CN107308410A - A kind of emulsifiable paste for alleviating genital herpes pruritis - Google Patents
A kind of emulsifiable paste for alleviating genital herpes pruritis Download PDFInfo
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- CN107308410A CN107308410A CN201710549370.4A CN201710549370A CN107308410A CN 107308410 A CN107308410 A CN 107308410A CN 201710549370 A CN201710549370 A CN 201710549370A CN 107308410 A CN107308410 A CN 107308410A
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- Prior art keywords
- emulsifiable paste
- affected part
- pruritis
- alleviating
- genital herpes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention discloses a kind of emulsifiable paste for alleviating genital herpes pruritis, it is characterised in that:The emulsifiable paste by five kinds of components of following mass parts uniformly pulverize it is last with mass parts for 200 350 isopropyl myristate it is uniform mix after emulsifiable paste is made, five kinds of components are：Radix Aconiti Kusnezoffii 20 35, radix scutellariae 70 90, curcuma zedoary 15 25, borneol 30 45, the coptis 20 35.The emulsifiable paste has preferable refrigerant anesthetic effect, the scratchiness of private parts can effectively be alleviated by being applied to genitals affected part, prevent patient at night from scratching affected part due to pudendal pruritus, bleb rupture is caused to induce infection, drug therapy can be coordinated simultaneously carries out bactericidal antiphlogistic to skin surface, prevents other courses of infection of affected part external skin.
Description
Technical field
The present invention relates to a kind of emulsifiable paste for alleviating genital herpes pruritis.
Technical background
Genital herpes is by herpes simplex virus（HSV）Caused sexually transmitted disease, mainly HSV-2 types, Shao Shuowei
HSV-1 types.It is one of common venereal disease.Genital herpes can recurrent exerbation, to patient health and psychological impact it is larger；
In VD hospital, clinically male sex organ bleb refers to herpesviral（Herpesviruses）, it is medium small pair of group
Stock DNA virus, there is more than 100 members, according to its physicochemical property point tri- subfamily α herpesvirals of α, β, γ（Such as herpe simplex disease
Poison, the herpes zoster virus of varicella one）Growth rate is fast, causes cytopathy.β herpesvirals（Such as cytomegalovirus）, growth week
Phase is long, infection cell formation giant cell.Gamma herpes viruses, such as Epstein-Barr virus, the target cell of infection is lymphoid cell, can cause pouring
Ba Zengsheng.The host range of herpesvirus infection extensively, can infect the mankind and other vertebrates.Cause mankind's generation has 7
Herpesviral.Herpesviral mainly invades the tissue of ectodermal origin, including skin, mucous membrane and nerve fiber.Infection site and
Caused disease is varied, and has the trend of latent infection, seriously threatens human health.
Genital herpes is to be less susceptible to thoroughly healing, and easy recurrent exerbation, for the treatment of genital herpes, also has at present
Many problems are not solved, and treatment can't thoroughly remove virus, can not prevent disease palindromia.The purpose for the treatment of is mainly
Relief of symptoms, mitigate pain, shorten the course of disease and prevent scabies secondary infection etc..
When genital herpes is fallen ill, itch at sufferer can be caused hard to bear, unconscious can especially go to grab in night patient
Affected part is scratched, causes genital skin damaged, causes infection area to expand.
At present, in the market not yet has a kind of emulsifiable paste for alleviating genital herpes pruritis.
The content of the invention
In view of the above-mentioned problems, the present invention provide it is a kind of alleviate genital herpes pruritis emulsifiable paste, the emulsifiable paste it is beneficial
Part has：
1st, with preferable refrigerant anesthetic effect, the scratchiness of private parts can effectively be alleviated by being applied to genitals affected part, be prevented
Patient at night scratches affected part due to pudendal pruritus, causes bleb rupture to induce infection.
2nd, can coordinate drug therapy carries out bactericidal antiphlogistic to skin surface, prevents other diseases of affected part external skin
Bacterium infects.
The technical proposal of the invention is realized in this way：A kind of emulsifiable paste for alleviating genital herpes pruritis is by following mass parts
Five kinds of components uniformly pulverize it is last with mass parts for 200-350 isopropyl myristate it is uniform mix after breast is made
Cream, five kinds of components are：Radix Aconiti Kusnezoffii 20-35, radix scutellariae 70-90, curcuma zedoary 15-25, borneol 30-45, coptis 20-35.
Embodiment：
A kind of emulsifiable paste for alleviating genital herpes pruritis is uniformly pulverized last by five kinds of components of following mass parts
Emulsifiable paste is made after uniformly being mixed for 200-350 isopropyl myristate with mass parts, five kinds of components are：Radix Aconiti Kusnezoffii 20-35, Huang
A kind of reed mentioned in ancient books 70-90, curcuma zedoary 15-25, borneol 30-45, coptis 20-35.
Several preferred embodiments of given below medicine.
Radix Aconiti Kusnezoffii 20-35, radix scutellariae 70-90, curcuma zedoary 15-25, borneol 30-45, coptis 20-35, the myristic acid of mixing
Isopropyl ester is 200.
Radix Aconiti Kusnezoffii 20-35, radix scutellariae 70-90, curcuma zedoary 15-25, borneol 30-45, coptis 20-35, the myristic acid of mixing
Isopropyl ester is 270.
Radix Aconiti Kusnezoffii 20-35, radix scutellariae 70-90, curcuma zedoary 15-25, borneol 30-45, coptis 20-35, the myristic acid of mixing
Isopropyl ester is 350.
The proportionate relationship of above-mentioned mass parts namely individual component.
Application method：Identical with usual cream application method, cleaning genitals take appropriate emulsifiable paste in illing skin behind affected part
Uniformly smeared, it is easy to use not influence the normal life of patient.
The characteristics of introducing each component individually below and control effect and mechanism.
Radix Aconiti Kusnezoffii：Pungent, hardship, property heat.With narcotic analgesic, spasmolysis stops the effect jerked.Containing aconitine to dermal sensation
Nerve endings produce stimulation, have itch, thermal sensation, then suppress and in local anaesthesia effect.Act on genital skin, can
Prolonged narcotic analgesic, reduces the susceptibility of teleneuron, weakens itch, pain.
Radix scutellariae：Nature and flavor：Hardship, it is cold in nature.Scutellariae,radix is containing flavone compound with baicalein（baicalein）, neobaicalein
（neobaicalein）, i.e. skullcapflavone II（skullcapflavoneⅡ）Based on, there is good antibacterial action：Radix scutellariae decoction
100% concentration, flat band method experiment, to shigella dysenteriae, typhoid bacillus, paratyphosum Bacterium, comma bacillus, Escherichia coli, deformed rod
Bacterium, Pseudomonas aeruginosa, staphylococcus, hemolytic vessel used to hold grain at the imperial sacrifice coccus（A, B）, Diplococcus pneumopniae, corynebacterium diphtheriae etc. have inhibitory action.Radix scutellariae is decocted
Agent test tube method experiment 1：1280 concentration can suppress typhoid bacillus, hemolytic streptococcus a, 1：640 concentration suppress hemolytic hammer
Bacterium B, Diplococcus pneumopniae and shigella flexneri, bacillus tuberculosis typus humanus H37,1：320 concentration can suppress comma bacillus, will Hayes dysentery
Shigella；1：Sonne bacillus has inhibitory action during 80 concentration.Radix scutellariae alcohol immersion liquid 0.5g/ml or 0.05g/ml, uses agar
Inclined-plane culture, decoction and culture medium 1：1 mixing, has inhibitory action to Pseudomonas aeruginosa.Radix scutellariae alcohol immersion liquid 2g/ml concentration, Plating
Experiment has inhibitory action to Escherichia coli, the careless bacillus of tangerine, staphylococcus aureus.Radix scutellariae decoction, alcohol extracting agent 1g/ml concentration, are used
Flat band method has suppression effect to meningococcus when testing.Simultaneously can be interior to trichophyton, Trichophyton concentricum, Lan Shi is yellow perhaps
Tinea bacterium, Microsporon audouini, wool sample microsporum, epidermophyton rubrum, K, W, family name Epidermophyton, star slave card
Salmonella etc. has different degrees of bacteriostasis, can have bacteriostasis to various pathogens.
Curcuma zedoary：Pungent, hardship.With good antibacterial and anti-inflammation functions, emulsifiable paste is applied to after the superficial skin of affected part, drug effect into
Divide in skin surface formation antimicrobial protection layer, prevent the infection of other germs.
Borneol：Pungent, hardship, is slightly cold.There is clearing away heat to and alleviating pain.Can make affected part that there is refrigerant comfort, containing L-Borneol,
A variety of germs are had suppression to stop by the triterpenoid such as the terpene component of carypohyllene etc. half and pier tartaric acid alphitolic acid, dipterocarpol
Itch effect, can effectively prevent infection of other germ reproductions in affected part to affected part.
The coptis:Bitter, it is cold in nature.With antibacterial anesthesia potency.A variety of lifes such as alkali coptisine, worenine are warded off containing small
Alkaloids, tool antibacterial, analgesia drawn game anaesthetic effect, can alleviate the itch sense of discomfort in affected part.
Claims (1)
1. a kind of emulsifiable paste for alleviating genital herpes pruritis, it is characterised in that:The emulsifiable paste is by five kinds of following mass parts
Component uniformly pulverize it is last with mass parts for 200-350 isopropyl myristate it is uniform mix after emulsifiable paste, five is made
Planting component is：Radix Aconiti Kusnezoffii 20-35, radix scutellariae 70-90, curcuma zedoary 15-25, borneol 30-45, coptis 20-35.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710549370.4A CN107308410A (en) | 2017-07-07 | 2017-07-07 | A kind of emulsifiable paste for alleviating genital herpes pruritis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710549370.4A CN107308410A (en) | 2017-07-07 | 2017-07-07 | A kind of emulsifiable paste for alleviating genital herpes pruritis |
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| Publication Number | Publication Date |
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| CN107308410A true CN107308410A (en) | 2017-11-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710549370.4A Withdrawn CN107308410A (en) | 2017-07-07 | 2017-07-07 | A kind of emulsifiable paste for alleviating genital herpes pruritis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108837034A (en) * | 2018-09-29 | 2018-11-20 | 李宝 | A kind of male sex organ bleb cleaning solution |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999374A (en) * | 2016-07-12 | 2016-10-12 | 赵敏 | Sanitary protection pad applicable to pregnant woman and used for treating herpes progenitalis |
-
2017
- 2017-07-07 CN CN201710549370.4A patent/CN107308410A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999374A (en) * | 2016-07-12 | 2016-10-12 | 赵敏 | Sanitary protection pad applicable to pregnant woman and used for treating herpes progenitalis |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108837034A (en) * | 2018-09-29 | 2018-11-20 | 李宝 | A kind of male sex organ bleb cleaning solution |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20171103 |