CN107353316B - 用于治疗神经变性疾病的尿苷二磷酸衍生物、组合物和方法 - Google Patents

用于治疗神经变性疾病的尿苷二磷酸衍生物、组合物和方法 Download PDF

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CN107353316B
CN107353316B CN201710598982.2A CN201710598982A CN107353316B CN 107353316 B CN107353316 B CN 107353316B CN 201710598982 A CN201710598982 A CN 201710598982A CN 107353316 B CN107353316 B CN 107353316B
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pain
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CN107353316A (zh
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P·海登
李劲波
董静慧
斯蒂芬·莫斯
拉奎尔·雷维拉-桑切斯
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Tufts University
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    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
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    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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CN201710598982.2A 2011-09-30 2012-09-28 用于治疗神经变性疾病的尿苷二磷酸衍生物、组合物和方法 Expired - Fee Related CN107353316B (zh)

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EP2968385B1 (en) * 2013-03-13 2018-05-23 Tufts University Uridine nucleoside derivatives, compositions and methods of use
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KR20210028190A (ko) * 2018-06-14 2021-03-11 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 글리코실화 장애를 치료하는 방법 및 물질
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EP2760858A1 (en) 2014-08-06
US20210347807A1 (en) 2021-11-11
IL231787A (en) 2017-05-29
IL231787A0 (en) 2014-05-28
US20130252919A1 (en) 2013-09-26
US20160318968A1 (en) 2016-11-03
JP6162125B2 (ja) 2017-07-12
US11072627B2 (en) 2021-07-27
US9227993B2 (en) 2016-01-05
IN2014CN03043A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-07-03
CN103906745A (zh) 2014-07-02
CA2850367C (en) 2021-06-01
US20190309009A1 (en) 2019-10-10
CA2850367A1 (en) 2013-04-04
US20150045319A1 (en) 2015-02-12
US8598141B2 (en) 2013-12-03
JP2014528418A (ja) 2014-10-27
EP2760858B1 (en) 2018-08-08
CN103906745B (zh) 2017-08-25
AU2012315671B2 (en) 2017-07-20
US8785620B2 (en) 2014-07-22
CN107353316A (zh) 2017-11-17
WO2013049686A1 (en) 2013-04-04

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