CA2961009A1 - Systems and methods for attenuating opioid-induced euphoria - Google Patents

Systems and methods for attenuating opioid-induced euphoria Download PDF

Info

Publication number
CA2961009A1
CA2961009A1 CA2961009A CA2961009A CA2961009A1 CA 2961009 A1 CA2961009 A1 CA 2961009A1 CA 2961009 A CA2961009 A CA 2961009A CA 2961009 A CA2961009 A CA 2961009A CA 2961009 A1 CA2961009 A1 CA 2961009A1
Authority
CA
Canada
Prior art keywords
buprenorphine
opioid
administered
mcg
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2961009A
Other languages
English (en)
French (fr)
Inventor
Michele Hummel
Donald J. Kyle
Garth Whiteside
Original Assignee
Purdue Pharma LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Pharma LP filed Critical Purdue Pharma LP
Publication of CA2961009A1 publication Critical patent/CA2961009A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2961009A 2014-09-12 2015-09-14 Systems and methods for attenuating opioid-induced euphoria Abandoned CA2961009A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462049989P 2014-09-12 2014-09-12
US62/049,989 2014-09-12
US201462065393P 2014-10-17 2014-10-17
US62/065,393 2014-10-17
PCT/US2015/049948 WO2016040934A1 (en) 2014-09-12 2015-09-14 Systems and methods for attenuating opioid-induced euphoria

Publications (1)

Publication Number Publication Date
CA2961009A1 true CA2961009A1 (en) 2016-03-17

Family

ID=55453711

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2961009A Abandoned CA2961009A1 (en) 2014-09-12 2015-09-14 Systems and methods for attenuating opioid-induced euphoria

Country Status (11)

Country Link
US (2) US20160074387A1 (enExample)
EP (1) EP3190890A4 (enExample)
JP (1) JP2017526719A (enExample)
KR (1) KR20170052644A (enExample)
CN (1) CN107072204A (enExample)
AU (1) AU2015314714A1 (enExample)
CA (1) CA2961009A1 (enExample)
IL (1) IL251049A0 (enExample)
MA (1) MA40333A (enExample)
TW (1) TW201613590A (enExample)
WO (1) WO2016040934A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2716570T3 (es) 2012-04-17 2019-06-13 Purdue Pharma Lp Sistemas y procedimientos para tratar o prevenir una respuesta farmacodinámica adversa inducida por opioides
US10745402B2 (en) 2017-01-02 2020-08-18 Purdue Pharma L.P. Morphinan derivatives and use thereof
JP2020526500A (ja) 2017-06-30 2020-08-31 パーデュー、ファーマ、リミテッド、パートナーシップ 治療方法及びその剤形
CA3075292A1 (en) * 2017-10-20 2019-04-25 Purdue Pharma L.P. Pharmaceutical dosage forms

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040209850A1 (en) * 2003-04-15 2004-10-21 Theraquest Biosciences, Llc Methods of treating pain and compositions for use therefor
EP1813276A1 (en) * 2006-01-27 2007-08-01 Euro-Celtique S.A. Tamper resistant dosage forms
CA2718943A1 (en) * 2008-03-26 2009-10-01 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
WO2011109743A2 (en) * 2010-03-04 2011-09-09 Rand Jerry N Synergistic effects of combinations of buprenorphine and opioids for the treatment of pain
KR102385359B1 (ko) * 2010-11-08 2022-04-11 오메로스 코포레이션 Pde7 억제제를 사용한 중독 및 충동-조절 장애의 치료
ES2716570T3 (es) * 2012-04-17 2019-06-13 Purdue Pharma Lp Sistemas y procedimientos para tratar o prevenir una respuesta farmacodinámica adversa inducida por opioides

Also Published As

Publication number Publication date
EP3190890A1 (en) 2017-07-19
US20160074387A1 (en) 2016-03-17
JP2017526719A (ja) 2017-09-14
KR20170052644A (ko) 2017-05-12
IL251049A0 (en) 2017-04-30
EP3190890A4 (en) 2018-04-25
CN107072204A (zh) 2017-08-18
WO2016040934A1 (en) 2016-03-17
MA40333A (fr) 2016-03-17
AU2015314714A1 (en) 2017-03-09
US20200276187A1 (en) 2020-09-03
TW201613590A (en) 2016-04-16

Similar Documents

Publication Publication Date Title
US12582647B2 (en) Systems and methods for treating an opioid-induced adverse pharmacodynamic response
US20200276187A1 (en) Systems and methods for attenuating opioid-induced euphoria
US10226457B2 (en) Systems and methods for treating an opioid-induced adverse pharmacodynamic response

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20211207