CN108353897B - Pesticide microcapsule suspending agent and preparation method thereof - Google Patents
Pesticide microcapsule suspending agent and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/26—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group; Thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
- A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
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Abstract
The invention discloses a pesticide microcapsule suspending agent and a preparation method thereof, the particle size of the pesticide microcapsule suspending agent is 0.1-20 microns, the capsule wall material adopts polyurethane or polyurea and the like, and the capsule core can be pyrethroid, organophosphorus or aniline pesticides. The invention prepares the pesticide microcapsule suspending agent by the microreactor through liquid/liquid interfacial polymerization, has simple process, controllable and evenly distributed grain diameter of the prepared microcapsule, simplifies the preparation process of the pesticide microcapsule suspending agent, reduces the production amplification effect, and has important value in the aspect of pesticide microencapsulation.
Description
Technical Field
The invention relates to the technical field of chemical industry, in particular to a pesticide microcapsule suspending agent and a preparation method thereof.
Background
The pesticide makes great contribution to agricultural production increase and farmer income increase, but the conventional pesticide formulations such as missible oil, powder, wettable powder, oil and the like gradually show the defects of high toxicity, high residue, poor environmental compatibility and the like. In recent years, as people's awareness of environmental protection is continuously enhanced, a pesticide microcapsule suspension which uses a high molecular material as a capsule wall or a capsule membrane and wraps pesticide active substances through a chemical, physical or physicochemical method to form a semipermeable capsule membrane is gradually accepted by people. Compared with the traditional pesticide, the pesticide microcapsule suspending agent can reduce the toxicity, phytotoxicity and environmental pollution of the pesticide, and has the advantages of long lasting time, low toxicity to the environment and human bodies, good stability of active ingredients, difficult rain wash and the like.
Although the pesticide microcapsule suspending agent has achieved certain achievements in research and application, a plurality of problems still exist, mainly including complex processing technology, higher production cost, great technical difficulty and certain investment risk. The patent with publication number CN101305725B discloses a chlorpyrifos and pymetrozine compound microcapsule suspending agent and a preparation method thereof, wherein an in-situ polymerization method is adopted, namely, monomers such as formaldehyde and urea or melamine are prepolymerized in a weak alkali environment, the acidic condition is adjusted to ensure that prepolymer molecules are continuously crosslinked, and insoluble resin capsule shells are formed on the surfaces of core materials by deposition. The patent with publication number CN103734162B discloses a pyraclostrobin microcapsule suspending agent, which adopts an interfacial polymerization method, i.e. a chain extender is added to cause an oil-soluble monomer and a water-soluble monomer to perform a polycondensation reaction at an oil-water interface to generate a capsule shell with certain hardness, and an active substance is coated.
Therefore, the problem to be solved by the technical personnel in the field is how to provide a stable and easily controlled method for preparing the pesticide microcapsule suspending agent, and the prepared pesticide microcapsule suspending agent has good stability and permeability.
Disclosure of Invention
In view of the above, the invention provides a pesticide microcapsule suspending agent, which comprises the following components in percentage by weight:
1 to 50 percent of active ingredient, 2 to 10 percent of capsule wall material, 1 to 10 percent of dispersant, 0 to 2 percent of defoamer, 0.2 to 4 percent of synergist, 0 to 5 percent of preservative and the balance of water.
The beneficial effects of the above technical scheme are: provides a pesticide microcapsule suspending agent formula which has stable preparation performance and uniform slow release function.
Preferably, the active ingredient is any one or a mixture of more of cypermethrin, fenvalerate, fenpropathrin, lambda-cyhalothrin, deltamethrin, bifenthrin, chlorpyrifos, phoxim, pirimiphos-methyl, alachlor, acetochlor and pretilachlor.
Preferably, the capsule wall material is one or a mixture of polyurethane or polyurea.
Further, the capsule wall material is obtained by the polycondensation reaction of a reaction monomer A and a reaction monomer B, wherein the reaction monomer A comprises one or more of diphenylmethane diisocyanate, toluene diisocyanate, isophorone diisocyanate, dicyclohexylmethane diisocyanate or hexamethylene diisocyanate; the reaction monomer B comprises one or more of ethylenediamine, hexamethylenediamine, diethylenetriamine, triethylene tetramine, ethylene glycol, propylene glycol or polyethylene glycol; the weight ratio of the reaction monomer A to the reaction monomer B is 1: 0.1-0.5.
Preferably, the dispersing agent is any one or a mixture of more of lignosulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate, macromolecular carboxylate, modified naphthalenesulfonate, alkylphenol polyoxyethylene ether and EO/PO block polyether.
Preferably, the defoaming agent is an organic silicon defoaming agent and/or a polyether defoaming agent; the synergist is any one or a mixture of organic silicon, rosin-based vegetable oil and palm kernel oil fatty acid methyl ester; the preservative is any one or a mixture of more of benzoic acid, sodium benzoate, sorbic acid, potassium sorbate and sulfite.
The beneficial effects of the above technical scheme are: when the pesticide microcapsule suspension is produced and used specifically, the pesticide type and the capsule wall material can be selected according to actual requirements, and the auxiliary agent can be selected according to the selected pesticide type, the capsule wall material type and the actual requirements, so that the reaction is more sufficient, and the prepared pesticide microcapsule suspension has the best performance.
The invention also aims to provide a preparation method of the pesticide microcapsule suspending agent, the method has small equipment volume and simple process, can obtain various pesticide microcapsule suspending agent products by adjusting the process parameters of a micro-reaction device, has uniform and controllable particle size, and can prepare various pesticide microcapsule suspending agents with good safety, high stability and slow release performance by optimizing the content of effective components and the types of auxiliary agents, and the method specifically comprises the following steps:
1) mixing and dissolving the effective components and the reaction monomer A to prepare a dispersed phase;
2) adding a dispersing agent, a defoaming agent and a reaction monomer B into water, and uniformly stirring to prepare a continuous phase;
3) adjusting the injection rates of a micro-reactor channel and a push injection pump in the micro-reactor channel, and then simultaneously injecting the dispersed phase prepared in the step 1) and the continuous phase prepared in the step 2) into the micro-reactor channel by using the push injection pump for reaction;
preferably, the reaction temperature in the microreactor channel in the step 3) is 40-60 ℃, and the reaction time is 1-60 min.
The beneficial effects of the above technical scheme are: the reaction has high reaction rate by controlling reasonable reaction temperature.
Further, the microreactor used in the step 3) comprises a heat exchange layer; the heat exchange layer is an electric heating layer, a heat radiation belt or a microwave heating layer.
The beneficial effects of the above technical scheme are: whether heating is carried out or not can be selected according to actual production requirements.
Preferably, the microreactor channel is a metal channel, a ceramic channel or an engineering plastic channel.
The beneficial effects of the above technical scheme are: when the microcapsule preparation reaction is carried out, the pesticide raw materials and the auxiliary agent raw materials are prevented from corroding the channel of the microreactor, the purity and the beneficial effect of the pesticide product are ensured, and the service life of the microreactor is ensured.
The invention also aims to provide application of the method for preparing the pesticide microcapsule suspending agent, which is applied to continuous production of the pesticide microcapsule suspending agent, and particularly relates to that the inlet ends of raw materials of a plurality of microreactors are sequentially connected in series, the outlet ends of products are sequentially connected in series to form a continuous micro-reaction system, so that the small-scale process can be directly amplified without difference, the characteristic size of the microchannel is increased instead of the characteristic size of the microchannel, and the method can be used for directly amplifying production without any change and has high application value.
By combining the technical scheme, the invention has the beneficial effects that:
(1) the pesticide microcapsule suspending agent is continuously prepared by the microreactor, the process is simple, the particle size of the microcapsule is controllable, and the particle size distribution is uniform;
(2) the volume of the microreactor used in the invention is reduced, and the microreactor is only 1/100 or even 1/1000 of the traditional batch reaction kettle;
(3) the continuous micro-reactor system adopted by the invention has high mass and heat transfer efficiency, can better control the reaction temperature, shorten the retention time, change the intensity of chemical reaction, effectively avoid side reaction and enable the chemical reaction rate to approach the kinetic limit;
(4) the continuous preparation method adopted by the invention has safer reaction process, is different from the traditional batch reaction kettle, and the microreactor is a continuous flow reaction, so that the quantity of chemicals staying in the reactor is always small, the intrinsic safety can be realized, and the microreactor is closed, so that the harm caused by toxic materials can be avoided;
(5) the micro-reactor used in the continuous preparation method has high mixing efficiency, and the micro-channel is designed to carry out overlap intensified mixing on the fluid or carry out mixing by using jet flow collision, so that emulsion can be formed with little or no emulsifier;
(6) the micro-reactor used in the continuous preparation method has high mixing efficiency, and the micro-channel is designed to perform overlap intensified mixing on the fluid or perform mixing by jet flow collision, so that an emulsion can be formed without using an emulsifier, and the preparation cost is effectively reduced.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The 20% bifenthrin microcapsule is prepared by the following steps
1) Preparation of dispersed phase: uniformly mixing 20% of bifenthrin, 4% of diphenylmethane diisocyanate and 5% of calcium dodecyl benzene sulfonate;
2) preparation of continuous phase: 4% of lignosulfonate, 1% of ethylenediamine, 5% of organic silicon defoamer and 40% of water are uniformly stirred;
3) and (3) forming of the microcapsule: respectively filling the dispersed phase and the continuous phase into a stirring kettle, wherein the dispersed phase and the continuous phase are matched with the same push-injection pump, the dispersed phase stirring kettle is pushed at the speed of 100mL/min, the continuous phase stirring kettle is pushed at the speed of 200ul/min, the dispersed phase solution and the continuous phase solution form microcapsules in a micro-reactor channel, and the particle size of the microcapsules is between 1 and 2 microns;
4) curing of the microcapsules: controlling the temperature of the micro-reactor channel at 40 ℃, controlling the discharging speed, and enabling the micro-capsule to react for 1 hour in the waveform micro-reactor channel to form a stable micro-capsule structure;
5) preparation of microcapsule suspension: adding 1% preservative, 2% synergist and water to make up to 100%, and stirring uniformly.
In order to optimize the scheme, according to production and use requirements, the effective components of the pesticide can also be one or a mixture of more of cypermethrin, fenvalerate, fenpropathrin, lambda-cyhalothrin, deltamethrin, chlorpyrifos, phoxim, pirimiphos-methyl, alachlor, acetochlor and pretilachlor;
in order to optimize the technical scheme, the diphenylmethane diisocyanate can be replaced by one or more of toluene diisocyanate, isophorone diisocyanate, dicyclohexylmethane diisocyanate or hexamethylene diisocyanate; the ethylenediamine can be replaced by one or more of hexamethylenediamine, diethylenetriamine, triethylene tetramine, ethylene glycol, propylene glycol or polyethylene glycol;
in order to optimize the scheme, the dispersing agent can also be one or a mixture of more of alkylphenol polyoxyethylene formaldehyde condensate, macromolecular carboxylate, modified naphthalene sulfonate, alkylphenol polyoxyethylene and EO/PO block polyether;
in order to optimize the scheme, the defoaming agent can also be selected to be a polyether defoaming agent.
Example 2
The 30% pirimiphos-methyl microcapsule is prepared by the following steps
1) Preparation of dispersed phase: uniformly mixing 30% of pirimiphos-methyl, 4% of diphenylmethane diisocyanate and 3% of styrylphenol polyoxyethylene ether;
2) preparation of continuous phase: 4 percent of alkylphenol polyoxyethylene ether, 1 percent of ethylenediamine, 0.5 percent of organic silicon defoamer and 20 percent of water are evenly stirred;
3) and (3) forming of the microcapsule: respectively filling the dispersed phase and the continuous phase into stirring kettles, wherein the dispersed phase and the continuous phase are matched with the same push-injection pump, the two stirring kettles are both pushed at the speed of 100ul/min, the dispersed phase solution and the continuous phase solution form microcapsules in a micro-reactor channel, and the particle size of the microcapsules can be between 5 and 6 micrometers;
4) curing of the microcapsules: controlling the temperature of the micro-reactor channel at 50 ℃, controlling the discharging speed, and enabling the micro-capsule to react in the waveform micro-reactor channel for 30 minutes to form a stable micro-capsule structure;
5) preparing microcapsules: adding 1% preservative, 2% synergist and water to make up to 100%, and stirring uniformly.
In order to optimize the scheme, according to the actual production and use requirements, the effective components of the pesticide can also be one or a mixture of more of cypermethrin, fenvalerate, fenpropathrin, lambda-cyhalothrin, deltamethrin, bifenthrin, chlorpyrifos, phoxim, pendimethalin and acetochlor;
in order to optimize the technical scheme, the diphenylmethane diisocyanate can be replaced by one or more of toluene diisocyanate, isophorone diisocyanate, dicyclohexylmethane diisocyanate or hexamethylene diisocyanate; the ethylenediamine can be replaced by one or more of hexamethylenediamine, diethylenetriamine, triethylene tetramine, ethylene glycol, propylene glycol or polyethylene glycol;
in order to optimize the scheme, the dispersing agent can also be selected from one or a mixture of more of lignosulfonate, alkylphenol polyoxyethylene formaldehyde condensate, macromolecular carboxylate, modified naphthalenesulfonate and EO/PO block polyether;
in order to optimize the scheme, the defoaming agent can also be selected to be a polyether defoaming agent.
Example 3
The 50% acetochlor microcapsule preparation method comprises the following steps
1) Preparation of dispersed phase: mixing 50% of acetochlor, 4% of diphenylmethane diisocyanate and 3% of fatty alcohol-polyoxyethylene ether uniformly;
2) preparation of continuous phase: 4% of modified naphthalene sulfonate, 1% of ethylenediamine, 1% of polyether defoamer and 20% of water are uniformly stirred;
3) and (3) forming of the microcapsule: respectively filling the dispersed phase and the continuous phase into a stirring kettle, wherein the dispersed phase and the continuous phase are matched with the same push-injection pump, the dispersed phase stirring kettle is pushed at the speed of 200ul/min, the continuous phase stirring kettle is pushed at the speed of 130ul/min, the dispersed phase and the continuous phase solution form microcapsules in a micro-reactor channel, and the particle size of the microcapsules can be 3-4 microns;
4) curing of the microcapsules: controlling the temperature of the micro-reactor channel at 60 ℃, controlling the discharging speed, and enabling the micro-capsule to react in the waveform micro-reactor channel for 20 minutes to form a stable micro-capsule structure;
5) preparing microcapsules: adding 1% antiseptic, 1% synergist, and water to make up to 100%, and stirring.
In order to optimize the scheme, according to actual production and use requirements, the pesticide active ingredient can also be one or a mixture of more of cypermethrin, fenvalerate, fenpropathrin, lambda-cyhalothrin, deltamethrin, bifenthrin, chlorpyrifos, phoxim, pendimethalin and pirimiphos-methyl;
in order to optimize the technical scheme, the diphenylmethane diisocyanate can be replaced by one or more of toluene diisocyanate, isophorone diisocyanate, dicyclohexylmethane diisocyanate or hexamethylene diisocyanate; the ethylenediamine can be replaced by one or more of hexamethylenediamine, diethylenetriamine, triethylene tetramine, ethylene glycol, propylene glycol or polyethylene glycol;
in order to optimize the scheme, the dispersing agent can also be selected from one or a mixture of more of lignosulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate, alkylphenol polyoxyethylene ether, macromolecular carboxylate and EO/PO block polyether;
in order to optimize the scheme, the defoaming agent can also be selected to be a polyether defoaming agent.
Comparative example 1
Preparation of 20% bifenthrin microcapsule suspending agent by traditional intermittent interfacial polymerization method
(1) Respectively weighing 20g of bifenthrin, 5g of toluene diisocyanate, 5g of calcium dodecyl benzene sulfonate, 4g of lignosulfonate, 2g of ethylenediamine, 2g of an organic silicon defoamer, 5g of polycarboxylate, 1g of sodium benzoate and 2g of a synergist, and weighing for later use;
(2) preparation of the dispersed phase: uniformly mixing the weighed bifenthrin and hexamethylene diisocyanate, and heating and melting at 50 ℃;
(3) preparation of the continuous phase: mixing and stirring the weighed calcium dodecyl benzene sulfonate, lignosulfonate, organic silicon defoamer, polycarboxylate and water uniformly at the temperature of 50 ℃ to prepare a continuous phase;
(4) preparing the microcapsule: keeping the temperature of the equipment at 50 deg.C, mixing the dispersed phase and continuous phase, and shearing and emulsifying at 5000rpm for 3min (particle diameter D)90Controlling the particle size to be 1-3 microns) to obtain an oil-in-water emulsion; adding the weighed ethylenediamine in batches within 30 minutes under the stirring condition, and continuously curing for 5 hours at the temperature of 50 ℃ to ensure that the capsule wall is completely reacted;
(5) preparing a microcapsule: adding the weighed sodium benzoate, glycerol and magnesium aluminum silicate into the mixture, adding 100g of water to the mixture, and uniformly stirring the mixture to obtain a microcapsule suspending agent;
(6) equipment cleaning: after the reaction is finished, the reaction kettle, shearing, stirring and other equipment are cleaned in time, and if necessary, the reaction kettle is soaked and washed by a polar solvent.
And (3) effect comparison:
the materials of the example 1 and the comparative example 1 are the same, the process is different, the bifenthrin microcapsule suspending agent obtained in the two examples is detected, and the detection result is as follows:
and (4) analyzing results: as can be seen from the above table, the stability test results are better in example 1 compared to comparative example 1, especially the effect is better when a freeze-thaw experiment is performed. Mainly, in the technical scheme disclosed by the invention, the reaction is uniform, the side reaction is less, the encapsulation rate is high, and the quality is more stable; comparative example 1 adopts batch reactor technology, and some side reactions in the stability experiment of the product package later stage can continue to change, influence product stability. Therefore, the bifenthrin microcapsule suspending agent prepared by the invention has excellent storage stability and good practical value through formula optimization and process improvement.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (6)
1. A preparation method of a pesticide microcapsule suspending agent is characterized by comprising the following steps:
1) the pesticide microcapsule suspending agent comprises the following components in percentage by weight:
1-50% of active ingredients, 2-10% of capsule wall materials, 1-10% of dispersing agents, 0-2% of defoaming agents, 0.2-4% of synergists, 0-5% of preservatives and the balance of water; the capsule wall material is one or a mixture of polyurethane or polyurea; the capsule wall material is obtained by the polycondensation reaction of a reaction monomer A and a reaction monomer B, wherein the reaction monomer A is selected from one or more of diphenylmethane diisocyanate, toluene diisocyanate, isophorone diisocyanate, dicyclohexylmethane diisocyanate or hexamethylene diisocyanate; the reaction monomer B is selected from one or more of ethylenediamine, hexamethylenediamine, diethylenetriamine, triethylene tetramine, ethylene glycol, propylene glycol or polyethylene glycol; the weight ratio of the reaction monomer A to the reaction monomer B is 1:0.1-0.5, firstly, the effective components and the reaction monomer A are mixed and dissolved to prepare a dispersed phase;
2) adding a dispersing agent, a defoaming agent and a reaction monomer B into water, and uniformly stirring to prepare a continuous phase;
3) adjusting the injection rate of a push injection pump in the microreactor, and then simultaneously injecting the dispersed phase prepared in the step 1) and the continuous phase prepared in the step 2) into a channel of the microreactor by using the push injection pump to react to obtain a pesticide microcapsule suspending agent;
the active ingredient is one of bifenthrin, pirimiphos-methyl or acetochlor.
2. The method for preparing a pesticide microcapsule suspension as claimed in claim 1, wherein the dispersant is any one or a mixture of several of lignosulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate, polycarboxylate, modified naphthalenesulfonate, alkylphenol polyoxyethylene ether and EO/PO block polyether.
3. The method for preparing a suspension of pesticide microcapsules according to claim 1, wherein the reaction temperature in the microreactor channel in the step 3) is 40-60 ℃ and the reaction time is 1-60 min.
4. The method for preparing a suspension of pesticide microcapsules according to claim 1, wherein the microreactor used in the step 3) comprises a heat exchange layer; the heat exchange layer is an electric heating layer, a heat radiation belt or a microwave heating layer.
5. The method for preparing a suspension of pesticide microcapsules according to claim 1, wherein the microreactor channel is a metal channel, a ceramic channel or an engineering plastic channel.
6. The application of the preparation method of the pesticide microcapsule suspending agent according to claim 1 is characterized in that the preparation method is applied to the continuous production of the pesticide microcapsule suspending agent, and specifically, the raw material inlet ends of a plurality of microreactors are connected in series in sequence, and the product outlet ends are connected in series in sequence to form a continuous micro-reaction system.
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| CN109717187A (en) * | 2018-12-21 | 2019-05-07 | 江苏艾津农化有限责任公司 | A kind of chloroacetanilide herbicides microcapsule suspending agent and preparation method thereof |
| CN109452272A (en) * | 2018-12-21 | 2019-03-12 | 江苏艾津农化有限责任公司 | A kind of avermectin microcapsule agent and preparation method thereof |
| CN109699642A (en) * | 2018-12-21 | 2019-05-03 | 江苏精禾界面科技有限公司 | A kind of pesticide micro-capsule and preparation method thereof can easily be accommodated rate of release |
| CN109757475A (en) * | 2019-03-01 | 2019-05-17 | 杨卫东 | A kind of microcapsule formulation and preparation method thereof coating solid pesticide raw medicine |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2008238146A (en) * | 2007-03-29 | 2008-10-09 | Okayama Prefecture Industrial Promotion Foundation | Microreactor |
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