CN107184474A - A kind of Wrinkle-eliminating cosmetics and preparation method thereof - Google Patents

A kind of Wrinkle-eliminating cosmetics and preparation method thereof Download PDF

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CN107184474A
CN107184474A CN201710436007.1A CN201710436007A CN107184474A CN 107184474 A CN107184474 A CN 107184474A CN 201710436007 A CN201710436007 A CN 201710436007A CN 107184474 A CN107184474 A CN 107184474A
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parts
wrinkle
extract
water
glycerine
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程平
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Guangzhou Laosha Biological Technology Co Ltd
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Guangzhou Laosha Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/41Amines
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/42Amides
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    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
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    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645Proteins of vegetable origin; Derivatives or degradation products thereof
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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Abstract

The invention discloses a kind of Wrinkle-eliminating cosmetics, Wrinkle-eliminating cosmetics by weight, including polyethylene glycol 400, butanediol, propane diols, hydrolysis avenin, glycine betaine, ambrette extract, niacinamide, glycerine polymethacrylates, glycerine, cherry extract, panthenol, allantoin, Prunella vulgaris extract, Phenoxyethanol, carbomer, methyl hydroxybenzoate, triethanolamine, EDETATE SODIUM, Sodium Hyaluronate, phosphoglycerol inositol choline salt, the rilanit specials of PEG 40, CI 16255, essence, water.Invention additionally discloses a kind of preparation method of above-mentioned Wrinkle-eliminating cosmetics.Wrinkle-eliminating cosmetics of the present invention can effectively remove facial lines, improve elasticity of skin, and quality safety.

Description

A kind of Wrinkle-eliminating cosmetics and preparation method thereof
Technical field
The present invention relates to cosmetic field, more particularly to a kind of Wrinkle-eliminating cosmetics and preparation method thereof.
Background technology
Wrinkle is that skin is influenceed by age or external environment, the microgroove occurred gradually, and facial wrinkles are divided into atrophy wrinkle Line and loose wrinkle.With the increase at age, skin is gradually followed the string, and metabolic ability slowly weakens, and skin can be got over Carry out more aging, wrinkle is produced therewith, wrinkle is that skin lacks moisture, surface fat reduction, the result of flexibility decrease.Wrinkle goes out The appearance of face is now directly affected, at present, the cosmetics species for microgroove of dispelling is various, but microgroove effect of dispelling is general, and there is safety How sex chromosome mosaicism, therefore, provide a kind of good and safe Wrinkle-eliminating cosmetics of microgroove effect of dispelling, have very important significance.
The content of the invention
The present invention solves the technical problem of provide a kind of Wrinkle-eliminating cosmetics and preparation method thereof, the smoothing wrinkle of preparation Cosmetic can effectively remove facial lines, improve elasticity of skin, and quality safety.
In order to solve the above technical problems, the present invention provides a kind of Wrinkle-eliminating cosmetics, Wrinkle-eliminating cosmetics by weight, including 5-16 parts of PEG-4000s, 4-10 parts of butanediols, 2-8 parts of propane diols, 2-10 parts of hydrolysis avenins, 1-8 parts of glycine betaines, 1- 6 portions of ambrette extracts, 0.6-5 portions of niacinamide, 1-6 portions of glycerine polymethacrylates, 1-5 portions of glycerine, 1-5 portions of cherries are extracted Thing, 0.2-2 part panthenol, 0.1-0.3 parts of allantoins, 0.1-1 parts of Prunella vulgaris extracts, 0.1-1 parts of Phenoxyethanols, 0.05-0.5 parts Carbomer, 0.05-0.2 part methyl hydroxybenzoate, 0.05-0.5 parts of triethanolamines, 0.02-0.2 parts of EDETATE SODIUMs, 0.02-0.3 parts thoroughly The sour sodium of bright matter, 0.02-1 parts of phosphoglycerol inositol choline salts, 0.01-0.1 parts of Cremophor RH40s, 0.0001-0.003 parts CI 16255,0.004-0.03 part essence, 45-75 parts of water.
Wherein, ambrette extract is ambrette seed extract.
Wherein, Wrinkle-eliminating cosmetics by weight, including 10 parts of PEG-4000s, 7 parts of butanediols, 5 parts of propane diols, 6 Part hydrolysis avenin, 5 parts of glycine betaines, 4 parts of ambrette extracts, 3 parts of niacinamide, 3 parts of glycerine polymethacrylates, 3 parts it is sweet Oil, 3 parts of cherry extracts, 1 part of panthenol, 0.2 part of allantoin, 0.5 part of Prunella vulgaris extract, 0.5 part of Phenoxyethanol, 0.3 part of card Ripple nurse, 0.1 part of methyl hydroxybenzoate, 0.3 part of triethanolamine, 0.1 part of EDETATE SODIUM, 0.1 part of Sodium Hyaluronate, 0.5 part of phosphoglycerol Inositol choline salt, 0.05 part of Cremophor RH40,0.001 part of CI 16255,0.01 part of essence, 60 parts of water.
Wherein, PEG-4000, butanediol, propane diols, glycine betaine, glycerine polymethacrylates, glycerine, panthenol are NMF.
Wherein, hydrolysis avenin, ambrette extract, niacinamide, cherry extract, allantoin, Prunella vulgaris extract, thoroughly The sour sodium of bright matter, phosphoglycerol inositol choline salt are skin conditioning agent.
Wherein, carbomer is thickener;Triethanolamine is PH conditioning agents;Phenoxyethanol, methyl hydroxybenzoate are preservative;EDTA Disodium is chelating agent;CI 16255 is colouring agent;Cremophor RH40 is solubilizer;Essence is aromatic;Water is solvent.
In order to solve the above technical problems, the present invention provides a kind of preparation method of above-mentioned Wrinkle-eliminating cosmetics, including following step Suddenly:The each component of Wrinkle-eliminating cosmetics is weighed by weight;By PEG-4000, butanediol, propane diols, glycine betaine, niacinamide, Glycerine polymethacrylates, glycerine, panthenol, allantoin, Prunella vulgaris extract, Phenoxyethanol, methyl hydroxybenzoate, EDETATE SODIUM, Water is stirred, wherein, the consumption of water is the 90% of water inventory, is heated to 80-85 DEG C, is stirred 30-40 minutes with 20rpm-30rpm, and Insulation 0.3-0.6 hours, it is stand-by as aqueous phase;By carbomer, Sodium Hyaluronate, water stirring, wherein, the consumption of water is water inventory 10%, be heated to 45-55 DEG C, be uniformly dispersed, as pre-dispersed mutually stand-by;Aqueous phase is added to by pre-dispersed, stops heating, with 25rpm-35rpm is stirred 30-40 minutes;35-38 DEG C is cooled to, hydrolysis avenin, ambrette extract, cherry is added and extracts Thing, triethanolamine, phosphoglycerol inositol choline salt, Cremophor RH40, essence, CI 16255, stir, and filtering was both Obtain Wrinkle-eliminating cosmetics.
Wherein, pre-dispersed phase and aqueous phase are cooled to 36 DEG C.
The beneficial effects of the invention are as follows:Be different from the situation of prior art, Wrinkle-eliminating cosmetics of the invention by weight, Including 5-16 parts of PEG-4000s, 4-10 portions of butanediols, 2-8 portions of propane diols, 2-10 portions of hydrolysis avenins, 1-8 portions of beets Alkali, 1-6 portions of ambrette extracts, 0.6-5 portions of niacinamide, 1-6 portions of glycerine polymethacrylates, 1-5 portions of glycerine, 1-5 portions of cherries Extract, 0.2-2 part panthenol, 0.1-0.3 parts of allantoins, 0.1-1 parts of Prunella vulgaris extracts, 0.1-1 parts of Phenoxyethanols, 0.05- 0.5 part of carbomer, 0.05-0.2 parts of methyl hydroxybenzoates, 0.05-0.5 parts of triethanolamines, 0.02-0.2 parts of EDETATE SODIUMs, 0.02-0.3 Part Sodium Hyaluronate, 0.02-1 parts of phosphoglycerol inositol choline salts, 0.01-0.1 parts of Cremophor RH40s, 0.0001- 0.003 part of CI 16255,0.004-0.03 part essence, 45-75 parts of water.Above-mentioned Wrinkle-eliminating cosmetics can effectively remove facial lines, And quality safety.Wrinkle-eliminating cosmetics of the present invention have the characteristics that:Ambrette extract can protect fibroblast growth factor FGF-2, promotes the synthesis of collagen and glycosaminoglycan, keeps skin corium density, and plentiful, consolidation skin improves elasticity of skin, Smooth skin deep wrinkles;Can be releived scaly dry skin, tight, water profit moisturizing;Can effectively maintenance skin stratum corneum barrier, and with anti- Oxidation;Preparation method is simple, production equipment is lost small, cost performance height.
Embodiment
Embodiment 1
The present embodiment Wrinkle-eliminating cosmetics by weight, including 10 parts of PEG-4000s, 7 parts of butanediols, 5 parts of propane diols, 6 parts Hydrolyze avenin, 5 parts of glycine betaines, 4 parts of ambrette extracts, 3 parts of niacinamide, 3 parts of glycerine polymethacrylates, 3 parts of glycerine, 3 parts of cherry extracts, 1 part of panthenol, 0.2 part of allantoin, 0.5 part of Prunella vulgaris extract, 0.5 part of Phenoxyethanol, 0.3 part of card ripple Nurse, 0.1 part of methyl hydroxybenzoate, 0.3 part of triethanolamine, 0.1 part of EDETATE SODIUM, 0.1 part of Sodium Hyaluronate, 0.5 part of phosphoglycerol flesh Alcohol choline salt, 0.05 part of Cremophor RH40,0.001 part of CI 16255,0.01 part of essence, 60 parts of water.
Wherein, ambrette extract is the material being obtained by extraction from ambrette seed.
The preparation method of above-mentioned Wrinkle-eliminating cosmetics is as follows:
A. each component of Wrinkle-eliminating cosmetics is weighed by weight.
B. by PEG-4000, butanediol, propane diols, glycine betaine, niacinamide, glycerine polymethacrylates, sweet Oil, panthenol, allantoin, Prunella vulgaris extract, Phenoxyethanol, methyl hydroxybenzoate, EDETATE SODIUM, water stirring, wherein, the consumption of water is The 90% of water inventory, is heated to 83 DEG C, is stirred 35 minutes with 25rpm, and is incubated 0.4 hour, stand-by as aqueous phase.
C. carbomer, Sodium Hyaluronate, water are stirred, wherein, the consumption of water is the 10% of water inventory, is heated to 50 DEG C, It is uniformly dispersed, as pre-dispersed mutually stand-by.
D. aqueous phase is added to by pre-dispersed, stops heating, stirred 35 minutes with 30rpm.
E. 36 DEG C are cooled to, hydrolysis avenin, ambrette extract, cherry extract, triethanolamine, glycerine phosphorus is added Sour inositol choline salt, Cremophor RH40, essence, CI 16255, stir, and filtering both obtains Wrinkle-eliminating cosmetics.
In the present embodiment, PEG-4000, butanediol, propane diols, glycine betaine, glycerine polymethacrylates, sweet Oil, panthenol are NMF;Avenin, ambrette extract, niacinamide, cherry extract, allantoin, selfheal is hydrolyzed to extract Thing, Sodium Hyaluronate, phosphoglycerol inositol choline salt are skin conditioning agent;Carbomer is thickener;Triethanolamine is adjusted for PH Agent;Phenoxyethanol, methyl hydroxybenzoate are preservative;EDETATE SODIUM is chelating agent;CI 16255 is colouring agent;PEG-40 hydrogenated castors Oil is solubilizer;Essence is aromatic;Water is solvent.
Illustrate the wrinkle improvement effect of the present embodiment Wrinkle-eliminating cosmetics below by specific experiment.
30-55 Sui 100 women are chosen, continuously the present embodiment Wrinkle-eliminating cosmetics on probation 30 days, specifically, clean skin skin toner Afterwards, appropriate Wrinkle-eliminating cosmetics are taken to be applied to face and be gently massaged into absorption, once in the morning and once at night.After off-test, subject is observed Wrinkle improvement effect, specially observe subject face(Eye, forehead, other)Microgroove, which improves situation and skin elasticity, improves feelings Condition, wherein, improving situation is included without improvement, slight, obvious Three Estate.
Facial lines result of the test:Eye(Without improvement, 3%;Slightly, 36%;Substantially, 61%), forehead(Without improvement, 2%;Gently It is micro-, 45%;Substantially, 53%), other(Without improvement, 1%;Slightly, 38%;Substantially, 61%).Skin elasticity result of the test:Without improvement, 1%;Slightly, 33%;Substantially, 66%.And in process of the test, do not occur any side effect and excitant phenomenon.According to experiment knot Really, it can be seen that the present embodiment goes cosmetics effectively to remove facial wrinkles, and quality safety.
Embodiment 2
The present embodiment Wrinkle-eliminating cosmetics by weight, including 12 parts of PEG-4000s, 8 parts of butanediols, 6 parts of propane diols, 5 parts Hydrolyze avenin, 6 parts of glycine betaines, 5 parts of ambrette extracts, 2 parts of niacinamide, 2 parts of glycerine polymethacrylates, 4 parts of glycerine, 4 parts of cherry extracts, 1.5 parts of panthenols, 0.2 part of allantoin, 0.3 part of Prunella vulgaris extract, 0.3 part of Phenoxyethanol, 0.2 part of card ripple Nurse, 0.15 part of methyl hydroxybenzoate, 0.15 part of triethanolamine, 0.08 part of EDETATE SODIUM, 0.2 part of Sodium Hyaluronate, 0.06 part of glycerine phosphorus Sour inositol choline salt, 0.06 part of Cremophor RH40,0.002 part of CI 16255,0.02 part of essence, 65 parts of water.
Wherein, ambrette extract is the material being obtained by extraction from ambrette seed.
The preparation method of above-mentioned Wrinkle-eliminating cosmetics is as follows:
A. each component of Wrinkle-eliminating cosmetics is weighed by weight.
B. by PEG-4000, butanediol, propane diols, glycine betaine, niacinamide, glycerine polymethacrylates, sweet Oil, panthenol, allantoin, Prunella vulgaris extract, Phenoxyethanol, methyl hydroxybenzoate, EDETATE SODIUM, water stirring, wherein, the consumption of water is The 90% of water inventory, is heated to 83 DEG C, is stirred 35 minutes with 25rpm, and is incubated 0.4 hour, stand-by as aqueous phase.
C. carbomer, Sodium Hyaluronate, water are stirred, wherein, the consumption of water is the 10% of water inventory, is heated to 50 DEG C, It is uniformly dispersed, as pre-dispersed mutually stand-by.
D. aqueous phase is added to by pre-dispersed, stops heating, stirred 35 minutes with 30rpm.
E. 36 DEG C are cooled to, hydrolysis avenin, ambrette extract, cherry extract, triethanolamine, glycerine phosphorus is added Sour inositol choline salt, Cremophor RH40, essence, CI 16255, stir, and filtering both obtains Wrinkle-eliminating cosmetics.
In the present embodiment, PEG-4000, butanediol, propane diols, glycine betaine, glycerine polymethacrylates, sweet Oil, panthenol are NMF;Avenin, ambrette extract, niacinamide, cherry extract, allantoin, selfheal is hydrolyzed to extract Thing, Sodium Hyaluronate, phosphoglycerol inositol choline salt are skin conditioning agent;Carbomer is thickener;Triethanolamine is adjusted for PH Agent;Phenoxyethanol, methyl hydroxybenzoate are preservative;EDETATE SODIUM is chelating agent;CI 16255 is colouring agent;PEG-40 hydrogenated castors Oil is solubilizer;Essence is aromatic;Water is solvent.
Illustrate the wrinkle improvement effect of the present embodiment Wrinkle-eliminating cosmetics below by specific experiment.
30-55 Sui 100 women are chosen, continuously the present embodiment Wrinkle-eliminating cosmetics on probation 30 days, specifically, clean skin skin toner Afterwards, appropriate Wrinkle-eliminating cosmetics are taken to be applied to face and be gently massaged into absorption, once in the morning and once at night.After off-test, subject is observed Wrinkle improvement effect, specially observe subject face(Eye, forehead, other)Microgroove, which improves situation and skin elasticity, improves feelings Condition, wherein, improving situation is included without improvement, slight, obvious Three Estate.
Facial lines result of the test:Eye(Without improvement, 3%;Slightly, 37%;Substantially, 60%), forehead(Without improvement, 2%;Gently It is micro-, 47%;Substantially, 51%), other(Without improvement, 1%;Slightly, 39%;Substantially, 60%).Skin elasticity result of the test:Without improvement, 1%;Slightly, 34%;Substantially, 65%.And in process of the test, do not occur any side effect and excitant phenomenon.According to experiment knot Really, it can be seen that the present embodiment goes cosmetics effectively to remove facial wrinkles, and quality safety.
In summary, Wrinkle-eliminating cosmetics of the present invention can effectively remove facial lines, improve elasticity of skin, and quality safety.
Embodiments of the invention are the foregoing is only, are not intended to limit the scope of the invention, it is every to utilize this hair The equivalent transformation that bright description is made, or other related technical fields are directly or indirectly used in, similarly it is included in In the scope of patent protection of the present invention.

Claims (8)

1. a kind of Wrinkle-eliminating cosmetics, it is characterised in that the Wrinkle-eliminating cosmetics by weight, including 5-16 parts of polyethylene glycol- 400th, 4-10 parts of butanediols, 2-8 parts of propane diols, 2-10 parts of hydrolysis avenins, 1-8 parts of glycine betaines, 1-6 parts of ambrette extracts, 0.6-5 parts of niacinamide, 1-6 parts of glycerine polymethacrylates, 1-5 parts of glycerine, 1-5 parts of cherry extracts, 0.2-2 parts of panthenols, 0.1-0.3 parts of allantoins, 0.1-1 parts of Prunella vulgaris extracts, 0.1-1 parts of Phenoxyethanols, 0.05-0.5 parts of carbomers, 0.05-0.2 Part methyl hydroxybenzoate, 0.05-0.5 parts of triethanolamines, 0.02-0.2 parts of EDETATE SODIUMs, 0.02-0.3 parts of Sodium Hyaluronates, 0.02-1 Part phosphoglycerol inositol choline salt, 0.01-0.1 parts of Cremophor RH40s, 0.0001-0.003 parts of CI 16255,0.004- 0.03 part of essence, 45-75 parts of water.
2. Wrinkle-eliminating cosmetics according to claim 1, it is characterised in that the ambrette extract extracts for ambrette seed Thing.
3. Wrinkle-eliminating cosmetics according to claim 2, it is characterised in that the Wrinkle-eliminating cosmetics by weight, including 10 parts of PEG-4000s, 7 parts of butanediols, 5 parts of propane diols, 6 parts of hydrolysis avenins, 5 parts of glycine betaines, 4 parts of ambrette extracts, 3 parts of niacinamide, 3 parts of glycerine polymethacrylates, 3 parts of glycerine, 3 parts of cherry extracts, 1 part of panthenol, 0.2 part of allantoin, 0.5 Part Prunella vulgaris extract, 0.5 part of Phenoxyethanol, 0.3 part of carbomer, 0.1 part of methyl hydroxybenzoate, 0.3 part of triethanolamine, 0.1 part EDETATE SODIUM, 0.1 part of Sodium Hyaluronate, 0.5 part of phosphoglycerol inositol choline salt, 0.05 part of Cremophor RH40,0.001 Part CI 16255,0.01 part of essence, 60 parts of water.
4. Wrinkle-eliminating cosmetics according to claim 2, it is characterised in that the PEG-4000, butanediol, the third two Alcohol, glycine betaine, glycerine polymethacrylates, glycerine, panthenol are NMF.
5. Wrinkle-eliminating cosmetics according to claim 4, it is characterised in that the hydrolysis avenin, ambrette extract, cigarette Acid amides, cherry extract, allantoin, Prunella vulgaris extract, Sodium Hyaluronate, phosphoglycerol inositol choline salt are skin condition Agent.
6. Wrinkle-eliminating cosmetics according to claim 5, it is characterised in that the carbomer is thickener;Triethanolamine is PH conditioning agents;Phenoxyethanol, methyl hydroxybenzoate are preservative;EDETATE SODIUM is chelating agent;CI 16255 is colouring agent;PEG-40 hydrogen Change castor oil is solubilizer;Essence is aromatic;Water is solvent.
7. the preparation method of the Wrinkle-eliminating cosmetics described in claim 1-6 any one, it is characterised in that comprise the following steps:
The each component of Wrinkle-eliminating cosmetics is weighed by weight;
By PEG-4000, butanediol, propane diols, glycine betaine, niacinamide, glycerine polymethacrylates, glycerine, panthenol, Allantoin, Prunella vulgaris extract, Phenoxyethanol, methyl hydroxybenzoate, EDETATE SODIUM, water stirring, wherein, the consumption of water is water inventory 90%, 80-85 DEG C is heated to, is stirred 30-40 minutes with 20rpm-30rpm, and 0.3-0.6 hours are incubated, it is stand-by as aqueous phase;
By carbomer, Sodium Hyaluronate, water stirring, wherein, the consumption of water is the 10% of water inventory, is heated to 45-55 DEG C, is disperseed Uniformly, as pre-dispersed mutually stand-by;
Aqueous phase is added to by pre-dispersed, stops heating, is stirred 30-40 minutes with 25rpm-35rpm;
35-38 DEG C is cooled to, hydrolysis avenin, ambrette extract, cherry extract, triethanolamine, phosphoglycerol flesh is added Alcohol choline salt, Cremophor RH40, essence, CI 16255, stir, and filtering both obtains Wrinkle-eliminating cosmetics.
8. preparation method according to claim 7, it is characterised in that the pre-dispersed phase and aqueous phase are cooled to 36 DEG C.
CN201710436007.1A 2017-06-12 2017-06-12 A kind of Wrinkle-eliminating cosmetics and preparation method thereof Pending CN107184474A (en)

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CN113712877A (en) * 2021-09-30 2021-11-30 广东美思康宸药业股份有限公司 Nicotinamide chamomile skin-beautifying mask liquid and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN110507594A (en) * 2019-09-17 2019-11-29 上海百雀羚生物科技有限公司 A kind of toner and preparation method thereof
CN110507594B (en) * 2019-09-17 2022-06-17 上海百雀羚生物科技有限公司 Toning lotion and preparation method thereof
CN112791035A (en) * 2021-01-18 2021-05-14 广州市莲娜姬化妆品有限公司 Anti-wrinkle skin care product composition and preparation method thereof
CN113712877A (en) * 2021-09-30 2021-11-30 广东美思康宸药业股份有限公司 Nicotinamide chamomile skin-beautifying mask liquid and preparation method thereof

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