CN107384643A - A kind of antipruritic perfumed soap and preparation method thereof - Google Patents

A kind of antipruritic perfumed soap and preparation method thereof Download PDF

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Publication number
CN107384643A
CN107384643A CN201710776029.2A CN201710776029A CN107384643A CN 107384643 A CN107384643 A CN 107384643A CN 201710776029 A CN201710776029 A CN 201710776029A CN 107384643 A CN107384643 A CN 107384643A
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CN
China
Prior art keywords
parts
perfumed soap
antipruritic
preparation
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201710776029.2A
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Chinese (zh)
Inventor
戴文健
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NANJING JINGYUN CHEMICAL Co Ltd
Original Assignee
NANJING JINGYUN CHEMICAL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by NANJING JINGYUN CHEMICAL Co Ltd filed Critical NANJING JINGYUN CHEMICAL Co Ltd
Priority to CN201710776029.2A priority Critical patent/CN107384643A/en
Publication of CN107384643A publication Critical patent/CN107384643A/en
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00Compositions of detergents based essentially on soap
    • C11D9/04Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
    • C11D9/22Organic compounds, e.g. vitamins
    • C11D9/38Products in which the composition is not well defined
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

The invention provides a kind of antipruritic perfumed soap, it is made from the following raw materials in parts by weight:20 40 parts of sophora flower, 15 25 parts of balloonflower root, 10 20 parts of nutmeg, 15 25 parts of coix seed, 18 22 parts of citron, can play itching-relieving action, and the feature of environmental protection is good, and using effect is good and conveniently.

Description

A kind of antipruritic perfumed soap and preparation method thereof
Technical field
The present invention relates to a kind of antipruritic perfumed soap and preparation method thereof, belong to chemical technology field.
Background technology
As the improvement of people's living standards, for the demand also more and more higher of perfumed soap, sell extensively in the market Perfumed soap, it is largely allergic using made of chemicals, easily causing, also has some other side effects, Er Qie In price costly, be not suitable for a large amount of uses, there is the less of protective effect, or even the fat that can secrete skin to skin Fat protective ingredient washes, so that skin is dried very much, serious meeting injury skin.Many perfumed soap skin comfort degree, it is antipruritic Aspect effect is bad.
The content of the invention
Goal of the invention:It is an object of the invention to provide a kind of antipruritic perfumed soap and preparation method thereof.
Technical scheme:The purpose of the present invention is realized by following scheme:
A kind of antipruritic perfumed soap, is made from the following raw materials in parts by weight:Sophora flower 20-40 parts, balloonflower root 15-25 parts, nutmeg 10- 20 parts, coix seed 15-25 parts, citron 18-22 parts.
The antipruritic perfumed soap, is made from the following raw materials in parts by weight:30 parts of sophora flower, 20 parts of balloonflower root, 15 parts of nutmeg, Job's tears 20 parts of benevolence, 20 parts of citron.
The antipruritic perfumed soap, preparation method comprise the following steps:Material of getting it filled adds water to cook twice, collecting decoction, and decompression is dense Relative density is 1.15-1.20 medicinal extract when being reduced to 65 DEG C, adds ethanol the percent by volume of alcohol content is reached 75-85%, is stirred, Stand, filtering, relative density is 1.25-1.30 when filtrate decompression is concentrated into 65 DEG C, and reclaims ethanol, obtains concentrate, routinely Method is prepared into perfumed soap.
The antipruritic perfumed soap, in preparation method step, decocting condition is:Add 8-12 times that water is medicinal material weight for the first time Amount, decocts 1-2h, adds 6-10 times that water is medicinal material weight to measure for the second time, decocts 1-2h.
Application of the antipruritic perfumed soap in antipruritic perfumed soap is prepared.
Beneficial effect:Sophora flower of the present invention, balloonflower root, nutmeg, coix seed, citron are clearing heat and detoxicating, dispelling wind and eliminating dampness, the feature of environmental protection Good, antipruritic effect is good and conveniently.
Embodiment
Form by the following examples, the above of the present invention is described in further detail again, but should not be by this The scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following example, and all technologies for being realized based on the above of the present invention are equal Belong to the scope of the present invention.
Embodiment 1:20 parts of sophora flower, 25 parts of balloonflower root, 10 parts of nutmeg, 25 parts of coix seed, 18 parts of citron are taken, adds water to cook two Secondary, collecting decoction, relative density is 1.15 medicinal extract when being concentrated under reduced pressure into 65 DEG C, adds ethanol to reach the percent by volume of alcohol content 85%, stir, stand, filtering, relative density is 1.30 when filtrate decompression is concentrated into 65 DEG C, and reclaims ethanol, obtains concentrate, presses Conventional method is prepared into perfumed soap.
Embodiment 2:40 parts of sophora flower, 15 parts of balloonflower root, 20 parts of nutmeg, 15 parts of coix seed, 22 parts of citron are taken, adds water to cook two Secondary, collecting decoction, relative density is 1.20 medicinal extract when being concentrated under reduced pressure into 65 DEG C, adds ethanol to reach the percent by volume of alcohol content 75%, stir, stand, filtering, relative density is 1.25 when filtrate decompression is concentrated into 65 DEG C, and reclaims ethanol, obtains concentrate, presses Conventional method is prepared into perfumed soap.
Embodiment 3:30 parts of sophora flower, 20 parts of balloonflower root, 15 parts of nutmeg, 20 parts of coix seed, 20 parts of citron are taken, adds water to cook two Secondary, collecting decoction, relative density is 1.17 medicinal extract when being concentrated under reduced pressure into 65 DEG C, adds ethanol to reach the percent by volume of alcohol content 80%, stir, stand, filtering, relative density is 1.27 when filtrate decompression is concentrated into 65 DEG C, and reclaims ethanol, obtains concentrate, presses Conventional method is prepared into perfumed soap.
Embodiment 4:The present invention is to antipruritic influence result of the test.
Test material:Reagent:Antipruritic perfumed soap is prepared by embodiment 1-3 methods are prepared.
Experimental method:Take ICR mouse 40, male and female half and half, in advance 1d slough skin after mouse incidence ear hair it is standby, Lose hair or feathers position dextran 0.2mL/ times after each experimental group successive administration 3d, last medication 1h, produces mouse itch model.Will Itch model mice is randomly divided into model group, positive drug Compound Salicylic Acid Spirit group (1g/kg), external preparation high and low dose group in the present invention, Every group 10, corresponding dosage test medicine is uniformly applied to depilation position by each group respectively, and model group smears physiological saline, continuously Medication 3d.Being scratched one's head using mouse fore paw, portion, rear solid end scratch trunk, mouth stings each position of whole body as itch indication, after record tickles for the 1st time Mouse itch number in 15min.
The present invention is to itch model mice effect
Group Itch number/time/15min
Compound Salicylic Acid Spirit 5.34±1.45
Embodiment 1 4.13±1.76
Embodiment 2 4.89±1.37
Embodiment 3 5.12±1.98
Perfumed soap of the present invention has certain itching-relieving action to itch model mice.

Claims (5)

1. a kind of antipruritic perfumed soap, it is characterised in that be made from the following raw materials in parts by weight:Sophora flower 20-40 parts, balloonflower root 15-25 parts, Nutmeg 10-20 parts, coix seed 15-25 parts, citron 18-22 parts.
2. antipruritic perfumed soap as claimed in claim 1, it is characterised in that be made from the following raw materials in parts by weight:30 parts of sophora flower, balloonflower root 20 parts, 15 parts of nutmeg, 20 parts of coix seed, 20 parts of citron.
3. antipruritic perfumed soap as claimed in claim 1, it is characterised in that preparation method comprises the following steps:Material of getting it filled adds water to cook Twice, collecting decoction, relative density is 1.15-1.20 medicinal extract when being concentrated under reduced pressure into 65 DEG C, adds ethanol to make the volume of alcohol content Percentage reaches 75-85%, stirs, and stands, and filtering, relative density is 1.25-1.30 when filtrate decompression is concentrated into 65 DEG C, and is reclaimed Ethanol, concentrate is obtained, is prepared into perfumed soap according to a conventional method.
4. antipruritic perfumed soap as claimed in claim 3, it is characterised in that in preparation method step, decocting condition is:Add water for the first time 8-12 times for medicinal material weight is measured, and decocts 1-2h, is added 6-10 times that water is medicinal material weight to measure for the second time, is decocted 1-2h.
5. application of the antipruritic perfumed soap in antipruritic cosmetics as claimed in claim 1.
CN201710776029.2A 2017-09-01 2017-09-01 A kind of antipruritic perfumed soap and preparation method thereof Withdrawn CN107384643A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710776029.2A CN107384643A (en) 2017-09-01 2017-09-01 A kind of antipruritic perfumed soap and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710776029.2A CN107384643A (en) 2017-09-01 2017-09-01 A kind of antipruritic perfumed soap and preparation method thereof

Publications (1)

Publication Number Publication Date
CN107384643A true CN107384643A (en) 2017-11-24

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1840168A (en) * 2006-01-10 2006-10-04 孙小五 Medicinal soap for treating pruritus and preparation method thereof
CN102935133A (en) * 2012-12-08 2013-02-20 南京正宽医药科技有限公司 Traditional Chinese medicine composition for treating rheumatic arthritis as well as preparation method and application thereof
CN102940718A (en) * 2012-12-08 2013-02-27 南京正宽医药科技有限公司 Traditional Chinese medicine composition for treating constipation, preparation method and application
CN104762145A (en) * 2015-04-17 2015-07-08 谢松芬 Antipruritic toilet soap containing shrubby sophora extract

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1840168A (en) * 2006-01-10 2006-10-04 孙小五 Medicinal soap for treating pruritus and preparation method thereof
CN102935133A (en) * 2012-12-08 2013-02-20 南京正宽医药科技有限公司 Traditional Chinese medicine composition for treating rheumatic arthritis as well as preparation method and application thereof
CN102940718A (en) * 2012-12-08 2013-02-27 南京正宽医药科技有限公司 Traditional Chinese medicine composition for treating constipation, preparation method and application
CN104762145A (en) * 2015-04-17 2015-07-08 谢松芬 Antipruritic toilet soap containing shrubby sophora extract

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Application publication date: 20171124