- CN107432960B CN107432960B CN201710817398.1A CN201710817398A CN107432960B CN 107432960 B CN107432960 B CN 107432960B CN 201710817398 A CN201710817398 A CN 201710817398A CN 107432960 B CN107432960 B CN 107432960B
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- annular
- spiral
- blood
- oxygenation
- annular partition
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- 239000008280 blood Substances 0.000 claims abstract description 112
- 210000004369 blood Anatomy 0.000 claims abstract description 112
- 239000012528 membrane Substances 0.000 claims abstract description 84
- 238000006213 oxygenation reaction Methods 0.000 claims abstract description 57
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 21
- 239000001301 oxygen Substances 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
- 238000005192 partition Methods 0.000 claims description 98
- 239000012510 hollow fiber Substances 0.000 claims description 28
- 230000004888 barrier function Effects 0.000 claims description 9
- 210000004204 blood vessel Anatomy 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 2
- 238000009792 diffusion process Methods 0.000 abstract description 11
- 230000008859 change Effects 0.000 description 12
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 10
- 125000006850 spacer group Chemical group 0.000 description 10
- 230000017531 blood circulation Effects 0.000 description 8
- 230000000903 blocking effect Effects 0.000 description 6
- 229910002092 carbon dioxide Inorganic materials 0.000 description 5
- 239000001569 carbon dioxide Substances 0.000 description 5
- 230000004087 circulation Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000835 fiber Substances 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000007789 gas Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 208000010496 Heart Arrest Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000013130 cardiovascular surgery Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3666—Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
Abstract
The invention relates to a spiral diversion integrated membrane oxygenator which comprises a lower cover, an oxygenation part and an upper cover, wherein the lower cover is provided with an air outlet pipe; the oxygenation part is arranged on the lower cover and comprises a mandrel structure, an oxygenation shell and an oxygenation silk membrane structure, the oxygenation shell is provided with a blood outlet tube, and the blood outlet tube is close to the lower cover; the upper cover is arranged on the oxygenation part and is provided with a blood inlet pipe and an oxygen inlet pipe; the central spindle structure comprises a central spindle body and an annular guide plate, wherein the central spindle body is provided with a first end part and a second end part, a blood channel is arranged between the first end part and the upper cover, the annular guide plate is sleeved on the central spindle body, and the annular guide plate is provided with at least one blood through hole and at least one spiral guide groove which are annularly arranged. The dabber structure of the spiral water conservancy diversion integrated film oxygenator of this application is through the annular guide plate guide blood diffusion of the water conservancy diversion structure that has spiral guiding gutter, increases area of contact and diffusion area of blood and silk membrane structure, promotes the utilization ratio of silk membrane structure.
Description
Technical Field
The invention relates to the technical field of medical instrument products, in particular to a spiral diversion integrated membrane type oxygenator.
Background
The membrane oxygenator is a medical instrument for replacing lungs by cardiac arrest, has the function of regulating the oxygen and carbon dioxide content in blood, is a necessary medical device for cardiovascular surgery, and is also a necessary medical device for treating acute respiratory diseases and waiting for a lung transplantation stage. The membrane oxygenator is based on the principle that venous blood in a body is led out of the body, oxygen and carbon dioxide are exchanged after passing through the membrane oxygenator to become arterial blood, and then arterial system of a patient is returned, so that supply of oxygenated blood of organ tissues of the human body is maintained, lung effect is temporarily replaced in the operation process, and meanwhile, a quiet, bloodless and clear operation environment is provided for doctors, so that the operation is conveniently implemented.
However, the utilization rate of the silk membrane structure in the conventional membrane oxygenator is not high, and mainly because of poor blood diversion and diffusion efficiency, blood is easy to accumulate at a certain position in the membrane oxygenator and only flows through a certain position of the silk membrane structure, and blood cannot flow through other positions of the silk membrane structure.
Disclosure of Invention
In view of the shortcomings in the prior art, the present invention aims to provide a spiral diversion integrated membrane oxygenator, which comprises: a lower cover having an air outlet pipe; the oxygenation part is arranged on the lower cover and comprises a mandrel structure, an oxygenation shell and an oxygenation silk membrane structure arranged between the mandrel structure and the oxygenation shell, wherein the oxygenation shell is provided with a blood outlet tube, and the blood outlet tube is close to the lower cover; the upper cover is arranged on the oxygenation part and is provided with an oxygen inlet pipe and an oxygen inlet pipe, and the oxygen inlet pipe and the air outlet pipe are communicated with the space between the mandrel structure and the oxygenation shell; the central spindle structure comprises a central spindle body and an annular guide plate, wherein the central spindle body is provided with a first end part and a second end part connected with the first end part, a blood channel is arranged between the first end part and an upper cover, the annular guide plate is sleeved on the central spindle body and is provided with at least one blood through hole and at least one spiral guide groove which are annularly arranged, the at least one blood through hole of the annular guide plate corresponds to the first end part of the central spindle body, and the at least one spiral guide groove of the annular guide plate is arranged on the outer surface of the annular guide plate and is positioned on one side of the at least one blood through hole of the annular guide plate.
Compared with the prior art, the method has the following technical effects:
the dabber structure of this application has annular guide plate, and annular guide plate is through the guide structure guide blood flow that has spiral guiding gutter to do the reposition of redundant personnel to blood, increase the diffusion area of blood, increase the area of contact of blood and silk membrane structure, effectively promote the utilization ratio of silk membrane structure, promote the oxygenation efficiency of diaphragm type oxygenator simultaneously.
Drawings
Fig. 1 is a perspective view of a spiral-flow-guided integrated membrane oxygenator according to a first embodiment of the present application.
Fig. 2 is an assembled view of a spiral-flow-guided integrated membrane oxygenator according to a first embodiment of the present application.
Fig. 3 is a cross-sectional view of a spiral-flow-guided integrated membrane oxygenator according to a first embodiment of the present application.
Fig. 4 is an assembly view of a spiral-flow-guided integrated membrane oxygenator according to a second embodiment of the present application.
Fig. 5 is a schematic view of an annular separator according to a third embodiment of the present application.
Fig. 6 is a cross-sectional view of a spiral-flow-guided integrated membrane oxygenator according to a fourth embodiment of the present application.
Fig. 7 is a schematic view of an intermediate annular separator according to a fifth embodiment of the present application.
Fig. 8 is a schematic view of an outer annular separator according to a fifth embodiment of the present application.
Fig. 9 is a schematic view of a silk film structure according to a sixth embodiment of the present application.
Detailed Description
Various embodiments of the present application are disclosed in the following figures, in which numerous practical details are set forth in the following description for purposes of clarity. However, it should be understood that these practical details are not to be taken as limiting the present application. That is, in some embodiments of the present application, these practical details are unnecessary. Moreover, for the purpose of simplifying the drawings, some conventional structures and components are shown in the drawings in a simplified schematic manner.
The terms "first," "second," and the like, as used herein, do not denote a particular order or sequence, nor are they intended to limit the application, but rather are merely used to distinguish one element or operation from another in the same technical term.
Referring to fig. 1, 2 and 3, a perspective view, an assembled view and a sectional view of a spiral guide integrated membrane oxygenator 1 according to a first embodiment of the present application are shown; as shown in the drawing, the present embodiment provides a spiral-flow-guide integrated membrane oxygenator 1, and the spiral-flow-guide integrated membrane oxygenator 1 includes a lower cover 10, an oxygenation portion 11, and an upper cover 12, wherein the oxygenation portion 11 is disposed between the lower cover 10 and the upper cover 12. The lower cover 10 includes a lower cover housing 101, a first lower annular support piece 102a, a second lower annular support piece 102b, an air outlet pipe 103, and an air inlet pipe 104, and the lower cover housing 101 has a lower surface 1011 and a lower annular side wall 1012 surrounding the lower surface 1011. The first lower annular supporting piece 102a and the second lower annular supporting piece 102b are disposed on the lower surface 1011 of the lower cover housing 101, the second lower annular supporting piece 102b is located outside the first lower annular supporting piece 102a and in the lower annular side wall 1012, the diameter of the first lower annular supporting piece 102a is smaller than that of the second lower annular supporting piece 102b, and the center of the first lower annular supporting piece 102a, the center of the second lower annular supporting piece 102b and the center of the lower cover 10 are located on the same line, that is, the first lower annular supporting piece 102a and the second lower annular supporting piece 102b are concentrically arranged in the lower cover housing 101. The air outlet pipe 103 is provided on the lower surface 1011 of the lower cover case 101 and communicates with the space between the second lower annular supporting piece 102b and the lower annular side wall 1012. The water inlet pipe 104 is disposed on the lower annular sidewall 1012 and penetrates through the lower annular sidewall 1012 and the second lower annular supporting piece 102b, and the water inlet pipe 104 is communicated with the space between the second lower annular supporting piece 102b and the first lower annular supporting piece 102a.
The oxygenation unit 11 includes a mandrel structure 110, an annular partition 111, an oxygenation housing 112, a lower blocking structure 113, a temperature-changing wire film structure 114, an oxygenation wire film structure 115, and an upper blocking structure 116, where the mandrel structure 110 is disposed on the first lower annular supporting sheet 102a and is located in the first lower annular supporting sheet 102a. The annular spacer 111 is disposed on the second lower annular support plate 102b and is located outside of the mandrel structure 110. The oxygenation housing 112 is disposed on the lower annular sidewall 1012 of the lower cover housing 101, and has a blood outlet tube 1121 and a circulation exhaust tube 1122, wherein the blood outlet tube 1121 is close to the lower cover 10, the circulation exhaust tube 1122 is located above the blood outlet tube 1121 and is far from the lower cover 10, and the blood outlet tube 1121 and the circulation exhaust tube 1122 are communicated with the space between the mandrel structure 110 and the oxygenation housing 112. The lower blocking structure 113 is disposed on the mandrel structure 110 and covers the lower cover 10, and is located between the mandrel structure 110 and the oxygenation housing 112. The temperature-changing wire film structure 114 is arranged on the mandrel structure 110 in a penetrating manner, is arranged on the lower blocking structure 113 and is positioned between the mandrel structure 110 and the annular partition 111, so that a temperature-changing area is formed between the mandrel structure 110 and the annular partition 111. The oxidized fiber membrane structure 115 is disposed through the mandrel structure 110 and on the lower blocking structure 113 and between the annular partition 111 and the oxidized shell 112, such that an oxidized area is formed between the annular partition 111 and the oxidized shell 112. The upper blocking structure 116 is disposed on the mandrel structure 110, on the temperature-changing wire film structure 114 and the oxidized wire film structure 115, and between the mandrel structure 110 and the oxidized shell 112.
Mandrel structure 110 of this embodiment includes a mandrel body 1101 and an annular deflector 1102, mandrel body 1101 having a first end 1101a and a second end 1101b connected to first end 1101a, the second end 1101b having an outer diameter greater than the outer diameter of first end 1101a, second end 1101b being disposed within first lower annular support sheet 102a. Annular baffle 1102 extends through mandrel body 1101 and is disposed on first lower annular support tab 102a of lower cover 10. The annular deflector 1102 has a plurality of blood ports 11023 and a plurality of spiral guide grooves 11022, wherein the plurality of blood ports 11023 correspond to the first end 1101a of the mandrel 1101, and the plurality of guide grooves 11022 are arranged on the outer surface of the annular deflector 1102 at intervals, are positioned on one side of the plurality of blood ports 11023, and correspond to the second end 1101b of the mandrel 1101. The horizontal circumferential length from one end of each spiral flow guide groove 11022 to the other end thereof is longer than the half circumference of the annular flow guide plate 1102, and the vertical distance between one end of each spiral flow guide groove 11022 and the other end thereof is between one half of the height of the annular flow guide plate 1102 and two thirds of the height of the annular flow guide plate 1102.
However, first end 1101a of mandrel body 1101 has a flow guiding arcuate surface 11011, and one end of each spiral flow guiding groove 11022 is connected to flow guiding arcuate surface 11011, in other words, a plurality of spiral flow guiding grooves 11022 are located at one side of first end 1101a of mandrel body 1101 and correspond to second end 1101b of mandrel body 1101. Flow-guiding arcuate surface 11011 of mandrel body 1101 can buffer the flow rate of blood and guide the smooth flow of blood in the blood channel without blood accumulating at first end 1101a of mandrel body 1101. However, the plurality of spiral guide grooves 11022 are directly connected to the guide arc surface 11011, and the guide arc surface 11011 can directly guide blood to the plurality of spiral guide grooves 11022, so that the blood can rapidly fill the plurality of spiral guide grooves 11022.
The annular partition 111 of the present embodiment has a plurality of blood ports 1111 arranged in an annular shape, the plurality of blood ports 1111 serving as a flow guide structure, and the plurality of blood ports 1111 being close to the lower cover 10. The annular partition 111 of the present embodiment mainly achieves the supporting function, and extends the blood diffusion path, increases the contact area and diffusion area between the blood and the temperature change wire film structure 114 and the oxidized wire film structure 115, and further increases the utilization rate of the temperature change wire film structure 114 and the oxidized wire film structure 115.
The upper cover 12 includes an upper cover housing 121, a first upper annular supporting piece 122a, a second upper annular supporting piece 122b, a blood inlet tube 124, an oxygen inlet tube 125 and a water outlet tube 126, and the upper cover housing 121 has an upper surface 1211 and an upper annular sidewall 1212 encircling the upper surface 1211. The first upper annular supporting piece 122a and the second upper annular supporting piece 122b are disposed on the upper surface 1211 of the upper cover housing 121, the second upper annular supporting piece 122b is located outside the first upper annular supporting piece 122a, the first upper annular supporting piece 122a and the second upper annular supporting piece 122b are located in the upper annular side wall 1212, and the centers of the first upper annular supporting piece 122a and the second upper annular supporting piece 122b and the center of the upper cover housing 121 are located on the same line. The blood inlet tube 124 is disposed on the upper annular sidewall 1212 of the upper cover housing 121, penetrates through the upper annular sidewall 1212, the second upper annular supporting plate 122b and the first upper annular supporting plate 122a, and is connected to the space in the first upper annular supporting plate 122 a. The oxygen inlet pipe 125 is disposed on the upper annular sidewall 1212 of the upper cover housing 121 and penetrates the upper annular sidewall 1212, and the oxygen inlet pipe 125 communicates with the space between the upper annular sidewall 1212 and the second upper annular supporting plate 122 b. The water outlet pipe 126 is disposed on the upper annular sidewall 1212 of the upper cover housing 121, penetrates through the upper annular sidewall 1212 and the second upper annular supporting plate 122b, and communicates with a space between the first upper annular supporting plate 122a and the second upper annular supporting plate 122 b.
When the upper cover 12 is disposed on the oxygenation portion 11, the first upper annular supporting piece 122a and the second upper annular supporting piece 122b are concentrically arranged in the upper cover housing 121, the first lower annular supporting piece 102a corresponds to the first upper annular supporting piece 122a, the second lower annular supporting piece 102b corresponds to the second upper annular supporting piece 122b, the upper annular sidewall 1212 of the upper cover housing 121 corresponds to the lower annular sidewall 1012 of the lower cover housing 101, and the upper annular sidewall 1212 of the upper cover housing 121, the second upper annular supporting piece 122b and the first upper annular supporting piece 122a are respectively engaged with the oxygenation housing 112 of the oxygenation portion 11, the annular partition 111 and the annular deflector 1102 of the mandrel structure 110. The centers of the lower cap 10, the oxidized part 11 and the upper cap 12 are located on the same line.
The space between the first lower annular supporting piece 102a and the second lower annular supporting piece 102b of the lower cover housing 101 and the space between the first upper annular supporting piece 122a and the second upper annular supporting piece 122b of the upper cover housing 121 correspond to the space between the mandrel structure 110 and the annular partition 111, and the water inlet pipe 104 of the lower cover 10 and the water outlet pipe 126 of the upper cover 12 are communicated with the space between the mandrel structure 110 and the annular partition 111. The space between the lower annular sidewall 1012 of the lower cover housing 101 and the second lower annular supporting piece 102b and the space between the upper annular sidewall 1212 of the upper cover housing 121 and the second upper annular supporting piece 122b correspond to the space between the mandrel structure 110 and the oxygenation housing 112, and the oxygen inlet pipe 125 of the upper cover 12 and the air outlet pipe 103 of the lower cover 10 communicate with the space between the mandrel structure 110 and the oxygenation housing 112.
In use of the spiral-flow-guide integrated-membrane oxygenator 1 of the present embodiment, blood from the extracorporeal blood circuit device enters the blood passageway of the mandrel body 1101 from the blood inlet 124 of the spiral-flow-guide integrated-membrane oxygenator 1. When blood flows in from the plurality of blood ports 11023, the blood flows down from top to bottom along the outer surface of the annular baffle 1102, the blood rapidly flows into the plurality of spiral guide grooves 11022 communicated with the plurality of blood ports 11023, and then the blood flows from the plurality of spiral guide grooves 11022 of the annular baffle 1102 to the temperature change wire film structure 114, so that the contact area and the diffusion area of the blood and the temperature change wire film structure 114 are increased, the utilization rate of the temperature change wire film structure 114 is increased, and the pressure of the spiral guide integrated film oxygenator 1 is reduced, in other words, the annular baffle 1102 of the embodiment achieves the above effect through the guide structure with the plurality of spiral guide grooves 11022.
When blood enters the temperature change wire membrane structure 114, water with a modulated temperature is simultaneously introduced from the water inlet pipe 104 of the lower cover 10, and the water with the modulated temperature flows from one end of the temperature change wire membrane structure 114 close to the lower cover 10 to the other end of the temperature change wire membrane structure 114 close to the upper cover 10, and the temperature of the blood diffused in the temperature change wire membrane structure 114 is adjusted by the temperature of the water. The blood having diffused into the temperature-changing yarn membrane structure 114 and having been subjected to temperature adjustment flows toward the lower cover 10, flows into the plurality of blood ports 1111 of the annular partition 111, and diffuses toward the oxidized yarn membrane structure 115.
When blood flows into the oxygenation filament membrane structure 115, oxygen is fed from the oxygen inlet tube 125 to the space between the second upper annular support piece 122b and the oxygenation housing 112, in other words, the oxygen in the oxygen inlet tube 125 is oxygenated with the blood in the oxygenation filament membrane structure 115 to replace carbon dioxide in the blood, carbon dioxide is generated during the oxygenation process, and the carbon dioxide sinks to the lower cover 10 and is discharged from the air outlet tube 103 of the lower cover 10. Finally, oxygenated blood is expelled from the blood tube 1121 of the oxygenation housing 112.
The temperature-changing filament membrane structure 114 and the oxidized filament membrane structure 115 each include a plurality of hollow fiber layers, the hollow fiber tube of each hollow fiber layer has a circular, square or oval cross section, and the gas generated when the hollow fiber of each layer is broken is discharged from the circulation exhaust pipe 1122 of the oxidized shell 112. The lower barrier structure 113 and the upper barrier structure 116 block blood located within the temperature change wire membrane structure 114 and the oxygenation wire membrane structure 115 from moving toward the lower cover 10 or the upper cover 12.
Please refer to fig. 4, which is an assembled view of the spiral guide integrated membrane oxygenator 1 according to the second embodiment of the present application; as shown in the drawing, the spiral-flow-guide integrated-type membrane oxygenator 1 of the present embodiment is different from the spiral-flow-guide integrated-type membrane oxygenator of the above embodiment in that the spiral-flow-guide integrated-type membrane oxygenator 1 of the present embodiment omits the installation of the temperature change region, that is, omits the installation of the water inlet pipe of the lower cover 11, the second lower annular supporting piece of the lower cover 11, the annular partition plate, the second upper annular supporting piece of the upper cover 12, and the water outlet pipe of the upper cover 12. The oxidized fiber membrane structure 115 is directly disposed between the mandrel structure 110 and the oxidized shell 112, and the air outlet pipe of the lower cover 11 and the air inlet pipe 125 of the upper cover 12 are respectively communicated with the space between the mandrel structure 110 and the oxidized shell 112, so that the space between the mandrel structure 110 and the oxidized shell 112 forms an oxidized area.
Referring to fig. 5, a schematic view of an annular partition 111 according to a third embodiment of the present application is shown; as shown in the figure, in the first embodiment, the outer surface of the annular partition 111 has a flow guiding structure, which is a plurality of spiral flow guiding grooves 1112 arranged at intervals, and the plurality of spiral flow guiding grooves 1112 of the annular partition 111 are located at one side of the plurality of blood ports 1111 of the annular partition 111, and even one end of each spiral flow guiding groove 1112 is communicated with the corresponding blood port 1111. The horizontal circumferential length of one end and the other end of each spiral guide groove 1112 is greater than the semicircular circumference of the annular partition 111, in other words, each spiral guide groove 1112 surrounds more than half a turn of the annular partition 111; the vertical distance between the two ends of each spiral guide groove 1112 is between the height of one-half of the annular partition 111 and the height of two-thirds of the annular partition 111. The plurality of spiral guide grooves 1112 of the annular partition 111 guide the blood to flow and are diffused to fill the plurality of spiral guide grooves 1112, so that the diffusion area of the blood is increased to be fully contacted with the oxygenation filament membrane structure, and the contact area between the oxygenation filament membrane structure and the blood and the utilization rate of the oxygenation filament membrane structure are increased. However, one end of each spiral guide groove 1112 is connected to the corresponding blood port 1111, so that blood flows from the plurality of blood ports 1111 and can flow into the plurality of spiral guide grooves 1112 in real time, and the blood fills the whole spiral guide grooves 1112 rapidly. The circumferential direction of the plurality of spiral guide grooves of the mandrel structure of the present embodiment is opposite to the circumferential direction of the plurality of spiral guide grooves 1112 of the adjacent annular partition 111.
Referring to fig. 6, a cross-sectional view of a spiral guide integrated membrane oxygenator 1 according to a fourth embodiment of the present disclosure; as shown in the figure, the number of the annular spacers in this embodiment is two, the two annular spacers are hereinafter referred to as an annular spacer 111a and an annular spacer 111b, the diameter of the annular spacer 111a is smaller than that of the annular spacer 111b, the annular spacer 111a is fixed by the corresponding second lower annular support piece 102b and second upper annular support piece 122b, the annular spacer 111b is fixed by the lower annular side wall 1012 of the lower cover housing 101 and the upper annular side wall 1212 of the upper cover housing 121, and the annular spacer 111b surrounds the oxidized wire film structure. The middle annular partition plate 111a and the outer annular partition plate 111b of the present embodiment each have a flow guide structure formed of a plurality of blood ports 1111 arranged in an annular shape, and the positions of the plurality of blood ports 1111 of the middle annular partition plate 111a are opposite to the positions of the plurality of blood ports 1111 of the outer annular partition plate 111b, the plurality of blood ports 1111 of the middle annular partition plate 111a of the present embodiment are close to the lower cover 10, and the plurality of blood ports 1111 of the outer annular partition plate 111b are close to the upper cover 12. The spiral flow-guiding integrated membrane oxygenator 1 of the embodiment increases the number of annular partition plates, increases the diffusion distance between blood and the temperature-changing wire membrane structures and the oxygenation wire membrane structures, increases the contact area and the diffusion area between the blood and the temperature-changing wire membrane structures and the oxygenation wire membrane structures, and improves the utilization rate of the temperature-changing wire membrane structures and the oxygenation wire membrane structures. In addition, the plurality of blood ports 1111 of the outer annular partition 111b are far from the blood vessel 1121, and the blood is prevented from directly flowing into the blood vessel 1121 from the plurality of blood ports 1111 of the outer annular partition 111b, thereby further improving the utilization ratio of the temperature change wire film structure and the oxidized wire film structure. The surface of the outer annular partition 111b of the present embodiment is further provided with a filter for removing blood particles and gas micro-emboli.
Referring to fig. 7 and 8, a schematic view of an annular partition 111a and a schematic view of an annular partition 111b according to a fifth embodiment of the present disclosure are shown; as shown in the figure, according to the fourth embodiment, the middle annular partition 111a and the outer annular partition 111b of the present embodiment have the plurality of flow guide perforations 1113 uniformly distributed, and the middle annular partition 111a and the outer annular partition 111b of the present embodiment have the plurality of flow guide perforations 1113, respectively, so that the arrangement of the plurality of blood ports of the middle annular partition 111a and the outer annular partition 111b can be omitted. The apertures of the plurality of flow guiding perforations 1113 of the outer annular partition 111b are smaller than the apertures of the plurality of flow guiding perforations 1113 of the middle annular partition 111a, and the apertures of the plurality of flow guiding perforations 1113 of the middle annular partition 111a and the outer annular partition 111b and the plurality of flow guiding perforations of the annular flow guiding plates are larger than 3mm. Of course, the outer annular partition 111b may be omitted, or the outer annular partition 111b may be identical to the outer annular partition of the fourth embodiment, and will not be described again.
The plurality of flow-guiding perforations 1113 of the middle annular partition 111a and the outer annular partition 111b mainly guide the flow of blood and split the flow of blood, and the flow rate and flow rate of blood in the single flow-guiding perforation 1113 are reduced, and the blood flowing out from each flow-guiding perforation 1113 can be gently contacted with the oxidized fiber membrane structure. However, each of the flow guiding holes 1113 of the middle annular partition 111a of the present embodiment is a square hole, so that the blood is collected in the flow guiding holes 1113 of the middle annular partition 111a, and the flow guiding holes 1113 of the square holes can buffer the blood. The position of the outer annular partition 111b of the blood vessel 1121 corresponding to the oxygenation casing 112 is not provided with the diversion perforation 1113, that is, the shortest distance between the center of the diversion perforation 1113 of the outer annular partition 111b adjacent to the blood vessel 1121 and the center of the blood vessel 1121 is greater than 5mm, so that blood is prevented from directly flowing out of the diversion perforation 1113 adjacent to the blood vessel 1121, blood can flow out of the diversion perforation 1113 far from the blood vessel 1121, the utilization rate of the oxygenation wire membrane structure is improved, and the blood can be uniformly diffused.
The inner surfaces of the middle annular partition plate 111a and the outer annular partition plate 111b of the present embodiment are further provided with a plurality of spiral diversion trenches arranged at intervals, and the plurality of diversion perforations 1113 of the middle annular partition plate 111a and the outer annular partition plate 111b are respectively positioned in the plurality of spiral diversion trenches of the middle annular partition plate 111a and the outer annular partition plate 111 b. Each spiral guide groove surrounds the inner surface of the middle annular partition 111a or the outer annular partition 111b by more than half a circle, in other words, the horizontal circumferential length from one end to the other end of each spiral guide groove is longer than the half circumference of the middle annular partition 111a or the outer annular partition 111b, and the vertical distance from one end to the other end of each spiral guide groove is between one half of the height of the middle annular partition 111a or the outer annular partition 111b and two thirds of the height of the middle annular partition 111a or the outer annular partition 111 b.
Please refer to fig. 9, which is a schematic diagram of a silk film structure 13 according to a sixth embodiment of the present application; as shown in the drawing, the filament membrane structure 13 of the present embodiment can be applied to the temperature-changing filament membrane structure and the oxidized filament membrane structure of the above embodiment, which includes a plurality of hollow fiber layers 131, each hollow fiber layer 131 having a plurality of hollow fiber tubes 1311, the plurality of hollow fiber tubes 1311 being inclined at an angle with respect to the vertical plane, the inclination direction of the plurality of hollow fiber tubes 1311 of each hollow fiber layer 131 being different from the inclination direction of the plurality of hollow fiber tubes 1311 of the adjacent hollow fiber layer 131, in other words, in which the plurality of hollow fiber tubes 1311 of one hollow fiber layer 131 and the plurality of hollow fiber tubes 1311 of the other hollow fiber layer 131 intersect each other, the hollow fiber tube 1311 of each hollow fiber layer 131 being inclined at an angle of 15 degrees with respect to the vertical plane. The hollow fiber tube 1311 of the hollow fiber layer 131 of each layer has a circular, square or oval cross section, so that the blood pre-charge amount can be reduced. When blood flows into the space between two adjacent hollow fiber layers 131 of the silk membrane structure 13, the blood can be split into thinner blood membranes, the contact area between the blood and the oxygen is increased, and the oxygenation efficiency of the blood and the oxygen is improved.
The number of the annular baffle, the annular partition, the middle annular partition, the flow guide perforation of the outer annular partition, the blood port or the spiral flow guide groove in the above embodiment is one. In addition, the shortest distance between the center of the flow-guiding perforation of the middle annular barrier 111 adjacent to the outlet vessel and the center of the outlet vessel is greater than 5mm.
To sum up, the application provides a spiral water conservancy diversion integrated film oxygenator, and dabber structure has annular guide plate, and annular guide plate is through the water conservancy diversion structure guide blood flow that has spiral guiding gutter, increases the diffusion area of blood, increases the area of contact of blood and silk membrane structure, effectively promotes the utilization ratio of silk membrane structure, promotes the oxygenation efficiency of film oxygenator simultaneously. The spiral guide integrated membrane oxygenator can be provided with at least one annular partition plate, the annular partition plate can support the spiral guide integrated membrane oxygenator, and meanwhile, the spiral guide integrated membrane oxygenator is provided with a guide structure which has the same effect as that of the annular guide plate. The adjacent two hollow fiber layers of the silk membrane structure have small spacing, and can split the blood, so that the blood forms a thinner blood membrane, and the oxygenation efficiency of the blood and oxygen is improved. The hollow fiber tube of each hollow fiber layer has an elliptical cross section, so that the amount of blood to be pre-filled can be reduced.
The foregoing is merely an embodiment of the present application and is not intended to limit the present application. Various modifications and changes may be made to the present application by those skilled in the art. Any modifications, equivalent substitutions, improvements, or the like, which are within the spirit and principles of the present application, are intended to be included within the scope of the claims of the present application.
Claims (10)
1. A spiral-flow-directing integrated membrane oxygenator, comprising:
a lower cover having an air outlet pipe;
the oxygenation part is arranged on the lower cover and comprises a mandrel structure, an oxygenation shell and an oxygenation silk membrane structure arranged between the mandrel structure and the oxygenation shell, wherein the oxygenation shell is provided with a blood outlet tube, and the blood outlet tube is close to the lower cover; and
the upper cover is arranged on the oxygenation part and is provided with an oxygen inlet pipe and an oxygen inlet pipe, and the oxygen inlet pipe and the air outlet pipe are communicated with a space between the mandrel structure and the oxygenation shell;
the central spindle structure comprises a central spindle body and an annular guide plate, wherein the central spindle body is provided with a first end and a second end connected with the first end, the outer diameter of the second end is larger than that of the first end, the first end is provided with a guide cambered surface, a blood channel is arranged between the first end and an upper cover, the annular guide plate is sleeved on the central spindle body and is provided with at least one blood through hole and at least one spiral guide groove which are annularly arranged, the at least one blood through hole of the annular guide plate corresponds to the first end of the central spindle body, the at least one spiral guide groove of the annular guide plate is arranged on the outer surface of the annular guide plate and is positioned on one side of the at least one blood through hole of the annular guide plate and corresponds to the second end of the central spindle body, the plurality of spiral guide grooves are directly connected with the guide cambered surface, and the horizontal circumference length from one end of each spiral guide groove to the other end of each spiral guide groove is larger than the circumference of the semicircle of the annular guide plate.
2. The spiral guide integrated membrane oxygenator according to claim 1, further comprising at least one annular partition plate, wherein the at least one annular partition plate is arranged between the mandrel structure and the oxygenation shell, the lower cover is provided with a water inlet pipe, the upper cover is provided with a water outlet pipe, and the water inlet pipe and the water outlet pipe are communicated with a space between the annular partition plate close to the mandrel structure and the mandrel structure; the oxygen inlet pipe and the air outlet pipe are communicated with a space between the annular partition plate close to the mandrel structure and the oxygenation shell; and a variable-temperature wire film structure is arranged between the annular partition plate close to the mandrel structure and the mandrel structure, and an oxygenation wire film structure is arranged between the annular partition plate close to the mandrel structure and the oxygenation shell.
3. The spiral guide integrated membrane oxygenator according to claim 2, wherein the temperature changing wire membrane structure and the oxygenation wire membrane structure respectively comprise a plurality of hollow fiber layers, each hollow fiber layer is provided with a plurality of hollow fiber tubes, and the cross section of each hollow fiber tube is circular, square or elliptical.
4. The spiral-flow-directing integrated-membrane oxygenator as claimed in claim 1, wherein each annular partition includes at least one blood port and at least one spiral-flow-directing groove arranged in an annular manner, the at least one blood port of the annular partition adjacent to the mandrel structure is adjacent to the lower cover, and the at least one spiral-flow-directing groove of each annular partition is disposed on an outer surface of the corresponding annular partition and is located on one side of the at least one blood port of the corresponding annular partition.
5. The spiral-flow-directing integrated membrane oxygenator of claim 1 wherein each annular barrier has at least one flow-directing perforation, the at least one flow-directing perforation of each annular barrier being distributed over the corresponding annular barrier.
6. The spiral-guide integrated membrane oxygenator according to claim 5 wherein each annular partition further comprises at least one spiral guide groove, wherein at least one spiral guide groove of each annular partition is disposed on an inner surface of the corresponding annular partition, and wherein at least one guide perforation of each annular partition is located within at least one spiral guide groove of the corresponding annular partition.
7. The spiral membrane integrated-type membrane oxygenator of claim 1, wherein the at least one annular baffle comprises a middle annular baffle and an outer annular baffle, the outer annular baffle is disposed on the outer side of the middle annular baffle, the outer annular baffle is adjacent to the oxygenation shell, the middle annular baffle and the outer annular baffle are respectively provided with at least one flow guiding perforation, the at least one flow guiding perforation of the middle annular baffle is distributed on the middle annular baffle, and the at least one flow guiding perforation of the outer annular baffle is distributed on the outer annular baffle.
8. The spiral-flow-directed integrated membrane oxygenator of claim 7 wherein a surface of the outer annular barrier is provided with a filter for removing blood particles and gaseous micro-emboli.
9. The spiral membrane oxygenator according to claim 7, wherein the middle annular partition plate and the outer annular partition plate further comprise at least one spiral diversion trench, the at least one spiral diversion trench of the middle annular partition plate is arranged on the inner surface of the middle annular partition plate at intervals, the at least one spiral diversion trench of the outer annular partition plate is arranged on the inner surface of the outer annular partition plate at intervals, and the at least one diversion perforation of the middle annular partition plate and the at least one spiral diversion trench of the outer annular partition plate are respectively located in the middle annular partition plate and the at least one spiral diversion trench of the outer annular partition plate.
10. The spiral-flow-directed integrated-membrane oxygenator of claim 7 wherein a shortest distance between a center of the middle annular barrier and/or the at least one flow-directing perforation of the outer annular barrier adjacent the outflow vessel and a center of the blood vessel is greater than 5mm.
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| CN201710817398.1A CN107432960B (en) | 2017-09-12 | 2017-09-12 | Spiral diversion integrated film type oxygenator |
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| CN201710817398.1A CN107432960B (en) | 2017-09-12 | 2017-09-12 | Spiral diversion integrated film type oxygenator |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111317876B (en) * | 2018-12-26 | 2022-11-04 | 东莞科威医疗器械有限公司 | Integrated ECMO (external life support) equipment |
| CN111298287B (en) * | 2018-12-26 | 2023-08-25 | 东莞科威医疗器械有限公司 | Bionic ECMO equipment for external life support |
| CN113599605B (en) * | 2021-07-29 | 2024-02-20 | 深圳汉诺医疗科技有限公司 | Membrane type oxygenator |
| CN115501407B (en) * | 2022-09-28 | 2023-07-28 | 江苏赛腾医疗科技有限公司 | Membrane oxygenator blood storage tank |
| CN115607759B (en) * | 2022-10-31 | 2023-04-28 | 北京航空航天大学 | Blood oxygenator |
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