CN107362117A - A kind of compound additive used for cosmetic and preparation method thereof - Google Patents
A kind of compound additive used for cosmetic and preparation method thereof Download PDFInfo
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- CN107362117A CN107362117A CN201710786375.9A CN201710786375A CN107362117A CN 107362117 A CN107362117 A CN 107362117A CN 201710786375 A CN201710786375 A CN 201710786375A CN 107362117 A CN107362117 A CN 107362117A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of compound additive used for cosmetic, in parts by weight, it is made up of following components:40~55 parts of 5~15 parts of B family vitamin, 2~6 parts of vitamin C, 2~4 parts of citrin, 10~20 parts of butter berry extract, 5~15 parts of Chinese gooseberry berry extract, 5~12 parts of sour cherry extract, 3~8 parts of aloe extract, 1~5 part of forulic acid, 1~5 part of apple polyphenol, 2~6 parts of Fructus Broussonetiae extract, 2~6 parts of ursin, 1~5 part of ginkgo biloba p.e, 1~4 part of herba hedyotis diffusae extract, 20~30 parts of emulsifying agent, 10~20 parts of astringent and deionized water.Also disclose its preparation method.A kind of compound additive used for cosmetic provided by the invention, it during exclusive use, can continue, effectively strengthen skin resistance, effectively prevent oxidative damage, while skin can be repaired, improve scar, promote wound healing to restore.
Description
Technical field
The present invention relates to a kind of compound additive used for cosmetic and preparation method thereof, cosmetic additive agent technology is particularly belonged to
Field.
Background technology
Impaired skin, refers to the skin injury caused by the factors such as sensibiligen, bacterium and other various environmental stimulis, and produce
It is raw it is red, swell, itch, pain, inflammation, the symptom such as long small pox.The originals such as allergic, the long small pox inflammation for damaging and occurring on skin
Cause, there are many theoretic analyses, for example after anaphylactogen enters human body, some histocytes can be made to discharge histamine isoreactivity thing
Matter, these active materials can cause capillary permeability increase, red swelling of the skin, the symptoms such as pain of itching, so as to trigger skin sensitive
And itch.Such as interior free yl is excessive again, free radical attack cells film, makes that cell membrane is destroyed, serum antiprotease loses
Activity, lesioned gene cause the appearance and accumulation of cytometaplasia, cause the damage of human normal cell and tissue, so as to cause people
There is condition susceptible in body.And the reason for long small pox, is more relatively easy:Sebum secretion is hyperfunction, and pore is obstructed, skin secretion
Grease can not smoothly flow out, and keratoderma hardening, angling are excessive, block pore, bacteria breed, make red swelling of the skin inflammation etc.
Deng.How to prevent skin to be damaged, how to be repaired after skin is impaired, turn into the emphasis of skin research.In daily life, people
Skin is protected by cosmetics, repaired, in the prior art, cosmetics are in enhancing skin resistance, the impaired skin of reparation
It is upper that there are still the problems such as protection and therapeutic effect are insufficient, and therapeutic effect is not lasting.In order to solve the above problems, study a kind of new
Type compound additive used for cosmetic, it appears particularly necessary.
The content of the invention
To solve the deficiencies in the prior art, it is an object of the invention to provide a kind of compound additive used for cosmetic and its system
Preparation Method, it can continue, effectively strengthen skin resistance, the preparation method is simple to operate, easily realizes.
In order to realize above-mentioned target, the present invention adopts the following technical scheme that:
A kind of compound additive used for cosmetic, in parts by weight, is made up of following components:B family vitamin 5~15
Part, 2~6 parts of vitamin C, 2~4 parts of citrin, 10~20 parts of butter berry extract, Chinese gooseberry berry extract 5~15
Part, 5~12 parts of sour cherry extract, 3~8 parts of aloe extract, 1~5 part of forulic acid, 1~5 part of apple polyphenol, paper mulberry fruit
2~6 parts of seed extract, 2~6 parts of ursin, 1~5 part of ginkgo biloba p.e, 1~4 part of herba hedyotis diffusae extract, emulsifying agent
90~200 parts of 20~30 parts, 10~20 parts of astringent and deionized water.
Further, aforesaid cosmetic product compound additive, in parts by weight, it is made up of following components:The dimension life of B races
8~15 parts of element, 2~6 parts of vitamin C, 2~4 parts of citrin, 12~20 parts of butter berry extract, the extraction of Chinese gooseberry fruit
7~15 parts of thing, 8~12 parts of sour cherry extract, 3~8 parts of aloe extract, 1~5 part of forulic acid, apple polyphenol 1~5
Part, 2~6 parts of Fructus Broussonetiae extract, 2~6 parts of ursin, 1~5 part of ginkgo biloba p.e, 1~4 part of herba hedyotis diffusae extract,
120~200 parts of 24~30 parts of emulsifying agent, 13~20 parts of astringent and deionized water.
Preferably, aforesaid cosmetic product compound additive, in parts by weight, it is made up of following components:B family vitamin
9 parts, 3 parts of vitamin C, 3 parts of citrin, 18 parts of butter berry extract, 11 parts of Chinese gooseberry berry extract, the sour cherry in Europe
10 parts of peach extract, 6 parts of aloe extract, 3 parts of forulic acid, 2.5 parts of apple polyphenol, 4.5 parts of Fructus Broussonetiae extract, ursin 4
Part, 3.5 parts of ginkgo biloba p.e, 2.5 parts of herba hedyotis diffusae extract, 27 parts of emulsifying agent, 16 parts of astringent and deionized water 160
Part.
In aforesaid cosmetic product compound additive, B family vitamin is vitamin B3, vitamin B5, orotic acid or dimension life
Two or three in plain B2.
In aforesaid cosmetic product compound additive, emulsifying agent is polyoxyethylene fatty acid, polyoxyethylene oxypropylene oleate
Or tetraethylene glycol monolaurate.
In aforesaid cosmetic product compound additive, astringent is citric acid.
A kind of preparation method of compound additive used for cosmetic, comprises the following steps:(1) by measure B family vitamin, dimension give birth to
Plain C, citrin, aloe extract, forulic acid, apple polyphenol, ursin and herba hedyotis diffusae extract, addition 30%~
The deionized water of 45% amount, under the conditions of 35 DEG C~45 DEG C, 15min~25min is stirred, it is standby to obtain mixture A;(2) according to quantity
Take butter berry extract, Chinese gooseberry berry extract, sour cherry extract, Fructus Broussonetiae extract, ginkgo biloba p.e,
The deionized water of emulsifying agent, astringent and 40%~50% amount, after first 30~40min of ultrasonic vibration, 70 DEG C~80 DEG C are heated to,
1~2h is stirred, 55 DEG C~65 DEG C is then cooled to and adds mixture A and remaining deionized water, continue 2~3h of stirring, cool
To 40 DEG C, after stirring 30min under the conditions of 1500~2000r/min, produce.
Preferably, the preparation method of aforesaid cosmetic product compound additive, comprises the following steps:(1) by measure B races dimension life
Element, vitamin C, citrin, aloe extract, forulic acid, apple polyphenol, ursin and herba hedyotis diffusae extract, add
The deionized water of 40% amount, under the conditions of 40 DEG C, 20min is stirred, it is standby to obtain mixture A;(2) by measure butter fruit extraction
Thing, Chinese gooseberry berry extract, sour cherry extract, Fructus Broussonetiae extract, ginkgo biloba p.e, emulsifying agent, convergence
Agent and the deionized water of 42% amount, after first ultrasonic vibration 35min, 75 DEG C are heated to, 1.5h is stirred, is then cooled to 60 DEG C of additions
Mixture A and remaining deionized water, continue to stir 2.5h, be cooled to 40 DEG C, after stirring 30min under the conditions of 1800r/min,
Produce.
The present invention is advantageous in that:A kind of compound additive used for cosmetic provided by the invention, during exclusive use, energy
It is enough to continue, effectively strengthen skin resistance, oxidative damage is effectively prevented, while skin can be repaired, improve scar, promote wound
Healing is restored.The compound additive of the present invention can absorb ultraviolet, have moment for the impaired skin of exposure under ultraviolet light
Fill up, the effect of maintenance, while free radical can be suppressed, suppress B16 cell, effectively prevent chloasma.The present invention's is compound
Additive, there is good performance of keeping humidity, skin moisture can be pinned, lift moisture content of skin, suppress wrinkle generation, at the same it is simultaneous
There is the effect of anti-aging.The present invention additive integrate multivitamin, fruit extract and Chinese medicinal material extract, it is each effectively into
Point influence each other, collective effect, effectively improve the analgesia of additive, antibacterial, anti-inflammatory, the effect for nursing skin.The present invention's
Compound additive is combined with other components, can strengthen the gas permeability and permeability of final cosmetic product, improves final products
Analgesia, anti-inflammatory effects so that final products have excellent crease-resistant, anti-aging characteristic.
Embodiment
The present invention is further introduced below in conjunction with specific embodiment.
Agents useful for same is commercially available prod in the present invention.
Embodiment 1
A kind of compound additive used for cosmetic, in parts by weight, is made up of following components:5 parts of B family vitamin, dimension
Raw plain 2 parts of C, 2 parts of citrin, 10 parts of butter berry extract, 5 parts of Chinese gooseberry berry extract, sour cherry extract
5 parts, 3 parts of aloe extract, 1 part of forulic acid, 1 part of apple polyphenol, 2 parts of Fructus Broussonetiae extract, 2 parts of ursin, ginkgo leaf extraction
90 parts of 1 part of thing, 1 part of herba hedyotis diffusae extract, 20 parts of emulsifying agent, 10 parts of astringent and deionized water.B family vitamin is given birth to for dimension
Plain B3 and vitamin B5.Emulsifying agent is polyoxyethylene fatty acid.Astringent is citric acid.
Embodiment 2
A kind of compound additive used for cosmetic, in parts by weight, is made up of following components:15 parts of B family vitamin, dimension
Raw plain 6 parts of C, 4 parts of citrin, 20 parts of butter berry extract, 15 parts of Chinese gooseberry berry extract, sour cherry extraction
12 parts of thing, 8 parts of aloe extract, 5 parts of forulic acid, 5 parts of apple polyphenol, 6 parts of Fructus Broussonetiae extract, 6 parts of ursin, ginkgo leaf carry
Take 200 parts of 5 parts of thing, 4 parts of herba hedyotis diffusae extract, 30 parts of emulsifying agent, 20 parts of astringent and deionized water.B family vitamin is
Vitamin B3 and orotic acid.Emulsifying agent is polyoxyethylene oxypropylene oleate.Astringent is citric acid.
Embodiment 3
A kind of compound additive used for cosmetic, in parts by weight, is made up of following components:8 parts of B family vitamin, dimension
Raw plain 4 parts of C, 3.5 parts of citrin, 12 parts of butter berry extract, 7 parts of Chinese gooseberry berry extract, sour cherry extraction
8 parts of thing, 7 parts of aloe extract, 4 parts of forulic acid, 3 parts of apple polyphenol, 3 parts of Fructus Broussonetiae extract, 5 parts of ursin, ginkgo leaf carry
Take 120 parts of 2 parts of thing, 3 parts of herba hedyotis diffusae extract, 24 parts of emulsifying agent, 13 parts of astringent and deionized water.B family vitamin is
Vitamin B3, vitamin B5 and vitamin B2.Emulsifying agent is tetraethylene glycol monolaurate.Astringent is citric acid.
Embodiment 4
A kind of compound additive used for cosmetic, in parts by weight, is made up of following components:12 parts of B family vitamin, dimension
Raw plain 5 parts of C, 2.5 parts of citrin, 15 parts of butter berry extract, 10 parts of Chinese gooseberry berry extract, sour cherry carry
Take 9 parts of thing, 5 parts of aloe extract, 2 parts of forulic acid, 4 parts of apple polyphenol, 5 parts of Fructus Broussonetiae extract, 3.5 parts of ursin, ginkgo
150 parts of 4 parts of leaf extract, 3.7 parts of herba hedyotis diffusae extract, 25 parts of emulsifying agent, 15 parts of astringent and deionized water.B races tie up
Raw element is vitamin B5 and vitamin B2.Emulsifying agent is polyoxyethylene fatty acid.Astringent is citric acid.
Embodiment 5
A kind of compound additive used for cosmetic, in parts by weight, is made up of following components:9 parts of B family vitamin, dimension
Raw plain 3 parts of C, 3 parts of citrin, 18 parts of butter berry extract, 11 parts of Chinese gooseberry berry extract, sour cherry extraction
10 parts of thing, 6 parts of aloe extract, 3 parts of forulic acid, 2.5 parts of apple polyphenol, 4.5 parts of Fructus Broussonetiae extract, 4 parts of ursin, ginkgo
160 parts of 3.5 parts of leaf extract, 2.5 parts of herba hedyotis diffusae extract, 27 parts of emulsifying agent, 16 parts of astringent and deionized water.B races
Vitamin is vitamin B5 and orotic acid.Emulsifying agent is tetraethylene glycol monolaurate.Astringent is citric acid.
Embodiment 1~5 is prepared by method in embodiment 6~8.
Embodiment 6
A kind of preparation method of compound additive used for cosmetic, comprises the following steps:(1) by measure B family vitamin, dimension give birth to
Plain C, citrin, aloe extract, forulic acid, apple polyphenol, ursin and herba hedyotis diffusae extract, add 30% amount
Deionized water, under the conditions of 35 DEG C, 15min is stirred, it is standby to obtain mixture A;(2) by measuring butter fruit extract, Chinese Mi
Monkey peach berry extract, sour cherry extract, Fructus Broussonetiae extract, ginkgo biloba p.e, emulsifying agent, astringent and 40% amount
Deionized water, after first ultrasonic vibration 30min, be heated to 70 DEG C, stir 1h, be then cooled to 55 DEG C and add mixture A and surplus
Remaining deionized water, continue to stir 2h, be cooled to 40 DEG C, after stirring 30min under the conditions of 1500r/min, produce.
Embodiment 7
A kind of preparation method of compound additive used for cosmetic, comprises the following steps:(1) by measure B family vitamin, dimension give birth to
Plain C, citrin, aloe extract, forulic acid, apple polyphenol, ursin and herba hedyotis diffusae extract, add 45% amount
Deionized water, under the conditions of 45 DEG C, 25min is stirred, it is standby to obtain mixture A;(2) by measuring butter fruit extract, Chinese Mi
Monkey peach berry extract, sour cherry extract, Fructus Broussonetiae extract, ginkgo biloba p.e, emulsifying agent, astringent and 50% amount
Deionized water, after first ultrasonic vibration 40min, be heated to 80 DEG C, stir 2h, be then cooled to 65 DEG C and add mixture A and surplus
Remaining deionized water, continue to stir 3h, be cooled to 40 DEG C, after stirring 30min under the conditions of 2000r/min, produce.
Embodiment 8
A kind of preparation method of compound additive used for cosmetic, comprises the following steps:(1) by measure B family vitamin, dimension give birth to
Plain C, citrin, aloe extract, forulic acid, apple polyphenol, ursin and herba hedyotis diffusae extract, add 40% amount
Deionized water, under the conditions of 40 DEG C, 20min is stirred, it is standby to obtain mixture A;(2) by measuring butter fruit extract, Chinese Mi
Monkey peach berry extract, sour cherry extract, Fructus Broussonetiae extract, ginkgo biloba p.e, emulsifying agent, astringent and 42% amount
Deionized water, after first ultrasonic vibration 35min, be heated to 75 DEG C, stir 1.5h, be then cooled to 60 DEG C add mixture A and
Remaining deionized water, continue to stir 2.5h, be cooled to 40 DEG C, after stirring 30min under the conditions of 1800r/min, produce.
A series of experiments is carried out to compound additive used for cosmetic in embodiment 1~5, concrete outcome is analyzed as follows.
1st, radicals scavenging is tested
The product of Example 1~5,6 repetitions are set, kit is determined according to Hydroxyl radical-scavenging ability respectively, surpasses
Oxygen anion Scavenging activity kit is measured.Experimental result is as shown in table 1 below.
Table 1
Sample | Scavenging action to hydroxyl free radical (%) | Superoxide anion free radical clearance rate (%) |
Embodiment 1 | 92.27 | 86.34 |
Embodiment 2 | 90.60 | 83.09 |
Embodiment 3 | 90.89 | 84.78 |
Embodiment 4 | 91.10 | 88.56 |
Embodiment 5 | 92.71 | 88.10 |
As shown in Table 1, product of the invention can effectively eliminate free radical.
2nd, the experiment of TYR enzyme enzyme is suppressed
Product in embodiments of the invention 1~5 is taken, 0.15% DOPA solution is added, after being sufficiently mixed, under the conditions of 30 DEG C
After being incubated 15min, 300 μ/mL TYR enzyme solution is added, continues to be incubated 15min, takes out extinction of the measure at 475nm
Value.As a result show skin care item of the present invention to the average inhibition of TYR enzyme up to more than 89%.Show the product energy of the present invention
Enough suppress the generation of melanin, prevent chloasma from generating.
3rd, performance of keeping humidity is tested
3.1st, short-term performance of keeping humidity
Test environment temperature is 1 DEG C of 25 scholar, and humidity is 50 ± 5%, and carries out real-time dynamic monitoring.On a voluntary basis
25~55 years old healthy test volunteer 50 is have selected, test position skin is without exception and without obvious scar or damage.Examination
Before testing, test volunteer needs to clean both hands and forearm, with dry face tissue wiped clean, is then testing volunteer's both hands hand
8 test points are chosen on the inside of the back of the body, forearm altogether and carry out test zone mark.Test point region area is 3x3cm2.Each test point
It is separated by 1cm.Tested using moisture of skin tester, each region parallel determination 5 times.The test point of every test volunteer
Region is respectively coated embodiment 1~5 and sets clear area (being not coated with any product).Before test, each test zone is first measured
Blank value.Then Example 1~5 presses 2.0 ± 0.lmg/cm2Sample size, sample is spread evenly across using latex finger cot
Test section.The skin in test point region and blank control region after 1 hour, 2 hours, 4 hours and 8h is measured after smearing respectively
Water content.The average value of each sample is calculated, the results are shown in Table 2.
Table 2
As shown in Table 2, sample has higher moisturizing rate in embodiment 1~5.Show the product moisturizing in short-term effect of the present invention
Fruit is good, duration length.
3.2nd, long-term performance of keeping humidity
Test environment temperature is 1 DEG C of 25 scholar, and humidity is 50 ± 5%, and carries out real-time dynamic monitoring.On a voluntary basis
25~55 years old healthy test volunteer 50 is have selected, test position skin is without exception and without obvious scar or damage.Examination
Before testing, test volunteer needs to clean both hands and forearm, with dry face tissue wiped clean, is then testing volunteer's both hands hand
8 test points are chosen on the inside of the back of the body, forearm altogether and carry out test zone mark.Test point region area is 3x3cm2.Each test point
It is separated by 1cm.Tested using moisture of skin tester, each region parallel determination 5 times.The test point of every test volunteer
Region is respectively coated embodiment 1~6 and sets clear area (being not coated with any product).Before test, each test zone is first measured
Blank value.Then Example 1~6 presses 2.0 ± 0.lmg/cm2Sample size, sample is spread evenly across using latex finger cot
Test section.Coating daily is once.Test zone and the moisture content of skin in blank control region after determining again 4 weeks and 8 weeks.Calculate each
The average value of sample, the results are shown in Table 3.
Table 3
As shown in Table 3, sample has higher moisturizing rate in embodiment 1~5.Show that the product of long-term use of present invention can
To be effectively improved the water content of skin.
4th, radiation proof is tested
(1) embodiment of the present invention 1~5 is taken, adds the test fluid that deionized water is configured to 0.025g/mL;With deionized water
As blank control group.Successively in UV A areas 400nm, 380nm, 360nm, 340nm, 320nm, UVB areas 320nm, 300nm,
280nm, UVC area 280nm, 260nm, 246nm, 240nm, 220nm, 200nm, determine the light transmittance of each test liquid, parallel determination 5
Secondary (n=5), according to formula A%=100%-T%, calculate average absorption ratio.As a result show:Embodiments of the invention 1~5 are flat
Equal absorptivity more than 93%, wherein, the absorptivity of embodiment 5 is more than 98%.Purple can be prevented by showing the product of the present invention
Skin is encroached in outside line, prevents skin from being tanned severely by sunlight.
(2) healthy mice is chosen, setting area is 2cm × 2cm irradiation area respectively, is respectively coated in embodiment 1~5
Product is not coated by any sample as blank group, coating commercially available prod is as a control group as sample sets.Carry out ultraviolet irradiation
20min, UV-irradiating portion skin is then taken, prepare skin histology homogenate, detect MDA, SOD, GSH-Px, CAT, Hyp water
It is flat.As a result show, sample sets indices are above control group and blank group, show there is good radiation-proof effect.Especially
It is the sample of embodiment 5, indices are above similar sample.
5th, Consumer's Experience
Control group uses commercially available prod, once in the morning and once at night, is used continuously 2 months.The product of the sample group present invention (is implemented
Example), once in the morning and once at night, it is used continuously 2 months.Before use, using being observed after 2 months, comparative evaluation's wrinkle, improve scar
Situation.Evaluation criterion is:4 grades improve and (improve 76%~100%), and 3 grades improve and (improve 51%~75%), and 2 grades of improvement (change
Kind 26%~50%), 1 grade improves and (improves 1%-25%), no improvement;+ 2 grades of improvement rates of total improvement effective percentage=1 grade of improvement rate+
+ 4 grades of improvement rates of 3 grades of improvement rates).As a result it is as shown in table 4.
Table 4
As shown in Table 4, product of the present invention is obvious to the improvement result of wrinkle, can effectively repair skin, improves scar.
Claims (8)
- A kind of 1. compound additive used for cosmetic, it is characterised in that:In parts by weight, it is made up of following components:The dimension life of B races 5~15 parts of element, 2~6 parts of vitamin C, 2~4 parts of citrin, 10~20 parts of butter berry extract, the extraction of Chinese gooseberry fruit 5~15 parts of thing, 5~12 parts of sour cherry extract, 3~8 parts of aloe extract, 1~5 part of forulic acid, apple polyphenol 1~5 Part, 2~6 parts of Fructus Broussonetiae extract, 2~6 parts of ursin, 1~5 part of ginkgo biloba p.e, 1~4 part of herba hedyotis diffusae extract, 90~200 parts of 20~30 parts of emulsifying agent, 10~20 parts of astringent and deionized water.
- 2. compound additive used for cosmetic according to claim 1, it is characterised in that:In parts by weight, by following Component is made:8~15 parts of B family vitamin, 2~6 parts of vitamin C, 2~4 parts of citrin, 12~20 parts of butter berry extract, 7~15 parts of Chinese gooseberry berry extract, 8~12 parts of sour cherry extract, 3~8 parts of aloe extract, forulic acid 1~5 Part, 1~5 part of apple polyphenol, 2~6 parts of Fructus Broussonetiae extract, 2~6 parts of ursin, 1~5 part of ginkgo biloba p.e, oldenlandia 120~200 parts of careless 1~4 part of extract, 24~30 parts of emulsifying agent, 13~20 parts of astringent and deionized water.
- 3. compound additive used for cosmetic according to claim 1, it is characterised in that:In parts by weight, by following Component is made:9 parts of B family vitamin, 3 parts of vitamin C, 3 parts of citrin, 18 parts of butter berry extract, Chinese gooseberry fruit carry 11 parts of thing, 10 parts of sour cherry extract, 6 parts of aloe extract, 3 parts of forulic acid, 2.5 parts of apple polyphenol, Paper mulberry Fruit is taken to carry Take 4.5 parts of thing, 4 parts of ursin, 3.5 parts of ginkgo biloba p.e, 2.5 parts of herba hedyotis diffusae extract, 27 parts of emulsifying agent, astringent 16 parts and 160 parts of deionized water.
- 4. compound additive used for cosmetic according to claim 1, it is characterised in that:The B family vitamin is vitamin Two or three in B3, vitamin B5, orotic acid or vitamin B2.
- 5. compound additive used for cosmetic according to claim 1, it is characterised in that:The emulsifying agent is polyoxyethylene fat Fat acid, polyoxyethylene oxypropylene oleate or tetraethylene glycol monolaurate.
- 6. compound additive used for cosmetic according to claim 1, it is characterised in that:The astringent is citric acid.
- 7. the preparation method of the compound additive used for cosmetic as described in any one of claim 1~6, it is characterised in that:Including Following steps:(1) by measuring B family vitamin, vitamin C, citrin, aloe extract, forulic acid, apple polyphenol, ursin And herba hedyotis diffusae extract, the deionized water of 30%~45% amount of addition, under the conditions of 35 DEG C~45 DEG C, stirring 15min~ 25min, it is standby to obtain mixture A;(2) by measure butter fruit extract, Chinese gooseberry berry extract, sour cherry extract Thing, Fructus Broussonetiae extract, ginkgo biloba p.e, emulsifying agent, the deionized water of astringent and 40%~50% amount, first ultrasonic vibration After 30~40min, 70 DEG C~80 DEG C are heated to, stirs 1~2h, 55 DEG C~65 DEG C is then cooled to and adds mixture A and residue Deionized water, continue 2~3h of stirring, be cooled to 40 DEG C, after stirring 30min under the conditions of 1500~2000r/min, produce.
- 8. the preparation method of compound additive used for cosmetic according to claim 7, it is characterised in that:Including following step Suddenly:(1) by measuring B family vitamin, vitamin C, citrin, aloe extract, forulic acid, apple polyphenol, ursin and white flower HERBA HEDYOTIS DIFFUSAE extract, the deionized water of 40% amount is added, under the conditions of 40 DEG C, stir 20min, it is standby to obtain mixture A;(2) Carried by butter fruit extract, Chinese gooseberry berry extract, sour cherry extract, Fructus Broussonetiae extract, ginkgo leaf is measured Take the deionized water of thing, emulsifying agent, astringent and 42% amount, after first ultrasonic vibration 35min, be heated to 75 DEG C, stir 1.5h, with After be cooled to 60 DEG C and add mixture A and remaining deionized water, continue to stir 2.5h, 40 DEG C be cooled to, in 1800r/min bars After stirring 30min under part, produce.
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Cited By (1)
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CN114288216A (en) * | 2021-12-16 | 2022-04-08 | 优颜皮肤科学研究(广州)有限公司 | Antioxidant and anti-saccharification composition and preparation method thereof |
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CN105362120A (en) * | 2015-10-22 | 2016-03-02 | 邹健 | Chinese herbal medicine cleansing milk having anti-aging effect and preparation method thereof |
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CN103405363A (en) * | 2013-07-29 | 2013-11-27 | 朱耀灯 | Sun-proof repair combination |
CN103462872A (en) * | 2013-09-26 | 2013-12-25 | 陈理敬 | Whitening moisturizing make-up lotion and preparation method thereof |
CN105362120A (en) * | 2015-10-22 | 2016-03-02 | 邹健 | Chinese herbal medicine cleansing milk having anti-aging effect and preparation method thereof |
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