CN107306992A - A kind of salicylic acid-iodine powder disinfectant and preparation method thereof - Google Patents
A kind of salicylic acid-iodine powder disinfectant and preparation method thereof Download PDFInfo
- Publication number
- CN107306992A CN107306992A CN201710780886.XA CN201710780886A CN107306992A CN 107306992 A CN107306992 A CN 107306992A CN 201710780886 A CN201710780886 A CN 201710780886A CN 107306992 A CN107306992 A CN 107306992A
- Authority
- CN
- China
- Prior art keywords
- salicylic acid
- iodine
- disinfectant
- iodine powder
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/12—Iodine, e.g. iodophors; Compounds thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
Abstract
The present invention relates to a kind of salicylic acid-iodine powder disinfectant, the disinfectant has used salicylic acid and iodine to be compounded, with wide sterilization spectrum, sterilizing ability be strong, work fast, stability are good and environmentally friendly, to humans and animals safety, the characteristics of environmental pollution degree is low, it can be used for livestock and poultry, aquaculture and public place sterilization.Powdery is made in Operand, directly dry spread can be used, it is faster, more convenient；Compared with liquid disinfectant, have the advantages that small volume, packing cost are low, store convenient transportation.Present invention also offers the preparation method of the salicylic acid-iodine powder disinfectant, product preparation process is easy and cost is low.
Description
Technical field
The present invention relates to disinfectant technical field, and in particular to a kind of salicylic acid-iodine powder disinfectant and preparation method thereof.
Background technology
In recent years, because of factors such as environment and drug abuses, the various infectious diseases of livestock and poultry breeding industry are caused to take place frequently, so that livestock and poultry
The relevant industries such as aquaculture, veterinary drug production and operation are by great impact.In addition the taking place frequently of food safety affair, zoonosis
Propagation, the development of large-scale cultivation, and people " prevent overweighting controlling " continually strengthening for medication idea, in the urgent need to being raised for improving
Support environment, prophylactic green safety disinfectant, should to virus effectively be killed, again to livestock and poultry, aquatic products without answer
Swash effect.
Iodine is used for the existing 100 years history of body sterilizing, and iodine is spoken highly of as the efficiency of antiseptic, this master
If because it has the unexistent and inaccessiable bactericidal effect of many bactericide.Its has a broad antifungal spectrum, it is small to tissue toxicity,
It is widely used, its sterilizing scope is related to clinic, health, daily life, livestock and poultry cultivation, aquaculture, public place and drink
With water etc., different classes of, different dosage forms, the iodine sterilizing medicine of different efficacies are just widely used in practice, are such as used for human body
Skin, wound surface, mucomembranous surface, surgical instruments, water, the sanitized of the sterilization of drinking water and tableware, for treating
Various human diseases etc..Iodine is distributed widely in nature, all contains iodine in empty gas and water, soil, rock and animal and plant body.
Polyvinylpyrrolidone, also known as PVP, PVP, are a kind of generally acknowledged nontoxic, the harmless hydrophily high scores in the whole world
Sub- polymer.PVP is in itself without antibacterial action, but due to its affinity interaction to cell membrane, and can be closely complexed with iodine,
Therefore iodine can be immediately directed against to the cell surface of bacterium, auxiliary, synergy can be played a part of in sterilization process.
Publication No. CN 104013573A Chinese patent application is related to a kind of high amount of liquid PVP-I, is under
What the raw material of row percentage by weight was prepared from, iodine 5.2%~12.24%；Polyvinylpyrrolidone 10%~24%；KI
2%~4.8%；Potassiumiodate 0.1%~0.24%；Ethanol 15%~36%；Water surplus.High amount of liquid described in the program is gathered
It is rufous thick liquid to tie up ketone iodine, soluble in water, has no stimulation, it is adaptable to operative site, the sterilization of skin and mucosa, also may be used
Sterilization for breeding water body.
Publication No. CN 102919269A Chinese patent application is related to a kind of povidone iodine disinfectant and its preparation side
Method, the povidone iodine disinfectant includes PVP-I (PVP-I), Potassiumiodate and KI, using citric acid and sodium hydroxide
Adjust and contain KI and Potassiumiodate in pH value of solution, the Betagen Solution, under sour environment, there is IO in solution3 -+
5I-+H+=3I2+3H2O reacts, and on the one hand adds effective iodine concentration in solution, on the one hand promotes active iodine slowly to discharge, carry
The bactericidal action time of high povidone iodine disinfectant.
Also need to make improvements iodine-containing disinfectant in the art, to obtain, wide sterilization spectrum, sterilizing ability are strong, act on
Speed is fast, stability is good, and it is convenient to prepare, and cost is low and environmentally friendly, and to humans and animals safety, environmental pollution degree is low
New disinfectant；In addition, in addition it is also necessary to which the disinfectant exists with powder, in order to store and transport, and application is more clever
It is living.
The content of the invention
It is an object of the invention to provide a kind of salicylic acid-iodine powder disinfectant, it can be used for livestock and poultry, aquaculture and public
Place is sterilized, with wide sterilization spectrum, sterilizing ability be strong, work fast, stability are good and environmentally friendly, to humans and animals peace
Entirely, the characteristics of environmental pollution degree is low.It is a further object to provide a kind of preparation of salicylic acid-iodine powder disinfectant
Method, product preparation process is easy and cost is low.
Salicylic acid, also known as septichen, are a kind of important organic synthesis raw materials.In pesticide producing, for closing
Into organophosphorus insecticide isocarbophos, the intermediate isopropyl salicylate and rat poison Warfarin, coumatetralyl of Isofenphos methyl
Intermediate 4 hydroxy coumarin；In medical industry, salicylic acid is in addition to Cidex-7 is itself served as, also as acetyl salicylic
The intermediate of multi-medicaments such as sour (aspirin)；It is also the important source material of the industry such as dyestuff, spices, rubber.The present invention will
Salicylic acid and PVP-I, which are organically combined, to be utilized, and both is had the effect of Synergistic, is supported in environment disinfected and aquatic products
Had broad application prospects in growing.
Salicylic acid and iodine are carried out combination utilization by macromolecule carrier (polyvinylpyrrolidone), made by the present invention
The effect with Synergistic, had broad application prospects in environment disinfected and aquaculture.
To achieve the above object, one aspect of the present invention provides a kind of salicylic acid-iodine powder disinfectant, the disinfectant
Include the component of following mass percent：
Further, the disinfectant includes the component of following mass percent：
Further, the disinfectant includes the component of following mass percent：
In one embodiment, the disinfectant includes the component of following mass percent：Iodine 0.5%, polyethylene pyrrole
Pyrrolidone 80%, salicylic acid 19%, KI：0.4%th, Potassiumiodate：0.1%.
In another embodiment, the disinfectant includes the component of following mass percent：Iodine 5%, polyethylene pyrrole
Pyrrolidone 80%, salicylic acid 13.5%, KI 1%, Potassiumiodate 0.5%.
Another aspect of the present invention provides a kind of preparation method of salicylic acid-iodine powder disinfectant, and methods described is included such as
Lower step：
(1) polyvinylpyrrolidone is added in solid phase reactor, then adds into solid phase reactor iodine, 40~60 DEG C
Lower mixing more than 4 hours, is down to room temperature,
(2) salicylic acid is added into solid phase reactor, is mixed 0.5-1 hours,
(3) and then sequentially add KI, Potassiumiodate, continue to mix 2-5 hours.
Further, mixing more than 6 hours in step (1).
Further, continue to mix 2-3 hours in step (3).
The inventive method has the following advantages that：
(1) double sterilization with salicylic acid and Operand is acted on, and sterilizing ability is strong, work fast, stability are good, right
Humans and animals safety, can effectively reduce livestock and poultry, the sterilization of aquaculture, algae removal dosage, efficient, safety, resistance to organic contamination, increasing
The strong killing action to the blue-green algae in aquatic products, improves quiet absorption of the iodine to bacterium surface calcium, magnesium ion, so as to promote disinfectant
Kill livestock effect；
(2) excellent storage stability, environmental pollution degree is low, degradable；Its preparation method is simple, and production cost is low, production
Product have extensive use value.
(3) powdery is made in Operand, directly dry spread can used, it is faster, more convenient；Compared with liquid disinfectant,
Have the advantages that small volume, packing cost are low, store convenient transportation.
Embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
The embodiment salicylic acid-iodine powder disinfectant includes the component of following mass percent：Iodine 0.5%, polyvinylpyrrolidine
Ketone 80%, salicylic acid 19%, KI：0.4%th, Potassiumiodate：0.1%.
Preparation method includes：
(1) polyvinylpyrrolidone is added in solid phase reactor, then adds into solid phase reactor iodine, 40~60 DEG C
Lower mixing 6 hours, is down to room temperature,
(2) salicylic acid is added into solid phase reactor, is mixed 1 hour,
(3) and then sequentially add KI, Potassiumiodate, continue to mix 3 hours.
Embodiment 2
The embodiment salicylic acid-iodine powder disinfectant includes the component of following mass percent：Iodine 5%, polyvinylpyrrolidone
80%, salicylic acid 13.5%, KI 1%, Potassiumiodate 0.5%.
Preparation method includes：
(1) polyvinylpyrrolidone is added in solid phase reactor, then adds into solid phase reactor iodine, 40~60 DEG C
Lower mixing 6.5 hours, is down to room temperature,
(2) salicylic acid is added into solid phase reactor, is mixed 0.5 hour,
(3) and then sequentially add KI, Potassiumiodate, continue to mix 2.5 hours.
Embodiment 3
The embodiment salicylic acid-iodine powder disinfectant includes the component of following mass percent：Iodine 3%, polyvinylpyrrolidone
75%, salicylic acid 20%, KI 1%, Potassiumiodate 1%.
Preparation method includes：
(1) polyvinylpyrrolidone is added in solid phase reactor, then adds into solid phase reactor iodine, 40~60 DEG C
Lower mixing 5 hours, is down to room temperature,
(2) salicylic acid is added into solid phase reactor, is mixed 1 hour,
(3) and then sequentially add KI, Potassiumiodate, continue to mix 4 hours.
Embodiment 4
The embodiment salicylic acid-iodine powder disinfectant includes the component of following mass percent：Iodine 8%, polyvinylpyrrolidone
72%, salicylic acid 17%, KI 2%, Potassiumiodate 1%.
Preparation method includes：
(1) polyvinylpyrrolidone is added in solid phase reactor, then adds into solid phase reactor iodine, 40~60 DEG C
Lower mixing 7 hours, is down to room temperature,
(2) salicylic acid is added into solid phase reactor, is mixed 1 hour,
(3) and then sequentially add KI, Potassiumiodate, continue to mix 5 hours.
Embodiment 5
The embodiment salicylic acid-iodine powder disinfectant includes the component of following mass percent：Iodine 13%, polyvinylpyrrolidine
Ketone 72%, salicylic acid 10%, KI 4%, Potassiumiodate 1%.
Preparation method includes：
(1) polyvinylpyrrolidone is added in solid phase reactor, then adds into solid phase reactor iodine, 40~60 DEG C
Lower mixing 5 hours, is down to room temperature,
(2) salicylic acid is added into solid phase reactor, is mixed 1 hour,
(3) and then sequentially add KI, Potassiumiodate, continue to mix 5 hours.
Experimental example
First, high temperature accelerated test
The production technology provided according to the present invention produces salicylic acid-iodine powder disinfectant, its thimble test condition：
40 ± 1 DEG C, humidity 75%, accelerated test is done under PE hermetic bag terms of packings, respectively at 1 month, 2 months, 3 months and 6 months
Test specimen is tested.Detection project：Available iodine content；Examination criteria：Using 0.1mol/L sodium thiosulfate titrating solutions
Direct titration, available iodine content should be within the limits prescribed.Result of the test is shown in Table 1.
The thimble test result of table 1
Discuss：The salicylic acid-iodine powder disinfectant that the method provided by the present invention is prepared, is investigated, effectively through high temperature accelerated test
Content of iodine attenuation rate is respectively less than 10%, shows that salicylic acid-iodine powder disinfectant stability is good, is easy to long term storage.
2nd, salicylic acid-iodine powder sanitizer disinfecting effect of the present invention
1 material and method
1.1 test equipment
1.1.1 salicylic acid-iodine powder disinfectant：Prepare, and be diluted with water into respectively containing effective by the methods described of embodiment 1~5
Iodine 500mg/L solution, it is standby.
1.1.2 test strain：Escherichia coli (8099), staphylococcus aureus (ATCC6538) and Candida albicans
(ATCC 10231) was cultivated to the 3rd~4 generation.
1.2 method
1.2.1 the preparation of bacteria suspension
Take staphylococcus aureus (ATCC6538), Escherichia coli (8099), Candida albicans (ATCC 10231) 24h new
Fresh culture, the bacteria suspension for being configured to experimental concentration with the dilution of the phosphate buffer of peptone containing 10g/L is standby.
1.2.2 nertralizer Selection experiment
Using Escherichia coli as representative.Under the conditions of 20 DEG C, if parallel 6 groups of experiments, by bacteria suspension quantitative disinfecting test program
Carry out.1. thimerosal+bacteria suspension；2. (thimerosal+bacteria suspension)+nertralizer；3. nertralizer+bacteria suspension；4. (thimerosal+neutralization
Agent)+bacteria suspension；5. dilution+bacteria suspension (normal bacterium control)；6. dilution+nertralizer+culture medium is used as negative control.
Result of the test, with the 1st group of not long bacterium or only only a few colony growth；2nd group has colony growth, is compared with the 1st group
It is many, but compared with the 3rd, 4,5 groups be few；3rd, 4,5 groups of bacterium numbers it is similar, error rate≤10%；6th group of asepsis growth, is selected neutralization
Agent and its concentration are suitable.Experiment is repeated 3 times.
1.2.3 bacteria suspension quantitative disinfecting test
Under the conditions of 20 DEG C, organic interfering substance and the mixing of bacteria suspension 1: 1 are standby, are sterilized by every test tube 1ml bacteria suspensions and 4ml
Ratio (positive control is hard water) mixing of agent, effect to the scheduled time is drawn in 0.5ml bacterium medicine addition 4.5ml nertralizers and mixed
It is even.Neutralization 10min, takes liquid 1ml to be inoculated with plate, pours into corresponding agar medium, and 37 DEG C of culture 48h calculate bacterium colony
Number, calculates and kills logarithm value.Experiment is repeated 3 times.
2 results
2.1 nertralizer Selection experiments
Result of the test shows, under the conditions of 20 DEG C, the sodium thiosulfate of+1% Tween 80 of 1% lecithin+0.5% it is sterile
PBS solution, can effectively neutralize the thimerosal residual action of residual, and nertralizer and neutralized reaction product are to experiment bacterial growth and culture
Base has no significant effect.
2.2 bacteria suspension quantitative disinfecting tests
Result of the test shows, under the conditions of 20 DEG C, in available iodine 500mg/L, and salicylic acid-iodine powder disinfectant is to golden yellow
Staphylococcus, Escherichia coli, Candida albicans effect 3min, kill logarithm value >=5.0.It the results are shown in Table 2.
The salicylic acid-iodine powder sanitizer disinfecting effect of table 2
Note：Test temperature is 20 DEG C, Negative control Sterile growth, is as a result 3 experiment average values.
3 discuss
Salicylic acid-iodine powder disinfectant prepared by embodiment 1-5 is pressed in this experimental study, there is good killing effect to microorganism
Really.
Although above with general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (8)
1. a kind of salicylic acid-iodine powder disinfectant, it is characterised in that the disinfectant includes the component of following mass percent：
2. salicylic acid-iodine powder disinfectant as claimed in claim 1, it is characterised in that the disinfectant includes following quality percentage
The component of ratio：
3. salicylic acid-iodine powder disinfectant as claimed in claim 1, it is characterised in that the disinfectant includes following quality percentage
The component of ratio：
4. salicylic acid-iodine powder disinfectant as claimed in claim 1, it is characterised in that the disinfectant includes following quality percentage
The component of ratio：Iodine 0.5%, polyvinylpyrrolidone 80%, salicylic acid 19%, KI：0.4%th, Potassiumiodate：0.1%.
5. salicylic acid-iodine powder disinfectant as claimed in claim 1, it is characterised in that the disinfectant includes following quality percentage
The component of ratio：Iodine 5%, polyvinylpyrrolidone 80%, salicylic acid 13.5%, KI 1%, Potassiumiodate 0.5%.
6. the preparation method of the salicylic acid-iodine powder disinfectant as any one of claim 1-5, it is characterised in that the side
Method comprises the following steps：
(1) polyvinylpyrrolidone is added in solid phase reactor, then adds into solid phase reactor at iodine, 40~60 DEG C and mix
Close more than 4 hours, be down to room temperature,
(2) salicylic acid is added into solid phase reactor, is mixed 0.5-1 hours,
(3) and then sequentially add KI, Potassiumiodate, continue to mix 2-5 hours.
7. the preparation method of salicylic acid-iodine powder disinfectant as claimed in claim 6, it is characterised in that mixing 6 is small in step (1)
When more than.
8. the preparation method of salicylic acid-iodine powder disinfectant as claimed in claim 6, it is characterised in that continue in step (3) mixed
Close 2-3 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710780886.XA CN107306992A (en) | 2017-09-01 | 2017-09-01 | A kind of salicylic acid-iodine powder disinfectant and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710780886.XA CN107306992A (en) | 2017-09-01 | 2017-09-01 | A kind of salicylic acid-iodine powder disinfectant and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107306992A true CN107306992A (en) | 2017-11-03 |
Family
ID=60176712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710780886.XA Pending CN107306992A (en) | 2017-09-01 | 2017-09-01 | A kind of salicylic acid-iodine powder disinfectant and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107306992A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114532357A (en) * | 2022-02-23 | 2022-05-27 | 山西巴盾环境保护技术研究所 | Solid material capable of generating and releasing iodine by reaction in water and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810198A (en) * | 2010-05-06 | 2010-08-25 | 佛山市正典生物技术有限公司 | Salicylic acid-iodine disinfector and preparation method thereof |
| CN103184110A (en) * | 2011-12-30 | 2013-07-03 | 黄佩英 | Disinfecting and antibacterial washing powder |
| CN105557752A (en) * | 2016-03-03 | 2016-05-11 | 佛山市正典生物技术有限公司 | Iodine salicylate foam-type disinfectant and preparation method thereof |
| CN106342886A (en) * | 2016-08-30 | 2017-01-25 | 四川创美克科技有限公司 | Compound type active iodine disinfectant for livestock, preparing method and purpose thereof |
| CN106386853A (en) * | 2016-08-30 | 2017-02-15 | 四川创美克科技有限公司 | Multi-effect active iodine disinfectant as well as preparation method and application thereof |
-
2017
- 2017-09-01 CN CN201710780886.XA patent/CN107306992A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810198A (en) * | 2010-05-06 | 2010-08-25 | 佛山市正典生物技术有限公司 | Salicylic acid-iodine disinfector and preparation method thereof |
| CN103184110A (en) * | 2011-12-30 | 2013-07-03 | 黄佩英 | Disinfecting and antibacterial washing powder |
| CN105557752A (en) * | 2016-03-03 | 2016-05-11 | 佛山市正典生物技术有限公司 | Iodine salicylate foam-type disinfectant and preparation method thereof |
| CN106342886A (en) * | 2016-08-30 | 2017-01-25 | 四川创美克科技有限公司 | Compound type active iodine disinfectant for livestock, preparing method and purpose thereof |
| CN106386853A (en) * | 2016-08-30 | 2017-02-15 | 四川创美克科技有限公司 | Multi-effect active iodine disinfectant as well as preparation method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 罗明生等: "《药剂辅料大全 第2版》", 31 January 2006, 四川科学技术出版社 * |
| 马祥志等: "《有机化学》", 31 July 2017, 中国医药科技出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114532357A (en) * | 2022-02-23 | 2022-05-27 | 山西巴盾环境保护技术研究所 | Solid material capable of generating and releasing iodine by reaction in water and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101810198B (en) | Salicylic acid-iodine disinfector and preparation method thereof | |
| CN102228058B (en) | Citric acid composite disinfectant | |
| CN107836466A (en) | A kind of tea tree ethereal oil natural disinfectant agent for animals and preparation method thereof | |
| CN101700011A (en) | Compound disinfectant for livestock and poultry raising environment | |
| CN101578984A (en) | Algaecide combined by cinnamic aldehyde, eugenol and citric acid | |
| CN101803611B (en) | Citric acid iodine disinfectant and method for preparing same | |
| CN112741087A (en) | Cold chain food disinfectant and preparation method thereof | |
| CN106234388B (en) | A kind of composition pesticide of alkene containing benzo fluorine bacterium azoles and jamaicin | |
| CN104798775B (en) | A kind of cationic surfactant composite disinfectant for animals | |
| CN109954396A (en) | A kind of sterilizing deodorization agent of livestock and poultry cultivation | |
| CN111617063B (en) | Washing-free disinfectant | |
| CN105010401A (en) | Seed treating agent adopting microorganisms | |
| Andrews et al. | Antimicrobial hydrogels formed by crosslinking polyallylamine with aldaric acid derivatives | |
| CN107306992A (en) | A kind of salicylic acid-iodine powder disinfectant and preparation method thereof | |
| CN102106347A (en) | Cinnamaldehyde, eugenol, thymol and tannin compound bactericide | |
| CN111500490A (en) | Microbial type bacteriostatic and odor-removing preparation as well as preparation method and application thereof | |
| CN103329942B (en) | Compound disinfectant, and preparation method and applications thereof | |
| CN107410355A (en) | A kind of effervescent tablet containing iodo-salicylic acid and preparation method thereof | |
| CN104351180B (en) | A kind of micro-capsule suspension for preventing and treating rice green smut | |
| CN106818744A (en) | Disinfectant for abolishing bacterial biofilm | |
| CN102939966B (en) | A kind of compound disinfectant, its preparation method and application | |
| CN107518001A (en) | A kind of new disinfectant of alcohol containing iodo-salicylic acid and preparation method thereof | |
| CN109221223A (en) | A kind of safe and efficient composite disinfectant | |
| CN114946890A (en) | Biological environment-friendly disinfectant product for efficiently killing new coronavirus and preparation method thereof | |
| CN106973902A (en) | It is a kind of to kill cultivated spore preparation containing amino acid derivativges |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171103 |
|
| RJ01 | Rejection of invention patent application after publication |