CN107375571A

CN107375571A - Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch and preparation method thereof

Info

Publication number: CN107375571A
Application number: CN201710801728.8A
Authority: CN
Inventors: 唐斌斌; 杜书君
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-09-07
Filing date: 2017-09-07
Publication date: 2017-11-24

Abstract

The invention belongs to medicine new external preparation field, more particularly to a kind of prescriptions of traditional Chinese medicine for treating hypertension is combined with traditional Chinese medical science magnetic therapy, and the preparation pasted by point medicine bar cloth.Including Chinese medicinal component, high-performance nano NdFeB magnetic powder and suitable water-soluble material, the Chinese medicinal component includes following effective Chinese herbal medicine according to parts by weight：Ginkgo leaf, the red sage root, safflower, plantain seed, rhizoma alismatis, the root of bidentate achyranthes, cassia seed, Poria cocos, polygala, stir-baked SEMEN ZIZIPHI SPINOSAE, radix scutellariae, Ligusticum wallichii, the bark of eucommia, the dried rhizome of rehmannia, the root of herbaceous peony, borneol, camphor, the present invention makes full use of Traditional Chinese Medicine advantage, prescription after dialectical treatmert, combined magnetic field therapy, successfully develop the Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch that hypertension is treated by point medicine, it acts on safety, it is curative for effect, it is single to solve current medicine effect, duration of efficacy is short, the drawbacks such as patient needs to take medicine repeatedly and long-term prescription occurs lesions of liver and kidney and gastrointestinal side effect, with boundless market promotion prospect.

Description

Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch and preparation method thereof

Technical field

The invention belongs to medicine new external preparation field, more particularly to a kind of prescriptions of traditional Chinese medicine and the traditional Chinese medical science for treating hypertension Magnetic therapy is combined, and the preparation pasted by point medicine bar cloth.

Background technology

Hypertension is common clinical, frequently-occurring disease, and the existing hyperpietic in China is more than 200,000,000 people according to statistics, and ill The trend that rate also rises year by year.Hypertension is most common cardiovascular disease, is the great public health problem in global range. Predicted according to the World Health Organization, to the year two thousand twenty, angiocardiopathy endangers the number one killer of human health by substituting infectious disease to turn into, And hypertension is the arch-criminal of angiocardiopathy, there is the characteristics of high incidence, low control rate.Therefore Efforts To Develop hypertension The preventing and treating of disease, active treatment patients with hypertension are very urgent.

For motherland's medical science without hypertension name of disease, it belongs to the categories such as " headache ", " dizziness ", " apoplexy ".《Interior warp》Record： " all wind trembling and dizziness, come under liver ", " then nose heave height shakes kidney deficiency, marrow sea deficiency, then vertigo and tinnitus ".Think this sick dizziness and liver kidney It is relevant.《Prescriptions worth thousand gold》Point out：" headache due to upward adverse flow of liver-QI, irascibility are fainted inverse, rising brains." " its pain must push up to mountain peak, with the arteries and veins and governor vessel of liver Can in mountain peak therefore ... headache due to upward adverse flow of liver-QI must more dizziness ".It is that irascibility is fainted against caused to think headache, dizziness.《Danxi's experiential therapy》Say：" nothing Phlegm is not dizzy, and no fire is not dizzy." think that phlegm and fire are another reasons for causing this disease.Traditional Chinese medicine thinks that this disease is mainly lost by feelings will Tune, eating and drinking without temperance, work and rest excessively, insufficiency of natural endowment and constitution contain the factor such as decline partially partially and trigger, cause viscera equilibrium between yin and yang to lose Adjust, qi depression to blood stasis, disturbance in ascending and descending, it is raw in wind fire, phlegm-blood stasis and hand over resistance and fall ill.Liver kidney imbalance of yin and yang be morbidity emphasis, its interpretation of the cause, onset and process of an illness Main points can be summarized as empty (deficiency of liver-yin and kidney-yin), fiery (irascibility, liver-yang), wind (liver wind), phlegm (phlegm wet), gas (circulation of vital energy in the wrong direction, the stagnation of the circulation of vital energy), blood (blood The stasis of blood) etc. six aspect.Feature is simulataneous insufficiency and excessive, empty in caused by liver and kidney deficiency, asthenia of essence and blood, really in liver-yang hyperactivity, qi depression to blood stasis, phlegm Essential resistance of turbid.The present invention passes through diagnosis and treatment according to above-mentioned theory of traditional Chinese medical science, it is proposed that the prescription of the invention, has calming the liver, change Phlegm relieves dizziness, high fever, infantile convulsions, epilepsy, etc., tonify the liver and kidney effect, and for treating hypertension, effect safety is curative for effect.

Transdermal therapeutic system (TTS) is an emerging field of pharmacy, and compared with traditional administering mode, having to produce Raw lasting, constant and controllable blood concentration, reduces administration number of times and dosage, avoids the first pass effect of liver, mitigates bad anti- Should；Improve the bioavilability of medicine；The advantages that easy to use.Therefore, transdermal therapeutic system has a good application prospect, and draws People are played more and more to pay close attention to.Wherein cataplasm has the characteristics of compatibility to skin is good, and drugloading rate is big, it has also become Chinese medicine " new lover " of preparation developer.

Magnetic field therapy, also known as " magnetotherapy ", " acipoint magnetotheraphy ", are to allow magnetic fields to make in the certain position of human body or acupuncture point The magnetic line of force penetrates tissue depths, to treat a kind of method of disease.China is to be cured the disease earliest state using magnetic therapy in the world Family.B.C. 180 years, Han dynasty historian's Ssu-ma Chien existed《Records of the Historian Bian Que storehouse public affairs biographies》Described in：" neat king waits upon doctor and satisfies disease, from Refine five stones (magnetite, realgar, Zeng Qing, cinnabar, Bai Ji) and take it, the hot person that do not urinate, can not take five stones in mouth." Eastern Han Dynasty《Legendary god of farming's book on Chinese herbal medicine Through》One book is also loaded with " magnetite acrid flavour is cold in nature, main general arthralgia, rheumatism, oncotic arthralgia of limbs, can not hold thing ".Northern and Southern Dynasties' Tao Hong scapes think magnetic Stone has therapeutic actions such as " support kidney, strong moral integrity, kidney-nourishing relieving restlessness, get round by bribery, the pain that disappears is swollen ".The Tang Dynasty doctor's SUN Si miao exists《Preemergency thousand Jin Yaofang》It is loaded with and controls metal-inflicted wound with " magnetite smashes end and applies it, relieves pain disconnected blood ".Ming Dynasty Li Shizhen (1518-1593 A.D.)《Compendium of Materia Medica》In to magnetite Cure the disease comprehensive and detailed record of also contrasting.Foreign country is also relatively early using magnetic therapy, and 200 years Christian eras Zeng Youyong magnetites make cathartic Record.450 years Christian eras, once there was the report for holding magnetite treatment gout in Greece.1000 Christian eras Arabic treats liver with magnetite Disease.16th century, Swiss with magnetite treated prolapse of the anus, the disease such as edema.Occur the magnetotherapy appliances such as tape in succession later.20th century 50 The age Zeng Youyong magnetic Blood pressure decresing belt treatment report such as hypertension and neurasthenia.The international bio magnetics meeting of first time in 1961 Afterwards, this frontier science of generation biomagnetism.Magnetic field can be used for treating a variety of diseases, such as hypertension, high fat of blood, nerve head Bitterly, neurasthenia, facial spasm, bronchitis, enteritis, canker, cervical spondylopathy, pain in waist and lower extremities, acute lumbar muscle sprain, lumbar muscle strain, Cholecystalgia, Biliary Calculi, lithangiuria, rhinitis, dermatitis, phlebitis etc..

In terms of hypertension therapeutic, although chemical drugs effect is rapid, fluctuation of blood pressure is big in pressure reduction, and side effect is also big, The organs such as the coup injury heart, brain, kidney, while these medicines, to high fat of blood, high blood is viscous, the nothing such as vascular sclerosis, the damage of target organ Improvement result.Blood pressure drops after usually there is medication, has dropped and has risen, and again and again, forms vicious circle.

The content of the invention

It is of the invention to be directed to the problems of above-mentioned existing hypertension therapeutic medicine, propose that a kind of formula is reasonable, act on Safety, it is curative for effect, solve that the effect of current medicine is single, the short Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch of duration of efficacy and Its preparation method.

In order to achieve the above object, the technical solution adopted by the present invention is that the present invention provides a kind of Chinese medicine for lowering high blood pressure acupoint magnetic A bar cloth patch is treated, including Chinese medicinal component, high-performance nano NdFeB magnetic powder and suitable water-soluble material, the Chinese medicinal component are pressed Include following effective Chinese herbal medicine according to parts by weight：20 parts~50 parts of ginkgo leaf, 20 parts~40 parts of the red sage root, 20 parts~40 parts of safflower, 30 parts~50 parts of plantain seed, 20 parts~40 parts of rhizoma alismatis, 20 parts~40 parts of the root of bidentate achyranthes, 30 parts~50 parts of cassia seed, Poria cocos 30 parts~50 Part, 50 parts~70 parts of polygala, 20 parts~40 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 20 parts~40 parts of radix scutellariae, 20 parts~40 parts of Ligusticum wallichii, the bark of eucommia 20 parts~40 Part, 20 parts~40 parts of the dried rhizome of rehmannia, 20 parts~40 parts of the root of herbaceous peony, 1 part~5 parts of borneol, 1 part~5 parts of camphor, wherein, the Chinese medicinal component 90% be used to prepare Chinese medical concrete, 10% is used to prepare nano traditional Chinese medicine powder, the Chinese medicinal component, high-performance nano neodymium iron boron Mass ratio between magnetic and water-soluble material is 22~35:0.001~0.006:15~52.

Preferably, the Chinese medicinal component includes 40 parts of ginkgo leaf, 30 parts of the red sage root, 25 parts of safflower, 40 parts of plantain seed, rhizoma alismatis 30 parts, 30 parts of the root of bidentate achyranthes, 40 parts of cassia seed, 40 parts of Poria cocos, 60 parts of polygala, 30 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 30 parts of radix scutellariae, 30 parts of Ligusticum wallichii, the bark of eucommia 30 parts, 30 parts of the dried rhizome of rehmannia, 30 parts of the root of herbaceous peony, 3 parts of borneol, 3 parts of camphor.

Preferably, the suitable water-soluble material includes following active principle：The Sodium Polyacrylate NP- that part neutralizes 700th, Sodium Polyacrylate NP-800, sodium carboxymethylcellulose, glycerine, aluminum glycinate, citric acid, the ethylenediamine tetrem of part neutralization Acid disodium and ethylparaben.

Present invention also offers the method for preparing Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch, including following effective procedure：

A, weigh：The Chinese herbal medicine of the good corresponding parts by weight in addition to borneol and camphor is weighed first；

B, distribute：By the Chinese herbal medicine weighed according to weight than 9:1 ratio, it is distributed into two parts；

C, Chinese medical concrete is prepared：9~10 times of drinking water immersion 2h will be added after a Chinese herbal medicine coarse crushing of heavier-weight, decocted Boil 1 hour, filtering, collect extraction decoction；Second plus 7~8 times of amounts of drinking water, are warming up to boiling and decoct 30~40 minutes, mistake Filter, collect extraction decoction；Decoction is extracted in merging twice, filters again, collects filtered fluid, medicinal extract shape is then concentrated into, in obtaining Medicine medicinal extract, it is standby；

D, nano traditional Chinese medicine powder is prepared：Remaining a Chinese herbal medicine is put into nano-level grinder, is ground to nanometer Grain size, obtains nano traditional Chinese medicine powder, standby；

Stock：Taken according to respective quality percentage：Sodium Polyacrylate NP-7001%~3% that part neutralizes, part neutralize Sodium Polyacrylate NP-8001.5%~3%, sodium carboxymethylcellulose 1%~4%, glycerine 10%~30%, aluminum glycinate 0.2%~0.5%, citric acid 0.2%~0.5%, disodium ethylene diamine tetraacetate 0.02%~0.1%, Chinese medical concrete 20%~ 30%, nano traditional Chinese medicine powder 2%~5%, high-performance nano NdFeB magnetic powder 0.001%~0.006%, borneol 1%~5%, Camphor 1%~5%, ethylparaben 0.05%~0.15%, surplus are water；

Prepare bar cloth emplastrum body：Sodium Polyacrylate NP-700, Sodium Polyacrylate NP-800, aluminum glycinate, carboxymethyl is fine Tie up plain sodium, nano traditional Chinese medicine powder and high-performance nano NdFeB magnetic powder to be dispersed in glycerine, as A phases；Citric acid, second two Amine tetraacethyl disodium is soluble in water to be used as B phases；Borneol, camphor and ethylparaben, which are dissolved in ethanol in proper amount, is used as C phases；By B phases Add several times in A phases, after stirring, sequentially add Chinese medical concrete and C phases, stirring 20min obtains a bar cloth emplastrum body；

Finished product：An obtained bar cloth emplastrum body is coated, cut, that is, obtains Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch.

Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch provided by the present invention, it is used for hypertension therapeutic.

Compared with prior art, the advantages and positive effects of the present invention are,

1st, the present invention makes full use of Traditional Chinese Medicine advantage, prescription after dialectical treatmert, combined magnetic field therapy, successfully develops logical The Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch of point medicine treatment hypertension is crossed, it acts on safety, curative for effect, solves current medicine Thing effect is single, and duration of efficacy is short, the lesions of liver and kidney and intestines and stomach that patient needs to take medicine repeatedly and long-term prescription occurs The drawbacks such as adverse reaction, there is boundless market promotion prospect.

Embodiment

In order to be more clearly understood that the above objects, features and advantages of the present invention, with reference to embodiment to this hair It is bright to be described further.It should be noted that in the case where not conflicting, the feature in embodiments herein and embodiment can To be mutually combined.

Many details are elaborated in the following description to facilitate a thorough understanding of the present invention, still, the present invention may be used also To be implemented using other modes described here are different from, therefore, the present invention is not limited to the specific of specification described below The limitation of embodiment.

In Chinese herbal medicine used in the present invention, ginkgo leaf, the red sage root, safflower, the root of bidentate achyranthes, stir-baked SEMEN ZIZIPHI SPINOSAE, Ligusticum wallichii and the bark of eucommia play Promoting blood circulation, the effect of expansion blood vessel, and then the purpose being depressured, plantain seed, Poria cocos, rhizoma alismatis, radix scutellariae are by suppressing renal tubule pair The re-absorption of sodium and water, reach natriuretic diuretic effect, the discharge rate for making one internal sodium and water exceedes intake, makes blood volume and carefully Extracellular liquid measure is reduced, and cardiac output declines, and reaches antihypertensive effect；Cassia seed, polygala, the dried rhizome of rehmannia, the root of herbaceous peony, borneol, camphor play Calm the nerves, alleviate the effect that high pressure is had a headache, and high-performance nano NdFeB magnetic powder can be in human body surface physiology magnetic field, magnetic field energy The excitability of nerve endings is reduced by the change of field shape and gradient, blood vessel is expanded, stimulates circulation, risen in a certain degree To the effect for the treatment of hypertension, meanwhile, the expansion of blood vessel is also beneficial to the further absorption of medicine.The polyacrylic acid that part neutralizes The main purpose of sodium is thickening, stable and water conservation；Glycerine can constantly absorb moisture from air, and then promote in nanometer Medicinal powder end is lasting to play a role；The main purpose of sodium carboxymethylcellulose is thickening, stable and water conservation；Aluminum glycinate can Local perspiration is reduced, ensures Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch long-acting treatment；Citric acid can promote the metabolism of human body, And then the quick purpose for absorbing the property of medicine；Disodium ethylene diamine tetraacetate can prevent and treat calcium, magnesium, iron, manganese etc. as water treatment agent The harmful effect that metal ion is brought.

Embodiment 1, the present embodiment provide a kind of Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch

Ginkgo leaf 40g, red sage root 30g, safflower 25g, plantain seed 40g, rhizoma alismatis 30g, root of bidentate achyranthes 30g, cassia seed are weighed first 40g, Poria cocos 40g, polygala 60g, stir-baked SEMEN ZIZIPHI SPINOSAE 30g, radix scutellariae 30g, Ligusticum wallichii 30g, bark of eucommia 30g, dried rhizome of rehmannia 30g, root of herbaceous peony 30g.

Then by the Chinese herbal medicine weighed according to weight than 9:1 ratio, two parts are distributed into, i.e., ginkgo leaf is divided into 36g And 4g, the red sage root are divided into 27g and 3g, the rest may be inferred, and the Chinese herbal medicine weighed is divided into two parts.

Then 9~10 times of drinking water immersion 2h will be added after a Chinese herbal medicine coarse crushing of heavier-weight, decoct 1 hour, steam During boiling, volatile oil is collected, after the completion of decoction, filtering, collects extraction decoction；Then, then second of boiling is carried out, second Secondary plus 7~8 times of amounts of drinking water, are warming up to boiling and decoct 30~40 minutes, then filter, collect extraction decoction；Merging carries twice Taking liquid, filter again, collect filtered fluid, be then concentrated into medicinal extract shape, add the volatile oil of collection, that is, obtain Chinese medical concrete, It is standby；

Then, remaining a Chinese herbal medicine is put into nano-level grinder, is ground to nano particle size, obtains nanometer Herb powder, it is standby；

Then, NP-7003g, NP-8002g, sodium carboxymethylcellulose 2g, aluminum glycinate 0.4g, nano traditional Chinese medicine powder are weighed After 5g and high-performance nano NdFeB magnetic powder 4.0mg is well mixed, it is scattered in 30g glycerine and obtains A phases.

Citric acid 0.4g is weighed, disodium ethylene diamine tetraacetate 0.05g, is dissolved in 31g water and obtains B phases.

Borneol 3g is weighed, camphor 3g, ethylparaben 0.15g, is dissolved in a small amount of ethanol and obtains C phases.

B phases are added in A phases several times and stirred, obtain sticky lotion, then sequentially add Chinese medical concrete 30g and C Phase, stirring 20min obtain cataplasm lotion.

Lotion is coated on medical non-woven fabrics with 2mm thickness, after covering adherent layer, is placed in temperature as 37 DEG C, relatively Humidity is dried in the environment of being 50%, cuts into 8cm × 10cm specification, packs the Chinese medicine for lowering high blood pressure acupoint magnetotherapy for producing the present invention Ba Bu is pasted.

Effect experiment：

With spontaneous hypertensive rat (SHR) for animal pattern, the SHR48 of 11 week old male and female half and half is only randomly divided into 6 Group:Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch group (A groups)；Without prescription drug nanometer powder, the Chinese medicine that medicinal extract is made all is extracted into It is depressured acupoint magnetotherapy bar cloth patch (B groups)；The Chinese medicine for lowering high blood pressure acupuncture point bar cloth patch group (C groups) of nonmagnetic material；Only magnetisable material Ba Bu pastes (D groups)；Commercially available treatment hypertension drug group (E groups) and blank control group (F groups).To each group SHR blood pressure before experiment Handled using the t methods of inspection, as a result showing each group animal, there was no significant difference in terms of blood pressure (p ＞ 0.05).Every group of animal connects Continuous administration 4 weeks, A, B and C group use 48h per note, and D groups are used by ormal weight.Administration measures the blood pressure of each group rat after terminating, respectively Survey 3 times and average.After pharmaceutical intervention, A groups and B groups rat blood pressure reduce (P compared with F groups<0.01,P<0.01)；C group rat blood pressures (P is reduced compared with F groups<0.05)；D groups rat blood pressure reduces compared with F groups, but without significant；A groups rat blood pressure reduces (P compared with E groups< 0.05)；B, C and D groups rat blood pressure compared with E groups without significant.As a result show that though alone Chinese medicine or magnetisable material can drop Pressure, but DeGrain, synergy is produced after Papillary, antihypertensive effect is obvious.

After A groups and B component are not acted on into SHR rats, start to measure blood pressure every 1h after 2h measurement blood pressures, 24h, Each survey 3 times is averaged, and continuous measurement is until blood pressure is returned to untill raw water puts down or raised, the results showed that A group blood pressures are anti- 17 hours slower than B groups time of bullet, it can be seen that, the nano traditional Chinese medicine powder in A groups is considered as the second drug storage warehouse, delaying The rate of release of active ingredient, so as to extending the duration of decompression.

Embodiment 2, the present embodiment provide a kind of Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch

Ginkgo leaf 20g, red sage root 20g, safflower 20g, plantain seed 30g, rhizoma alismatis 20g, root of bidentate achyranthes 20g, cassia seed are weighed first 30g, Poria cocos 30g, polygala 50g, stir-baked SEMEN ZIZIPHI SPINOSAE 20g, radix scutellariae 20g, Ligusticum wallichii 20g, bark of eucommia 20g, dried rhizome of rehmannia 20g, root of herbaceous peony 20g.

Then by the Chinese herbal medicine weighed according to weight than 9:1 ratio, two parts are distributed into, i.e., ginkgo leaf is divided into 18g And 2g, the red sage root are divided into 18g and 2g, the rest may be inferred, and the Chinese herbal medicine weighed is divided into two parts.

Then, NP-7001g, NP-8001.5g, sodium carboxymethylcellulose 1g, aluminum glycinate 0.2g, Nano Chinese medicine powder are weighed After last 1g and high-performance nano NdFeB magnetic powder 1.0mg is well mixed, it is scattered in 10g glycerine and obtains A phases.

Citric acid 0.2g is weighed, disodium ethylene diamine tetraacetate 0.02g, is dissolved in 22g water and obtains B phases.

Borneol 1g is weighed, camphor 1g, ethylparaben 0.01g, is dissolved in a small amount of ethanol and obtains C phases.

B phases are added in A phases several times and stirred, obtain sticky lotion, then sequentially add Chinese medical concrete 20g and C Phase, stirring 20min obtain cataplasm lotion.

After A groups and B component are not acted on into SHR rats, start to measure blood pressure every 1h after 2h measurement blood pressures, 24h, Each survey 3 times is averaged, and continuous measurement is until blood pressure is returned to untill raw water puts down or raised, the results showed that A group blood pressures are anti- 16 hours slower than B groups time of bullet, it can be seen that, the nano traditional Chinese medicine powder in A groups is considered as the second drug storage warehouse, delaying The rate of release of active ingredient, so as to extending the duration of decompression.

Embodiment 3, the present embodiment provide a kind of Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch

Ginkgo leaf 50g, red sage root 40g, safflower 40g, plantain seed 50g, rhizoma alismatis 40g, root of bidentate achyranthes 40g, cassia seed 50g, Poria cocos 50g, polygala 70g, stir-baked SEMEN ZIZIPHI SPINOSAE 40g, radix scutellariae 40g, Ligusticum wallichii 40g, bark of eucommia 40g, dried rhizome of rehmannia 40g, root of herbaceous peony 40g.

Then by the Chinese herbal medicine weighed according to weight than 9:1 ratio, two parts are distributed into, i.e., ginkgo leaf is divided into 45g And 5g, the red sage root are divided into 36g and 4g, the rest may be inferred, and the Chinese herbal medicine weighed is divided into two parts.

Then, NP-700 Sodium Polyacrylates 3g, NP-800 Sodium Polyacrylate 3g, sodium carboxymethylcellulose 4g, sweet ammonia are weighed After sour aluminium 0.5, nano traditional Chinese medicine powder 5g and high-performance nano NdFeB magnetic powder 6.0mg are well mixed, it is scattered in 10g glycerine and obtains To A phases.

Citric acid 0.5g is weighed, disodium ethylene diamine tetraacetate 0.1g, is dissolved in 45g water and obtains B phases.

Borneol 5g is weighed, camphor 5g, ethylparaben 0.15g, is dissolved in a small amount of ethanol and obtains C phases.

After A groups and B component are not acted on into SHR rats, start to measure blood pressure every 1h after 2h measurement blood pressures, 24h, Each survey 3 times is averaged, and continuous measurement is until blood pressure is returned to untill raw water puts down or raised, the results showed that A group blood pressures are anti- 16.5 hours slower than B groups time of bullet, it can be seen that, the nano traditional Chinese medicine powder in A groups is considered as the second drug storage warehouse, prolonging The rate of release of active ingredient is delayed, so as to extend the duration of decompression.

Comprehensive Correlation：The time that comparative example 1 rebounds with embodiment 2, the blood pressure of embodiment 3, it is found that embodiment 1 is provided Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch, it is provided by the present invention next to that embodiment 3, is finally embodiment 2, to sum up contrasts Optimum formula is embodiment 1.

The above described is only a preferred embodiment of the present invention, being not the limitation for making other forms to the present invention, appoint What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc. Effect embodiment is applied to other fields, but every without departing from technical solution of the present invention content, the technical spirit according to the present invention Any simple modification, equivalent variations and the remodeling made to above example, still fall within the protection domain of technical solution of the present invention.

Claims

1. a kind of Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch, it is characterised in that including Chinese medicinal component, high-performance nano NdFeB magnetic powder And suitable water-soluble material, the Chinese medicinal component include following effective Chinese herbal medicine according to parts by weight：20 parts of ginkgo leaf~ 50 parts, 20 parts~40 parts of the red sage root, 20 parts~40 parts of safflower, 30 parts~50 parts of plantain seed, 20 parts~40 parts of rhizoma alismatis, 20 parts of the root of bidentate achyranthes~ 40 parts, 30 parts~50 parts of cassia seed, 30 parts~50 parts of Poria cocos, 50 parts~70 parts of polygala, 20 parts~40 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 20 parts of radix scutellariae ~40 parts, 20 parts~40 parts of Ligusticum wallichii, 20 parts~40 parts of the bark of eucommia, 20 parts~40 parts of the dried rhizome of rehmannia, 20 parts~40 parts of the root of herbaceous peony, borneol 1 part~5 Part, 1 part~5 parts of camphor, wherein, the 90% of the Chinese medicinal component is used to prepare Chinese medical concrete, and 10% is used to prepare nano traditional Chinese medicine Powder, the mass ratio between the Chinese medicinal component, high-performance nano NdFeB magnetic powder and water-soluble material are 22~35: 0.001~0.006:15~52.

2. Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch according to claim 1, it is characterised in that the Chinese medicinal component includes silver 40 parts of apricot leaf, 30 parts of the red sage root, 25 parts of safflower, 40 parts of plantain seed, 30 parts of rhizoma alismatis, 30 parts of the root of bidentate achyranthes, 40 parts of cassia seed, 40 parts of Poria cocos, 60 parts of polygala, 30 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 30 parts of radix scutellariae, 30 parts of Ligusticum wallichii, 30 parts of the bark of eucommia, 30 parts of the dried rhizome of rehmannia, 30 parts of the root of herbaceous peony, 3 parts of borneol, camphor 3 parts.

3. Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch according to claim 2, it is characterised in that the suitable water-soluble material Material includes following active principle：The Sodium Polyacrylate NP-700 of part neutralization, the Sodium Polyacrylate NP-800 of part neutralization, carboxylic first Base sodium cellulosate, glycerine, aluminum glycinate, citric acid, disodium ethylene diamine tetraacetate and ethylparaben.

4. prepare described in above-mentioned 1~3 any one Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch method, it is characterised in that including with Lower effective procedure：

C, Chinese medical concrete is prepared：9~10 times of drinking water immersion 2h will be added after a Chinese herbal medicine coarse crushing of heavier-weight, decoct 1 Hour, filtering, collect extraction decoction；Second plus 7~8 times of amounts of drinking water, are warming up to boiling and decoct 30~40 minutes, filtering, Collect extraction decoction；Decoction is extracted in merging twice, filters again, collects filtered fluid, is then concentrated into medicinal extract shape, obtains Chinese medicine leaching Cream, it is standby；

D, nano traditional Chinese medicine powder is prepared：Remaining a Chinese herbal medicine is put into nano-level grinder, it is big to be ground to nano particle It is small, nano traditional Chinese medicine powder is obtained, it is standby；

E, stock up：Taken according to respective quality percentage：Sodium Polyacrylate NP-7001%~3% that part neutralizes, what part neutralized Sodium Polyacrylate NP-8001.5%~3%, sodium carboxymethylcellulose 1%~4%, glycerine 10%~30%, aluminum glycinate 0.2%~0.5%, citric acid 0.2%~0.5%, disodium ethylene diamine tetraacetate 0.02%~0.1%, Chinese medical concrete 20%~ 30%, nano traditional Chinese medicine powder 2%~5%, high-performance nano NdFeB magnetic powder 0.001%~0.006%, borneol 1%~5%, Camphor 1%~5%, ethylparaben 0.05%~0.15%, surplus are water；

F, bar cloth emplastrum body is prepared：By Sodium Polyacrylate NP-700, Sodium Polyacrylate NP-800, aluminum glycinate, carboxymethyl cellulose Plain sodium, nano traditional Chinese medicine powder and high-performance nano NdFeB magnetic powder are dispersed in glycerine, as A phases；Citric acid, ethylenediamine Tetraacethyl disodium is soluble in water to be used as B phases；Borneol, camphor and ethylparaben, which are dissolved in ethanol in proper amount, is used as C phases；By B phases point Repeatedly add in A phases, after stirring, sequentially add Chinese medical concrete and C phases, stirring 20min obtains a bar cloth emplastrum body；

G, finished product：An obtained bar cloth emplastrum body is coated, cut, that is, obtains Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch.

5. the Chinese medicine for lowering high blood pressure acupoint magnetotherapy bar cloth patch as described in any one of claims 1 to 3, it is used for hypertension therapeutic.