CN107384669A - Grape wine with nourishing function and preparation method thereof - Google Patents
Grape wine with nourishing function and preparation method thereof Download PDFInfo
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- CN107384669A CN107384669A CN201710682433.3A CN201710682433A CN107384669A CN 107384669 A CN107384669 A CN 107384669A CN 201710682433 A CN201710682433 A CN 201710682433A CN 107384669 A CN107384669 A CN 107384669A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G1/00—Preparation of wine or sparkling wine
- C12G1/02—Preparation of must from grapes; Must treatment and fermentation
- C12G1/0203—Preparation of must from grapes; Must treatment and fermentation by microbiological or enzymatic treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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Abstract
The invention discloses a kind of grape wine with nourishing function and preparation method thereof, it is related to brewing technical field.This grape wine with nourishing function is using grape, the Radix Astragali, sea-buckthorn and ganoderma lucidum as raw material, preparation method is first to extract Astragaloside IV, Hippophate flavone, GL-B and ganoderic acid respectively, and brew grape wine, then Astragaloside IV solution, ganoderma active solution, Hippophate flavone solution are added in obtained grape wine, hybrid modulation produces.The present invention is solved because adding a large amount of Chinese herbal medicines, not only causes obtained grape wine to be mixed into the smell of a large amount of Chinese herbal medicines, also so that the problem of color of grape wine is doped with other colors.
Description
Technical field
The present invention relates to brewing technical field, especially a kind of grape wine with nourishing function and preparation method thereof.
Background technology
Grape wine is the alcoholic beverage led to fresh grape or grape juice through fermenting completely or partially.Known grape
The composition beneficial to human body contained in wine about just has 600 kinds.Thus the nutritive value of grape wine has also obtained widely recognizing
Can.Wherein, grape wine has certain tonic effect.The human body that contains in grape wine essential nutrient such as sugar, amino
Acid, vitamin, mineral matter, it can directly be absorbed by the body without advance digestion.Outstanding is to weakling, is often drunk
Appropriate grape wine, it is favourable to getting well.Aldehydes matter and Ao Li multielements in grape wine（OligoeLement）, have and do
The function of oxidant, the reactive oxygen occurred during body metabolism can be prevented（Ros）Injury to human body（Such as in cell
DNA and RNA injury）, these injuries are to cause some organ collpase's property diseases, such as cataract, and cardiovascular disease, artery are hard
Change, one of the factor of aging.Therefore, often drinking appropriate grape wine has effect that is anti-aging, prolonging life.
But only by grape wine equally come it is anti-aging, prolong life, its effect is too slow, so base of the people in grape wine
Many nourishing Chinese herbal medicines are added on plinth, such as application for a patent for invention " a kind of 201410512646.8 grape wine with nourishing function and its preparation
Method ", disclose with fresh grape, ginseng, fresh ginger, cordyceps sinensis, ganoderma lucidum, yeast, spontaneous fermentation system after white sugar and honey mixing
Obtain the scheme of the grape wine with nourishing function；Application for a patent for invention " 201410723371.2 a kind of grape wine with nourishing function and preparation method thereof ",
Disclose with grape, maca, Fructus Corni, jujube, rhodiola root, the fruit of Chinese wolfberry to prepare the scheme of grape wine.These grape wine because
A large amount of Chinese herbal medicines are added, not only cause obtained grape wine to be mixed into the smell of a large amount of Chinese herbal medicines, also cause the face of grape wine
Color is doped with other colors.
The content of the invention
A kind of grape wine with nourishing function provided by the present invention and preparation method thereof, it can be solved because adding a large amount of medium-height grass
Medicine, not only cause obtained grape wine to be mixed into the smell of a large amount of Chinese herbal medicines, also cause the color of grape wine to be doped with other face
The problem of color.
In order to solve the above problems, the technical solution adopted in the present invention is：This grape wine with nourishing function, including following weight
The raw material of part：90~95 parts of grape, 3~5 parts of the Radix Astragali, 2~5 parts of sea-buckthorn, 2~5 parts of ganoderma lucidum.
The preparation method of this grape wine with nourishing function, comprises the following steps：
（1）The processing of the Radix Astragali：The Radix Astragali is crushed, extracts Astragaloside IV, then the Astragaloside IV extracted is dissolved in 95% food
With alcohol, Astragaloside IV solution for standby is obtained；
（2）The processing of ganoderma lucidum：Ganoderma lucidum is crushed, extracts GL-B and ganoderic acid, is then dissolved in 95% edible alcohol,
Obtain ganoderma active solution for standby；
（3）The processing of sea-buckthorn：Hippophate flavone is extracted, 95% edible alcohol is then dissolved in, it is standby to obtain Hippophate flavone solution
With；
（4）Wine brewing：By grape extraction juice, cold fermentation, grape wine is made in constant temperature ageing；
（5）Rectification：By step（1）、（2）With（3）Astragaloside IV solution, ganoderma active solution, the Hippophate flavone solution of gained add
Enter to step（4）In obtained grape wine, hybrid modulation produces.
By adopting the above-described technical solution, the present invention has the advantages that compared with prior art：
1st, grape wine with nourishing function produced by the present invention maintains the aromatic taste of pure grape wine and pure color, without taste of traditional Chinese medicine
With the color mixed.
2nd, Astragaloside IV is as one of main active component in the Radix Astragali, and ASI (Astragaloside IV) is again
Claim Astragaloside IV, be that a kind of polarity of saponin component is larger, belong to natural flavonoid compound, its sterling is that white needles are brilliant
Body or pale yellow powder, bitter is warm-natured, molecular formula C41H68O14, molecular weight:784 .9702, molten point is 284~286 DEG C, several
Cold water is not dissolved in, DMSO can be dissolved in, be slightly dissolved in methanol, is practically insoluble in ethyl acetate, acetone and water, ethanol
Dissolve by heating, separated out after cold.It can improve cardio-pulmonary function, strengthen cardiac contractile force, expand blood vessel, reduce blood pressure, and improve skin
Blood circulation and nutrition condition；And liver can be protected, prevent liver glycogen from reducing, to CAH, there is good action.It is yellow
Stilbene also has inducement interferon and transfers the effect of body's immunity, can suppress virus breeding and tumour growth.Strengthen immunity,
Increase energy, it is antifatigue, make mutation, liver protection, suppress the effect of osteoclast.
3rd, plant sea-buckthorn is Elaeangnaceae Hippophne, is a kind of fallen leaves property shrub, and its characteristic is drought-enduring, anti-blown sand, can be with
Survived on wetland with saline-alkaline, therefore be widely used in water and soil conservation.The country is distributed in the ground such as North China, northwest, southwest.Modern times grind
Study carefully proof, the active ingredient Hippophate flavone in sea-buckthorn, mainly containing Isorhamnetin (isorhamnetin), Isorhamnetin -3-B-D-
Glycoside (isorhamnetin-3-B-D-glucoside), Isorhamnetin -3-B- rutinosides (isorhamnetin-3-
B-rutinoside), the low sugar glucoside (oligosides) of Mongolian oak chitin and Kaempferol.There is extensive pharmacology to cardio-cerebrovascular
Effect：First, Hippophate flavone can reduce blood fat, cholesterol, beta lipoprotein, improve hemorheological property, expand tube chamber, and increase is coronal
Blood flow volume, the frequency and degree of allevating angina pectoris breaking-out;Secondly, promote blood vessel endothelium to produce prostacyclin, suppress blood
Platelet is assembled, and reduces the scope of miocardial infarction;Finally, flavones can improve lecithin courage with alcohol acyl group as internal antioxidant
The activity of transferase, the low density cholesterol in blood is dissolved into molecule, then puts absorption of human body, so as to prevent because of courage
Sterol deposits caused artery sclerosis on vascular wall, prevents the various cardiovascular and cerebrovascular diseases as caused by artery sclerosis.
Embodiment
Below in conjunction with specific embodiment, the invention will be further described：
（One）This grape wine with nourishing function, raw material used are as follows：90~95kg of grape, the kg of the Radix Astragali 3~5, the kg of sea-buckthorn 2~5, spirit
The kg of sesame 2~5.
（Two）Preparation method, comprise the following steps：
（1）The processing of the Radix Astragali：The Radix Astragali be crushed into 20 mesh sieves, the Radix Astragali is equipped with 6 times of amounts by microwave field as assisted extraction condition
The ethanol water of 60% concentration, regulation pH value is 12, and Microwave Pretreatment certain time, Microwave Pretreatment are carried out in microwave field
It is divided into 5 progress, each microwave time 2min, microwave 2min again when being then rapidly cooled to below 20 DEG C in ice-water bath, 5 times
Immersion 8h after pretreatment, it is 12 to adjust pH value again, and microwave auxiliary reflux extraction is carried out in microwave field, and extraction power is
70W/g, 2min is extracted every time, extract 10 times；After separating decoction, the dregs of a decoction are carried out with refluxing extraction 20min again, merges extract solution,
Spray drying obtains Astragaloside IV extract, discards the dregs of a decoction.With 1:The Astragaloside IV ethanol extract that 1 volume ratio will extract
Be dissolved in 95% edible alcohol it is standby.
（2）The processing of ganoderma lucidum：Ganoderma lucidum be crushed into 20 mesh sieves, under the conditions of 15~100KHz of supersonic frequency, 40~90 DEG C,
50~100% ethanol for adding 5~50mL/g glossy ganoderma powders are solvent 10~90min of alcohol extracting, and filtering, filtrate is spray-dried to obtain spirit
Sesame triterpene extract, filter residue are used for the extraction of GL-B；Filter residue under the conditions of 35~70 DEG C, pH3.5~7.0, add 10~
The distilled water of 100mL/g glossy ganoderma powders, 0.5~4h of water extraction is digested under compound enzyme effect, enzyme deactivation, centrifuging and taking supernatant concentration is extremely
Volume is the 1/6~1/2 of supernatant volume, and 95% ethanol that volume is the volume of concentrate 3 is added into concentrate, stir,
12~24h is stood, centrifuging and taking precipitation spray drying obtains ganoderan extract.With 1:The ganoderma lucidum three that 1 volume ratio will obtain
The edible alcohol that terpene and ganoderan extract are dissolved in 95% is standby.
（3）The processing of sea-buckthorn：The water of gaza's 10 times of weight of spine medicinal material, 0.5h is soaked, decoct 1h, filtering, the dregs of a decoction add
The water of 8 times of weight of medicinal material, 1h is decocted, decoction filters out, and merges decoction liquor twice, and it is 1.05 to be concentrated into 60 DEG C of relative densities, adds second
Alcohol makes the percent by volume of alcohol content stir, stand up to 75%, and filtering, relative density is 1.25 when filtrate is concentrated into 65 DEG C, and
Ethanol is reclaimed, concentrate is obtained, is refined using macroreticular resin, eluent is collected, continues to concentrate, concentrate is dried, obtain husky
Spine chromocor extract.With 1:1 volume ratio is dissolved in 95% edible alcohol, obtains Hippophate flavone solution for standby.
（4）Wine brewing：By grape extraction juice, cold fermentation, grape wine is made in constant temperature ageing.
（5）Rectification：By step（1）、（2）With（3）Astragaloside IV solution, ganoderma active solution, the Hippophate flavone of gained are molten
Liquid is added to step（4）In obtained grape wine, hybrid modulation produces.
（Three）The composition of raw materials such as table 1 below that embodiment 1~9 uses：
Table 1
（Four）Clinical test：180 inferior health volunteers are selected, are randomly divided into 9 groups, every group of 20 people, every group is drunk implementation respectively
The grape wine with nourishing function of example 1 ~ 9,50 ~ 100ml is drunk daily, effect is just drunk behind 1 month and 3 months respectively it is returned
Visit, drinking effect includes the state of mind, face situation etc., wherein the good situation of the state of mind be the eyes are bright and piercing, sound it is loud and clear,
Have good memory, be swift in response, the preferable situation of the state of mind be binocular relatively have god, sound is louder and clearer, memory is preferable, react compared with
It hurry up, typically one's eyes are lustreless for the state of mind, sound is general, memory is general, reaction is general.Record such as table 2 below, table 3：
Table 2 drinks return visit situation of the grape wine with nourishing function of the present invention after 1 month
Table 3 drinks return visit situation of the grape wine with nourishing function of the present invention after 3 months
It can be seen that grape wine with nourishing function of the invention easily absorbs, tonic effect is good.
Claims (2)
1. a kind of grape wine with nourishing function, it is characterised in that include the raw material of following parts by weight：90~95 parts of grape, 3~5 parts of the Radix Astragali,
2~5 parts of sea-buckthorn, 2~5 parts of ganoderma lucidum.
A kind of 2. preparation method of grape wine with nourishing function, it is characterised in that：
Include the raw material of following parts by weight：90~95 parts of grape, 3~5 parts of the Radix Astragali, 2~5 parts of sea-buckthorn, 2~5 parts of ganoderma lucidum；
Comprise the following steps：
（1）The processing of the Radix Astragali：The Radix Astragali is crushed, extracts Astragaloside IV, then the Astragaloside IV extracted is dissolved in 95% food
With alcohol, Astragaloside IV solution for standby is obtained；
（2）The processing of ganoderma lucidum：Ganoderma lucidum is crushed, extracts GL-B and ganoderic acid, is then dissolved in 95% edible alcohol,
Obtain ganoderma active solution for standby；
（3）The processing of sea-buckthorn：Hippophate flavone is extracted, 95% edible alcohol is then dissolved in, it is standby to obtain Hippophate flavone solution
With；
（4）Wine brewing：By grape extraction juice, cold fermentation, grape wine is made in constant temperature ageing；
（5）Rectification：By step（1）、（2）With（3）Astragaloside IV solution, ganoderma active solution, the Hippophate flavone solution of gained add
Enter to step（4）In obtained grape wine, hybrid modulation produces.
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| CN201710682433.3A CN107384669A (en) | 2017-08-10 | 2017-08-10 | Grape wine with nourishing function and preparation method thereof |
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| CN201710682433.3A CN107384669A (en) | 2017-08-10 | 2017-08-10 | Grape wine with nourishing function and preparation method thereof |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530436A (en) * | 2009-04-20 | 2009-09-16 | 浙江省林业科学研究院 | Method of effectively extracting ganoderma triterpenoids and ganoderan from mythic fungus germ entity |
| CN102321514A (en) * | 2011-10-11 | 2012-01-18 | 张大宇 | Health-care wine |
| CN103131570A (en) * | 2011-11-25 | 2013-06-05 | 葛双铭 | Nourishing wine |
| CN104083389A (en) * | 2014-06-16 | 2014-10-08 | 湖南中医药大学 | Ischemic cerebrovascular disease treatment composition, medicament, preparation method and application |
| CN104388228A (en) * | 2014-12-02 | 2015-03-04 | 中法合营王朝葡萄酿酒有限公司 | Grape wine and making method thereof |
| CN105902586A (en) * | 2016-06-14 | 2016-08-31 | 南京华宽信息咨询中心 | Seabuckthorn flavone extraction method and seabuckthorn flavone extract |
| CN106581640A (en) * | 2016-12-20 | 2017-04-26 | 广州聚澜健康产业研究院有限公司 | Beautifying female health care wine for removing acnes |
-
2017
- 2017-08-10 CN CN201710682433.3A patent/CN107384669A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530436A (en) * | 2009-04-20 | 2009-09-16 | 浙江省林业科学研究院 | Method of effectively extracting ganoderma triterpenoids and ganoderan from mythic fungus germ entity |
| CN102321514A (en) * | 2011-10-11 | 2012-01-18 | 张大宇 | Health-care wine |
| CN103131570A (en) * | 2011-11-25 | 2013-06-05 | 葛双铭 | Nourishing wine |
| CN104083389A (en) * | 2014-06-16 | 2014-10-08 | 湖南中医药大学 | Ischemic cerebrovascular disease treatment composition, medicament, preparation method and application |
| CN104388228A (en) * | 2014-12-02 | 2015-03-04 | 中法合营王朝葡萄酿酒有限公司 | Grape wine and making method thereof |
| CN105902586A (en) * | 2016-06-14 | 2016-08-31 | 南京华宽信息咨询中心 | Seabuckthorn flavone extraction method and seabuckthorn flavone extract |
| CN106581640A (en) * | 2016-12-20 | 2017-04-26 | 广州聚澜健康产业研究院有限公司 | Beautifying female health care wine for removing acnes |
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