CN107156150A - A kind of avermectin B2a micro-capsule synergy suspending agent and preparation method thereof - Google Patents
A kind of avermectin B2a micro-capsule synergy suspending agent and preparation method thereof Download PDFInfo
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- CN107156150A CN107156150A CN201710383869.2A CN201710383869A CN107156150A CN 107156150 A CN107156150 A CN 107156150A CN 201710383869 A CN201710383869 A CN 201710383869A CN 107156150 A CN107156150 A CN 107156150A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
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Abstract
The present invention relates to avermectin B2a micro-capsule synergy suspending agent, include the following component of percentage by weight：Avermectin B2a 2% 50%, microcapsule controlled-release agent 0.2% 5%, dispersion moisture agent 3% 5%, thickener 0.1% 1%, preservative 0.1%, antifreezing agent 3% 5%, defoamer 0.1%, synergist 0.2% 5% and surplus are water；Avermectin B2a, microcapsule controlled-release agent, dispersant wetting agent, thickener, preservative, antifreezing agent, defoamer, synergist and water are subjected to premix shearing, then carry out two grades being sanded into product.The avermectin B2a micro-capsule synergy suspending agent surface tension of the present invention is low, good drug efficacy, the lasting period is long, and preparation technology is simple, application method is simple, shows the avermectin B2a microcapsule controlled-release synergy suspending agent of the present invention in holding effect by field experiment and quick-acting has significant insecticidal effect.
Description
Technical field
The invention belongs to pesticide production technology field, and in particular to a kind of avermectin B2a micro-capsule synergy suspending agent and its
Preparation method.
Background technology
AVM is a kind of f macrolide disaccharide compound, and tool is tagged, stomach poison function, and has very strong penetration.Ah
It is the ten hexa-atomic macrolides desinsection natural products produced by streptomycete fermentation, the wherein big component B1 of the one of homologue to tie up rhzomorph
And its derivative has realized commercialization, but agricultural chemicals drug resistance problems are also derived simultaneously, peasant household's usage amount is big, crop pests
The resistance to the action of a drug is stronger, therefore the preventive effect ability of the single dose Pesticidal products of AVERMECTIN B1 is more and more lower.The homologue of AVM is another
One big component B2a is higher than B1 to the virulence activity of some arthropods and non-digestive tract nematode, especially eats root nematode, Huang to corn
Meal beetle, B2a virulence is 3~5 times of B1.Avermectin B2a also non-commercial application so far both at home and abroad at present.
Avermectin B2a, English name：Avermectin B2a；Chemical name：Avermectin B2a：（13R, 23S）- 22,
23- dihydro -5-0- dimethyl -23- hydroxyl avermectin A1as；CAS accession number：65195-57-5（B2a）；Molecular weight：
891.1（B2a）；Molecular formula：C48H74O15（B2a）；Outward appearance：White or buff powder or crystallization；Fusing point：155℃ ~160
℃ ；Dissolubility：It is slightly soluble in water, more than 15 DEG C, the solubility in most organic solvents such as toluene, methanol, ethanol, DMF, acetone
It is high；Stability：In the aqueous solution of pH values 5 ~ 7（25℃）Middle stability is good；It is sensitive to strong acid and strong base.Avermectin B2a with
Activation nicotinic acetylcholine receptor is action site, causes the effects such as insect paralysis.Avermectin B2a structural formula is
Modern changes quickly, and the direction just towards environmental type is developed, and suspends and microcapsule suspending agent is exactly one of which,
Agricultural chemicals suspension agent and microcapsule suspending agent are that developing history is short in pesticidal preparations, a kind of very fast formulation, many herbicides,
Insecticidal bactericide can be processed into this formulation.Agricultural chemicals suspension agent and microcapsule suspending agent are using water as decentralized medium, insoluble or slightly soluble
In the ground crushing of the solid active compound of water, and by the effect of surfactant and other auxiliary agents, it is allowed to dispersed, forms one
The tiny higher suspension of particle, flowable more stable liquid solid-state system are planted, compared with missible oil, can avoid having using substantial amounts of
Machine solvent；Compared with wettable powder, then dispersed drift without dust；To the toxicity and excitant of people and animals all than relatively low；And can mitigate
Poisoning to crop；Also it will not be burnt because of organic solvent in storage transportation, security is higher；To user and whole ring
Danger caused by border is reduced at a fairly low degree.Also, agricultural chemicals suspension agent and microcapsule suspending agent excellent performance, dispersiveness
Good, suspensibility is high, and the exhibition on plant surface is puted forth effort and adhesion strength is all stronger, resistance of rainwater washing against, drug effect than more significant and
Compare persistently.Insecticides adjuvant domestic at present is not also very flourishing, also no small gap compared with developed countries, with existing
The suspending agent that auxiliary agent is made into is the problem of presence more or less in terms of physical stability is certain.
The content of the invention
The purpose of the present invention is to overcome defect present in above-mentioned prior art and provide a kind of avermectin B2a micro-capsule and increase
Suspending agent is imitated, the problem of microcapsule suspending agent quick-acting is poor, physical stability is poor is solved, makes the quick-acting and lasting effect of product
Greatly improve, more than ordinary preparation.
It is a further object of the present invention to provide the preparation method of avermectin B2a micro-capsule synergy suspending agent.
The purpose of the present invention is achieved through the following technical solutions：
A kind of avermectin B2a micro-capsule synergy suspending agent, is made up of the following component of percentage by weight：Avermectin B2a 2%-
50%, microcapsule controlled-release agent 0.2%-5%, dispersion moisture agent 5%-8%, thickener 0.1%-1%, preservative 0.1%, antifreezing agent 3%-5% disappear
Infusion 0.1%, synergist 0.2%-5%, surplus is water.
As a further improvement on the present invention, the synergist isopropyl myristate, makes the quick-acting and holding effect of product
Property is greatly improved, more than ordinary preparation；The dispersion moisture agent is selected from natural component sodium lauroyl glutamate, makes microcapsule controlled-release
Agent, synergist, active compound have carried out perfect combination, microcapsule controlled-release agent and synergist has been played maximum effect, substantially increase
The quick-acting of product and lasting period；The microcapsule controlled-release agent is carbomer；The thickener is the xanthan mixed with arbitrary proportion
Glue and Magnesiumaluminumsilicate；The antifreezing agent is ethylene glycol or propane diols；The defoamer is multi-polysiloxane, polyethers or n-octyl alcohol；
The preservative is sodium benzoate.
The present invention still further provides the preparation method of avermectin B2a micro-capsule synergy suspending agent：
（1）Water and the microcapsule controlled-release agent of amount of preparation are added in the container of stirring, is stirred, softgel shell is formed；
（2）Into above-mentioned softgel shell, add dispersion moisture agent and stir, add avermectin B2a active compound, stir, carry out
20000 revs/min of high speed shear 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, obtains material C；
（3）Thickener, preservative, antifreezing agent, defoamer, synergist are sequentially added into above-mentioned material C, is well mixed, then enter
The high speed shear of 12000 revs/min of row 20-50 minutes, obtains material D；
（4）Above-mentioned material D is subjected to two grades of sand millings, that is, obtains avermectin B2a micro-capsule synergy suspending agent.
Instant invention overcomes the cumbersome problem of traditional microcapsule suspending agent preparation technology, by microcapsule controlled-release agent, excess water, profit
Hygroscopic water powder is well mixed to can obtain micro-capsule, and addition active compound high speed shear, which can form softgel shell, must wrap up active compound, it is not necessary to
The complex processes such as polymerization are boiled in traditional handicraft, technique is simple；Solve avermectin B2a microcapsule controlled-release synergy suspending agent
Problem is prepared, the prevention effect of avermectin B2a suspending agent is improved by adding synergist, microcapsule controlled-release agent, with economy
With environment double benefit；By adding microcapsule controlled-release agent, the lasting period of avermectin B2a is delayed, by adding synergist meat
Isopropyl myristate, improves the prevention effect of the slow-releasing microcapsule suspending agent of avermectin B2a, less active compound consumption is reachable
To higher prevention effect, reduction manufacturing cost and cost of transportation；Avermectin B2a micro-capsule synergy suspending agent of the present invention is wide
Spectrum is efficient, safety low-poison, and the crop pests such as red spider, cotten aphid and pear sucker are efficient.
Embodiment
The present invention is described in further detail with reference to specific embodiment.
Embodiment 1
864 grams of water, 2 grams of the microcapsule controlled-release agent carbomer of surplus are added in the reactor for have stirring, is stirred, capsule is formed
Shell, then adds 50 grams of dispersion moisture agent sodium lauroyl glutamate and stirs, and adds the 20 grams of stirrings of avermectin B2a active compound equal
It is even, at a high speed（20000 revs/min）Shearing 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, then sequentially adds increasing
Thick dose of 2 grams of xanthans, 8 grams of aluminium-magnesium silicate, 50 grams of antifreeze glycol, 1 gram of defoamer polyethers, 1 gram of preservative sodium benzoate, increasing
Imitate 2 grams of agent isopropyl myristate to be well mixed, 12000 revs/min carry out high speed shear 20 minutes；Then two grades of sand are carried out
Mill, can obtain the sample one of 2% avermectin B2a micro-capsule synergy suspending agent.
Embodiment 2
531 grams of water, 30 grams of the microcapsule controlled-release agent carbomer of surplus are added in the reactor for have stirring, is stirred, capsule is formed
Shell, then adds 60 grams of dispersion moisture agent sodium lauroyl glutamate and stirs, and adds the 300 grams of stirrings of avermectin B2a active compound
Uniformly, at a high speed（20000 revs/min）Shearing 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, then sequentially adds
1 gram of xanthans, 5 grams of aluminium-magnesium silicate, 40 grams of antifreezing agent propane diols, 1 gram of many polysilanes of defoamer, 1 gram of preservative sodium benzoate, increasing
Imitate 30 grams of agent isopropyl myristate to be well mixed, 12000 revs/min carry out high speed shear 30 minutes；Then two grades of sand are carried out
Mill, can obtain the sample two of 30% avermectin B2a micro-capsule synergy suspending agent.
Embodiment 3
287 grams of water, 50 grams of the microcapsule controlled-release agent carbomer of surplus are added in the reactor for have stirring, is stirred, capsule is formed
Shell, then adds 80 grams of dispersion moisture agent sodium lauroyl glutamate and stirs, and adds the 500 grams of stirrings of avermectin B2a active compound
Uniformly, at a high speed（20000 revs/min）Shearing 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, then sequentially adds
0.5 gram of xanthans, 0.5 gram of aluminium-magnesium silicate, 30 grams of antifreezing agent propane diols, 1 gram of defoamer n-octyl alcohol, 1 gram of preservative sodium benzoate,
50 grams of synergist isopropyl myristate is well mixed, and 12000 revs/min carry out high speed shear 50 minutes；Then two grades are carried out
It is sanded, can obtain 50% avermectin B2a micro-capsule synergy suspending agent is sample three.
Comparative example 1
868 grams of water are added in the reactor for have stirring, stirring is opened, then sequentially adds dispersion moisture agent modified polycarboxylic acid salt
50 grams, 2 grams of thickener xanthans, 8 grams of aluminium-magnesium silicate, 50 grams of antifreeze glycol, 1 gram of defoamer polyethers, preservative benzoic acid
1 gram of sodium, 20 grams of avermectin B2a active compound are well mixed, and 12000 revs/min carry out high speed shear 20 minutes；Then two grades are carried out
It is sanded, can obtain 2% avermectin B2a suspending agent is sample four.
Comparative example 2
866 grams of water, 2 grams of the microcapsule controlled-release agent carbomer of surplus are added in the reactor for have stirring, is stirred, capsule is formed
Shell, then adds 50 grams of dispersion moisture agent sodium lauroyl glutamate and stirs, and adds the 20 grams of stirrings of avermectin B2a active compound equal
It is even, at a high speed（20000 revs/min）Shearing 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, then sequentially adds Huang
2 grams of virgin rubber, 8 grams of aluminium-magnesium silicate, 50 grams of antifreeze glycol, 1 gram of defoamer polyethers, 1 gram of preservative sodium benzoate are well mixed,
12000 revs/min carry out high speed shear 20 minutes；Then two grades of sand millings are carried out, 2% avermectin B2a micro-capsule synergy is can obtain and hangs
Floating agent is sample five.
Comparative example 3
531 grams of water, 30 grams of the microcapsule controlled-release agent carbomer of surplus are added in the reactor for have stirring, is stirred, capsule is formed
Shell, then adds 60 grams of dispersion moisture agent sodium lauroyl glutamate and stirs, and adds the 300 grams of stirrings of avermectin B2a active compound
Uniformly, at a high speed（20000 revs/min）Shearing 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, then sequentially adds
1 gram of xanthans, 5 grams of aluminium-magnesium silicate, 40 grams of antifreezing agent propane diols, 1 gram of many polysilanes of defoamer, 1 gram of preservative sodium benzoate, increasing
Imitate anhydrous fast 30 grams of the T of agent to be well mixed, 12000 revs/min carry out high speed shear 30 minutes；Then two grades of sand millings are carried out, can be obtained
It is sample six to 30% avermectin B2a micro-capsule synergy suspending agent.
Comparative example 4
287 grams of water, 50 grams of the microcapsule controlled-release agent carbomer of surplus are added in the reactor for have stirring, is stirred, capsule is formed
Shell, then adds 80 grams of dispersion moisture agent sodium lauroyl glutamate and stirs, and adds the 500 grams of stirrings of avermectin B2a active compound
Uniformly, at a high speed（20000 revs/min）Shearing 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, then sequentially adds
0.5 gram of xanthans, 0.5 gram of aluminium-magnesium silicate, 30 grams of antifreezing agent propane diols, 1 gram of defoamer n-octyl alcohol, 1 gram of preservative sodium benzoate,
50 grams of synergist fatty alcohol is well mixed, and 12000 revs/min carry out high speed shear 50 minutes；Then two grades of sand millings are carried out, can be obtained
It is sample seven to 50% avermectin B2a micro-capsule synergy suspending agent.
It should be noted that except 2%, 30%, the 50% avermectin B2a micro-capsule synergy produced in above-described embodiment 1-3
Outside suspending agent, the avermectin B2a micro-capsule synergy suspending agent of any other content in the range of 2%-50% can also be produced, is formed
New embodiment, should not be limited to situation about being enumerated in above-described embodiment.
Tensiometry Test
Surface tension size is the important indicator of preparation drug effect, the sample one configured to embodiment 1-3 and comparative example 1-4 to sample
Product seven carry out Tensiometry Test, and result of the test is as shown in table 1.
The sample one of table 1 is to the surface tension of sample seven
Table 1 shows that the avermectin B2a micro-capsule synergy suspending agent of addition isopropyl myristate synergist, which is compared, does not add synergist
Avermectin B2a micro-capsule synergy suspending agent and avermectin B2a suspending agent surface tension reduce by 19.5~23mN/m, add
Isopropyl myristate synergist hangs compared to anhydrous fast T and fatty alcohol synergist is added in reduction avermectin B2a micro-capsule synergy
Effect is more preferable in terms of floating agent surface tension.
Crop field effect experiment one：Buddhist head is penetrated in crop field insecticidal test-Hebei Jinzhou
With the avermectin B2a micro-capsule synergy suspending agent and avermectin B2a suspending agent of above-mentioned sample one to sample seven to Hebei
Jinzhou penetrates Buddhist head and carries out insecticidal test, and the drug effect of avermectin B2a micro-capsule synergy suspending agent is examined by field experiment.It is specific real
Proved recipe case is as follows：
Medication：Each sample is repeated twice；
Extension rate：2% avermectin B2a micro-capsule synergy suspending agent（Sample one）2000X, 3000X, it is other by content conversion times
Number dilution；
Use apparatus：Conventional backpack sprayer, directed spraying；
Water consumption：Every mu of 30 kg of water；
Investigation method：Using five point sampling；
Control time：Seven after medicine, 14,30,60 days；
Revision insect recluced rate（%）=（Each day residual borer population after insect population-spray before spray）Insect population before * 100/ spray；
Rectifying efficacies（%）=（Treatment region Revision insect recluced rate-check plot Revision insect recluced rate）*100/（The insect population decline of 100- check plots
Rate）.
Result of the test is shown in Table 2.
The result of 2 crop field effect experiment of table one
As known from Table 2, the avermectin B2a micro-capsule synergy suspending agent drug effect of synergist is added apparently higher than not adding synergist
Avermectin B2a micro-capsule synergy suspending agent adds synergist isopropyl myristate to the prevention effect of pear tree pear sucker
Avermectin B2a microcapsule suspending agent than adding the anhydrous fast T and synergist fatty alcohol synergist preventing and treating pear tree pear sucker of synergist
Effect is remarkably reinforced.The lasting period of avermectin B2a micro-capsule synergy suspending agent is longer 15 days than common avermectin B2a suspending agent
By 30 days, and drug effect of the avermectin B2a micro-capsule synergy suspending agent during 14 days to 30 days was preferable.
Crop field effect experiment two：Crop field insecticidal test-rice leaf roller
Rice leaf roller most pharmaceutical agents on the six directions paddy rice of Anhui generate different degrees of drug resistance.With above-mentioned sample one to
The avermectin B2a suspending agent of sample seven and avermectin B2a micro-capsule synergy suspending agent carry out insecticidal test, by crop field examine Ah
Tie up the drug effect of rhzomorph B2a micro-capsule synergy suspending agents.Specific experiment scheme is as follows：
Medication：Each sample, which is repeated twice, to be used；
Extension rate：2% avermectin B2a microcapsule suspending agent（Sample one）2000X, 3000X are other dilute by content conversion multiple
Release；
Use apparatus：Conventional backpack sprayer, directed spraying；
Water consumption：Every mu of 30 kg of water；
Investigation method：Using five point sampling；
Control time：Seven after medicine, 14,30,60 days；
Revision insect recluced rate（%）=（Each day residual borer population after insect population-spray before spray）Insect population before * 100/ spray；
Rectifying efficacies（%）=（Treatment region Revision insect recluced rate-check plot Revision insect recluced rate）*100/（The insect population decline of 100- check plots
Rate）.
Result of the test is as shown in table 3.
The result of 3 crop field effect experiment of table two
As known from Table 3, the avermectin B2a micro-capsule synergy suspending agent of synergist is added apparently higher than the AVM hereinafter for not adding synergist
Rhzomorph B2a micro-capsule synergy suspending agents add synergist isopropyl myristate to the prevention effect of paddy rice rice leaf roller
Avermectin B2a micro-capsule synergy suspending agent than adding the anhydrous fast T and synergist fatty alcohol synergist preventing and treating paddy rice rice of synergist
Leaf-roller effect is remarkably reinforced.The lasting period of avermectin B2a micro-capsule synergy suspending agent is than common avermectin B2a suspending agent
Length 15 days to 30 days, and drug effect of the avermectin B2a micro-capsule synergy suspending agent during 14 days to 30 days is preferable.
Crop field effect experiment three：Red spider on crop field insecticidal test-Jiangxi Suichuan cumquat
Crop field insecticidal test is carried out to red spider on the cumquat of Jiangxi Suichuan with same method, specific experiment scheme is as follows：
Medication：Each sample is repeated twice；
Extension rate：2% avermectin B2a microcapsule suspending agent（Sample one）2000X, 3000X are other dilute by content conversion multiple
Release；
Use apparatus：Conventional backpack sprayer, directed spraying；
Water consumption：Every mu of 30 kg of water；
Investigation method：Using five point sampling；
Control time：Seven after medicine, 14,30,60 days；
Revision insect recluced rate（%）=（Each day residual borer population after insect population-spray before spray）Insect population before * 100/ spray；
Rectifying efficacies（%）=（Treatment region Revision insect recluced rate-check plot Revision insect recluced rate）*100/（The insect population decline of 100- check plots
Rate）.
Result of the test is as shown in table 4.
The result of 4 crop field effect experiment of table three
As known from Table 4, the avermectin B2a micro-capsule synergy suspending agent of synergist is added apparently higher than the AVM hereinafter for not adding synergist
Rhzomorph B2a micro-capsule synergy suspending agents add synergist isopropyl myristate to the red spider prevention effect on cumquat
Avermectin B2a micro-capsule synergy suspending agent is than adding anhydrous fast T and synergist fatty alcohol synergist preventing and treating the planthopper effect of synergist
Fruit is remarkably reinforced.The lasting period of avermectin B2a micro-capsule synergy suspending agent arrived than long 15 days of common avermectin B2a suspending agent
30 days, the avermectin B2a micro-capsule synergy suspending agent drug effect of 14 days to 30 days was preferable.
It the above is only the preferred embodiment of the present invention, it is noted that above-mentioned preferred embodiment is not construed as pair
The limitation of the present invention.For those skilled in the art, without departing from the spirit and scope of the present invention, also
Some improvement can be made, these improvement also should be regarded as protection scope of the present invention.
Claims (3)
1. a kind of avermectin B2a micro-capsule synergy suspending agent, is made up of following component by weight percentage：Avermectin B2a
2%-50%, microcapsule controlled-release agent 0.2%-5%, dispersion moisture agent 5%-8%, thickener 0.1%-1%, preservative 0.1%, antifreezing agent 3%-
5%, defoamer 0.1%, synergist 0.2%-5%, surplus is water.
2. avermectin B2a micro-capsule synergy suspending agent according to claim 1, it is characterised in that：The microcapsule controlled-release agent
For carbomer；The dispersion moisture agent is sodium lauroyl glutamate；The thickener be the xanthans that is mixed with arbitrary proportion and
Magnesiumaluminumsilicate；The antifreezing agent is ethylene glycol or propane diols；The defoamer is multi-polysiloxane, polyethers or n-octyl alcohol；It is described
Preservative is sodium benzoate；The synergist is isopropyl myristate.
3. a kind of preparation method of the avermectin B2a micro-capsule synergy suspending agent described in claim 1 or 2, it is characterised in that its
Comprise the following steps：
（1）Water and the microcapsule controlled-release agent of amount of preparation are added in the container of stirring, is stirred, softgel shell is formed；
（2）Into above-mentioned softgel shell, add dispersion moisture agent and stir, add avermectin B2a active compound, stir, carry out
20000 revs/min of high speed shear 20 minutes, makes micro-capsule fully wrap up avermectin B2a active compound, obtains material C；
（3）Thickener, preservative, antifreezing agent, defoamer, synergist are sequentially added into above-mentioned material C, is well mixed, then enter
The high speed shear of 12000 revs/min of row 20-50 minutes, obtains material D；
（4）Above-mentioned material D is subjected to two grades of sand millings, that is, obtains avermectin B2a micro-capsule synergy suspending agent.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108353897A (en) * | 2018-03-27 | 2018-08-03 | 江苏精禾界面科技有限公司 | A kind of pesticide microcapsule suspending agent and preparation method thereof |
| CN113016815A (en) * | 2021-02-23 | 2021-06-25 | 沈阳化工大学 | Abamectin B2 microcapsule suspending agent and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101473816A (en) * | 2008-12-08 | 2009-07-08 | 吕玉成 | Avermectin microcapsule suspending agent |
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- 2017-05-26 CN CN201710383869.2A patent/CN107156150A/en not_active Withdrawn
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| CN101473816A (en) * | 2008-12-08 | 2009-07-08 | 吕玉成 | Avermectin microcapsule suspending agent |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108353897A (en) * | 2018-03-27 | 2018-08-03 | 江苏精禾界面科技有限公司 | A kind of pesticide microcapsule suspending agent and preparation method thereof |
| CN108353897B (en) * | 2018-03-27 | 2021-03-16 | 江苏精禾界面科技有限公司 | Pesticide microcapsule suspending agent and preparation method thereof |
| CN113016815A (en) * | 2021-02-23 | 2021-06-25 | 沈阳化工大学 | Abamectin B2 microcapsule suspending agent and preparation method thereof |
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