CN107349370A - A kind of external medicine composition and its application for being used to treat vaginitis - Google Patents
A kind of external medicine composition and its application for being used to treat vaginitis Download PDFInfo
- Publication number
- CN107349370A CN107349370A CN201710656509.5A CN201710656509A CN107349370A CN 107349370 A CN107349370 A CN 107349370A CN 201710656509 A CN201710656509 A CN 201710656509A CN 107349370 A CN107349370 A CN 107349370A
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- medicine composition
- vaginitis
- chinese medicine
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Abstract
The invention discloses a kind of external medicine composition and its application for being used to treat vaginitis, belong to pharmaceutical technology field.Described external medicine composition is made up of each bulk drug of following parts by weight：25~35 parts of dandelion, 25~35 parts of Lappula echinata, flea stop 25~35 parts, 25~35 parts of kuh-seng, 15~25 parts of the tuber of stemona, 15~25 parts of Chinese violet, 25~35 parts of frutus cnidii, 5~15 parts of pericarpium zanthoxyli, 10~20 parts of the root of Chinese clematis, 25~35 parts of golden cypress and windproof 5~15 parts.The present invention solves the Western medicine that vaginitis is treated present in prior art and has that drug resistance, treatment cycle are long and side effect is big, and Chinese medicine therapeutic effect unobvious, antipruritic effect is poor, can not suppress the problems such as human papilloma virus infection.In addition, the invention also provides the oral traditional Chinese medicine composition that the external medicine composition described in a kind of cooperation uses, the two synergy can be antipruritic with clearing heat and promoting diuresis, desinsection, has good therapeutic action to vaginitis, especially monilial vaginitis.
Description
Technical field
The present invention relates to a kind of external medicine composition and its application for being used to treat vaginitis.The invention belongs to medical skill
Art field.
Background technology
Female genital tract infection is that one group of infectious diseases in female reproductive system occurs, including sexually transmitted disease, interior
Source property flora imbalance (such as bacterial vaginosis BV) and hospital-acquired infection (caused by such as surgical instrument disinfection is improper), mainly by bacterium,
The common causatives such as virus, Chlamydia, fungi, trichomonad cause.The infection of vulva, vagina and uterine neck is also known as Lower genital tract sense
Dye, the LGTI related to sexually transmitted disease is mainly gonorrhoea, Between Non-gonococcal Cervicitis, trichomonas vaginitis, beads
Bacterium property vaginitis, bacterial vaginosis BV, genital herpes etc..
Especially vaginitis, vaginitis be due to pathogenic microorganism (including the microorganism such as mould, bacterium, trichomonad) infection and
Caused inflammatory reaction.Vaginitis can be divided into mould vaginosis (also known as Candidal Vaginosis), senile vahinitis, trichomonad
Property vaginitis, bacterial vaginosis BV etc..Various types of vaginitis have secretion to increase, are even with frequent micturition, urgent urination, the disease of odynuria
Shape, vulva have different degrees of itch, scorching hot or pain, and acute stage can be with heating.Although symptom is similar, inhomogeneity
Vaginitis (disease) medication of type but has very big difference.
The method for the treatment of vaginitis has a lot, such as：Physical therapy, medicinal treatment, tcm therapy or physical bond medicine
Thing therapy, Enema compress western medicine therapy, externally applied drug combination oral medicine therapy etc., and the treatment method of various vaginitis is all
Different.
At present, abuse of antibiotics turns into a serious social concern in the diagnosis and treatment of venereal disease.Easily using substantial amounts of anti-
Raw element, not only causes huge financial burden, and irregular medication, not only pathogen is not killed, on the contrary to patient
The flora imbalance of patient itself and pathogen is caused to create antagonism and give birth to the drug resistance of element, it is also gradual to the sensitiveness of Tri-Biocin
Reduce, so that some patients are invalid to conventional antibiosis extract for treating.For example general therapeutic colpitis medicine is Miconazole in Miconazole Suppository
(such as gynaecology Da Kening), Miconazole in Miconazole Suppository largely shorten the course for the treatment of compared with some other medicine.But nitric acid miaow
Health azoles bolt Reporting of harms is more common, cure rate is high, in-convenience in use, the course for the treatment of is relatively long, the menstrual period should not use.Make
The accidental allergic reaction in, majority is slighter, also local excitation, itch and burning heat sensation, especially when treating beginning, pelvic cavity convulsion
Contraction, nettle rash, skin rashes also have generation.Treatment bacterial vaginosis BV typically takes ampicillin.But antibiotic is indiscriminate
With that can cause intravaginal flora imbalance, the time of antibiotic usage is longer, and the chance for infecting candida albicans is also more.There are text in foreign countries
Report is offered, using the people of antibiotic than unused person, monilial vaginitis infection rate is high 2 times, when use broad-spectrum antibiotic 10
After~14 days, the chance for suffering from monilial vaginitis improves 3 times.
And there are therapeutic effect unobvious in the Chinese medicine of existing treatment vaginitis, antipruritic effect is poor, and immune for improving
Power and suppress HPV (hpv) and infect no obvious effect, and without the effect prepared preoperative vaginal disinfection
Problem.
The content of the invention
It is an object of the invention to exist for the Western medicine of existing treatment vaginitis, drug resistance, treatment cycle are long and pair is made
With big, Chinese medicine therapeutic effect unobvious, antipruritic effect is poor, and strengthen immunity is not present and suppresses HPV (hpv)
The effect of infection, and the problem of without the effect prepared preoperative vaginal disinfection, and provide and a kind of be used to treat vaginitis
External medicine composition and its application.
In order to achieve the above object, present invention employs following technological means：
A kind of external medicine composition for being used to treat vaginitis of the present invention, by each bulk drug group of following parts by weight
Into：25~35 parts of dandelion, 25~35 parts of Lappula echinata, flea stop 25~35 parts, it is 25~35 parts of kuh-seng, 15~25 parts of the tuber of stemona, pale reddish brown
15~25 parts of fourth, 25~35 parts of frutus cnidii, 5~15 parts of pericarpium zanthoxyli, 10~20 parts of the root of Chinese clematis, 25~35 parts of golden cypress and windproof 5~15
Part.
In the present invention, it is preferred to, described external medicine composition is made up of each bulk drug of following parts by weight：Pu Gong
30 parts of English, 30 parts of Lappula echinata, flea stop 30 parts, 30 parts of kuh-seng, 20 parts of the tuber of stemona, 20 parts of Chinese violet, 30 parts of frutus cnidii, pericarpium zanthoxyli 10g, prestige
15 parts of medicine xiaolingxian, 20 parts of golden cypress and windproof 10 parts.
Wherein：
Frutus cnidii：Warming kidney and enhancing body, eliminating dampness, wind-dispelling, desinsection.For impotence, Gong Leng, morbid leucorrhoea duye, arthritis with fixed pain caused by dampness pain in the back, control outside outer
Vaginal eczema, married woman's pruritus vulvae, trichomonas vaginitis.Frutus cnidii is to drug-resistant S. aureus, Pseudomonas aeruginosa and dermatophyte
There is inhibitory action, Trichomonas vaginalis can be killed, contained xanthotoxol also has stronger anti-inflammatory and analgesic activity.
Dandelion：It is bitter, sweet, tremble with fear, Return liver, stomach, be apt to clearing heat and detoxicating, dispersing swelling and dissipating binds, can be with controlling puckery pain of heat gonorrhea.
Kuh-seng：Kuh-seng is the root of pulse family semishrub plant kuh-seng.Property it is bitter, tremble with fear.Return liver, courage, large intestine, stomach, bladder warp.Heat-clearing
Eliminating dampness, removing toxic substances, desinsection, diuresis.Cure mainly heat-clearing, eliminating dampness, desinsection；Pruitus, scabies leprosy malignant sore, the erosion of vulva is wet to itch, scrofula, scald；
Control trichomonas vaginitis outside.《Compendium of Materia Medica》：Kuh-seng, the bitter cold of golden cypress, all can kidney tonifying, lid take its bitter eliminating dampness, tremble with fear except heat.Heat
Raw wind, humidogene worm, therefore and can controls wind desinsection.Only kidney water is weak and mutually fiery victor with suitable, the cold sperm if fire declines, true strength deficiency, and
Year, the people of height was unavailable.ZHANG Cong-zheng also cloud, all medicines are all malicious, though radix glycyrrhizae, kuh-seng, poison that can not be unexpectedly, then the five tastes are each for long term usage
Return its dirty, the trouble that must have victory gas increasings partially, all medicines are all right, scholar when tactile class and length can, it is as the same as diet.Press again《The Records of the Historian》
Cloud, granary public affairs Chunyu Yi doctor's doctor's Qi disease carious tooth, moxibustion left hand yangming meridian, gargles three liters, come in and go out careful wind, five, six with kuh-seng soup day
More, this also takes it to go the justice of the damp and hot desinsection of general mood.
Flea stops：It is bitter；It is cold；Mild toxicity；Return liver warp；With clearing heat and detoxicating；Swelling and pain relieving；Cool liver is calmed the frightened effect.
Chinese violet：It is bitter, pungent；It is cold；The thoughts of returning home, Liver Channel；With clearing heat and detoxicating；Cool blood detumescence effect.
The root of Chinese clematis：Acrid flavour；It is salty；Slight bitter；It is warm-natured；Mild toxicity；Return bladder；Liver Channel, there is dispelling wind and eliminating dampness；Remove obstruction in channels to relieve pain effect.
Pericarpium zanthoxyli：It is pungent, numb, temperature；Returns spleen, stomach, kidney channel, there are warm in pain, desinsection itching-relieving efficacies；For coldness and pain in the epigastrium, vomit
Tell diarrhea, abdominal pain due to enterositosis；Control eczema, pruritus vulvae outside.
Golden cypress：Heat-clearing and damp-drying drug；Purging intense heat and detonicating.《A supplement to augmented materia medica》：Bark of a cork tree skin, Hand Jueyin is walked, and have the work(of purging intense heat tonifying yin.
With asarum, controlling aphtha has outstanding service.Zhu Zhenheng：Cork tree, walk to the moon, there is the work(of purging intense heat tonifying yin, it is non-it is cloudy in fire, it is unavailable.
Wind-weed nourishing Yin and falling fire, obtain rhizoma atractylodis and remove damp and clearing heat.
The tuber of stemona：For the root tuber of Stemonaceae herbaceos perennial radix stemonae sessilifoliae, Radix stemonae japonicae or radix stemonae tuberosae.Property is sweet, bitter,
Tepor.Return lung passes through.Moisten the lung and relieve the cough, desinsection.
It is windproof：For the windproof root of Umbelliferae herbaceos perennial.Pungent, sweet, the tepor of property.Return bladder, liver, the spleen channel.Deliver
Dissipate wind, expel endogenous wind to relieve convulsion, only convulsion, antidiarrheal.
Lappula echinata：Property toil, put down, it is poisonous；Enter spleen, stomach, Liver Channel；Effect：Desinsection, clearing heat and detoxicating, strengthening the spleen and stomach.
Golden cypress, kuh-seng bitter are cold in nature, can heat-clearing, eliminating dampness, antipruritic.
Further, the invention also provides a kind of method for preparing described Chinese medicine composition, comprise the following steps：
(1) each bulk drug is weighed by described parts by weight；
(2) after each bulk drug for weighing step (1) mixes, add water logging to cross 2~3cm of powder, after soaking 30min, carry out
Once decoct, after decocting 40~90min；Decoction liquor is filtered, collects filtrate；
(3) add water logging to cross 2~3cm of powder into filter residue, carry out secondary decoction, decocting time is 30~80min；Will be secondary
Decoction liquor is filtered, and collects filtrate；
(4) filtrate after the filtrate after first time is decocted decocts with second merges, and produces.
Further, the invention also provides described Chinese medicine composition in the external used medicine for preparing treatment vaginitis
Purposes.
And described Chinese medicine composition is preparing the application in suppressing human papilloma virus infection medicine.
And application of the described Chinese medicine composition in operation consent cleaning intravaginal drug is prepared.
In order to effect a radical cure vaginitis, make medicine rapid-onset, the invention also provides the external application Chinese medicine group described in a kind of cooperation
The oral traditional Chinese medicine composition that compound uses, it is made up of each bulk drug of following parts by weight：50~70 parts of purslane, gingko benevolence 15
~25 parts, 90~120 parts of egg.
Wherein, it is preferred that described oral traditional Chinese medicine composition is made up of each bulk drug of following parts by weight：Purslane 60
Part, 20 parts of gingko benevolence, 110 parts of egg.
A kind of method for preparing described oral traditional Chinese medicine composition, comprises the following steps：
(1) each bulk drug of described parts by weight is weighed respectively；
(2) mixed after purslane is smashed to pieces with gingko benevolence, then add egg and mix well, produce.
Further, the invention also provides described Chinese medicine composition in the endo-medicine for preparing treatment vaginitis
Purposes.
And described Chinese medicine composition is preparing the application in suppressing human papilloma virus infection medicine.
And application of the described Chinese medicine composition in operation consent cleaning intravaginal drug is prepared.
Compared to prior art, the beneficial effects of the present invention are：
1st, the present invention dandelion, Lappula echinata, flea of different properties are stopped, kuh-seng, the tuber of stemona, Chinese violet, frutus cnidii, pericarpium zanthoxyli,
The root of Chinese clematis, golden cypress and windproof all medicine compatibilities, especially frutus cnidii, Lappula echinata, golden cypress, flea are stopped and are combined medication with Chinese violet,
Reaching the good treatment related indication effect of vaginitis, it has the effect of removing damp-heat, antitoxin desinsection, expelling toxin and relieving itching,
There is the effect of certain to treatment bacterial vaginitis, trichomonas vaginitis, colpomycosis.Compared with prior art, originally
Invention Chinese medicine also have it is antipruritic it is rapid, insecticidal and antibacterial is strong, easy to use, cheap, service life is short, quick, curative effect
Significantly, uneasy to recur, cure rate is up to 97%.Every night can relief of symptoms with a medicine, 3-5 medication.And in clinical practice
Do not occur the allergic reaction of skin and mucous membrane, having prompted the stifling decoction of the present invention has good security.
2nd, the present invention is by adding medicine for oral administration, i.e. purslane and medicine for oral administration made from the egg of gingko Renhe, beyond cooperation
Medication, had a significant effect in terms of radical cure vaginitis, rapid-onset.Purslane is to will Hayes in the medicine for oral administration of the present invention
Bacterium, typhoid bacillus, large intestine Erichsen bacterium and staphylococcus aureus, shigella dysenteriae have inhibitory action.Purslane is also containing abundant
Vitamin A sample material, the physiological function of epithelial cell can be promoted, promote the healing of ulcer.Purslane also has contraction to blood vessel
Effect.And gingko benevolence is sweet, mild-natured, there is the effect of convergence and dehumidifying, have special efficacy to abnormal leucorrhea.The two acts synergistically, can
It is antipruritic with clearing heat and promoting diuresis, desinsection, there is good therapeutic action to vaginitis, especially monilial vaginitis.Moreover, this is for oral administration
Medicine does not have side effect, almost dietotherapy, can but play good therapeutic effect.The effect of this medicine for oral administration can be outer with the present invention
Medication reaches good fiting effect.
3rd, Chinese medicine of the invention also suppresses in addition to having good therapeutic effect to vaginitis with strengthen immunity
The effect of HPV (hpv) infects.And the Chinese medicine of the present invention can be also used for carrying out clearly for vagina before surgery
The effect of wash disinfection.
Embodiment
The invention will now be further described with reference to specific embodiments, advantages of the present invention and feature will be with description and
It is apparent.But these embodiments are only exemplary, do not form any restrictions to the scope of the present invention.People in the art
Member to the details and form of technical solution of the present invention it should be understood that can enter without departing from the spirit and scope of the invention
Row modifications or substitutions, but these modifications and replacement are each fallen within protection scope of the present invention.
A kind of preparation for being used to treat the external medicine composition of vaginitis of embodiment 1
(1) each bulk drug is weighed by following weight；
Dandelion 30g, Lappula echinata 30g, flea stop 30g, kuh-seng 30g, tuber of stemona 20g, Chinese violet 20g, frutus cnidii 30g, pericarpium zanthoxyli
10g, root of Chinese clematis 15g, golden cypress 20g and windproof 10g.
(2) after each bulk drug for weighing step (1) mixes, add water logging to cross 2~3cm of powder, after soaking 30min, carry out
Once decoct, after decocting 60min；Decoction liquor is filtered, collects filtrate；
(3) add water logging to cross 2~3cm of powder into filter residue, carry out secondary decoction, decocting time 60min；By secondary decoction
Liquid is filtered, and collects filtrate；
(4) filtrate after the filtrate after first time is decocted decocts with second merges, and it is standby to be divided into two bag decoctions.
A kind of preparation for being used to treat the external medicine composition of vaginitis of embodiment 2
(1) each bulk drug is weighed by following weight；
Dandelion 25g, Lappula echinata 35g, flea stop 35g, kuh-seng 25g, tuber of stemona 23g, Chinese violet 15g, frutus cnidii 30g, pericarpium zanthoxyli
5g, root of Chinese clematis 20g, golden cypress 35g and windproof 10g.
(2) after each bulk drug for weighing step (1) mixes, add water logging to cross 2~3cm of powder, after soaking 30min, carry out
Once decoct, after decocting 90min；Decoction liquor is filtered, collects filtrate；
(3) add water logging to cross 2~3cm of powder into filter residue, carry out secondary decoction, decocting time 30min；By secondary decoction
Liquid is filtered, and collects filtrate；
(4) filtrate after the filtrate after first time is decocted decocts with second merges, and it is standby to be divided into two bag decoctions.
A kind of preparation for being used to treat the external medicine composition of vaginitis of embodiment 3
(1) each bulk drug is weighed by following weight；
35 parts of dandelion, 25 parts of Lappula echinata, flea stop 25 parts, 35 parts of kuh-seng, 25 parts of the tuber of stemona, 15 parts of Chinese violet, frutus cnidii 35
Part, 15 parts of pericarpium zanthoxyli, 20 parts of the root of Chinese clematis, 25 parts of golden cypress and windproof 5 parts.
(2) after each bulk drug for weighing step (1) mixes, add water logging to cross 2~3cm of powder, after soaking 30min, carry out
Once decoct, after decocting 50min；Decoction liquor is filtered, collects filtrate；
(3) add water logging to cross 2~3cm of powder into filter residue, carry out secondary decoction, decocting time 50min；By secondary decoction
Liquid is filtered, and collects filtrate；
(4) filtrate after the filtrate after first time is decocted decocts with second merges, and it is standby to be divided into two bag decoctions.
A kind of preparation for being used to treat the oral traditional Chinese medicine composition of vaginitis of embodiment 4
(1) each bulk drug is weighed by weight as described below respectively：
Purslane 60g, gingko benevolence 20g, egg 110g；
(2) mixed after purslane is smashed to pieces with gingko benevolence, then add egg and mix well, produce.
A kind of preparation for being used to treat the oral traditional Chinese medicine composition of vaginitis of embodiment 5
(1) each bulk drug is weighed by weight as described below respectively：
Purslane 55g, gingko benevolence 25g, egg 100g；
(2) mixed after purslane is smashed to pieces with gingko benevolence, then add egg and mix well, produce.
A kind of preparation for being used to treat the oral traditional Chinese medicine composition of vaginitis of embodiment 6
(1) each bulk drug is weighed by weight as described below respectively：
Purslane 50g, gingko benevolence 15g, egg 90g；
(2) mixed after purslane is smashed to pieces with gingko benevolence, then add egg and mix well, produce.
Application of the Chinese medicine composition of the present invention of embodiment 7 in vaginitis is treated
1st, general information
For the subject of this experiment according to clinical symptoms, gynaecology haves a medical check-up and laboratory examination, is diagnosed as trichomonad or mycotic is cloudy
The scorching patient 700 in road, patient age 22-53 year, average age 36 years old.Symptom shows as leucorrhea increasing, yellow or smelly, cloudy
Portion's itch, vaginal fluid smear for microscopic examination find trichomonad or mould.By all patients stochastic averagina be divided into different treatment groups and
Control group, wherein, each treatment group is 100, and control group is 100.Each group patient symptom, age, the course of disease and hpv infection
Rate is statistically analyzed analysis, and there was no significant difference, has comparativity.
2nd, diagnostic criteria
1), vaginal fluid increases, pruritus vulvue, cusalgia, can be with frequent micturition, odynuria and intercourse pain.2), gynecologial examination：
Can there is vaginal fluid to increase, vagina mucosa it is congested or it is visible be dispersed in bleeding spot, posterior fornix of vagina has volume leukorrhea, in sallow
Color or yellow green purulent secretion, sometimes show bubble or white stiff curdled milk or bean dregs sample.The visible oedema of vulva, scratch,
Pattern erythema.3), vaginal fluid laboratory examination：It can be seen that the gemma and mycelia of trichomonad or candidiasis.
3rd, treatment method
Treatment group one：The Chinese medicine pack that embodiment 1 is prepared, a bag is taken to be put into gassing machine or by medicine liquid heating
Afterwards to carrying out stifling 10min at sufferer；Cleaned again with stifling decoction at sufferer after stifling.Continuous application 4~5 days.
Treatment group two：The Chinese medicine pack that embodiment 1 is prepared, a bag is taken to be put into gassing machine or by medicine liquid heating
Afterwards to carrying out stifling 10min at sufferer；Cleaned again with stifling decoction at sufferer after stifling.Continuous application 4~5 days.Controlled stifling
During treating vaginitis, it need to coordinate and take medicine for oral administration, continuously take 4~5 days；Described medicine for oral administration is prepared by embodiment 4.
Treatment group three：The Chinese medicine pack that embodiment 2 is prepared, a bag is taken to be put into gassing machine or by medicine liquid heating
Afterwards to carrying out stifling 10min at sufferer；Cleaned again with stifling decoction at sufferer after stifling.Continuous application 4~5 days.
Treatment group four：The Chinese medicine pack that embodiment 2 is prepared, a bag is taken to be put into gassing machine or by medicine liquid heating
Afterwards to carrying out stifling 10min at sufferer；Cleaned again with stifling decoction at sufferer after stifling.Continuous application 4~5 days.Controlled stifling
During treating vaginitis, it need to coordinate and take medicine for oral administration, continuously take 4~5 days；Described medicine for oral administration is prepared by embodiment 4.
Treatment group five：The Chinese medicine pack that embodiment 3 is prepared, a bag is taken to be put into gassing machine or by medicine liquid heating
Afterwards to carrying out stifling 10min at sufferer；Cleaned again with stifling decoction at sufferer after stifling.Continuous application 4~5 days.
Treatment group six：The Chinese medicine pack that embodiment 3 is prepared, a bag is taken to be put into gassing machine or by medicine liquid heating
Afterwards to carrying out stifling 10min at sufferer；Cleaned again with stifling decoction at sufferer after stifling.Continuous application 4~5 days.Controlled stifling
During treating vaginitis, it need to coordinate and take medicine for oral administration, continuously take 4~5 days；Described medicine for oral administration is prepared by embodiment 4.
Control group：Conventional metronidazole 2g oral (systemic administration) treatment trichomonas vaginitis is given, for mycotic vagina
Inflammation gives Miconazole bolt 200mg every night, is used in conjunction seven days.
4th, criterion of therapeutical effect
It is effective：Leukorrhea amount and color switch to normally, and itch, vaginal fluid smear for microscopic examination do not send out trichomonad or mould to private parts
Bacterium.
Take a turn for the better：Leukorrhea amount and color switch to normally, and itch, vaginal fluid smear for microscopic examination do not find 1-2 trichomonad to private parts
Or mould.
It is invalid：Clinical symptom and sign is unchanged compared with pre-treatment without improvement.
Other：Other situations of three standards of the above are not met.
5th, treatment results
The treatment group of table 1 and control group result
| Group | Effective (example) | Obvious effective rate | Take a turn for the better (example) | Improvement rate | Invalid (example) | Inefficiency |
| Treatment group one | 87 | 87% | 8 | 8% | 0 | 0 |
| Treatment group two | 95 | 95% | 5 | 5% | 0 | 0 |
| Treatment group three | 83 | 83% | 10 | 10% | 1 | 1% |
| Treatment group four | 92 | 92% | 6 | 6% | 0 | 0 |
| Treatment group five | 84 | 84% | 9 | 9% | 1 | 1% |
| Treatment group six | 93 | 93% | 5 | 5% | 0 | 0 |
| Control group | 59 | 59% | 21 | 21% | 15 | 15% |
It follows that the total effective rate after treatment group's treatment, up to 98% or so, the effective percentage compared with control group 80% has
Obvious advantage.
After 1 year, all healing patients are paid a return visit, wherein, no case was recurrence for the treatment group one to 6 511 of return visit.
In the control group 46 of return visit, 12 are recurred, recurrence rate 26%.
Model case：
Case 1：Ms Zhang, 32 years old, married, certain employee.Vulva and vagina itching, leukorrhea amount is more, medical history more than 2 years.
Existing pruritus vulvae is violent, and yellow such as tears shape is looked in secretion, is smelt as of rotten fish, vaginal fluid smear for microscopic examination finds trichomonad, is diagnosed as trichomonas
Vaginitis.Once medication metronidazole, 2g clothes, recurs again after drug withdrawal.Afterwards with Washout traditional Chinese medicine of the present invention, once a night, while give interior
Medication, a course for the treatment of are cured, no recurrence.
Case 2：Mrs Qu, 33 years old, get married many years, recent pruritus vulvue, leucorrhea increasing, there is peculiar smell, in grumeleuse or
Bean curd slag specimen, night aggravate.Simultaneously also with symptoms such as the urinary tract infections such as frequent micturition, urgent urination, odynuria.Gynecologial examination is found：Vulva
Redness, there is scratch.Vagina mucosa oedema, erythema, there is white chunks thing.After diagnosing, Mrs Liu is to have suffered from colpomycosis,
With external washout with traditional Chinese herbs pharmacy fumigation of the present invention, cleaning, once a night, two courses for the treatment of are cured, no recurrence.
Case 3：Mrs Li, 35 years old, married, certain employee.Pruritus vulvue, flush, vaginal fluid purulence, uterine neck fill
Blood is smooth, and medical history half a year is more.Diagnosis once uses levofloxacin 0.4, Tinidazole Injection with bacterial vaginitis
0.8, once a day, after one week treatment symptom disappears, and is recurred again after January.After go to hospital, with external washout with traditional Chinese herbs medicament of the present invention
Stifling, cleaning, once a night, while gives medicine for oral administration, and two courses for the treatment of are cured, no recurrence.
HPV (hpv) infection is carried out using treatment group and the patient after control group medicine to more than simultaneously to detect
(having determined each group hpv infection rates no significant difference before treatment), after measured, HPV does not occur for the patient for the treatment of group
(hpv) infect, and there are 11 HPV (hpv) infection to be present in control group, thus illustrate, Chinese medicine of the invention has
Suppress HPV (hpv) infection effect well.
Vulva and vagina cleaning are carried out to preoperative patient using the medicine of the present invention, with existing cleaning and sterilizing agent phase
Than there is the effect of equal, the no significant difference between two groups of infection rate after abortion operation.
For those skilled in the art, the technical scheme described in foregoing embodiments can still be repaiied
Change, or equivalent substitution is carried out to which part technical characteristic, within the spirit and principles of the invention, that is made any repaiies
Change, equivalent substitution, improvement etc., should be included in the scope of the protection.
Claims (10)
1. a kind of external medicine composition for being used to treat vaginitis, it is characterised in that by each bulk drug group of following parts by weight
Into：25~35 parts of dandelion, 25~35 parts of Lappula echinata, flea stop 25~35 parts, it is 25~35 parts of kuh-seng, 15~25 parts of the tuber of stemona, pale reddish brown
15~25 parts of fourth, 25~35 parts of frutus cnidii, 5~15 parts of pericarpium zanthoxyli, 10~20 parts of the root of Chinese clematis, 25~35 parts of golden cypress and windproof 5~15
Part.
2. external medicine composition as claimed in claim 1, it is characterised in that be made up of each bulk drug of following parts by weight：
30 parts of dandelion, 30 parts of Lappula echinata, flea stop 30 parts, 30 parts of kuh-seng, 20 parts of the tuber of stemona, 20 parts of Chinese violet, 30 parts of frutus cnidii, pericarpium zanthoxyli
10g, 15 parts of the root of Chinese clematis, 20 parts of golden cypress and windproof 10 parts.
A kind of 3. method for preparing the Chinese medicine composition described in claim 1 or 2, it is characterised in that comprise the following steps：
(1) parts by weight as described in claim 1 or 2 weigh each bulk drug；
(2) after each bulk drug for weighing step (1) mixes, add water logging to cross 2~3cm of powder, after soaking 30min, carry out once
Decoct, after decocting 40~90min；Decoction liquor is filtered, collects filtrate；
(3) add water logging to cross 2~3cm of powder into filter residue, carry out secondary decoction, decocting time is 30~80min；By secondary decoction
Liquid is filtered, and collects filtrate；
(4) filtrate after the filtrate after first time is decocted decocts with second merges, and produces.
4. purposes of the Chinese medicine composition in the external used medicine for preparing treatment vaginitis described in claim 1 or 2.
5. the Chinese medicine composition described in claim 1 or 2 is preparing the application in suppressing human papilloma virus infection medicine.
6. the oral traditional Chinese medicine composition that a kind of external medicine composition coordinated described in claim 1 or 2 uses, its feature exist
In being made up of each bulk drug of following parts by weight：50~70 parts of purslane, 15~25 parts of gingko benevolence, 90~120 parts of egg.
7. oral traditional Chinese medicine composition as claimed in claim 6, it is characterised in that be made up of each bulk drug of following parts by weight：
60 parts of purslane, 20 parts of gingko benevolence, 110 parts of egg.
A kind of 8. method for preparing the oral traditional Chinese medicine composition described in claim 6 or 7, it is characterised in that comprise the following steps：
(1) parts by weight respectively as described in claim 6 or 7 weigh each bulk drug；
(2) mixed after purslane is smashed to pieces with gingko benevolence, then add egg and mix well, produce.
9. purposes of the Chinese medicine composition in the endo-medicine for preparing treatment vaginitis described in claim 6 or 7.
10. the Chinese medicine composition described in claim 6 or 7 is preparing the application in suppressing human papilloma virus infection medicine.
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| CN201710656509.5A CN107349370A (en) | 2017-08-03 | 2017-08-03 | A kind of external medicine composition and its application for being used to treat vaginitis |
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| CN201710656509.5A CN107349370A (en) | 2017-08-03 | 2017-08-03 | A kind of external medicine composition and its application for being used to treat vaginitis |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1179971A (en) * | 1997-09-09 | 1998-04-29 | 张惠媛 | Traditional Chinese medicine for curing leukoplakia vulvae of gynecopathy |
| CN103157051A (en) * | 2013-03-18 | 2013-06-19 | 薛洪喜 | Medicament for treating vaginitis |
-
2017
- 2017-08-03 CN CN201710656509.5A patent/CN107349370A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1179971A (en) * | 1997-09-09 | 1998-04-29 | 张惠媛 | Traditional Chinese medicine for curing leukoplakia vulvae of gynecopathy |
| CN103157051A (en) * | 2013-03-18 | 2013-06-19 | 薛洪喜 | Medicament for treating vaginitis |
Non-Patent Citations (2)
| Title |
|---|
| 许丽绵，主编: "《生殖系统炎症中医疗法》", 30 September 2004, 华南理工大学出版社 * |
| 阳平: "阴道炎", 《健康生活》 * |
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