CN107271348A - A kind of medical artificial pipeline permeance property test system and its application method - Google Patents
A kind of medical artificial pipeline permeance property test system and its application method Download PDFInfo
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- CN107271348A CN107271348A CN201710546211.9A CN201710546211A CN107271348A CN 107271348 A CN107271348 A CN 107271348A CN 201710546211 A CN201710546211 A CN 201710546211A CN 107271348 A CN107271348 A CN 107271348A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
- G01N15/082—Investigating permeability by forcing a fluid through a sample
- G01N15/0826—Investigating permeability by forcing a fluid through a sample and measuring fluid flow rate, i.e. permeation rate or pressure change
Abstract
The invention discloses a kind of medical artificial pipeline permeance property test system, including water tank, water inlet/delivery port, air inlet, air inlet pipe, air pump, aqueduct, section water permeability test port, overall water permeability/water enter pressure test port, pressure gauge, section infiltration water receiver, overall infiltration water receiver, water inlet/delivery port switch, barostat, section water permeability test switch, entirety water permeability/water and enter pressure test switch, filling pipe end, floating lever, hydraulic pressure air pressure balance pipe.During the use of above-mentioned test system, when carrying out the test of section water permeability, water permeability test switch in section is opened, and overall water permeability/water enters pressure test switch closing；When the overall water permeability test of progress and water enter pressure test, overall water permeability/water enters pressure test switch and opened, and water permeability test switch in section is closed.The section water permeability, overall water permeability and water that the device can meet artificial blood vessel and other medical artificial pipelines simultaneously enter the test request of pressure, convenient and swift.
Description
Technical field
The invention belongs to the field of test instrument of bio-medical material, and in particular to a kind of medical artificial pipeline permeance property
Test system and its application method, it is intended to test the medical artificial pipes such as artificial blood vessel, artificial oesophagus, artificial urinary canal and intestinal stent
The tube wall section water permeability in road, overall water permeability and water enter the test device of pressure.
Background technology
With the development of bio-medical material, the various transplanting products for human body are more and more, and it is used as alternative material
Material plays a role in human body, it is necessary to possess certain leakproof, so as to ensure that blood or tissue fluid after transplanting will not be sent out
Raw leakage problems.Therefore, human pipeline must carry out permeance property to it before transplantation and test.For example, blood vessel is
Transport blood, distribution blood and the vitals for carrying out the effects such as nutriment exchange are played in human body, when the blood in human body
When lesion occurs for tubing, treatment just must be replaced or repaired accordingly.According to international standard ISO 7198：2016, people
Hematopoiesis pipe must meet the permeability of clinical requirement, and permeability is excessive, easy oozing of blood；If too small, material and battalion can not be carried out
Support and exchange, blood vessel loses the effect of script, will cause graft failure, so artificial blood vessel carries out permeability after completion is prepared
Test be necessary.The permeability of artificial blood vessel refers to certain liquid to the strong of artificial blood vessel tube wall penetrating power
It is weak, generally characterized with the permeability of water.Mainly there are three characteristic indexs, section permeability, overall water permeability and water enter pressure
Power.Section permeability refers under 120 mmHg static pressures, through the water-carrying capacity in sample unit area in the unit interval, wherein
Water-carrying capacity mainly has two kinds of volume metering and mass metrology, and the unit of volume metering is ml/cm2/min, the unit of weight metering
It is g/cm2/min.Overall water permeability refers under 120 mmHg static pressures, in the unit interval through whole artificial blood tube wall or
The water penetration flow of its representative pipeline section, unit is consistent with the infiltrative unit in section.Water enters including pressure refers to artificial blood vessel
Under the cumulative hydraulic pressure effect in portion, its critical leaks（Outer surface water breakthrough）When water pressure, unit represents by the unit of hydraulic pressure.Separately
Outside, different transplanting products to it is infiltrative requirement there is larger difference, even identical transplanting product be implanted in it is different
Position, is also not quite similar to its infiltrative requirement.So, often weigh it using the water permeability of bio-medical material
In blood and the permeance property of other tissue fluid systems.
At present, in the market can not meet the test needs of artificial blood vessel for the test device of fabric permeability.It is seen in report
The device for being used to test artificial blood vessel water permeability in road, existing defects.As described in China Patent Publication No. CN1460847A
Device be using certain altitude water column gravity meet 120 mmHg static pressure, but this method by gravitational field influenceed compared with
Greatly, and be to ensure certain pressure by circulating water, being not sufficiently stable, and treat the shape and size scope of test sample has
One definite limitation.The device of the overall water permeability of artificial blood vessel as described in China Patent Publication No. CN105021510A, the dress
Put that pressure is controllable, for testing the overall water permeability of artificial blood vessel, but the section that can not be used for testing artificial blood vessel be oozed
Permeability and water enter pressure.Can be to artificial blood vessel, artificial oesophagus, artificial urinary canal and intestinal stent etc. in addition, not currently existing
The section water permeability of medical artificial pipeline, overall water permeability and water, which enter pressure, to be carried out while the test device of test.Therefore,
Section permeability, overall permeability and the water that invention can test medical artificial pipeline simultaneously enter the device of pressure, with important
Meaning.
The content of the invention
It is an object of the invention to provide a kind of medical artificial pipeline permeance property test system, so as to solve the above problems.
The present invention provides a kind of medical artificial pipeline permeance property test system, including：Overall water permeability/water enters pressure
Test port, section water permeability test port, water tank and air pump, the water tank are provided with air inlet, the air inlet and institute
State air pump to connect by air inlet pipe, the air inlet pipe is provided with barostat, the water tank is provided with water inlet/delivery port, institute
State into water/water outlet provided with water inlet/delivery port switch, one end of aqueduct connects the water tank, and the other end is divided into first
Two pipelines of aqueduct branch pipe and the second aqueduct branch pipe, the lower section of the first aqueduct branch pipe connects the overall water penetration
Property/water enters pressure test port, the lower section of the second aqueduct branch pipe connects the section water permeability test port, described
First aqueduct branch pipe enters provided with overall water permeability/water to be additionally provided with pressure test switch, the first aqueduct branch pipe
Pressure gauge, the second aqueduct branch pipe tests switch provided with section water permeability.
Further technical scheme, the overall water permeability/water enters pressure test port and the test of section water permeability
The overall infiltration water receiver and section infiltration water receiver that are respectively arranged below with for receiving liquid body exudate of port.
Further technical scheme, the quantity at least two of the barostat.
Floating lever is provided with further technical scheme, the water tank, the lower wall of the water tank is provided with filling pipe end, described floating
Lever is arranged on the top of filling pipe end, and the filling pipe end is arranged on the top of the water inlet/delivery port.
It is provided with hydraulic pressure air pressure balance pipe in further technical scheme, the water tank, the hydraulic pressure air pressure balance pipe is by institute
State water tank and be separated into the first sub- casing and the second sub- casing, the floating lever and the filling pipe end are arranged on the described second sub- casing
In, the connector of the air inlet and the aqueduct is arranged in the first sub- casing.
Further technical scheme, the section water permeability test port includes top connection and lower contact, it is described on connect
The inwall of head is provided with spacing ring, and sealing ring is arranged on the lower section of the spacing ring, and lower contact is inserted in the top connection, it is described under
Sealing ring described in the top contact of joint.
Further technical scheme, the overall water permeability/water, which enters pressure test port, includes the first testing tube and the
Two testing tubes, first testing tube and the second testing tube are respectively provided with sealing ring outside testing tube inner sealing ring and testing tube,
Side insertion with second testing tube of sealing ring outside the testing tube has the testing tube inner sealing ring
The side of first testing tube.
Further technical scheme, the overall water permeability/water enters pressure test port provided with cone test pipe,
Overall water permeability/the water enters pressure test port and the horizontal plane.
The present invention also provides a kind of application method of medical artificial pipeline permeance property test system, including：
Step one, check that overall water permeability/water enters pressure test port（8）Or section water permeability test port（7）With
And the sealing of device other parts, on the basis of good seal, check whether test water has bubble, beaten if there is bubble
Any test port is opened, bubble is excluded；
Step 2, the water permeability test switch in section（15）Enter pressure test switch with overall water permeability/water（16）Close
Under conditions of open air pump（5）, by adjusting barostat（13）With（14）To change the size of hydraulic pressure, the big I of hydraulic pressure
By pressure gauge（9）Directly read；
Sample, is fixed on overall water permeability/water and enters pressure test port or section water permeability test port by step 3；
Step 4, opens section water permeability switch, waits 10-15 seconds, after stabilization, test starts, and distilled water is by section water
Testing permeability receiver is collected, and each sample is repeatedly tested, averaged, and reduces experimental error.Or open overall
Water permeability/water enters pressure test switch, waits 10-15 seconds, and after stabilization, test starts, and distilled water is connect by integrally permeating water
Receive device to collect, each sample is repeatedly tested, averaged, reduce experimental error.
Step 5, the survey of pressure or section water permeability is entered in the overall water permeability/water for completing medical artificial pipeline
After examination, air pump is closed（5）, feed source is disconnected, water inlet/effluent switch is opened（12）So that unnecessary water by water permeability/
Water enters pressure test port（8）, section water permeability test port（7）And water inlet/delivery port（2）Exclude.
Further technical scheme, the average value described in step 4 can calculate artificial blood vessel water penetration by below equation
Property S：
S= W/（A×t）（1）
W is test data average value in formula, and t is the testing time, and A is test effective area, can be by formula A=π × r × r, its
Middle r is the radius that the effective radius of test sample, i.e. water column flow through sample.When result of calculation is using the volume metering for permeating water,
Unit is ml/cm2/min, and during using the mass metrology for permeating water, unit is g/cm2/min.
A kind of medical artificial pipeline permeance property test system that the present invention is developed, its specific advantage is as follows：
1st, the device can be for test different types medical artificial pipeline, such as artificial oesophagus, artificial enteron aisle, artificial blood vessel and people
Make urethra etc.；
2nd, the device can measure the section water permeability, overall water permeability and water of medical artificial pipeline simultaneously and enter pressure, convenient
Fast；
3rd, change pressure using aeration quantity, more stablize, accurately, conveniently；
4th, vertical direction long range water column is not needed, required pressure just can be reached, the space of device occupancy has been saved；
5th, hardly influenceed by diverse geographic location gravitational field, reduce experimental error；
6th, the invention device is simple in construction, and maintenance costs are low, and does not influence device to test function.
Brief description of the drawings
Fig. 1 is a kind of structural representation of medical artificial pipeline permeance property test system described in the embodiment of the present invention 1
Figure；
Fig. 2 is a kind of section water permeability of medical artificial pipeline permeance property test system described in the embodiment of the present invention 1
The enlarged diagram of test port；
Fig. 3 be the embodiment of the present invention 2 described in a kind of medical artificial pipeline permeance property test system overall water permeability/
Water enters the enlarged diagram of pressure test port；
Fig. 4 be the embodiment of the present invention 3 described in a kind of medical artificial pipeline permeance property test system overall water permeability/
Water enters the enlarged diagram of pressure test port；
Fig. 5 is that a kind of medical artificial pipeline permeance property test system described in the embodiment of the present invention 1 measures artificial blood vessel sample
The test chart of product permeability data.
Wherein：1 it is water tank, 2 be water inlet/delivery port, 3 be air inlet, 4 be air inlet pipe, 5 be air pump, 6 be aqueduct, 7 is
Section water permeability test port, 8 be overall water permeability/water enter pressure test port, 9 be pressure gauge, 10 be section infiltration
Water receiver, 11 be overall infiltration water receiver, 12 be that water inlet/delivery port switch, 13 and 14 are barostat, 15 are section
Water permeability test switch, 16 be overall water permeability/water enter pressure test switch, 17 be filling pipe end, 18 be floating lever, 19 be
Hydraulic pressure air pressure balance pipe, 20 be top connection, 21 be lower contact, 22 be spacing ring, 23 be sealing ring, 24 be the first testing tube, 25
It is sealing ring outside testing tube for testing tube inner sealing ring, 26,27 be the second testing tube, 28 is cone test pipe.
Embodiment
In order to facilitate the understanding of the purposes, features and advantages of the present invention, with reference to the accompanying drawings and examples
Further illustrate technical scheme.But the invention is not restricted to listed embodiment, should also be included in institute of the present invention
It is required that interest field in other any known change.
" one embodiment " or " embodiment " referred to herein refers to may be included at least one implementation of the invention
Special characteristic, structure or characteristic." in one embodiment " that different places occur in this manual not refers both to same
Individual embodiment, nor the single or selective embodiment mutually exclusive with other embodiment.
The invention discloses medical artificial pipeline permeance property test system, including water tank, water inlet/delivery port, air inlet,
Air inlet pipe, air pump, aqueduct, section water permeability test port, overall water permeability/water enter pressure test port, pressure gauge,
Section infiltration water receiver, overall infiltration water receiver, water inlet/delivery port switch, barostat, the test of section water permeability
Switch, overall water permeability/water, which enter the floating lever of pressure test switch, filling pipe end, lower section with sealing device, hydraulic pressure air pressure, puts down
Weighing apparatus hole.Wherein, water inlet/delivery port switch keeps favorable sealing property in whole test process；By the gas for adjusting air inlet
Adjuster is pressed to set the pressure of water, the pressure of water can be read on pressure gauge；When carrying out the test of section water permeability, section
Water permeability test switch is opened, and overall water permeability/water enters pressure test switch closing；Overall water permeability/water is carried out to enter
During pressure test, overall water permeability/water enters pressure test switch opening, and water permeability test switch in section is closed；Lower section band
The floating lever for having sealing device is in order to ensure the dynamic equilibrium of the height of water in water tank, i.e., because floating lever is made by buoyancy
With certain height can be maintained at all the time, and when the liquid level in water tank is too low, water can enter water tank by filling pipe end, when water
During excessive height, the sealing device below floating lever can block filling pipe end, ensure that the constant height of water inside water tank；Water
Pressure air equalizer opening is to ensure that the water in water tank is in connected state all the time, it is to avoid occur causing water due to the effect of air pressure
The highly different problem in face；At the end of test, open water inlet/effluent switch and discharge water, so as to ensure that test device will not pollute.
In other preferred scheme, overall water permeability/water can be improved and enter the structure of pressure test port, improve and cut
The structure of face water permeability test port.
Section water permeability test port can include：Top connection, lower contact, the spacing ring with sealing ring, sealing ring.Its
In, top connection and lower contact detachably, better seal effect are reached by screwing using threaded connection；Fabric sample during test
Product are clamped between the spacing ring with sealing ring and sealing ring, and the position and pressure gauge reach it in same level
Pressure and pressure identical purpose shown in pressure gauge.
Overall water permeability/water, which enters pressure test port, to be included：Testing tube, the testing tube inner sealing of different-diameter
Part, testing tube external sealing part.Inner seal member and external sealing part are combined；Interior sealing part and external seal part
In round table-like, both can freely load and unload, and sealing effectiveness is good when combining.Another scheme, test port is a change
The cone test pipe of diameter.
For the ease of understanding above-mentioned several schemes, now it is divided into three embodiments to describe.
Embodiment 1
Fig. 1 to Fig. 2 is referred to, Fig. 1 is a kind of medical artificial pipeline permeance property test system described in the embodiment of the present invention 1
Structural representation；Fig. 2 is a kind of section of medical artificial pipeline permeance property test system described in the embodiment of the present invention 1
The enlarged diagram of water permeability test port.As shown in figure 1, a kind of human pipeline's water permeability test device in the present apparatus,
Including for storing the water tank 1 of test water, good seal will not deform or burst under larger pressure, Ke Yiyou
The transparent materials such as lucite, engineering plastics and safety glass are made, and shape is cuboid or square, and the length, width and height of casing are all
Control also suitably can be sized size in the range of 20cm-200cm according to the need for difference.For different grafts
Pressure of the road needed for it is different, for the water permeability test of artificial blood vessel, and the water surface elevation h in casing is 1.632m,
（Hydraulic pressure is 120 mmHg in the testing standard of artificial blood vessel, equivalent to 1.632 meter water columns）, section water permeability test port 7,
Overall water permeability/water enters pressure test port 8, pressure gauge 9 and the bottom of water tank 1 and may remain in sustained height, now not
Opening air pump 5 is needed to make it possible to achieve the test to the overall water permeability of artificial blood vessel and section water permeability；Can also
The size of floating lever 18 of the regulation lower section with sealing device changes the height of water in casing, opens air pump 5, realizes to artificial blood
Guan Shui enters the test of pressure.Required according to the difference of different human body pipeline test pressure, sealing device is carried by changing lower section
Floating lever 18 size or open air pump 5, regulation barostat 13 and 14 change hydraulic pressure size, meet test will
Ask.Before test is started, the sealing effectiveness of device is first checked for, method is：Air pump 5 is opened, other switches are remained turned-off
In the state of, appropriate regulation barostat 13 and 14 so that air is full of in device, is confirmed by checking whether gas leakage
Whether the sealing effectiveness of device is good.After confirming that sealing effectiveness is good, air pump 5 is closed, water inlet/effluent switch 12 is opened, steamed
Distilled water enters water tank at water inlet/delivery port 2, and water column is due to the effect of self gravitation, by aqueduct 6 downwards full of whole pipe
Body, checks and confirms each switch in the state of correctly, it is ensured that bubble-free in downcomer, if there is bubble can open section water
Testing permeability switch 15 or overall water permeability/water enter pressure test switch 16 and exclude bubble.After preparation is finished,
Enter in section water permeability test switch 15 and overall water permeability/water under conditions of pressure test switch 16 is closed and open gas
Pump 5, the size of hydraulic pressure is changed by adjusting barostat 13 and 14, why be arranged to 13 and 14 two switch be in order to
Ensure the accuracy of air pressure needed for adjusting, to realize the more accurate of regulation, number of switches can set more than three.Air pump 5
The gas of generation enters at air inlet 3, in the ullage space formation air pressure of water tank, reaches the purpose for changing hydraulic pressure.Lead
The diameter and moderate length of water pipe 6, are made up of transparent materials such as lucite, engineering plastics, and the water in water tank is flowed to from the pipe
Test port, does not have bubble in the pipe is ensured before starting test, reduces the error of experimental result.
As shown in Fig. 2 the device design of test artificial blood tube section water permeability：By sample be cut into and the port 7 under
The same circle of the external diameter of joint 21, is clamped between the spacing ring 22 and sealing ring 23 with sealing ring, screws lower contact 21, really
Good sealing effectiveness is protected, on the premise of the registration of pressure gauge 9 is 163 kPa by adjusting hydrostate 13 and 14, is beaten
Section water permeability switch 15 is driven, is waited 10-15 seconds, after stabilization, test starts, distilled water is connect by the test of section water permeability
Receive device 10 to collect, each sample is repeatedly tested, and is averaged, reduce experimental error.The average value is by below equation
Calculate artificial blood vessel water permeability S：
S= W/（A×t）（1）
W is test data average value in formula, and t is the testing time, and A is test effective area, can be by formula A=π × r × r, its
Middle r is the radius that the effective radius of test sample, i.e. water column flow through sample.When result of calculation is using the volume metering for permeating water,
Unit is ml/cm2/min, and during using the mass metrology for permeating water, unit is g/cm2/min.
Please continue to refer to Fig. 2, section water permeability test port 7 can be made up of stainless steel material, inner hollow, it is ensured that water
Stream passes through, including：Top connection 20, lower contact 21, the spacing ring 22 with sealing ring, sealing ring 23.Wherein, top connection 20 connects with
First 21, using threaded connection, detachably, better seal effect are reached by screwing；Fabric sample is clamped in close during test
Between the spacing ring 22 and 23 of seal, and the position and pressure gauge are in same level, reach and pressure phase shown in pressure gauge
Same purpose.
Table 1
Table 2
Table 1 is that table 2 is that the present embodiment 1 measures infiltration for verifying that the present embodiment 1 tests the artificial blood vessel sample parameters table of effect
Property test extremum difference analysis tables of data.Fig. 5 is a kind of medical artificial pipeline permeance property test described in the embodiment of the present invention 1
System measures the test chart of artificial blood vessel sample permeability data.As can be seen that the present apparatus can be used from two forms and Fig. 5
Section water permeability, overall water permeability and water in on-line testing artificial blood vessel enter pressure.
Embodiment 2
Referring to Fig. 3, Fig. 3 is a kind of the whole of medical artificial pipeline permeance property test system described in the embodiment of the present invention 2
Body water permeability/water enters the enlarged diagram of pressure test port.As shown in figure 3, in the overall water penetration of test artificial blood vessel
Property before, need also exist for carrying out device leak check as described in example 1 above, after confirming that sealing effectiveness is good, lead to
Overregulating barostat 13 and 14 makes the registration of pressure gauge 9 be 163 kPa.Selection is adapted to the testing tube of test sample internal diameter
22, connected by way of the first testing tube 24 is inserted in the side of the second testing tube 27 between testing tube, if after being used for multiple times,
Sealing effectiveness declines, and band can be used to increase sealing effectiveness.After confirming that sealing effectiveness is good, sample one end to be tested is covered
On testing tube, increase its sealing effectiveness with band, it is ensured that water-tight, other end sealing.After being ready to complete, open whole
Body water permeability test switch 16, is waited 10-15 seconds, after stabilization, test starts, and distilled water is by integrally permeating water receiver 11
Collect, each sample is repeatedly tested, averaged, reduce experimental error.The average value is by below equation（1）It can calculate
Go out artificial blood vessel water permeability S.
Please continue to refer to Fig. 3, overall water permeability/water, which enters pressure test port 8, to be included：The testing tube of different-diameter, is surveyed
Test tube interior seal member 25, testing tube external sealing part 26.Interior sealing part 25 and external seal part 26 are in round table-like, and two
Person can freely load and unload, and sealing effectiveness is good.The seal member can be by with certain elastic and conformal performance very strong bubble
Foam plastics are made, it is ensured that can be used for multiple times and not damage and sealing effectiveness will not weaken.During test, one end of human pipeline and its
The test component connection of internal diameter adaptation, other end with the cylinder that its internal diameter is adapted to by sealing.
Embodiment 4
Referring to Fig. 4, Fig. 4 is a kind of the whole of medical artificial pipeline permeance property test system described in the embodiment of the present invention 3
Body water permeability/water enters the enlarged diagram of pressure test port.As shown in figure 4, overall water permeability/water enters pressure test end
Mouth 8 is mainly made up of the cone test pipe 28 of variable diameters, can be made up of the larger plastics of coefficient of friction, if test
During there is the phenomenon of seepage, raw material band can be used to seal.During test, one end of human pipeline and the cone of variable diameters
Test pipe 28 is connected, and other end with the cylinder that its internal diameter is adapted to by sealing.
Embodiment 5
Please continue to refer to Fig. 1 and Fig. 3, as shown in figure 3, the water for carrying out human pipeline enters before the measurement of pressure, and the He of embodiment 1
It is the same described in 2, it is also desirable to carry out leak check to device, but be different from is that need not adjust showing for pressure gauge 9
Number just starts test in 163 kPa, because water enters under pressure refers to artificial blood vessel internally cumulative hydraulic pressure is acted on, and its is critical to ooze
Leakage（Outer surface water breakthrough）When water pressure.Selection is adapted to the testing tube 24 of test sample internal diameter, the second testing tube 27 insertion first
Testing tube 24, if after being used for multiple times, sealing effectiveness declines, can use band to increase sealing effectiveness.Ensure sealing effectiveness
After good, sample to be tested one end is enclosed on testing tube, its sealing effectiveness is increased with band, it is ensured that will not leak, in addition one
End sealing.After being ready to complete, open water and enter pressure test switch 16, wait 10-15 seconds, after stabilization, just can start to survey
Examination.By adjusting barostat 13 and 14, gradually increase pressure, when critical leaks occurs in artificial blood vessel（Outer surface water breakthrough）
When, the reading of pressure gauge 9 is read, i.e. water enters pressure.
It is good in order to ensure the sealing effectiveness of test port, the sealing of some test port can be checked.Such as
When carrying out the test of section water permeability, ready test sample is clamped in test position first, and delivery port is close
Envelope, then opens air pump 5 and section testing permeability switch 15, in the state of other switches are remained turned-off, appropriate regulation
Barostat 13 and 14 so that in device be full of air, confirmed by checking whether gas leakage device sealing effectiveness whether
Well；Similarly, if enter pressure test port 8 using overall water permeability/water and tested, sample can equally be consolidated
It is scheduled on after test port, then carries out leakage check, advantage of this is that sealing effectiveness when further ensuring test, is protected
Card test experiments are smoothed out.Overall water permeability/water as shown in Figure 4 can also be used to enter pressure test port 8 and enter pedestrian
The water of body pipeline enters pressure test, and its method is ibid.
At the end of all tests all, air pump is closed, feed source is disconnected, water inlet/effluent switch 12, section water is opened and oozes
Permeability switch 15, water permeability/water enter pressure test switch 16, discharge unnecessary distilled water, and test terminates.
It should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although with reference to preferable
The present invention is described in detail embodiment, it will be understood by those within the art that, can be to technology of the invention
Scheme is modified or equivalent substitution, and without departing from the spirit and scope of technical solution of the present invention, it all should cover in this hair
Among bright right.
Claims (10)
1. a kind of medical artificial pipeline permeance property test system, it is characterised in that including：Overall water permeability/water enters pressure
Test port（8）, section water permeability test port（7）, water tank（1）And air pump（5）, the water tank（1）It is provided with air inlet
（3）, the air inlet（3）With the air pump（5）Pass through air inlet pipe（4）Connection, the air inlet pipe（4）It is provided with air pressure adjustment
Device, the water tank（1）It is provided with water inlet/delivery port（2）, the water inlet/delivery port（2）Place is provided with water inlet/delivery port switch
（12）, aqueduct（6）One end connect the water tank（1）, the other end is divided into the first aqueduct branch pipe and the second aqueduct branch
Two pipelines of pipe, the lower section of the first aqueduct branch pipe connects the overall water permeability/water and enters pressure test port（8）,
The lower section of the second aqueduct branch pipe connects the section water permeability test port（7）, on the first aqueduct branch pipe
Enter pressure test switch provided with overall water permeability/water（16）, pressure gauge is additionally provided with the first aqueduct branch pipe（9）, institute
State the second aqueduct branch pipe and test switch provided with section water permeability（15）.
2. medical artificial pipeline permeance property test system according to claim 1, it is characterised in that the overall water oozes
Permeability/water enters pressure test port（8）With section water permeability test port（7）Be respectively arranged below with for receiving diffusate
The overall infiltration water receiver of body（11）Water receiver is permeated with section（10）.
3. medical artificial pipeline permeance property test system according to claim 1, it is characterised in that the air pressure adjustment
The quantity at least two of device.
4. medical artificial pipeline permeance property test system according to claim 1, it is characterised in that the water tank（1）
In be provided with floating lever（18）, the water tank（1）Lower wall be provided with filling pipe end（17）, the floating lever（18）It is arranged on filling pipe end
（17）Top, the filling pipe end（17）It is arranged on the water inlet/delivery port（2）Top.
5. medical artificial pipeline permeance property test system according to claim 4, it is characterised in that the water tank（1）
In be provided with hydraulic pressure air pressure balance pipe（19）, the hydraulic pressure air pressure balance pipe（19）By the water tank（1）It is separated into the first sub- casing
With the second sub- casing, the floating lever（18）With the filling pipe end（17）It is arranged in the described second sub- casing, the air inlet
（3）With the aqueduct（6）Connector be arranged in the first sub- casing.
6. medical artificial pipeline permeance property test system according to claim 1, it is characterised in that the section water oozes
Permeability test port（7）Including top connection（20）And lower contact（21）, the top connection（20）Inwall be provided with spacing ring（22）,
Sealing ring（23）It is arranged on the spacing ring（22）Lower section, lower contact（21）Insert the top connection（20）In, it is described under connect
Head（21）Top contact described in sealing ring（23）.
7. medical artificial pipeline permeance property test system according to claim 1, it is characterised in that the overall water oozes
Permeability/water enters pressure test port（8）Including the first testing tube（24）With the second testing tube（27）, first testing tube（24）
With the second testing tube（27）It is respectively provided with testing tube inner sealing ring（25）With sealing ring outside testing tube（26）, with the test
Sealing ring outside pipe（26）Second testing tube（27）Side insertion have the testing tube inner sealing ring（25）'s
First testing tube（24）Side.
8. medical artificial pipeline permeance property test system according to claim 1, it is characterised in that the overall water oozes
Permeability/water enters pressure test port（8）Pipe is tested provided with cone（28）, the overall water permeability/water enters pressure test
Port（8）With the plane-parallel.
9. a kind of application method of medical artificial pipeline permeance property test system, it is characterised in that including：
Step one, check that overall water permeability/water enters pressure test port（8）Or section water permeability test port（7）It is close
Feng Xing, on the basis of good seal, checks whether test water has bubble, if there is bubble opens any one test port,
Exclude bubble；
Step 2, the water permeability test switch in section（15）Enter pressure test switch with overall water permeability/water（16）Close
Under conditions of open air pump（5）, by adjusting barostat（13）With（14）To change the size of hydraulic pressure, the size of hydraulic pressure by
Pressure gauge（9）Directly read；
Sample, is fixed on overall water permeability/water and enters pressure test port by step 3（8）Or section water permeability test port
（7）；
Step 4, opens section water permeability switch（15）, wait 10-15 seconds, after stabilization, test starts, distilled water is by cutting
Face water permeability test receiver（10）Collect, each sample is repeatedly tested, averaged, reduce experimental error；
Or the overall water permeability/water of opening enters pressure test switch（16）, wait 10-15 seconds, after stabilization, test starts,
Distilled water is by integrally permeating water receiver（11）Collect, each sample is repeatedly tested, averaged, reduce experimental error；
Step 5, complete medical artificial pipeline overall water permeability/water enter the test of pressure or section water permeability with
Afterwards, air pump is closed（5）, feed source is disconnected, water inlet/effluent switch is opened（12）So that unnecessary water is entered by water permeability/water
Pressure test port（8）, section water permeability test port（7）And water inlet/delivery port（2）Discharge.
10. the application method of medical artificial pipeline permeance property test system according to claim 9, it is characterised in that
Average value described in step 4 can calculate artificial blood vessel water permeability S by below equation:
S= W/（A×t）（1）
W is test data average value in formula, and t is the testing time, and A is test effective area, can be by formula A=π × r × r, its
Middle r is the radius that the effective radius of test sample, i.e. water column flow through sample.When result of calculation is using the volume metering for permeating water,
Unit is ml/cm2/min, and during using the mass metrology for permeating water, unit is g/cm2/min.
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