CN107126557A - 抗肺炎链球菌的疫苗和组合物 - Google Patents

抗肺炎链球菌的疫苗和组合物 Download PDF

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Publication number
CN107126557A
CN107126557A CN201710169055.9A CN201710169055A CN107126557A CN 107126557 A CN107126557 A CN 107126557A CN 201710169055 A CN201710169055 A CN 201710169055A CN 107126557 A CN107126557 A CN 107126557A
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CN
China
Prior art keywords
seq
lys
ala
asp
glu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710169055.9A
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English (en)
Chinese (zh)
Inventor
T·吉瑞
R·玛丽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Childrens Hospital
Genocea Biosciences Inc
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Boston Childrens Hospital
Genocea Biosciences Inc
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Filing date
Publication date
Application filed by Boston Childrens Hospital, Genocea Biosciences Inc filed Critical Boston Childrens Hospital
Publication of CN107126557A publication Critical patent/CN107126557A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CN201710169055.9A 2009-06-29 2010-06-29 抗肺炎链球菌的疫苗和组合物 Pending CN107126557A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US22154109P 2009-06-29 2009-06-29
US61/221,541 2009-06-29
US24061609P 2009-09-08 2009-09-08
US24059809P 2009-09-08 2009-09-08
US61/240,598 2009-09-08
US61/240,616 2009-09-08
US31626710P 2010-03-22 2010-03-22
US61/316,267 2010-03-22
CN2010800388746A CN102548572A (zh) 2009-06-29 2010-06-29 抗肺炎链球菌的疫苗和组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2010800388746A Division CN102548572A (zh) 2009-06-29 2010-06-29 抗肺炎链球菌的疫苗和组合物

Publications (1)

Publication Number Publication Date
CN107126557A true CN107126557A (zh) 2017-09-05

Family

ID=43449681

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2010800388746A Pending CN102548572A (zh) 2009-06-29 2010-06-29 抗肺炎链球菌的疫苗和组合物
CN201710169055.9A Pending CN107126557A (zh) 2009-06-29 2010-06-29 抗肺炎链球菌的疫苗和组合物

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CN2010800388746A Pending CN102548572A (zh) 2009-06-29 2010-06-29 抗肺炎链球菌的疫苗和组合物

Country Status (15)

Country Link
US (2) US10105412B2 (enExample)
EP (1) EP2448592B1 (enExample)
JP (1) JP5931724B2 (enExample)
KR (1) KR101748453B1 (enExample)
CN (2) CN102548572A (enExample)
AU (1) AU2010273708B2 (enExample)
BR (1) BRPI1011919A2 (enExample)
CA (1) CA2803061A1 (enExample)
IL (1) IL217166A0 (enExample)
IN (1) IN2012DN00791A (enExample)
MX (1) MX2012000158A (enExample)
NZ (1) NZ597858A (enExample)
RU (1) RU2580299C2 (enExample)
SG (2) SG10201403702SA (enExample)
WO (1) WO2011008548A1 (enExample)

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WO2014018904A1 (en) * 2012-07-26 2014-01-30 Genocea Biosciences, Inc. Fused antigen vaccines and compositions against streptococcus pneumoniae
ES2959258T3 (es) 2013-02-07 2024-02-22 Childrens Medical Center Antígenos proteicos que proporcionan protección contra la colonización y/o la enfermedad neumocócicas
US20150079132A1 (en) * 2013-09-17 2015-03-19 Path Evoking protection against streptotoccus pneumoniae incorporating b-cell and t-cell pneumococcal protein antigens and pneumococcal polysaccharides delivered concomitantly
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JP7535791B2 (ja) 2018-09-12 2024-08-19 ザ チルドレンズ メディカル センター コーポレーション 肺炎球菌融合タンパク質ワクチン
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RU2728938C1 (ru) * 2020-05-06 2020-08-03 Федеральное государственное бюджетное учреждение науки "Научный центр биомедицинских технологий Федерального медико-биологического агентства" (ФГБУН НЦБМТ ФМБА России) Применение даларгина для производства лекарственных средств профилактики пневмонии
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KR20240099160A (ko) 2021-09-09 2024-06-28 아피니백스, 인크. 다가 폐렴구균 백신

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Also Published As

Publication number Publication date
KR20120093141A (ko) 2012-08-22
US11207375B2 (en) 2021-12-28
MX2012000158A (es) 2012-06-08
CA2803061A1 (en) 2011-01-20
EP2448592A4 (en) 2013-04-24
RU2011153032A (ru) 2013-08-10
IN2012DN00791A (enExample) 2015-06-26
US10105412B2 (en) 2018-10-23
JP5931724B2 (ja) 2016-06-08
SG177402A1 (en) 2012-02-28
IL217166A0 (en) 2012-02-29
AU2010273708A8 (en) 2012-06-14
CN102548572A (zh) 2012-07-04
RU2580299C2 (ru) 2016-04-10
KR101748453B1 (ko) 2017-06-16
AU2010273708A1 (en) 2012-02-23
WO2011008548A8 (en) 2012-03-08
SG10201403702SA (en) 2014-09-26
US20190298795A1 (en) 2019-10-03
NZ597858A (en) 2014-01-31
US20110020386A1 (en) 2011-01-27
WO2011008548A1 (en) 2011-01-20
JP2012532134A (ja) 2012-12-13
BRPI1011919A2 (pt) 2017-09-26
EP2448592A1 (en) 2012-05-09
EP2448592B1 (en) 2020-06-17
AU2010273708B2 (en) 2015-10-01

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