CN107260947A - It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof - Google Patents

It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof Download PDF

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Publication number
CN107260947A
CN107260947A CN201710393990.3A CN201710393990A CN107260947A CN 107260947 A CN107260947 A CN 107260947A CN 201710393990 A CN201710393990 A CN 201710393990A CN 107260947 A CN107260947 A CN 107260947A
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medicine composition
hyperlipidemia
chinese
old
sealwort
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夏瑜
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Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
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Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
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Publication of CN107260947A publication Critical patent/CN107260947A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/884—Alismataceae (Water-plantain family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of new medicine composition for treating hyperlipidemia provided according to the understanding mechanism of Chinese traditional treatment hyperlipidemia, each component and its mass parts ratio of the Chinese medicine composition is as follows：50~100g of Radix Rhapontici seu Radix Echinopsis, 100~180g of red yeast rice, 30~120g of hawthorn, 100~260g of the tuber of multiflower knotweed, 100~250g of rhizoma alismatis, 90~160g of sealwort, 30~100g of Fructus Aurantii, 50~160g of the red sage root, the old 60~160g of bacterium, 90~170g of tiger battle, 60~150g of the fruit of Cherokee rose；The medicine that the present invention is provided is a good Chinese prescription.

Description

It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of new medicine composition for treating hyperlipidemia, especially It is the field of the new medicine composition that is used for hyperlipidemia patient and preparation method thereof.
Background technology
Shown according to documents and materials：Hyperlipidemia refers to that blood lipid level is too high, can directly cause some to seriously endanger human body and be good for The disease of health, such as atherosclerosis, coronary heart disease, pancreatitis.
Clinical manifestation：
The clinical manifestation of hyperlipidemia is mainly lipid, and in the xanthoma and lipid caused by intradermal deposition, skin sinks in the blood vessels The caused artery sclerosis of product.Although hyperlipidemia can cause xanthoma, its incidence is simultaneously not bery high；And atherosclerosis Occurrence and development be a kind of slow progressive process again.Therefore, under normal conditions, most of patients and non-evident sympton and different Chang Tizheng.Many people are due to that other reasonses just find there is blood plasma lipoprotein level rise when carrying out blood biochemical inspection.
So, with regard to how to find it is a kind of can effectively treat the Chinese medicine composition of hyperlipidemia, be those skilled in the art urgently To be resolved the problem of.
The content of the invention
With continuing to develop for China's traditional Chinese medicine, in treatment hyperlipidemia, people gradually appreciate middle treatment Treat the advantage of hyperlipidemia, and the advantage such as good effect, instant effect, toxic side effect be small over the course for the treatment of, controlled for existing doctor trained in Western medicine The present situation of hyperlipidemia is treated, the purpose of the present invention is to be to provide a kind of new medicine composition for treating hyperlipidemia, to solve The problem of certainly hyperlipidemia patient is got well early.The medicine is using common Chinese medicine as raw material, by selecting rational medicine Thing and mass parts ratio, can effectively treat above-mentioned hyperlipidemia.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of hyperlipidemia for the treatment of is provided New medicine composition and preparation method thereof, it is characterised in that each component and its mass parts of the Chinese medicine composition are such as Shown in lower：
50~100g of Radix Rhapontici seu Radix Echinopsis, 100~180g of red yeast rice, 30~120g of hawthorn, 100~260g of the tuber of multiflower knotweed, 100~250g of rhizoma alismatis, sealwort 90~160g, 30~100g of Fructus Aurantii, 50~160g of the red sage root, the old 60~160g of bacterium, 90~170g of tiger battle, 60~150g of the fruit of Cherokee rose, Appropriate starch.
It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof, it is characterised in that the Chinese traditional medicine composition Each component and its mass parts of thing are than as follows：
60~90g of Radix Rhapontici seu Radix Echinopsis, 115~160g of red yeast rice, 38~105g of hawthorn, 115~230g of the tuber of multiflower knotweed, 115~220g of rhizoma alismatis, sealwort 100~140g, 38~90g of Fructus Aurantii, 58~140g of the red sage root, the old 70~140g of bacterium, 100~150g of tiger battle, 70~130g of the fruit of Cherokee rose, Appropriate starch.
It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof, it is characterised in that " the optimal side Each component and its mass parts of the Chinese medicine composition of case " are than as follows：
Radix Rhapontici seu Radix Echinopsis 80g, red yeast rice 140g, hawthorn 95g, tuber of multiflower knotweed 200g, rhizoma alismatis 200g, sealwort 120g, Fructus Aurantii 80g, red sage root 120g, bacterium are old 120g, tiger battle 130g, fruit of Cherokee rose 115g, appropriate starch.
It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof, it is characterised in that methods described includes Following steps are prepared from：
A, in addition to starch, by above-mentioned raw materials Chinese medicine pick impurity, dust and dry after, be ground into superfine end according to mass parts ratio and treat With；
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, are put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.9mm~4.0mm）, and then dry, sterilize, dispense close Envelope.
It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof, it is characterised in that the instructions of taking For：By the water pill medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, and dosage 6g/time, it is before meals, simultaneously Eat veterinary antibiotics more.It is within one month a course for the treatment of, 1~4 course for the treatment of of taking medicine, symptom gradually mitigates or fully recovered.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：
Radix Rhapontici seu Radix Echinopsis, nature and flavor：Bitter, cold, the effect of being promoted blood circulation with the clearing heat and detoxicating, carbuncle that disappears, lower breast, relaxing muscles and tendons is swollen and ache, carbuncle for treating acute mastitis Subcutaneous ulcer carbuncle on the back, scrofula sore, alactation, arthritis with fixed pain caused by dampness contraction；
Red yeast rice, nature and flavor：Sweet, temperature, the effect of with helping digestion with stomach, promoting blood circulation and stopping pain, invigorating the spleen, dry stomach, is stagnated, chest for Therapeutic diet The full vexed, indigestion of diaphragm；
Hawthorn, nature and flavor：Sour sweet, tepor, it is nontoxic, with digestion gathered food, change the stagnant stasis of blood the effect of, for Therapeutic diet to be stagnant, gastral cavity abdomen is swollen Bitterly, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain, lochiorrhagia；
The tuber of multiflower knotweed, nature and flavor：Bitter, sweet, puckery, slightly warm in nature, with nourishing the blood and yin, relax bowel, preventing malaria, wind-dispelling, removing toxic substances the effect of, be used for Treat deficiency of blood Light-headedness, palpitaition, insomnia, the soreness and weakness of waist and knees of the deficiency of liver-yin and kidney-yin, poliosis, tinnitus, seminal emission, dry constipation of intestines, long The diseases such as malaria is physically weak, rubella itch, sore carbuncle, scrofula, hemorrhoid；
Rhizoma alismatis, nature and flavor：It is sweet, light, cold in nature, with clearing damp and promoting diuresis, expel the heat-evil treating stranguria the effect of, for treating difficult urination, heat gonorrhea The diseases such as puckery pain, oedema turgor, diarrhea, phlegmatic vertigo, seminal emission；
Sealwort, nature and flavor：It is sweet, flat, it is tired weary for treating weakness of the spleen and the stomach, body the effect of with boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing Power, dry deficiency of food, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, Heat Diabetes；
Fructus Aurantii, nature and flavor：Bitter, pungent, sour, temperature, with regulating the flow of QI to ease the stomach, row stagnant dissipate-swelling the effect of, for treat the chest side of body stagnation of the circulation of vital energy, turgor pain Bitterly, accumulation of food in the stomach and intes tine due to indigestion, stop in phlegm and retained fluid, gastroptosis, prolapse of the anus, sub-official prolapses；
The red sage root, nature and flavor：Bitter, cold nature, the effect of with promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, are used for Treatment menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, lumps in the chest and abdomen, hot numbness swell and ache, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；
Bacterium is old, nature and flavor：It is bitter, pungent, be slightly cold, the effect of with clearing away damp-heat, removing jaundice subcutaneous ulcer, for treating jaundice oliguria, wet sore itch, passing Metachromia icteric hepatitis；
Tiger battle, nature and flavor：Slight bitter, be slightly cold, with expelling wind and removing dampness, scattered stasis pain, it is relieving cough and reducing sputum the effect of, for treating joint numbness Bitterly, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum；
The fruit of Cherokee rose, nature and flavor：It is sour, sweet, puckery, flat, the effect of with astringent sperm contracting urine, relieving diarrhea with astringents, for treating emission and spermatorrhea, the enuresis Under frequent micturition, uterine bleeding band, protracted dysentery and diarrhea.
Medicine of the present invention is the principle based on Chinese traditional treatment hyperlipidemia, from the pathomechanism and pharmacology according to hyperlipidemia Effect is thought：With regard to hyperlipidemia, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had very well to above-mentioned disease Therapeutic effect.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned hyperlipidemia, is prepared using the formula Medicine effect is good, instant effect, is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the present invention's Embodiment is described in further detail：
Embodiment 1：
A kind of new medicine composition for treating hyperlipidemia, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：
Radix Rhapontici seu Radix Echinopsis 80g, red yeast rice 140g, hawthorn 95g, tuber of multiflower knotweed 200g, rhizoma alismatis 200g, sealwort 120g, Fructus Aurantii 80g, red sage root 120g, bacterium are old 120g, tiger battle 130g, fruit of Cherokee rose 115g, appropriate starch.
Embodiment 2：
A kind of new medicine composition for treating hyperlipidemia, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：
Radix Rhapontici seu Radix Echinopsis 90g, red yeast rice 160g, hawthorn 105g, tuber of multiflower knotweed 230g, rhizoma alismatis 220g, sealwort 140g, Fructus Aurantii 90g, red sage root 140g, bacterium Old 140g, tiger battle 150g, fruit of Cherokee rose 130g, appropriate starch.
Embodiment 3：
A kind of new medicine composition for treating hyperlipidemia, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：
Radix Rhapontici seu Radix Echinopsis 100g, red yeast rice 180g, hawthorn 120g, tuber of multiflower knotweed 260g, rhizoma alismatis 250g, sealwort 160g, Fructus Aurantii 100g, red sage root 160g, The old 160g of bacterium, tiger battle 170g, fruit of Cherokee rose 150g, appropriate starch.
Model case
Through clinical conditions hyperlipidemia patient totally 1200, the age is 650 of more than 61 years old, and only 550 are 61 years old Below.850 fully recovered in 1200 patients, effective 248, invalid 102.Total effective rate is up to 91.5%.

Claims (3)

1. a kind of new medicine composition for treating hyperlipidemia, it is characterised in that each component and its quality of the medicine Part is than as follows：
50~100g of Radix Rhapontici seu Radix Echinopsis, 100~180g of red yeast rice, 30~120g of hawthorn, 100~260g of the tuber of multiflower knotweed, 100~250g of rhizoma alismatis, sealwort 90~160g, 30~100g of Fructus Aurantii, 50~160g of the red sage root, the old 60~160g of bacterium, 90~170g of tiger battle, 60~150g of the fruit of Cherokee rose, Appropriate starch.
2. the new medicine composition for the treatment of hyperlipidemia according to claim 1, it is characterised in that the Chinese traditional medicine composition Each component and its mass parts of thing are than as follows：
60~90g of Radix Rhapontici seu Radix Echinopsis, 115~160g of red yeast rice, 38~105g of hawthorn, 115~230g of the tuber of multiflower knotweed, 115~220g of rhizoma alismatis, sealwort 100~140g, 38~90g of Fructus Aurantii, 58~140g of the red sage root, the old 70~140g of bacterium, 100~150g of tiger battle, 70~130g of the fruit of Cherokee rose, Appropriate starch.
3. the new medicine composition of the treatment hyperlipidemia according to claim 1 to 2, it is characterised in that the Chinese medicine Each component and its mass parts of composition are than as follows：
Radix Rhapontici seu Radix Echinopsis 80g, red yeast rice 140g, hawthorn 95g, tuber of multiflower knotweed 200g, rhizoma alismatis 200g, sealwort 120g, Fructus Aurantii 80g, red sage root 120g, bacterium are old 120g, tiger battle 130g, fruit of Cherokee rose 115g, appropriate starch.
CN201710393990.3A 2017-05-28 2017-05-28 It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof Withdrawn CN107260947A (en)

Priority Applications (1)

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Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710393990.3A CN107260947A (en) 2017-05-28 2017-05-28 It is a kind of to treat new medicine composition of hyperlipidemia and preparation method thereof

Publications (1)

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