CN107356776A - A kind of automatic bacterial vaginosis detector - Google Patents

A kind of automatic bacterial vaginosis detector Download PDF

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Publication number
CN107356776A
CN107356776A CN201710627629.2A CN201710627629A CN107356776A CN 107356776 A CN107356776 A CN 107356776A CN 201710627629 A CN201710627629 A CN 201710627629A CN 107356776 A CN107356776 A CN 107356776A
Authority
CN
China
Prior art keywords
detection
suction nozzle
sample
board
bacterial vaginosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710627629.2A
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Chinese (zh)
Inventor
林华青
王万春
陈章富
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhuhai DL Medical Biotech Co., Ltd.
Original Assignee
Zhuhai Deere Medical Equipment Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhuhai Deere Medical Equipment Research Institute Co Ltd filed Critical Zhuhai Deere Medical Equipment Research Institute Co Ltd
Priority to CN201710627629.2A priority Critical patent/CN107356776A/en
Publication of CN107356776A publication Critical patent/CN107356776A/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Abstract

The invention discloses a kind of automatic bacterial vaginosis detector, including shell and main frame, main frame is provided with laying out apparatus, sampler, detection means, retracting device and printing equipment, detection means includes rotating disk mechanism, first drive mechanism and detection module, first drive mechanism rotates for driving rotating disk mechanism, some detection boards are installed on rotating disk mechanism, reactive tank is provided with detection board, drop has detection liquid in reactive tank, chromogenic reaction occurs after sample contacts with the detection liquid in detection board, detection module includes being disposed therein the color sensor control circuit above a detection board.This detector realizes automatic sample, culture, detection, the full-automatic function that running stores are reclaimed, printed report is integrated by the laying out apparatus, sampler, detection means, retracting device and the printing equipment that are set on main frame, automaticity is high, detection efficiency is high, and operating personnel are not easily susceptible to infect.

Description

A kind of automatic bacterial vaginosis detector
Technical field
The present invention relates to technical field of medical instruments, more particularly to a kind of automatic bacterial vaginosis detector.
Background technology
Bacterial vaginosis BV (BV) is one of most common disease of gynaecology, and its pathogenic factor is mainly due to the normal bacterium of vagina Group is reduced, and some pathogenic anaerobic bacteria floras replace or its quantity exceedes vagina normal flora and caused, for example Gardnerella etc. is detested Oxygen bacterium corrodes vaginal cell, and anaerobic bacteria can produce tissue polyamines, and caused polyamine content is with the bacterial population in vagina into just Than, and normal women vagina is free of such material, therefore can diagnose BV by determining polyamines.
At present, the BV detection instruments of in the market are mainly BV quick detection kits, there is polyamine process, enzymology reaction, saliva Three kinds of main detection methods of liquid acid-enzyme hydrolysis method, the major function of such product are incubated with colorimetric, it is necessary to when being manually controlled Between and yin and yang attribute judge, it is cumbersome, and estimate subjective error and the manual bad timing of incubation time can be to testing result Cause necessarily to influence.
Now, BV detectors start to integrate sample-adding, temperature control, detection, report output full-automatic detector send out Exhibition, but existing BV detectors automaticity is low, and detection process is cumbersome, and detection efficiency is low, and operating personnel are vulnerable to infection.
The content of the invention
In order to overcome the above-mentioned deficiencies of the prior art, the invention provides a kind of automatic bacterial vaginosis detector, Integrate automatic sample, culture, detection, printed report, running stores recovery, automaticity is high, and detection efficiency is high, operator Member is not easily susceptible to infect.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of automatic bacterial vaginosis detector, including shell and main frame, the main frame are provided with laying out apparatus, taken Sampling device, detection means, retracting device and printing equipment, the laying out apparatus are used to place some sample tubes, the sampling Device is used to the sample in sample tube being transported in detection means, and the detection means detects to sample, the inspection Surveying device includes rotating disk mechanism, the first drive mechanism and detection module, and first drive mechanism turns for driving rotating disk mechanism It is dynamic, some detection boards are installed on the rotating disk mechanism, are provided with reactive tank on the detection board, drop has detection in reactive tank Liquid, chromogenic reaction occurs after sample contacts with the detection liquid in detection board, detection module includes being disposed therein an inspection Color sensor control circuit above drafting board card, the color sensor can read the color change in detection board and will As a result feed back in control circuit, the retracting device is used to reclaim the detection board that device detected after testing, the printing The testing result that device can draw detection module prints.
As the improvement of above-mentioned technical proposal, the rotating disk mechanism includes terminal pad and rotating disc, and the terminal pad rotates On a base, the base is fixed on main frame bottom, rotating disc be arranged on terminal pad upper end and with terminal pad together Rotate, circumferentially offer some necks, the neck both ends open on the rotating disc, the detection plate card is filled by clamping Put and be fastened in neck.
As the improvement of above-mentioned technical proposal, the retracting device includes the second drive mechanism, push rod and is arranged at rotation Recycling box on the outside of disk, the push rod are arranged at neck the inner and one end alignment wherein neck, and second drive mechanism can band Dynamic push rod is moved back and forth, and after board completion detection is detected, push rod will be detected in board push-in recycling box.
As the improvement of above-mentioned technical proposal, the rotating disc bottom is provided with heating plate, for detection board heating Insulation.
As the improvement of above-mentioned technical proposal, the laying out apparatus includes test tube case and the 3rd drive mechanism, the sample Test tube is positioned in test tube case, and the 3rd drive mechanism can drive test tube case is movable in main frame to be easy to staff to put Put sample tube.
As the improvement of above-mentioned technical proposal, the sampler includes sampling suction nozzle carrier, sampling suction nozzle releasing mechanism With the sampling suction nozzle for drawing the sample in sample tube, the sampling suction nozzle is previously positioned in a suction nozzle box, described to take Can be moved left and right under the driving of the 4th drive mechanism of the sample suction nozzle carrier at the top of main frame and can be in the 4th drive mechanism Moved up and down under the driving of five drive mechanisms to change sampling suction nozzle.
As the improvement of above-mentioned technical proposal, the sampling suction nozzle carrier includes suction pipe and drives suction pipe to draw the of sample Six drive mechanisms, the suction pipe include suction pipe our department and can be to underthrusts positioned at the insertion section of suction pipe our department lower end, the insertion section Enter and clamping samples suction nozzle.
As the improvement of above-mentioned technical proposal, the 6th drive mechanism includes piston rod and driving piston rod moves up and down Linear electric motors, in piston rod insertion suction pipe our department, sampling suction nozzle utilizes pressure change caused by piston rod movement to draw With release sample.
As the improvement of above-mentioned technical proposal, the sampling suction nozzle releasing mechanism includes the connection installed in outer casing inner wall Plate, breach is provided with the connecting plate outer rim, and the sampling suction nozzle can be tangled by breach in upward motion process and thus taken off From suction pipe, the connecting plate lower position is provided with accommodating case, and the accommodating case is used to receive the sampling suction nozzle for departing from suction pipe.
As the improvement of above-mentioned technical proposal, the accommodating case and suction nozzle box are both placed in a holder, the placement Box is moved forward and backward by the 7th drive mechanism in main frame to be easy to staff to place sampling suction nozzle and collects discarded sampling suction nozzle.
Beneficial effects of the present invention have:
This detector passes through the laying out apparatus, sampler, detection means, retracting device and the printing equipment that are set on main frame Automatic sample, culture, detection, the full-automatic function that running stores are reclaimed, printed report is integrated are realized, automaticity is high, Detection efficiency is high, and operating personnel are not easily susceptible to infect.
Brief description of the drawings
Below in conjunction with the accompanying drawings and specific embodiment the invention will be further described, wherein:
Fig. 1 is the structural representation of the embodiment of the present invention;
Fig. 2 is the internal structure schematic diagram of the embodiment of the present invention;
Fig. 3 is the partial structural diagram of the embodiment of the present invention;
Fig. 4 is the partial sectional view of the embodiment of the present invention.
Embodiment
Referring to Fig. 1, Fig. 2, Fig. 3 and Fig. 4, a kind of automatic bacterial vaginosis detector, including shell 1 and main frame, institute State main frame and be provided with laying out apparatus, sampler, detection means, retracting device and printing equipment 24, the laying out apparatus is used for Some sample tubes 2 are placed, the sampler is used to the sample in sample tube 2 being transported in detection means, the inspection The detection of the complete paired samples of device is surveyed, the detection means includes rotating disk mechanism, the first drive mechanism and detection module, and described the One drive mechanism is rotated for driving rotating disk mechanism, and some detection boards 3 are provided with the rotating disk mechanism, detects and is opened on board There is reactive tank, four reactive tanks are opened up in the present embodiment, being dripped respectively inside four reactive tanks has detection liquid to detect sample Concentration of hydrogen peroxide, sialidase, leukocyte esterase and pH value, occur after sample contacts with the detection liquid in detection board Chromogenic reaction, the detection module are understood to the testing result for detecting board 3, and detection module includes being disposed therein an inspection The color sensor 28 and control circuit of the top of drafting board card 3, the color sensor 28 can read the color in detection board 3 Change and feed back to result in control circuit, draw testing result, the retracting device is used to reclaim device after testing and detected The detection board 3 crossed, the testing result that the printing equipment 24 can draw detection module print.
The rotating disk mechanism includes terminal pad 5 and rotating disc 6, and terminal pad 5 is rotatably installed on a base 4, the base 4 Main frame bottom is fixed on, rotating disc 6 is arranged on the upper end of terminal pad 5 and as terminal pad 5 rotates together, first drive mechanism Including the first motor 9, driving gear 10 and driven gear 11, first motor 9 is arranged on main frame bottom, the driving gear 10 are fixed on the output shaft of the first motor 9, and the driven gear 11 is fixedly connected with terminal pad 5 and nibbled with driving gear 10 Close, the rotation of terminal pad 5 is driven by the rotation of the first motor 9, some necks, institute are circumferentially offered on the rotating disc 6 Neck both ends open is stated, the detection board 3 is fastened in neck by gripping mechanism 26, and the gripping mechanism includes being arranged on The compression plate of rotating disc upper end, compression plate lower end, which is located at neck top, is provided with elastic pressuring plate 27, and detection board sticks into neck Compressed afterwards by elastic pressuring plate 27, the retracting device includes the second drive mechanism, push rod 7 and is arranged at returning for the outside of rotating disc 6 Box 8 is received, the push rod 7 is arranged at neck the inner and one end alignment wherein neck, second drive mechanism can drive push rod 7 Move back and forth, after the completion detection of board 3 is detected, push rod 7 is pushed into board 3 is detected in recycling box 8, the bottom of rotating disc 6 Heating plate 25 is installed, for detecting the heating and thermal insulation of board 3.
The laying out apparatus includes the drive mechanism of test tube case 12 and the 3rd, and the sample tube 2 is positioned in test tube case 12, 3rd drive mechanism can drive test tube case 12 is movable in main frame to be easy to staff to place sample tube 2.
The sampler includes sampling suction nozzle carrier, sampling suction nozzle releasing mechanism and for drawing in sample tube 2 The sampling suction nozzle 13 of sample, the sampling suction nozzle 13 are previously positioned in a suction nozzle box 14, and the sampling suction nozzle carrier is in main frame It can be moved left and right under the driving of 4th drive mechanism at top and can be in the driving of the 5th drive mechanism in the 4th drive mechanism Under move up and down and sample suction nozzle 13 to change, the sampling suction nozzle carrier includes suction pipe 15 and drives suction pipe 15 to draw the of sample Six drive mechanisms, the suction pipe 15 include suction pipe our department 16 and positioned at the insertion section 17 of the lower end of suction pipe our department 16, the insertion sections 17 can be downwardly into simultaneously clamping sampling suction nozzle 13, and the 6th drive mechanism includes moving down on piston rod 18 and driving piston rod 18 Dynamic linear electric motors 19, the piston rod 18 are inserted in suction pipe our department 16, and sampling suction nozzle 13 is moved caused using piston rod 18 Pressure change is drawn and release sample, and the sampling suction nozzle releasing mechanism includes the connecting plate 20 installed in the inwall of shell 1, described Breach 21 is provided with the outer rim of connecting plate 20, the sampling suction nozzle 13 can be tangled by breach 21 in upward motion process and thus taken off From suction pipe 15, the lower position of connecting plate 20 is provided with accommodating case 22, and the accommodating case 22, which is used to receive, departs from suction pipe 15 Sampling suction nozzle 13, the accommodating case 22 and suction nozzle box 14 be both placed in a holder 23, and the holder 23 passes through the 7th Drive mechanism moves forward and backward in main frame to be easy to staff to place sampling suction nozzle 13 and collects discarded sampling suction nozzle 13, described outer Test tube case baffle plate 30 and holder baffle plate 29 test tube case 12, the holder with being arranged in main frame respectively are set on the front end face of shell 1 23 is corresponding, it is necessary to raise test tube case baffle plate and holder baffle plate when collecting test tube case and holder, the front end face of shell 1 On be additionally provided with detection plate block plate 31 and display screen 32, operating personnel raise detection plate block plate 31 and will detected when placing board Board 3 is pushed into neck.
The workflow of the present invention:Sample tube 2 and detection board 3 are respectively put into test tube case 12 and neck by operating personnel Afterwards, sampling suction nozzle carrier moves downward after being moved to the top of suction nozzle box 14, the insertion of the insertion section 17 sampling suction nozzle 13 of suction pipe 15, so Suction nozzle carrier is sampled afterwards to be moved to the top of test tube case 12 with sampling suction nozzle 13 and draw sample downwards, then samples suction nozzle carrier It is moved to behind the top of rotating disc 6 and moves down with sampling suction nozzle 13 and sample is discharged on detection board 3, discharged sample Sampling suction nozzle 13 is moved to the lower section of connecting plate 20 and departs from sampling suction nozzle carrier during rising afterwards, later falls into accommodating case In 22, an entire flow of sampling and setting-out is completed, next repeats above-mentioned action and will each detect board 3 to add sample This, incubates through heating after a while, and detection module obtains result and result is printed and is shown on display screen 32, The detection board 3 detected is pushed into collection box 8 by push rod 7, completes whole testing process.
It is described above, the simply better embodiment of the present invention, but the present invention is not limited to above-described embodiment, as long as It reaches the technique effect of the present invention with any same or similar means, should all belong to protection scope of the present invention.

Claims (10)

1. a kind of automatic bacterial vaginosis detector, including shell (1) and main frame, it is characterised in that:Set on the main frame There are laying out apparatus, sampler, detection means, retracting device and a printing equipment (24), the laying out apparatus is used to placing some Sample tube (2), the sampler are used to the sample in sample tube (2) being transported in detection means, the detection dress Put and sample is detected, the detection means includes rotating disk mechanism, the first drive mechanism and detection module, first driving Mechanism is rotated for driving rotating disk mechanism, and some detection boards (3), the detection board (3) are provided with the rotating disk mechanism On be provided with reactive tank, drop has detection liquid in reactive tank, when colour developing occurs with detecting after the detection liquid in board (3) contacts in sample Reaction, detection module include being disposed therein color sensor (28) control circuit above a detection board (3), the color Sensor (28) can read the color change in detection board (3) and feed back to result in control circuit, the recovery dress Put for reclaiming the detection board (3) that device detected after testing, the inspection that the printing equipment (24) can draw detection module Result is surveyed to print.
A kind of 2. automatic bacterial vaginosis detector according to claim 1, it is characterised in that:The rotating disk mechanism Including terminal pad (5) and rotating disc (6), the terminal pad (5) is rotatably installed on a base (4), and the base (4) is fixed on Main frame bottom, rotating disc (6) is arranged on terminal pad (5) upper end and as terminal pad (5) rotates together, on the rotating disc (6) Some necks, the neck both ends open are circumferentially offered, the detection board (3) is fastened on card by gripping mechanism (26) In groove.
A kind of 3. automatic bacterial vaginosis detector according to claim 2, it is characterised in that:The retracting device Including the second drive mechanism, push rod (7) and rotating disc (6) outside recycling box (8) is arranged at, the push rod (7) is arranged at neck Inner and one end alignment wherein neck, second drive mechanism can drive push rod (7) to move back and forth, when detection board (3) After completing detection, push rod (7) will be detected in board (3) push-in recycling box (8).
A kind of 4. automatic bacterial vaginosis detector according to claim 2, it is characterised in that:The rotating disc (6) bottom is provided with heating plate (25), for detecting board (3) heating and thermal insulation.
A kind of 5. automatic bacterial vaginosis detector according to claim 1, it is characterised in that:The laying out apparatus Including test tube case (12) and the 3rd drive mechanism, the sample tube (2) is positioned in test tube case (12), the 3rd driving machine Structure can drive test tube case (12) is movable in main frame to be easy to staff to place sample tube (2).
A kind of 6. automatic bacterial vaginosis detector according to claim 1, it is characterised in that:The sampler Including sampling suction nozzle carrier, sampling suction nozzle releasing mechanism and sampling suction nozzle (13) for drawing the sample in sample tube (2), The sampling suction nozzle (13) is previously positioned in a suction nozzle box (14), fourth driving of the sampling suction nozzle carrier at the top of main frame It can move left and right and can be moved up and down under the driving of the 5th drive mechanism in the 4th drive mechanism with more under the driving of mechanism Exchange sample suction nozzle (13) for.
A kind of 7. automatic bacterial vaginosis detector according to claim 6, it is characterised in that:The sampling suction nozzle Carrier includes suction pipe (15) and drives the 6th drive mechanism of suction pipe (15) absorption sample, and the suction pipe (15) includes suction pipe our department (16) and positioned at the insertion section (17) of suction pipe our department (16) lower end, the insertion section (17) can be downwardly into and clamping sampling suction nozzle (13)。
A kind of 8. automatic bacterial vaginosis detector according to claim 7, it is characterised in that:6th driving The linear electric motors (19) that mechanism includes piston rod (18) and drives piston rod (18) to move up and down, piston rod (18) insertion are inhaled In pipe our department (16), sampling suction nozzle (13) is drawn using pressure change caused by piston rod (18) motion and release sample.
A kind of 9. automatic bacterial vaginosis detector according to claim 6, it is characterised in that:The sampling suction nozzle Releasing mechanism includes the connecting plate (20) installed in shell (1) inwall, and breach (21), institute are provided with connecting plate (20) outer rim Stating sampling suction nozzle (13) can be tangled by breach (21) in upward motion process and thus depart from suction pipe (15), the connecting plate (20) lower position is provided with accommodating case (22), and the accommodating case (22) is used to receive the sampling suction nozzle for departing from suction pipe (15) (13)。
A kind of 10. automatic bacterial vaginosis detector according to claim 9, it is characterised in that:The accommodating case (22) it is both placed in suction nozzle box (14) in a holder (23), the holder (23) is by the 7th drive mechanism in main frame It is movable to be easy to staff to place sampling suction nozzle (13) and collect discarded sampling suction nozzle (13).
CN201710627629.2A 2017-07-28 2017-07-28 A kind of automatic bacterial vaginosis detector Pending CN107356776A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710627629.2A CN107356776A (en) 2017-07-28 2017-07-28 A kind of automatic bacterial vaginosis detector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710627629.2A CN107356776A (en) 2017-07-28 2017-07-28 A kind of automatic bacterial vaginosis detector

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Publication Number Publication Date
CN107356776A true CN107356776A (en) 2017-11-17

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CN201710627629.2A Pending CN107356776A (en) 2017-07-28 2017-07-28 A kind of automatic bacterial vaginosis detector

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110325842A (en) * 2017-11-30 2019-10-11 柯正浩 Screening test paper reads system
CN112748106A (en) * 2021-02-01 2021-05-04 珠海市人民医院 Acid-base detection system for endocrine
WO2022217397A1 (en) * 2021-04-12 2022-10-20 苏州鼎实医疗科技有限公司 Fully automated immunoassay analyzer convenient for feeding and discharging

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CN205193083U (en) * 2015-12-01 2016-04-27 广州鸿琪光学仪器科技有限公司 Detecting analyzer is united to bacillary vaginopathy of full automatization
CN105548132A (en) * 2015-11-23 2016-05-04 王治才 Automatic rotary-disc type fluorescence detector
CN106248923A (en) * 2016-08-31 2016-12-21 上海贝西生物科技有限公司 A kind of fluorescence immunoassay device

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Publication number Priority date Publication date Assignee Title
CN103728460A (en) * 2014-01-17 2014-04-16 广州鸿琪光学仪器科技有限公司 Automatic bacterial vaginosis detector
CN104535782A (en) * 2014-12-29 2015-04-22 基蛋生物科技股份有限公司 Full-automatic immuno-fluorescence quantitative analysis device and implementation method
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110325842A (en) * 2017-11-30 2019-10-11 柯正浩 Screening test paper reads system
CN112748106A (en) * 2021-02-01 2021-05-04 珠海市人民医院 Acid-base detection system for endocrine
WO2022217397A1 (en) * 2021-04-12 2022-10-20 苏州鼎实医疗科技有限公司 Fully automated immunoassay analyzer convenient for feeding and discharging

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