A kind of livestock and poultry cultivation air modifying agent is being prepared for preventing and treating porcine respiratory disease
Application in the drug of disease
Technical field
The present invention relates to livestock and poultry cultivation fields, and in particular to a kind of livestock and poultry cultivation air modifying agent and preparation method and its should
With.
Background technology
Livestock and poultry breeding industry refers to the animal tamed using livestock and poultry etc. by the mankind, by artificial feeding, breeding, makes it will
The plants such as herbage and feed can be changed into animal energy, to obtain the animal products such as fowl, poultry meat product, egg, milk, wool, cashmere
Production division.Livestock and poultry breeding industry is the important component of agricultural.In recent years, China's animal husbandry development is swift and violent, large-scale cultivation
Family and cultivation Specialty Co-operative Organization increase year by year, and the thing followed is Livestock pollution problem.Breeding pollution is primarily referred to as, animal excretion
Object collect difficult, animals died of illness harmless treatment be not thorough and breeding production in set up article etc. surrounding enviroment influenced, packet
Include pollution of waterhead, soil pollution and air pollution etc..Especially air pollution not only influences surrounding enviroment, but also seriously affects
Livestock and poultry breeding industry causes breathing problem of cultivation livestock and poultry etc..For example, in pig breeding industry, bad air pole easily leads to porcine respiratory
Disease.One of the problem of porcine respiratory disease is puzzlement modernized pig raising industry most serious, it in addition to cause pig directly dead with
Outside, treatment cost is also added, feed conversion rate is reduced, causes pig slow-growing, anorexia, cough, expiratory dyspnea are postponed
Listing and the upper vicious circle of management etc., make pig production suffer heavy losses.The generation of China's porcine respiratory disease syndrome
More serious, all there is the cause of disease or factor that induction porcine respiratory disease syndrome occurs in almost all of pig farm, during morbidity
Often there is secondary, mixed infection, disease is caused to cause confusion in diagnosis and prevention and control, larger economic damage is brought to pig farm
It loses.
Invention content
The defects of present invention is directed to above in the prior art provides a kind of livestock and poultry cultivation air modifying agent, air improvement
Agent can improve the air of livestock and poultry farm, improve smell, animal can be made to generate refrigerant sense.
A kind of livestock and poultry cultivation air modifying agent, in parts by weight, including 15-20 parts of thyme essential oil, Peppermint essential oil
390-490 parts, 1-2 parts of eucalyptus oil, 10-120 parts of 110-120 parts of ethyl alcohol and purified water.
Further, by menthol (C10H20O it) counts, total alcohol amount is 45~55 (mg/ml) in the air modifying agent.
Further, in parts by weight, including 15 parts of thyme essential oil, 420 parts of Peppermint essential oil, 1 part of eucalyptus oil, ethyl alcohol
120 parts and 85 parts of purified water.
Further, in parts by weight, including 18 parts of thyme essential oil, 450 parts of Peppermint essential oil, 2 parts of eucalyptus oil, ethyl alcohol
120 parts and 50 parts of purified water.
Further, in parts by weight, including 20 parts of thyme essential oil, 490 parts of Peppermint essential oil, 1 part of eucalyptus oil, ethyl alcohol
120 parts and 10 parts of purified water.
The present invention also provides the preparation methods of livestock and poultry cultivation air modifying agent, include the following steps:
S1:Weigh ethyl alcohol, eucalyptus oil, Peppermint essential oil, thyme essential oil and purified water respectively according to parts by weight, it is spare;
S2:Eucalyptus oil, Peppermint essential oil, thyme essential oil in step S1 is added in ethyl alcohol and is uniformly mixed to obtain mixture
A;
S3:Mixture A is added in, mixture B is uniformly mixed to obtain in purified water;
S4:Mixture B is filtered up to livestock and poultry cultivation air modifying agent.
The present invention also provides livestock and poultry cultivation air modifying agents to prepare the medicine for preventing and treating porcine respiratory disease
Application in object.
Further, when preparing the drug for treating porcine respiratory disease, the dosage of the preparation is:
Preparation 100ml is taken to be watered 500 kilograms, continuously drinks within 24 hours, is used in conjunction 3-4 days.
Further, when preparing the drug for preventing porcine respiratory disease, the dosage of the preparation is:By institute
It states preparation and adds in the solution that water is configured to 2%, spray 2-4 times within every 24 hours.
Further, the temperature of the water is no more than 40 degree.
Compared with prior art, the present invention has at least the following advantages:
1. livestock and poultry cultivation air modifying agent provided by the invention cannot be only used for air purification, it may also be used for purification of water quality
Deng as feed antioxidant to prevent generation of feed mold and mycotoxin etc..
2. livestock and poultry cultivation air modifying agent provided by the invention mainly based on volatile oil, is sprayed into air, animal
After sucking, volatile oil can have animal respiratory fine health protection and therapeutic action, can effectively alleviate breathing problem and breathing
Difficulty, strength dissolve sputum, prevent growth of the bacterial virus in respiratory tract, and by stimulating body immune system, be allowed to
Endogenous interferon is generated, to inhibit the duplication of virus.
3. livestock and poultry cultivation air modifying agent provided by the invention can improve the immunocompetence and anti-stress ability of animal, carry
The resistance of high animal body, can effectively slow down stress, reduce morbidity chance, ensure healthy growth.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, below to the technical side in the embodiment of the present invention
Case is clearly and completely described, it is clear that described embodiment is the reality of part of the embodiment of the present invention rather than whole
Apply example.Therefore, the range of claimed invention is not intended to limit to the detailed description of the embodiment of the present invention below, and
It is the selected embodiment for being merely representative of the present invention.Based on the embodiments of the present invention, those of ordinary skill in the art are not making
Go out all other embodiments obtained under the premise of creative work, shall fall within the protection scope of the present invention.
Below by specific embodiment, the present invention is further illustrated.
In the formula of the present invention, the characteristics of each component and function is as follows:
Thyme essential oil:Most one of essential oil of preservative efficacy, can antibacterial, antiviral, effectively inhibit dandruff and shave one's head,
Treatment flu, cough gargle and have a sore throat.
Peppermint essential oil:With double effects, heat when can it is refrigerant, cold when then can warm body, therefore it treat flu
The effect of it is excellent, the symptom generated to respiratory tract is fine, has for dry cough, asthma, bronchitis, pneumonia, pulmonary tuberculosis certain
The effect of.It is also very helpful to gastral disease, play the role of eliminating flatulence, relieve stomachache and heartburn;In addition, it can subtract
Light pain is also effective to migraine, moreover it is possible to which that help is brought down a fever.
Eucalyptus oil:With bactericidal effect, pharmaceutical products are largely used to, can also make cough syrup, chewing gum, gargle, tooth
The odorant of cream, air sanitizer etc..
Ethyl alcohol, menthol are commercially available.
A kind of livestock and poultry cultivation air modifying agent, in parts by weight, including 15-20 parts of thyme essential oil, Peppermint essential oil
390-490 parts, 1-2 parts of eucalyptus oil, 10-120 parts of 110-120 parts of ethyl alcohol and purified water.
Wherein, by menthol (C10H20O it) counts, total alcohol amount is 45~55 (mg/ml) in the air modifying agent.
The preparation method of livestock and poultry cultivation air modifying agent provided by the invention, includes the following steps:
S1:Weigh ethyl alcohol, eucalyptus oil, Peppermint essential oil, thyme essential oil and purified water respectively according to parts by weight, it is spare;
S2:Eucalyptus oil, Peppermint essential oil, thyme essential oil in step S1 is added in ethyl alcohol and is uniformly mixed to obtain mixture
A;
S3:Mixture A is added in, mixture B is uniformly mixed to obtain in purified water;
S4:Mixture B is filtered up to livestock and poultry cultivation air modifying agent.
Each embodiment that specific embodiment is seen below.
Embodiment 1
A kind of livestock and poultry cultivation air modifying agent, in parts by weight, component and content are as shown in table 1.
The component and content of livestock and poultry cultivation air modifying agent in 1 embodiment 1 of table
Ingredient |
Content (part) |
Thyme essential oil |
16 |
Peppermint essential oil |
390 |
Eucalyptus oil |
1 |
Ethyl alcohol |
110 |
Purified water |
120 |
Preparation method includes the following steps:
S1:Weigh ethyl alcohol, eucalyptus oil, Peppermint essential oil, thyme essential oil and purified water respectively according to parts by weight, it is spare;
S2:Eucalyptus oil, Peppermint essential oil, thyme essential oil in step S1 is added in ethyl alcohol and is uniformly mixed to obtain mixture
A;
S3:Mixture A is added in, mixture B is uniformly mixed to obtain in purified water;
S4:Mixture B is filtered up to livestock and poultry cultivation air modifying agent.
Embodiment 2
A kind of livestock and poultry cultivation air modifying agent, in parts by weight, component and content are as shown in table 2.
The component and content of livestock and poultry cultivation air modifying agent in 2 embodiment 2 of table
Ingredient |
Content (part) |
Thyme essential oil |
15 |
Peppermint essential oil |
420 |
Eucalyptus oil |
1 |
Ethyl alcohol |
120 |
Purified water |
85 |
Preparation method includes the following steps:
S1:Weigh ethyl alcohol, eucalyptus oil, Peppermint essential oil, thyme essential oil and purified water respectively according to parts by weight, it is spare;
S2:Eucalyptus oil, Peppermint essential oil, thyme essential oil in step S1 is added in ethyl alcohol and is uniformly mixed to obtain mixture
A;
S3:Mixture A is added in, mixture B is uniformly mixed to obtain in purified water;
S4:Mixture B is filtered up to livestock and poultry cultivation air modifying agent.
Embodiment 3
A kind of livestock and poultry cultivation air modifying agent, in parts by weight, component and content are as shown in table 3.
The component and content of livestock and poultry cultivation air modifying agent in 3 embodiment 3 of table
Ingredient |
Content (part) |
Thyme essential oil |
18 |
Peppermint essential oil |
450 |
Eucalyptus oil |
2 |
Ethyl alcohol |
120 |
Purified water |
50 |
Preparation method is the same as embodiment 2.
Embodiment 4
A kind of livestock and poultry cultivation air modifying agent, in parts by weight, component and content are as shown in table 4.
The component and content of livestock and poultry cultivation air modifying agent in 4 embodiment 4 of table
Ingredient |
Content (part) |
Thyme essential oil |
20 |
Peppermint essential oil |
490 |
Eucalyptus oil |
1 |
Ethyl alcohol |
120 |
Purified water |
10 |
Preparation method is the same as embodiment 2.
The measure of the total alcohol amount of 5 livestock and poultry cultivation air modifying agent of embodiment
Using total alcohol amount of gas Chromatographic Determination livestock and poultry cultivation air modifying agent.
1) preparation of contrast solution:Take menthol reference substance appropriate, it is accurately weighed, add absolute ethyl alcohol be made every 1ml containing about
The solution of 1mg is to get reference substance solution.
2) preparation of test solution:Essence takes this product 1.0ml, puts in 50ml measuring bottles, and absolute ethyl alcohol is added to dissolve and be diluted to
Scale is shaken up to get test solution.
3) assay method:It is accurate respectively to draw reference substance solution and each 1ul of test solution, gas chromatograph is injected, is surveyed
It is fixed.
Chromatographic condition:Using crosslinking bonding polyethylene glycol as the capillary column of stationary phase;120 DEG C of column temperature;Injector temperature 250
℃;250 DEG C of detector temperature;Split ratio 10:1.Number of theoretical plate is calculated by menthol peak should be not less than 10000.
The content X for representing menthol with the percentage of solution is calculated as follows:
In formula:AS--- the peak area of test solution;
Wr--- the sampling amount (g) of reference substance (standard);
CS--- the concentration of test solution;
Ar--- the trap of reference substance (standard);
The concentration of d --- reference substance (standard) solution.
The arithmetic mean of instantaneous value for taking parallel determinations is measurement result, and the relative deviation of parallel determinations is not more than
10%.
According to the above method measure livestock and poultry cultivation air modifying agent in embodiment 1-4 total alcohol amount be respectively 39.7,42.5,
45.5、49.6。
Application of the 6 livestock and poultry cultivation air modifying agent of embodiment in the drug for preventing livestock and birds respiratory disease is prepared
When preparing the drug for preventing porcine respiratory disease, the dosage of the preparation is:The preparation is added
Enter the solution that water is configured to 2%, spray 2-4 times within every 24 hours, wherein, the temperature of the water is no more than 40 degree.
Certain pig farm of Jinan City selection age in days, the close health pig of weight 300 are tested, its stochastic averagina is divided into two
Group:One group is control group, and one group is experimental group.Wherein, control group, which uses, sprays water as control, and it is made that experimental group sprays embodiment 3
Standby livestock and poultry cultivation air modifying agent, Follow-up observation 1 year carry out daily observation to test pig and detection, experimental result are as follows:
Compared with the control group, experimental group porcine respiratory disease incidence is decreased obviously, and incidence is 18% in control group, and
The incidence of experimental group is less than 1%, and the adding weight of pig is apparently higher than control group in experimental group.
The livestock and poultry cultivation air modifying agent that other embodiments of the invention provide also has similar experimental result.
Application of the 7 livestock and poultry cultivation air modifying agent of embodiment in the drug for treating livestock and birds respiratory disease is prepared
When preparing the drug for treating porcine respiratory disease, the dosage of the preparation is:Preparation 100ml is taken to convert
500 kilograms of water is continuously drunk, is used in conjunction 3-4 days for 24 hours.
Suffer from breathing problem piglet 80 are selected, stochastic averagina is divided into 2 groups, and one group is control group, and one group is experimental group.
Wherein, experimental group drinks the livestock and poultry cultivation air modifying agent prepared by embodiment 3, and control group is treated, and just using conventional western medicine
Often drinking-water.The rehabilitation situation and mental status of pig are observed and recorded in experimental period daily, calculates daily gain, feedstuff-meat ratio (feeding
Amount/weightening) and rehabilitation rate, experimental result such as table 5.
5 livestock and poultry cultivation air modifying agent of table treats porcine respiratory disease experimental result
Project |
Control group |
Experimental group |
Sb.'s illness took a favorable turn the time |
3 days |
5 days |
Rehabilitation rate |
98% |
95% |
Daily gain |
789g |
521g |
It can be seen that, the livestock and poultry cultivation air modifying agent that the embodiment of the present invention 3 provides can effectively treat pig and exhale from table 5
Tract disease is inhaled, quick, rehabilitation rate is high, and the daily gain of piglet is apparently higher than the data that conventional western medicine is used in control group.
The livestock and poultry cultivation air modifying agent that other embodiments of the invention provide also has similar experimental result.
Its main component of livestock and poultry cultivation air modifying agent provided by the invention is essential oil, and essential oil has high volatile, volatilization
Degree is higher, and the effect generated to body body is relatively faster.The molecular structure of essential oil is very small, is the 1/ of Skin Cell gap
10, therefore with extremely strong penetration, easily absorbed by skin and mucous membrane.All essential oils, which all have, to kill bacterium, inhibits
The effect of flora growth, insect pest, it can also be used for other livestock and poultry, such as chicken farm, fish farm etc..
More than, it is merely preferred embodiments of the present invention, but the protection domain invented is not limited thereto, it is any ripe
Know those skilled in the art in the technical scope disclosed by the present invention, the change or replacement that can be readily occurred in should all be contained
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be subject to the protection domain of claims.