CN107126231B - Internal deep layer major-middle artery local pulse wave velocity detection probe - Google Patents

Internal deep layer major-middle artery local pulse wave velocity detection probe Download PDF

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CN107126231B
CN107126231B CN201710468471.9A CN201710468471A CN107126231B CN 107126231 B CN107126231 B CN 107126231B CN 201710468471 A CN201710468471 A CN 201710468471A CN 107126231 B CN107126231 B CN 107126231B
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electrode
sound transmission
signal wire
ultrasonic
transmission surface
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CN107126231A (en
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张榆锋
韩素雅
高莲
章克信
陈建华
王玉茜
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Yunnan University YNU
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/02Measuring pulse or heart rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A61B5/282Holders for multiple electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

The invention relates to a probe for detecting the local pulse wave velocity of deep aorta and middle artery in a body, belonging to the field of biomedical engineering detection. This wave speed detection probe includes: the ultrasonic sound transmission device comprises a probe shell (1) with a supporting and protecting effect, a rectangular sound transmission surface (5) arranged at the top of the probe shell (1), an ultrasonic transducer linear array (7) arranged at the center of the rectangular sound transmission surface (5), a first electrode (4), a second electrode (6), a third electrode (8) and a fourth electrode (9) arranged at the middle points of four sides of the rectangular sound transmission surface (5), a damping backing (2) packaged at the back of the rectangular sound transmission surface (5), an electrode signal wire (3) and an ultrasonic signal wire (10) for transmitting signals, and an electrode signal cable (12) and an ultrasonic signal cable (11) which are respectively connected with the electrode signal wire (3) and the ultrasonic signal wire (10); the invention has the advantages that: simple structure, simple operation, small measurement error of the wave velocity of the local pulse wave and high precision.

Description

Internal deep layer major-middle artery local pulse wave velocity detection probe
Technical Field
The invention relates to a probe for detecting the local pulse wave velocity of deep aorta and middle artery in a body, belonging to the field of biomedical engineering detection.
Background
Cardiovascular and cerebrovascular diseases caused by arteriosclerotic diseases, such as coronary heart disease, cerebral apoplexy and the like, become a main cause of death of human beings due to diseases all over the world. Research shows that the pulse wave velocity is directly related to the arteriosclerosis degree, and the increase of the arteriosclerosis degree leads to the increase of the pulse wave velocity, so that the pulse wave velocity is an independent prediction factor of the cardiovascular and cerebrovascular diseases. The accurate measurement of the pulse wave velocity has important significance for the early diagnosis of arteriosclerosis diseases and cardiovascular and cerebrovascular diseases caused by the arteriosclerosis diseases.
At present, coronary artery imaging is mainly used for image examination and diagnosis of deep aorta and middle artery lesions of human bodies such as coronary artery. The disadvantages of such methods are: the equipment is expensive and the operation is complex. Early understanding and diagnosis of the extent of coronary lesions by non-invasive methods has become a focus of research. The method for diagnosing the occurrence and development of deep-layer large and medium arteriosclerotic lesions of human bodies such as coronary artery and the like by measuring the wave velocity of local pulse waves is a direct non-invasive method. The existing measurement of the local pulse wave velocity of the coronary artery mainly comprises the steps of scanning the pulse wave propagation time at a certain section of specific distance of the coronary artery through high-frame-frequency ultrasound, and dividing the propagation time by a fixed distance to obtain the local pulse wave velocity. However, the detection of the propagated pulse wave is greatly influenced by external interference, and the reference time between waveforms is difficult to accurately determine, so that a large error is generated in the estimation of the wave velocity of the pulse wave. The invention provides a probe for detecting the local pulse wave velocity of the major and middle arteries in the deep layer of a human body, and aims to avoid mutual interference among pulse waves in the measurement process and improve the accuracy of reference time.
Through literature search, the public report same as the technology of the invention is not found.
Disclosure of Invention
The invention aims to overcome the defects of the existing pulse wave detection method, avoid the mutual interference among pulse wave shapes in the measurement process and improve the accuracy of reference time, thereby providing the probe for detecting the local pulse wave velocity of the large and medium arteries in the deep layer of the body.
The invention relates to a probe for detecting the local pulse wave velocity of the deep major and middle arteries in the body, which comprises: the ultrasonic sound transmission device comprises a probe shell (1) with a supporting and protecting effect, a rectangular sound transmission surface (5) arranged at the top of the probe shell (1), an ultrasonic transducer linear array (7) arranged at the center of the rectangular sound transmission surface (5), a first electrode (4), a second electrode (6), a third electrode (8) and a fourth electrode (9) arranged at the middle points of four sides of the rectangular sound transmission surface (5), a damping backing (2) packaged at the back of the rectangular sound transmission surface (5), an electrode signal wire (3) and an ultrasonic signal wire (10) for transmitting signals, and an electrode signal cable (12) and an ultrasonic signal cable (11) which are respectively connected with the electrode signal wire (3) and the ultrasonic signal wire (10); the distance between the first electrode (4) and the third electrode (8) which are arranged at the middle points of the two short sides of the rectangular sound-transmitting surface (5) is not less than 30mm, and the distance between the second electrode (6) and the fourth electrode (9) which are arranged at the middle points of the two long sides is not less than 10 mm.
The ultrasonic and electrode detection and measurement used in the invention are public technologies; the used devices such as electrodes, ultrasonic arrays, matching layers, damping backings, signal lines and the like are all purchased in the market.
The invention has the advantages that: simple structure, simple operation, small measurement error of the wave velocity of the local pulse wave and high precision. The human body spontaneous electrocardiosignal is uniformly used as the initial time reference, so that the mutual interference among pulse waveforms in the measurement process is avoided, the estimation precision of the pulse wave transmission delay time is improved, and the accuracy of the local pulse wave velocity detection of the large and medium arteries in the deep layer in the body is effectively improved.
Description of the drawings:
FIG. 1 is a schematic view of the structure of the present invention.
FIG. 2 is a schematic diagram of an embodiment of the present invention.
The specific implementation mode is as follows:
the present invention will be described in further detail with reference to the accompanying drawings. The ultrasonic and electrode detection and measurement used by the invention are public technologies.
As shown in fig. 1, the probe for detecting the local pulse wave velocity of the deep aorta and the middle aorta in the body of the invention comprises: the ultrasonic probe comprises a probe shell 1 playing a role in supporting and protecting, a rectangular sound transmission surface 5 arranged at the top of the probe shell 1, an ultrasonic transducer linear array 7 arranged at the center of the rectangular sound transmission surface 5, a first electrode 4, a second electrode 6, a third electrode 8 and a fourth electrode 9 arranged at the middle points of four sides of the rectangular sound transmission surface 5, a damping backing 2 arranged at the back of the rectangular sound transmission surface 5 in a packaging manner, an electrode signal wire 3 and an ultrasonic signal wire 10 for transmitting signals, and an electrode signal cable 12 and an ultrasonic signal cable 11 which are respectively connected with the electrode signal wire 3 and the ultrasonic signal wire 10; the distance between the first electrode 4 and the third electrode 8 which are arranged at the middle points of two short sides of the rectangular sound-transmitting surface 5 is not less than 30mm, and the distance between the second electrode 6 and the fourth electrode 9 which are arranged at the middle points of two long sides is not less than 10 mm.
Taking the aortic arch pulse wave velocity detection as an example, the detection processing process is as follows: first, the subject takes a supine position, and the chest is exposed by removing the upper garment. A detection operator takes a medical ultrasonic couplant to be smeared on the chest skin corresponding to the heart aortic arch of a detection object; the ultrasonic probe is started, and the sound beam for adjusting the detection position and direction of the probe passes through the rib clearance to reach the heart aortic arch, as shown in fig. 2. Meanwhile, the first electrode 4, the second electrode 6, the third electrode 8 and the fourth electrode 9 receive the self-generated electrocardiosignals of the human body, send the self-generated electrocardiosignals to the signal amplification and filtering module for corresponding processing, and then obtain two groups of independent electrocardiosignal waveforms through arithmetic superposition operation. And sending the received ultrasonic radio frequency echo signal to ultrasonic imaging processing, and extracting a pulse displacement sequence wave transmitted by the aortic arch section. And determining the time reference point of the serial pulse displacement waves by the electrocardio start, and calculating the pulse wave delay time. And finally, calculating the wave velocity of the local pulse wave of the aortic arch according to the detection distance, and averaging the wave velocities of the pulse waves measured at intervals of a period of time to obtain the final detection result.

Claims (1)

1. A probe for detecting the wave velocity of local pulse waves of deep aorta and middle aorta in a body is characterized by comprising: the ultrasonic sound transmission device comprises a probe shell (1) with a supporting and protecting effect, a rectangular sound transmission surface (5) arranged at the top of the probe shell (1), an ultrasonic transducer linear array (7) arranged at the center of the rectangular sound transmission surface (5), a first electrode (4), a second electrode (6), a third electrode (8) and a fourth electrode (9) arranged at the middle points of four sides of the rectangular sound transmission surface (5), a damping backing (2) packaged at the back of the rectangular sound transmission surface (5), an electrode signal wire (3) and an ultrasonic signal wire (10) for transmitting signals, and an electrode signal cable (12) and an ultrasonic signal cable (11) which are respectively connected with the electrode signal wire (3) and the ultrasonic signal wire (10); wherein, the distance between the first electrode (4) and the third electrode (8) which are arranged at the middle points of the two short sides of the rectangular sound-transmitting surface (5) is not less than 30mm, and the distance between the second electrode (6) and the fourth electrode (9) which are arranged at the middle points of the two long sides is not less than 10 mm; the first electrode (4), the second electrode (6), the third electrode (8) and the fourth electrode (9) receive electrocardiosignals of a human body from the self, transmit the electrocardiosignals to the electrode signal wire (3), transmit the electrocardiosignals to the signal amplifying and filtering module through the electrode signal cable (12) connected with the electrode signal wire (3) to amplify and filter the electrocardiosignals, and then perform arithmetic superposition operation on the amplified and filtered electrocardiosignals to obtain two groups of independent electrocardiosignal waveforms.
CN201710468471.9A 2017-06-20 2017-06-20 Internal deep layer major-middle artery local pulse wave velocity detection probe Active CN107126231B (en)

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CN102805621B (en) * 2012-07-26 2014-03-26 中国科学院电工研究所 Magnetic, acoustic and electric imaging system and imaging method
JP6299509B2 (en) * 2014-07-31 2018-03-28 セイコーエプソン株式会社 Ultrasonic device and probe, electronic apparatus and ultrasonic imaging apparatus
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