CN107375252B - Moxibustion patch and moxibustion patch combination - Google Patents

Moxibustion patch and moxibustion patch combination Download PDF

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CN107375252B
CN107375252B CN201710699838.8A CN201710699838A CN107375252B CN 107375252 B CN107375252 B CN 107375252B CN 201710699838 A CN201710699838 A CN 201710699838A CN 107375252 B CN107375252 B CN 107375252B
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chinese herbal
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CN107375252A (en
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吕鹏举
周学刚
郭爽
蔡明霏
陈宇格
严俊
高增林
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Harbin Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/235Foeniculum (fennel)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

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Abstract

The invention discloses a novel moxibustion patch which comprises a base layer, and a heat source layer, a Chinese herbal medicine essential oil layer, a Chinese herbal medicine powder layer, a moxa layer and an essential oil guide layer which are sequentially arranged on the base layer, wherein medicine powder in the Chinese herbal medicine powder layer and medicine essential oil in the Chinese herbal medicine essential oil layer are prepared by the following method of selecting a traditional Chinese medicine formula for symptomatic treatment, respectively taking each raw material according to the formula, classifying each raw material according to oil yielding properties, dividing each raw material into an oil-yielding Chinese herbal medicine and an oil-yielding Chinese herbal medicine, grinding the divided oil-yielding Chinese herbal medicine into powder to obtain medicine powder, extracting medicinal component essential oil from the divided oil-yielding Chinese herbal medicine by adopting a microwave extraction technology, and wrapping the medicine essential oil by adopting β -cyclodextrin.

Description

Moxibustion patch and moxibustion patch combination
Technical Field
The invention belongs to the technical field of traditional Chinese medicine moxibustion, and particularly relates to a novel moxibustion patch and a moxibustion patch combination.
Background
Folium Artemisiae Argyi is warm in nature, reaching the muscle layer with heat, warming qi and promoting blood circulation. The moxibustion has the effects of warming and dredging channels and collaterals, dispelling cold and removing dampness, regulating qi and blood, and relieving arthralgia and pain. Can be widely used for internal medicine, surgery, gynecology, pediatrics and ophthalmology, and has special effects on mastitis, prostatitis, scapulohumeral periarthritis, pelvic inflammatory disease, cervical spondylosis, diabetes, etc. Secondly, moxibustion has the unique health preserving and health care functions. Moxibustion has been used for preventing diseases and prolonging life, and has a history of thousands of years in China. Huangdi's internal classic "Dafeng suohai, moxibustion Yi xi acupoint" is a health-care moxibustion method. The book of shou Zi records that holy Confucius is self-moxibustion without disease, and also refers to moxibustion for health promotion. Moxibustion anticancer research conducted by Japanese beard vine work and the like also shows that moxibustion can activate potential anticancer effects in skin tissues and play a role in treating cancers and resisting cancers.
The traditional Chinese medicine moxibustion is a natural therapy which mainly ignites moxa cones and moxa sticks made of folium artemisiae argyi and smokes and roasts acupuncture points of a human body to achieve health care and disease treatment. Moxa heat generated by moxa made of folium artemisiae argyi stimulates acupuncture points or specific positions on the body surface, and regulates the physiological and biochemical functions of human body disorder by exciting the activity of meridian qi, thereby achieving the purpose of preventing and treating diseases. The existing moxibustion derivative product is in a patch form and comprises a heat source layer and a medicine layer, wherein the heat source layer adopts chemical reaction to release heat, and the medicine in the medicine layer is mostly warm traditional Chinese medicine powder. Some products are also used in combination with essential oil of argy wormwood leaf.
The existing moxibustion patch products in the market are mainly formed by combining a chemical reaction heat source with a moxa bag, and the effect of moxa cannot be exerted due to the thermal effect, so that the using effect of the products is not obvious, and consumers lose confidence in the products.
Disclosure of Invention
In order to solve the defects of the prior art, the invention provides a novel moxibustion patch, which comprises a base layer, and a heat source layer, a Chinese herbal medicine essential oil layer, a Chinese herbal medicine powder layer, a moxa layer and an essential oil leading-in layer which are sequentially arranged on the base layer; the medicine powder in the Chinese herbal medicine powder layer and the medicine essential oil in the Chinese herbal medicine essential oil layer are prepared by the following method:
selecting a traditional Chinese medicine formula for symptomatic treatment, respectively taking the raw materials according to the formula, classifying the raw materials according to oil yielding properties, dividing the raw materials into two parts of Chinese herbal medicines which are easy to produce oil and Chinese herbal medicines which are difficult to produce oil, grinding the separated Chinese herbal medicines which are difficult to produce oil into powder to obtain medicine powder, extracting medicinal component essential oil from the separated Chinese herbal medicines which are easy to produce oil by adopting a microwave extraction technology, and wrapping the medicinal component essential oil by adopting β -cyclodextrin to obtain the medicine essential oil.
Preferably, the material of the folium artemisiae argyi essential oil import layer is import cotton made of hydrophobic oleophylic materials.
Preferably, the moxa in the moxa layer is high-quality moxa prepared from three years old folium artemisiae argyi serving as a raw material through airing, grinding and fine processing.
Preferably, the heat source materials in the heat source layer are iron powder, vermiculite, activated carbon, inorganic salt and water in a mass ratio of 4: 2: 1: 1: the reaction temperature of the mixture prepared by the ratio of 1 can reach 40-55 ℃.
Preferably, the traditional Chinese medicine formula for symptomatic treatment is a gynecological disease treatment formula, an osteoarticular treatment formula or a health-care health-preserving treatment formula.
The invention also provides a novel moxibustion patch combination, which comprises any one of the moxibustion patches and the matched folium artemisiae argyi essential oil.
Compared with the prior art, the invention has the beneficial effects that:
(1) the traditional moxibustion and the Chinese herbal medicines are combined, the Chinese herbal medicines in the prescription for the symptomatic treatment are classified according to the oil production property and are respectively prepared into medicine powder and medicine essential oil, and the medicine effect is better exerted by matching the medicine powder and the medicine essential oil.
(2) The invention adopts β -cyclodextrin as a wrapping material to wrap the medicine essential oil, under the condition of normal temperature storage, the Chinese herbal medicine essential oil layer and the Chinese herbal medicine powder layer are separated, when in use, under the action of a heat source, the wrapping material of the Chinese herbal medicine essential oil layer is heated and melted, the medicine essential oil of the Chinese herbal medicine essential oil layer is mixed with the medicine of the Chinese herbal medicine powder layer to exert the medicine effect together, the use of β -cyclodextrin not only solves the storage problem of the Chinese herbal medicine essential oil, but also plays a slow release role in the exertion of the medicine effect, and compared with the existing product, the effect of the moxibustion patch is greatly improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural view of a moxibustion patch provided in an embodiment of the present invention.
Detailed Description
In order to make the technical solutions of the present invention better understood and enable those skilled in the art to practice the present invention, the following embodiments are further described, but the present invention is not limited to the following embodiments.
Unless otherwise defined, all terms of art used hereinafter have the same meaning as commonly understood by one of ordinary skill in the art. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the scope of the present invention. Unless otherwise specifically stated, the various starting materials, reagents, instruments and equipment used in the following examples of the present invention are either commercially available or prepared by conventional methods.
The following is an example of the present invention, which is a formula of a Chinese medicine for treating gynecological diseases.
Example 1
A moxibustion patch for treating gynecological diseases is specifically shown in figure 1, and comprises a base layer 1, and a heat source layer 2, a Chinese herbal medicine essential oil layer 3, a Chinese herbal medicine powder layer 4, a moxa layer 5 and an essential oil leading-in layer 6 which are sequentially arranged on the base layer 1.
The medicine powder in the Chinese herbal medicine powder layer 4 and the medicine essential oil in the Chinese herbal medicine essential oil layer 3 are prepared by the following method: selecting a traditional Chinese medicine formula for symptomatic treatment of gynecological diseases, wherein the traditional Chinese medicine formula specifically comprises 5 parts of turmeric, 5 parts of liquorice, 8 parts of cassia twig, 20 parts of angelica, 10 parts of divaricate saposhnikovia root, 5 parts of common fennel and 20 parts of myrrh; the formula of the traditional Chinese medicine is as follows: turmeric: promoting blood circulation, dredging channels, dispelling pathogenic wind, removing arthralgia, promoting qi circulation, and stopping bleeding; licorice root: invigorating spleen and qi, relieving spasm and pain, clearing away heat and toxic materials, and harmonizing the above materials; cassia twig: dispel cold, relieve exterior syndrome, warm and dredge channels and collaterals, promote yang and transform qi; chinese angelica: loosening bowel to relieve constipation, promoting blood circulation for removing blood stasis, regulating menstruation and relieving pain; radix Saposhnikoviae for dispelling pathogenic wind, relieving exterior syndrome, eliminating dampness, relieving pain, relieving spasm, and relieving itching; fennel: warming kidney, dispelling cold, relieving pain, regulating qi-flowing, and regulating stomach function; myrrh: promoting blood circulation, relieving pain, promoting detumescence, promoting granulation, dispelling blood stasis, and dispelling cold.
The raw materials of the formula are classified according to oil production properties, mainly according to whether the herbal medicines can volatilize oil or not, for example, the raw materials are divided into two parts of Chinese herbal medicines which can easily produce oil and Chinese herbal medicines which can not easily produce oil, wherein the Chinese herbal medicines which can not easily produce oil comprise turmeric, liquorice and cassia twig, and the Chinese herbal medicines which can easily produce oil comprise Chinese angelica, divaricate saposhnikovia root, common fennel fruit and myrrh, and the like, and the divided Chinese herbal medicines which can not easily produce oil are ground into powder to obtain medicinal powder, and the divided Chinese herbal medicines which can easily produce oil are extracted by adopting a microwave extraction technology to obtain medicinal component essential oil, and are wrapped by β -cyclodextrin to obtain the medicinal essential oil.
The heat source material in the heat source layer 2 of the moxibustion patch is a mixture of iron powder, vermiculite, activated carbon, inorganic salt and water in a mass ratio of 4: 2: 1: 1: 1, the reaction temperature can reach 40-55 ℃, the medicinal essential oil in the Chinese herbal medicine essential oil layer 3 is prepared by taking Chinese angelica, divaricate saposhnikovia root, common fennel and myrrh as raw materials, extracting medicinal component essential oil by a microwave extraction technology, wrapping the medicinal component essential oil by β -cyclodextrin, grinding and pulverizing the medicinal component essential oil, the medicinal powder in the Chinese herbal medicine powder layer 4 is prepared by taking turmeric, liquorice and cassia twig as raw materials, the moxa in the moxa layer 5 is high-quality moxa prepared by taking three years old folium artemisiae argyi as a raw material, airing, grinding and finely processing, and the material of the essential oil introduction layer 6 is introduction cotton of a hydrophobic and oleophilic.
The moxibustion patch is simple to use, and can be applied on related acupuncture points. Has effects in dredging meridian passage, promoting qi and blood circulations, eliminating dampness, expelling cold, and relieving swelling and stagnation.
Based on the same inventive concept, in order to further enhance the moxibustion treatment effect of the moxibustion patch, we also provide a combined product based on the moxibustion patch, and the product for treating gynecological diseases is taken as an example and is illustrated by examples.
Example 2
A moxibustion patch combination for treating gynecological diseases comprises the moxibustion patch provided in example 1 and folium artemisiae argyi essential oil used in matching, and is a matched product. The folium Artemisiae Argyi essential oil is bottled, and when in use, appropriate amount of the essential oil is applied on the essential oil introduction layer 6, and then applied on related acupuncture points.
Similarly, the moxibustion patch and the moxibustion combination provided by the invention can also be made into products with other treatment effects, such as osteoarthrosis and health care and health preservation, which are the same as the bone joint and the health care and health preservation in structure and using method as the embodiment 1 and the embodiment 2, and the difference is only in the difference of the traditional Chinese medicine formula for symptomatic treatment, and the corresponding traditional Chinese medicine formula for symptomatic treatment can be selected according to specific symptoms, and the traditional Chinese medicine formula is classified and processed by adopting the same method as the embodiment 1 to be made into the product.
The moxibustion patch and the moxibustion composition for the bone joints can perform moxibustion on a plurality of bone joints such as lumbosacral, knee, neck and shoulder of a human body, can warm channels and dredge collaterals, dispel cold and relieve pain, stretch muscles and bones, promote qi and blood circulation, nourish skin and muscles, relieve soreness and pain, repair strain and maintain joints. In addition, moxibustion can be applied to improve the function of patients with osteoarthropathy and need stable curative effect after the treatment. The moxibustion patch and the moxibustion composition can also be prepared into health care and health preserving products for moxibustion, health care and body building, and are not specifically discussed here.
Of course, the moxibustion patch and moxibustion patch combination provided by the invention are not limited to be made into the gynecological diseases, osteoarthrosis and/or health care and health preservation, and can also be made into other diseases which can be diagnosed and treated by moxibustion acupuncture points of a traditional Chinese medicine formula.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations. The above-mentioned embodiments are merely preferred embodiments for fully illustrating the present invention, and the scope of protection is not limited thereto. The equivalents and modifications of the present invention which may occur to those skilled in the art are within the scope of the present invention as defined by the appended claims.

Claims (3)

1. A moxibustion patch is characterized by comprising a base layer (1), and a heat source layer (2), a Chinese herbal medicine essential oil layer (3), a Chinese herbal medicine powder layer (4), a moxa layer (5) and an essential oil leading-in layer (6) which are sequentially arranged on the base layer (1);
the medicine powder in the Chinese herbal medicine powder layer (4) and the medicine essential oil in the Chinese herbal medicine essential oil layer (3) are prepared by the following method that a Chinese herbal medicine formula for symptomatic treatment is selected, raw materials are respectively taken according to the formula, the raw materials are classified according to the oil yielding property and are divided into two parts of Chinese herbal medicine which is easy to produce oil and Chinese herbal medicine which is difficult to produce oil, the divided Chinese herbal medicine which is difficult to produce oil is ground into powder to obtain medicine powder, the divided Chinese herbal medicine which is easy to produce oil is extracted by adopting a microwave extraction technology to obtain medicinal component essential oil, and the medicine essential oil is obtained after the medicine essential oil is wrapped by β -cyclodextrin;
the essential oil leading-in layer (6) is made of leading-in cotton of a hydrophobic oleophylic material;
the heat source materials in the heat source layer (2) are iron powder, vermiculite, activated carbon, inorganic salt and water in a mass ratio of 4: 2: 1: 1: 1 proportion of mixture;
the traditional Chinese medicine formula for symptomatic treatment is a gynecological disease treatment formula, a bone joint treatment formula or a health-care health-preserving treatment formula.
2. A moxibustion patch according to claim 1, characterized in that the moxa in the moxa layer (5) is high quality moxa made from three years old mugwort leaves as raw material by air-curing, grinding and fine-processing.
3. A moxibustion patch composition, which is characterized by comprising the moxibustion patch of claim 1 and folium Artemisiae Argyi essential oil used in combination.
CN201710699838.8A 2017-08-16 2017-08-16 Moxibustion patch and moxibustion patch combination Active CN107375252B (en)

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CN108096364A (en) * 2017-12-21 2018-06-01 苏州希尔盖森新材料有限公司 A kind of multifunctional heating patch
CN110680903B (en) * 2019-11-28 2021-08-31 李茂然 Agilawood moxibustion strip and preparation method thereof
CN218165609U (en) * 2021-09-01 2022-12-30 广州纽得赛生物科技有限公司 Moxibustion plaster
CN114272117A (en) * 2021-12-31 2022-04-05 华南理工大学 Functional moxibustion tablet and preparation method thereof

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KR20080095002A (en) * 2007-04-23 2008-10-28 배삼훈 Method for producing bamboo moxibustion for combustion, water solubility and powder patch using far infrared rays and anions

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CN205411636U (en) * 2015-12-04 2016-08-03 於爱华 Paste moxibustion
CN106038261A (en) * 2016-05-30 2016-10-26 陈颉 Spontaneous heating moxibustion patch
CN106039587A (en) * 2016-06-24 2016-10-26 湖北博康医药科技有限公司 Health preserving moxibustion patch
CN106619096A (en) * 2016-10-12 2017-05-10 厦门市滋然生物科技有限公司 Bian-stone therapy and artemisiae argyi moxibustion plaster and manufacturing method thereof

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KR20080095002A (en) * 2007-04-23 2008-10-28 배삼훈 Method for producing bamboo moxibustion for combustion, water solubility and powder patch using far infrared rays and anions

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