CN107072204A - 用于减轻阿片类药物诱导型欣快症的系统和方法 - Google Patents

用于减轻阿片类药物诱导型欣快症的系统和方法 Download PDF

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Publication number
CN107072204A
CN107072204A CN201580055965.3A CN201580055965A CN107072204A CN 107072204 A CN107072204 A CN 107072204A CN 201580055965 A CN201580055965 A CN 201580055965A CN 107072204 A CN107072204 A CN 107072204A
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CN
China
Prior art keywords
buprenorphine
opioid drug
another opioid
another
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580055965.3A
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English (en)
Chinese (zh)
Inventor
米凯莱·赫梅尔
唐纳德·J·凯尔
加思·怀特赛德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Pharma LP
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Purdue Pharma LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Purdue Pharma LP filed Critical Purdue Pharma LP
Publication of CN107072204A publication Critical patent/CN107072204A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201580055965.3A 2014-09-12 2015-09-14 用于减轻阿片类药物诱导型欣快症的系统和方法 Pending CN107072204A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462049989P 2014-09-12 2014-09-12
US62/049,989 2014-09-12
US201462065393P 2014-10-17 2014-10-17
US62/065,393 2014-10-17
PCT/US2015/049948 WO2016040934A1 (en) 2014-09-12 2015-09-14 Systems and methods for attenuating opioid-induced euphoria

Publications (1)

Publication Number Publication Date
CN107072204A true CN107072204A (zh) 2017-08-18

Family

ID=55453711

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580055965.3A Pending CN107072204A (zh) 2014-09-12 2015-09-14 用于减轻阿片类药物诱导型欣快症的系统和方法

Country Status (11)

Country Link
US (2) US20160074387A1 (enExample)
EP (1) EP3190890A4 (enExample)
JP (1) JP2017526719A (enExample)
KR (1) KR20170052644A (enExample)
CN (1) CN107072204A (enExample)
AU (1) AU2015314714A1 (enExample)
CA (1) CA2961009A1 (enExample)
IL (1) IL251049A0 (enExample)
MA (1) MA40333A (enExample)
TW (1) TW201613590A (enExample)
WO (1) WO2016040934A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018125716A1 (en) 2017-01-02 2018-07-05 Purdue Pharma L.P. Morphinan derivatives and use thereof
CA3068036A1 (en) * 2017-06-30 2019-01-03 Purdue Pharma L.P. Use to buprenorphine in combination with an opioid to treat pain
AU2018351502B2 (en) * 2017-10-20 2024-09-05 Purdue Pharma L.P. Pharmaceutical dosage forms

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101374521A (zh) * 2006-01-27 2009-02-25 欧洲凯尔特公司 防篡改剂型
WO2011109743A2 (en) * 2010-03-04 2011-09-09 Rand Jerry N Synergistic effects of combinations of buprenorphine and opioids for the treatment of pain
US20130303561A1 (en) * 2012-04-17 2013-11-14 Purdue Pharma L.P. Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
CN103547267A (zh) * 2010-11-08 2014-01-29 奥默罗斯公司 使用pde7抑制剂治疗成瘾和冲动控制障碍

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1613266A4 (en) * 2003-04-15 2009-05-06 Theraquest Biosciences Llc METHOD FOR TREATING PAIN AND COMPOSITIONS FOR USE THEREOF
US20090246265A1 (en) * 2008-03-26 2009-10-01 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101374521A (zh) * 2006-01-27 2009-02-25 欧洲凯尔特公司 防篡改剂型
WO2011109743A2 (en) * 2010-03-04 2011-09-09 Rand Jerry N Synergistic effects of combinations of buprenorphine and opioids for the treatment of pain
CN103547267A (zh) * 2010-11-08 2014-01-29 奥默罗斯公司 使用pde7抑制剂治疗成瘾和冲动控制障碍
US20130303561A1 (en) * 2012-04-17 2013-11-14 Purdue Pharma L.P. Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陈孝治等: "《药物处方手册》", 25 April 2010, 湖南科学技术出版社 *

Also Published As

Publication number Publication date
WO2016040934A1 (en) 2016-03-17
JP2017526719A (ja) 2017-09-14
IL251049A0 (en) 2017-04-30
MA40333A (fr) 2016-03-17
AU2015314714A1 (en) 2017-03-09
KR20170052644A (ko) 2017-05-12
EP3190890A4 (en) 2018-04-25
EP3190890A1 (en) 2017-07-19
US20200276187A1 (en) 2020-09-03
US20160074387A1 (en) 2016-03-17
CA2961009A1 (en) 2016-03-17
TW201613590A (en) 2016-04-16

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Application publication date: 20170818