CN107073014A - 利用噻吩并三唑并二氮杂*化合物治疗急性髓细胞白血病和/或急性淋巴细胞性白血病的方法 - Google Patents

利用噻吩并三唑并二氮杂*化合物治疗急性髓细胞白血病和/或急性淋巴细胞性白血病的方法 Download PDF

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Publication number
CN107073014A
CN107073014A CN201580036473.XA CN201580036473A CN107073014A CN 107073014 A CN107073014 A CN 107073014A CN 201580036473 A CN201580036473 A CN 201580036473A CN 107073014 A CN107073014 A CN 107073014A
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compound
acute
formula
leukemia
thienotriazolodiazepine
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CN201580036473.XA
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Chinese (zh)
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凯·诺埃尔
马里亚·E·里韦罗
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Oncoethix GmbH
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Oncoethix GmbH
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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CN201580036473.XA 2014-05-02 2015-05-01 利用噻吩并三唑并二氮杂*化合物治疗急性髓细胞白血病和/或急性淋巴细胞性白血病的方法 Pending CN107073014A (zh)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201461987822P 2014-05-02 2014-05-02
US61/987,822 2014-05-02
US201461990465P 2014-05-08 2014-05-08
US61/990,465 2014-05-08
US201462012128P 2014-06-13 2014-06-13
US201462012135P 2014-06-13 2014-06-13
US62/012,135 2014-06-13
US62/012,128 2014-06-13
US201462080771P 2014-11-17 2014-11-17
US201462080804P 2014-11-17 2014-11-17
US62/080,804 2014-11-17
US62/080,771 2014-11-17
US201462086456P 2014-12-02 2014-12-02
US62/086,456 2014-12-02
PCT/US2015/028891 WO2015168621A1 (en) 2014-05-02 2015-05-01 Method of treating acute myeloid leukemia and/or acute lymphoblastic leukemia using thienotriazolodiazepine compounds

Publications (1)

Publication Number Publication Date
CN107073014A true CN107073014A (zh) 2017-08-18

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Family Applications (1)

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CN201580036473.XA Pending CN107073014A (zh) 2014-05-02 2015-05-01 利用噻吩并三唑并二氮杂*化合物治疗急性髓细胞白血病和/或急性淋巴细胞性白血病的方法

Country Status (10)

Country Link
US (1) US9956228B2 (https=)
EP (1) EP3137085A4 (https=)
JP (1) JP2017514909A (https=)
KR (1) KR20160145833A (https=)
CN (1) CN107073014A (https=)
AU (1) AU2015252844A1 (https=)
CA (1) CA2947601A1 (https=)
MX (1) MX2016014301A (https=)
RU (1) RU2016146099A (https=)
WO (1) WO2015168621A1 (https=)

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EA034972B1 (ru) 2014-04-23 2020-04-13 Инсайт Корпорейшн 1h-пирроло[2,3-c]пиридин-7(6h)-оны в качестве ингибиторов белков bet
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EP3615020B1 (en) * 2017-04-26 2024-04-10 University of Cincinnati Methods, agents, and compositions for the treatment of acute myeloid leukemia
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US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms
KR20240028420A (ko) 2021-06-08 2024-03-05 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 항암 화합물

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