CN107320658A - A kind of tea-drinking of hypotensive - Google Patents

A kind of tea-drinking of hypotensive Download PDF

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Publication number
CN107320658A
CN107320658A CN201710722769.8A CN201710722769A CN107320658A CN 107320658 A CN107320658 A CN 107320658A CN 201710722769 A CN201710722769 A CN 201710722769A CN 107320658 A CN107320658 A CN 107320658A
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extract solution
tea
drinking
hypotensive
prescription
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不公告发明人
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Foshan Sanshui Charles Agricultural Technology Research Institute (general Partner)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The invention provides a kind of tea-drinking of hypotensive, its percentage composition includes:Prescription extract solution 0.5~3.2%, celery extract solution 3~15%, corn stigma extract solution 3~10%, deionized water surplus;Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:(1~3):(1~3).Using above-mentioned material, it can effectively prevent and reduce hypertension.It can for a long time drink and there is no toxic side effect to human body.Both the trouble of traditional Chinese medicine decoction had been solved, it is beneficial to hyperpietic again to adhere to taking, it is returned to normal level to there is the patient of mild hypertension effectively to adjust blood pressure, to because body cannot take exercise throughout the year or age increase the crowd that is possible to suffer from hypertension can play prevention effect.

Description

A kind of tea-drinking of hypotensive
Technical field
The invention belongs to health tea field, and in particular to a kind of tea-drinking of hypotensive.
Background technology
Hypertension is the most common chronic disease of the mankind, is also the topmost hazards of cardiovascular and cerebrovascular diseases.Due to hypertension Belong to the disease of bulk properties, while the patient with hypertension is also possible to because high blood pressure disease causes the hair of other complication It is raw, injury also result in the heart, brain, kidney and other organs of human body.
From the pathogenesis of hypertension, infringement and caused lesion of the hypertension to internal organs are a very long mistakes Journey.It is a series of complication of hypertension middle and advanced stage, in terms of a large amount of clinical datas, infringement of the hypertension to heart is first when it Punching, it is mainly manifested in following two aspects.Harm one that hypertension is caused to human body, it is to cardiovascular infringement, high blood Pressure is mainly coronary artery to cardiovascular infringement, and the other tiny arteries of heart are then seldom involved.Someone studies Think, because blood pressure increases, coronary artery is upheld, and is stimulated smooth muscle cell proliferation under blood vessel inner layer, is made arterial wall elastic force Albumen, collagen and mucopolysaccharide increase, and intravascular film layer and endothelial cell damage, cholesterol and low-density lipoprotein easily immerse Arterial wall, and fibroplasia;Further, since lysosome increasing in smooth muscle cell, is reduced to cholesterol on arterial wall etc. The elimination of material.Therefore coronary artery is gradually made to occur atherosis, coronary artery stenosis now makes the blood of supply cardiac muscle Reduce, referred to as coronary heart disease, or ischemic heart disease.
Theory of traditional Chinese medical science mainly has two kinds to the etiology and pathogenesis of high blood pressure:
1st, liver person organ of general, consider here, liver is viscus attriguted to wind and wood, and body the moon sun, its property is bold, actively main liter.As sought Consider too or melancholy angry, often liver-yin is secretly consumed, irascibility is partially high, wind sun rises dynamic, liver-yang hyperactivity, pathogen upward attacking orifices in head, and causes dizzy, mesh Dazzle, blood pressure rise.
2nd, the kidney being the origin of congenital constitution, store essential substances life marrow, if inadequate natural endowment, the deficiency of the kidney yin or sexual strain too far, are applied and let out immoderate, make kidney Smart loss, it is impossible to production of sperm marrow, and brain being the marrow sea, marrow sea deficiency, damage of kidney-YIN, water files to nourish wood, liver-yang hyperactivity, and causes dizzy, mesh Dazzle, blood pressure rise.
In at present, the medicament categories of western medical treatment hypertension it is very many, but Western medicine has huge wound to human body organ Evil, and need Long-term taking medicine just to control this disease, it is impossible to reach this sick purpose of radical cure;Traditional Chinese Medical on Treating Hypertension treatment week Phase is especially long, and expensive.
The content of the invention
In order to solve the above problems, the invention provides a kind of tea-drinking of hypotensive.It is from Restoration Mechanism and regulating blood pressure Mechanism is started with, and angiokinesis autogenous control obstacle is gradually eliminated, is made its functional rehabilitation normal.Kidney is protected in liver protection simultaneously, from And the elevated original reason of blood pressure is released, make blood pressure slow and stablize and drop to normally, have no toxic side effect, hence it is evident that improve symptom.
The present invention can be achieved through the following technical solutions.
A kind of tea-drinking of hypotensive, its percentage composition includes:Prescription extract solution 0.5~3.2%, celery extract solution 3~ 15%th, corn stigma extract solution 3~10%, deionized water surplus;
Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:(1~3):(1~3).
Preferably, its percentage by weight of the tea-drinking of hypotensive composition includes:Prescription extract solution 1.8%, celery are extracted Liquid 9%, corn stigma extract solution 6%, deionized water surplus;
Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:2:2.
The preparation method of prescription extract solution of the present invention is:
(1) medicinal material is weighed by the weight ratio of prescription medicinal material, by pulverizing medicinal materials, adds 60~70% ethanol, solid-liquid ratio is 1g: (10~20) ml, is added to 45~60 DEG C of constant temperature, with microwave action 8~30 minutes, filters to obtain alcohol crude extract;
(2) alcohol crude extract is carried out that ethanol is distilled off, concentrated, adsorbed with AB-8 punching polymeric adsorbents, first with distillation Water elution, then with ethanol elution, ethanol eluate is collected, distillation is concentrated into water content 8~20%, obtains prescription to without alcohol taste Extract solution.
The preparation method of celery extract solution of the present invention is:By fresh celery segment, decatize 3~10 minutes, then The celery section that decatize is crossed is ground into juice;60~70% ethanol are added, solid-liquid ratio is 1g:(3~15), it is super using thermostatic type Critical CO2Extraction is extracted to Celery Juice, and control condition is 30~32MPa of extracting pressure, 35~43 DEG C of extraction temperature, CO2 3.5~4.2kg/h of gas flow rate, 5.5~6MPa of separating pressure, extraction time 60~100 minutes, take out extract, through filtering, Vacuum distillation, is concentrated into water content 8~20%, obtains celery extract solution.
The preparation method of corn stigma extract solution of the present invention is:Fresh and tender corn stigma is cut into chunks, length be 0.5~ 1 centimetre, the pure water of 0.1 times of parts by weight is added, it is ground into juice;Add 70% ethanol of 10~15 times of parts by weight, backflow 1~ 3 times, filtrate is collected by filtration, through distillation, concentration, control water content obtains corn stigma extract solution 8~20%.
The preparation method of hypotensive tea-drinking of the present invention is:Prescription extract solution, celery extract solution, corn are weighed by precentagewise Palpus extract solution, it is mixed with deionized water, and ul-trasonic irradiation is mixed, and ultraviolet radiation for sterilizing and disinfecting obtains the tea-drinking of hypotensive.
The related introduction of some compositions of the present invention is as follows:
Folium cortex eucommiae:Taste micro-pungent, it is warm-natured;Enter liver and kidney channel.With functions such as filling liver kidney, strengthening the bones and muscles, kidney deficiency and liver, waist are cured mainly Knees soreness etc..There are the effects such as increase coronary flow, hypotensive, blood glucose increasing, raising immunity function, therefore can be used for treating coronary artery The diseases such as Insufficience of blood flow, hypertension, hypoglycemia;Its water decoction and alcohol extract have obvious sedation and analgesia and antiinflammatory action, use In high blood pressure, the dizziness head pool, uneasy, the insomnia agitation of dysphoria with smothery sensation etc..
Vine tea:Bitter in taste, micro-puckery, it is cool.There is clearing heat and detoxicating, soothing the liver decompression, enhancing people's immunity, it is adaptable to head Dizzy dizzy, tinnitus, insomnia, hypertension etc..Flavones content is up to more than 40% in vine tea, and wherein myricetin can significantly make blood pressure Reduction.
Sanchi flower:Property is sweet cool.There is clearing heat and detoxicating, soothing the liver decompression, enhancing people's immunity, it is adaptable to dizzy mesh Dizzy, tinnitus, insomnia, hypertension etc..Total saposins in sanchi flower in range of doses can reduce the contraction of hyperpietic Press and smaller to Heart rate influences, so as to reach the effect reduced blood pressure.
Chrysanthemum:Sweet-bitter flavor, it is mild-natured;Return lung, kidney two warp.Flavone compound in chrysanthemum not only has good anti-freedom Base and oxidation resistance, and can substantially increase coronary flow, the arrhythmia cordis that confrontation aconitine and chloroform trigger, antagonism calcium from The interior stream of son is so as to improve the convergent force of cardiac muscle cell, with obvious vasodilator, reducing blood lipid, hypotensive activity.
Celery:There is a kind of flavone compound in celery apiolin.Apiolin can significantly reduce Ang II, and (blood vessel is tight Element II) level, reduction systolic pressure and diastolic pressure are opened, reduction heart is washed one's face and rinsed one's mouth and myocardial proliferation coefficient, so as to reach reduction hypertension Patients' blood and the effect with cardioprotection.
The present invention possesses following beneficial effect:
1st, can present invention employs the Common Chinese Herbs that folium cortex eucommiae, vine tea, sanchi flower, chrysanthemum etc. have notable hypotensive Effectively to prevent and reduce hypertension.It can for a long time drink and there is no toxic side effect to human body.Both traditional Chinese medicine is solved The trouble of decoction, is beneficial to hyperpietic and adheres to taking, to there is the patient of mild hypertension effectively to adjust blood pressure again It is set to return to normal level, can play prevention to the crowd for being possible to suffer from hypertension because not liking exercise or age increase makees With.
2nd, the present invention is also with celery as major dose medicine, and one side celery belongs to the material of integration of drinking and medicinal herbs, without any Toxic side effect, and it is more effective to hypotensive;Another aspect celery is easy to get, cheaply, and popularity is big, it is easy to publicize.
3rd, the present invention is also added into the auxiliary medicinal material of this heat-clearing decompression of corn stigma, can both make full use of in corn and lost The waste material abandoned, is conducive to human body hypotensive again, and material is easy to get, cheap, and therefore production cost can also reduce.
Embodiment
To make the technological means of the invention realized, creation characteristic, achieve the goal and be easy to understand with effect, with reference to Embodiment, is expanded on further the present invention.
Embodiment 1
A kind of tea-drinking of hypotensive, its percentage composition includes:Prescription extract solution 1.8%, celery extract solution 9%, corn Must extract solution 6%, deionized water surplus;
Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:2:2.
The preparation method of prescription extract solution described in the present embodiment is:
(1) medicinal material is weighed by the weight ratio of prescription medicinal material, by pulverizing medicinal materials, adds 65% ethanol, solid-liquid ratio is 1g: 15ml, is added to 52.5 DEG C of constant temperature, with microwave action 19 minutes, filters to obtain alcohol crude extract;
(2) alcohol crude extract is carried out that ethanol is distilled off, concentrated, adsorbed with AB-8 punching polymeric adsorbents, first with distillation Water elution, then with ethanol elution, ethanol eluate is collected, distillation is concentrated into water content 14% to without alcohol taste, obtains prescription extraction Liquid.
The preparation method of celery extract solution described in the present embodiment is:By fresh celery segment, decatize 6.5 minutes, then The celery section that decatize is crossed is ground into juice;65% ethanol is added, solid-liquid ratio is 1g:9, using thermostatic type supercritical CO2Extraction Follow the example of and Celery Juice is extracted, control condition is extracting pressure 31MPa, 39 DEG C of extraction temperature, CO2Gas flow rate 3.8kg/h, Separating pressure 5.8MPa, extraction time 80 minutes, take out extract, through filtering, and vacuum distillation is concentrated into water content 14%, Obtain celery extract solution.
The preparation method of corn stigma extract solution described in the present embodiment is:Fresh and tender corn stigma is cut into chunks, length is 0.75 centimetre, the pure water of 0.1 times of parts by weight is added, it is ground into juice;Add 70% ethanol of 12.5 times of parts by weight, backflow 2 It is secondary, filtrate is collected by filtration, through distillation, concentration, control water content obtains corn stigma extract solution 14%.
The preparation method of the present embodiment hypotensive tea-drinking is:Prescription extract solution, celery extract solution, jade are weighed by precentagewise Rice palpus extract solution, it is mixed with deionized water, ul-trasonic irradiation is mixed, ultraviolet radiation for sterilizing and disinfecting obtains the tea-drinking of hypotensive.
Embodiment 2
A kind of tea-drinking of hypotensive, its percentage composition includes:Prescription extract solution 0.5%, celery extract solution 3%, corn Must extract solution 3%, deionized water surplus;
Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:1:1.
The preparation method of prescription extract solution described in the present embodiment is:
(1) medicinal material is weighed by the weight ratio of prescription medicinal material, by pulverizing medicinal materials, adds 65% ethanol, solid-liquid ratio is 1g: 10ml, is added to 52 DEG C of constant temperature, with microwave action 19 minutes, filters to obtain alcohol crude extract;
(2) alcohol crude extract is carried out that ethanol is distilled off, concentrated, adsorbed with AB-8 punching polymeric adsorbents, first with distillation Water elution, then with ethanol elution, ethanol eluate is collected, distillation is concentrated into water content 14% to without alcohol taste, obtains prescription extraction Liquid.
The preparation method of celery extract solution described in the present embodiment is:By fresh celery segment, decatize 3 minutes, then incite somebody to action The celery section that decatize is crossed is ground into juice;65% ethanol is added, solid-liquid ratio is 1g:9mL, using thermostatic type supercritical CO2Extraction Follow the example of and Celery Juice is extracted, control condition is extracting pressure 30MPa, 35 DEG C of extraction temperature, CO2Gas flow rate 3.5kg/h, Separating pressure 5.5MPa, extraction time 60 minutes, take out extract, and through filtering, vacuum distillation is concentrated into water content 8%, obtained Celery extract solution.
The preparation method of corn stigma extract solution described in the present embodiment is:Fresh and tender corn stigma is cut into chunks, length is 0.5 Centimetre, the pure water of 0.1 times of parts by weight is added, it is ground into juice;70% ethanol of 10 times of parts by weight is added, is flowed back 1 time, filtering Filtrate is collected, through distillation, concentration, control water content obtains corn stigma extract solution 8%.
The preparation method of the present embodiment hypotensive tea-drinking is:Prescription extract solution, celery extract solution, jade are weighed by precentagewise Rice palpus extract solution, it is mixed with deionized water, ul-trasonic irradiation is mixed, ultraviolet radiation for sterilizing and disinfecting obtains the tea-drinking of hypotensive.
Embodiment 3
A kind of tea-drinking of hypotensive, its percentage composition includes:Prescription extract solution 3.2%, celery extract solution 15%, corn Must extract solution 10%, deionized water surplus;
Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:3:3.
The preparation method of prescription extract solution described in the present embodiment is:
(1) medicinal material is weighed by the weight ratio of prescription medicinal material, by pulverizing medicinal materials, adds 70% ethanol, solid-liquid ratio is 1g: 20mL, is added to 60 DEG C of constant temperature, with microwave action 30 minutes, filters to obtain alcohol crude extract;
(2) alcohol crude extract is carried out that ethanol is distilled off, concentrated, adsorbed with AB-8 punching polymeric adsorbents, first with distillation Water elution, then with ethanol elution, ethanol eluate is collected, distillation is concentrated into water content 20% to without alcohol taste, obtains prescription extraction Liquid.
The preparation method of celery extract solution described in the present embodiment is:By fresh celery segment, decatize 10 minutes, then incite somebody to action The celery section that decatize is crossed is ground into juice;70% ethanol is added, solid-liquid ratio is 1g:15mL, using thermostatic type supercritical CO2Extraction Follow the example of and Celery Juice is extracted, control condition is extracting pressure 32MPa, 43 DEG C of extraction temperature, CO2Gas flow rate 4.2kg/h, Separating pressure 6MPa, extraction time 100 minutes, take out extract, and through filtering, vacuum distillation is concentrated into water content 20%, obtained Celery extract solution.
The preparation method of corn stigma extract solution described in the present embodiment is:Fresh and tender corn stigma is cut into chunks, length is 1 li Rice, adds the pure water of 0.1 times of parts by weight, ground into juice;70% ethanol of 15 times of parts by weight is added, is flowed back 3 times, filtering is received Collect filtrate, through distillation, concentration, control water content obtains corn stigma extract solution 20%.
The preparation method of the present embodiment hypotensive tea-drinking is:Prescription extract solution, celery extract solution, jade are weighed by precentagewise Rice palpus extract solution, it is mixed with deionized water, ul-trasonic irradiation is mixed, ultraviolet radiation for sterilizing and disinfecting obtains the tea-drinking of hypotensive.
Comparative example 1
Difference with embodiment 1 is that a kind of tea-drinking of hypotensive, its percentage composition includes:Prescription extract solution 0.4%th, celery extract solution 2%, corn stigma extract solution 2%
Comparative example 2
Difference with embodiment 1 is that a kind of tea-drinking of hypotensive, its percentage composition includes:Prescription extract solution 3.3%th, celery extract solution 16%, corn stigma extract solution 11%
Comparative example 3
Difference with embodiment 1 is, without Herba Apii graveolentis extract.
Efficacy validation
The clinical true patient for hypertension is found, is mainly shown as usually:The dizziness head pool, dysphoria with smothery sensation uneasiness, insomnia are irritated Deng.120 people are had, are divided into 6 groups, every group of correspondence drinks 1~3 group of embodiment, the tea-drinking of 1~3 group of comparative example, three times a day, every time 250mL。
View result after 30 days is as a result as follows:
Group The number that illness is improved
Embodiment 1 19
Embodiment 2 16
Embodiment 3 17
Comparative example 1 12
Comparative example 2 12
Comparative example 3 10
Therefore, the present invention effectively can reduce and control hypertension.With reference to the Chinese medicine and hypotensive effect of some alleviation hypertension Fruit is good and has preferable synergy between cheap celery and corn stigma, and composition, can preferably play drop blood The effect of pressure.
Embodiment described above only expresses the several embodiments of the present invention, and it describes more specific and detailed, but simultaneously Therefore the limitation to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that for one of ordinary skill in the art For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention Protect scope.

Claims (6)

1. a kind of tea-drinking of hypotensive, it is characterised in that the tea-drinking of the hypotensive its percentage composition includes:Prescription extract solution 0.5~3.2%, celery extract solution 3~15%, corn stigma extract solution 3~10%, deionized water surplus;
Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:(1~3):(1~3).
2. a kind of tea-drinking of hypotensive according to claim 1, it is characterised in that its weight of the tea-drinking of described hypotensive Percentage composition includes:Prescription extract solution 1.8%, celery extract solution 9%, corn stigma extract solution 6%, deionized water surplus;
Wherein, the weight of prescription is than composition:Folium cortex eucommiae:Vine tea:Sanchi flower=1:2:2.
3. a kind of tea-drinking of hypotensive according to claim 1 or 2, it is characterised in that the system of described prescription extract solution Preparation Method is:
(1) the prescription medicinal material weight ratio as described in claim 1 or 2 weighs medicinal material, by pulverizing medicinal materials, adds 60~70% second Alcohol, solid-liquid ratio is 1g:(10~20) ml, was added to 45~60 DEG C of constant temperature, with microwave action 8~30 minutes, filter alcohol is slightly carried Take liquid;
(2) alcohol crude extract is carried out that ethanol is distilled off, concentrated, adsorbed with AB-8 punching polymeric adsorbents, first with distillation washing It is de-, then with ethanol elution, ethanol eluate is collected, distillation is concentrated into water content 8~20% to without alcohol taste, obtains prescription extraction Liquid.
4. a kind of tea-drinking of hypotensive according to claim 1 or 2, it is characterised in that the system of described celery extract solution Preparation Method is:By fresh celery segment, decatize 3~10 minutes, then the celery section that decatize is crossed is ground into juice;Add 60 ~70% ethanol, solid-liquid ratio is 1g:(3~15), using thermostatic type supercritical CO2Extraction is extracted to Celery Juice, control Condition is 30~32MPa of extracting pressure, 35~43 DEG C of extraction temperature, CO23.5~4.2kg/h of gas flow rate, separating pressure 5.5 ~6MPa, extraction time 60~100 minutes, take out extract, through filtering, and vacuum distillation is concentrated into water content 8~20%, Obtain celery extract solution.
5. the tea-drinking of a kind of hypotensive according to claim 1 or 2, it is characterised in that described corn stigma extract solution Preparation method is:Fresh and tender corn stigma is cut into chunks, length is 0.5~1 centimetre, add the pure water of 0.1 times of parts by weight, grinding Into juice;70% ethanol of 10~15 times of parts by weight is added, flows back 1~3 time, filtrate is collected by filtration, through distillation, is concentrated, control Water content obtains corn stigma extract solution 8~20%.
6. the preparation method of the tea-drinking of a kind of hypotensive as described in any one of Claims 1 to 5, it is characterised in that described Preparation method is:Percentage as described in claim 1 or 2 weighs prescription extract solution, the celery as described in claim 3~5 Extract solution, corn stigma extract solution, it is mixed with deionized water, and ul-trasonic irradiation is mixed, and ultraviolet radiation for sterilizing and disinfecting obtains hypotensive Tea-drinking.
CN201710722769.8A 2017-08-21 2017-08-21 A kind of tea-drinking of hypotensive Withdrawn CN107320658A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107714969A (en) * 2017-10-18 2018-02-23 广州市汇吉科技企业孵化器有限公司 A kind of tea-drinking of hypotensive
CN110432349A (en) * 2019-08-20 2019-11-12 李林奇 It is a kind of can antihypertensive, hyperlipidemia, hyperglycemia tea production method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273697A (en) * 2011-08-16 2011-12-14 华南理工大学 Cane tea composite beverage and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273697A (en) * 2011-08-16 2011-12-14 华南理工大学 Cane tea composite beverage and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107714969A (en) * 2017-10-18 2018-02-23 广州市汇吉科技企业孵化器有限公司 A kind of tea-drinking of hypotensive
CN110432349A (en) * 2019-08-20 2019-11-12 李林奇 It is a kind of can antihypertensive, hyperlipidemia, hyperglycemia tea production method

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Application publication date: 20171107