CN107375612A - A kind of medicinal liquor for treating albiduria disease and preparation method thereof - Google Patents

A kind of medicinal liquor for treating albiduria disease and preparation method thereof Download PDF

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Publication number
CN107375612A
CN107375612A CN201710762478.1A CN201710762478A CN107375612A CN 107375612 A CN107375612 A CN 107375612A CN 201710762478 A CN201710762478 A CN 201710762478A CN 107375612 A CN107375612 A CN 107375612A
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CN
China
Prior art keywords
medicinal liquor
albiduria
disease
cordate houttuynia
treatment
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Pending
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CN201710762478.1A
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Chinese (zh)
Inventor
尹选平
唐锋
黄译锋
黄雄
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Nanning University
Nanning Institute
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Nanning Institute
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Publication of CN107375612A publication Critical patent/CN107375612A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention provides a kind of medicinal liquor for treating albiduria disease and preparation method thereof, the medicinal liquor is made up of hypoglaucous collett yam rhizome, white cordate houttuynia, corn wine, and the medicinal liquor prescription is simple, notable for treating the white disease of urine, especially purulence urine, chyluria effect highly significant.

Description

A kind of medicinal liquor for treating albiduria disease and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of medicinal liquor for treating albiduria disease and preparation method thereof.
Background technology
Normal urine is colourless or pale yellow transparent.It is white if there is urine --- rice washing water sample, lime water sample or The urine of milk sample white casse, clinically common urine have following three kinds of situations in vain:Crystalluria, purulence urine, chyluria.
Purulence urine is that urine is creamy white as caused by serious the urinary tract suppurative infection.Purulence urine be common in pyelonephritis, Cystitis, nephrapostasis, urethritis, or serious nephrophthisis.Chyluria is one of cardinal symptom of filariasis, urine color Bai Runiu Milk.Due to the chyle liquid (liquid after saponification of fats) of intestinal absorption, it is impossible to drained into from normal lymphatic vessel in blood circulation, Can only adverse current into the lymphatic vessel of urinary system, cause lymphatic vessel internal pressure in urinary system to increase, varicose and rupturing makes chyle liquid Overflow into urine, and chyluria occur.Chyluria is usually paroxysmal.When having red blood cell in chyluria, it is called hemotochyluria. In the blood and urine for suffering from hemotochyluria patient, it is young (i.e. young filaria) that microfilament can be found sometimes.Salt urine mostly occurs sub- children's winter Common, urine is in thin rice gruel sample, is mostly easily to precipitate after placement containing substantial amounts of phosphate or urine hydrochloric acid in original, such as urine is placed on It can become clear at once after being heated in bottle.Salt urine category normal physiological phenomena.Can not medication and be cured, it is important to drink plain boiled water more.This The purpose of invention is to provide a kind of medicinal liquor, and it can effectively treat the white disease of the urine such as purulence urine, chyluria, and the work(with kidney tonifying Yiyang Effect.
The content of the invention:
Specifically, the invention provides a kind of medicinal liquor and preparation method thereof for treating albiduria disease, the medicinal liquor is by hypoglaucous collett yam rhizome, white Cordate houttuynia, corn wine are made.The medicinal liquor prescription is simple, and preparation technology is simple, notable for treating the white disease of urine, especially purulence Property urine, chyluria effect highly significant.
Specifically, the invention provides a kind of medicinal liquor for treating albiduria disease, by hypoglaucous collett yam rhizome 10-20g, white cordate houttuynia 10- 20g, corn wine 2000ml are made.
Preferably, a kind of medicinal liquor for treating albiduria disease, by hypoglaucous collett yam rhizome 13-17g, cordate houttuynia 13-17g, corn wine 2000ml It is made.
It is highly preferred that it is made up of hypoglaucous collett yam rhizome 15g, cordate houttuynia 15g, corn wine 2000ml.
Present invention also offers a kind of preparation method for the medicinal liquor for treating albiduria disease, comprise the following steps:
(1) hypoglaucous collett yam rhizome of formula ratio is cleaned, is cut into 1mm thickness, with vapor boiling 3-7min, is put into jobstears wine and soaks Bubble.
(2) take the cordate houttuynia of formula ratio to clean, remove blade, cordate houttuynia is added in the corn wine in step (1), it is close Envelope, soak 10-15 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.
Corn wine alcoholic strength described above is preferably 30-50%VOL, more preferably 42%VOL.
Above-mentioned steps (1) are to clean the hypoglaucous collett yam rhizome of formula ratio, are cut into 1mm thickness, with vapor boiling 5min, are put into medicine jade Soaked in rice wine.
Above-mentioned steps (2) are that the cordate houttuynia for taking formula ratio is cleaned, and remove blade, the jade that cordate houttuynia is added in step (1) In rice wine, sealing, soak 10-15 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.
Beneficial effects of the present invention are:
The present invention shows that the medicinal liquor is made up of hypoglaucous collett yam rhizome, white cordate houttuynia, corn wine by clinical practice application.It is used for The white disease for the treatment of urine is notable, especially purulence urine, chyluria effect highly significant, and the medicinal liquor prescription is simple, and preparation technology is simple, controls It is low to treat cost.
In order that those of ordinary skill in the art are better understood from the present invention, the applicant has carried out a series of experiments and ground Study carefully, to prove the effect of the present invention:
1st, acute toxicity test:Healthy mice is taken separately to take 40 small white mouses to carry out formal test, experiment after carrying out trial test It is preceding that not water restriction, it was 20ml/kg that medicinal liquor dosage of the present invention, which is administered, is observed 7 days, normal diet by animal fasting 16 hours, Drinking-water, observation index is animal dead number.As a result, the concentration single administration (mouse) is observed 7 days, none dead mouse.
3.2 successive administration toxicity tests:Healthy mice 80 is taken, is randomly divided into 4 groups, investigational agent small dose group daily administration 1 time;Middle dose group is administered three times a day;Heavy dose of (100 times of adult human dose) are organized daily administration 6 times;Blank control group is to equivalent N.S;Tested according to acute oral toxicity, investigational agent is small, in, heavy dose of group dosage be 10ml/kg, successive administration 14 My god, normal diet is drunk water, Continuous Observation, and control group is same.Observation index is the weight of animals growth pattern, active situation, diet feelings Condition, excrement situation and death condition.As a result, for each group mouse without intoxication conditions, activity, diet drinking-water, excrement situation are normal, None is dead, and body weights carry out statistical procedures with blank control group, and p value is all higher than 0.05, and there was no significant difference.Experiment knot Fruit is shown in Table 3.
The successive administration toxicity test result of table 3
Test Summary:Experiment shows that preparation of the present invention is nontoxic, and security is good.
2nd, the clinical test of medicinal liquor of the present invention:
The present invention in Nanning City's outpatient service in 2016, with screening 10 be diagnosed as urine caused by purulence urine it is white, 10 make a definite diagnosis It is white to be urinated caused by chyluria, medicinal liquor treatment produced by the present invention is taken, daily in the morning, afternoon and evening three times, drinks 10-20ml every time, even It is continuous to take 7 days.As a result:Cure rate 50%, obvious effective rate 70%.And it is significantly better than and only steeps in wine that medicinal liquor is made is (effective with hypoglaucous collett yam rhizome Rate 30%), only cordate houttuynia is steep in wine (obvious effective rate 20%), is illustrated medicinal liquor reasonable recipe of the present invention, Synergistic, is played drug effect altogether.
Embodiment:
Embodiment 1:The preparation of the white sick medicinal liquor for the treatment of urine:
(1) 10g hypoglaucous collett yam rhizomes are cleaned, is cut into 1mm thickness, with vapor boiling 3min, is put into jobstears wine and soaks.
(2) take the cordate houttuynia of formula ratio to clean, remove blade, cordate houttuynia is added in the corn wine in step (1), it is close Envelope, soak 10 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.
Embodiment 2:The preparation of the white sick medicinal liquor for the treatment of urine:
(1) 13g hypoglaucous collett yam rhizomes are cleaned, is cut into 1mm thickness, with vapor boiling 5min, is put into jobstears wine and soaks.
(2) take 13g cordate houttuynia to clean, remove blade, cordate houttuynia is added in the corn wine in step (1), sealed, leaching Bubble 10 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.
Embodiment 3:The preparation of the white sick medicinal liquor for the treatment of urine:
(1) 15g hypoglaucous collett yam rhizomes are cleaned, is cut into 1mm thickness, with vapor boiling 5min, is put into jobstears wine and soaks.
(2) take 15g cordate houttuynia to clean, remove blade, cordate houttuynia is added in the corn wine in step (1), sealed, leaching Bubble 12 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.
Embodiment 4:The preparation of the white sick medicinal liquor for the treatment of urine:
(1) 17g hypoglaucous collett yam rhizomes are cleaned, is cut into 1mm thickness, with vapor boiling 5min, is put into jobstears wine and soaks.
(2) take 17g cordate houttuynia to clean, remove blade, cordate houttuynia is added in the corn wine in step (1), sealed, leaching Bubble 12 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.
Embodiment 5:The preparation of the white sick medicinal liquor for the treatment of urine:
(1) 10g hypoglaucous collett yam rhizomes are cleaned, is cut into 1mm thickness, with vapor boiling 7min, is put into jobstears wine and soaks.
(2) take 10g cordate houttuynia to clean, remove blade, cordate houttuynia is added in the corn wine in step (1), sealed, leaching Bubble 15 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.

Claims (8)

  1. A kind of 1. medicinal liquor for treating albiduria disease, it is characterised in that:By hypoglaucous collett yam rhizome 10-20g, white cordate houttuynia 10-20g, corn wine 2000ml is made.
  2. 2. the medicinal liquor for the treatment of albiduria disease according to claim 1, it is characterised in that:By hypoglaucous collett yam rhizome 13-17g, cordate houttuynia 13- 17g, corn wine 2000ml are made.
  3. 3. the medicinal liquor for the treatment of albiduria disease according to claim 1 or 2, it is characterised in that:By hypoglaucous collett yam rhizome 15g, cordate houttuynia 15g, corn wine 2000ml are made.
  4. A kind of 4. preparation method for the medicinal liquor for treating albiduria disease, it is characterised in that:Comprise the following steps:
    (1) hypoglaucous collett yam rhizome of formula ratio is cleaned, is cut into 1mm thickness, with vapor boiling 3-7min, is put into jobstears wine and soaks;
    (2) take the cordate houttuynia of formula ratio to clean, remove blade, cordate houttuynia is added in the corn wine in step (1), sealed, leaching Bubble 10-15 days, that is, obtain medical treatment and urinate the medicinal liquor of white disease.
  5. 5. according to the medicinal liquor of any described treatment albiduria diseases of claim 1-3, it is characterised in that:Described corn wine alcoholic strength Preferably 30-50%VOL.
  6. 6. according to the medicinal liquor of any described treatment albiduria diseases of claim 1-3, it is characterised in that:Described corn wine alcoholic strength Preferably 42%VOL.
  7. 7. the preparation method of the medicinal liquor for the treatment of albiduria disease according to claim 4, it is characterised in that:Step (1) be by with The hypoglaucous collett yam rhizome just measured is cleaned, and is cut into 1mm thickness, with vapor boiling 5min, is put into jobstears wine and soaks.
  8. 8. the preparation method of the medicinal liquor for the treatment of albiduria disease according to claim 4, it is characterised in that:Step (2) is to take to match somebody with somebody The cordate houttuynia just measured is cleaned, and removes blade, cordate houttuynia is added in the corn wine in step (1), sealing, immersion 10-15 days, i.e., Obtain medical treatment and urinate the medicinal liquor of white disease.
CN201710762478.1A 2017-08-30 2017-08-30 A kind of medicinal liquor for treating albiduria disease and preparation method thereof Pending CN107375612A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1005336A1 (en) * 1997-07-09 2000-06-07 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
WO2001068085A1 (en) * 2000-03-15 2001-09-20 Genaera Corporation A method for stimulation of defensin production
CN106924581A (en) * 2017-03-30 2017-07-07 南宁学院 It is a kind of to treat medicinal liquor of stomachache and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1005336A1 (en) * 1997-07-09 2000-06-07 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
WO2001068085A1 (en) * 2000-03-15 2001-09-20 Genaera Corporation A method for stimulation of defensin production
CN106924581A (en) * 2017-03-30 2017-07-07 南宁学院 It is a kind of to treat medicinal liquor of stomachache and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
中华人民共和国卫生部药典委员会: "《中华人民共和国药典一九七七年版一部》", 31 December 1978, 人民卫生出版社 *
彭芳胜等: "《土家医治毒药物集》", 31 January 2014, 中医古籍出版社 *

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Application publication date: 20171124