CN107250349A - 多能干细胞的悬浮培养 - Google Patents

多能干细胞的悬浮培养 Download PDF

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Publication number
CN107250349A
CN107250349A CN201580076646.0A CN201580076646A CN107250349A CN 107250349 A CN107250349 A CN 107250349A CN 201580076646 A CN201580076646 A CN 201580076646A CN 107250349 A CN107250349 A CN 107250349A
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cell
stage
day
culture
culture medium
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B.弗耶
D.拉尼奥斯卡斯
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Janssen Biotech Inc
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Centocor Ortho Biotech Inc
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201580076646.0A 2014-12-19 2015-12-09 多能干细胞的悬浮培养 Pending CN107250349A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462094509P 2014-12-19 2014-12-19
US62/094,509 2014-12-19
PCT/US2015/064713 WO2016100035A1 (en) 2014-12-19 2015-12-09 Suspension culturing of pluripotent stem cells

Publications (1)

Publication Number Publication Date
CN107250349A true CN107250349A (zh) 2017-10-13

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CN201580076646.0A Pending CN107250349A (zh) 2014-12-19 2015-12-09 多能干细胞的悬浮培养

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US (1) US20160215268A1 (https=)
EP (1) EP3234109A4 (https=)
JP (1) JP6800854B2 (https=)
KR (3) KR102519502B1 (https=)
CN (1) CN107250349A (https=)
AR (1) AR103080A1 (https=)
AU (1) AU2015363008B2 (https=)
BR (1) BR112017012974A2 (https=)
CA (1) CA2970935A1 (https=)
MX (1) MX2017008176A (https=)
PH (1) PH12017501153A1 (https=)
RU (1) RU2017125728A (https=)
SG (1) SG11201704961VA (https=)
TW (1) TW201636421A (https=)
WO (1) WO2016100035A1 (https=)
ZA (1) ZA201704868B (https=)

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CN112867787A (zh) * 2018-09-19 2021-05-28 武田药品工业株式会社 胰岛素产生细胞
CN119432595A (zh) * 2023-08-07 2025-02-14 浙江霍德生物工程有限公司 利用生物反应器进行诱导多能干细胞的悬浮培养

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CN111246864A (zh) * 2017-07-21 2020-06-05 森玛治疗公司 干细胞衍生的胰腺β细胞的重聚
KR102738995B1 (ko) * 2017-09-11 2024-12-06 노보 노르디스크 에이/에스 시험관 내 줄기 세포로부터 유래된 nkx6.1 및 c-펩티드 공발현 세포의 농축
EP3710021A4 (en) * 2017-11-15 2021-08-11 Semma Therapeutics, Inc. ISLAND CELL MANUFACTURING COMPOSITIONS AND METHOD OF USE
WO2020033879A1 (en) 2018-08-10 2020-02-13 Semma Therapeutics, Inc. Stem cell derived islet differentiation
US12378572B2 (en) 2018-09-07 2025-08-05 Crispr Therapeutics Ag Universal donor cells
US20220177849A1 (en) * 2019-04-08 2022-06-09 Novo Nordisk A/S Generation of pancreatic endoderm from stem cell derived definitive endoderm
EP3976236A1 (en) 2019-05-31 2022-04-06 W.L. Gore & Associates Inc. A biocompatible membrane composite
CA3139292C (en) 2019-05-31 2025-06-10 Viacyte, Inc. CELL ENCAPSULATION DEVICES WITH REGULATED OXYGEN DIFFUSION DISTANCES
CN114173837A (zh) 2019-05-31 2022-03-11 W.L.戈尔及同仁股份有限公司 生物相容性膜复合材料
EP3975926A1 (en) 2019-05-31 2022-04-06 W.L. Gore & Associates, Inc. A biocompatible membrane composite
CA3150235A1 (en) 2019-09-05 2021-03-11 Alireza Rezania Universal donor cells
PH12022550542A1 (en) 2019-09-05 2023-03-20 Crispr Therapeutics Ag Universal donor cells
WO2022144855A1 (en) 2020-12-31 2022-07-07 Crispr Therapeutics Ag Universal donor cells
WO2025117331A1 (en) * 2023-12-01 2025-06-05 Eli Lilly And Company Methods of making stem cell-derived islet-like cells, as well as populations and compositions including the same

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112867787A (zh) * 2018-09-19 2021-05-28 武田药品工业株式会社 胰岛素产生细胞
CN119432595A (zh) * 2023-08-07 2025-02-14 浙江霍德生物工程有限公司 利用生物反应器进行诱导多能干细胞的悬浮培养

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SG11201704961VA (en) 2017-07-28
KR20230050478A (ko) 2023-04-14
KR20170087520A (ko) 2017-07-28
KR102519502B1 (ko) 2023-04-06
AR103080A1 (es) 2017-04-12
KR20210094141A (ko) 2021-07-28
RU2017125728A3 (https=) 2019-06-03
WO2016100035A1 (en) 2016-06-23
AU2015363008B2 (en) 2021-12-09
EP3234109A4 (en) 2018-06-27
EP3234109A1 (en) 2017-10-25
TW201636421A (zh) 2016-10-16
RU2017125728A (ru) 2019-01-22
KR102281752B1 (ko) 2021-07-23
US20160215268A1 (en) 2016-07-28
AU2015363008A1 (en) 2017-06-29
BR112017012974A2 (pt) 2018-01-09
JP6800854B2 (ja) 2020-12-16
MX2017008176A (es) 2018-02-09
PH12017501153A1 (en) 2017-11-27
KR102700499B1 (ko) 2024-08-28
ZA201704868B (en) 2019-02-27
JP2017537649A (ja) 2017-12-21
CA2970935A1 (en) 2016-06-23

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