CN107158446A - The hemostasis of the composite active carbon fibre of class containing only iridoid glycoside, antibacterial, promoting healing medical dressing, Preparation method and use - Google Patents

The hemostasis of the composite active carbon fibre of class containing only iridoid glycoside, antibacterial, promoting healing medical dressing, Preparation method and use Download PDF

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Publication number
CN107158446A
CN107158446A CN201710315415.1A CN201710315415A CN107158446A CN 107158446 A CN107158446 A CN 107158446A CN 201710315415 A CN201710315415 A CN 201710315415A CN 107158446 A CN107158446 A CN 107158446A
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hemostasis
dressing
iridoid glycoside
active carbon
antibacterial
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李曹龙
王飞
戚彩玉
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China Pharmaceutical University
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China Pharmaceutical University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention discloses a kind of hemostasis, antibacterial, the promoting healing dressing of the composite medical NACF of active component containing only iridoid glycoside (ACF), belongs to medical dressing preparing technical field, is made up of the composition of following percentage by weight：1~20% only iridoid glycoside class, 0.01~1% hexadecyltrimethylammonium chloride, 1~5% polyvinyl alcohol or collagen, surplus are medical activated carbon fibre substrate.The present invention makes solution dosage, gel preparations and medical activated carbon fiber composite by the combination such as iridoid glycoside active component in lamiophlomis rotata and polyvinyl alcohol or collagen and is prepared into external medical dressing series.Using the absorption surface of a wound exudates of ACF by force, clotting mechanism is activated, accelerates the effect of hemostasis.Play therebetween " cooperative effect ", can be used for treatment infected wound, surgery wound bleeding etc., with good hemostasis, antibacterial, promoting healing performance, have broad application prospects.Rationally, it is convenient to prepare for inventive formulation, controls trauma surface infestation, wound healing is verified through artery, abdominal aortic and people's mouse liver surface of a wound hemostasis model in large ear rabbit ear, efficient up to more than 95%.

Description

The hemostasis of the composite active carbon fibre of class containing only iridoid glycoside, antibacterial, promoting healing Medical dressing, Preparation method and use
Technical field
It is related to a kind of activity of class containing only iridoid glycoside the present invention relates to a kind of plant medical material, especially one kind The hemostasis of composition composite active carbon fibre, antibacterial, promoting healing medical dressing, preparation method and its usage, it is adaptable to various wounds Treatments for bleeding.
Background technology
It is as new NACF current situation activated carbon fiber (activated carbon fiber, ACF) dressing In recent years the another novel high polymer medical dressing developed.Big with specific surface area, effective adsorption capacity is high, adsorption and desorption speed It hurry up, easily regeneration, dust burdening is low, and chemical stability is strong, good pliability and intensity.The strong suction-operated of activated carbon fiber and table There are a variety of functional groups in face, can occur redox reaction with a variety of clotting factor in the surface of a wound, clotting mechanism be activated, with adding The effect of short stopping blood.The microcellular structure that NACF dressing is enriched by the powerful adsorptivity of its activated carbon fiber and surface, Tissue fluid, pus, bacterium and pathogenic microorganisms are sucked in micropore, changing living environment makes it dead, mitigate inflammatory reaction, plus Fast wound healing.
In order to prevent wound infection, conventional many medical dressing add antibiotic when using, and antibiotic is long-term big Dosage use can produce drug resistance, even to this day, and some bacteriums have been difficult to be killed with antibiotic.In the spy using core chemical and biological weapons Under different war condition, the surface of a wound pollution condition of the wounded is likely more complexity, and the treatment for being further exacerbated by the infected wound surface of a wound is difficult Degree.The scene wrapping hemostasis and preventing and treating infection of the tissue surface of a wound are the first steps of emergency care of trauma.Selection wrapping of good performance is applied Material can effectively improve the efficiency of surface of a wound hemostasis and reduce the incidence of forth infection complication.Existing hemostatic is various in style, Mechanism is complicated, but the research one of new haemostatic medicament is directly subordinate to hot issue.The haemostatic medicament of plant origin, from traditional national medicine The composition that developmental research has good styptic activity in thing still has unique advantage and infinite potentiality.
Lamiophlomis rotata is Labiatae lamiophlomis rotata platymiscium, root and all herbal medicine.With promoting blood circulation and stopping pain, change effect of addiction hemostasis； For the edge of a knife pain bleeding of a variety of surgical site infections, muscles and bones is sprained, and exogenous injury, dysmenorrhoea, uterine bleeding, swelling and aching of gum, rheumatism is fought Bitterly.Put into practice through long term medical among the people, determined curative effect, security is good.Iridoid glycosides is hemostatic analgesia validation in lamiophlomis rotata Study point.It is the water-soluble preferably compound of a class that cyclenes ether, which covers methods of glycosides, and Radix Lamiophlomidis Rotatae total iridoid glycosides powder not only has There is good promotion surface of a wound hemostasis-coagulation effect, also present preferable water imbibition and adhesion property.Good water imbibition can Rapid concentration blood, aggregation blood platelet and fibrin, accelerate blood coagulation.The adhesiveness of strength can then block wound well Mouthful, be conducive to the attachment of blood clotting, being unlikely to come off causes secondary bleeding.The constituents can be by the tissue in the surface of a wound simultaneously Liquid slow mechanism dissolved simultaneously absorbs, and local inflammation will not be caused to stimulate, be conducive to wound repair.
In view of above-mentioned background, the present inventor is by total iridoid glycoside active component anthemorrhagic performance and medicinal active in lamiophlomis rotata Carbon fiber organically combine, play " cooperative effect " of the two, to develop have hemostasis, antibacterial, promoting healing drug effect only one Taste total iridoid glycoside composite active carbon fibre medical dressing.
The content of the invention
It is a primary object of the present invention to, the defect for overcoming existing dressing to exist, and provide a kind of new containing lamiophlomis rotata Hemostasis, antibacterial, promoting healing medical dressing, preparation method and its use of iridoid glycoside active component composite active carbon fibre On the way, hemostatic height, can quick-acting haemostatic powder, wound easily heals adhesion, good biocompatibility；Anti- drawing ability and the close attached power of tissue It is good, it is non-breakable.
The object of the invention to solve the technical problems is realized using following technical scheme.According to present invention proposition The hemostasis of the composite active carbon fibre of active component containing only iridoid glycoside, antibacterial, promoting healing medical dressing, by as follows The composition composition of percentage by weight：1~20% only iridoid glycoside class, 0.01~1% hexadecyltrimethylammonium chloride, 1~5% polyvinyl alcohol or collagen, surplus are medical activated carbon fibre substrate.
The hemostasis of the foregoing composite active carbon fibre of active component containing only iridoid glycoside, antibacterial, promoting healing doctor With dressing, the formulation of the dressing is sprayed on formation external patch formulation on medicinal active Carbon fibe for active component wiring solution-forming.
The hemostasis of the foregoing composite active carbon fibre of active component containing only iridoid glycoside, antibacterial, promoting healing doctor With dressing, the formulation of the dressing is made into the external use plaster that cream smears NACF for active component.The emulsifiable paste of use Agent composition is made up of the composition of following parts by weight, iridoid glycoside (some), octadecyl alcolol (1.8g), SDS (0.2g), albolene (2g), Buddhist nun's pool ethyl ester is golden (0.02g), atoleine (1.2g), glycerine (0.1ml), beeswax (3.3g), vegetable oil (7.4ml), carboxylic Sodium carboxymethylcellulose pyce (1.2g), the sodium benzoate aqueous solution (16.8ml), purified water is some.
The composite active carbon fibre of active component containing only iridoid glycoside hemostasis, antibacterial, promoting healing medical dressing Preparation method, including following operating procedure, by the iridoid glycoside constituents extracted from lamiophlomis rotata, stabilizer and poly- second After enol or a kind of collagen mixed dissolution therein, it is dissolved in matrix, then filling in packing container, irradiation sterilization Afterwards, solution dosage dressing or ointment dosage form dressing are obtained.
The hemostasis of the foregoing composite active carbon fibre of active component containing only iridoid glycoside, antibacterial, promoting healing doctor With the preparation method of dressing, the solution dosage dressing of preparation is sprayed on medicinal active Carbon fibe, after drying, irradiation sterilization, Obtain dressing type outer patch solid dressing.
The hemostasis of the foregoing composite active carbon fibre of active component containing only iridoid glycoside, antibacterial, promoting healing doctor With the preparation method of dressing, the ointment dosage form dressing of preparation is applied on NACF, after drying, irradiation sterilization obtains deposited Material type outer patch solid dressing.
The hemostasis of the composite active carbon fibre of active component containing only iridoid glycoside, antibacterial, promoting healing medical dressing For various protecting wound surfaces caused by wound and operative hemorrhage hemostasis and burn, infection etc., control trauma surface infestation, the promotion surface of a wound Healing.
By above-mentioned technical proposal, the composite active carbon fibre of active component containing only iridoid glycoside of the invention only Blood, antibacterial, promoting healing medical dressing, preparation method and its usage at least have following advantages：
Lamiophlomis rotata is Labiatae lamiophlomis rotata platymiscium, root and all herbal medicine.With promoting blood circulation and stopping pain, change effect of addiction hemostasis； For the edge of a knife pain bleeding of a variety of surgical site infections, muscles and bones is sprained, and exogenous injury, dysmenorrhoea, uterine bleeding, swelling and aching of gum, rheumatism is fought Bitterly.The specific surface area of binding activity Carbon fibe is big, and effective adsorption capacity is high, and adsorption and desorption speed is fast, easily regeneration, and dust burdening is low, The advantages of chemical stability is strong, plays cooperative effect, can be used for treatment infected wound, surgery wound etc., anti-microbial property is good It is good, have broad application prospects.Rationally, it is convenient to prepare, and controls trauma surface infestation for inventive formulation, keeps surface of a wound moistening, promotes Wound healing, verifies that effective percentage reaches through artery, abdominal aortic and people's mouse liver surface of a wound hemostasis model in large ear rabbit ear More than 95%.
Described above is only the general introduction of technical solution of the present invention, in order to better understand the technological means of the present invention, And can be practiced according to the content of specification, described in detail below with presently preferred embodiments of the present invention as after.
Embodiment
Further to illustrate the present invention to reach the technological means and effect that predetermined goal of the invention is taken, to according to this The hemostasis for the composite active carbon fibre of active component containing only iridoid glycoside that invention is proposed, antibacterial, promoting healing Medical coating Material, preparation method and its usage its embodiment, feature and its effect, are described in detail as after.
Embodiment 1
The hemostasis of the composite active carbon fibre of active component containing only iridoid glycoside of the invention, antibacterial, promoting healing doctor With dressing, it is made up of the composition of following weight percents：Iridoid glycosides (15%), the stabilizer ten extracted from lamiophlomis rotata Six alkyl trimethyl ammonium chlorides (0.5%), polyvinyl alcohol (5%), purified water are some.
External application type solid medical dressing preparation method：By only iridoid glycoside active component, stabilizer and poly- second It is miscible that liquid flux is made into purified water after enol mixed dissolution, it is sprayed on medicinal active Carbon fibe, after drying, irradiation Sterilization, obtains external application type solid medical dressing
Product is for various protecting wound surfaces, control caused by wound and operative hemorrhage hemostasis and burn, infection etc. Trauma surface infestation, wound healing.

Claims (6)

1. a kind of hemostasis of the composite active carbon fibre of class containing only iridoid glycoside, antibacterial, promoting healing medical dressing, its feature It is：It is made up of the composition of following percentage by weight：1~20% only iridoid glycoside class, 0.01~1% cetyl three Ammonio methacrylate, 1~5% polyvinyl alcohol or collagen, surplus is matrix.It is sprayed at medicinal active Carbon fibe (ACF) On, reach performance the two " cooperative effect ".
2. the hemostasis of the composite active carbon fibre of class containing only iridoid glycoside according to claim 1, antibacterial, promoting healing Medical dressing, it is characterised in that：The background formulation of the dressing is solution dosage, and the matrix used is purified water.
3. the hemostasis of the composite active carbon fibre of class containing only iridoid glycoside according to claim 1, antibacterial, promoting healing Medical dressing, it is characterised in that：The background formulation of the dressing is ointment dosage form, and the matrix components of use are by following parts by weight Composition is constituted, octadecyl alcolol (1.8g), SDS (0.2g), albolene (2g), and Buddhist nun's pool ethyl ester is golden (0.02g), atoleine (1.2g), glycerine (0.1ml), beeswax (3.3g), vegetable oil (7.4ml), sodium carboxymethylcellulose (1.2g), sodium benzoate is water-soluble Liquid (16.8ml), purified water is some.
4. a kind of composite active carbon fibre of class containing only iridoid glycoside hemostasis, antibacterial, promoting healing medical dressing, its feature exist In：Including following operating procedure, by the iridoid glycoside active component extracted from lamiophlomis rotata, cetyl trimethyl chlorination Ammonium is with after polyvinyl alcohol or a kind of collagen mixed dissolution therein, being dissolved in matrix, then filling in packing container, spoke After sterilization, solution dosage dressing or ointment dosage form dressing are obtained.
5. the system of the hemostasis medical dressing of the composite active carbon fibre of class containing only iridoid glycoside according to claim 4 Preparation Method, it is characterised in that：The solution dosage of preparation or ointment dosage form dressing are sprayed on NACF (ACF), dried Afterwards, irradiation sterilization, obtains dressing type solid dressing.
6. the hemostasis medical dressing of the composite active carbon fibre of class containing only iridoid glycoside be used for protect burn, wound, operation, The various surface of a wound caused by infection, suppress bleeding, control trauma surface infestation, wound healing.
CN201710315415.1A 2017-05-02 2017-05-02 The hemostasis of the composite active carbon fibre of class containing only iridoid glycoside, antibacterial, promoting healing medical dressing, Preparation method and use Pending CN107158446A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108159114A (en) * 2018-01-23 2018-06-15 重庆医科大学 Radix Lamiophlomidis Rotatae total iridoid glycosides extract, extracting method and its application
CN108159114B (en) * 2018-01-23 2021-07-27 重庆医科大学 Lamiophlomis rotata total iridoid glycoside extract, extraction method and application thereof

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Application publication date: 20170915