CN107184924A - 治疗阴虚感冒的口服液的制备方法 - Google Patents

治疗阴虚感冒的口服液的制备方法 Download PDF

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CN107184924A
CN107184924A CN201710246017.9A CN201710246017A CN107184924A CN 107184924 A CN107184924 A CN 107184924A CN 201710246017 A CN201710246017 A CN 201710246017A CN 107184924 A CN107184924 A CN 107184924A
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陆群英
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Abstract

本发明公开了一种治疗阴虚感冒的口服液的制备方法，由以下重量份的原料浸提得到：女贞子8‑12、北沙参8‑12、麦冬8‑12、玉竹8‑12、黄精8‑12、枸杞子15‑20、熟地8‑12、白芍8‑12、茯苓皮8‑12、马鞭草8‑12、玉米须15‑20、泽泻8‑12、青蒿8‑12、胡黄莲8‑12、十大功劳叶8‑12、白薇8‑12、紫苏15‑20、防风8‑12、荆芥8‑10、生姜8‑12、葱白15‑20、菊花15‑20、倒扣草8‑12以及伤寒草8‑12。

Description

治疗阴虚感冒的口服液的制备方法
技术领域
本发明涉及中医药领域，尤其涉及一种治疗阴虚感冒的口服液的制备方法。
背景技术
阴虚感冒中医病症名，症状为身热，微恶风寒，无汗或微汗，头痛头晕，心烦口渴，手足心热，干咳少痰，舌红，脉细数。传统中医任务，阴虚感冒的病因是：阴虚之体，肺素有燥热。复感外邪，营卫失和，邪正相争，故见身热、微恶风寒；阴虚津少，不能作汗，故无汗或微汗；肺阴不足，清肃之气不行，故干咳少痰；阴虚生内热，其病在阴分，故手足心热；虚火上扰于心，故心烦；阴不敛阳，虚阳上亢，故头痛头晕；口渴、舌红、脉细数为阴虚有热之象。现有方法一般采用滋阴解表的方法治疗阴虚性感冒，但是往往疗程长，治疗效果不尽理想。
发明内容
本发明的一个目的是解决至少上述问题和/或缺陷，并提供至少后面将说明的优点。
本发明的另一个目的是提供一种治疗阴虚感冒的口服液的制备方法，能够得到有效治疗阴虚感冒的的口服液，有效治疗阴虚感冒症，尤其是秋冬季发作的阴虚感冒，治愈效果好。
为实现上述目的和一些其他的目的，本发明采用如下技术方案：
一种治疗阴虚感冒的口服液的制备方法，其中，所述口服液主要通过以下步骤制备得到：
步骤1、将中药组合物干燥粉碎，得到药粉，所述中药组合物包括以下重量份的原料：女贞子8-12、北沙参8-12、麦冬8-12、玉竹8-12、黄精8-12、枸杞子15-20、熟地8-12、白芍8-12、茯苓皮8-12、马鞭草8-12、玉米须15-20、泽泻8-12、青蒿8-12、胡黄莲8-12、十大功劳叶8-12、白薇8-12、紫苏15-20、防风8-12、荆芥8-10、生姜8-12、葱白15-20、菊花15-20、倒扣草8-12以及伤寒草8-12。
步骤2、将药粉与10-30倍体积的质量浓度为60-70％的乙醇溶液混合浸提，浸提结束后加热使乙醇蒸发，得到膏状浸提物。
步骤3、将浸提物加水稀释8-12倍，即得所述治疗阴虚感冒的口服液。
优选的是，所述的治疗阴虚感冒的口服液的制备方法中，步骤2中所述浸提的时间为6-15天，浸提温度为30-40摄氏度。
优选的是，所述的治疗阴虚感冒的口服液的制备方法中，步骤2中，采用旋蒸法使乙醇蒸发，旋蒸温度为50-55摄氏度。
优选的是，所述的治疗阴虚感冒的口服液的制备方法中，步骤2中在浸提过程中每隔6-12小时进行超声震荡20-30分钟。
优选的是，所述的治疗阴虚感冒的口服液的制备方法中，所述中药组合物包括以下重量份的原料：女贞子10、北沙参10、麦冬10、玉竹10、黄精10、枸杞子18、熟地10、白芍10、茯苓皮10、马鞭草10、玉米须18、泽泻10、青蒿10、胡黄莲10、十大功劳叶10、白薇10、紫苏18、防风10、荆芥9、生姜10、葱白18、菊花18、倒扣草10以及伤寒草10。
本发明至少包括以下有益效果：首先，本发明利用中医五行及辨证理论，认为阴虚感冒的病因为：多因阴虚体质，阴亏津少，津液不能作汗，外受风邪，表卫失和出现干咳少痰，头昏头痛，身热，微恶风寒，少汗，面赤，心烦，口干舌燥等感冒症状。
本发明认为，治疗阴虚感冒，宜扶正祛邪，滋阴补肾，同时辅以健脾之药，渗湿助水运化，以新水换旧水之法，所谓“行水则之”，清虚热与邪热，散风邪，从而从根本上治疗阴虚性感冒。
本发明的具体药理为：北沙参：养阴清肺，益胃生津。麦冬：养阴润肺，益胃生津，清心除烦。玉竹：养阴润燥，生津止渴。黄精：补脾益气，润肺，有益脾胃。枸杞子：滋阴补血益肝肾，明目填精。熟地：补血滋阴，益精填髓。白芍：养血和血，平肝，敛阴止汗。茯苓皮：利水渗湿，健脾补中。马鞭草：清利湿热，利水，清热解毒，活血祛痰。玉米须：利尿通淋，利湿渗湿。泽泻：利水渗湿，导中焦湿气，泄热。青蒿：清退虚热，祛风解毒。胡黄莲：清虚热热，凉血，燥湿。十大功劳叶：清热补虚。白薇：清退虚热，清热凉血，利尿通淋。紫苏：解表散寒，行气和胃。防风：祛风解表，配合黄芪之功有发汗解表，补虚益气之功。荆芥：祛风解表，清头目，利咽喉，通鼻窍。生姜：发汗解表，温肺止咳。葱白：发汗解表，通阳利窍，温中行气。菊花：疏散风热，平抑肝阳，清肝，清热解毒。倒扣草：清热解表，利尿，清热解毒。伤寒草：疏散风热，清热除湿，凉血解毒，镇静安神。
本发明通过以下中药合理配伍，补血、清肺而滋阴、养阴，祛风、解表、散寒，辅以清热利湿、益胃生津等，从而从根本上治疗阴虚性感冒，见效快，治愈率高。每日服用所述口服液2-4次，每次服用10-20毫升，5-10日为一个疗程，治愈率达92％。
本发明的其它优点、目标和特征将部分通过下面的说明体现，部分还将通过对本发明的研究和实践而为本领域的技术人员所理解。
具体实施方式
下面对本发明做详细说明，以令本领域普通技术人员参阅本说明书后能够据以实施。
一种治疗阴虚感冒的口服液的制备方法，其中，所述口服液主要通过以下步骤制备得到：
步骤1、将中药组合物干燥粉碎，得到药粉，所述中药组合物包括以下重量份的原料：女贞子8-12、北沙参8-12、麦冬8-12、玉竹8-12、黄精8-12、枸杞子15-20、熟地8-12、白芍8-12、茯苓皮8-12、马鞭草8-12、玉米须15-20、泽泻8-12、青蒿8-12、胡黄莲8-12、十大功劳叶8-12、白薇8-12、紫苏15-20、防风8-12、荆芥8-10、生姜8-12、葱白15-20、菊花15-20、倒扣草8-12以及伤寒草8-12。
步骤2、将药粉与10-30倍体积的质量浓度为60-70％的乙醇溶液混合浸提，浸提结束后加热使乙醇蒸发，得到膏状浸提物。
步骤3、将浸提物加水稀释8-12倍，即得所述治疗阴虚感冒的口服液。
本方案中：
北沙参：养阴清肺，益胃生津。
麦冬：养阴润肺，益胃生津，清心除烦。
玉竹：养阴润燥，生津止渴。
黄精：补脾益气，润肺，有益脾胃。
枸杞子：滋阴补血益肝肾，明目填精。
熟地：补血滋阴，益精填髓。
白芍：养血和血，平肝，敛阴止汗。
茯苓皮：利水渗湿，健脾补中。
马鞭草：清利湿热，利水，清热解毒，活血祛痰。
玉米须：利尿通淋，利湿渗湿。
泽泻：利水渗湿，导中焦湿气，泄热。
青蒿：清退虚热，祛风解毒。
胡黄莲：清虚热热，凉血，燥湿。
十大功劳叶：清热补虚。
白薇：清退虚热，清热凉血，利尿通淋。
紫苏：解表散寒，行气和胃。
防风：祛风解表，配合黄芪之功有发汗解表，补虚益气之功。
荆芥：祛风解表，清头目，利咽喉，通鼻窍。
生姜：发汗解表，温肺止咳。
葱白：发汗解表，通阳利窍，温中行气。
菊花：疏散风热，平抑肝阳，清肝，清热解毒。
倒扣草：清热解表，利尿，清热解毒。
伤寒草：疏散风热，清热除湿，凉血解毒，镇静安神。
所述的治疗阴虚感冒的口服液的制备方法中，步骤2中所述浸提的时间为6-15天，浸提温度为30-40摄氏度。
所述的治疗阴虚感冒的口服液的制备方法中，步骤2中，采用旋蒸法使乙醇蒸发，旋蒸温度为50-55摄氏度。
所述的治疗阴虚感冒的口服液的制备方法中，步骤2中在浸提过程中每隔6-12小时进行超声震荡20-30分钟。
实施例1
一种治疗阴虚感冒的口服液的制备方法，包括以下步骤：
步骤1、将中药组合物干燥粉碎，得到药粉，所述中药组合物包括以下重量份的原料：女贞子10、北沙参10、麦冬10、玉竹10、黄精10、枸杞子18、熟地10、白芍10、茯苓皮10、马鞭草10、玉米须18、泽泻10、青蒿10、胡黄莲10、十大功劳叶10、白薇10、紫苏18、防风10、荆芥9、生姜10、葱白18、菊花18、倒扣草10以及伤寒草10。
步骤2、将药粉与25倍体积的质量浓度为65％的乙醇溶液混合浸提，浸提结束后加热使乙醇蒸发，得到膏状浸提物。
步骤3、将浸提物加水稀释10倍，即得所述治疗阴虚感冒的口服液。
为进一步证明本发明的药物的临床疗效，选择100位患者进行临床观察。100例患者中，年龄最小者25岁，年龄最大者72岁，5-10天为一个疗程，至少服用1个疗程以上。
1、疗效评价标准：
治愈：阴虚感冒症状消失。
显效：阴虚感冒症状明显减轻。
有效：阴虚感冒症状较治疗前减轻。
无效：病情无任何改善的表现。
2、治疗方案：
每次服用10-20毫升所述口服液，每日服用2-4次，每5-10日为一疗程，至少服用1个疗程。
治疗效果统计：
100例患者中，服用5-10天后，治愈92例，显效3例，有效3例，无效2例，治愈率92％，总有效率98％。
尽管本发明的实施方案已公开如上，但其并不仅仅限于说明书和实施方式中所列运用，它完全可以被适用于各种适合本发明的领域，对于熟悉本领域的人员而言，可容易地实现另外的修改，因此在不背离权利要求及等同范围所限定的一般概念下，本发明并不限于特定的细节。

Claims (5)

1.一种治疗阴虚感冒的口服液的制备方法，其中，所述口服液主要通过以下步骤制备得到：
步骤1、将中药组合物干燥粉碎，得到药粉，所述中药组合物包括以下重量份的原料：女贞子8-12、北沙参8-12、麦冬8-12、玉竹8-12、黄精8-12、枸杞子15-20、熟地8-12、白芍8-12、茯苓皮8-12、马鞭草8-12、玉米须15-20、泽泻8-12、青蒿8-12、胡黄莲8-12、十大功劳叶8-12、白薇8-12、紫苏15-20、防风8-12、荆芥8-10、生姜8-12、葱白15-20、菊花15-20、倒扣草8-12以及伤寒草8-12；
步骤2、将药粉与10-30倍体积的质量浓度为60-70％的乙醇溶液混合浸提，浸提结束后加热使乙醇蒸发，得到膏状浸提物；
步骤3、将浸提物加水稀释8-12倍，即得所述治疗阴虚感冒的口服液。
2.如权利要求1所述的治疗阴虚感冒的口服液的制备方法，其中，步骤2中所述浸提的时间为6-15天，浸提温度为30-40摄氏度。
3.如权利要求1所述的治疗阴虚感冒的口服液的制备方法，其中，步骤2中，采用旋蒸法使乙醇蒸发，旋蒸温度为50-55摄氏度。
4.如权利要求1所述的治疗阴虚感冒的口服液的制备方法，其中，步骤2中在浸提过程中每隔6-12小时进行超声震荡20-30分钟。
5.如权利要求1所述的治疗阴虚感冒的口服液的制备方法，其中，所述中药组合物包括以下重量份的原料：女贞子10、北沙参10、麦冬10、玉竹10、黄精10、枸杞子18、熟地10、白芍10、茯苓皮10、马鞭草10、玉米须18、泽泻10、青蒿10、胡黄莲10、十大功劳叶10、白薇10、紫苏18、防风10、荆芥9、生姜10、葱白18、菊花18、倒扣草10以及伤寒草10。
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CN104958445A (zh) * 2015-07-14 2015-10-07 青岛恒波仪器有限公司 一种防治风热上攻目赤肿痛的蔓荆子口服液及其制备方法
CN105435167A (zh) * 2015-12-10 2016-03-30 覃俊 一种治疗冬季感冒发烧的口服液的制备方法
CN106344893A (zh) * 2016-08-31 2017-01-25 王美玲 治疗气虚性感冒的口服液的制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104958445A (zh) * 2015-07-14 2015-10-07 青岛恒波仪器有限公司 一种防治风热上攻目赤肿痛的蔓荆子口服液及其制备方法
CN105435167A (zh) * 2015-12-10 2016-03-30 覃俊 一种治疗冬季感冒发烧的口服液的制备方法
CN106344893A (zh) * 2016-08-31 2017-01-25 王美玲 治疗气虚性感冒的口服液的制备方法

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